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检索条件"机构=Ph.D.Program in Biotechnology Research and Development"
41 条 记 录,以下是1-10 订阅
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7S,8R-dihydroxydeepoxysarcophytoxide: A natural dihydrofuranocembranoid from the octocoral Sarcophyton stellatum
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phytochemistry Letters 2024年 63卷 14-17页
作者: Sheu, Jyh-Horng Zheng, Li-Guo Chen, You-Ying Chien, Su-Ying Sung, Ping-Jyun Department of Marine Biotechnology and Resources National Sun Yat-sen University Chinese Medicine Research and Development Center China Medical University Hospital National Museum of Marine Biology and Aquarium Instrumentation Center National Taiwan University Graduate Institute of Natural Products Kaohsiung Medical University Ph.D. Program in Pharmaceutical Biotechnology Fu Jen Catholic University
Chemical screening of the octocoral Sarcophyton stellatum led to the isolation of a natural dihydrofuranocembranoid, 7S,8R-dihydroxydeepoxysarcophytoxide (1). Single-crystal X-ray diffraction analysis was conducted to... 详细信息
来源: 评论
Structure-guided identification and characterization of potent inhibitors targeting phoP and MtrA to combat mycobacteria
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Computational and Structural biotechnology Journal 2024年 23卷 1477-1488页
作者: Su, Han-Li Lai, Shu-Jung Tsai, Keng-Chang Fung, Kit-Man Lung, Tse-Lin Hsu, Hsing-Mien Wu, Yi-Chen Liu, Ching-Hui Lai, Hui-Xiang Lin, Jiun-Han Tseng, Tien-Sheng Department of Emergency Medicine Ditmanson Medical Foundation Chia-Yi Christian Hospital Chiayi City600 Taiwan Graduate Institute of Biomedical Sciences China Medical University Taichung Taiwan Research Center for Cancer Biology China Medical University Taichung Taiwan National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei Taiwan Ph.D. Program in Medical Biotechnology College of Medical Science and Technology Taipei Medical University Taipei Taiwan Academia Sinica Taipei11529 Taiwan Institute of Molecular Biology National Chung Hsing University Taichung Taiwan Department of Industrial Technology Ministry of Economic Affairs Taipei Taiwan Food Industry Research and Development Institute Hsinchu City Taiwan
Mycobacteria are causative agents of tuberculosis (TB), which is a global health concern. drug-resistant TB strains are rapidly emerging, thereby necessitating the urgent development of new drugs. Two-component signal... 详细信息
来源: 评论
Structure-Guided discovery of Pd-1/Pd-L1 Interaction Inhibitors: Peptide design, Screening, and Optimization via Computation-Aided phage display Engineering
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Journal of Chemical Information and Modeling 2024年 第5期64卷 1615-1627页
作者: Tseng, Tien-Sheng Lee, Chao-Chang Chen, Po-Juei Lin, Chiu-Yuen Chen, Wang-Chuan Lee, Yu-Ching Lin, Jiun-Han Chen, Kaun-Wen Tsai, Keng-Chang Institute of Molecular Biology National Chung Hsing University Taichung40202 Taiwan National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei11221 Taiwan The School of Chinese Medicine for Post Baccalaureate I-Shou University Kaohsiung824005 Taiwan Department of Chinese Medicine E-Da Hospital Kaohsiung824005 Taiwan TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei11031 Taiwan Ph.D. Program in Medical Biotechnology College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Department of Industrial Technology Ministry of Economic Affairs Taipei100210 Taiwan Food Industry Research and Development Institute Hsinchu30062 Taiwan Molecular Science and Digital Innovation Center Genetics Generation Advancement Corporation Taipei11949 Taiwan
Cancer immunotherapy harnesses the immune system to combat tumors and has emerged as a major cancer treatment modality. The Pd-1/Pd-L1 immune checkpoint modulates interactions between tumor cells and T cells and has b... 详细信息
来源: 评论
Sinulariaone A: a novel diterpenoid with a 13-membered carbocyclic skeleton from an octocoral Sinularia species
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RSC Advances 2023年 第15期13卷 10408-10413页
作者: Tseng, Hsuan-Jung Kuo, Liang-Mou Tsai, Yu-Chi Hu, Hao-Chun Chen, Po-Jen Chien, Su-Ying Sheu, Jyh-Horng Sung, Ping-Jyun Graduate Institute of Marine Biology National Dong Hwa University Pingtung944401 Taiwan National Museum of Marine Biology & Aquarium Pingtung944401 Taiwan Department of General Surgery Chang Gung Memorial Hospital at Chiayi Chiayi613016 Taiwan School of Chinese Medicine College of Chinese Medicine China Medical University Taichung404333 Taiwan Graduate Institute of Natural Products Kaohsiung Medical University Kaohsiung807378 Taiwan Clinical Immunology Laboratory Department of Medical Research E-Da Hospital I-Shou University Kaohsiung824005 Taiwan Instrumentation Center National Taiwan University Taipei106319 Taiwan Department of Marine Biotechnology and Resources National Sun Yat-sen University Kaohsiung804201 Taiwan Chinese Medicine Research and Development Center China Medical University Hospital Taichung404394 Taiwan Ph.D. Program in Pharmaceutical Biotechnology Fu Jen Catholic University New Taipei City242062 Taiwan
Chemical composition screening of an octocoral identified as Sinularia species led to the isolation of a novel diterpenoid, sinulariaone A (1), featuring a 13-membered carbocyclic skeleton. The structure of 1 was esta... 详细信息
来源: 评论
development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection
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Biomedicine and pharmacotherapy 2025年 183卷 117851-117851页
作者: Banerjee, Suddhasatwa Hsu, Ying-Ting Nguyen, duc-Hieu Yeh, Shiu-Hwa Liou, Ke-Chi Liu, Jr-Jiun Liou, Jing-Ping Chuang, Jian-Ying School of Pharmacy Taipei Medical University Taipei 11031 Taiwan Ph.D. Program in Medical Neuroscience Taipei Medical University and National Health Research Institutes Taipei 11031 Taiwan Institute of Biotechnology and Pharmaceutical Research National Health Research Institutes Miaoli County 35053 Taiwan TMU Research Center for Drug Discovery Taipei Medical University Taipei 11031 Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei 110 Taiwan International Master Program in Medical Neuroscience Taipei Medical University New Taipei City 23564 Taiwan TMU Research Center of Neuroscience Taipei Medical University Taipei 11031 Taiwan Department of Biomedical Science and Environmental Biology Kaohsiung Medical University Kaohsiung 80780 Taiwan
Traumatic brain injury (TBI) constitutes a significant burden on global healthcare systems, especially affecting younger populations, where it is a leading cause of disability and mortality. Current treatments for TBI... 详细信息
来源: 评论
Prediction tools for assessing functional impacts of gene mutations in Clear Cell Renal Cell Carcinoma: A comparative study
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Computers in Biology and Medicine 2025年 第Pt A期192卷 110187-110187页
作者: Yang, Cheng-Hong Lin, Guan-Cheng Wu, Chih-Hsien Chen, Jin-Bor Chuang, Li-Yeh Department of Information Management Tainan University of Technology Tainan Taiwan Department of Electronic Engineering National Kaohsiung University of Science and Technology Kaohsiung Taiwan Drug Development and Value Creation Research Center Kaohsiung Taiwan Ph. D. Program in Biomedical Engineering Kaohsiung Medical University Kaohsiung Taiwan Division of Nephrology Department of Internal Medicine Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Taiwan Department of Chemical Engineering & Institute of Biotechnology and Chemical Engineering I-Shou University Kaohsiung Taiwan Taiwan
Renal cell carcinoma (RCC) is a well-known malignancy characterized by specific gene mutations that elevate its occurrence. It can be categorized into clear cell RCC (ccRCC), papillary RCC, and chromophobe RCC, which ... 详细信息
来源: 评论
16-Hydroxybriaranes from the octocoral Briareum stechei
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phytochemistry Letters 2023年 第1期57卷 92-95页
作者: Liu, Chia-Jung Wang, Chien-Chiao Chang, Chun-Feng Zhang, Mingzi M. Tsou, Lun Kelvin Wen, Zhi-Hong Hwang, Tsong-Long Chen, You-Ying Sung, Ping-Jyun Department of Marine Biotechnology and Resources National Sun Yat-sen University Kaohsiung 804201 Taiwan National Museum of Marine Biology and Aquarium Pingtung 944401 Taiwan Graduate Institute of Natural Products College of Medicine Chang Gung University Taoyuan 333323 Taiwan Graduate Institute of Biomedical Sciences College of Medicine Chang Gung University Taoyuan 333323 Taiwan Division of Urology Department of Surgery Kaohsiung Armed Forces General Hospital Kaohsiung 802301 Taiwan Institute of Molecular and Genomic Medicine National Health Research Institutes Miaoli Zhunan 350401 Taiwan Institute of Biotechnology and Pharmaceutical Research National Health Research Institutes Miaoli Zhunan 350401 Taiwan Department of Anesthesiology Chang Gung Memorial Hospital Taoyuan 333008 Taiwan Research Center for Chinese Herbal Medicine Graduate Institute of Healthy Industry Technology College of Human Ecology Chang Gung University of Science and Technology Taoyuan 333324 Taiwan Department of Chemical Engineering Ming Chi University of Technology New Taipei 243303 Taiwan Chinese Medicine Research and Development Center China Medical University Hospital Taichung 404394 Taiwan Graduate Institute of Natural Products Kaohsiung Medical University Kaohsiung 807378 Taiwan Ph.D. Program in Pharmaceutical Biotechnology Fu Jen Catholic University New Taipei City 242062 Taiwan
Two new 16-hydroxybriaranes, 11-dehydroxybriavioid B (1) and 12-epi-briastecholide L (2), have been isolated from an algal-containing octocoral identified as Briareum stechei. The structures of metabolites 1 and 2 wer... 详细信息
来源: 评论
Reporting ethical approval in case reports and case series in 12 consecutive years: A systematic review
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Health Care Science 2024年 第5期3卷 298-311页
作者: Linh Tran Vuong Thanh Huan Luu Lam Thang Tai Adnan Safi Moustafa ElBadry Ahmed Mohamed Osman Algazar Sedighe Karimzadeh Nguyen Vinh Khang Nguyen Hai Nam Zaheer Ahmad Qureshi Nguyen Lam Vuong Le Huu Nhat Minh Nguyen Tien Huy University of Health Sciences Vietnam National University Ho Chi Minh CityHo Chi Minh CityVietnam Department of Sport Medicine Pham Ngoc Thach University of MedicineHo Chi Minh CityVietnam Department of Cardiology City Children HospitalHo Chi Minh CityVietnam Department of Medicine Lahore General HospitalLahorePakistan Faculty of Medicine Sohag UniversitySohagEgypt Neurology Department Alharam HospitalGizaEgypt Department of Pharmaceutical Sciences School of Pharmacy and Pharmaceutical SciencesUniversity of California IrvineIrvineCaliforniaUSA Department of Neurology University Medical CenterHo Chi Minh CityVietnam Department of Liver Tumor Cancer CenterCho Ray HospitalHo Chi Minh CityVietnam Liver Transplant Unit Cancer CenterCho Ray HospitalHo Chi Minh CityVietnam The Frank H.Netter M.D School of Medicine at Quinnipiac University BridgeportUSA Department of Medical Statistics and Informatics Faculty of Public HealthUniversity of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam International Ph.D.Program in Medicine College of MedicineTaipei Medical UniversityTaipeiTaiwanChina Global Clinical Scholars Research Training Program Harvard Medical SchoolBostonMassachusettsUSA Institute of Research and Development Duy Tan UniversityDa NangVietnam School of Medicine and Pharmacy Duy Tan UniversityDa NangVietnam School of Tropical Medicine and Global Health(TMGH) Nagasaki UniversityNagasakiJapan
Our study describes the reported rate of the Institutional Review Board(IRB)approval,declaration of Helsinki(doH),and informed consent in the case reports and case series and investigates factors associated with the e... 详细信息
来源: 评论
Polymethoxyflavone from Citrus depressa as an inhibitor against various variants of SARS-CoV-2 spike protein
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Journal of Ethnopharmacology 2024年 320卷 117412页
作者: Liu, Ta-Wei Hsu, Su-Jung Hsieh, Yves S.Y. Liu, Hui-Kang Lee, Ching-Kuo School of Pharmacy College of Pharmacy Taipei Medical University Taipei 11042 Taiwan Graduate Institute of Pharmacognosy College of Pharmacy Taipei Medical University Taipei 11042 Taiwan Division of Glycoscience Department of Chemistry School of Engineering Sciences in Chemistry Biotechnology and Health KTH Royal Institute of Technology AlbaNova University Centre Stockholm SE106 91 Sweden National Research Institute of Chinese Medicine (NRICM) Ministry of Health and Welfare Taipei City Taiwan Ph. D. Program in the Clinical Drug Development of Herbal Medicine Taipei Medical University Taipei Taiwan
Ethnopharmacological relevance: In traditional Taiwanese medicine, Citrus depressa Hayata serves as the raw material of Chen-Pi which has been widely used to treat respiratory ailments. Scientific investigations have ... 详细信息
来源: 评论
Biological Evaluation of Sulfonate and Sulfate Analogues of Lithocholic Acid: A Bioisosterism-Guided Approach Towards the discovery of Potential Sialyltransferase Inhibitors for Antimetastatic Study
SSRN
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SSRN 2023年
作者: Perez, Ser John Lynon P. Chen, Chia-Ling Chang, Tzu-Ting Li, Wen-Shan Institute of Chemistry Academia Sinica Taipei115 Taiwan Department of Applied Chemistry National Yang Ming Chiao Tung University Hsinchu300 Taiwan Sustainable Chemical Science and Technology Taiwan International Graduate Program Academia Sinica Taipei115 Taiwan Biomedical Translation Research Center Academia Sinica Taipei115 Taiwan Department of Medicinal and Applied Chemistry College of Life Science Kaohsiung Medical University Kaohsiung807 Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taiwan Doctoral Degree Program in Marine Biotechnology National Sun Yat-Sen University Kaohsiung804 Taiwan Department of Chemistry College of Science Tamkang University New Taipei City251 Taiwan
The naturally occurring bile acid lithocholic acid (LCA) has been a crucial core structure for many non-sugar-containing sialyltranferase (ST) inhibitors documented in literature. With the aim of elucidating the impac... 详细信息
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