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Probabilistic genotype-phenotype maps reveal mutational robustness of RNA folding, spin glasses, and quantum circuits

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Physical Review Research 2025年第1期7卷 013118-013118页

作者： Anna Sappington Vaibhav Mohanty Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Harvard-MIT Program in Health Sciences and Technology Harvard Medical School Boston Massachusetts 02115 USA and Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Harvard/MIT MD-PhD Program Harvard Medical School Boston Massachusetts 02115 USA and Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Department of Chemistry and Chemical Biology Harvard University Cambridge Massachusetts 02138 USA

Recent studies of genotype-phenotype maps have reported universally enhanced phenotypic robustness to genotype mutations, a feature essential to evolution. Virtually all of these studies make a simplifying assumption that each genotype—represented as a sequence—maps deterministically to a single phenotype, such as a discrete structure. Here we introduce probabilistic genotype-phenotype (PrGP) maps, where each genotype maps to a vector of phenotype probabilities, as a more realistic and universal language for investigating robustness in a variety of physical, biological, and computational systems. We study three model systems to show that PrGP maps offer a generalized framework which can handle uncertainty emerging from various physical sources: (1) thermal fluctuation in RNA folding, (2) external field disorder in the spin-glass ground state search problem, and (3) superposition and entanglement in quantum circuits, which are realized experimentally on IBM quantum computers. In all three cases, we observe a biphasic robustness scaling which is enhanced relative to random expectation for more frequent phenotypes and approaches random expectation for less frequent phenotypes. We derive an analytical theory for the behavior of PrGP robustness, and we demonstrate that the theory is highly predictive of empirical robustness.

关键词： Quantum computers

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Instantaneous dynamic phasor estimates with Kalman filter

Instantaneous dynamic phasor estimates with Kalman filter

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IEEE PES General Meeting, PES 2010

作者： De La O Serna, José Antonio Rodríguez, Johnny PhD Electrical Engineering Program UANL Monterrey Mexico

ISBN: (纸本)9781424483570

The state-transition matrix of the κ-th order Taylor approximation to the dynamic phasor and its first derivatives leads to a plurality of state-space representations to approach the bandpass signal model of a power oscillation. With these truncated signal models, the Kalman filter algorithm can be applied to their state vectors in order to find observers able to estimate the dynamic phasor and its first derivatives. The estimates obtained through this technique are not only instantaneous (no delay) but also synchronous, an important attribute for control applications. Even if the results are in their preliminary stage, they are promising and open the way to a new family of phasor estimators. ©2010 IEEE.

关键词： Kalman filters

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ARCH: Automatic Roaming-contract Handler for Seamless 6G System to Provide Trusted and Highly Available Network Access 23

ARCH: Automatic Roaming-contract Handler for Seamless 6G Sys...

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29th Annual International Conference on Mobile Computing and Networking, MobiCom 2023

作者： Tenn, Kíng-Pîng Ho, Po-Han Chen, Hong-Yen Lin, Tsung-Nan Department of Electrical Engineering PhD Program in Cybersecurity National Taiwan University Taipei60005429 Taiwan

ISBN: (纸本)9781450399906

It is expected to be pervasive sensors to integrate physical and digital world. Low-latency and wide-covering networks are hence urged, which lead to costly infrastructure. We are proposing ARCH based on smart contract and Self-sovereign Identity (SSI), to provide telecoms a trusted and transparent multilateral platform sharing their infrastructure to decrease the deployment and agency cost, and carbon emission. © 2023 Owner/Author(s).

关键词： Smart contract

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Probabilistic Power Flow Analysis Based on Low Rank Approximation and Principle Component Analysis

Probabilistic Power Flow Analysis Based on Low Rank Approxim...

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2020 International Conference on Power, Energy and Innovations, ICPEI 2020

作者： Laowanitwattana, Jirasak Uatrongjit, Sermsak Chiang Mai University PhD's Degree Program in Electrical Engineering Faculty of Engineering Chiang Mai Thailand Chiang Mai University Faculty of Engineering Department of Electrical Engineering Chiang Mai Thailand

ISBN: (纸本)9781728172408

Probabilistic power flow (PPF) analysis is usually applied for evaluating the effects of uncertain parameters on power system performances. This paper presents a technique to enhance the arbitrary polynomial chaos expansion (aPCE) based PPF analysis technique when applying to system with many uncertain parameters. The proposed method represents a power system response as low rank approximation (LRA). In addition, the principle component analysis (PCA) is applied to reduce the number of uncertain parameters and also de-correlate them. This combination enables the proposed method to perform PPF of the power system having large number of uncertain parameters. Based on preliminary numerical results on the modified IEEE 57-bus system, it can be noticed that the proposed modified method is able to find accurate statistical characteristics of the responses but uses less computation time compared to the MCS based PPF analysis. © 2020 IEEE.

关键词： Uncertainty analysis

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Reducing the delay of phasor estimates under power system oscillations

Reducing the delay of phasor estimates under power system os...

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2005 IEEE Power engineering Society General Meeting

作者： De La O Serna, José A. PhD. Program on Electrical Engineering State University of Nuevo León Monterrey Nuevo León 66450 Mexico

ISBN: (纸本)078039156X

Delay and computational complexity reduction on the phasor estimates calculated under power system oscillations is the main objective of this paper. Different approximations to the Raised Cosine (RC) filter lead to a reduction in delay and computational complexity of the phasor estimates. As for finite impulse response (FIR) filters, the minimum-phase implementation of the RC linear-phase FIR filter reduces by a half the delay of the phasor estimates, without introducing significant phase distortion and with shorter transients. This improvement in speed provides faster estimates for real-time monitoring and control applications. On the other hand, infinite impulse response (IIR) filters reduce the computational complexity of the estimates by a factor of ten, but without significant delay reduction, introducing a higher distortion, and with longer transient behavior. This solution could be useful for implementations in which computational complexity is a matter of serious concern. In this way, the paper provides a wide range of solutions for those who need more accurate, faster or simpler estimates. © 2005 IEEE.

关键词： Electric power systems

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Arcing faults patterns for based ANN relays for transmission lines

Arcing faults patterns for based ANN relays for transmission...

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2003 IEEE Bologna PowerTech Conference

作者： Ortiz, V.H. Uribe, F.A. Gutierrez, J.A. Altuve, H.J. PhD Program Nuevo Leon University Mexico Department of Electrical Engineering Guadalajara University Mexico Department of Mathematics University of Guadalajara Mexico Schweitzer Engineering Laboratories Inc Mexico

ISBN: (纸本)0780379675

A frequency domain technique for calculating arcing faults in transmission lines is applied to obtain relaying signals. There are analyzed the transient signals in order to discover distinctive features. The paper later center the attention on feature extractors to improve digital relays speed and pattern recognition with ANN. Non-conventional signal processing are explained for a based artificial neural network (ANN) relay for transmission line protection. © 2003 IEEE.

关键词： Electric lines

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Economic comparison of deloaded-wind and wind-battery systems

Economic comparison of deloaded-wind and wind-battery system...

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2014 6th Annual IEEE Green Technologies Conference, GREENTECH 2014

作者： Singarao, Venkatesh Yadav Nimmagadda, Sandeep Rao, Vittal Multi-Disciplinary Wind Science and Engineering PhD Program Texas Tech University Lubbock United States Electrical and Computer Engineering Texas Tech University Lubbock United States Department of Electrical and Computer Engineering Texas Tech University Lubbock United States

ISBN: (纸本)9781479939336

With the increasing grid penetration levels of wind power, there is a large need for the energy reserves for grid support during under-frequency conditions. Such energy reserves are created by operating the wind farm at non-optimum/deloaded operating points, as well as through storage of excess energy in Batteries. This paper provides technical and economic analysis of the above strategies and thus provides a case comparison of deloaded wind farm to that of wind-Battery system. A simplified Excel-based Proforma financial model has been developed to perform sensitivity analysis, as well as to obtain the impact of these strategies on the cost of energy. © 2014 IEEE.

关键词： Electric batteries

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A Storage and Transmission Joint Planning Method for Centralized Wind Power Transmission

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Computers, Materials & Continua 2021年第7期68卷 1081-1097页

作者： Xiuyu Yang Qi Guo Jianzhong Gui Renyong Chai Xueyuan Liu Key Laboratory of Modern Power System Simulation and Control&Renewable Energy Technology(Northeast Electric Power University) Jilin132012China Electrical Engineering-PHD program at the University of Idaho Idaho83843America State Grid Jiangxi Power Supply Company Xinyu338025China

Centralized delivery has become the main operation mode under the scaled development of wind *** channels are usually the guarantee of out-delivered wind power for large-scale wind *** configuration of transmission capacity,which has the features of low utilization and poor economy,is hardly matching correctly due to the volatility and low energy density of *** usage of energy storage can mitigate wind power fluctuations and reduce the requirement of out-delivery transmission capacity,but facing the issue of energy storage cost ***,it is necessary to optimize the allocation of energy storage while considering the problem of wind power *** paper studies the joint optimization of large-scale wind power transmission capacity and energy storage,reveals the mechanism of energy storage in order to reduce the power fluctuation of wind power base and slow down the demand of ***,analyze the multi-functional cost-sharing mode of energy storage,improve the efficiency of energy storage cost *** the coordination optimization configuration model to deal with the problem of large-scale wind power transmission capacity and energy storage,and realizes the transmission capacity optimization coordination and optimization with energy *** proposed method is verified by a wind base located in Northeast China.

关键词： Wind farm group energy storage configuration transmission capacity coordination and optimization

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Optimized photonic integrated circuit components for optical coherence tomography at 1060 nm

Optimized photonic integrated circuit components for optical...

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2024 Conference on Lasers and Electro-Optics, CLEO 2024

作者： Hao, Senyue Adkins, Aaron J. Zhang, Yitian Zhou, Chao Department of Electrical & Systems Engineering Washington University Saint Louis United States Imaging Science PhD Program Washington University Saint Louis United States Department of Biomedical Engineering Washington University Saint Louis United States

To implement optical coherence tomography on photonic chips, we developed optimized and experimentally validated silicon nitride-based components for photonic integrated circuits in order to achieve high sensitivity a... 详细信息

ISBN: (纸本)9781957171395

关键词： Photonic integrated circuits

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Optimized photonic integrated circuit components for optical coherence tomography at 1060 nm

Optimized photonic integrated circuit components for optical...

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CLEO: Applications and Technology in CLEO 2024, CLEO: A and T 2024 - Part of Conference on Lasers and Electro-Optics

关键词： Photonic integrated circuits

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