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检索条件"机构=PhD Program of Aging"
257 条 记 录,以下是1-10 订阅
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In Situ Labeling of Pathogenic Tau Using Photo-Affinity Chemical Probes
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ACS CHEMICAL BIOLOGY 2025年 第3期20卷 581-591页
作者: Nie, Pengju Wu, You Robinson, John Mekala, Shekar Lee, Virginia M. Y. Li, Yue-Ming Mem Sloan Kettering Canc Ctr Chem Biol Program New York NY 10065 USA Mem Sloan Kettering Canc Ctr Triinst PhD Program Chem Biol New York NY 10065 USA Univ Penn Inst Aging Dept Pathol & Lab Med Philadelphia PA 19104 USA Univ Penn Ctr Neurodegenerat Dis Res Perelman Sch Med Philadelphia PA 19104 USA
Tau aggregation plays a crucial role in the development of Alzheimer's disease (AD). Developing specific techniques that can isolate pathogenic tau from brain tissue is important for understanding tauopathies and ...
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Rationale and design of a randomized controlled trial evaluating the effects of blueberry consumption versus placebo on brain health in older adults
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CONTEMPORARY CLINICAL TRIALS 2025年 154卷 107926-107926页
作者: Uttke, Zachary Gabriel, Olivia Smith, Ceilidh Guardino, Eric T. Mukamal, Kenneth Djousse, Luc Greater Boston Med Student Aging Res Boston MA USA Brown Univ MD PhD Program Providence RI USA Univ Texas Hlth San Antonio STX MSTP San Antonio TX USA Brigham & Womens Hosp Boston MA USA Beth Israel Deaconess Med Ctr Boston MA USA Harvard Med Sch Boston MA USA Harvard TH Chan Sch Publ Hlth Boston MA USA
Background: Age-related cognitive decline results in significant clinical and public health costs. Cognitive decline predisposes individuals to dementia and leads to difficulties with activities of daily living and in... 详细信息
来源: 评论
Excitatory-inhibitory synaptic imbalance induced by acute intra-hippocampus injections of amyloid-β oligomers
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2025年 742卷 151133页
作者: Arriagada, Jorge Merceron, Daymara Ardiles, Alvaro Munoz, Pablo Paula-Lima, Andrea Univ Chile PhD Program Biomed Sci Santiago Chile Univ Valparaiso Ctr Translat Res Neuropharmacol CITNE Valparaiso Chile Univ Valparaiso Fac Med Med Sch Dept Pathol & Physiol Valparaiso Chile Univ Valparaiso Interuniv Ctr Hlth Aging CIES Valparaiso Chile Univ Chile Inst Res Dent Sci Fac Dent Santiago Chile Univ Chile Biomed Neurosci Inst BNI Fac Med Santiago Chile Univ Chile Fac Med Dept Neurosci Santiago Chile
Alzheimer's disease (AD) is characterized by the accumulation of soluble amyloid-beta oligomers (A beta Os) in the brain, which disrupt synaptic function and promote cognitive decline. Here, we investigated the ef... 详细信息
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Geographic variations in distributions of carbapenemase-encoding genes, susceptibilities, and minimum inhibitory concentrations of inpatient meropenem-resistant Enterobacterales to ceftazidime-avibactam, meropenem-vaborbactam, and aztreonam-avibactam across four global regions: 2020-2022 data from the Antimicrobial Testing Leadership and Surveillance
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INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 2025年 第1期66卷 107500-107500页
作者: Jean, Shio-Shin Lai, Chih-Cheng Ho, Sung-Jung Liu, I-Min Hsieh, Po-Chuen Hsueh, Po-Ren Tajen Univ Dept Pharm Coll Pharm & Hlth Care Pingtung 90741 Taiwan Min Sheng Gen Hosp Dept Internal Med & Crit Care Med Taoyuan Taiwan Chi Mei Med Ctr Div Hosp Med Dept Internal Med Tainan Taiwan Natl Sun Yat Sen Univ Coll Med Sch Med Kaohsiung Taiwan Min Sheng Gen Hosp Dept Internal Med Div Pulm Med Taoyuan Taiwan China Med Univ Hosp China Med Univ Dept Lab Med & Internal Med Taichung Taiwan China Med Univ Sch Med PhD Program Aging Taichung Taiwan China Med Univ Sch Med Dept Lab Med Taichung Taiwan
Purpose: To evaluate the susceptibility profiles of regional inpatient meropenem-resistant (MEM-R) carbapenemase-producing Enterobacterales (CPE) isolates and their MIC values to ceftazidime-avibactam (CZA), meropenem... 详细信息
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Exposure to autoimmune disorders is associated with increased Alzheimer's disease risk in a multi-site electronic health record analysis
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CELL REPORTS MEDICINE 2025年 第3期6卷 101980-101980页
作者: Ramey, Grace D. Tang, Alice Phongpreecha, Thanaphong Yang, Monica M. Woldemariam, Sarah R. Oskotsky, Tomiko T. Montine, Thomas J. Allen, Isabel Miller, Zachary A. Aghaeepour, Nima Capra, John A. Sirota, Marina UCSF Biol & Med Informat PhD Program San Francisco CA USA UCSF Bakar Computat Hlth Sci Inst San Francisco CA 94143 USA UCSF Sch Med San Francisco CA USA Stanford Univ Dept Pathol Palo Alto CA USA Stanford Univ Dept Anesthesiol Perioperat & Pain Med Palo Alto CA USA Stanford Univ Dept Biomed Data Sci Palo Alto CA USA UCSF Dept Med Div Rheumatol San Francisco CA USA UCSF Dept Pediat San Francisco CA 94143 USA UCSF Dept Epidemiol & Biostat San Francisco CA 94143 USA UCSF Memory & Aging Ctr San Francisco CA USA Stanford Univ Dept Pediat Palo Alto CA USA
Autoimmunity has been proposed to increase Alzheimer's disease (AD) risk, but evaluating the clinical connection between autoimmune disorders and AD has been difficult in diverse populations. We investigate risk r... 详细信息
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Social and health disparities associated with healthy brain ageing in Brazil and in other Latin American countries
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LANCET GLOBAL HEALTH 2025年 第2期13卷 e277-e284页
作者: Da Ros, Lucas U. Borelli, Wyllians Vendramini Aguzzoli, Cristiano Schaffer De Bastiani, Marco Antonio Schilling, Lucas Porcello Santamaria-Garcia, Hernando Pascoal, Tharick A. Rosa-Neto, Pedro Souza, Diogo O. da Costa, Jaderson Costa Ibanez, Agustin Suemoto, Claudia Kimie Zimmer, Eduardo R. Univ Fed Rio Grande do Sul Grad Program Biol Sci Biochem Porto Alegre Brazil Univ Fed Rio Grande do Sul Grad Program Biol Sci Biochem Porto Alegre Brazil Univ Fed Rio Grande do Sul Dept Pharmacol BR-90035003 Porto Alegre Brazil Hosp Moinhos Vento Memory Ctr Porto Alegre RS Brazil Pontifical Univ Rio Grande do Sul Brain Inst Rio Grande do Sul Porto Alegre Brazil Pontifical Univ Rio Grande do Sul Sch Med Dept Pediat Tokat Brazil Pontifical Univ Rio Grande do Sul Grad Program Biomed Gerontol Porto Alegre Brazil Univ Calif San Francisco Hosp Univ San Ignacio Ctr Brain & Cognit Intellectus PhD Program NeurosciPontificia Univ Javeriana San Francisco CA USA Univ Calif San Francisco Gobal Brain Hlth Inst Memory & Aging Ctr Francisco CA USA Univ Pittsburgh Dept Psychiat & Neurol Pittsburgh PA USA McGill Ctr Studies Aging Montreal PQ Canada McGill Univ Montreal Neurol Inst Dept Neurol & Neurosurg Montreal PQ Canada Douglas Hosp Res Ctr Montreal PQ Canada Univ Sao Paulo Med Sch Dept Internal Med Div Geriatr Sao Paulo Brazil Univ Adolfo Ibanez Latin Amer Brain Hlth Inst BrainLat Santiago Chile Trinity Coll Dublin Global Brain Hlth Inst Dublin Ireland Univ San Andres Cognit Neurosience Ctr Buenos Aires Argentina
Background Latin American countries present major health-related inequities due to historical, cultural, and social aspects. Recent evidence highlights that factors related to social and health disparities outweigh cl...
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High diversity of strain clonality and metallo-β-lactamases genes among carbapenem-resistant Enterobacterales in Taiwan
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EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 2025年 第2期44卷 251-262页
作者: Lee, Jia-Arng Kuo, Yao-Wen Du, Shin-Hei Lee, Tai-fen Liao, Chun-Hsing Huang, Yu-Tsung Hsueh, Po-Ren Natl Taiwan Univ Coll Med Dept Lab Med Natl Taiwan Univ Hosp Taipei Taiwan Natl Taiwan Univ Grad Inst Clin Lab Sci & Med Biotechnol Taipei Taiwan Natl Taiwan Univ Coll Med Natl Taiwan Univ Hosp Dept Integrated Diagnost & Therapeut Taipei Taiwan Far Eastern Mem Hosp Dept Internal Med New Taipei City Taiwan Natl Yang Ming Univ Coll Med Taipei Taiwan Natl Taiwan Univ Coll Med Dept Internal Med Natl Taiwan Univ Hosp Taipei Taiwan China Med Univ Coll Med PhD Program Aging Taichung Taiwan China Med Univ China Med Univ Hosp Dept Lab Med Taichung Taiwan China Med Univ China Med Univ Hosp Dept Internal Med Taichung Taiwan
PurposeThis study aimed to investigate the genetic and clinical characteristics of carbapenem-resistant Enterobacterales (CRE) isolates carrying metallo-beta-lactamases (MBLs) *** total of 146 non-duplicated isolates ... 详细信息
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A Bite of B Cells: The Potential Role of Bispecific T Cell Engager Therapy (BiTE) in Autoimmune Diseases
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INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES 2025年 第5期28卷 e70252页
作者: Zheng, Jie-Fu Lee, Yung-Heng Kao, Shih-Wen Wei, James Cheng-Chung Tainan Municipal Hosp Dept Internal Med Div Rheumatol & Immunol Tainan Taiwan Minist Hlth & Welf Feng Yuan Hosp Dept Orthoped Kaohsiung Taiwan Natl Sun Yat Sen Univ Inst Med Sci & Technol Kaohsiung Taiwan Minghsin Univ Sci & Technol Dept Sr Serv Ind Management Hsinchu Taiwan Shu Te Univ Dept Recreat & Sport Management Kaohsiung Taiwan Chung Shan Med Univ Hosp Dept Orthopaed Surg Taichung Taiwan Chung Shan Med Univ Sch Med Taichung Taiwan China Med Univ Coll Med PhD Program Aging Taichung Taiwan Chung Shan Med Univ Hosp Dept Allergy Immunol & Rheumatol Taichung Taiwan Chung Shan Med Univ Inst Med Taichung Taiwan Chung Shan Med Univ Dept Nursing Taichung Taiwan China Med Univ Grad Inst Integrated Med Taichung Taiwan
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Impact of extreme weather events on food security among older people: a systematic review
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aging Clinical and Experimental Research 2025年 第1期37卷 1-15页
作者: Nucci, Daniele Pennisi, Flavia Pinto, Antonio De Ponti, Emanuele Ricciardi, Giovanni Emanuele Signorelli, Carlo Veronese, Nicola Castagna, Alberto Maggi, Stefania Cadeddu, Chiara Gianfredi, Vincenza Struttura Semplice Dipartimentale Igiene Alimenti e Nutrizione Dipartimento di Igiene e Prevenzione Sanitaria Agenzia di Tutela della Salute (ATS) Brescia Via Duca degli Abruzzi 15 Brescia 25124 Italy PhD National Program in One Health Approaches to Infectious Diseases and Life Science Research Department of Public Health Experimental and Forensic Medicine University of Pavia Pavia 27100 Italy Faculty of Medicine University Vita-Salute San Raffaele Milan 20132 Italy Faculty of Medicine Saint Camillus International University of Health Sciences Rome Italy Department of Primary Care Health District of Soverato Azienda Sanitaria Provinciale Catanzaro Italy National Research Council (CNR) Aging Section Padova Italy Erasmus School of Health Policy and Management Erasmus University Rotterdam Rotterdam Netherlands Department of Biomedical Sciences for Health University of Milan via Pascal 36 Milan 20133 Italy
Background: Climate change has intensified the frequency and severity of extreme weather events, disproportionately affecting vulnerable populations, including older people for which the literature is still limited. T... 详细信息
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SYSTEMIC CRISIS AND THE NONPROFIT SECTOR - TOWARD A POLITICAL-ECONOMY OF THE NONPROFIT HEALTH AND SOCIAL-SERVICES SECTOR
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THEORY AND SOCIETY 1990年 第2期19卷 173-198页
作者: ESTES, CL ALFORD, RR UNIV CALIF SAN FRANCISCO INST HLTH & AGINGSAN FRANCISCOCA 94143 CUNY PHD PROGRAM SOCIOLNEW YORKNY 10021
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