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Investigating the neural correlates of treatment-resistance depression: a white matter integrity study

neuroscience Applied 2024年 3卷

作者： C. Milano B. Bravi M. Paolini M. Maccario C. Colombo R. Zanardi F. Benedetti IRCCS San Raffaele Scientific Institute Division of Neuroscience- Psychiatry and Clinical Psychobiology Unit Milan Italy Vita-Salute San Raffaele University PhD program in Cognitive Neurosciences Milan Italy Vita-Salute San Raffaele University Mood Disorders Unit Milan Italy IRCCS Scientific Institute San Raffaele Hospital Mood Disorders Unit Milan Italy Vita-Salute San Raffaele University Medicine and Surgery Faculty Milan Italy Vita-Salute San Raffaele University Psychology Faculty Milan Italy

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Associations between gut microbial families and brain myelin in a human cohort

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Alzheimer's & Dementia 2022年第S6期18卷

作者： Kao Lee Yang Margo B. Heston Akshay Kohli Steven R Kecskemeti Antonio González Rob Knight Rima Kaddurah-Daouk Federico E. Rey Barbara B. Bendlin Neuroscience Training Program University of Wisconsin School of Medicine and Public Health Madison WI USA Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health Madison WI USA Cellular and Molecular Pathology PhD Program University of Wisconsin School of Medicine and Public Health Madison WI USA Waisman Center University of Wisconsin-Madison Madison WI USA Center for Microbiome Innovation University of California San Diego CA USA Department of Medicine Duke University Durham NC USA Department of Bacteriology University of Wisconsin Madison WI USA Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI USA

Background We previously reported brain myelin (Dean et al, 2017) and gut microbial composition alterations (Vogt et al, 2017) in Alzheimer’s disease (AD). Prior animal studies suggest that myelin is impacted by experimentally altered gut microbiota (Keogh et al, 2021), suggesting that gut microbiota may be linked to brain myelination. However, little is yet known about the human gut microbiome and myelin alterations in the context of AD. Here, we examined the gut-brain association in humans using biomarker and neuroimaging data. Method Amyloid positive (n=27) and negative (n=91) participants from the Wisconsin Alzheimer’s Disease Research Center and the Wisconsin Registry for Alzheimer’s Prevention were included based on completion of one MPnRAGE (Kecskemeti et al., 2018) scan and donation of one stool sample. Myelin was assessed using MPnRAGE-derived quantitative R1 and myelin content in 9 white matter tracts were examined as primary outcomes (Table). Intestinal microbiota composition was characterized using 16S rRNA sequencing of fecal samples. QIIME2 was used to denoise and classify features. Phyloseq was used to filter rare taxa, compute relative abundances, and agglomerate at the family taxonomic rank, resulting in 35 microbial families used as primary predictors. Multiple regression was used to test associations between each microbial family and regional myelin content. Benjamini-Hochberg false discovery rate (FDR) adjustment was applied post-regression; results were considered significant at q <.05. Result Microbial family Turicibacteraceae was positively associated with myelin indexed by R1 (Figure) in the forceps minor (b=.014, q =.037) and uncinate fasciculus (b=.011, q =.028). Across all white matter tracts, higher age was associated with lower R1. Interestingly, there was a significant Paraprevotellaceae -by-amyloid effect in the superior longitudinal fasciculus (b= -.017, p =.031) and Clostridiaceae -by-amyloid effect in the forceps major (b=.002, p =.

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26th Annual Computational neuroscience Meeting (CNS*2017) of the Organization for Computational neuroscience Antwerp, Belgium, July 15-20, 2017

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BMC neuroscience 2017年第SUPPL 1期18卷 59-59页

作者： [Anonymous] Indiana University Purdue University Indianapolis Indianapolis IN 46032 USA Stark Neurosciences Research Institute Indiana University School of Medicine Indianapolis IN 46032 USA Department of Mathematics East Carolina University Greenville NC 27858 USA Jülich Supercomputing Centre Forschungszentrum Jülich 52425 Jülich Germany Future Systems Swiss National Supercomputing Centre 8092 Zurich Switzerland User Engagement and Support Swiss National Supercomputing Centre 6900 Lugano Switzerland Institut de Neurosciences des Systèmes Aix Marseille Univ 13005 Marseille France Simulation Lab Neuroscience Forschungszentrum Jülich Jülich Germany Department of Experimental Psychology Ghent University 9000 Ghent Belgium Donders Center for Cognitive Neuroimaging Radboud University 6525HR Nijmegen The Netherlands Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO 80309 USA Department of Neurosurgery Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Neurology Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Otolaryngology Johns Hopkins School of Medicine Baltimore MD 21287 USA INSERM U968 Paris France Sorbonne Universités UPMC University Paris 06 UMR_S 968 Institut de la Vision Paris France CNRS UMR_7210 Paris France Department of Computer Architecture and Technology University of Granada (CITIC) Granada Spain Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Institut de la Vision Paris France Department of Adaptive Machine Systems Osaka University Osaka Japan Department of Computer Science University of Cergy-Pontoise Cergy-Pontoise France Department of Physics and Astronomy College of Charleston Charleston SC 29424 USA School of Physics Faculty of Science University of Sydney Sydney NSW 2006 Australia Center of Excellence for Integrative Brain Function Australian Research Council Sydney Australia Max Planck Institute for Human Cognitive and Brain Sciences Saxony Lei

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Correction to: Demographic and clinical determinants of neck pain in idiopathic cervical dystonia

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Journal of neural transmission (Vienna, Austria : 1996) 2021年第6期128卷 869-870页

作者： Michele Tinazzi Roberto Erro Marcello Mario Mascia Marcello Esposito Tommaso Ercoli Gina Ferrazzano Francesca Di Biasio Roberta Pellicciari Roberto Eleopra Francesco Bono Laura Bertolasi Paolo Barone Cesa Lorella Maria Scaglione Antonio Pisani Maria Concetta Altavista Maria Sofia Cotelli Roberto Ceravolo Giovanni Cossu Maurizio Zibetti Mario Coletti Moja Paolo Girlanda Luca Maderna Alberto Albanese Martina Petracca Luca Magistrelli Salvatore Misceo Brigida Minafra Marcello Romano Giovanna Maddalena Squintani Nicola Modugno Marco Aguggia Daniela Cassano Anna Castagna Francesca Morgante Alfredo Berardelli Giovanni Defazio Neurology Unit Department of Neuroscience Biomedicine and Movement University of Verona Verona Italy. Department of Medicine Surgery and Dentistry "Scuola Medica Salernitana" University of Salerno Baronissi SA Italy. Neurology Unit Department of Medical Science and Public Health Institute of Neurology University of Cagliari Cagliari Italy. Clinical Neurophysiology Unit Cardarelli Hospital Naples Italy. Neurology Unit Department of Medical Science and Public Health Institute of Neurology University of Cagliari Cagliari Italy. ercolitommaso@***. Department of Human Neurosciences Sapienza University of Rome Rome Italy. Ospedale Policlinico San Martino IRCCS Genoa Italy. Department of Basic Science Neuroscience and Sense Organs Aldo Moro University of Bari 70124 Bari Italy. Neurology Unit 1 Fondazione IRCSS Istituto Neurologico "Carlo Besta" Milan Italy. Center for Botulinum Toxin Therapy Neurology Unit A.O.U. Mater Domini Catanzaro Italy. Neurology Unit University Hospital Verona Italy. IRCCS Institute of Neurological Sciences Bologna Italy. Neurology Department of Systems Medicine University of Rome Tor Vergata Rome Italy. Neurology Unit San Filippo Neri Hospital ASL Roma 1 Rome Italy. Neurology Unit ASST Valcamonica Esine Italy. Neurology Unit Department of Clinical and Experimental Medicine University of Pisa Pisa Italy. Neurology Service and Stroke Unit Department of Neuroscience AO Brotzu Cagliari Italy. Department of Neuroscience 'Rita Levi Montalcini' University of Turin Turin Italy. Neurology Unit Umberto I Hospital Turin Italy. Department of Experimental and Clinical Medicine University of Messina Messina Italy. Department of Neurology and Laboratory of Neuroscience IRCCS Istituto Auxologico Italiano Milan Italy. Department of Neurology IRCCS Humanitas Research Hospital Rozzano Milan Italy. Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy. Institute of Neurology Università Cattolica del Sacro Cuore Rome I

The original version of this article unfortunately contained a mistake.

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CORTICAL DISINHIBITION AS A DOPAMINE-INDEPENDENT FEATURE IN MANIFESTED PARKINSON'S DISEASE

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IBRO neuroscience Reports 2023年 15卷 S357-S358页

作者： Claudia Ammann Michele Dileone Cristina Pagge David Mata-Marín Michele Matarrazzo Mariana H.G. Monje Álvaro Sánchez-Ferro Beatriz Fernández-Rodríguez Carmen Gasca-Salas Jorge Máñez-Miró Raúl Martínez-Fernández Lydia Vela-Desojo Fernando Alonso-Frech Antonio Oliviero Jose Ángel Obeso Guglielmo Foffani Hospital Universitario HM Puerta del Sur Hm Cinac (centro Integral De Neurociencias Abarca Campal) Móstoles Spain Camilo José Cela University of Madrid Faculty Of Health Madrid Spain Autonoma de Madrid University-Cajal Institute Phd Program In Neuroscience Madrid Spain Hospital Nacional de Parapléjicos Fennsi Group TOLEDO Spain Hospital Nacional de Parapléjicos Sescam Toledo Spain Instituto de Salud Carlos III Ciberned Madrid Spain SESCAM Hospital Nacional De Parapléjicos Toledo Spain

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Telomere length in the superager sample of the Vallecas Project cohort

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Alzheimer's & Dementia 2023年第S14期19卷

作者： Marta Garo Pascual Linda Zhang Miguel Calero Miguel Medina Javier Defelipe Bryan A Strange Centre for Biomedical Technology Universidad Politecnica de Madrid Madrid Spain PhD Program in Neuroscience Autonoma de Madrid University Madrid Spain CIEN Foundation Queen Sofia Foundation Alzheimer Centre Madrid Spain Correspondece CIBERNED Network Center for Biomedical Research in Neurodegenerative Diseases National Institute of Health Carlos III Madrid Spain Laboratorio Cajal de Circuitos Corticales Centro de Tecnología Biomédica (CTB) Universidad Politécnica de Madrid (UPM) Pozuelo de Alarcón Spain Instituto Cajal Centro Superior de Investigaciones Científicas (CSIC) Madrid Spain

Background Superagers are individuals aged 80 and over with youthful episodic memory that can provide insights into protective mechanisms against age-related memory loss and dementia. We aim to study telomere length in human superagers since telomere attrition is considered a hallmark of ageing and can explain some structural and functional changes occurring in an ageing organism. We therefore tested whether telomere length is associated with successful episodic memory of superagers. Method Telomere length was measured in peripheral blood cells from 57 superagers (mean age 81.9 years ± 2.0 std, 61.4% women) and 48 age-matched typical older adults with normal memory for age (mean age 82.4 years ± 1.9 std, 64.6% women) selected from the Vallecas Project cohort. A high-throughput quantitative fluorescence in situ hybridization technique (HT Q-FISH) (Life length, Spain) was used. This technology has a low detection limit of < 100 bp, enabling the quantification of short telomeres that can be more informative of telomere dysfunction than centrality measures. Result Superagers have significantly shorter median telomere lengths than typical older adults ( p = 0.0009, t = -3.4) and show a higher proportion of short telomeres (<6 Kbp) ( p = 0.0005, t = 3.6) and extremely short telomeres (<3 Kbp) ( p = 9. 4×10 −5 ; t = 4.1) than typical older adults. Thus, superagers have shorter average telomere lengths and a higher proportion of short telomeres, which are most associated with genome instability. Conclusion The successful episodic memory of our superager population is not associated with long telomere length or the presence of fewer short telomeres measured in a cross-sectional setting. Further analysis exploring telomere attrition rate of these two groups over time may help to interpret the current findings.

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Correction to: A kinematically complex multi‑articular motor skill for investigating implicit motor learning

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Psychological research 2024年第7期88卷 2020页

作者： Jack P Solomon Austin J Hurst Sarah N Kraeutner Tony G J Ingram Shaun G Boe Laboratory for Brain Recovery and Function School of Physiotherapy Dalhousie University Rm 407 4th Floor Forrest Building 5869 University Avenue PO Box 15000 Halifax NS B3H 4R2 Canada. Department of Psychology and Neuroscience Dalhousie University Halifax Canada. PhD Health Program Faculty of Health Dalhousie University Halifax Canada. Neuroplasticity Imagery and Motor Behaviour Laboratory Department of Psychology University of British Columbia Okanagan Campus Vancouver Canada. Laboratory for Brain Recovery and Function School of Physiotherapy Dalhousie University Rm 407 4th Floor Forrest Building 5869 University Avenue PO Box 15000 Halifax NS B3H 4R2 Canada. s.boe@dal.ca. Department of Psychology and Neuroscience Dalhousie University Halifax Canada. s.boe@dal.ca. PhD Health Program Faculty of Health Dalhousie University Halifax Canada. s.boe@dal.ca. School of Health and Human Performance Dalhousie University Halifax Canada. s.boe@dal.ca.

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Construction of dual Z-scheme Ag3VO4–BiVO4/InVO4 photocatalysts using vanadium source from spent catalysts for contaminated water treatment and bacterial inactivation

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Chemosphere 2024年 363卷 142746页

作者： Lee, Kuen-Chan Hsu, Shih-Chieh Huang, Jen-Hsien Wang, Kuan-Syun Pang, Wei Kong Hu, Chih-Wei Jiang, Yi-Jhen Cho, Er-Chieh Weng, Huei Chu Liu, Ting-Yu Department of Science Education National Taipei University of Education No. 134 Sec. 2 Heping E. Road Da-an District Taipei City106 Taiwan PhD Program in Medical Neuroscience College of Medical Science and Technology Taipei Medical University 250 Wuxing Street Taipei City110 Taiwan Department of Chemical and Materials Engineering Tamkang University No. 151 Yingzhuan Road Tamsui District New Taipei City25137 Taiwan Department of Green Material Technology Green Technology Research Institute CPC Corporation No.2 Zuonan Rd. Nanzi District Kaohsiung City81126 Taiwan Department of Materials Engineering Ming Chi University of Technology New Taipei City243303 Taiwan Faculty of Engineering Institute for Superconducting & Electronic Materials University of Wollongong WollongongNSW Australia National Synchrotron Radiation Research Center 101 Hsin-Ann Road Hsinchu Science Park Hsinchu30076 Taiwan School of Pharmacy College of Pharmacy Taipei Medical University 250 Wuxing Street Taipei City110 Taiwan Department of Mechanical Engineering Chung Yuan Christian University No. 200 Chungpei Road Chungli District Taoyuan City32023 Taiwan Department of Chemical Engineering and Materials Science Yuan Ze University Taoyuan City32003 Taiwan College of Engineering & Center for Sustainability and Energy Technologies Chang Gung University Taoyuan33302 Taiwan

Vanadate-based photocatalysts have recently attracted substantial attention owing to their outstanding photocatalytic activity for degrading organic pollutants and generating energy via photocatalytic processes. However, the relatively high price of vanadium has hindered the development of vanadate-based photocatalysts for various applications. Spent catalysts obtained from oil refineries typically contain a significant quantity of vanadium, making them valuable for recovery and utilization as precursors for the production of high-value-added photocatalysts. In this study, we transformed the V present in spent catalysts produced by the petrochemical industry into ternary vanadate-based photocatalysts [BiVO4/InVO4/Ag3VO4 (BVO/IVO/AVO, respectively)] designed for water remediation. The ternary composites revealed an enhanced photocatalytic capability, which was 1.42 and 5.1 times higher than those of the binary BVO/IVO and pristine AVO due to the facilitated charge separation. The ternary photocatalysts not only effectively treated wastewater containing various organic dyes, such as methylene blue (MB), rhodamine 6G (R6G), and brilliant green (BG), but also exhibited remarkable photocatalytic performance in the degradation of antibiotics, reduction of Cr(VI), and bacterial inactivation. This paper proposes a feasible route for recycling industrial waste as a source of vanadium to produce highly efficient vanadate-based photocatalysts. © 2024 Elsevier Ltd

关键词： Water pollution

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Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

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Journal of neuroinflammation 2018年第1期15卷 169页

作者： Megan F Duffy Timothy J Collier Joseph R Patterson Christopher J Kemp Kelvin C Luk Malú G Tansey Katrina L Paumier Nicholas M Kanaan D Luke Fischer Nicole K Polinski Olivia L Barth Jacob W Howe Nishant N Vaikath Nour K Majbour Omar M A El-Agnaf Caryl E Sortwell Department of Translational Science and Molecular Medicine Michigan State University 400 Monroe Avenue NW Grand Rapids MI 49503-2532 USA. Neuroscience Graduate Training Program Michigan State University Grand Rapids MI USA. Mercy Health Hauenstein Neuroscience Medical Center Grand Rapids MI USA. Center for Neurodegenerative Disease Research Department of Pathology and Laboratory Medicine University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Department of Physiology Emory University School of Medicine Atlanta GA USA. MD/PhD Program Michigan State University Grand Rapids MI USA. Neurological Disorders Research Center Qatar Biomedical Research Institute (QBRI) Hamad Bin Khalifa University (HBKU) Education City Qatar. Life Sciences Division College of Science and Engineering Hamad Bin Khalifa University (HBKU) Education City Qatar. Department of Translational Science and Molecular Medicine Michigan State University 400 Monroe Avenue NW Grand Rapids MI 49503-2532 USA. caryl.sortwell@hc.msu.edu. Mercy Health Hauenstein Neuroscience Medical Center Grand Rapids MI USA. caryl.sortwell@hc.msu.edu.

After publication of the original article [1] it was noted that the name of author, D. Luke Fisher, was erroneously typeset in both the PDF and online formats of the manuscript as Luke D. Fisher.

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Correction to: Clinical features and cognitive sequelae in COVID-19: a retrospective study on N=152 patients

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Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2022年第1期43卷 753页

作者： Marina Rita Manera Elena Fiabane Debora Pain Edoardo Nicolò Aiello Alice Radici Marcella Ottonello Mariacristina Padovani Barbara Ann Wilson Jessica Fish Caterina Pistarini Istituti Clinici Scientifici Maugeri IRCCS Psychology Unit of Pavia Institute Pavia Italy. Istituti Clinici Scientifici Maugeri Department of Physical and Rehabilitation Medicine of Genova Nervi Institute Genoa Italy. Istituti Clinici Scientifici Maugeri IRCCS Neurorehabilitation Department of Milano Institute Milan Italy. PhD Program in Neuroscience School of Medicine and Surgery University of Milano-Bicocca Monza Italy. e.aiello5@campus.unimib.it. Department of Clinical Neuropsychology & Clinical Health Psychology St George's University London UK. Institute of Health and Wellbeing University Of Glasgow Glasgow UK. Istituti Clinici Scientifici Maugeri IRCCS Department of Neurorehabilitation of Pavia Institute Pavia Italy.

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