HCV NS5A is a dimeric phosphoprotein involved in HCV replication. NS5A inhibitors are among direct-acting antivirals (dAA) for HCV therapy. The Y93H mutant of NS5A is resistant to NS5A inhibitors, but the precise mech...
详细信息
The traditional build-and-expand approach is not a viable solution to keep roadway traffic rolling safely, so technological solutions, such as autonomous vehicles (AVs), are favored. AVs have considerable potential to...
详细信息
The traditional build-and-expand approach is not a viable solution to keep roadway traffic rolling safely, so technological solutions, such as autonomous vehicles (AVs), are favored. AVs have considerable potential to increase the carrying capacity of roads, ameliorate the chore of driving, improve safety, provide mobility for those who cannot drive, and help the environment. However, they also raise concerns over whether they are socially responsible, taking into account issues such as fairness, equity, and transparency. Regulatory bodies have focused on AV safety, cybersecurity, privacy, and legal liability issues, but have failed to adequately address social responsibility. Thus, existing AV developers do not have to embed social responsibility factors in their proprietary technology. Adverse bias may therefore occur in the development anddeployment of AV technology. For instance, an artificial intelligence-based pedestrian detection application used in an AV may, in limited lighting conditions, be biased to detect pedestrians who belong to a particular racial demographic more efficiently compared to pedestrians from other racial demographics. Also, AV technologies tend to be costly, with a unique hardware and software setup which may be beyond the reach of lower-income people. In addition, data generated by AVs about their users may be misused by third parties such as corporations, criminals, or even foreign governments. AVs promise to dramatically impact labor markets, as many jobs that involve driving will be made redundant. We argue that the academic institutions, industry firms, and government agencies overseeing AV development anddeployment must act proactively to ensure that AVs serve all anddo not increase the digital divide in our society.
We demonstrate a compact multilayer GaAs–AlAs structure for passive optical edge detection at multiple wavelengths. Through the inverse design of the layer thicknesses, this structure manipulates spatial frequency co...
详细信息
Tantalum silicate (Ta–Si–O) thin film materials have gained significant interest in hybrid renewable energy systems and thin-film resistors due to their exceptional thermal stability and adjustable electrical proper...
详细信息
This study investigated the simultaneous removal of nitrogen andphosphorus from swine wastewater by a magnesium ammonium phosphate crystallization. The precipitation of struvite was determined from swine wastewater, ...
详细信息
Augmented reality (AR) is a technology that instantly merges digital pictures with the real scene. The perspective near-eye display is a key module of AR, through which computer-generated pictures or videos can be dis...
详细信息
Augmented reality (AR) is a technology that instantly merges digital pictures with the real scene. The perspective near-eye display is a key module of AR, through which computer-generated pictures or videos can be displayed in the existing environment. The purpose of this research is to establish the system structure of an augmented reality near-eye display device and to design the off-axis two-piece reflective aspherical mirror. Because AR glasses are wearable and are worn close to the eyes, not only the optical performance of the display but also the clear vision of the user needs to be considered. In this study, an off-axis two-piece reflective aspherical mirror is used as the optical system of the AR for displaying the digital image. The micro-display is placed at the focal point of the optical system to form a digital image, and the horizontal movement of the micro-display along the optical axis is controlled by a precise displacement mechanism so that the patient with uncorrected myopia or hyperopia can see the digital picture and real scene. Because the right and left micro-displays move horizontally independently, the user can see the images on the AR device, which becomes the biggest feature of this study.
Cybersecurity is critical to the digital world's ongoing progress. Whether you are a company owner or a customer, you must be prepared to adapt to new technology, policies, and methods that will aid in the creatio...
Cybersecurity is critical to the digital world's ongoing progress. Whether you are a company owner or a customer, you must be prepared to adapt to new technology, policies, and methods that will aid in the creation of a safer and more secure online environment. As a result, the frequency of exposed network surfaces compels us to invest in more advanced protection measures.
This study proposed a novel extraction method of c-Fos protein regions in dAB(3,3‘-diaminobenzidine)-stained mouse brain slice images using the U-Net model combined with the multi-channelization and $1\times 1$ con...
详细信息
ISBN:
(数字)9798350373332
ISBN:
(纸本)9798350373349
This study proposed a novel extraction method of c-Fos protein regions in dAB(3,3‘-diaminobenzidine)-stained mouse brain slice images using the U-Net model combined with the multi-channelization and
$1\times 1$
convolution techniques. Our U-Net m odel, called
$1\times 1$
conv U-Net, was applied to three dAB- strainedmouse slice images whose resolutions were
$1000\mathrm{x}1000$
pixels. The experimental results demonstrated that the
$1\times 1$
conv U-Net outperformed the conventional U-Net.
We present a new approach for estimating parameters in rational OdE models from given (measured) time series data. In typical existing approaches, an initial guess for the parameter values is made from a given search ...
详细信息
Inflammation is an intrinsic protective mechanism against various forms of cellular injuries in humans;however, its undesired activation results in tissue damage and cell death. The onset of chronic inflammation and o...
详细信息
暂无评论