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Erratum for Wang et al., "Clinically Applicable System for Rapidly Predicting Enterococcus faecium Susceptibility to Vancomycin"

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Microbiology spectrum 2022年第1期10卷 e0261021页

作者： Hsin-Yao Wang Chia-Ru Chung Chao-Jung Chen Ko-Pei Lu Yi-Ju Tseng Tzu-Hao Chang Min-Hsien Wu Wan-Ting Huang Ting-Wei Lin Tsui-Ping Liu Tzong-Yi Lee Jorng-Tzong Horng Jang-Jih Lu Department of Laboratory Medicine Chang Gung Memorial Hospitalgrid.413801.f at Linkou Taoyuan City Taiwan. Ph.D. Program in Biomedical Engineering Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Computer Science and Information Engineering National Central Universitygrid.37589.30 Taoyuan City Taiwan. Graduate Institute of Integrated Medicine China Medical Universitygrid.254145.3 Taichung Taiwan. Proteomics Core Laboratory China Medical Universitygrid.254145.3 Hospital Taichung Taiwan. Graduate Program in Biomedical Information Yuan-Ze University Taoyuan City Taiwan. Department of Information Management Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Graduate Institute of Biomedical Informatics Taipei Medical University Taipei City Taiwan. Clinical Big Data Research Center Taipei Medical University Hospital Taipei City Taiwan. Graduate Institute of Biomedical Engineering Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Division of Haematology/Oncology Department of Internal Medicine Chang Gung Memorial Hospitalgrid.413801.f at Linkou Taoyuan City Taiwan. Biosensor Group Biomedical Engineering Research Center Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Pathology Kaohsiung Chang Gung Memorial Hospitalgrid.413801.f and Chang Gung University College of Medicine Kaohsiung Taiwan. School of Life and Health Sciences The Chinese University of Hong Kong Shenzhen China. Warshel Institute for Computational Biology The Chinese University of Hong Kong Shenzhen China. Department of Bioinformatics and Medical Engineering Asia University Taichung City Taiwan. School of Medicine Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Medical Biotechnology and Laboratory Science Chang Gung Universitygrid.145695.a Taoyuan City Taiwan.

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Metasurfaces: Coherent Perfect Diffraction in Metagratings (Adv. Mater. 36/2020)

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Advanced Materials 2020年第36期32卷

作者： Ziying Zhang Ming Kang Xueqian Zhang Xi Feng Yuehong Xu Xieyu Chen Huifang Zhang Quan Xu Zhen Tian Weili Zhang Alex Krasnok Jiaguang Han Andrea Alù Center for Terahertz Waves College of Precision Instrument and Optoelectronics Engineering Key Laboratory of Optoelectronics Information and Technology Tianjin University Tianjin 300072 P. R. China Department of Electrical and Computer Engineering The University of Texas at Austin Austin TX 78712 USA School of Electrical and Computer Engineering Oklahoma State University Stillwater OK 74078 USA Photonics Initiative Advanced Science Research Center City University of New York New York NY 10031 USA Physics Program Graduate Center City University of New York New York NY 10016 USA

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All-optical reconfigurable chiral meta-molecules

arXiv

引用

arXiv 2019年

作者： Lin, Linhan Lepeshov, Sergey Krasnok, Alex Jiang, Taizhi Peng, Xiaolei Korgel, Brian A. Alu, Andrea Zheng, Yuebing Department of Mechanical Engineering University of Texas at Austin AustinTX78712 United States Materials Science & Engineering Program Texas Materials Institute University of Texas at Austin AustinTX78712 United States ITMO University St. Petersburg197101 Russia Department of Electrical and Computer Engineering University of Texas at Austin AustinTX78712 United States Mc Ketta Department of Chemical Engineering University of Texas at Austin AustinTX78712 United States Photonics Initiative Advanced Science Research Center City University of New York New YorkNY10031 United States Physics Program Graduate Center City University of New York NY10016 United States Department of Electrical Engineering City College of The City University New YorkNY10031 United States

Chirality is a ubiquitous phenomenon in the natural world. Many biomolecules without inversion symmetry such as amino acids and sugars are chiral molecules. Measuring and controlling molecular chirality at a high precision down to the atomic scale are highly desired in physics, chemistry, biology, and medicine, however, have remained challenging. Herein, we achieve all-optical reconfigurable chiral meta-molecules experimentally using metallic and dielectric colloidal particles as artificial atoms or building blocks to serve at least two purposes. One is that the on-demand meta-molecules with strongly enhanced optical chirality are well-suited as substrates for surface-enhanced chiroptical spectroscopy of chiral molecules and as active components in optofluidic and nanophotonic devices. The other is that the bottom-up-assembled colloidal meta-molecules provide microscopic models to better understand the origin of chirality in the actual atomic and molecular systems. Copyright © 2019, The Authors. All rights reserved.

关键词： Atoms

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Machine learning for early prediction of circulatory failure in the intensive care unit

arXiv

引用

arXiv 2019年

作者： Hyland, Stephanie L. Faltys, Martin Hüser, Matthias Lyu, Xinrui Gumbsch, Thomas Esteban, Cristóbal Bock, Christian Horn, Max Moor, Michael Rieck, Bastian Zimmermann, Marc Bodenham, Dean Borgwardt, Karsten Rätsch, Gunnar Merz, Tobias M. Department of Computer Science ETH Zürich Zürich Switzerland Computational Biology Program Memorial Sloan Kettering Cancer Center New York United States Tri-Institutional PhD Program in Computational Biology and Medicine Weill Cornell Medicine New York United States Medical Informatics Group Zürich University Hospital Zürich Switzerland Department of Intensive Care Medicine University Hospital University of Bern Bern Switzerland Department of Biosystems and Engineering ETH Zürich Basel Switzerland Department of Biology ETH Zürich Zürich Switzerland Swiss Institute for Bioinformatics Lausanne Switzerland Cardiovascular Intensive Care Unit Auckland City Hospital Auckland New Zealand

Intensive care clinicians are presented with large quantities of patient information and measurements from a multitude of monitoring systems. The limited ability of humans to process such complex information hinders physicians to readily recognize and act on early signs of patient deterioration. We used machine learning to develop an early warning system for circulatory failure based on a high-resolution ICU database with 240 patient-years of data. This automatic system predicts 90.0% of circulatory failure events (prevalence 3.1%), with 81.8% identified more than two hours in advance, resulting in an area under the receiver operating characteristic curve of 94.0% and area under the precision recall curve of 63.0%. The model was externally validated in a large independent patient cohort. Copyright © 2019, The Authors. All rights reserved.

关键词： Intensive care units

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FINDING CONTINUITY AND DISCONTINUITY IN FISH SCHOOLS VIA INTEGRATED INFORMATION THEORY

arXiv

引用

arXiv 2018年

作者： Niizato, Takayuki Sakamoto, Kotaro Mototake, Yoh-ichi Murakami, Hisashi Tomaru, Takenori Hoshika, Tomotaro Fukushima, Toshiki Faculty of Engineering Information and Systems University of Tsukuba Japan Human Biology Program University of Tsukuba Japan Graduate School of Frontier Sciences University of Tokyo Japan Research Center for Advanced Science and Technology University of Tokyo Japan Department of Computer Science and Engineering Toyohashi University of Technology Japan

Collective behaviour is known to be the result of diverse dynamics and is sometimes likened to a living system. Although many studies have revealed the dynamics of various collective behaviours, their main focus was on the information process inside the collective, not on the whole system itself. For example, the qualitative difference between two elements and three elements as a system has rarely been investigated. Tononi et al. have proposed Integrated Information Theory (IIT) to measure the degree of consciousness Φ. IIT postulates that the amount of information loss caused by certain partitions is equivalent to the degree of information integration in the system. This measure is not only useful for estimating the degree of consciousness but can also be applied to more general network systems. Here we applied IIT (in particular, IIT 3.0 using PyPhi) to analyse real fish schools (Plecoglossus altivelis). Our hypothesis in this study is a very simple one: a living system evolves to raise its Φ value. If we accept this hypothesis, IIT reveals the existence of continuous and discontinuous properties as group size varies. For example, leadership in the fish school emerged for a school size of four or above;but not below three. Furthermore, this transition was not observed by measuring mutual information or in a simple Boids model. This result suggests that integrated information Φ can reveal some inherent properties which cannot be observed using other measures. We also discuss how the fish recognition of the figure-ground relation, that is, what determines the relevant ON and OFF states, may reveal various optimal paths for obtaining the functional evolution of collective behaviour. Copyright © 2018, The Authors. All rights reserved.

关键词： Information theory

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98 Moberas: a mobile app to monitor and motivate gynecological oncology (GYO) patients to adhere to eras protocol

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International Journal of Gynecological Cancer 2019年 29卷 A50-A50页

作者： A. Santiago W. Brandão V. Cruz A. Silva Filho PhD student Post-Graduate Program in Gynecology- Obstetrics and Mastology of UNESP Botucatu Brazil Pontifícia Universidade Católica de Minas Gerais Department of Computer Science Belo Horizonte Brazil Universidade Federal de Minas Gerais Department of Gynecology and Obstetrics Belo Horizonte Brazil

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TOI-2015 b: a sub-Neptune in strong gravitational interaction with an outer non-transiting planet

arXiv

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arXiv 2025年

作者： Barkaoui, K. Korth, J. Gaidos, E. Agol, E. Parviainen, H. Pozuelos, F.J. Palle, E. Narita, N. Grimm, S. Brady, M. Bean, J.L. Morello, G. Rackham, B.V. Burgasser, A.J. Van Grootel, V. Rojas-Ayala, B. Seifahrt, A. Marfil, E. Passegger, V.M. Stalport, M. Gillon, M. Collins, K.A. Shporer, A. Giacalone, S. Yalçınkaya, S. Ducrot, E. Timmermans, M. Triaud, A.H.M.J. de Wit, J. Soubkiou, A. Watkins, C.N. Aganze, C. Alonso, R. Amado, P.J. Basant, R. Baştürk, Ö. Benkhaldoun, Z. Burdanov, A. Calatayud-Borras, Y. Chouqar, J. Conti, D.M. Collins, K.I. Davoudi, F. Delrez, L. Dressing, C.D. de Leon, J. Dévora-Pajares, M. Demory, B.O. Dransfield, G. Esparza-Borges, E. Fernández-Rodriguez, G. Fukuda, I. Fukui, A. Gallardo, P.P.M. Garcia, L. Garcia, N.A. Ghachoui, M. Geraldía-González, S. Chew, Y. Gómez Maqueo González-Rodríguez, J. Günther, M.N. Hayashi, Y. Horne, K. Hooton, M.J. Hsu, C.C. Ikuta, K. Isogai, K. Jehin, E. Jenkins, J.M. Kawauchi, K. Kagetani, T. Kawai, Y. Kasper, D. Kielkopf, J.F. Klagyivik, P. Lacedelli, G. Latham, D.W. Libotte, F. Luque, R. Livingston, J.H. Mancini, L. Massey, B. Mori, M. Torres, S. Muñoz Murgas, F. Niraula, P. Orell-Miquel, J. Rapetti, David Rebolo-López, R. Ricker, G. Papini, R. Pedersen, P.P. Peláez-Torres, A. Pérez-Prieto, J.A. Poultourtzidis, E. Rodriguez, P.M. Queloz, D. Savel, A.B. Schanche, N. Sánchez-Benavente, M. Sibbald, L. Sefako, R. Sohy, S. Sota, A. Schwarz, R.P. Seager, S. Sebastian, D. Southworth, J. Stangret, M. Stefánsson, G. Stürmer, J. Srdoc, G. Thompson, S.J. Terada, Y. Vanderspek, R. Wang, G. Watanabe, N. Wilkin, F.P. Winn, J. Wells, R.D. Ziegler, C. Zúñiga-Fernández, S. Astrobiology Research Unit Université de Liège Allée du 6 Août 19C LiègeB-4000 Belgium Department of Earth Atmospheric and Planetary Science Massachusetts Institute of Technology 77 Massachusetts Avenue CambridgeMA02139 United States Calle Vía Láctea s/n Tenerife La Laguna38200 Spain Lund Observatory Division of Astrophysics Department of Physics Lund University Box 118 Lund22100 Sweden Department of Earth Sciences University of Hawaii at Manoa 1680 East-West Rd HonoluluHI96822 United States Institute for Astrophysics University of Vienna Türkenschanzstrasse 17 ViennaA-1180 Austria Department of Astronomy Astrobiology Program University of Washington Box 351580 SeattleWA98195 United States NExSS Virtual Planetary Laboratory University of Washington Box 351580 SeattleWA98195 United States Tenerife La LagunaE-38206 Spain Glorieta de la Astronomía s/n Granada18008 Spain INAF- Palermo Astronomical Observatory Piazza del Parlamento 1 Palermo90134 Italy Komaba Institute for Science The University of Tokyo 3-8-1 Komaba Meguro Tokyo153-8902 Japan Astrobiology Center 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Research Institute for Advanced Computer Science Universities Space Research Association WashingtonDC20024 United States Institute for Particle Physics and Astrophysics ETH Zürich OttoStern-Weg 5 Zürich8093 Switzerland Department of Astrophysics University of Zürich Winterthurerstrasse 190 Zürich8057 Switzerland Department of Astronomy & Astrophysics University of Chicago ChicagoIL United States NHFP Sagan Fellow United States Department of Physics Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA02139 United States Institute Université de Liège Allée du 6 Août 19C LiègeB-4000 Belgium Instituto de Alta Investigación Universidad de Tarapacá Casilla 7D Arica Chile Gemini Observatory NSF NOIRLab 670 N. A’ohoku Place HiloHI96720 United States Departamento de

TOI-2015 is a known exoplanetary system around an M4 dwarf star, consisting of a transiting sub-Neptune planet in a 3.35-day orbital period, TOI-2015 b, accompanied by a non-transiting companion, TOI-2015 c. High-precision radial velocity measurements were taken with the MAROON-X spectrograph, and high-precision photometric data were collected, primarily using the SPECULOOS, MUSCAT, TRAPPIST and LCOGT networks. We collected 63 transit light curves and 49 different transit epochs for TOI-2015 b. We re-characterize the target star by combining optical spectra obtained by the MAROON-X, Shane/KAST and IRTF/SpeX spectrographs, Bayesian Model Averaging (BMA) and Spectral Energy Distribution (SED) analysis. The TOI-2015 host star is a K = 10.3 mag M4-type dwarf with a sub-solar metallicity of [e/H]= −0.31 ± 0.16, and an effective temperature of Teff ≈ 3200 K. Our photodynamical analysis of the system strongly favors the 5:3 mean motion resonance and in this scenario the planet b (TOI-2015 b) has an orbital period of Pb = 3.34 days, a mass of Mp = 9.02+0.32−0.36 M⊗, a radius of Rp = 3.309+0.013−0.11 R⊗, resulting in a density of ρp = 0.25±0.01 ρ⊗ = 1.40±0.06 g cm−3, indicative of a Neptune-like composition. Its transits exhibit large (> 1 hr) timing variations indicative of an outer perturber in the system. We performed a global analysis of the high-resolution radial-velocity measurements, the photometric data, and the TTVs, and inferred that TOI-2015 hosts a second planet, TOI-2015 c, in a non-transiting configuration. Our analysis places it near a 5:3 resonance with an orbital period of Pc = 5.583 days and a mass of Mp = 8.91+0.38−0.40 M⊗. The dynamical configuration of TOI-2015 b and TOI-2015 c can be used to constrain the system’s planetary formation and migration history. Based on the mass-radius composition models, TOI-2015 b is a water-rich or rocky planet with a hydrogen-helium envelope. Moreover, TOI-2015 b has a high transmission spectroscopic metric (TSM= 149), m

关键词： Stars

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Author Correction: Proteogenomic landscape of human pancreatic ductal adenocarcinoma in an Asian population reveals tumor cell-enriched and immune-rich subtypes

Nature cancer

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Nature cancer 2023年 2023 May 19页

作者： Do Young Hyeon Dowoon Nam Youngmin Han Duk Ki Kim Gibeom Kim Daeun Kim Jingi Bae Seunghoon Back Dong-Gi Mun Inamul Hasan Madar Hangyeore Lee Su-Jin Kim Hokeun Kim Sangyeop Hyun Chang Rok Kim Seon Ah Choi Yong Ryoul Kim Juhee Jeong Suwan Jeon Yeon Woong Choo Kyung Bun Lee Wooil Kwon Seunghyuk Choi Taewan Goo Taesung Park Young-Ah Suh Hongbeom Kim Ja-Lok Ku Min-Sik Kim Eunok Paek Daechan Park Keehoon Jung Sung Hee Baek Jin-Young Jang Daehee Hwang Sang-Won Lee School of Biological Sciences Seoul National University Seoul Republic of Korea. Department of Chemistry and Center for Proteogenome Research Korea University Seoul Republic of Korea. Department of Surgery and Cancer Research Institute Seoul National University College of Medicine Seoul Republic of Korea. Department of Anatomy and Cell Biology and Department of Biomedical Sciences Seoul National University College of Medicine Seoul Republic of Korea. Graduate School of Medical Science and Engineering Korea Advanced Institute of Science and Technology (KAIST) Seoul Republic of Korea. Creative Research Initiatives Center for Epigenetic Code and Diseases Seoul National University Seoul Republic of Korea. Department of Biological Sciences College of Natural Sciences and Department of Molecular Science and Technology Ajou University Suwon Republic of Korea. Department of Pathology Seoul National University College of Medicine Seoul Korea. Department of Computer Science Hanyang University Seoul Republic of Korea. Interdisciplinary Program in Bioinformatics Seoul National University Seoul Republic of Korea. Department of Statistics Seoul National University Seoul Republic of Korea. Korean Cell Line Bank Laboratory of Cell Biology Cancer Research Institute Seoul National University College of Medicine Seoul Korea. Department of New Biology Daegu Gyeongbuk Institute of Science and Technology Daegu Republic of Korea. Department of Biological Sciences College of Natural Sciences and Department of Molecular Science and Technology Ajou University Suwon Republic of Korea. dpark@ajou.ac.kr. Department of Anatomy and Cell Biology and Department of Biomedical Sciences Seoul National University College of Medicine Seoul Republic of Korea. keehoon.jung@snu.ac.kr. Institute of Allergy and Clinical Immunology Seoul National University Medical Research Center Seoul Republic of Korea. keehoon.jung@snu.ac.kr. School of Biological Sciences Seoul National University Seoul Republic of

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Combination of curcumin or chitosan with photodynamic therapy as an effective alternative therapy for overcoming wound infection associated with multidrug-resistant Acinetobacter baumannii

Microbe (Netherlands)

引用

Microbe (Netherlands) 2025年 7卷

作者： Yonpiam, Manta Wannigama, Dhammika Leshan Shein, Aye Mya Sithu Liao, Tingting Hurst, Cameron Monk, Peter N. Amarasiri, Mohan Phattharapornjaroen, Phatthranit Ounjai, Puey Saethang, Thammakorn Badavath, Vishnu Nayak Luk-in, Sirirat Nilgate, Sumanee Rirerm, Ubolrat Srisakul, Sukrit Ngamwongsatit, Natharin Leelahavanichkul, Asada Ragupathi, Naveen Kumar Devanga Kanjanabuch, Talerngsak Narkban, Phurin Miyanaga, Kazuhiko Cui, Longzhu Boontaveeyuwat, Einapak Higgins, Paul G. Kicic, Anthony Hamamoto, Hiroshi Abe, Shuichi Hongsing, Parichart Chatsuwan, Tanittha Department of Microbiology Faculty of Medicine Chulalongkorn University King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand Center of Excellence in Antimicrobial Resistance and Stewardship Research Faculty of Medicine Chulalongkorn University Bangkok Thailand Dual degree Medical Science program Faculty of Medicine Chulalongkorn University Bangkok 10330 Thailand Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan School of Medicine Faculty of Health and Medical Sciences The University of Western Australia Nedlands WA Australia Biofilms and Antimicrobial Resistance Consortium of ODA receiving countries The University of Sheffield Sheffield United Kingdom Pathogen Hunter's Research Team Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan Department of Infectious Diseases Faculty of Medicine Yamagata University Yamagata Japan Department of Clinical Epidemiology Faculty of Medicine Thammasat University Rangsit 10120 Thailand Department of Infection Immunity & Cardiovascular Disease University of Sheffield Medical School United Kingdom Department of Civil and Environmental Engineering Graduate School of Engineering Tohoku University Miyagi Japan Faculty of Health Science Technology Chulabhorn Royal Academy Bangkok 10210 Thailand HRH Princess Chulabhorn Disaster and Emergency Medicine Center Chulabhorn Royal Academy Bangkok 10210 Thailand Department of Biology Faculty of Science Mahidol University Bangkok Thailand Department of Computer Science Faculty of Science Kasetsart University Bangkok Thailand School of Pharmacy & Technology Management SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Hyderabad 509301 India Department of Clinical Microbiology and Applied Technology Faculty of Medical Technology Mahidol University Bangkok Thailand Department of Clinical Sciences and Public Health Faculty of Veteri

The increasing prevalence of multidrug-resistant Acinetobacter baumannii as an opportunistic pathogen in wound infections raises significant concerns due to its antibiotic resistance and biofilm-mediated antibiotic tolerance. This underscores the urgent need to explore an alternative approach to effectively managing wound infections caused by MDR A. baumannii. In this study, combining subinhibitory concentrations of curcumin (25 µg/ml) or chitosan (156 µg/ml) with photodynamic therapy-PDT (10 J/cm²) resulted in a significant reduction of planktonic viabilities and biofilm biovolume of MDR A. baumannii clinical isolates in vitro. In murine A. baumannii-associated wound infection, a combination of curcumin (25 µg/ml) or chitosan (156 µg/ml) with PDT (10 J/cm²) resulted in complete bacterial eradication with wound healing at Day 15 of post-treatments with these combination therapies. Our study demonstrated that combining curcumin or chitosan with PDT at their subinhibitory concentrations represents a promising alternative strategy as localized therapy for effectively managing A. baumannii-associated wound infection. © 2025 The Authors

关键词： Acinetobacter baumannii Alternative therapy Biofilm eradication Chitosan Curcumin Multidrug-resistant (MDR) Photodynamic therapy (PDT) Wound infection

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Convergence of Teichmüller deformations in the universal Teichmüller space

arXiv

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arXiv 2018年

作者： Miyachi, Hideki Šarić, Dragomir Division of Mathematical and Physical Sciences Graduate School of Natural Science & Technology Kanazawa University Kakuma-machi Kanazawa Ishikawa920-1192 Japan Department of Mathematics Queens College of CUNY 65-30 Kissena Blvd FlushingNY11367 United States Mathematics PhD Program CUNY Graduate Center 365 Fifth Avenue New YorkNY10016-4309 United States

Let : D → C be an integrable holomorphic function on the unit disk D and D : D → T(D) the corresponding Teichmüller disk in the universal Teichmüller space T(D). For a positive t it is known that D(t) → [µ] ∈ PMLb(D) as t → 1, where µ is a bounded measured lamination representing a point on the Thurston boundary of T(D). We extend this result by showing that D: D → T(D) extends as a continuous map from the closed disk D to the Thurston bordification. In addition, we prove that the rate of convergence of D(λ) when λ → eiθ is independent of the type of the approach to eiθ ∈ ∂D.30F60, 32G15 Copyright © 2018, The Authors. All rights reserved.

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