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Analytical Maximum Energy Product (BH)max Model for Rare-Earth-Free Magnets: Core-Shell Nanostructure

IEEE Transactions on Magnetics 2025年

作者： Hong, Yang-Ki Bae, Seok Park, Jihoon Choi, Minyeong Lee, Won-Cheol Yeo, Chang-dong Wahed, Md Abdul Lee, Kisuk Yim-Choi, Haein Lee, Woo-Young Department of Electrical and Computer Engineering Materials Science Ph.D. Program The University of Alabama TuscaloosaAL35487 United States LG Innotek R&D Division Seoul Korea Republic of Korea Institute of Materials Science Gyeongsangnam-Do Changwon Korea Republic of Hyundai Motors Company R&D Division Namyang Gyeonggi-Do Korea Republic of RF Development Team S.LSI Samsung Electronics Gyeonggi-Do Hwaseong18448 Korea Republic of Texas Tech University Department of Mechanical Engineering TX79409 United States Ulsan National Institute of Science and Technology Department of Materials Science and Engineering Gyeongsangnam-Do Ulsan Korea Republic of SookMyung Women’s University Department of Applied Physics Seoul Korea Republic of Yonsei University Department of Materials Science and Engineering Seoul Korea Republic of

This paper presents an analytical model for the maximum energy product ((BH)max) in core-shell structured magnetic exchange-coupled nanomagnets. The model was validated by comparing its results to the (BH)max from core-shell magnets reported in the literature. This approach can serve as a universal model for designing core-shell magnets that achieve the desired (BH)max. The (BH)max was determined under two distinct nucleation field (HN) conditions: HN ≤ Mr/2 and HN ≥ Mr/2, where Mr is the remanent magnetization. Additionally, two different values of magnetic hysteresis loop squareness (SQ = Mr/MS) were used: 1.0 and 0.7. The soft magnetic shell’s remanent magnetic flux density (Br) ranged from 0.7 to 2.2 T, while the core diameter (dh) varied between 50 and 250 nm in this (BH)max model. The LTP (low-temperature phase) MnBi-core/soft-shell nanomagnet can achieve a (BH)max of 40 MGOe at a Br of 1.6 T, with a shell thickness (δS) of 40 nm, a dh of 250 nm, and a volume fraction of the hard-core (fh) of 0.43. The (BH)max of the hexaferrite (SrFe12O19)/soft-shell (1.9 T) nanomagnet can be improved from 5.8 (single hexaferrite phase) to 20 MGOe. This approach achieves the desired (BH)max of the rare-earth-free permanent magnet, thereby tackling issues related to rare-earth mineral security and unstable supply chains. © 1965-2012 IEEE.

关键词： Permanent magnets

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Integrating subvolume dose and myocardial perfusion imaging parameters to assess the impact of radiation therapy on heart function in breast cancer patients: A comparative analysis between left- and right-sided breast cancer

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Thoracic Cancer 2023年第26期14卷 2696-2706页

作者： Wang, Shan-Ying Tsai, Wei-Ta Lin, Kuan-Heng Yu, Chih-Wei Yang, Shu-Ya Shueng, Pei-Wei Wu, Yen-Wen Hsu, Chen-Xiong Wu, Tung-Hsin Department of Biomedical Imaging and Radiological Sciences National Yang Ming Chiao Tung University Taipei Taiwan Department of Nuclear Medicine Far Eastern Memorial Hospital New Taipei City Taiwan Department of Radiation Oncology Dalin Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation Chiayi Taiwan Division of Radiation Oncology Department of Radiology Far Eastern Memorial Hospital New Taipei City Taiwan Industrial Ph.D. Program of Biomedical Science and Engineering National Yang Ming Chiao Tung University Taipei Taiwan Department of Radiation Oncology China Medical University Hsinchu Hospital Zhubei City Taiwan Institute of Nuclear Engineering and Science National Tsing Hua University Hsinchu City Taiwan Department of Nuclear Medicine Cheng Hsin General Hospital Taipei Taiwan School of Medicine College of Medicine National Yang Ming Chiao Tung University Taipei Taiwan Division of Cardiology Cardiovascular Medical Center Far Eastern Memorial Hospital New Taipei City Taiwan

Background: This study aimed to utilize an innovative method of integrating the 20 subvolume dose of left ventricle and the Tl-201 single photon emission computed tomography (SPECT) with myocardial perfusion imaging (MPI) parameters in patients with left- and right-sided breast cancer after radiation therapy. Methods: Female patients with breast cancer underwent SPECT MPI before commencing radiotherapy and 12 months later were enrolled from January 2014 to december 2018. The images of CT simulation and SPECT MPI were integrated into the treatment planning system. The differences of doses and parameters of MPI in all cardiac subvolumes between left- and right-sided breast cancer patients were analyzed. Results: Patients with left-sided breast cancer (n = 61) received a higher radiation dose to the heart, left ventricular, and its territories and subvolumes, compared to patients with right-sided breast cancer (n = 19). The 20-segment analysis also showed statistically significant disparities in the average radiation doses received by the two groups. In different coronary artery territories, the end-diastolic perfusion and end-systolic perfusion showed a decrease in both sides, with no significant differences. However, the wall motion and wall thickening showed a significant decline in subregions within the left- and right-sided coronary artery territories. Conclusion: This study demonstrates an innovative integrated method combining the left ventricular 20 regional doses with SPECT MPI which shows that left-sided breast cancer patients receive a higher subvolume dose than right-sided breast cancer patients. Further research is needed to confirm the potential impact on heart function after radiotherapy on both sides. © 2023 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

关键词： myocardial perfusion imaging radiation therapy subvolume dose

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Fabrication of Solvent-Free PCL/β-TCP Composite Fiber for 3d Printing: physiochemical and Biological Investigation

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Polymers 2023年第6期15卷 1391-1391页

作者： Ngo, Sin Ting Lee, Wei-Fang Wu, Yi-Fan Salamanca, Eisner Aung, Lwin Moe Chao, Yan-Qiao Tsao, Ting-Chia Hseuh, Hao-Wen Lee, Yi-Huan Wang, Ching-Chiung Chang, Wei-Jen Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei110 Taiwan School of Dental Technology College of Oral Medicine Taipei Medical University Taipei110 Taiwan School of Dentistry College of Oral Medicine Taipei Medical University Taipei110 Taiwan Department of Molecular Science and Engineering National Taipei University of Technology Taipei106 Taiwan School of Pharmacy College of Pharmacy Taipei Medical University Taipei110 Taiwan Traditional Herbal Medicine Research Center Taipei Medical University Hospital Taipei110 Taiwan Dental Department Taipei Medical University Shuang Ho Hospital New Taipei235 Taiwan

Manufacturing three-dimensional (3d) objects with polymers/bioceramic composite materials has been investigated in recent years. In this study, we manufactured and evaluated solvent-free polycaprolactone (PCL) and beta-tricalcium phosphate (β-TCP) composite fiber as a scaffold material for 3d printing. To investigate the optimal ratio of feedstock material for 3d printing, the physical and biological characteristics of four different ratios of β-TCP compounds mixed with PCL were investigated. PCL/β-TCP ratios of 0 wt.%, 10 wt.%, 20 wt.%, and 30 wt.% were fabricated, with PCL melted at 65 °C and blended with β-TCP with no solvent added during the fabrication process. Electron microscopy revealed an even distribution of β-TCP in the PCL fibers, while Fourier transform infrared spectroscopy demonstrated that the biomaterial compounds remained intact after the heating and manufacturing process. In addition, adding 20% β-TCP into the PCL/β-TCP mixture significantly increased hardness and Young’s Modulus by 10% and 26.5%, respectively, suggesting that PCL-20 has better resistance to deformation under load. Cell viability, alkaline phosphatase (ALPase) activity, osteogenic gene expression, and mineralization were also observed to increase according to the amount of β-TCP added. Cell viability and ALPase activity were 20% higher with PCL-30, while upregulation for osteoblast-related gene expression was better with PCL-20. In conclusion, PCL-20 and PCL-30 fibers fabricated without solvent exhibited excellent mechanical properties, high biocompatibility, and high osteogenic ability, making them promising materials for 3d printing customized bone scaffolds promptly, sustainably, and cost-effectively. © 2023 by the authors.

关键词： Bone

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Enhancement of Channel Capacity in 5G Ultra dense Network-UdN

Enhancement of Channel Capacity in 5G Ultra Dense Network-UD...

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International Conference on Edge Computing and Applications (ICECAA)

作者： Ritesh Rastogi T. Shanthi Pramod Kumar Naik M. Sahaya Sheela A.K Mishra Nandhini T J Department of IT and CS M.Tech(Int) Noida Institute of Engineering and Technology Delhi India Department of ECE Paavai Engineering College Chennai India Departmeny of Computer Science Engineering Dayananda Sagar University Bangalore India Department of ECE Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and Technology Chennai India Math Unit Foundation Program Dhofar University Salalah Oman Saveetha School of Engineering Saveetha Institute of Medical and Technical Science - (SIMATS) Chennai India

A 5G ultra dense network architecture makes use of a high density of micro cell base stations to provide increased coverage, capacity, and performance for 5G communication systems. This is accomplished by the utilization of a very densely packed network. A 5G ultradense network is another name for this particular category of network. Ultradense networks are built to overcome the limitations of ordinary cellular networks. This is accomplished by increasing the number of base stations that are located inside a given area. This is performed by reducing the coverage area provided by each base station, which ultimately leads to an increase in the capacity of the entire network. The maximum data rate or capacity that may be obtained through a certain wireless channel is referred to as the “channel capacity” in a 5G ultradense network, when the phrase “channel capacity” is used. One possibility is that this represents the maximum quantity of data that can be transmitted across the channel. These criteria, which represent the capabilities of the channel, can be used to evaluate the performance of channels and equipment on 5G networks. This article presents for further research a model for improving the channel capacity of the 5G ultradense network. The model can be found at the end of the article. This change will result in an increase in both the usefulness of the channel and the amount of bandwidth that it consumes; both of these aspects will improve. The fact that it uses a very small quantity of energy and power in compared to other methods is the major trait that sets it apart from other methods. This technology is superior to others in terms of both the amount of data it can communicate and the amount of electricity it consumes in the process.

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deep Unsupervised Learning for Biomedical Image Translation from Harmonic Generation Microscopy Image to H&E-stained Image

Deep Unsupervised Learning for Biomedical Image Translation ...

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Conference on Lasers and Electro-Optics (CLEO)

作者： Wei-Ju Chen En-Yu Liao Tsung-Ming Tai Yi-Hua Liao Chi-Kuang Sun Cheng-Kuang Lee Simon See Hung-Wen Chen International Intercollegiate Ph.D. Program National Tsing Hua University Hsinchu Taiwan Department of Electrical Engineering and Graduate Institute of Photonics and Optoelectronics National Taiwan University Taipei Taiwan NVIDIA AI Technology Center NVIDIA Taipei Taiwan Department of Dermatology National Taiwan University Hospital and College of Medicine National Taiwan University Taipei Taiwan Institute of Photonics Technologies National Tsing Hua University Hsinchu Taiwan

This work proposes an unsupervised deep learning-based image translation from Harmonic generation microscopy (HGM) to widely used H&E-stained images. The proposed methodology is promising and hopefully will facili... 详细信息

ISBN: (纸本)9781957171258

关键词： Harmonic generation Image analysis Image stacking Second harmonic generation Third harmonic generation Three dimensional imaging

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YAP-regulated type II alveolar epithelial cell differentiation mediated by human umbilical cord-derived mesenchymal stem cells in acute respiratory distress syndrome

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Biomedicine and pharmacotherapy 2023年第1期159卷 114302-114302页

作者： Chen, Xiao-Yue Chen, Kuan-Yuan Feng, Po-Hao Lee, Kang-Yun Fang, Yu-Ting Chen, You-Yin Lo, Yu-Chun Bhavsar, Pankaj K. Chung, Kian Fan Chuang, Hsiao-Chi Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei Taiwan School of Respiratory Therapy College of Medicine Taipei Medical University Taipei Taiwan National Heart and Lung Institute Imperial College London London United Kingdom Division of Pulmonary Medicine Department of Internal Medicine Shuang Ho Hospital Taipei Medical University New Taipei City Taiwan Division of Pulmonary Medicine Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei Taiwan Department of Biomedical Engineering National Yang Ming Chiao Tung University Taipei Taiwan The Ph.D. Program for Neural Regenerative Medicine College of Medical Science and Technology Taipei Medical University Taipei Taiwan Industrial Ph.D. Program of Biomedical Science and Engineering National Yang Ming Chiao Tung University Taipei Taiwan Cell Physiology and Molecular Image Research Center Wan Fang Hospital Taipei Medical University Taipei Taiwan

Acute respiratory distress syndrome (ARdS) contributes to higher mortality worldwide. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have immunomodulatory and regenerative potential. However, the effects of hUC-MSCs as an ARdS treatment remain unclear. We investigated the role of hUC-MSCs in the differentiation of type II alveolar epithelial cells (AECII) by regulating Yes-associated protein (YAP) in ARdS. Male C57BL/6JNarl mice were intratracheally (i.t.) administered lipopolysaccharide (LPS) to induce an ARdS model, followed by a single intravenous (i.v.) dose of hUC-MSCs. hUC-MSCs improved pulmonary function, decreased inflammation on day 3, and mitigated lung injury by reducing the lung injury score and increasing lung aeration (%) in mice on day 7 (p < 0.05). hUC-MSCs inactivated YAP on AECII and facilitated cell differentiation by decreasing Pro-surfactant protein C (Pro-SPC) and galectin 3 (LGALS3) while increasing podoplanin (T1α) in lungs of mice (p < 0.05). In AECII MLE-12 cells, both coculture with hUC-MSCs after LPS exposure and the YAP inhibitor, verteporfin, reduced Pro-SPC and LGALS3, whereas the YAP inhibitor increased T1α expression (p < 0.05). In conclusion, hUC-MSCs ameliorated lung injury of ARdS and regulated YAP to facilitate AECII differentiation. © 2023 The Authors

关键词： Alveoli Inflammation Pneumocytes Regeneration Stem cells

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Cold atmospheric plasma-enabled platelet vesicle incorporated iron oxide nano-propellers for thrombolysis

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Materials Today Bio 2023年 23卷 100876页

作者： Jheng, Pei-Ru Chiang, Chia-Che Kang, Jiunn-Horng Fan, Yu-Jui Wu, Kevin C.-W. Chen, Yan-Ting Liang, Jia-Wei Bolouki, Nima Lee, Jyh-Wei Hsieh, Jang-Hsing Chuang, Er-Yuan Graduate Institute of Nanomedicine and Medical Engineering Graduate Institute of Biomedical Materials and Tissue Engineering Institute of Biomedical Optomechatronics International Ph.D. Program in Biomedical Engineering School of Biomedical Engineering College of Biomedical Engineering Professional Master Program in Artificial Intelligence in Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Department of Physical Medicine and Rehabilitation Taipei Medical University Hospital Taipei Taiwan Institute of Biomedical Engineering & Nanomedicine National Health Research Institute Keyan Road Zhunan Miaoli City350 Taiwan Department of Chemical Engineering National Taiwan University No.1 Sec. 4 Roosevelt Rd Taipei10617 Taiwan Department of Plasma Physics and Technology Faculty of Science Masaryk University Brno Czech Republic Center for Plasma and Thin Film Technologies Ming Chi University of Technology New Taipei City Taiwan Department of Materials Engineering Ming Chi University of Technology New Taipei City Taiwan Cell Physiology and Molecular Image Research Center Taipei Medical University-Wan Fang Hospital Taipei11696 Taiwan

A new approach to treating vascular blockages has been developed to overcome the limitations of current thrombolytic therapies. This approach involves biosafety and multimodal plasma-derived theranostic platelet vesicle incorporating iron oxide constructed nano-propellers platformed technology that possesses fluorescent and magnetic features and manifold thrombus targeting modes. The platform is capable of being guided and visualized remotely to specifically target thrombi, and it can be activated using near-infrared phototherapy along with an actuated magnet for magnetotherapy. In a murine model of thrombus lesion, this proposed multimodal approach showed an approximately 80 % reduction in thrombus residues. Moreover, the new strategy not only improves thrombolysis but also boosts the rate of lysis, making it a promising candidate for time-sensitive thrombolytic therapy. © 2023 The Authors

关键词： Infrared devices

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Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery

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Nucleic Acids Research 2023年第19期51卷 10768-10781页

作者： Liu, Ze Wang, Justin Shi, Yi Yee, Brian A Terrey, Markus Zhang, Qian Lee, Jenq-Chang Lin, Kuo-I Wang, Andrew H-J Ackerman, Susan L Yeo, Gene W Cui, Haissi Yang, Xiang-Lei Department of Molecular Medicine Scripps Research Institute La Jolla 92037 CA United States Department of Biochemistry School of Medicine Nankai University Tianjin China Department of Cellular and Molecular Medicine University of California San Diego La Jolla 92093 CA United States Howard Hughes Medical Institute Department of Cellular and Molecular Medicine School of Medicine University of California San Diego La Jolla 92093 CA United States Department of Surgery National Cheng Kung University Medical College and Hospital Taiwan Genomics Research Center Academia Sinica Taiwan The Ph.D. Program for Translational Medicine College of Medical Science and Technology Taipei Medical University and Academia Sinica Taipei 110 Taiwan Department of Neurobiology University of California San Diego La Jolla 92093 CA United States

Translational readthrough of UGA stop codons by selenocysteine-specific tRNA (tRNASec) enables the synthesis of selenoproteins. Seryl-tRNA synthetase (SerRS) charges tRNASec with serine, which is modified into selenocysteine and delivered to the ribosome by a designated elongation factor (eEFSec in eukaryotes). Here we found that components of the human selenocysteine incorporation machinery (SerRS, tRNASec, and eEFSec) also increased translational readthrough of non-selenocysteine genes, including VEGFA, to create C-terminally extended isoforms. SerRS recognizes target mRNAs through a stem-loop structure that resembles the variable loop of its cognate tRNAs. This function of SerRS depends on both its enzymatic activity and a vertebrate-specific domain. Through eCLIP-seq, we identified additional SerRS-interacting mRNAs as potential readthrough genes. Moreover, SerRS overexpression was sufficient to reverse premature termination caused by a pathogenic nonsense mutation. Our findings expand the repertoire of selenoprotein biosynthesis machinery and suggest an avenue for therapeutic targeting of nonsense mutations using endogenous factors. © 2023 The Author(s). Published by Oxford University Press on behalf of Nucleic Acids Research.

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Seasonal Influence on Pollution Index and Risk of Multiple Compositions of Microplastics in an Urban River

SSRN

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SSRN 2022年

作者： Huang, Chi-Wei Li, Yi-Lin Lin, Chitsan Bui, Xuan-Thanh Vo, Thi-dieu-Hien Ngo, Huu Hao Department of Marine Environmental Engineering National Kaohsiung University of Science and Technology Kaohsiung81157 Taiwan Ph.D. Program in Maritime Science and Technology College of Maritime National Kaohsiung University of Science and Technology Kaohsiung81157 Taiwan 268 Ly Thuong Kiet Street District 10 Ho Chi Minh City Viet Nam Linh Trung ward Ho Chi Minh City700000 Viet Nam Faculty of Environmental and Food Engineering Nguyen Tat Thanh University Ho Chi Minh City Viet Nam School of Civil and Environmental Engineering University of Technology Sydney SydneyNWS 2007 Australia

The emerging contaminant microplastics (MPs) are getting worldwide attention for their ubiquitous occurrence and potential risk in the environment. However, the seasonal influence on freshwater MP pollution remains poorly understood. To better understand and evaluate the riverine MPs in different seasons, this study conducted the risk assessment of MPs in an urban river, Houjin River, during the different seasons. The present study found that the MPs was more abundant in the dry season compared with wet seaon. Similarly, the mixture of different MPs polymers was more diverse in the dry season. The related pollution indexes such as the contamination factor (CF) and pollution load index (PLI) showed that the majority of the water samples in Houjin River was heavily polluted and higher in the dry season. The higher risk quotient (RQ) of MPs in the dry season was also observed. To sum up, the results of this study indicate the seasonal effects on the pollution and risk of multiple compositions of MPs in the urban river, suggesting higher impacts of riverine MPs pollution in the dry season, as well as the potential increase of MPs may lead to health risk in the future. © 2022, The Authors. All rights reserved.

关键词： Risk assessment

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Assessment of sources and health risks of heavy metals in metropolitan household dust among preschool children: The LEAPP-HIT study

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Journal of Environmental Management 2024年 352卷 120015页

作者： Kao, Chi-Sian Wang, Ying-Lin Jiang, Chuen-Bin Tai, Pei-Ju Chen, Yi-Hua Chao, Hsing-Jasmine Lo, Yu-Chun Hseu, Zeng-Yei Hsi, Hsing-Cheng Chien, Ling-Chu School of Public Health College of Public Health Taipei Medical University Taipei Taiwan Graduate Institute of Environmental Engineering National Taiwan University Taipei Taiwan Department of Pediatric Gastroenterology Hepatology and Nutrition MacKay Children's Hospital Taipei Taiwan Department of Medicine MacKay Medical College SanZhi District New Taipei City Taiwan Neuroscience Research Center Taipei Medical University Taipei Taiwan Ph.D. Program in Medical Neuroscience College of Medical Science and Technology Taipei Medical University Taipei Taiwan Department of Agricultural Chemistry National Taiwan University Taipei Taiwan Nutrition Research Center Taipei Medical University Hospital Taipei Taiwan

The most common construction material used in Taiwan is concrete, potentially contaminated by geologic heavy metals (HMs). Younger children spend much time indoors, increasing HM exposure risks from household dust owing to their behaviors. We evaluated arsenic (As), cadmium (Cd), and lead (Pb) concentrations in fingernails among 280 preschoolers between 2017 and 2023. We also analyzed HM concentrations, including As, Cd, Pb, chromium (Cr), nickel (Ni), copper (Cu), zinc (Zn), iron (Fe), and manganese (Mn), in 90 household dust and 50 road dust samples from a residential area where children lived between 2019 and 2021 to deepen the understanding of sources and health risks of exposure to HMs from household dust. The average As, Cd, and Pb concentrations in fingernails were 0.12 ± 0.06, 0.05 ± 0.05, and 0.95 ± 0.77 μg/g, respectively. Soil parent materials, indoor construction activities, vehicle emissions, and mixed indoor combustion were the pollution sources of HMs in household dust. Higher Cr and Pb levels in household dust may pose non-carcinogenic risks to preschoolers. Addressing indoor construction and soil parent materials sources is vital for children's health. The finding of the present survey can be used for indoor environmental management to reduce the risks of HM exposure and avoid potential adverse health effects for younger children. © 2024 Elsevier Ltd

关键词： Heavy metals

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