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deep learning-based air pollution analysis on carbon monoxide in Taiwan

Ecological Informatics 2024年 80卷

作者： Cheng-Hong Yang Po-Hung Chen Chih-Hsien Wu Cheng-San Yang Li-Yeh Chuang Department of Information Management Tainan University of Technology Tainan Taiwan Department of Electronic Engineering National Kaohsiung University of Science and Technology Kaohsiung Taiwan Ph. D. Program in Biomedical Engineering Kaohsiung Medical University Kaohsiung Taiwan School of Dentistry Kaohsiung Medical University Kaohsiung Taiwan Drug Development and Value Creation Research Center Kaohsiung Medical University Kaohsiung Taiwan Division of Plastic and Reconstruction Surgery Department of Surgery Ditmanson Medical Foundation Chia-Yi Christian Hospital Chia-Yi Taiwan Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering I-Shou University Kaohsiung Taiwan

Global air pollution poses a threat to humanity. Specifically, CO directly affects cardiovascular and other organ tissues and leads to numerous chronic diseases and major public health problems. The effective implementation of a deep learning model for predicting variations in CO levels would enable the early formulation of policies for controlling air pollution. In this study, a seasonal gated recurrent unit (SGRU) model, which is a deep learning time-series prediction model, was developed to predict the levels of CO in Taiwan. Atmosph.ric CO measurements from 2005 to 2021 were collected from the Environmental Protection Administration of Taiwan and preprocessed using the Kalman filter to achieve accurate forecasting. The performance of the proposed SGRU model was compared with that of the autoregressive integrated moving average (ARIMA), seasonal ARIMA, exponential smoothing (ETS), Holt–Winters ETS, support vector regression, and seasonal long short-term memory models in terms of mean absolute percentage error (MAPE) and root mean square error. The SGRU model achieved the lowest MAPE value of 0.94, which demonstrated its superior performance. The construction of an accurate air pollution prediction model can assist government entities in formulating health and social care strategies and in planning future air pollution control measures.

关键词： Air pollution Carbon Monoxide (CO) deep learning Seasonal gated recurrent unit (SGRU)

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Current compensation in three‐ph.se power systems

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European Transactions on Electrical Power 1993年第1期3卷 61-66页

作者： Willems, J.L. Prof. Dr.-Ing. Jacques L. Willems (1939) received a degree in electro-mechanical engineering from the University of Gent. Gent/Belgium the Sc. M. degree in electrical engineering from the Massachusetts Institute of Technology Cambridge and the Ph. D. degree in applied science from the University of Gent in 1963 1964 and 1967 respectively. In 1964 he joined the Engineering Faculty of the University of Gent where he is presently Professor of Electrical Engineering. Since October 1988 he has been Dean of the Engineering Faculty. In 1970 he was on leave at the Division of Engineering and Applied Physics of Harvard University Cambridge Mass./USA. In 1982 he was a Visiting Professor at the Universitk Nationale du Rwanda (Central Africa). His teaching and research interests include power system analysis and control system stability theory. (University of Gent Grote Steenweg Noord 6 8-9052 Gent (Zwijnaarde) Belgium T +3291/645653 Fax +3291/645840)

In this paper the compensation of reactive and unbalanced currents in three‐ph.se power systems is discussed. The main result proved is that in sinusoidal steady state any current which corresponds to zero total active power can be compensated by means of a reactive element;the compensation of the reactive currents and the compensation of the unbalanced currents in three‐ph.se power systems are special cases of this result. The explicit expression of the compensating reactances is derived and the multiplicity of the solutions is discussed. The result is illustrated on some examples. Copyright © 1993 John Wiley & Sons, Ltd.

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Assessment of sources and health risks of heavy metals in metropolitan household dust among preschool children: The LEAPP-HIT study

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Journal of Environmental Management 2024年 352卷 120015页

作者： Kao, Chi-Sian Wang, Ying-Lin Jiang, Chuen-Bin Tai, Pei-Ju Chen, Yi-Hua Chao, Hsing-Jasmine Lo, Yu-Chun Hseu, Zeng-Yei Hsi, Hsing-Cheng Chien, Ling-Chu School of Public Health College of Public Health Taipei Medical University Taipei Taiwan Graduate Institute of Environmental Engineering National Taiwan University Taipei Taiwan Department of Pediatric Gastroenterology Hepatology and Nutrition MacKay Children's Hospital Taipei Taiwan Department of Medicine MacKay Medical College SanZhi District New Taipei City Taiwan Neuroscience Research Center Taipei Medical University Taipei Taiwan Ph.D. Program in Medical Neuroscience College of Medical Science and Technology Taipei Medical University Taipei Taiwan Department of Agricultural Chemistry National Taiwan University Taipei Taiwan Nutrition Research Center Taipei Medical University Hospital Taipei Taiwan

The most common construction material used in Taiwan is concrete, potentially contaminated by geologic heavy metals (HMs). Younger children spend much time indoors, increasing HM exposure risks from household dust owing to their behaviors. We evaluated arsenic (As), cadmium (Cd), and lead (Pb) concentrations in fingernails among 280 preschoolers between 2017 and 2023. We also analyzed HM concentrations, including As, Cd, Pb, chromium (Cr), nickel (Ni), copper (Cu), zinc (Zn), iron (Fe), and manganese (Mn), in 90 household dust and 50 road dust samples from a residential area where children lived between 2019 and 2021 to deepen the understanding of sources and health risks of exposure to HMs from household dust. The average As, Cd, and Pb concentrations in fingernails were 0.12 ± 0.06, 0.05 ± 0.05, and 0.95 ± 0.77 μg/g, respectively. Soil parent materials, indoor construction activities, vehicle emissions, and mixed indoor combustion were the pollution sources of HMs in household dust. Higher Cr and Pb levels in household dust may pose non-carcinogenic risks to preschoolers. Addressing indoor construction and soil parent materials sources is vital for children's health. The finding of the present survey can be used for indoor environmental management to reduce the risks of HM exposure and avoid potential adverse health effects for younger children. © 2024 Elsevier Ltd

关键词： Heavy metals

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Peptide-Coated Bacteriorhodopsin-Based ph.toelectric Biosensor for detecting Rheumatoid Arthritis

Biosensors

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Biosensors 2023年第10期13卷 929-929页

作者： Chen, Hsiu-Mei Tsai, Yi-Hsuan Hsu, Chien-Yi Wang, Yong-Yi Hsieh, Cheng-En Chen, Jin-Hua Chang, Yu-Sheng Lin, Ching-Yu Department of Chemical Engineering National Taiwan University of Science and Technology Taipei10607 Taiwan Department of Family Medicine Wan Fang Hospital Taipei Medical University Taipei11696 Taiwan Division of Cardiology and Cardiovascular Research Center Department of Internal Medicine Taipei Medical University Hospital Taipei11031 Taiwan Division of Cardiology Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Taipei Heart Institute Taipei Medical University Taipei11031 Taiwan Graduate Institute of Data Science College of Management Taipei Medical University Taipei11031 Taiwan Office of Data Science Taipei Medical University Taipei11031 Taiwan Division of Allergy Immunology and Rheumatology Department of Internal Medicine Shuang Ho Hospital Taipei Medical University New Taipei City23561 Taiwan Division of Allergy Immunology and Rheumatology Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan School of Medical Laboratory Science and Biotechnology College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Ph.D. Program in Medical Biotechnology College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan

An effective early diagnosis is important for rheumatoid arthritis (RA) management. This study reveals a novel RA detection method using bacteriorhodopsin as a ph.toelectric transducer, a light-driven proton pump in purple membranes (PMs). It was devised by covalently conjugating a PM monolayer-coated electrode with a citrullinated-inter-alph.-trypsin inhibitor heavy chain 3 (ITIH3)542–556 peptide that recognizes the serum RA-associated autoantibodies. The direct serum coating decreased the ph.tocurrents in the biosensor, with the reduction in the ph.tocurrent caused by coating with an RA-patient serum that is significantly larger than that with a healthy-control serum (38.1% vs. 20.2%). The difference in the reduction in the ph.tocurrent between those two serum groups widened after the serum-coated biosensor was further labeled with gold nanoparticle (AuNP)-conjugated anti-IgA (anti-IgA-AuNP) (53.6% vs. 30.6%). Both atomic force microscopic (AFM) and Raman analyses confirmed the sequential peptide, serum, and anti-IgA-AuNP coatings on the PM-coated substrates. The reductions in the ph.tocurrent measured in both the serum and anti-IgA-AuNPs coating steps correlated well with the results using commercial enzyme-linked immunosorbent assay kits (Spearman rho = 0.805 and 0.787, respectively), with both a sensitivity and specificity close to 100% in both steps. It was shown that an RA diagnosis can be performed in either a single- or two-step mode using the developed biosensor. © 2023 by the authors.

关键词： Peptides

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FLAMMABILITY ANd TOXICITY OF COMPOSITE-MATERIALS FOR MARINE VEHICLES

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NAVAL ENGINEERS JOURNAL 1990年第5期102卷 45-54页

作者： SEVART, JL GRIFFIN, OH GURdAL, Z WARNER, GA Jeffrey L. Sevart:is a native of Kansas and a 1985 graduate of Kansas State University with a B.S. in mechanical engineering (magna cum laude). After working as a stress analysis engineer at Boeing Military Airplane Company in Wichita Kans. he attended Virginia Polytechnic Institute and State University and received an M.S. in engineering mechanics in February 1988. He currently resides in Akron Ohio working as a research engineer in tire composites research at The Goodyear Tire and Rubber Company. O. Hayden Griffin Jr.:received his B.S. and M.S. in mechanical engineering from Texas Tech University in 1970 and 1971 respectively. He received his Ph.D. in engineering mechanics from Virginia Polytechnic Institute and State University in 1980. Prior to joining the faculty of Virginia Polytechnic Institute and State University as associate professor of engineering science and mechanics in September 1985 he was employed at the U.S. Naval Surface Warfare Center (Dahlgren Virginia) BF Goodrich Tire Group (Akron Ohio) the Bendix Advanced Technology Center (Columbia Maryland) and the Johns Hopkins University Applied Physics Laboratory (Laurel Maryland). He is currently an associate director of the Virginia Institute for Material Systems. He is a registered professional engineer in Virginia and is a member of the American Society of Mechanical Engineers and the American Society for Composites. Zafer Gürdal:received his M.S. in mechanical and aerospace engineering from Illinois Institute of Technology in 1981 and his Ph.D. in aerospace engineering from Virginia Polytechnic Institute and State University in 1985. He worked as a research associate in the Aerospace and Ocean Engineering Department at Virginia Tech before joining the Engineering Science and Mechanics Department as an assistant professor in September 1985. Professor Gürdal's research interests include: composite structures failure mechanics of composites structural optimization and damage tolerant design. He is a member of the American Institute

Characteristics of both thermoplastic and thermoset composite materials as they pertain to marine vehicle applications are discussed. Comparison of various material selection factors such as strength, damage and moisture resistance, and flammability and toxicity as well as cost and availability of thermoset and thermoplastic composite materials are presented. Methods for testing and reducing the flammability and toxicity are discussed. Many commercially available composite systems are reported to provide favorable characteristics for marine applications. Although there seems to be a need for improved production technology for thermoplastics, they present potential advantages in ph.sical properties over thermoset composites.

关键词： Composite Materials

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CHEMICAL MASS-BALANCE APPROACH TO FIELd-EVALUATION OF BIOREMEdIATION

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ENVIRONMENTAL PROGRESS 1995年第1期14卷 F2-F3页

作者： SIMS, RC SIMS, JL Utah State University Department of Civil and Environmental Engineering and Utah Water Research Laboratory Logan UT 84322 Professor and Head of the Division of Environmental Engineering at Utah State University. He holds degrees in biology (B.S.) environmental chemistry and biology (M.S.) environmental engineering (M.S.) and biological and agricultural engineering (Ph.D). He has worked as Director of the International Program in Industrial Development Chapel Hill NC as Supervisor of the Environmental Control Laboratory for Mobay Chemical Corporation Charleston SC and as environmental engineer with Research Triangle Institute NC. Dr. Sims currently is involved in teaching research and technology transfer in the area of contaminated soil characterization and remediation. Research Assistant Professor in the Division of Environmental Engineering at Utah State University. She holds degrees in biology (B.S.) environmental chemistry and biology (M.S.) and soil science (M.S.). She has held positions as an Associate in a private consulting firm in Raleigh NC and as Chairperson of the on-site wastewater disposal committee of the State of Utah. Judith Sims is currently involved in teaching research and technology transfer in the area of contaminated soil characterization and remediation.

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dual-Targeting EGCG/NO-Supplying protein assembled nanoparticles with Multi-Synergistic effects against atherosclerosis

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Chemical engineering Journal 2024年 493卷

作者： Lin, Chi Cheng, Tsai-Mu Liu, Yun-Chun Hsu, Fang-Yu Shih, Chun-Ming Tsai, Min-Lang Shih, Chun-Che Mi, Fwu-Long Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei11031 Taiwan The PhD Program for Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Taipei Heart Institute Taipei Medical University Taipei11031 Taiwan Department of Food Science National Taiwan Ocean University Keelung20224 Taiwan Department of Biochemistry and Molecular Cell Biology School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Division of Cardiology and Cardiovascular Research Center Taipei Medical University Hospital Taipei11031 Taiwan Division of Cardiovascular Surgery Department of Surgery Wan Fang Hospital Taipei Medical University Taipei11031 Taiwan Institute of Clinical Medicine School of Medicine National Yang-Ming Chiao Tung University Taipei Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Graduate Institute of Nanomedicine and Medical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan International Ph.D. Program for Cell Therapy and Regeneration Medicine College of Medicine Taipei Medical University Taipei Taiwan

Limited therapeutic options are available to effectively preventing atherosclerosis. Inflammatory endothelial cells, foamy macroph.ges, and high protease levels contribute to atherosclerotic plaque formation. Studies have shown that catechins effectively scavenge reactive oxygen species (ROS), inhibit monocyte adhesion and reduce cholesterol levels, while nitric oxide (NO) enhances endothelial function. However, due to the poor stability and bioavailability of catechins and the toxicity from the burst release of current synthetic small molecules NO donor, effective delivery of these bioactive compounds to treat atherosclerosis is still a challenge. Herein, a catechin/protein-based NO donor co-delivery nanosystem was designed for combinatorial anti-atherosclerotic therapy. We engineered a (−)-epigallocatechin-3-gallate (EGCG)/NO-releasing protein co-assembled nanocomplex based on specific catechin-protein interactions. Furthermore, the nanocomplex was surface modified with fucoidan (Fu), a sulfated polysaccharide with anti-inflammatory activity. This nanocomplex exhibits sensitivity to ROS, ph. and enzymes. The Fu-functionalized nanoparticles specifically accumulates in atherosclerotic plaques mediated by P-selectin on inflamed endothelial cells and scavenger receptor A (SR-A) on foamy macroph.ges. Under environmental stimuli that simulate the condition of plaque, the nanoparticles are readily activated to release EGCG and NO in response to excess ROS and high protease levels, exerting the multi-synergistic anti-atherosclerosic effects on reducing monocyte adhesion, promoting NO production to proliferate endothelial cells, lowering ROS levels, and decreasing the foam cell formation in vitro, and reducing lipid accumulation, plaque size, and inflammatory cytokines release in high-fat diet-induced atherosclerosis model in ApoE−/− mice. The integration of plaques targeting ability and multiple therapeutic functions can provide an advanced therapeutic strategy for athero

关键词： Nitric oxide

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Human systems integration and advanced technology in engineering department workload and manpower reduction

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NAVAL ENGINEERS JOURNAL 2003年第1期115卷 57-65页

作者： Lively, KA Seman, AJ Kirkpatrick, M KENNETH A. LIVELY graduated from the University of Colorado with a BS in applied mathematics and an MS in mathematics in 1976 and from the Massachusetts Institute of Technology with an MS in electrical engineering and the degree ocean engineer in naval architecture and marine engineering in 1984. He retired from the U.S. Navy in 1989 after 23 years of service. Assignments included electrical officer on the USS Constellation (CV 64) project engineer for the DDG 51 machinery control system (NAVSEA) and DDG 51 Technical Director (NAVSEA). He was vice president of the PDI Division of Bird-Johnson Company from July 1989 to November 1998 where he managed various gas turbine and machinery controls related development projects. He joined Anteon Corporation's Systems Engineering Group as senior controls engineer in December 1998 where he provided technical support to the integrated power systems program (NAVSEA PMS 510) and managed the Office of Naval Research Afloat Laboratory. DR. MARK KIRKPATRICK is currently an independent consultant in human factors and work-load/manning analysis and modeling. He holds a Ph.D. degree in experimental psychology from The Ohio State University and has 34 years of experience in applied human factors. From 1982 through 2000 Dr. Kirkpatrick served as the senior vice president of Carlow International. Prior to joining Carlow in 1982 Dr. Kirkpatrick served as a member of the technical staff at North American Rockwell's Missiles Division and as a project director and vice president for Essex Corporation. His areas of expertise include workload simulation task analysis operator-in-the-loop simulation human performance experimentation statistical analysis and human factors T&E. He has directed and/or participated in human factors projects for the U.S. Navy U.S. Army NASA Department of Transportation the U.S. Nuclear Regulatory Commission and private industry. ANTHONY J. SEMAN III is the technical manager for the reduced ship's crew by virtual presence (RSVP) advanced technology d

Aboard current ships, such as the ddG 51, engineering control and damage control activities are manpower intensive. It is anticipated that, for future combatants, the workload demand arising from operation of systems under conditions of normal steaming and during casualty response will need to be markedly reduced via automated monitoring, autonomous control, and other technology initiatives. Current ddG 51 class ships can be considered as a manpower baseline and under Condition III typical engineering control involves seven to eight watchstanders at manned stations in the Central Control Station, the engine rooms and other machinery spaces. In contrast to this manning level, initiatives such as dd 21 and the integrated engineering plant (IEP) envision a partnership between the operator and the automation system, with more and more of the operator's functions being shifted to the automation system as manning levels decrease. This paper describes some human systems integration studies of workload demand reduction and, consequently, manning reduction that can be achieved due to application of several advanced technology concepts. Advanced system concept studies in relation to workload demand are described and reviewed including. Piecemeal applications of diverse automation and remote control technology concepts to selected high driver tasks in current ddG 51 activities. development of the reduced ship's crew by virtual presence system that will provide automated monitoring and display to operators of machinery health, compartment conditions, and personnel health. The IEP envisions the machinery control system as a provider of resources that are used by various consumers around the ship. Resource needs and consumer priorities are at all times dependent upon the ship's current mission and the availability of equipment pawnbrokers.

关键词： Naval warfare

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Meeting the Information Assurance Crisis in the U.S. Now

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EdPACS 2006年第6期28卷 1-14页

作者： Corey Schou deborah Frincke Charles Reynolds James Frost The Associate Dean of Information Systems Programs at Idaho State University (ISU) in Pocatello and the director of the Center for Decision Support. Currently he serves as the Chair of the National Colloquium on Information System Security Education. Schou also directs the ISU National Center of Excellence in Information Assurance Education and the ISU Technology Innovation Center. Contact Corey Schou one of the authors of this article and the Chair of the NCISSE by email at Schou@*** for help in finding additional ways to address the issues raised in this article. A member of the University of Idaho College of Engineering faculty. She graduated from the University of California at Davis. Frincke is the co-director and co-founder of the university's Center for Secure and Dependable Software (CSDS). She was the program chair for the 2nd International Workshop on Recent Advances in Intrusion Detection (RAID). A professor of Computer Science at the College of Integrated Science and Technology at James Madison University in Harrisonburg Virginia. He holds a Ph.D. in computer science from the University of Texas at Austin and a BA in philosophy from the University of Houston. Reynolds is the Director of Information System Security Education at James Madison University. Since 1997 Reynolds has led the development of the first remote Internet-based curriculum that leads to an M.S. degree in computer science with a concentration in information security. Thus far 160 students have completed this program. A professor of computer information systems at Idaho State University and the manager of its Simplot Decision Support Center.

T he only difference etween evolution and revolution is the speed at which each occurs.

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developing a prototype concurrent design tool for composite topside structures

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NAVAL ENGINEERS JOURNAL 1997年第3期109卷 279-290页

作者： dirlik, S Hambric, S Azarm, S Marquardt, M Hellman, A Bartlett, S Castelli, V Steve Dirlik:began his career at the Naval Surface Warfare Center Carderock Division in 1981 as an aerospace engineer co-op student. He completed his bachelor of science degree in aeropace and ocean engineering from Virginia Polytechnic Institute and State University in 1985 and his master of science degree in aerospace engineering from the University of Maryland in 1990. Mr. Dirlik recently completed a master of science program in applied physics at The Johns Hopins University and currently works in the Radar Cross Section and Target Physics Branch of the Signatures Directorate at the Naval Surface Warfare Center Corderoke Division. He has worked on Navy low observable programs since 1990. Stephen Hambric:is a research associate at the Applied Research Laboratory at The Pennsylvania State University. He received his B. S. and M.S. degree in mechanical engineering from Virginia Polytechnic Institute and State University and his D. Sc. in mechnical engineering from the George Washington University. He has worked on several computer aided multidiscikplinary design and optimization projects over the years including an automated propeller design system and a structural acoustic optimization capability. Dr. Shpour Azarm:is currently working as an associate professor with the Design and Manufacturing Group of the Department of Mechanical Engineering at the University of maryland at College Park. Dr Azarm's expertise is in the areas of optimization-based designed and concurrent design and optimization of multidisciplinary systems. He was a consultant at Black & Decker Corporation (summer 1996) and worked as a Navy senior summer faculty fellow (summer 1995) and a NASA summer faculty fellow (summer 1994). He was a visiting scientist at NASA Langley Research Center for Multidisciplinary Analysis and Applied Structural Optimzatiom at the University of Siegen in Germany (spring 1992) and the Design Institute of the Technical University of Denmark (summer 1990). Dr Azarm was an associate technical editor of the ASME Jour

A prototype concurrent engineering tool has been developed for the preliminary design of composite topside structures for modern navy warships. This tool, named GELS for the Concurrent engineering of Layered Structures, provides designers with an immediate assessment of the impacts of their decisions on several disciplines which are important to the performance of a modern naval topside structure, including electromagnetic interference effects (EMI), radar cross section (RCS), structural integrity, cost, and weight. Preliminary analysis modules in each of these disciplines are integrated to operate from a common set of design variables and a common materials database. Performance in each discipline and an overall fitness function for the concept are then evaluated. A graph.cal user interface (GUI) is used to define requirements and to display the results from the technical analysis modules. Optimization techniques, including feasible sequential quadratic programming (FSQP) and exhaustive search are used to modify the design variables to satisfy all requirements simultaneously. The development of this tool, the technical modules, and their integration are discussed noting the decisions and compromises required to develop and integrate the modules into a prototype conceptual design tool.

关键词： Warships

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