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2007 Agent directed Simulation Symposium, AdS 2007

作者： Wakeland, Wayne Macovsky, Louis An, Gary System Science Ph.D. Program Portland State University PortlandOR United States Dynamic BioSystems PortlandOR United States Division of Trauma/Critical Care Northwestern University ChicagoIL United States

ISBN: (纸本)1565553136

The modeling of complex biological systems presents a significant challenge. Central to this challenge is striking a balance between the degree of abstraction required to facilitate analysis and understanding, and the degree of comprehensiveness required for fidelity of the model to its reference-system. It is likely necessary to utilize multiple modeling methods in order to achieve this balance. Our research created a hybrid simulation model by melding an agent-based model of acute local infection with a system dynamics model that reflects key systemic properties. The agent based model was originally developed to simulate global inflammation in response to injury or infection, and has been used to simulate clinical drug trials. The long term objective is to develop models than can be scaled up to represent organ and system level phenomena such as multiple organ failure associated with severe sepsis. The work described in this paper is an initial proof of concept of the ability to combine these two modeling methods into a hybrid model, the type of which will almost certainly be needed to accomplish the ultimate objective of comprehensive in silico research platforms.

关键词： Computational methods

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Comparison of the hydrolysis of polyethylene terephthalate fibers by a hydrolase from Fusarium oxysporum LCH I and Fusarium solani f. sp. pisi

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Biotechnology Journal 2007年第3期2卷 361-364页

作者： Nimchua, Thidarat Punnapayak, Hunsa Zimmermann, Wolfgang Department of Microbiology and Bioprocess Technology Institute of Biochemistry University of Leipzig 04103 Leipzig Germany Biological Science Ph.D. Program Faculty of Science Chulalongkorn University Bangkok Thailand Plant Biomass Utilization Research Unit Department of Botany Chulalongkorn University Bangkok Thailand

The hydrolysis of polyethylene terephthalate (PET) fibers by two fungal hydrolases was investigated. The hydrolase from a newly isolated Fusarium oxysporum strain (LCH 1) was more efficient in releasing terephthalic acid from PET fibers compared to the enzyme from F. solani f. sp. pisi dSM 62420 when equal amounts of p-nitrophenyl butyrate-hydrolyzing activity were employed. PET fabrics treated under the same conditions with the enzyme from F. oxysporum LCH 1 also showed a considerably higher increase in hydrophilicity compared to fabrics treated with the enzyme from F. solani f. sp. pisi dSM 62420. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

关键词： Cutinase Enzymatic hydrolysis Hydrolase Polyethylene terephthalate fibers

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Order-computable sets

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Notre dame Journal of Formal Logic 2007年第3期48卷 317-347页

作者： Hirschfeldt, denis Miller, Russell Podzorov, Sergei Department of Mathematics University of Chicago Chicago IL 60637 5734 S University Ave United States Department of Mathematics Queens College-CUNY Flushing NY 11367 65-30 Kissena Blvd United States Ph.D. Program in Computer Science Graduate Center of CUNY New York NY 10016 365 Fifth Avenue United States Department of Mechanics and Mathematics Novosibirsk State University Novosibirsk 630090 Pirogova St 2 Russian Federation

We give a straightforward computable-model-theoretic definition of a property of Δ02 sets called order-computability. We then prove various results about these sets which suggest that, simple though the definition is... 详细信息

We give a straightforward computable-model-theoretic definition of a property of Δ⁰2 sets called order-computability. We then prove various results about these sets which suggest that, simple though the definition is, the property defies any easy characterization in pure computability theory. The most striking example is the construction of two computably isomorphic ce. sets, one of which is order-computable and the other not. © 2007 University of Notre dame.

关键词： Computable model theory Limitwise-monotonic functions Order-computability

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Tfe Solberg Award

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Naval Engineers Journal 2009年第5期112卷

作者： dr. Roy L. Streit Since 1992 Dr. Streit has focused a significant amount of his energy to assignment problems in acoustic warfare data fusion systems. This work led him to the formulation of the PDD Principle a broadly useful theoretical method that enables the derivation of new classes of discrete-continuous estimation algorithms for solving assignment problems without requiring enumeration and pruning. In recognition of his outstanding work in this area Dr. Streit received the NAVSEA Scientist of the Year Award for 1997. Dr. Streit has also been pursuing avenues for analyzing the loss in broadband detection performance of an acoustic array in the presence of interferences. Because examining all possible separations between the signal and many interferers is infeasible he has proposed a Poisson process model for the number and location (s) of the interferers. In this same time period Dr. Streit has also been investigating issues in environmental modeling and localization by proposing a novel integral method for solving the bearings-only target motion analysis problem which enables a natural heuristic for compensating for mismatch between the model predictions and the real world. Most recently Dr. Streit has proposed the Numerical ACoustic Hull ARray (NACHAR) Project as a revolutionary and ambitious approach to hull array design. Its premise is that optimizing the detection capability of large hull arrays requires the full integration of hull sensor array and beamformer design processes. Because NACHAR crosses an unusual number of technical disciplines it involves researchers from several departments. The diversity of Dr. Streif s technical background makes him uniquely suited to lead the project Dr. Streifs truly impressive scientific achievements are complemented by a noteworthy list of professional activities that accentuate his value to Division Newport and the Navy. He represents the United States in The Technical Cooperation Program Maritime Activities Panel 9 (Sonar Technology) and participates in the Division New

for his significant engineering research and development in sonar array research and acoustic transient signals as set forth in the following

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A Case Study on the Innovation Process from Mission-Oriented Basic Research Stage to Applied Research Stage

A Case Study on the Innovation Process from Mission-Oriented...

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Portland International Conference on Management of Engineering and Technology (PICMET)

作者： Hideki Yoshida Joji Shinohara Tadashi Sasa Eiichi Maruyama Japan Science and Technology Agency (JST) Task Force for Evaluation of Basic Research Programs Tokyo JAPAN National Graduate Institute for Policy Studies (GRIPS) Ph.D. program in Science and Technology Policy Tokyo JAPAN RIKEN Cenier’ for Intellectual Property Strategies Saitama JAPAN

The role of the stage-gate II, interface between mission-oriented basic research and applied research, has been investigated by means of the case studies on typical JST ( Japan science and Technology Agent) projects. The disincentive factors of the breakthrough at the stage-gate II, the patterns of the mission-oriented basic research processes based on this case study, and the success factors of the breakthrough at the stage-gate II are found. Moreover, the stage-gate II is found to be the important indicator of mission-oriented basic research for the innovation process.

关键词： Technological innovation Research and development Intellectual property computer aided software engineering Councils Guidelines Robustness Government International collaboration Statistics

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Epileptic seizure detection

Epileptic seizure detection

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作者： Schuyler, Ronald White, Andrew Staley, Kevin Cios, Krzysztof J. Computational Bioscience Ph.D. Program UCDHSC United States University of Colorado United States American Epilepsy Society Society for Neuroscience United States Department of Neurology Massachusetts General Hospital Harvard Medical School United States Staley Lab. United States University of Colorado at Denver Health Sciences Center United States University of Colorado Bioenergetics Institute United States Data Mining and Bioinformatics Laboratory Turkey Polish Academy of Arts and Sciences Poland Dept. of Computer Science and Engineering University of Colorado at Denver Health Sciences Center P.O. Box 173364 Denver CO 80217-3364 United States

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A Study On Iterative Learning Control With Adjustment Of Learning Interval For Monotone Convergence In The Sense Of Sup-Norm

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Asian Journal of Control 2008年第1期4卷

作者： Kwang-Hyun Park Zeungnam Bien Division of EE Department of EECS Korea Advanced Institute of Science and Technology 373–1 Kusong-dong Yusong-gu Taejon 305–701 Korea. Zeungname Bien:received the B.S. degree in electronics engineering from Seoul National University Seoul Korea in 1969 and the M.S. and Ph.D. degrees in electrical engineering from the University of Iowa Iowa City Iowa U.S.A. in 1972 and 1975 respectively. During 1976–1977 academic years he taught as assistant professor at the Department of Electrical Engineering University of Iowa. Then Dr. Bien joined Korea Advanced Institute of Science and Technology summer 1977 and is now Professor of Control Engineering at the Department of Electrical Engineering and Computer Science KAIST. Dr. Bien was the president of the Korea Fuzzy Logic and Intelligent Systems Society during 1990–1995 and also the general chair of IFSA World Congress 1993 and for FUZZ-IEEE99 respectively. He is currently co-Editor-in-Chief for International Journal of Fuzzy Systems (IJFS) Associate Editor for IEEE Transactions on Fuzzy Systems and a regional editor for the International Journal of Intelligent Automation and Soft Computing. He has been serving as Vice President for IFSA since 1997 and is now Chief Chairman of Institute of Electronics Engineers of Korea and Director of Humanfriendly Welfare Robot System Research Center. His current research interests include intelligent control methods with emphasis on fuzzy logic systems service robotics and rehabilitation engineering and large-scale industrial control systems. Kwang-Hyun Park:received the B.S. M.S. and Ph.D. degrees in electrical engineering and computer science from KAIST Korea in 1994 19997 and 2001 respectively. He is now a researcher at Human-friendly Welfare Robot System Research Center. His research interests include learning control machine learning human-friendly interfaces and service robotics.

It has been found that some huge overshoot in the sense of sup-norm may be observed when typical iterative learning control (ILC) algorithms are applied to LTI systems, even though monotone convergence in the sense of λ-norm is guaranteed. In this paper, a new ILC algorithm with adjustment of learning interval is proposed to resolve such an undesirable phenomenon, and it is shown that the output error can be monotonically converged to zero in the sense of sup-norm when the proposed ILC algorithm is applied. A numerical example is given to show the effectiveness of the proposed algorithm.

关键词： Iterative learning control monotone convergence learning interval sup-norm

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TRACKING CONTROL IN THE PRESENCE OF NONLINEAR dYNAMIC FRICTIONAL EFFECTS: ROBOT EXTENSION

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Asian Journal of Control 2008年第3期1卷

作者： M. Feemster d.M. dawson A. Behal W. dixon Matthew Feemster received the B.S degree in Electrical Engineering from Clemson University Clemson South Carolina in December 1994. Upon graduation he remained at Clemson University and received the M.S. degree in Electrical Engineering in 1997. During this time he also served as a research/teaching assistant. His research work focused on the design and implementation of various nonlinear control algorithms with emphasis on the induction motor and mechanical systems with friction present. He is currently working toward his Ph.D. degree in Electrical Engineering at Clemson University. Darren M. Dawson was born in 1962 in Macon Georgia. He received an Associate Degree in Mathematics from Macon Junior College in 1982 and a B.S. Degree in Electrical Engineering from the Georgia Institute of Technology in 1984. He then worked for Westinghouse as a control engineer from 1985 to 1987. In 1987 he returned to the Georgia Institute of Technology where he received the Ph.D. Degree in Electrical Engineering in March 1990. During this time he also served as a research/teaching assistant. In July 1990 he joined the Electrical and Computer Engineering Department and the Center for Advanced Manufacturing (CAM) at Clemson University where he currently holds the position of Professor. Under the CAM director's supervision he currently leads the Robotics and Manufacturing Automation Laboratory which is jointly operated by the Electrical and Mechanical Engineering departments. His main research interests are in the fields of nonlinear based robust adaptive and learning control with application to electro-mechanical systems including robot manipulators motor drives magnetic bearings flexible cables flexible beams and high-speed transport systems. Aman Behal was born in India in 1973. He received his Masters Degree in Electrical Engineering from Indian Institute of Technology Bombay in 1996. He is currently working towards a Ph.D in Controls and Robotics at Clemson University. His research focuses on the control of no

In this paper, we extend the observer/control strategies previously published in [25] to an n -link, serially connected, direct drive, rigid link, revolute robot operating in the presence of nonlinear friction effects modeled by the Lu-Gre model. In addition, we also present a new adaptive control technique for compensating for the nonlinear parameterizable Stribeck effects. Specifically, an adaptive observer/controller scheme is developed which contains a feedforward approximation of the Stribeck effects. This feedforward approximation is used in a composite controller/observer strategy which forces the average square integral of the position tracking error to an arbitrarily small value. Experimental results are included to illustrate the performance of the proposed controllers.

关键词： Friction compensation nonlinear control

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LANdING AN UNMANNEd AIR VEHICLE: VISION BASEd MOTION ESTIMATION ANd NONLINEAR CONTROL

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Asian Journal of Control 2008年第3期1卷

作者： Omid Shakernia Yi Ma T. John Koo Shankar Sastry Dept. of Electrical Engineering & Computer Science University of California at Berkeley Berkeley CA94720-1774 U.S.A. Tak-Kuen John Koo received the B.Eng. degree in 1992 in Electronic Engineering and the M.Phil. in 1994 in Information Engineering both from the Chinese University of Hong Kong. From 1994 to 1995 he was a graduate student in Signal and Image Processing Institute at the University of Southern California. He is currently a Ph.D. Candidate in Electrical Engineering and Computer Sciences at the University of California at Berkeley. His research interests include nonlinear control theory hybrid systems inertial navigation systems with applications to unmanned aerial vehicles. He received the Distinguished M.Phil. Thesis Award of the Faculty of Engineering The Chinese University of Hong Kong in 1994. He was a consultant of SRI International in 1998. Currently he is the team leader of the Berkeley AeRobot Team and a delegate of The Graduate Assembly University of California at Berkeley. He is a student member of IEEE and SIAM. S. Shankar Sastry received his Ph.D. degree in 1981 from the University of California Berkeley. He was on the faculty of MIT from 1980-82 and Harvard University as a Gordon McKay professor in 1994. He is currently a Professor of Electrical Engineering and Computer Sciences and Bioengineering and Director of the Electronics Research Laboratory at Berkeley. He has held visiting appointments at the Australian National University Canberra the University of Rome Scuola Normale and University of Pisa the CNRS laboratory LAAS in Toulouse (poste rouge) and as a Vinton Hayes Visiting fellow at the Center for Intelligent Control Systems at MIT. His areas of research are nonlinear and adaptive control robotic telesurgery control of hybrid systems and biological motor control. He is a coauthor (with M. Bodson) of “Adaptive Control: Stability Convergence and Robustness Prentice Hall 1989.” and (with R. Murray and Z. Li) of “A Mathematical Introduction to Robotic Manipulati

In this paper, we use computer vision as a feedback sensor in a control loop for landing an unmanned air vehicle (UAV) on a landing pad. The vision problem we address here is then a special case of the classic ego-motion estimation problem since all feature points lie on a planar surface (the landing pad). We study together the discrete and differential versions of the ego-motion estimation, in order to obtain both position and velocity of the UAV relative to the landing pad. After briefly reviewing existing algorithm for the discrete case, we present, in a unified geometric framework, a new estimation scheme for solving the differential case. We further show how the obtained algorithms enable the vision sensor to be placed in the feedback loop as a state observer for landing control. These algorithms are linear, numerically robust, and computationally inexpensive hence suitable for real-time implementation. We present a thorough performance evaluation of the motion estimation algorithms under varying levels of image measurement noise, altitudes of the camera above the landing pad, and different camera motions relative to the landing pad. A landing controller is then designed for a full dynamic model of the UAV. Using geometric nonlinear control theory, the dynamics of the UAV are decoupled into an inner system and outer system. The proposed control scheme is then based on the differential flatness of the outer system. For the overall closed-loop system, conditions are provided under which exponential stability can be guaranteed. In the closed-loop system, the controller is tightly coupled with the vision based state estimation and the only auxiliary sensor are accelerometers for measuring acceleration of the UAV. Finally, we show through simulation results that the designed vision-in-the-loop controller generates stable landing maneuvers even for large levels of image measurement noise. Experiments on a real UAV will be presented in future work.

关键词： Motion estimation computer vision based control unmanned air vehicle differential flatness

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Multi-campus design and implementation of problem-based-learning courses in environmental biotechnology with interdisciplinary learning

Multi-campus design and implementation of problem-based-lear...

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114th Annual ASEE Conference and Exposition, 2007

作者： Hilger, Helene de, Reyes, Francis Los diBiase, Warren Holmes, Len Luster-Teasley, Stephanie Mandjiny, Siva Schimmel, Keith Steck, Todd Wang, Chuang University of North Carolina Charlotte United States Department of Civil and Environmental Engineering University of North Carolina Charlotte United States North Carolina State University United States Department of Civil Construction and Environmental Engineering North Carolina State University United States Department of Science Education University of North Carolina Charlotte United States University of North Carolina Pembroke United States Department of Chemistry University of North Carolina Pembroke United States North Carolina A and T State University United States Pembroke NC United States Department of Chemical Engineering Energy and Environmental Ph.D. Program North Carolina Agricultural and Technical State University Greensboro NC United States Department of Biology University of North Carolina - Charlotte Charlotte NC United States Department of Educational Research University of North Carolina Charlotte United States

No abstract available

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