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Integrating Chinese Herbal Medicine into Conventional Care Was Related to Lower Risk of Sarcopenia Among Rheumatid Arthritis Patients: A Retrospective, Population-Based Study

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Journal of Multidisciplinary Healthcare 2023年 16卷 3117-3127页

作者： Li, Hsin-Hua Livneh, Hanoch Huang, Hua-Lung Wang, Yu-Han Lu, Ming-Chi Chen, Wei-Jen Tsai, Tzung-Yi Department of Chinese Medicine Dalin Tzu Chi Hospital The Buddhist Tzu Chi Medical Foundation Chiayi 62247 Taiwan Rehabilitation Counseling Program Portland State University Portland 97207-0751 OR United States Department of Rehabilitation Dalin Tzu Chi Hospital The Buddhist Tzu Chi Medical Foundation Chiayi Taiwan Center of Sports Medicine Dalin Tzu Chi Hospital The Buddhist Tzu Chi Medical Foundation Chiayi 62247 Taiwan Division of Allergy Immunology and Rheumatology Dalin Tzu Chi Hospital The Buddhist Tzu Chi Medical Foundation Chiayi 62247 Taiwan School of Medicine Tzu Chi University Hualien 97004 Taiwan School of Post-Baccalaureate Chinese Medicine Tzu Chi University Hualien 97004 Taiwan Graduate Institute of Sports Science National Taiwan Sport University Taoyuan 33301 Taiwan Department of Medical Research Dalin Tzu Chi Hospital The Buddhist Tzu Chi Medical Foundation Chiayi 62247 Taiwan Department of Nursing Tzu Chi University of Science and Technology Hualien 97004 Taiwan Department of Environmental and Occupational Health College of Medicine National Cheng Kung University Tainan 70428 Taiwan

Objective: Sarcopenia is a frequently observed comorbidity of rheumatoid arthritis (RA) due to the chronic activation of the innate immune system. Accumulating evidence has indicated that Chinese herbal medicine (CHM) safely suppresses proinflammatory pathways and controls inflammation-associated disease, but its effect in reducing the risk of developing sarcopenia among RA subjects has not been established. We conducted a population-level cohort study to compare the sarcopenia risk in patients with RA who use or do not use CHM. Methods: Using claims from a nationwide insurance database, we recruited patients with newly diagnosed RA and without sarcopenia between 2002 and 2010. Propensity score matching was applied to randomly select sets of CHM users and non-CHM users to compare the sarcopenia risk until the end of 2013. The risk of new-onset sarcopenia was assessed using the Cox proportional hazards model. Results: As compared to non-CHM users, those receiving CHM treatment had a lower incidence of sarcopenia (7.69 vs 9.83 per 1000 person-years). CHM was correlated with a decreased chance of sarcopenia after controlling for potential covariates. Notably, use of CHM for more than two years may diminish the risk of getting sarcopenia by about 47% when taken as prescribed. Prescriptions of several herbal formulae may benefit the reduction of sarcopenia risk, such as Yan-Hu-Suo, Bei-Mu, Da-Huang, Huang Qin, Ping-Wei-San (PWS), Shu-Jing-Huo-Xue-Tang (SJHXT) and Chuan-Xiong-Cha-Tiao-San (CXCTS). Conclusion: This study produced new evidence as it is the first to show that the longer duration of CHM use was correlated to reduced risk of sarcopenia in a dose-dependent manner, implying that CHM treatment could be embraced as a routine care strategy for preventing sarcopenia. © 2023 Li et al.

关键词： Chinese herbal medicine cohort study rheumatoid arthritis sarcopenia

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Mapping of rain water harvesting potential at Keduang Sub-watershed, Central Java, Indonesia

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IOP Conference Series: Earth and environmental Science 2021年第1期824卷

作者： H R Dwiatmojo Komariah A H Ramelan E Priyanto Master Program of Environmental Science Post Graduate School Sebelas Maret University Soil Science Dept. Faculty of Agriculture Sebelas Maret University Environmental Science Post Graduate School Sebelas Maret University Watershed Management Technology Centre Ministry of Environmental and Forestry

One of the main issues in agriculture in this climate change era is the water crisis. It caused a drought that affected the delay of rice cultivation. A study found that Wonogiri Regency has very critical with a value of 163.1%. Hence, it is necessary to have an alternative solution to overcome it. In this case, utilizing rain by harvesting rainwater (RWH) can be used as an alternative to meet water needs during the dry season and for various other uses. One of the RWH applications is a small-farm reservoir (SFR). To identify the potential locations for RWH is using location suitability modelling based on GIS. The determination of the location depends on biophysical criteria such as rainfall, slope, soil texture, stream order, and land use. The socio-economic attributes consist of the distance to the river, road, settlement, and agriculture. To obtain the suitability location, after all of the maps are generated, next is reclassify the value to 0 and 1. In the end, the maps calculate with a raster calculator to define the suitability location that has value 1. Location and dimension details can find out. This study aims to determine the potential of RWH for agriculture (in specific, SFR) at Keduang Sub-watershed as a consideration for stakeholders' decision. The results showed 226 areas are potential for SFR implementation and will make it easier for stakeholders to decide by comparing the suitability location map and the long-term strategic map.

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Physical characteristics of modified cassava flour wastewater at room temperature

Physical characteristics of modified cassava flour wastewate...

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International Conference on Food Science and technology 2018, ICFST 2018

作者： Yaqin, N. Al-Baarri, A.N. Legowo, A.M. Widayat Budihardjo, M.A. Program of Environmental Science School of Post-Graduate Studies Diponegoro University Semarang Indonesia Food Technology Department Faculty of Animal and Agricultural Sciences Diponegoro University Semarang Indonesia Chemical Engineering Department Faculty of Engineering Diponegoro University Semarang Indonesia Center of Research and Services Diponegoro University Semarang Indonesia Department of Environmental Engineering Faculty of Engineering Diponegoro University Indonesia

Cassava is an agricultural material that is considered as important raw resources in the industrial sector. The benefits are even greater after being modified using lactic acid bacteria. However, the mocaf industry often causes water and air pollution. environmental problems arise after the fermentation process. Determination problems with lightness, TDS (Total Dissolved Solid), conductivity and pH analysis are required to measure the impact to the environment. This research was used waste water from mocaf during 3 days fermentation. The wastewater had the highest color level (Lightness) on initial day of fermentation at 83.7±3.73 and then decrease along the day of fermentation at the averages of 65.2±2.0. The highest TDS was resulted from the mocaf wastewater at a value of 1218 ± 4.6 ppm which continued to decline until day 4. The conductivity and pH showed a decrease along the day of fermentation. As conclusion, physical characteristic of wastewater from mocaf production could be analyzed specifically and determined through color, TDS, conductivity, and pH. © 2019 Published under licence by IOP Publishing Ltd.

关键词： Fermentation

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AHR is a Zika virus host factor and a candidate target for antiviral therapy (vol 52, pg 941, 2020)

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NATURE NEUROSCIENCE 2020年第10期23卷 1307-1307页

作者： Giovannoni, Federico Bosch, Irene Polonio, Carolina Manganeli Torti, Maria F. Wheeler, Michael A. Li, Zhaorong Romorini, Leonardo Rodriguez Varela, Maria S. Rothhammer, Veit Barroso, Andreia Tjon, Emily C. Sanmarco, Liliana M. Takenaka, Maisa C. Modaresi, Seyed Mohamad Sadegh Gutierrez-Vazquez, Cristina Zanluqui, Nagela Ghabdan dos Santos, Nilton Barreto Munhoz, Carolina Demarchi Wang, Zhongyan Damonte, Elsa B. Sherr, David Gehrke, Lee Peron, Jean Pierre Schatzmann Garcia, Cybele C. Quintana, Francisco J. Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital Harvard Medical School Boston MA USA Laboratorio de Estrategias Antivirales Departamento de Química Biológica Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires. CONICET—Instituto de Química Biológica Buenos Aires Argentina Institute for Medical Engineering and Science Massachusetts Institute of Technology Cambridge MA USA Department of Medicine Mount Sinai School of Medicine New York NY USA Neuroimmune Interactions Laboratory Immunology Department—ICB IV University of São Paulo São Paulo Brazil Scientific Platform Pasteur—USP University of São Paulo São Paulo Brazil Laboratorio de Investigación aplicada a Neurociencias Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia Buenos Aires Argentina Immunopathology and Allergy Post Graduate Program School of Medicine University of São Paulo São Paulo Brazil Department of Pharmacology Institute of Biomedical Science University of São Paulo São Paulo Brazil Dept. of Environmental Health Boston University School of Public Health Boston MA USA Program in Virology Division of Medical Sciences Harvard Medical School Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA

Zika virus (ZIKV) is a flavivirus linked to multiple birth defects including microcephaly, known as congenital ZIKV syndrome. The identification of host factors involved in ZIKV replication may guide efficacious therapeutic interventions. In genome-wide transcriptional studies, we found that ZIKV infection triggers aryl hydrocarbon receptor (AHR) activation. Specifically, ZIKV infection induces kynurenine (Kyn) production, which activates AHR, limiting the production of type I interferons (IFN-I) involved in antiviral immunity. Moreover, ZIKV-triggered AHR activation suppresses intrinsic immunity driven by the promyelocytic leukemia (PML) protein, which limits ZIKV replication. AHR inhibition suppressed the replication of multiple ZIKV strains in vitro and also suppressed replication of the related flavivirus dengue. Finally, AHR inhibition with a nanoparticle-delivered AHR antagonist or an inhibitor developed for human use limited ZIKV replication and ameliorated newborn microcephaly in a murine model. In summary, we identified AHR as a host factor for ZIKV replication and PML protein as a driver of anti-ZIKV intrinsic immunity.

关键词： Immunology Microbiology

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Attitude and knowledge towards the effectiveness of nucleic acid-based vaccines among healthcare workers and medical students in the Jordanian population

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Cogent Public Health 2022年第1期9卷 Article: 2145756页

作者： M. Emad Al Madadha Rama Rayyan Khalid E. Ahmed Nancy Al-Sanouri Saddam Al Demour Muayyad Ahmad 1 Department of Pathology Microbiology and Forensic Medicine School of Medicine the University of Jordan Amman Jordan2 University of Maryland Baltimore Institute of Marine and Environmental Technology Department of Microbiology and Immunology University of Maryland School of Medicine Baltimore Maryland USA 3 Medical Student Jordan University Faculty of Medicine Amman Jordan 4 Department of Medical Laboratory Sciences Post Graduate Program in Laboratory Sciences the University of JordanAmman Jordan 5 Department of Special Surgery School of Medicine The University of Jordan Amman Jordan 6 Clinical Nursing Department School of Nursing The University of Jordan Amman Jordan

Since the beginning of the COVID-19 pandemic, catastrophic mortality and morbidity rates and unknown long-term ramifications were caused, leading to focused efforts on implementing effective vaccination. Nucleic acid-based vaccines (NBVs), an emergent advance in vaccine development, presented high efficacy rates but controversy regarding this approach soon spread. This study assesses healthcare workers (HCWs) knowledge and attitude towards NBVs’ effectiveness. This cross-sectional study was conducted in Jordan from November 2020 to January 2021 through a web-based questionnaire. 320 participants were split into educated and uneducated groups, with the former being exposed to educational material on NBVs before survey completion. The educated group expressed increased concern towards NBVs’ side effects. Specifically, the risk of developing cancer due to genetic modification(40.8%), fever(69.4%), skin rash(58.0%), and amyloid deposition(40.8%) showed a significant difference. The educated group preferred RNA-based NBVs over DNA-based ones(43.9%), had double the response rate, provided more scientifically accurate answers, and showed a more positive attitude towards the ability of NBVs to induce cellular immunity (57.3%) and prevent chronic forms of COVID-19(57.3%) (p < 0.05). Because HCWs are the most integral players in shaping public opinion about NBVs, thorough educational material on NBVs needs to be integrated within the curricula of health-related programs to bridge the gap present. This could prove vital in ensuring the success of the current and future vaccination campaigns.

关键词： COVID-19 nucleic acid vaccine healthcare workers vaccination effectiveness

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An approach on monitoring evolution of projects by professional performance assessment: A case study at the amazon regional center of the National Institute for Space Research

An approach on monitoring evolution of projects by professio...

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2018 Portland International Conference on Management of Engineering and technology, PICMET 2018

作者： Da Silva, Marck Barros, Marcia Nazare Rodrigues Santos, Lucyana Barros Adami, Marcos Gomes, Alessandra Rodrigues Foundation for Science Technology and Space Applications FUNCATE Saõ José dos Campos Brazil National Institute for Space Research INPE Amazon Regional Center Belém Brazil Federal University of Para Postgraduate Program in Amazon's Natural Resource Management and Local Development UFPA PPGEDAM Belém Brazil Federal University of Para Post-Graduate Program in Environmental Sciences UFPA PPGCA Belém Brazil

ISBN: (纸本)9781890843373

This work investigates strategic management processes of projects involved in the Brazilian aerospace field, addressing the Regional Center of the Amazon of the National Institute of Space Research. It proposes an approach in the monitoring of the evolution of projects by evaluation of professional performance, showing results in graphs and the need to survey and follow the most evident and significant technological advances in the mapping environment of land use and land cover in the Amazon. It addresses the main difficulties faced in the process of managing projects and people to achieve goals, needing to know the Geographic Information System tools used by employees, such as Terramazon, and their respective times consumed in this type of software. The work intends to serve as a basis for investigating, developing and implementing new management options that will reduce the efforts required by managers and administrators during the process of monitoring the evolution of projects. The methodology of Project Management Institute (PMI) and its Guide to the Project Management Body of Knowledge (PMBOK Guide) was used in this research work, ensuring an international quality. © 2018 Portland International Conference on Management of Engineering and technology, Inc. (PICMET).

关键词： Project management

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An Approach on Monitoring Evolution of Projects by Professional Performance Assessment: A Case Study at the Amazon Regional Center of the National Institute for Space Research

An Approach on Monitoring Evolution of Projects by Professio...

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Portland International Conference on Management of Engineering and technology (PICMET)

作者： Marck da Silva Márcia Nazaré Rodrigues Barros Lucyana Barros Santos Marcos Adami Alessandra Rodrigues Gomes Foundation for Science Technology and Space Applications São José dos Campos Brasil Post-Graduate Program in Environmental Sciences Federal University of Para Belém Brasil Postgraduate Program in Amazon's Natural Resource Management and Local Development Federal University of Para Belém Brasil INPE Amazon Regional Center Belém Brasil

关键词： Monitoring Project management Forestry Satellites Law Software

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Physical Characteristics of Modified Cassava Flour Wastewater at Room Temperature

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IOP Conference Series: Earth and environmental Science 2019年第1期292卷

作者： N Yaqin A N Al-Baarri A M Legowo Widayat M A Budihardjo Program of Environmental Science School of Post Graduate Studies Diponegoro University Semarang Indonesia Center of Research and Services-Diponegoro University Semarang Indonesia Food Technology Department Faculty of Animal and Agricultural Sciences Diponegoro University Semarang Indonesia Chemical Engineering Department Faculty of Engineering Diponegoro University Semarang Indonesia Department of Environmental Engineering Faculty of Engineering Diponegoro University Indonesia

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The Biodiversity of Flora and Fauna in the Re-vegetation Area in The post-Mining Area of Pongkor

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IOP Conference Series: Earth and environmental Science 2020年第1期501卷

作者： A Kusumoarto A Gunawan Machfud A Hikmat Doctoral Student Program Natural Resource and Environmental Management Science School of Post-Graduate IPB University Jl. Raya Pajajaran Bogor Indonesia 16143 Lecturer in Architecture Study Program Faculty of Technic and Computer Science Indraprasta PGRI University Jl. Raya Nangka No. 58C RT.5/RW.5 Tanjung Barat Kecamatan Jagakarsa Kota Jakarta Selatan Daerah Khusus Ibukota Jakarta 12530 Lecturer in Landscape Architecture Department IPB University Jl. Raya Darmaga Bogor Indonesia 16680 Lecturer in AgroIndustrial Technology Department IPB University Jl.Raya Darmaga Bogor Indonesia 16680 Lecturer in Conservation of Forest and Ecotourism Department IPB University Jl. Raya Darmaga Bogor Indonesia 16680

The Pongkor post-mining area is designated as one of the ecotourism areas in Bogor. This area has biodiversity of flora and fauna. This study aims to: (1) analysis the importance value index (IVI) of flora types; (2) analysis species richness index, species diversity index, and relative species abundance index; (3) analysis the beauty, the uniqueness and the rarity of the flora and fauna types. The method used in this research is quantitative descriptive. Based on the identification results, 185 species of flora are distributed in this region. During the rainy season, 15 species of herpetofauna were identified, 32 types of aves, and 4 types of mammals, while in the dry season 19 species of herpetofauna were identified, 23 types of aves, and 2 types of mammals. Based on the results of the analysis conducted on these flora and fauna, there are flora species that have high IVI values and some beautiful and unique flora species that are in the category of endangered species. Besides that, there are also fauna species which have a value of species richness index, species diversity index, and relative species abundance index, as well as some beautiful, unique, and fauna species that are in the category of endangered species.

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Self-Compassion Around the World: Measurement Invariance of the Short Form of the Self-Compassion Scale (SCS-SF) Across 65 Nations, 40 Languages, Gender Identities, and Age Groups

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Mindfulness 2025年 1-28页

作者： Swami, Viren Tran, Ulrich S. Voracek, Martin Aavik, Toivo Ranjbar, Hamed Abdollahpour Adebayo, Sulaiman Olanrewaju Afhami, Reza Ahmed, Oli Aimé, Annie Akel, Marwan Al Halbusi, Hussam Alexias, George Ali, Khawla F. Alp-Dal, Nursel Alsalhani, Anas B. Álvarez-Solas, Sara Amaral, Ana Carolina Soares Andrianto, Sonny Aspden, Trefor Argyrides, Marios Aruta, John Jamir Benzon R. Atkin, Stephen Ayandele, Olusola Baceviciene, Migle Bahbouh, Radvan Ballesio, Andrea Barron, David Bellard, Ashleigh Bender, Sóley Sesselja Beydaǧ, Kerime Derya Birovljević, Gorana Blackburn, Marie-Ève Borja-Alvarez, Teresita Borowiec, Joanna Bozogáňová, Miroslava Bratland-Sanda, Solfrid Browning, Matthew H. E. M. Brytek-Matera, Anna Burakova, Marina Çakır-Koçak, Yeliz Camacho, Pablo Camilleri, Vittorio Emanuele Cazzato, Valentina Cerea, Silvia Chaiwutikornwanich, Apitchaya Chaleeraktrakoon, Trawin Chambers, Tim Chen, Qing-Wei Chen, Xin Chien, Chin-Lung Chobthamkit, Phatthanakit Choompunuch, Bovornpot Compte, Emilio J. Corrigan, Jennifer Cosmas, Getrude Cowden, Richard G. Czepczor-Bernat, Kamila Czub, Marcin da Silva, Wanderson Roberto Dadfar, Mahboubeh Dalley, Simon E. Dany, Lionel Datu, Jesus Alfonso D. de Carvalho, Pedro Henrique Berbert de Holanda Coelho, Gabriel Lins De Jesus, Avila Odia S. Debbabi, Sonia Harzallah Dhakal, Sandesh Di Bernardo, Francesca Dimitrova, Donka D. Dion, Jacinthe Dixson, Barnaby Donofrio, Stacey M. Drysch, Marius Du, Hongfei Dzhambov, Angel M. El-Jor, Claire Enea, Violeta Eskin, Mehmet Farbod, Farinaz Farrugia, Lorleen Fian, Leonie Fisher, Maryanne L. Folwarczny, Michał Frederick, David A. Fuller-Tyszkiewicz, Matthew Furnham, Adrian García, Antonio Alías Geller, Shulamit Ghisi, Marta Ghorbani, Alireza Martinez, Maria Angeles Gomez Gradidge, Sarah Graf, Sylvie Grano, Caterina Gyene, Gyöngyvér Hallit, Souheil Hamdan, Motasem Handelzalts, Jonathan E. Hanel, Paul H. P. Hawks, Steven R. Hekmati, Issa Helmy, Mai Hill, Tetiana Hina, Farah Holenweger, Geraldine Hřebíčková, Martina Ijabadeniyi, Olasupo Augustine Imam, Asma İ School of Psychology and Sport Science Anglia Ruskin University Cambridge United Kingdom Centre for Psychological Medicine Perdana University Kuala Lumpur Malaysia Department of Cognition Emotion and Methods in Psychology Faculty of Psychology University of Vienna Vienna Austria Institute of Psychology University of Tartu Tartu Estonia Department of Psychology Istinye University Istanbul Turkey Department of Psychology and Behavioural Studies Ekiti State University Ado-Ekiti Nigeria Department of Art Studies Tarbiat Modares University Tehran Iran Department of Psychology University of Chittagong Chattogram Bangladesh Department of Psychoeducation and Psychology Université du Québec en Outaouais Saint-Jérôme Canada INSPECT-LB: National Institute of Public Health Clinical Epidemiology and Toxicology Beirut Lebanon School of Pharmacy Lebanese International University Beirut Lebanon Department of Management Ahmed Bin Mohammad Military College Doha Qatar Faculty of Psychology Panteion University of Social and Political Sciences Athens Greece Royal College of Surgeons Ireland-Bahrain Adliya Bahrain Department of Midwifery Faculty of Health Sciences Munzur University Tunceli Turkey Department of Oral Medicine and Diagnostic Sciences Vision College of Dentistry and Nursing Vision Colleges Riyadh Saudi Arabia Facultad de Salud Universidad Internacional de La Rioja Logroño Spain Science and Technology of Southeast Minas Gerais Federal Institute of Education Barbacena Brazil Department of Psychology Universitas Islam Indonesia Yogyakarta Indonesia Department of Psychology Aberystwyth University Ceredigion United Kingdom Department of Psychology Neapolis University Pafos Paphos Cyprus Department of Psychology De La Salle University Manila Philippines Department of General Studies The Polytechnic Ibadan Nigeria Department of Psychology University of Ibadan Ibadan Nigeria Health Research and Innovation Science Centre Faculty of Health Sciences Klai

Objectives: The 12-item Self-Compassion Scale–Short Form (SCS–SF) is a widely used instrument for the assessment of self-compassion. To date, there have been few examinations of this instrument’s psychometric properties, particularly across nations and languages. Therefore, we used data from the Body Image in Nature Survey (BINS) to assess measurement invariance of the SCS–SF across nations, languages, gender identities, and age groups. Methods: Participants (N = 56,968) from 65 nations completed the SCS–SF in 40 languages. Using these data, we tested various hypothesised models of the SCS–SF in the total sample and, using multi-group confirmatory factor analysis, tested for invariance of the optimal model across national groups, languages, gender identities, and age groups. Results: In the total dataset, we found that an 11-item, 2-factor model (i.e., SCS-11) provided best fit to the data, with the two factors tapping distinct constructs of compassionate and uncompassionate self-responding. The SCS-11 was found to be partially scalar invariant across national groups and languages, and fully scalar invariant across gender identities and age groups. There was wide variation in latent means for the two factors, particularly across national groups and languages. Further analyses showed negligible associations between the two factors and sociodemographic variables, including marital status, financial security, and urbanicity. Conclusions: Our results suggest that it may be possible to derive a stable 2-factor model of the SCS–SF for use in cross-cultural research, but also highlight the likelihood of cross-national and cross-linguistic variations in the way that self-compassion is understood. © The Author(s) 2025.

关键词： Cross-cultural Measurement invariance Multi-group confirmatory factor analysis (MG-CFA) Self-Compassion Scale Short Form

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