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CuO NWs boosted triboelectric microfluidic nanosensor functionalized by collagen-protein interactions for real-time platelet count monitoring

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Chemical engineering Journal 2024年 490卷

作者： Lin, Jia-Cheng Kaswan, Kuldeep Chatterjee, Subhodeep Wu, Yu-Wen Kumar Sharma, Manish Ranjan, Ashok Roy Barman, Snigdha Lin, Yu-Zih Burnouf, Thierry Boireau, Wilfrid Lu, Ming-Yen Tu, Yong-Kwang Su, I-Chang Wu, Ping-Hsiu Lin, Zong-Hong Fan, Yu-Jui School of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Taipei Neuroscience Institute Taipei Medical University Taipei11031 Taiwan Department of Biomedical Engineering National Taiwan University Taipei11031 Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu30013 Taiwan Department of Power Mechanical Engineering National Tsing Hua University Hsinchu30013 Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering Taipei Medical University Taipei11031 Taiwan Department of Material Science and Engineering National Tsing Hua University Hsinchu30013 Taiwan Institute of Biomedical Engineering National Tsing Hua University Hsinchu30013 Taiwan International PhD Program in Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Université de Franche-Comté CNRS Institut FEMTO-ST BesançonF-25030 France Department of Neurosurgery Shuang Ho Hospital Taipei Medical University New Taipei City23561 Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Department of Radiology School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Department of Radiation Oncology Taipei Medical University Hospital Taipei11031 Taiwan Center for Precision Health and Quantitative Sciences Taipei Medical University Hospital Taipei 11031 Taiwan

Blood platelet count significantly affects the development of severe conditions like myocardial infarction, peripheral arterial ischemia, respiratory compromise, stroke, diabetes, coronavirus disease 2019 (COVID-19), along with chemotherapy patients and those suffering cardiovascular diseases (CVDs). These conditions necessitate frequent monitoring of platelet counts to guide diagnostic and therapeutic decisions. However, existing techniques are relatively time-consuming, lack of accuracy and require precise operation. The emergence of these severe diseases underscored the need to develop advanced platelet count-monitoring techniques which are rapid, highly precise, and conveniently portable for point-of-care applications. In this study, we emphasized the development of a triboelectric microfluidic nanosensor (TMNS) for platelet quantification through the assessment of flow resistance. The functionality of TMNS device is based on immobilization of platelets on a collagen layer coated inside a microfluidic channel. The triboelectric voltage output is measured as a detection signal of the flow resistance and is enhanced by incorporating high surface area copper oxide nanowires (CuO NWs) on the interior of copper tubes. These copper tubes serve as terminal electrodes and for flow guiding. The flow resistance of plasma solutions is elevated when the platelet concentration increases due to heightened adherence of platelets onto the collagen layer. Variations in flow resistance induce alterations in contact electrification, causing changes in output voltage at load terminals. Fine-tuning of the TMNS device was achieved by optimizing the channel width and length, flowing liquid viscosity, and voltage measurement technique. Platelet quantification sensing data were acquired through the combination of platelet-rich plasma (PRP) and platelet-poor plasma (PPP) solutions. The described device exhibits promising capabilities for platelet-count monitoring in whole-blood samples c

关键词： Copper oxides

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Identification of development of feasibility assessment for community based water power plant 2

Identification of development of feasibility assessment for ...

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2nd International Conference on Computer, Science, engineering, and Technology, ICComSET 2019

作者： Suryadimal Ganefri Ambiyar Jalinus, Nizwardi Rizal, Fahmi Darmayanti, Yeasy Department of Mechanical Engineering Faculty of Industrial Technology Universitas Bung Hatta Padang Indonesia and Phd Eng. Stud. Fac. Eng. Universitas Negeri Padang Indonesia Department of Electrical Engineering Faculty Engineering Universitas Negeri Padang Indonesia Department of Mechanical Engineering Faculty Engineering Universitas Negeri Padang Indonesia Department of Civil Engineering Faculty Engineering Universitas Negeri Padang Indonesia Department of Accountancy Faculty Bisnis and Economic Universitas Bung Hatta Padang Indonesia

This study aims to identify technical and non-technical aspects in developing the feasibility assessment of community-based *** technical aspects consist of the aspects of Hydrology, Civil and mechanical Electrical and non-technical aspects influenced by economic, socio-cultural and environmental aspects. In identifying the two aspects above exploration of Borg and Gall theory, and related studies in the feasibility assessment commonly used by a team of experts and technical consultants and government *** feasibility assessment is strongly influenced by 43.24% of technical and non-technical aspects, the relationship between hydraulics and economic aspects ranges 32.43%, and the influence of social and environmental aspects by 24.32% © 2020 Published under licence by IOP Publishing Ltd.

关键词： Hydraulics

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Emergence of Non-photoresponsive Catalytic Techniques for Environmental Remediation and Energy Generation

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Chemistry - An Asian Journal 2023年第9期18卷 e202300090页

作者： Kumar Sharma, Manish Khan, Imran Kaswan, Kuldeep Roy Barman, Snigdha Saha, Subhajit Hsieh, Wu-Chiao Chueh, Yu-Lun Wang, Yu-Lin Lee, Sangmin Choi, Dukhyun Lin, Zong-Hong Department of Materials Science and Engineering National Tsing Hua University Hsinchu30013 Taiwan Institute of NanoEngineering and Microsystems National Tsing Hua University Hsinchu30013 Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu30013 Taiwan Department of Renewable Energy Maulana Abul Kalam Azad University of Technology West Bengal741249 India Department of Obstetrics and Gynecology Chang Gung Memorial Hospital and College of Medicine Chang Gung University Taoyuan333 Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan School of Mechanical Engineering Chung-Ang University Seoul06974 Korea Republic of Department of Mechanical Engineering Sungkyunkwan University Suwon16419 Korea Republic of Department of Biomedical Engineering National Taiwan University Taipei10617 Taiwan

Catalysis plays a crucial role in all the major applications and challenges in the environment, including energy generation and environmental remediation. Although photocatalysts and electrocatalysts are useful in addressing energy and environmental issues, they have some major drawbacks, such as low efficiency and easy charge recombination which limits their applications. Hence, it is imperative to design and explore new catalytic techniques that include non-photoresponsive catalysts. In this review, the detailed possibilities, characteristics and prospects of non-photoresponsive catalysts, such as piezocatalysts, thermocatalysts, pyrocatalysts, and tribocatalysts along with hybrid catalysts are described. The overall mechanism of each catalytic technique and its applications in different fields such as energy generation, environmental remediation, and carbon dioxide reduction are discussed. © 2023 Wiley-VCH GmbH.

关键词： Electrocatalysts

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Predicting biocrude oil yields from hydrothermal liquefaction of an energy grass: Machine learning approach and experimental validation

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AIP Conference Proceedings 2024年第1期3236卷

作者： Tossapon Katongtung Nakorn Tippayawong Graduate PhD Degree Program in Energy Engineering Faculty of Engineering Chiang Mai University Chiang Mai 50200 Thailand Department of Mechanical Engineering Faculty of Engineering Chiang Mai University Chiang Mai 50200 Thailand

In recent years, our world has been grappling with the challenges of global warming, prompting a search for alternative energy sources that can provide clean and sustainable power without adversely impacting the environment. Biomass has emerged as a viable option due to its potential as a renewable and environmentally friendly energy source. Among various processes available, hydrothermal liquefaction (HTL) has gained significant attention for its capability of converting wet biomass into biocrude oil in a relatively short timeframe. Previous studies have explored integration of machine learning with HTL to forecast the yields of biocrude oil. This work aims to develop a machine learning model specifically tailored to predicting the biocrude oil yields from the HTL process. Furthermore, experiments were done using Napier 4190 (Giant Juncao Grass) as a biomass source to verify the accuracy of this machine learning model. The findings revealed that the machine learning model achieved an R2 value of approximately 0.8. Model predictions and experimental results show a discrepancy of approximately 6-14%.

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Shape-Tunable BaTiO3 Crystals Presenting Facet-Dependent Optical and Piezoelectric Properties

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Small 2023年第9期19卷 2205920-2205920页

作者： Chen, Jing-Wei Pal, Arnab Chen, Bo-Hao Kumar, Gautam Chatterjee, Subhodeep Peringeth, Kiran Lin, Zong-Hong Huang, Michael H. Department of Chemistry National Tsing Hua University Hsinchu300044 Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu300044 Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu300044 Taiwan National Synchrotron Radiation Research Center Hsinchu300092 Taiwan Department of Power Mechanical Engineering National Tsing Hua University Hsinchu300044 Taiwan Institute of Biomedical Engineering National Tsing Hua University Hsinchu300044 Taiwan

BaTiO3 octahedra, edge-, and corner-truncated cubes, and cubes with four tunable sizes from 132 to 438 nm are synthesized by a solvothermal growth approach. Acetic acid treatment can cleanly remove BaCO3 impurity. Rietveld refinement of X-ray diffraction patterns and Raman spectra help to confirm the particles have a tetragonal crystal structure. The crystals also exhibit size- and facet-dependent bandgap shifts. BaTiO3 octahedra show larger piezoelectric, ferroelectric, and pyroelectric effects than truncated cubes and cubes. The measured dielectric constant differences should be associated with their various facet-dependent behaviors. Piezoelectric nanogenerators fabricated from BaTiO3 octahedra consistently show the best performance than those containing truncated cubes and cubes. In particular, a nanogenerator with 30 wt.%-incorporated octahedra displays an open-circuit voltage of 23 V and short-circuit current of 324 nA. The device performance is also highly stable. The maximum output power reaches 3.9 µW at 60 MΩ. The fabricated nanogenerator can provide sufficient electricity to power light-emitting diodes. This work further demonstrates that various physical properties of semiconductor crystals show surface dependence. © 2022 Wiley-VCH GmbH.

关键词： Piezoelectricity

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Selection of tool transverse speed considering trial run experimentations for AZ61/Tic composite developed via friction stir processing using triangular tool

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Materials Today: Proceedings 2021年 38卷 198-203页

作者： P. Sagar A. Handa PhD Research scholar I.K. Gujral Punjab Technical University Kapurthala India Department of Mechanical Engineering I.K. Gujral Punjab Technical University Kapurthala India

In this present work, an effort has been applied to fabricated AZ61/TiC magnesium based metal matrix composite. The effect of tool transverse speed and specimen holding time after etchant application has been studied before final design and run of experiments. A set of zig-zag holes were prepared into the 200 mm × 100 mm × 6 mm thick AZ61A plate and compacted with TiC particles. A fixed three pass Friction stir processing (FSP) was performed out employing a fixed tool rotation speed of 850 rpm and varying tool transverse speed of 25 mm/min, 100 mm/min and 170 mm/min. Optical microscopy (OM) was used to study the grain refinement. The results indicate that for tool rotational speed of 850 rpm and transverse speed of 25 mm/min better grains were formed at stir zone (SZ) and poor grains were observed once the specimen analyzed after 25 min of etching.

关键词： Friction stir processing Magnesium base Alloy TiC Optical Microscopy Grain refinement

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Heat treatment analysis of SS304 for gas turbine application

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Materials Today: Proceedings 2020年 33卷 5734-5739页

作者： Kamal Kumar Pradhan Chhabi Ram Matawale PhD Scholar Department of Mechanical Engineering Shri Rawatpura Sarkar University Raipur Chhattisgarh India Associate Professor Department of Mechanical Engineering Head Faculty of Engineering Shri Rawatpura Sarkar University Raipur Chhattisgarh India

With the highly increasing demand of Ni/Cr based austenitic stainless steel grade 304, due to its high corrosion resistance , high ductility, excellent weldability and cost effective material, but low strength and hardness limit its application. The investigation on stainless steel grade 304 was performed for the gas turbine application. As in gas turbine, material must have high corrosion resistance & high strength and hardness. To improve the material properties heat treatment, full annealing process were adopted because of the micro-structural grain refinement occurrence during the process. The annealing process was performed at temperature 1010 °C &1120 °C and the properties such as hardness and tensile strength were tested with heat treated as well as without heat treated SS304 specimen materials. The test results shows that heat treated specimens have much better property than without heat treated specimen. Most of the properties of heat treated specimens are nearer and some properties are better than the present materials used as gas turbine materials such as IN706 alloy, IN718 alloy, A-286 alloy, RENE95 alloy, which shows applicability of SS304 as gas turbine materials.

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A triboelectric nanogenerator-based tactile sensor array system for monitoring pressure distribution inside prosthetic limb

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Nano Energy 2023年 111卷

作者： Chang, Kuie-Bin Parashar, Parag Shen, Li-Chien Chen, An-Rong Huang, Yan-Tsz Pal, Arnab Lim, Kee-Chin Wei, Po-Han Kao, Fu-Cheng Hu, Jin-Jia Lin, Zong-Hong Department of Mechanical Engineering National Yang Ming Chiao Tung University Hsinchu Taiwan Department of Biomedical Engineering National Taiwan University Taipei Taiwan Department of Material Science and Engineering National Tsing Hua University Hsinchu Taiwan Institute of Biomedical Engineering National Tsing Hua University Hsinchu Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu Taiwan Department of Orthopaedic Surgery Chang Gung Memorial Hospital Taoyuan Taiwan College of Medicine Chang Gung University Taoyuan Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan

In the prosthetic field, quantifying interfacial pressure distribution between the amputee's residual limb and the socket's internal environment is imperative for developing new technologies. However, the commercially available pressure sensors have several disadvantages, namely external power supply requirements, low stability, high cost, and complexities related to integrating the sensor system into prosthetic devices. Herein, we propose a self-powered triboelectric nanogenerator (TENG) based flexible tactile sensor array system to monitor prosthetic socket internal pressure distribution in real-time. The proposed sensor consists of biocompatible polydimethylsiloxane (PDMS) polymer and polycaprolactone (PCL) nanofiber membranes as triboelectric materials. The biodegradable PCL nanofiber membrane, fabricated via a scalable and cost-effective electrospinning process, possesses a high surface area-to-volume ratio, facilitating enhanced charge generation during triboelectrification. The as-fabricated TENG-based tactile sensor is highly stable up to 10,000 cycles. Furthermore, the voltage of the tactile sensor is independent of different temperature and humidity values, demonstrating the stability of the sensor under various environmental conditions. Finally, we successfully integrated the tactile sensor array within a prosthetic device to monitor real-time pressure distribution inside the prosthetic socket during gait simulation. We believe that the proposed novel design provides a new dimension for the rapid development of self-powered, low-cost, and highly stable pressure monitoring systems with considerable potential for commercialization. © 2023 Elsevier Ltd

关键词： Electrospinning

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In vitro evaluation and comparison of the abrasive capacity of zirconia whitening toothpaste at different concentrations on the radicular dentin surface of human teeth

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Heliyon 2025年第3期11卷 e41867页

作者： Stavileci, Miranda Pustina, Teuta Salihu, Besir Veronneau, Jacques Bajrami, Xhevahir Gjelaj, Afrim Department of Dental Pathology and Endodontics Medical Faculty University of Prishtina “Hasan Prishtina” Prishtina Serbia Department of Prosthodontics Medical Faculty University of Prishtina “Hasan Prishtina” Prishtina Serbia University of Prishtina “Hasan Prishtina” Faculty of Medicine PhD Student at Public Health Department Prishtina Serbia Centres Dentaires Véronneau Quebec Canada Faculty of Mechanical Engineering University of Prishtina “Hasan Prishtina” Prishtina Serbia

Background: Marketed toothpastes vary in the extent to how much abrasive wear they cause to dentin. New abrasive particles in a dentifrice should be evaluated since there they can be at risk of abrasion to dentin and root surfaces. Aim: The aim of this in vitro study was to evaluate abrasive dentin wear and surface roughness after brushing with whitening toothpaste containing zirconia at four different concentrations. Material and method: This study tested 40 extracted human teeth. After crown removal, root dentin samples were randomly divided into four experimental groups based on zirconia toothpaste concentration: Group A (10 samples) brushed for 5 min with 0.5 % zirconia toothpaste, Group B (10 samples) with 1 %, Group C (10 samples) with 2 %, and the last 10 samples with 5 %. Before brushing, specimens were weighed three times using a precision analytical scale and measured with a Profile Projector. After completing the brushing cycles, surface roughness was measured to evaluate the differences after brushing. Results: The Kruskal-Wallis test showed no significant difference in the weight of samples at 0.5 %, 1 %, and 2 % toothpaste concentrations. However, at the 5 % toothpaste concentration, there was a significant difference in sample weight measurements (P < 0.05). The mean roughness difference in the three lower concentrations indicated no significant statistical difference, but with the 5 % toothpaste, there was an increase in average dentin roughness (P < 0.05). Conclusion: Results showed that percentage ≤2.0 % of zirconium powder added in a toothpaste, can lead to dentin minimal wear and better roughness by polishing effect. Toothpaste containing 5 % zirconia showed an abrasive effect on dentin and increased surface roughness. © 2025 The Authors

关键词： Dentin Roughness Tooth wear Toothpaste Zirconia

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An Adaptive Multi-critic Neuro-fuzzy Control Framework for Intravenous Anesthesia Administration

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IFAC-PapersOnLine 2019年第34期51卷 202-207页

作者： Khodaei, Mohammad Javad Balaghi I., M. Hadi Mehrvarz, Amin Jalili, Nader PhD Student Piezoactive Systems Laboratory Department of Mechanical Industrial Engineering Northeastern University BostonMA02115 United States Eindhoven Netherlands Professor and Author of Correspondence Department Head of Mechanical Engineering The University of Alabama TuscaloosaAL United States Affiliate Professor Department of Mechanical Industrial Engineering Northeastern University BostonMA United States

Development of closed-loop control strategies for drug infusion and delivery is one of the most recent efforts of control engineers and clinicians. This can be used especially in anesthesia during different surgeries to stabilize the patient in the desired awareness condition. In this paper, an adaptive neuro-fuzzy controller is proposed to overcome the current challenges in closed-loop control of anesthesia such as inter and intra patient variability, complex and nonlinear dynamics, measurement noises and surgical disturbances as well as the presence of undershoot and overshoot in the induction phase. The results show an acceptable performance of the proposed controller in solving these problems by providing a learning scheme. © 2019

关键词： Controllers Anesthesiology Closed loop control systems Controlled drug delivery Drug infusion Fuzzy control Fuzzy inference Fuzzy neural networks Surgery Closed loops Fuzzy controllers Inter intra patient variability Intravenous anesthesias Surgical disturbances

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