检索结果-内蒙古大学图书馆

Prior herpes zoster occurrence and high-dose corticosteroids increase herpes zoster risk in rheumatoid arthritis patients receiving janus kinase inhibitors in a retrospective and observational study

引用

Clinical Rheumatology 2024年第8期43卷 2503-2511页

作者： Chen, Po-Ku Chang, Shih-Hsin Chen, Yi-Ming Chen, Hsin-Hua Huang, Po-Hao Huang, Chien-Chung Yeo, Kai-Jieh Lan, Joung-Liang Chen, der-Yuan Rheumatology and Immunology Center China Medical University Hospital No. 2 Yude Road Taichung 40447 Taiwan College of Medicine China Medical University Taichung Taiwan Ph.D. Program in Translational Medicine and Rong Hsing Research Center for Translational Medicine National Chung Hsing University Taichung Taiwan Division of Translational Medicine Department of Medical Research Taichung Veterans General Hospital Taichung Taiwan School of Medicine National Yang-Ming Chiao Tung University Taipei Taiwan Department of Post-Baccalaureate Medicine College of Medicine National Chung Hsing University Taichung Taiwan Department of Industrial Engineering and Enterprise Information Tunghai University Taichung Taiwan Big Data Center National Chung Hsing University Taichung Taiwan Institute of Medicine Chung Shan Medical University Taichung Taiwan

Herpes zoster (HZ) risk is increased in rheumatoid arthritis (RA) patients receiving Janus kinase inhibitors (JAKi) therapy. Identifying and evaluating the risk factors of HZ development in patients receiving JAKi therapy would be clinically helpful. We investigated HZ's incidence rates (IR), identified the risk factors, and further assessed their influence on HZ development in RA patients undergoing JAKi therapy. We retrospectively evaluated 249 RA patients who received JAKi therapy between 2015 and 2023. data regarding clinical characteristics, HZ reactivation, HZ vaccination status, and concomitant medication use were collected. Among 249 JAKi-treated patients, 44 developed new-onset HZ (tofacitinib, 28/142;baricitinib, 6/35;upadacitinib,10/72), with an IR of 5.11/100patient-years. Multivariate analysis revealed significant predictors of HZ development: a long JAKi exposure period, prior HZ or COVId-19 history, and concomitant high-dose corticosteroids use. The interval between JAKi initiation and HZ development was significantly shorter in patients with prior HZ history than in those without (median, 6.5 months versus 33.5 months, p < 0.001), suggesting “biphasic” emergence of HZ. Only one patient who had experienced an HZ episode while receiving JAKi developed recurrent HZ. None of the seventeen patients immunized with the non-live recombinant zoster vaccine developed HZ. Our JAKi-treated patients had elevated HZ risks, a class effect across different JAKi. A long exposure period, prior history of HZ or COVId-19, and concomitant high-dose corticosteroid treatment may further increase the risk. The emergence of HZ shows a biphasic pattern: early HZ development in patients with prior HZ and late development in those without. (Table presented.) © The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR) 2024.

关键词： Herpes zoster Janus kinase inhibitors Rheumatoid arthritis Risk factors Zoster vaccination

来源：评论

学校读者我要写书评

暂无评论

SCUBE2 regulates adherens junction dynamics and vascular barrier function during inflammation

引用

Cardiovascular Research 2024年第13期120卷 1636-1649页

作者： Lin, Yuh-Charn Chang, Ya-Jen Gau, Shiang-Shin Lo, Chun-Min Yang, Ruey-Bing Department of Physiology School of Medicine College of Medicine Taipei Medical University Taipei 110301 Taiwan Institute of Biomedical Sciences Academia Sinica 128 Academia Rd. Sec. 2 Taipei 115201 Taiwan Graduate School of Biostudies Kyoto University Kyoto 6068501 Japan Institute for Integrated Cell-Material Sciences (WPI-iCeMS) Kyoto University Kyoto 6068501 Japan Department of Biomedical Engineering National Yang Ming Chiao Tung University Taipei 112304 Taiwan Biomedical Translation Research Center Academia Sinica 99 Ln. 130 Academia Rd. Sec. 1 Taipei 115201 Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University 250 Wuxing St. Taipei 110301 Taiwan

Aims: SCUBE2 (signal peptide-CUB-epidermal growth factor-like domain-containing protein 2) is a secreted or membrane-bound protein originally identified from endothelial cells (ECs). Our previous work showed that SCUBE2 forms a complex with E-cadherin and stabilizes epithelial adherens junctions (AJs) to promote epithelial phenotypes. However, it remains unclear whether SCUBE2 also interacts with vascular endothelial (VE)-cadherin and modulates EC barrier function. In this study, we investigated whether and how SCUBE2 in ECs regulates vascular barrier maintenance. Methods and results: We showed that SCUBE2 colocalized and interacted with VE-cadherin and VE-protein tyrosine phosphatase (VE-PTP) within EC AJs. Furthermore, SCUBE2 knockdown disrupted EC AJs and increased EC permeability. Expression of EC SCUBE2 was suppressed at both mRNA and protein levels via the nuclear factor-κB signalling pathway in response to pro-inflammatory cytokines or permeability-inducing agents. In line with these findings, EC-specific deletion of Scube2 (EC-KO) in mice impaired baseline barrier function and worsened vascular leakiness of peripheral capillaries after local injection of histamine or vascular endothelial growth factor. EC-KO mice were also sensitive to pulmonary vascular hyperpermeability and leucocyte infiltration in response to acute endotoxin- or influenza virus-induced systemic inflammation. Meanwhile, EC-specific SCUBE2-overexpressing mice were protected from these effects. Molecular studies suggested that SCUBE2 acts as a scaffold molecule enabling VE-PTP to dephosphorylate VE-cadherin, which prevents VE-cadherin internalization and stabilizes EC AJs. As such, loss of SCUBE2 resulted in hyperphosphorylation of VE-cadherin at tyrosine 685, which led to its endocytosis, thus destabilizing EC AJs and reducing barrier function. All of these effects were exacerbated by inflammatory insults. Conclusion: We found that SCUBE2 contributes to vascular integrity by recruiting VE-

关键词： Adherens junctions SCUBE2 Vascular permeability VE-cadherin VE-PTP

来源：评论

学校读者我要写书评

暂无评论

The design of a drone-Assisted System for Large Wildlife Vaccination Shooting Based on AI Image Identification technology

The Design of a Drone-Assisted System for Large Wildlife Vac...

引用

IEEE International Conference on e-Business engineering (ICEBE)

作者： Yao-Yu Tsai Yao-Chuan Tsai Chang-Hsien Tai Chen-Chih Chen Uzu-Kuei Hsu Department of Bio-Industrial Mechatronics Engineering Sustainable Circular Economy R&D Center National Chung Hsing University/National Pingtung University of Science and Technology Pingtung/Taichung Taiwan Department of Bio-Industrial Mechatronics Engineering National Chung Hsing University Taichung Taiwan College of Biomedical Engineering and Technology Tzu Chi University Hualien Taiwan Institute of Wildlife Conservation National Pingtung University of Science and Technology Pingtung Taiwan Program of Artificial Intelligence and Mechatronics National Pingtung University of Science and Technology Pingtung Taiwan

ISBN: (数字)9798350365856

ISBN: (纸本)9798350365863

This study designs a UAV -assisted system integrated with AI image recognition technology to alleviate the difficulty for operators in stabilizing the UAV and accurately administering vaccines. The system uses thermal imaging modules and AI recognition systems to lock onto and track target animals in real-time. Utilizing MAVLink, the UAV adjusts its flight path based on the dynamic behavior of the animals, ensuring that the target remains within shooting range for precise vaccine administration. This technology not only improves the efficiency and accuracy of wildlife vaccination but also significantly reduces the workload on operators, providing a forward-looking solution for wildlife management.

关键词： Accuracy Image recognition Target tracking Target recognition Wildlife Autonomous aerial vehicles Real-time systems Vaccines Artificial intelligence Monitoring

来源：评论

学校读者我要写书评

暂无评论

Oxygen-producing composite dressing activated by photothermal and piezoelectric effects for accelerated healing of infected wounds

引用

Chemical engineering Journal 2023年 476卷

作者： Lai, Yen-Han Roy Barman, Snigdha Ganguly, Anindita Pal, Arnab Yu, Jui-Han Chou, Syun-Hong Huang, E-Wen Lin, Zong-Hong Chen, San-Yuan Department of Materials Science and Engineering National Yang Ming Chiao Tung University Hsinchu30010 Taiwan Institute of Biomedical Engineering National Tsing Hua University Hsinchu30013 Taiwan Department of Biomedical Engineering National Taiwan University Taipei10617 Taiwan Graduate Institute of Biomedical Science China Medical University Hospital Taichung40400 Taiwan School of Dentistry College of Dental Medicine Kaohsiung Medical University Kaohsiung80708 Taiwan International Intercollegiate Ph.D. Program National Tsing Hua University Hsinchu30013 Taiwan

The process of wound healing is often obstructed by the prevalence of bacterial infection at the wound site. Hence, innovative strategies to alleviate infection is extremely necessary to realize effective wound recovery in a timely manner. Here, we report a self-activated composite dressing consisting of piezoelectric and photothermal functional layers for combating wound infection and provide the desired treatment. The synergistic dressing is functionalized with piezoelectric Poly-L-lactic acid (PLLA) which under the effect of ultrasound irradiation controllably generates reactive oxygen species (ROS) for antibacterial activity, thus facilitating the dressing to inhibit the growth of bacteria at the wound bed. Further, the dressing is modified with calcium peroxide (CaO2) which can effectively convert the generated ROS into molecular oxygen (O2) in presence of catalase enzyme for treating chronic hypoxia in the infected wounds. The sustained generation of O2 by the wound dressing augmented the cell proliferation, migration and tissue regeneration aiding in wound healing. By combining the inherent photothermal activity of reduced graphene oxide (rGO), the synergistic dressing under NIR irradiation enhanced the wound recovery by upregulating the heat shock protein 90 (Hsp90) secretion owing to the heat generation on the wounds. The results obtained demonstrate that the self-triggered multifunctional wound dressing is a promising candidate for clinical treatment of infected wounds with a user-friendly interface. © 2023 Elsevier B.V.

关键词： Ultrasonics

来源：评论

学校读者我要写书评

暂无评论

Crystal structure-controlled synthesis of NiMoO4/NiO hierarchical microspheres for high-performance supercapacitors and photocatalysts

引用

Journal of Energy Storage 2024年 97卷

作者： Lee, Kuen-Chan Huang, Jen-Hsien Wu, Yen-Ju Wang, Kuan-Syun Cho, Er-Chieh Hsu, Shih-Chieh Liu, Ting-Yu Department of Science Education National Taipei University of Education No. 134 Sec. 2 Heping E. Road Da-an District Taipei City106 Taiwan Ph.D. Program in Medical Neuroscience College of Medical Science and Technology Taipei Medical University 250 Wuxing Street Taipei City110 Taiwan Department of Green Material Technology Green Technology Research Institute CPC Corporation No.2 Zuonan Rd. Nanzi District Kaohsiung City81126 Taiwan 1-2-1 Sengen Tsukuba Ibaraki305-0047 Japan Department of Materials Engineering Ming Chi University of Technology New Taipei City243303 Taiwan School of Pharmacy College of Pharmacy Taipei Medical University 250 Wuxing Street Taipei City110 Taiwan Department of Chemical and Materials Engineering Tamkang University No. 151 Yingzhuan Road Tamsui District New Taipei City25137 Taiwan Department of Chemical Engineering and Materials Science Yuan Ze University Taoyuan City32003 Taiwan College of Engineering & Center for Sustainability and Energy Technologies Chang Gung University Taoyuan33302 Taiwan

Global environmental challenges and energy crises have driven researchers to develop multifunctional and highly efficient nanomaterials. This study presents dual-functional NiMoO4 (NMO)/NiO hierarchical microspheres that can serve as supercapacitors and photocatalysts prepared using a microwave-assisted hydrothermal method. The α- and β-phase contents of NMO can be regulated by controlling the post-annealing temperature and ph value of the precursor solution. The as-prepared NMO/NiO nanocomposites exhibited dual Faradaic redox reactions attributed to NMO and NiO, leading to remarkable supercapacitor performance. In addition, the constructed heterojunction between NMO and NiO also improved charge separation, leading to excellent photocatalytic capability. Based on the results, NMO with a higher β-phase content showed better supercapacitive and photocatalytic performance owing to its higher conductivity. The optimal NMO/NiO composite displayed a specific capacitance of 943 F g−1 at 1 A/g and excellent cycling stability, with 83.1 % retention at 5 A/g after 4000 cycles. Additionally, it demonstrated an outstanding photocatalytic capability for the degradation of methylene blue (MB), achieving a rate constant of (0.0113 min−1). © 2024 Elsevier Ltd

关键词： Supercapacitor

来源：评论

学校读者我要写书评

暂无评论

Size-controlled immunomodulatory and vaccine adjuvant potentials of self-assembled hyaluronic acid nanoparticles: Activation and recruitment of immune cells

引用

International Journal of Biological Macromolecules 2025年 314卷 144265页

作者： Chu, Po-Cheng Birhan, Yihenew Simegniew Zhao, Min-Han Syu, Wei-Jhe Chen, Po-Yen Lin, Yu-Tsen Lai, Ping-Shan Department of Chemistry National Chung Hsing University Taichung402 Taiwan Basic Research and Development Department Powin Biomedical Co. Ltd. Taichung428 Taiwan Department of Chemistry College of Natural and Computational Sciences Debre Markos University P.O. Box 269 Debre Markos Ethiopia Department of Chemical and Biomolecular Engineering University of Maryland College Park MD20742 United States Ph.D. Program in Tissue Engineering and Regenerative Medicine National Chung Hsing University Taichung402 Taiwan

Immunotherapy has paramount importance in treating chronic immune diseases, and vaccine development. Hyaluronic acid (HA) has been shown to elicit molecular weight-related distinct immune responses. Nonetheless, the particle size-dependent immunomodulatory effects of hyaluronic acid nanoparticles (HA-NPs) remain blurred. Thus, the present study aimed at investigating the effect of polymer configuration and particle size of HA-NPs assembled from HA36K-OdA and HA360k-OdA analogs in modulating macrophage-related immune activities. In the in vitro experiments, HA-NPs of HA36k-OdA analogs garnered significantly enhanced nitrite production with low interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) secretion in macrophages. Furthermore, smaller (36k-OdA NPs activated Cd11b+ cells whereas a ∼ 130 nm HA36k-OdA15 NPs preferentially induced Cd11c+ cells in vivo, indicating the influence of particle size on the antigen-presenting cells (APCs) recruitment. Interestingly, self-assembled HA36k-OdA15 NPs without ovalbumin (OVA) activated immature dendritic cells (dCs) and augmented their migration toward the lymph nodes (LNs). Notably, HA36k-OdA15-activated macrophages behaved like M1 phenotype macrophages. Overall, our findings garnered valuable insights about the design and application of HA-NPs for modulating the immune responses in nanoscale materials-based immunotherapy. © 2025

关键词： Macrophages

来源：评论

学校读者我要写书评

暂无评论

Enhanced electrochemical detection of tartrazine in beverages and liquid soap via nickel phosph.d.-adorned functionalized carbon nanofibers

引用

Journal of the Taiwan Institute of Chemical Engineers 2024年 157卷

作者： Gokulkumar, Kumar Huang, Song-Jeng Kogularasu, Sakthivel Aljuwayid, Ahmed M. Maheshwaran, Selvarasu Govindasamy, Mani Department of Mechanical Engineering National Taiwan University of Science and Technology Taipei City106335 Taiwan Super micro mass research and technology center Cheng Shiu University Kaohsiung833301 Taiwan Center for Environmental Toxin and Emerging-Contaminant Research Cheng Shiu University Kaohsiung833301 Taiwan Department of Chemistry College of Science King Saud University P. O. Box 2455 Riyadh11451 Saudi Arabia Department of Aeronautics and Astronautics National Cheng Kung University Tainan701 Taiwan International Ph.D. Program In Innovative Technology of Biomedical Engineering and Medical Devices Ming Chi University of Technology New Taipei City243303 Taiwan Tamil Nadu Chennai602105 India

Background: Tartrazine (TAT) is a widely used food colorant dye, offering an orange-yellow hue in various products such as foods, cosmetics, and pharmaceuticals. despite its popularity, TAT is banned in several countries due to its potential health risks, including respiratory issues, migraines, and skin allergies. Moreover, TAT is linked with adverse effects on human physiology, including mutagenicity, biliary cirrhosis, changes in liver and kidney functions, and neurodegeneration at varying doses. Consequently, the detection of this food additive is crucial for safeguarding human health and protecting aquatic organisms. Methods: In this study, a novel sensor was developed for the detection of TAT, utilizing a composite material made from nickel phosph.d. decorated with functionalized carbon nanofiber (Ni2P@f-CNF). The Ni2P@f-CNF was synthesized and characterized through several techniques, including X-ray diffraction, X-ray photoelectron spectroscopy, field emission-scanning electron microscopy, and elemental mapping. The composite was then integrated with a glassy carbon electrode to create a sensor. The sensor's performance was evaluated in terms of detection limit, linear range, selectivity, sensitivity, reproducibility, repeatability, and long-term stability. Main Findings: The developed Ni2P@f-CNF composite sensor displayed a lower detection limit of 0.011 µM and a broad linear range from 0.01 to 1875 µM. Its selectivity and sensitivity were exceptional, primarily due to the catalytic activity of the Ni2P@f-CNF composite towards TAT. The sensor also demonstrated excellent reproducibility, repeatability, and notable long-term stability. Importantly, when applied in real-world scenarios, the sensor successfully detected TAT in soft drink and liquid soap samples, yielding high recovery rates between 97.45 % to 99.37 % and 98.26 % to 99.01 %, respectively, underscoring its potential applicability in practical settings. © 2024 Taiwan Institute of Chemical Engineer

关键词： Nickel compounds

来源：评论

学校读者我要写书评

暂无评论

An Improvement of A Robust Authentication Protocol for Multi-server Architecture Using Elliptic Curve Cryptography

引用

International Journal of Network Security 2024年第4期26卷 713-718页

作者： Hwang, Min-Shiang Li, Hou-Wen Yang, Cheng-Ying Department of Computer Science & Information Engineering Asia University Taiwan Fintech and Blockchain Research Center Asia University Taiwan The Ph.D. Program in Artificial Intelligence Asia University Taiwan 500 Lioufeng Rd. Wufeng Taichung Taichung41354 Taiwan Department of Medical Research China Medical University Hospital China Medical University Taichung40402 Taiwan Department of Computer Science University of Taipei Taipei Taiwan

The user authentication scheme of the multi-server architecture is mainly that the user only needs to register once to access many distributed servers. This architecture solves the problem of repeated multiple registrations in many servers and can provide a scalable solution. Recently, Zhang et al. proposed a secure, robust remote user authentication scheme for multi-servers using elliptic curve cryptography. However, their proposed scheme can solve many severe flaws and authenticate messages while keeping users anonymous. However, we will show that their scheme couldn’t withstand online password-guessing with a user’s smart card attack and a denial of service attack. This article proposes improving user authentication protocol against these vulnerabilities in Zhang et al.’s protocol. © (2024) All rights reserved.

关键词： Smart cards

来源：评论

学校读者我要写书评

暂无评论

Research and Innovation In Next Generation Security and Privacy In Industry 5.0 Iot

Research and Innovation In Next Generation Security and Priv...

引用

International Conference on Contemporary Computing and Informatics (IC3I)

作者： Geeta S. Navale Ravikiran Madala Manjunath Managuli N. Jayalakshmi G. Kadiravan Ruchira Rawat Department of Computer Engineering Sinhgad Institute of Technology and Science Pune Maharashtra India Network and Data Center Engineer Ph.D Information Technology University of Cumberlands Durham North Carolina United States Department of Electronics and Communication Engineering KLS Gogte Institute of Technology Belegavi Karnataka India Master of Computer Applications PSNA College of Engineering and Technology Dindigul Tamilnadu India Department of Computer Science and Information Technology KL Deemed to be University Andhra Pradsh India Department of Computer Science and Engineering Graphic Era Deemed to be University Dehradun Uttrakhand India

The objective of the newest manufacturing paradigm, known as “Industry 5.0,” is to combine human intelligence with cutting-edge technology like the Internet of Things (IoT), artificial intelligence (AI), and robots to develop production systems that are incredibly effective and adaptable. But as we rely more on these technologies, we face additional privacy and security issues that might affect how dependable and trustworthy these systems are. In this report, we examine the most recent advancements in security and privacy for Industry 5.0 IoT and pinpoint the newest trends, obstacles, and possibilities. We also cover how these changes may affect manufacturing in the future and provide advice to scholars, practitioners, and policymakers.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Ginkgolide B facilitates muscle regeneration via rejuvenating osteocalcin-mediated bone-to-muscle modulation in aged mice

引用

Journal of cachexia, sarcopenia and muscle 2023年第3期14卷 1349-1364页

作者： Belle Yu-Hsuan Wang Yi-Fan Chen Allen Wei-Ting Hsiao Wan-Jing Chen Chien-Wei Lee Oscar Kuang-Sheng Lee Musculoskeletal Research Laboratory SH Ho Scoliosis Research Laboratory Department of Orthopaedics and Traumatology Faculty of Medicine The Chinese University of Hong Kong Hong Kong. Center for Neuromusculoskeletal Restorative Medicine CUHK InnoHK Centres Hong Kong Science Park Hong Kong. The Ph.D. Program for Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei Taiwan. Graduate Institute of Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei Taiwan. International Ph.D. Program for Translational Science College of Medical Science and Technology Taipei Medical University Taipei Taiwan. Master Program in Clinical Genomics and Proteomics School of Pharmacy Taipei Medical University Taipei Taiwan. Department of Orthopaedics and Traumatology Faculty of Medicine Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong. Center for Translational Genomics & Regenerative Medicine Research China Medical University Hospital China Medical University Taichung Taiwan. Department of Biomedical Engineering China Medical University Taichung Taiwan. Department of Orthopedics China Medical University Hospital Taichung Taiwan. Institute of Clinical Medicine National Yang Ming Chiao Tung University Taipei Taiwan.

BACKGROUNd:The progressive deterioration of tissue-tissue crosstalk with aging causes a striking impairment of tissue homeostasis and functionality, particularly in the musculoskeletal system. Rejuvenation of the systemic and local milieu via interventions such as heterochronic parabiosis and exercise has been reported to improve musculoskeletal homeostasis in aged organisms. We have shown that Ginkgolide B (GB), a small molecule from Ginkgo biloba, improves bone homeostasis in aged mice by restoring local and systemic communication, implying a potential for maintaining skeletal muscle homeostasis and enhancing regeneration. In this study, we investigated the therapeutic efficacy of GB on skeletal muscle regeneration in aged mice. METHOdS:Muscle injury models were established by barium chloride induction into the hind limb of 20-month-old mice (aged mice) and into C2C12-derived myotubes. Therapeutic efficacy of daily administrated GB (12 mg/kg body weight) and osteocalcin (50 μg/kg body weight) on muscle regeneration was assessed by histochemical staining, gene expression, flow cytometry, ex vivo muscle function test and rotarod test. RNA sequencing was used to explore the mechanism of GB on muscle regeneration, with subsequent in vitro and in vivo experiments validating these findings. RESULTS:GB administration in aged mice improved muscle regeneration (muscle mass, P = 0.0374; myofiber number/field, P = 0.0001; centre nucleus, embryonic myosin heavy chain-positive myofiber area, P = 0.0144), facilitated the recovery of muscle contractile properties (tetanic force, P = 0.0002; twitch force, P = 0.0005) and exercise performance (rotarod performance, P = 0.002), and reduced muscular fibrosis (collagen deposition, P < 0.0001) and inflammation (macrophage infiltration, P = 0.03). GB reversed the aging-related decrease in the expression of osteocalcin (P < 0.0001), an osteoblast-specific hormone, to promote muscle regeneration. Exogenous osteocalcin supplementation was

关键词： Ginkgolide B aging osteocalcin rejuvenation skeletal muscle regeneration

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：