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Correction: Interface structure, precursor rheology and dielectric properties of BaTiO3/PVdF–hfp nanocomposite films prepared from colloidal perovskite nanoparticles

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RSC Advances 2017年第73期7卷 45987-45987页

作者： Y. N. Hao K. Bi S. O’Brien X. H. Wang J. Lombardi F. Pearsall W. L. Li M. Lei Y. Wu L. T. Li State Key Laboratory of Information Photonics and Optical Communications School of Science Beijing University of Posts and Telecommunications Beijing 100876 China The Department of Chemistry and Biochemistry The City College of New York The Ph.D. Program in Chemistry The Graduate Center of the City University of New York New York NY 10016 USA State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University Beijing 100084 China School of Journalism and Communication Beijing Normal University Beijing 100875 China

Correction for ‘Interface structure, precursor rheology and dielectric properties of BaTiO3/PVdF–hfp nanocomposite films prepared from colloidal perovskite nanoparticles’ by Y. N. Hao et al., RSC Adv., 2017, 7, 32...

Correction for ‘Interface structure, precursor rheology and dielectric properties of BaTiO₃/PVdF–hfp nanocomposite films prepared from colloidal perovskite nanoparticles’ by Y. N. Hao et al., RSC Adv., 2017, 7, 32886–32892.

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Publisher Correction: Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

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Eye (London, England) 2024年第11期38卷 2229-2231页

作者： Konrad Pesudovs Hugh R. Taylor Tabassom Sedighi Rupert R. A. Bourne Shahina Pardhan Van Charles Lansingh John H. Kempen Ian Tapply Arthur G. Fernandes Maria Vittoria Cicinelli Alessandro Arrigo Nicolas Leveziel Serge Resnikoff Seth Flaxman Mukkharram M. Bikbov Tasanee Braithwaite Alain Bron Ching-Yu Cheng Monte A. del Monte Joshua R. Ehrlich Leon B. Ellwein david Friedman João M. Furtado Gus Gazzard Ronnie George M. Elizabeth Hartnett Jost B. Jonas Rim Kahloun Moncef Khairallah Rohit C. Khanna Janet Leasher Julie-Anne Little Vinay Nangia Michal Nowak Tunde Peto Pradeep Ramulu Fotis Topouzis Mitiadis Tsilimbaris Ya Xing Wang Ningli Wang Paul Svitil Briant Theo Vos Katrin Burkart Kaleb Coberly Xiaochen dai Stephen S. Lim Tomislav Mestrovic Ali H. Mokdad Christopher J. L. Murray Jaimie d. Steinmetz Awoke Misganaw Yohannes Habtegiorgis Abate Mohammad Abdollahi Mozhan Abdollahi Ayele Mamo Abebe Olumide Abiodun Richard Gyan Aboagye Woldu Aberhe Abrha Hasan Abualruz Hiwa Abubaker Ali Eman Abu-Gharbieh Salahdein Aburuz Tadele Girum Girum Adal Mesafint Molla Adane Isaac Yeboah Addo Qorinah Estiningtyas Sakilah Adnani Muhammad Sohail Afzal Muhammad Umair Shahin Aghamiri Bright Opoku Ahinkorah Aqeel Ahmad Sajjad Ahmad Ali Ahmadi Siamak Sabour Ayman Ahmed Haroon Ahmed Ahmad Samir Alfaar Abid Ali Syed Shujait Shujait Ali Awais Altaf Hubert Amu Emmanuel Manu Sofia Androudi Rodrigo Anguita Abhishek Anil Rimple Jeet Kaur Muhammad Aaqib Shamim Saeid Anvari Anayochukwu Edward Anyasodor Francis Appiah Jalal Arabloo Haleh Ayatollahi Mosab Arafat damelash Areda Reza Arefnezhad Brhane Berhe Aregawi Akeza Awealom Asgedom Tahira Ashraf Seyyed Shamsadin Athari Bantalem Tilaye Tilaye Atinafu Birhan Tsegaw Taye Maha Moh’d Wahbi Atout Alok Atreya Ahmed Y. Azzam Hassan Babamohamadi Sara Bagherieh Yogesh Bahurupi Atif Amin Baig Shumaila Nargus Biswajit Banik Mainak Bardhan Saurav Basu Kavita Batra Nebiyou Simegnew Bayileyegn Fatemeh Bazvand Addisu Shunu Beyene Awoke Masrie Asrat derese devidas S. Bhagat Akshaya Srikanth Bhagavathula Pankaj Bh Medicine & Health University of New South Wales Sydney NSW Australia School of Optometry and Vision Science University of New South Wales Sydney NSW Australia School of Population and Global Health University of Melbourne Carlton VIC Australia Vision and Eye Research Institute Anglia Ruskin University Cambridge UK HelpMeSee Instituto Mexicano de Oftalmologia Santiago de Querétaro Mexico University of Miami Gables FL USA University of Utah Salt Lake City UT USA Chief Medical Office HelpMeSee New York NY USA Mexican Institute of Ophthalmology Queretaro Mexico Department of Ophthalmology Massachusetts Eye and Ear/Shepens Eye Research Institute/Harvard Medical School Boston MA USA Eye Unit MyungSung Christian Medical Center (MCM) Comprehensive Specialized Hospital and MyungSun Medical College Addis Ababa Ethiopia Department of Ophthalmology Addis Ababa University Addis Ababa Ethiopia Sight for Souls Bellevue WA USA Department of Ophthalmology Harvard University Boston MA USA Eye Unit MyungSung Medical College Addis Ababa Ethiopia Addenbrooke’s Hospital Cambridge UK Department of Ophthalmology Cambridge University Hospitals Cambridge UK Federal University of Sao Paolo Sao Paolo SP Brazil University of Calgary Calgary AB Canada Department of Ophthalmology and Visual Sciences Federal University of São Paulo Sao Paulo Brazil School of Medicine Vita-Salute San Raffaele University Milan Italy Department of Ophthalmology IRCCS San Raffaele Scientific Institute Milan Italy Department of Ophthalmology San Raffaele Scientific Institute Milano Italy IRCCS San Raffaele Scientific Institute Vita-Salute University Milan Italy Scientific Institute San Raffaele Hospital Vita-Salute University Milan Italy University of Poitiers Poitiers France CHU de Poitiers Poitiers France Ophthalmology Department CHU de Poitiers (Poitiers University Hospital) Poitiers France Unité 1084 National Institute of Health and Medical Research (INSERM) Poitiers France

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Frontispiece: Quantum Crystallography: Current developments and Future Perspectives

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chemistry – A European Journal 2018年第43期24卷

作者： Alessandro Genoni Lukas Bučinský Nicolas Claiser Julia Contreras-García Birger dittrich Paulina M. dominiak Enrique Espinosa Carlo Gatti Paolo Giannozzi Jean-Michel Gillet dylan Jayatilaka Piero Macchi Anders Ø. Madsen Lou Massa Chérif F. Matta Kenneth M. Merz Jr. philip N. H. Nakashima Holger Ott Ulf Ryde Karlheinz Schwarz Marek Sierka Simon Grabowsky Université de Lorraine CNRS Laboratoire LPCT 1 Boulevard Arago F-57078 Metz France Institute of Physical Chemistry and Chemical Physics Slovak University of Technology FCHPT SUT Radlinského 9 SK-812 37 Bratislava Slovakia Université de Lorraine CNRS Laboratoire CRM2 Boulevard des Aiguillettes BP 70239 F-54506 Vandoeuvre-lès-Nancy France Sorbonne Universités UPMC Université Paris 06 CNRS Laboratoire de Chimie Théorique (LCT) 4 Place Jussieu F-75252 Paris Cedex 05 France Anorganische und Strukturchemie II Heinrich-Heine-Universität Düsseldorf Universitätsstraße 1 40225 Düsseldorf Germany Biological and Chemical Research Centre Department of Chemistry University of Warsaw ul. Żwirki i Wigury 101 02-089 Warszawa Poland CNR-ISTM Istituto di Scienze e Tecnologie Molecolari via Golgi 19 Milano I-20133 Italy Istituto Lombardo Accademia di Scienze e Lettere via Brera 28 20121 Milano Italy Department of Mathematics Computer Science and Physics University of Udine Via delle Scienze 208 I-33100 Udine Italy Structure Properties and Modeling of Solids Laboratory CentraleSupelec Paris-Saclay University 3 rue Joliot-Curie 91191 Gif-sur-Yvette France School of Molecular Sciences University of Western Australia 35 Stirling Highway Perth WA 6009 Australia Department of Chemistry and Biochemistry University of Bern Freiestrasse 3 CH-3012 Bern Switzerland Department of Pharmacy University of Copenhagen Universitetsparken 2 2100 Copenhagen Denmark Hunter College & the Ph.D. Program of the Graduate Center City University of New York New York USA Department of Chemistry and Physics Mount Saint Vincent University Halifax Nova Scotia B3M 2J6 Canada Department of Chemistry Dalhousie University Halifax Nova Scotia B3H 4J3 Canada Department of Chemistry Saint Mary's University Halifax Nova Scotia B3H 3C3 Canada Département de Chimie Université Laval Québec QC G1V 0A6 Canada Department of Chemistry and Department of Biochemistry and Molecular Biology Michigan Stat

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Genome-Wide Association Study in Thai Tsunami Survivors Identified Risk Alleles for Posttraumatic Stress disorder

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Open Journal of Genetics 2015年第2期5卷 43-57页

作者： Nuntika Thavichachart Taisei Mushiroda Thongchai Thavichachart Ongart Charoensook Anchalee Prasansuklab Prathan Rutchatajumroon Sookjaroen Tangwongchai Puangsoi Worakul Buranee Kanchanatawan Siriluck Suppapitiporn Atapol Sughondhabirom Chutima Roomruangwong Wasun Chantratita Atsushi Takahashi Michiaki Kubo Naoyuki Kamatani Yusuke Nakamura Department of Psychiatry Faculty of Medicine Chulalongkorn University Bangkok Thailand Laboratory for Pharmacogenetics RIKEN Center for Genomic Medicine Kanagawa Japan Thailand Center of Excellence for Life Sciences (Public Organization) Ministry of Science and Technology Bangkok Thailand Ph.D. Program in Clinical Biochemistry and Molecular Medicine Department of Clinical Chemistry Faculty of Allied Health Sciences Chulalongkorn University Bangkok Thailand Department of Pathology Faculty of Medicine Mahidol University Bangkok Thailand Laboratory for Statistical Analysis RIKEN Center for Genomic Medicine Kanagawa Japan Laboratory for Genotyping Development RIKEN Center for Genomic Medicine Kanagawa Japan Laboratory of Molecular Medicine Human Genome Center Institute of Medical Science The University of Tokyo Tokyo Japan

Posttraumatic stress disorder (PTSd) is a psychiatric disorder found in individuals afflicted by a traumatic event. Multiple environmental and genetic factors can contribute to PTSd susceptibility. Since it is rare to find members of the same family afflicted by the same catastrophic event, it is not practical to determine PTSd susceptibility genes by a gene linkage analysis. A natural disaster, such as the 2004 Tsunami, provided us with a rare chance for a genetic analysis of PTSd. To identify SNPs associated with PTSd susceptibility, we conducted a genome-association study (GWAS) in Thai-Tsunami survivors. Initial phase of the study with 396 chronic PTSd patients and 457 controls, we identified top ninety SNPs (P -4), which were further assessed in the second phase with 395 chronic PTSd patients and 798 controls. Two SNPs (rs267950 and rs954406), were identified in the second phase, and subjected to fine mapping using a data set from both phases. SNP rs267943 showed the strongest association with PTSd susceptibility and was in complete linkage disequilibrium with SNP rs267950 with P = 6.15 × 10-8, OR = 1.46 and 95% CI = 1.19 - 1.79, reaching genome-wide significance. SNP rs267943 is located on chromosome 5 in the intron of the death-associated protein 1 (dAP1) gene and, when linked to a synthetic promoter, could regulate transcription. To our knowledge, this is the first GWAS for PTSd susceptibility in an Asian population which could provide an important insight into the genetic contribution of PTSd and may lead to new treatment strategies for PTSd.

关键词： death-Associated Protein 1 Gene (dAP1) Genetics Genome-Wide Association Study (GWAS) Posttraumatic Stress disorder (PTSd) Tsunami

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The Synthesis of Stable, Complex Organocesium Tetramic Acids through the Ugi Reaction and Cesium‐Carbonate‐Promoted Cascades

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Angewandte Chemie 2015年第40期127卷

作者： Guillermo Martinez‐Ariza Muhammad Ayaz Sue A. Roberts Walter A. Rabanal‐León Ramiro Arratia‐Pérez Christopher Hulme Department of Pharmacology and Toxicology The University of Arizona BSW Room #351 1041 E. Lowell St. Tucson AZ 85721 (USA) Department of Chemistry and Biochemistry The University of Arizona (USA) Universidad Andrés Bello Facultad de Ciencias Exactas Ph.D. Program in Molecular Physical Chemistry Relativistic Molecular Physics (ReMoPhys) Group Av. República 275 Santiago 8370146 (Chile)

Two structurally unique organocesium carbanionic tetramic acids have been synthesized through expeditious and novel cascade reactions of strategically functionalized Ugi skeletons delivering products with two points of potential diversification. This is the first report of the use of multicomponent reactions and subsequent cascades to access complex, unprecedented organocesium architectures. Moreover, this article also highlights the first use of mild cesium carbonate as a cesium source for the construction of cesium organometallic scaffolds. Relativistic dFT calculations provide an insight into the electronic structure of the reported compounds.

关键词： dieckmann‐Kondensation Kaskadenreaktionen Mehrkomponentenreaktionen Tetramsäuren Ugi‐Reaktion

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Curcumin suppresses doxorubicin-induced epithelial-mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells

Curcumin suppresses doxorubicin-induced epithelial-mesenchym...

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作者： Chen, Wei-Chih Lai, Ying-An Lin, Ying-Chao Ma, Jui-Wen Huang, Li-Fen Yang, Ning-Sun Ho, Chi-Tang Kuo, Sheng-Chu Way, Tzong-der Ph.D. Program for Cancer Biology and Drug Discovery College of Medicine China Medical University Taichung 40402 Taiwan Department of Biological Science and Technology College of Life Sciences China Medical University Taichung 40402 Taiwan Division of Neurosurgery Buddhist Tzu Chi General Hospital Taichung Branch Taichung 427 Taiwan Institute of Biochemistry College of Life Science National Chung Hsing University Taichung 402 Taiwan Graduate School of Biotechnology and Bioengineering Yuan Ze University Taoyuan 320 Taiwan Agricultural Biotechnology Research Center Academia Sinica Taipei 115 Taiwan Department of Food Science Rutgers State University of New Jersey New Brunswick NJ 08901 United States Graduate Institute of Pharmaceutical Chemistry College of Pharmacy China Medical University Taichung 40402 Taiwan Department of Health and Nutrition Biotechnology College of Health Science Asia University Taichung 413 Taiwan

Triple-negative breast cancer (TNBC) is defined by a lack of expression of the estrogen receptor (ER), progesterone receptor (PR), and epidermal growth factor receptor 2 (HER 2). Therefore, targeted therapy agents may not be used, and therapy is largely limited to chemotherapy. doxorubicin treatment consequently acquires undesired malignance characteristics [i.e., epithelial-mesenchymal transition (EMT) and multi-drug resistance]. Our results illustrated that doxorubicin triggered EMT and resulted in the acquisition of a mesenchymal phenotype in TNBC cells. Moreover, we found that transforming growth factor-β (TGF-β) and PI3K/AKT signaling pathways were acquired for doxorubicin-induced EMT. Interestingly, we found that curcumin suppressed doxorubicin-induced EMT. Curcumin reversed doxorubicin-induced morphological changes, inhibited doxorubicin-induced downregulation of E-cadherin expressions, and inhibited doxorubicin-induced upregulation of vimentin expression. We also found that curcumin inhibited doxorubicin-induced EMT by inhibiting the TGF-β and PI3K/AKT signaling pathways. Moreover, curcumin enhanced the antiproliferative effects of doxorubicin in TNBC cells. In summary, our results suggest that doxorubicin in combination with curcumin may be a potential therapy for TNBC. © 2013 American Chemical Society.

关键词： Chemotherapy

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The Broad Institute-Six Years Later

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chemistry & BIOLOGY 2010年第4期17卷 311-312页

作者： McCarthy, Alice Main Text “In June 2003 the scientific and medical communities at MIT Harvard University and its affiliated hospitals and the Whitehead Institute banded together as collaborating partners to form the Eli and Edythe L. Broad Institute based in Cambridge MA. The Broad Institute established with initial funding from a $100 million philanthropic donation from the Los Angeles-based Broad family was primarily viewed as a marriage between the Whitehead Institute's Center for Genome Research (WICGR) and the Harvard Institute of Chemistry and Cell Biology (ICCB). Eli Broad founder and chairman of AIG SunAmerica Inc. explained “the purpose of the Broad Institute is to create a new type of research institute to build on the accomplishments of the human genome project and to move to clinical applications to both prevent and cure diseases.” Every Thursday morning we meet with perhaps 20 faculty members and 100 other researchers to discuss what we're all doing and should be doing next. -David Altschuler This paragraph was written five years ago when the Broad Institute was in its very earliest days as a life science research community (McCarthy 2005). Since that time “the Broad” as it's known has kept true to Eli Broad's vision having attracted a talented group of researchers faculty trainees and professional staff. This 1600 person research community known internally as “Broadies” includes faculty staff and students from throughout the MIT and Harvard biomedical research communities and beyond with collaborations spanning over a hundred private and public institutions in more than 40 countries worldwide. “What is special about the Broad is that we have people from Harvard MIT and the Harvard hospitals come together and work on problems of shared interest that could not be solved in their own individuals labs” explains David Altshuler M.D. Ph.D. Deputy Director and one of the Broad's six core faculty members. “These problems require expertise beyond any one principal investigator and in

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Reduced RNA synthesis levels in isolated mouse liver nuclei following reaction with [(H₂O)(NH₃)5Ru(II)]²⁺

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Molecular and Cellular biochemistry 1989年第1期90卷 37-45页

作者： Marx, Kenneth A. Seery, Christopher Malloy, Patrick Biochemistry Ph.D. Program Department of Chemistry University of Lowell Lowell 01854 MA United States

The goal of this study is to establish the effect of [(H2O)(NH3)5Ru(II)]2+ reaction of nuclei on their RNA transcription levels. This question is important because ammineruthenium compounds share chemical and biologic... 详细信息

The goal of this study is to establish the effect of [(H₂O)(NH3)5Ru(II)]²⁺ reaction of nuclei on their RNA transcription levels. This question is important because ammineruthenium compounds share chemical and biological properties with the chemotherapeutic agent cis-dichlorodiammineplatinum(II) or cisplatin. First we demonstrate that mouse liver nuclei are active in RNA transcription in vitro and characterize the optimum conditions for in vitro transcription. Synthetic rates in the presence of inhibitors actinomycin d and α-Amanitin and measurements of oligo(dT)-cellulose RNA binding levels suggest that all three RNA Polymerases are active in synthesis at about the following percentages-RNA Polymerase I(30%), II(50%) and III(20%). Mouse liver nuclei reacted with [(H₂O)(NH₃)5Ru(II)]²⁺ and then oxidized had (NH₃)₅ Ru(III)³⁺-dNA adduct levels inversely related to total RNA synthetic rates. Oligo(dT) cellulose RNA binding levels did not vary with dNA adduct density. These data suggest that direct dNA lesions rather than [(NH₃)₅Ru(III)]³⁺ effects on other aspects of the transcription system are responsible for the diminished RNA synthesis levels. Ammineruthenium complexes remain desirable candidates for chemotherapeutic agents that may be safely administered in the unreactive ruthenium(III) state and be activated toward dNA binding by reduction in the hypoxic environment of many tumour cells. © 1989 Kluwer Academic Publishers.

关键词： aquopentammineruthenium(II) reaction nuclear RNA transcription oligo(dT) binding levels oxidation to pentammineruthenium(III)

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