咨询与建议

限定检索结果

文献类型

  • 9 篇 期刊文献

馆藏范围

  • 9 篇 电子文献
  • 0 种 纸本馆藏

日期分布

学科分类号

  • 6 篇 医学
    • 5 篇 临床医学
    • 2 篇 基础医学(可授医学...
    • 2 篇 药学(可授医学、理...
    • 1 篇 公共卫生与预防医...
  • 4 篇 理学
    • 4 篇 化学
    • 2 篇 生物学
    • 1 篇 物理学
  • 3 篇 工学
    • 2 篇 化学工程与技术
    • 2 篇 生物医学工程(可授...
    • 1 篇 仪器科学与技术
    • 1 篇 信息与通信工程
  • 1 篇 农学

主题

  • 1 篇 tumor angiogenes...
  • 1 篇 metastatic cance...
  • 1 篇 cancer
  • 1 篇 tumor immunity
  • 1 篇 gastrointestinal...
  • 1 篇 cancer stem cell...
  • 1 篇 stat3
  • 1 篇 cancer treatment
  • 1 篇 cxcr4
  • 1 篇 tumor metastasis
  • 1 篇 cell proliferati...
  • 1 篇 polymerization
  • 1 篇 death
  • 1 篇 quantities
  • 1 篇 chemotherapy
  • 1 篇 a_(2b)adenosine ...
  • 1 篇 metastasis
  • 1 篇 cd73/a_(2)adenos...
  • 1 篇 withaferin a

机构

  • 2 篇 school of pharma...
  • 2 篇 graduate institu...
  • 2 篇 the phd program ...
  • 2 篇 phd program for ...
  • 2 篇 division of card...
  • 1 篇 clinical drug de...
  • 1 篇 division of colo...
  • 1 篇 ph.d. program in...
  • 1 篇 school of post-b...
  • 1 篇 upmc hillman can...
  • 1 篇 national taiwan ...
  • 1 篇 department of su...
  • 1 篇 phd program in d...
  • 1 篇 taipei medical u...
  • 1 篇 school of pharma...
  • 1 篇 school of pharma...
  • 1 篇 division of pulm...
  • 1 篇 division of gene...
  • 1 篇 division of urol...
  • 1 篇 present address:...

作者

  • 2 篇 shuen-kuei liao
  • 2 篇 ansar muhamad
  • 2 篇 chen lung-ching
  • 2 篇 huang hsu-shan
  • 2 篇 sumitra maryam r...
  • 2 篇 lawal bashir
  • 1 篇 see-tong pang
  • 1 篇 lee hsueh-yun
  • 1 篇 prof. dr. maria ...
  • 1 篇 chiu li-pin
  • 1 篇 mokgautsi ntlotl...
  • 1 篇 shih-wei wang
  • 1 篇 dr. agostino cia...
  • 1 篇 yi-lin hwang
  • 1 篇 lin l.c.
  • 1 篇 shih-chieh hsiun...
  • 1 篇 prof. dr. giusep...
  • 1 篇 wang shih-wei
  • 1 篇 wang hong-jaan
  • 1 篇 wu c.h.

语言

  • 8 篇 英文
  • 1 篇 其他
检索条件"机构=PhD Program in Drug Discovery and Development"
9 条 记 录,以下是1-10 订阅
Structure-based design, synthesis and biological evaluation of N-substituted 6H-thiochromeno[2,3–c]quinolin-12(12H)-one as potential breast cancer drugs
收藏 引用
Arabian Journal of Chemistry 2024年 第1期17卷
作者: Sumitra, Maryam Rachmawati Chen, Lung-Ching Tsai, Wei-Chen Ansar, Muhamad Lawal, Bashir Mokgautsi, Ntlotlang Guh, Jih-Hwa Wu, Alexander T.H Huang, Hsu-Shan PhD Program for Cancer Molecular Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Graduate Institute of Cancer Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Division of Cardiology Department of Internal Medicine Shin Kong Wu Ho-Su Memorial Hospital Taipei11101 Taiwan School of Medicine Fu Jen Catholic University New Taipei24205 Taiwan School of Pharmacy National Defense Medical Center Taipei11490 Taiwan Clinical Drug Development of Herbal Medicine Taipei Medical University Taipei11031 Taiwan The PhD Program of Translational Medicine College of Science and Technology Taipei Medical University Taipei11031 Taiwan Clinical Research Center Taipei Medical University Hospital Taipei Medical University Taipei11031 Taiwan Graduate Institute of Medical Sciences National Defense Medical Center Taipei11490 Taiwan School of Pharmacy National Taiwan University No. 33 Linsen S. Rd. Zhongzheng Dist. Taipei10025 Taiwan Biotechnology Research and Development College of Pharmacy Taipei Medical University Taipei11031 Taiwan
Tetraheterocyclic compounds, derived from natural sources and contemporary pharmaceuticals, have shown promise as multitarget therapeutic agents. However, their mechanisms of action remain partially understood. In thi... 详细信息
来源: 评论
Computer-aided drug discovery of a dual-target inhibitor for ovarian cancer: therapeutic intervention targeting CDK1/TTK signaling pathway and structural insights in the NCI-60
收藏 引用
Computers in Biology and Medicine 2025年 193卷 110445页
作者: Tang, Sung-Ling Sumitra, Maryam Rachmawati Kuo, Yu-Cheng Hsu, Han-Lin Ansar, Muhamad Huang, Sheng-Liang Lee, Shih-Yu Wang, Hong-Jaan Lawal, Bashir Wu, Alexander T.H. Chen, Lung-Ching Huang, Hsu-Shan School of Pharmacy National Defense Medical Center Taipei11490 Taiwan PhD Program for Cancer Molecular Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Graduate Institute of Cancer Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Department of Pharmacology School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan School of Post-Baccalaureate Chinese Medicine College of Chinese Medicine China Medical University Taichung40604 Taiwan Graduate Institute of Clinical Medicine Taipei Medical University Taipei11031 Taiwan Division of Pulmonary Medicine Department of Internal Medicine Wanfang Hospital Taipei Medical University Taipei11031 Taiwan Ph.D. Program in the Clinical Drug Development of Herbal Medicine Taipei Medical University Taipei110301 Taiwan Graduate Institute of Aerospace and Undersea Medicine National Defense Medical Center Taipei11490 Taiwan UPMC Hillman Cancer Center University of Pittsburgh PittsburghPA United States Ph.D. Program of Translational Medicine College of Science and Technology Taipei Medical University Taipei11031 Taiwan Division of Cardiology Department of Internal Medicine Shin Kong Wu Ho-Su Memorial Hospital Taipei11101 Taiwan Ph.D. Program in Biotechnology Research and Development College of Pharmacy Taipei Medical University Taipei11031 Taiwan
Ovarian cancer remains the third most prevalent and deadliest gynecologic malignancy worldwide, with most patients eventually developing resistance to platinum-based chemotherapy. This highlights a critical unmet need... 详细信息
来源: 评论
CuI-mediated synthesis of 1-aryl-5,6,7-trimethoxybenzimidazoles as potent antitubulin agents
收藏 引用
RSC Advances 2023年 第19期13卷 13169-13176页
作者: Peng, Cong-Min Wang, Shih-Wei Hwang, Yi-Lin Sun, Wen-Chun Chiu, Li-Pin Liu, Yi-Ting Lai, Yu-Wei Lee, Hsueh-Yun School of Pharmacy College of Pharmacy Taipei Medical University Taipei Taiwan Institute of Biomedical Sciences MacKay Medical College New Taipei City Taiwan Department of Medicine MacKay Medical College New Taipei City Taiwan School of Pharmacy College of Pharmacy Kaohsiung Medical University Kaohsiung Taiwan Division of Colon and Rectal Surgery Department of Surgery MacKay Memorial Hospital Taipei Taiwan Division of General Surgery Taipei City Hospital Chushing Branch Taipei Taiwan General Education Center University of Taipei Taipei Taiwan Division of Urology Taipei City Hospital Renai Branch Taipei Taiwan Department of Urology School of Medicine and Shu-Tien Urological Science Research Center National Yang Ming Chiao Tung University Taipei Taiwan PhD Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei Taiwan TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei Taiwan
In situ CuI-mediated cyclization methodology helped yield benzimidazoles with different substitution manner, such as 1,2-diarylbenzimidazoles (4 and 5) and 1-arylbenzimidazoles (6-15). The result of structure-activity... 详细信息
来源: 评论
Front Cover: Prodrug Approach to Exploit (S)-Alanine Amide as Arginine Mimic Moiety in the development of Protein Arginine Methyltransferase 4 Inhibitors (ChemMedChem 17/2024)
收藏 引用
ChemMedChem 2024年 第17期19卷
作者: Prof. Dr. Ciro Milite Giuliana Sarno Ida Pacilio Dr. Agostino Cianciulli Dr. Monica Viviano Dr. Giulia Iannelli Erica Gazzillo Dr. Alessandra Feoli Dr. Alessandra Cipriano Prof. Dr. Maria Giovanna Chini Prof. Dr. Sabrina Castellano Prof. Dr. Giuseppe Bifulco Prof. Dr. Gianluca Sbardella Department of Pharmacy University of Salerno via Giovanni Paolo II 132 84084 Fisciano SA Italy PhD Program in Drug Discovery and Development University of Salerno via Giovanni Paolo II 132 84084 Fisciano SA Italy Present Address: Center for Drug Discovery and Development-DMPK Aptuit an Evotec Company Via A. Fleming4 37135 Verona Italy Present Address: Institute of Organic Chemistry University of Vienna WähringerStraße38 1090 Wien Austria Dipartimento di Bioscienze e Territorio University of Molise Contrada Fonte Lappone 86090 Isernia Italy
来源: 评论
Correction: CuI-mediated synthesis of 1-aryl-5,6,7-trimethoxybenzimidazoles as potent antitubulin agents
收藏 引用
RSC advances 2023年 第22期13卷 14878页
作者: Cong-Min Peng Shih-Wei Wang Yi-Lin Hwang Wen-Chun Sun Li-Pin Chiu Yi-Ting Liu Yu-Wei Lai Hsueh-Yun Lee School of Pharmacy College of Pharmacy Taipei Medical University Taipei Taiwan hyl@tmu.edu.tw. Institute of Biomedical Sciences MacKay Medical College New Taipei City Taiwan. Department of Medicine MacKay Medical College New Taipei City Taiwan. School of Pharmacy College of Pharmacy Kaohsiung Medical University Kaohsiung Taiwan. Division of Colon and Rectal Surgery Department of Surgery MacKay Memorial Hospital Taipei Taiwan. Division of General Surgery Taipei City Hospital Chushing Branch Taipei Taiwan. General Education Center University of Taipei Taipei Taiwan. Division of Urology Taipei City Hospital Renai Branch Taipei Taiwan dai77@tpech.gov.tw. Department of Urology School of Medicine and Shu-Tien Urological Science Research Center National Yang Ming Chiao Tung University Taipei Taiwan. PhD Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei Taiwan. TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei Taiwan.
[This corrects the article DOI: 10.1039/D3RA01927F.].
来源: 评论
Role of adenosine in tumor progression: focus on A_(2B) receptor as potential therapeutic target
收藏 引用
Journal of Cancer Metastasis and Treatment 2017年 第1期3卷 127-138页
作者: Claudia Sorrentino Silvana Morello Department of Pharmacy University of Salerno84084 Fisciano(SA)Italy PhD Program in Drug Discovery and Development Department of PharmacyUniversity of Salerno84084 Fisciano(SA)Italy.
Adenosine receptors are a family of G-coupled receptors which mediate the anti-inflammatory and immune-suppressive effects of adenosine in a damaged tissue.A large number of evidence indicate that the accumulation of ... 详细信息
来源: 评论
PO-244 Inhibitory effects of isoliquiritigenin on TGF-β-induced epithelial-to-mesenchymal transition of human endometrial cancer cells
收藏 引用
ESMO Open 2018年 3卷 A322-A322页
作者: Hsia, S.M. Huang, J.S. Chen, H.Y. Huang, T.C. Lin, L.C. Wu, C.H. Shieh, T.M. Taipei Medical University School of Nutrition and Helath Sciences Taipei Taiwan Taipei Medical University School of Nutrition and Health Sciences Taipei Taiwan Taipei Medical University and Academia Sinica PhD Program for Cancer Biology and Drug Discovery Taipei Taiwan National Taiwan Normal University Department of Human Development and Family Studies Taipei Taiwan China Medical University Department of Dental Hygiene Taichung Taiwan
ABSTRACTIntroductionEndometrial cancer is a common gynaecological cancer in western countries. Death and prognosis of most patients with cancer are related to tumour metastasis and invasion. In cancer metastasis, epit...
来源: 评论
Introduction to the Special Issue on Cancer Immunotherapy
收藏 引用
Journal of Cancer Metastasis and Treatment 2017年 第1期3卷 217-217页
作者: Shuen-Kuei Liao The PhD Program of Cancer Biology and Drug Discovery Taipei Medical UniversityTaipei 110TaiwanChina Department of Research and Development Vectorite Biomedica Inc.New Taipei City 221TaiwanChina.
The biotechnology revolution started in early 1970s following advances in molecular biology,specifically:(1)sophisticated methodologies for manipulating DNA in mammalian cells;(2)hybridoma technology for the generatio... 详细信息
来源: 评论
Withaferin A targeting both cancer stem cells and metastatic cancer stem cells in the UP-LN1 carcinoma cell model
收藏 引用
Journal of Cancer Metastasis and Treatment 2016年 第1期2卷 29-40页
作者: Lai-Lei Ting Andy Shau-Bin Chou Chin-Hsuan Hsieh Shih-Chieh Hsiung See-Tong Pang Shuen-Kuei Liao Department of Radiation Oncology Cancer CenterTaipei Medical University HospitalTaipei 110TaiwanChina Department of Radiology Tzu-Chi General HospitalHualien 970TaiwanChina Department of Surgery Division of Uro-OncologyChang Gung Memorial HospitalCollege of MedicineChang Gung UniversityTaoyuan 333TaiwanChina The PhD Program of Cancer Biology and Drug Discovery Taipei Medical UniversityTaipei 110TaiwanChina Department of Research and Development Vectorite Biomedica Inc.New Taipei City 221TaiwanChina
Aim:As our understanding of cancer stem cell(CSC)biology improves,search for inhibitory agents of CSCs and metastatic CSCs(mCSCs)positive for CXCR4 is *** A(WA),a withanolide extracted from the medicinal plant Withani... 详细信息
来源: 评论