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Retraction notice to ‘Applications of engineered biochar in remediation of heavy metal(loid)s pollution from wastewater: Current perspectives toward sustainable development goals’ [Sci. Total Environ., 926 (2024) 171859] (Science of the Total Environment (2024) 926, (S0048969724020023), (10.1016/***.2024.171859))

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Science of the Total Environment 2025年 976卷 179291页

作者： Tran, Thien-Khanh Huynh, Loan Nguyen, Hoang-Lam Nguyen, Minh-Ky Lin, Chitsan Hoang, Tuan-dung Hung, Nguyen Tri Q. Nguyen, X. Hoan Chang, S. Woong Nguyen, d. duc Advanced Applied Sciences Research Group Dong Nai Technology University Bien Hoa City76100 Viet Nam Faculty of Technology Dong Nai Technology University Bien Hoa City76100 Viet Nam Department of Civil Engineering McGill University Montreal Canada Faculty of Environment and Natural Resources Nong Lam University Hamlet 6 Linh Trung Ward Thu Duc City Ho Chi Minh City700000 Viet Nam Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung81157 Taiwan Department of Marine Environmental Engineering National Kaohsiung University of Science and Technology Kaohsiung81157 Taiwan School of Chemistry and Life Science Hanoi University of Science and Technology No. 1 Dai Co Viet Hai Ba Trung Hanoi100000 Viet Nam Vietnam National University Hanoi - School of Interdisciplinary Sciences and Arts 144 Xuan Thuy Street Cau Giay District Hanoi100000 Viet Nam Ho Chi Minh City University of Industry and Trade Ho Chi Minh City Viet Nam Department of Civil & Energy System Engineering Kyonggi University Suwon16227 Korea Republic of Institute of Applied Technology and Sustainable Development Nguyen Tat Thanh University Ho Chi Minh City700000 Viet Nam

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://***/about/policies/article-withdrawal). This article has been retracted at the request of the Authors. The corresponding author approached the journal to make it aware that significant portions of the text of the STOTEN article had already been included in the following publication involving several members of the same authorship group: Minh-Ky Nguyen, Chitsan Lin, Nguyen Tri Quang Hung, Hoang-Lam Nguyen, Hong-Giang Hoang, Huu-Tuan Tran, Mohammed Hadi, Chapter 8 - Biochar and engineering applications in remediation of heavy metal pollutants from wastewater toward sustainable development, Editor(s): Xuan-Thanh Bui, Ashok Pandey, Thanh-Tin Nguyen, Shu-Yuan Pan, Low Cost Water and Wastewater Treatment Systems: Conventional and Recent Advances, Elsevier, 2025, Pages 195-233, ISBN 9780443236624, https://***/10.1016/B978-0-443-23662-4.00016-0. The authors realise that redundant publications overweigh the relative importance of published findings, and therefore requested the retraction of the STOTEN article. The authors also apologies for any inconvenience caused. © 2025 Elsevier B.V.

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OXYGEN-TRANSFER THROUGH FLEXIBLE TUBING ANd ITS EFFECTS ON GROUNd-WATER SAMPLING RESULTS

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GROUNd WATER MONITORING ANd REMEdIATION 1988年第3期8卷 83-89页

作者： HOLM, TR GEORGE, GK BARCELONA, MJ Thomas R. Holm is an associate chemist in the Aquatic Chemistry Section of the Illinois State Water Survey (2204 Griffith Dr. Champaign IL 61820-7495) a division of the Illinois Department of Energy and Natural Resources. His research interests include ground water geochemistry trace-metal speciation and arsenic chemistry. Prior to joining the Water Survey he was a research assistant prof essor at the University of Minnesota (Twin Cities) where he studied the geochemistry of aquifer thermal energy storage. Before that he was a postdoctoral research associate in the Water Chemistry Program of the University of Wisconsin (Madison) where he investigated arsenic speciation and cycling in fresh water sediments. He received his B.S. in chemistry from Portland State University and his M.S. and Ph.D. in environmental engineering science from the California Institute of Technology. Gregory K. George is' an assistant chemist in the Aquatic Chemistry Section of the Illinois State Water Survey (2204 Griffith Dr. Champaign IL 61820-7495). His research work has focused on evaluation and improvement of analytical methods for naturally occurring aquatic organic matter and on the development and validation of analytical and sampling methods for ground water oxidants. He was previously a research technician with the University of Illinois Institute for Environmental Studies where he determined dissolved 226Ra for a ground water treatment project. He received a B.S. in chemistry from the University of Illinois (Urbana-Champaign). Michael J. Barcelona is the head of the Aquatic Chemistry Section of the Illinois State Water Survey (2204 Griffith Dr. Champaign IL 61820-7495). His research interests include ground water geochemistry contaminant detection monitoring and verification techniques with an emphasis on ground water resource protection and management. He has been involved in various aspects of ground water research and policy matters extensively in the past eight years. He has a B.A. in chemistry from St. Mary's

A model for the diffusion of gases through polymeric tubing was derived which predicts that the amount of gas transferred is proportional to the tubing length and inversely proportional to the pumping rate. The model was experimentally tested and confirmed for oxygen transfer through fluorinated ethylene-propylene copolymer (FEP) tubing using tubing lengths and flow rates typical of ground water sampling. diffusion can introduce measurable concentrations of oxygen into initially anoxic water. diffusive loss of carbon dioxide from water that is oversaturated with respect to atmospheric CO 2 does not measurably affect ph under similar usage conditions.

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GENETIC-ENGINEERING ANd ENVIRONMENTAL-POLLUTION - POTENTIAL ANd UNCERTAINTIES

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BIO-TECHNOLOGY 1983年第8期1卷 670-673页

作者： ZABORSKY, OR Oskar R. Zaborsky Ph.D. is a program director in the Division of Chemical and Process Engineering of the National Science Foundation 1800 G Street Washington DC 20550. The views conclusions and recommendations expressed herein are those of the author and do not necessarily reflect the views and policies of the National Science Foundation.REFERENCES Conference on "Genetic Control of Environmental Pollutants" July 31-August 3 1983 University of Washington School of Public Health & Community Medicine and Department of Environmental Health Seattle WA. The proceedings are to be published by Plenum Press.Recent reports covering the handling of hazardous industrial wastes including biological processes are (a) "Management of Hazardous Industrial Wastes: Research and Development Needs" National Research Council National Academy Press Washington D.C. 1983 (b) "Technologies and Management Strategies for Hazardous Waste Control " Congress of the United States Office of Technology Assessment Washington D.C. 1983.An expanded report on the technology market analysis regulatory and legislative factors dealing with biotechnology applications to hazardous wastes has been produced by Dr. Thomas O.Peyton AmTech Consultants Vienna VA for the OTA study.Baross J.A. and Deming J.W.1983. Growth of 'black smoker' bacteria at temperatures of at least 250C. Nature303: 423-426.|Article|ISI|ChemPort|

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Biological Evaluation of Sulfonate and Sulfate Analogues of Lithocholic Acid: A Bioisosterism-Guided Approach Towards the discovery of Potential Sialyltransferase Inhibitors for Antimetastatic Study

SSRN

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SSRN 2023年

作者： Perez, Ser John Lynon P. Chen, Chia-Ling Chang, Tzu-Ting Li, Wen-Shan Institute of Chemistry Academia Sinica Taipei115 Taiwan Department of Applied Chemistry National Yang Ming Chiao Tung University Hsinchu300 Taiwan Sustainable Chemical Science and Technology Taiwan International Graduate Program Academia Sinica Taipei115 Taiwan Biomedical Translation Research Center Academia Sinica Taipei115 Taiwan Department of Medicinal and Applied Chemistry College of Life Science Kaohsiung Medical University Kaohsiung807 Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taiwan Doctoral Degree Program in Marine Biotechnology National Sun Yat-Sen University Kaohsiung804 Taiwan Department of Chemistry College of Science Tamkang University New Taipei City251 Taiwan

The naturally occurring bile acid lithocholic acid (LCA) has been a crucial core structure for many non-sugar-containing sialyltranferase (ST) inhibitors documented in literature. With the aim of elucidating the impact of the terminal carboxyl acid substituent of LCA on its ST inhibition, in this present study, we report the (bio)isosteric replacement-based design and synthesis of sulfonate and sulfate analogues of LCA. Among these compounds, the sulfate analogue SPP-002 was found to selectively inhibit N-glycan sialylation by at least an order of magnitude, indicating a substantial improvement in both potency and selectivity when compared to the unmodified parent bile acid. Molecular docking analysis supported the stronger binding of the synthetic analogue in the enzyme active site. Treatment with SPP-002 also hampered the migration, adhesion, and invasion of MdA-MB-231 cells in vitro by suppressing the expression of signaling proteins involved in the cancer metastasis-associated FAK/paxillin pathway. In totality, these findings offer not only a novel structural scaffold but also valuable insights for the future development of more potent and selective ST inhibitors with potential therapeutic effects against tumor cancer metastasis. © 2023, The Authors. All rights reserved.

关键词： Sulfur compounds

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Air pollution associate with advanced hepatic fibrosis among patients with chronic liver disease

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Kaohsiung Journal of Medical Sciences 2024年第3期40卷 304-314页

作者： Jang, Tyng-Yuan Ho, Chi-Chang Liang, Po-Cheng Wu, Chih-da Wei, Yu-Ju Tsai, Pei-Chien Hsu, Po-Yao Hsieh, Ming-Yen Lin, Yi-Hung Hsieh, Meng-Hsuan Wang, Chih-Wen Yang, Jeng-Fu Yeh, Ming-Lun Huang, Chung-Feng Chuang, Wan-Long Huang, Jee-Fu Cheng, Ya-Yun dai, Chia-Yen Chen, Pau-Chung Yu, Ming-Lung Ph.D. Program in Environmental and Occupational Medicine College of Medicine Kaohsiung Medical University and National Health Research Institutes Kaohsiung Taiwan Hepatobiliary Division Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan College of Medicine and Center for Liquid Biopsy and Cohort Research Kaohsiung Medical University Kaohsiung Taiwan Department of Internal Medicine Pingtung Hospital Ministry of Health and Welfare Ping-Tung Taiwan Institute of Environmental and Occupational Health Sciences National Taiwan University Taipei Taiwan Department of Geomatics National Cheng Kung University Tainan Taiwan Innovation and Development Center of Sustainable Agriculture National Chung Hsing University Tainan Taiwan School of Medicine and Doctoral Program of Clinical and Experimental Medicine College of Medicine and Center of Excellence for Metabolic Associated Fatty Liver Disease National Sun Yat-sen University Kaohsiung Taiwan Department of Public Health National Taiwan University Taipei Taiwan Department of Environmental and Occupational Medicine National Taiwan University Hospital Taipei Taiwan National Institute of Environmental Health Sciences National Health Research Institutes Miaoli Taiwan Division of Hepato-Gastroenterology Department of Internal Medicine Kaohsiung Chang Gung Memorial Hospital Kaohsiung Taiwan

We aimed to investigate the association between air pollution and advanced fibrosis among patients with metabolic associated fatty liver disease (MAFLd) and chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. A total of 1376 participants who were seropositive for HBV surface antigen (HBsAg) or antibodies to HCV (anti-HCV) or had abnormal liver function in a community screening program from 2019 to 2021 were enrolled for the assessment of liver fibrosis using transient elastography. daily estimates of air pollutants (particulate matter ≤2.5 μm in diameter [PM_2.5], nitrogen dioxide [NO₂], ozone [O₃] and benzene) were aggregated into mean estimates for the previous year based on the date of enrolment. Of the 1376 participants, 767 (52.8%) and 187 (13.6) had MAFLd and advanced fibrosis, respectively. A logistic regression analysis revealed that the factors associated with advanced liver fibrosis were HCV viremia (odds ratio [OR], 3.13;95% confidence interval [CI], 2.05–4.77;p < 0.001), smoking (OR, 1.79;95% CI, 1.16–2.74;p = 0.01), age (OR, 1.04;95% CI, 1.02–1.05;p < 0.001) and PM_2.5 (OR, 1.10;95% CI, 1.05–1.16;p < 0.001). Linear regression analysis revealed that LSM was independently correlated with PM_2.5 (β: 0.134;95% CI: 0.025, 0.243;p = 0.02). There was a dose-dependent relationship between different fibrotic stages and the PM_2.5 level (the PM_2.5 level in patients with fibrotic stages 0, 1–2 and 3–4: 27.9, 28.4, and 29.3 μg/m³, respectively;trend p < 0.001). Exposure to PM_2.5, as well as HBV and HCV infections, is associated with advanced liver fibrosis in patients with MAFLd. There was a dose-dependent correlation between PM_2.5 levels and the severity of hepatic fibrosis. © 2023 The Authors. The Kaohsiung Journal of Medical Sciences published by John Wiley & Sons Australia, Ltd on behalf of Kaohsiung Medical University.

关键词： advanced liver fibrosis air pollution MAFLd PM2.5 transient elastography

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Institutional Innovation For Cogeneration

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Review of Policy research 1985年第1期5卷 89-95页

作者： Chartock, Michael A. devine, Michael d. Gunn, Elizabeth M. Currently Staff Scientist in the Office for Planning and Development at the Lawrence Berkeley Laboratory University of California. Formerly he was a Research Fellow in the Science and Public Policy Program and Associate Professor of Zoology at the University of Oklahoma. He has a Ph.D. in Biological Science from the University of Southern California. He is a co-author of five books and numerous papers on energy and environmental issues. Technical Project Coordinator at the Energy Resources Institute at the University of Oklahoma and a Ph.D. candidate in Political Science. She is author with Kenneth J. Meier and Ronald D. Sylvia of The Manager and Program Planning and Evaluotion (Brooks/-Cole 1985). She has also published in edited works on groundwater management in the U.S. and on growth change and environmental quality in the Sunbelt.

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diterpenoids and Their Glycosides from the Stems ofTinospora crispawith Beta-Cell Protective Activity

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Journal of Natural Products 2023年第6期86卷 1437-1448页

作者： Sio-Hong Lam Hui-Kang Liu Shih-Yuan Chung Jia-Ling Chang Mao-Xuan Hong Sheng-Chu Kuo Chih-Chuang Liaw School of Pharmacy College of Medicine National Cheng Kung University Tainan 70101 Taiwan Division of Basic Chinese Medicine National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei 112 Taiwan Ph.D. Program in the Clinical Drug Development of Herbal Medicine Taipei Medical University Taipei 11031 Taiwan Graduate Institute of Pharmaceutical Chemistry China Medical University Taichung 404 Taiwan Department of Marine Biotechnology and Resource National Sun Yat-sen University Kaohsiung 80424 Taiwan Department of Science Application and Dissemination National Taichung University of Education Taichung 403 Taiwan Graduate Institute of Natural Products Kaohsiung Medical University Kaohsiung 807 Taiwan Graduate Institute of Pharmacognosy Taipei Medical University Taipei 11031 Taiwan

Seven previously undescribed diterpenoids, tinocrisposides A–d (1–4) and borapetic acids A (5), B (6), and C (7), together with 16 known compounds, were isolated from the stem ofTinospora crispa(Menispermaceae). The structures of the new isolates were elucidated by spectroscopic and chemical methods. The β-cell protective effect of the tested compounds was examined on insulin-secreting BRIN-Bd11 cells under dexamethasone treatment. diterpene glycosides12,14–16, and18presented a substantial protective effect on BRIN-Bd11 cells treated with dexamethasone in a dose-dependent manner. Compounds4and17with two sugar moieties exhibited clear protective effects on β-cells.

关键词： Alkyls Carbohydrates Carbon Chemical structure Nuclear magnetic resonance spectroscopy

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design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CdK8) inhibitors

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Biomedicine and pharmacotherapy 2023年第1期159卷 114258-114258页

作者： Hsu, Jui-Yi Hsu, Kai-Cheng Sun, Ching Chou, Ching-Hsuan Lin, Tony Eight Sung, Tzu-Ying Tseng, Hui-Ju Yen, Shih-Chung Yang, Chia-Ron Huang, Wei-Jan Ph.D. Program for Cancer Molecular Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University and Academia Sinica Taipei Taiwan Graduate Institute of Cancer Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei Taiwan Ph.D. Program for Cancer Molecular Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei Taiwan TMU Research Center for Drug Discovery Taipei Medical University Taipei Taiwan TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei Taiwan Cancer Center Wan Fang Hospital Taipei Medical University Taipei Taiwan School of Pharmacy College of Medicine National Taiwan University Taipei Taiwan Biomedical Translation Research Center Academia Sinica Taipei Taiwan Department of Pharmacology and Pharmaceutical Sciences School of Pharmacy University of Southern California Los Angeles CA United States Warshel Institute for Computational Biology The Chinese University of Hong Kong (Shenzhen) Guangdong Shenzhen China School of Pharmacy Taipei Medical University Taipei Taiwan

Cyclin-dependent protein kinase 8 (CdK8) plays important roles in regulating fibrotic growth factors and inflammatory signaling pathways. Long-term chronic inflammation of the lungs can lead to idiopathic pulmonary fibrosis (IPF). Abnormal alveolar epithelial regeneration leads to the release of various fibrotic growth factors and the activation of inflammatory cells. CdK8 regulates profibrotic cytokines broadly implicated in the pathogenesis of fibrosis. Therefore, inhibition of CdK8 is considered a promising strategy for treating IPF. Here, CdK8 inhibitors were designed and optimized using a fragment-based drug design strategy. Testing results revealed that 71% of the synthesized compounds inhibited CdK8 activity better than the original compound E966–0530. Of these compounds, compound 4k exhibited the strongest CdK8 enzyme-inhibiting activity (IC₅₀ =129 nM). Notably, it displayed a 13-fold increase in potency when compared to E966–0530. Experiments on toxicity and inhibition of epithelial-mesenchymal transition (EMT) protein expressions showed that compound 4k can inhibit EMT protein expressions, but with no significant cytotoxicity for alveolar epithelial cells. Compound 4k showed a potent inhibitory effect in cell migration assays. Furthermore, compound 4k significantly inhibited the phosphorylation of p-Smad3 and RNA Pol II, which are critical mediators in the fibrotic response signaling pathway. Compound 4k remarkably reduced TGF-β1-induced oxidative stress. The above results reveal optimized CdK8 inhibitors with potential use for IPF therapeutic treatment. © 2023 The Authors

关键词： Cyclin-dependent protein kinase 8 (CdK8) Idiopathic pulmonary fibrosis (IPF) Indolin-2-one Kinase inhibitor Lead optimization

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Enhanced light-driven photoelectrochemical catalysis of water splitting by TiO2 nanotubes grown on acid-etched titanium foils

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International Journal of Hydrogen Energy 2024年第PartA期51卷 1483-1493页

作者： Hsiao, Yu-Cheng Lai, Jhih-Hong Fan, Yu-Min Chen, Hung-Ming Yougbaré, Sibidou Saukani, Muhammad Chen, Chih-Yu Wu, Yung-Fu Lin, Lu-Yin International PhD Program in Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Stanford Byers Center for Biodesign Stanford University CA94305-5428 United States Graduate Institute of Biomedical Optomechatronics College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Department of Chemical Engineering and Biotechnology National Taipei University of Technology Taipei Taiwan Department of Chemical Engineering Ming Chi University of Technology New Taipei City24301 Taiwan Gingen Technology Co. LTD. Rm. 7 10F. No.189 Sec. 2 Keelung Rd. Xinyi Dist. Taipei11054 Taiwan /Nanoro 03 B.P 7192 Ouagadougou03 Burkina Faso Department of Mechanical Engineering Faculty of Engineering Universitas Islam Kalimantan MAB Jl. Adhyaksa No. 2 Banjarmasin70124 Indonesia Department of Orthopedics Shuang Ho Hospital Taipei Medical University New Taipei City23561 Taiwan International Ph.D. Program in Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Cell Physiology and Molecular Image Research Center Wan Fang Hospital Taipei Medical University Taipei11696 Taiwan

Titanium dioxide with suitable band edges is one of promising photocatalysts for water splitting. Nanotubes with one-dimensional structure can induce efficient charge transfers and hollow centers can provide large surface area for surface reactions. Modifying Ti foils for anodization can enhance light utilization of TiO2 nanotube photoelectrodes. In this work, it is firstly to fabricate TiO2 nanotube photoelectrodes on acid-etched Ti foils by anodization (MNT) for photoelectrochemical catalyzing water splitting. different acid-etching durations are applied on Ti foils to induce various rugged surfaces. The resulting photoelectrodes present largely enhanced light utilization than that fabricated by the pristine Ti foil. The anodization duration is also optimized to find suitable lengths of MNT. The smallest overpotential of 524.7 mV at 10 mA/cm2 and Tafel slope of 167 mV/dec are obtained for the optimal MNT photoelectrode. The TiO2 nanotubes grown on the pristine Ti foil shows the overpotential of 679.3 mV at 10 mA/cm2 and Tafel slope of 285 mV/dec. This result opens a blueprint for raising the photocatalytic ability by simply modifying the surface property of the conductive substrate. Other modifications may be applicable to enhance the roughness of Ti foils for growing more efficient MNT array as photocatalysis of water splitting. © 2023 Hydrogen Energy Publications LLC

关键词： Titanium dioxide

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Ganoderma microsporum immunomodulatory protein combined with KRASG12C inhibitor impedes intracellular AKT/ERK network to suppress lung cancer cells with KRAS mutation

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International Journal of Biological Macromolecules 2024年第Part2期259卷

作者： Hua, Wei-Jyun Hwang, Wei-Lun Yeh, Hsin Lin, Zhi-Hu Hsu, Wei-Hung Lin, Tung-Yi Program in Molecular Medicine National Yang Ming Chiao Tung University and Academia Sinica Taipei Taiwan Institute of Traditional Medicine National Yang Ming Chiao Tung University Taipei Taiwan Department of Biotechnology and Laboratory Science in Medicine National Yang Ming Chiao Tung University Taipei Taiwan LO-Sheng Hospital Ministry of Health and Welfare Taipei Taiwan School of Oral Hygiene College of Oral Medicine Taipei Medical University Taipei Taiwan Biomedical Industry Ph.D. Program National Yang Ming Chiao Tung University Taipei Taiwan Cancer and Immunology Research Center National Yang Ming Chiao Tung University Taipei Taiwan

KRAS mutations are tightly associated with lung cancer progression. despite the unprecedented clinical success of KRASG12C inhibitors, recurrent mechanisms of resistance and other KRAS mutations require further therapeutic approaches. GMI, a protein from the medicinal mushroom Ganoderma microsporum, possesses antitumor activity;whereas, the biological function of GMI on regulating KRAS mutant lung cancer cells remains unknown. Herein, RNA-sequencing and bioinformatics showed that GMI may regulate KRAS-modulated MAPK and PI3K-AKT pathways in A549 (KRASG12S) cells. Further experiments demonstrated that GMI inhibited KRAS activation and suppressed ERK1/2 and AKT signaling in A549 cells. Intriguingly, GMI inhibited AKT signaling but increased phosphorylation of ERK in H358 (KRASG12C) cells. GMI significantly suppressed tumor growth in LLC1 cells-allograft and H358 cells-xenograft mice. GMI showed a synergistic effect with KRASG12C inhibitors in inhibiting cell growth, KRAS activation and KRAS-mediated downstream signaling, leading to apoptosis in H358 cells. Combination of GMI and KRASG12C inhibitor, AMG 510, resulted in more durable inhibition of tumor growth and KRAS activity in H358 cells-xenograft mice. This study highlights the potential of GMI, a dietary fungal protein, as a viable therapeutic avenue for KRAS-mutant lung cancer in combination with KRASG12C inhibitors. © 2023

关键词： Proteins

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