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1st International Conference on Life science and technology, ICoLiST 2018

作者： Maryanto, Sugeng Marsono, Yustinus Department of Nutrition Faculty of Health Science Universitas Ngudi Waluyo Jl. Diponegoro 186 Semarang Indonesia Department of Food Science Post-Graduate Program Gadjah Mada University Jl. Flora No. 1 Bulaksumur Yogyakarta Indonesia

Red guava is a fruit species with high vitamin C content and the highest fibers, in particular, soluble fiber (pectin) among tropical fruits and cereals. The soluble fiber is hypocholesterolemic in the body. Therefore, it has the potential to reduce cholesterol content. This study aimed to assess the potential of red guava in reducing cholesterol content in hypocholesterolemic rats. This study applied a pure experiment using a randomized pretestposttest group design on hypocholesterolemic Sprague Dawley rats. The rats were fed with 0.72 g of red guava and pectin supplement as a comparison. The total cholesterol content, LDL, HDL and triglyceride were measured by CHOD-PAP and GPO-PAP methods. Data analysis used t-test and ANOVA with significance rate of 0.05. Red guava intake to the hypocholesterolemic rats significantly reduced the contents of: total cholesterol to 57.8 mg/dL (32%), LDL to 25.5 mg/dL (43%), triglyceride to 19.7 mg/dL (18%). Conversely, it significantly increased HDL content to 10.6 mg/dL (18%). The red guava has proven to give hypocholesterolemic effect by reducing the total cholesterol LDL and triglyceride;Conversely, it significantly increased HDL. © 2019 IOP Publishing Ltd. All rights reserved.

关键词： Fatty acids

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Preliminary study: Production and quality of signal grass (Brachiaria decumbens) on the post mining land

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AIP Conference Proceedings 2023年第1期2628卷

作者： N. A. A. Toputri R. A. Habibi E. Harri Sema R. F. Utamy S. Hasan Animal Husbandry and Technology Post-Graduate Program Hasanuddin University Makassar Indonesia Nursery PT. Vale Sorowako East Luwu South Sulawesi Indonesia Animal Nutrition and Feed Technology Faculty of Agriculture Puangrimaggalatung University Sengkang Indonesia Faculty of Animal Science Universitas Hasanuddin Makassar South Sulawesi Indonesia

The post-mining land decrease soil fertility. Soil fertility is required for plant growth. One way to minimize this soil fertility is by planting grass and legume in a mixed-cropping system. This preliminary study was aimed to evaluate the production and quality of signal grass and legume on the post-mining land of PT Vale Indonesia, Tbk. This study used a descriptive/survey method such as direct measurements and observations in the field. The results showed the average production of fresh weight (7.5 tons/Ha), dry matter (1.5 tons/Ha), chlorophyll (30 mg/g leaves), and leaf area (22.5 cm) of signal grass without legumes. Meanwhile, the average production of fresh weight (15.80 tons/Ha), dry matter (3.16 tons/Ha), chlorophyll (38 mg/g leaves), and leaf area (35.6 cm) of signal grass with legumes.

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The Atherogenic Index of Plasma Treated with Red Guava (Psidium guajava L.) 1

The Atherogenic Index of Plasma Treated with Red Guava (Psid...

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1st International Conference on Life science and technology, ICoLiST 2018

作者： Maryanto, Sugeng Marsono, Y. Department of Nutrition Faculty of Health Science Universitas Ngudi Waluyo Jl. Diponegoro 186 Semarang Indonesia Department of Food Science Post-Graduate Program Gadjah Mada University Jl. Flora No. 1 Bulaksumur Yogyakarta Indonesia

Red guava contains fiber especially high soluble fiber (pectin). Soluble fiber in the body is hypocholesterolemia. This research aimed to know the effect of administering red guava on AIP (Atherogenic Index of Plasma) in hypocholesterolemia rats. This research was a pure experiment using the design of randomized pretest-posttest control group design to Sprague Dawley rats made into hypocholesterolemia. The rats were divided into four groups: group 1 given standard food, group 2, 3, and 4 given high cholesterol food. Group 3 and 4 were added with red guava powder as many as 0.72 g and pectin equal to the one in red guava powder. Lipid profile was checked by using Enzymatic Colorimetric Test CHOP-PAP and GPO-PAP including the rate of total cholesterol, LDL, HDL, and triglycerides. AIP was counted based on log (TG/HDL). The data analysis used t-test and ANOVA with a 0.05 significance level. The administration of red guava in hypocholesterolemia rats was significantly proven to be able to lower lipid profile by lowering total cholesterol (32%), LDL (43%), triglycerides (18%),and by increasing HDL (18%). These results were similar to the decrease by administering pectin as many as 32%, 47%, and 20% respectively. The results of counting AIP showed that the administration of red guava and pectin could lower AIP score significantly as many as 0.16 and 0.17 respectively which increased in the groups getting high cholesterol food. The administration of red guava in hypocholesterolemia rats was proven to be able to lower AIP. © 2019 IOP Publishing Ltd. All rights reserved.

关键词： Rats

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Protective effect and antioxidative efficacy of Moringa stenopetala leaf extract in BV-2 microglial cell

Food Chemistry Advances

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food Chemistry Advances 2024年 5卷

作者： Adefegha, Stephen Adeniyi Mostardeiro, Vitor Morsch, Vera Maria Morel, Ademir F. Da Cruz, Ivana Beatrice Manica Somacal, Sabrina Oboh, Ganiyu Schetinger, Maria Rosa Chitolina Functional Foods Nutraceuticals and Phytomedicine Laboratory Department of Biochemistry Federal University of Technology P. M. B. 704 Akure Nigeria Graduate Program in Toxicological Biochemistry Department of Biochemistry and Molecular Biology Center of Natural and Exacts Sciences Federal University of Santa Maria RS Santa Maria 97105-900 Brazil Department of Chemistry Center of Natural and Exacts Sciences Federal University of Santa Maria RS 97105-900 Brazil Biogenomics Laboratory Department of Morphology Federal University of Santa Maria RS 97105-900 Brazil Department of Food Science and Technology Center for Rural Sciences Federal University of Santa Maria RS 97105-900 Brazil

Moringa stenopetala is often consumed as food and used in folkloric medicine for the management of several diseases including neurodegenerative diseases. This study investigated the protective effect and antioxidant efficacy of aqueous extract of Moringa stenopetala in BV-2 microglial cells. Aqueous extracts of M. stenopetala were prepared, lyophilized and reconstituted in 0.5% dimethylsulphoxide (DMSO). Cells were treated with M. stenopetala extracts (0.1–100 µg/ml) for cell viability assay and nitric oxide (NO) production tests. However, M. stenopetala extract (50 µg/ml) was used in the treatment of cells for the determination of protein carbonyl content and reactive oxygen species (ROS) level. Incubation of BV-2 microglia cell with M. stenopetala extract maintained cell viability, diminished NO and ROS levels, and reduced protein carbonyl contents. Chlorogenic acid, rutin, kaempferol and quercetin derivatives were the main phenolic compounds identified in M. stenopetala leaf extract. In conclusion, this study suggests that M. stenopetala extract is rich in antioxidant and contains bioactive neuroprotective agents. © 2024 The Author(s)

关键词： Antioxidant BV-2 microglial cell Cell viability Moringa stenopetala Oxidative stress

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Retraction notice to "Organic composts as A vehicle for the entry of microplastics into the environment: A comprehensive review" [Sci. Total Environ. 892 (2023) 164758]

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The science of the total environment 2024年 957卷 177731页

作者： Van-Re Le Minh-Ky Nguyen Hoang-Lam Nguyen Chitsan Lin Md Refat Jahan Rakib Van-Anh Thai Van-Giang Le Guilherme Malafaia Abubakr M Idris Ho Chi Minh City University of Food Industry (HUFI) 140 Le Trong Tan Street Tan Phu District Ho Chi Minh City 700000 Viet Nam. Faculty of Environment and Natural Resources Nong Lam University of Ho Chi Minh City Hamlet 6 Linh Trung Ward Thu Duc City Ho Chi Minh City 700000 Viet Nam Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. Department of Civil Engineering McGill University Montreal Canada. Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan Department of Marine Environmental Engineering National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. Department of Fisheries and Marine Science Faculty of Science Noakhali Science and Technology University Noakhali 3814 Bangladesh. Institute of Aquatic Science and Technology National Kaohsiung University of Science and Technology Kaohsiung City 81157 Taiwan. Central Institute for Natural Resources and Environmental Studies Vietnam National University Hanoi 111000 Viet Nam. Post-Graduation Program in Ecology Conservation and Biodiversity Federal University of Uberlândia Uberlândia MG Brazil Post-Graduation Program in Biotechnology and Biodiversity Federal University of Goiás Goiânia GO Brazil Post-Graduation Program in Conservation of Cerrado Natural Resources Goiano Federal Institute Urutaí GO Brazil. Department of Chemistry College of Science King Khalid University 61431 Abha Saudi Arabia Research Center for Advanced Materials Science (RCAMS) King Khalid University Abha 61421 Saudi Arabia.

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Information technology of Motor Vehicle Databases Use to Prevent Terrorist Emergencies

Information Technology of Motor Vehicle Databases Use to Pre...

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International Conference on Advanced Computer Information Technologies (ACIT)

作者： Yuliia Honcharenko Natalia Kasatkina Yurii Maslyiak Bogdan Maslyiak Lyudmyla Honchar Department of Information Technologies European University Kyiv Ukraine Division of Doctoral and Post-Graduate National University of Food Technology Kyiv Ukraine Department of Computer Science Ternopil National Economic University Ternopil Ukraine

ISBN: (数字)9781728167602

ISBN: (纸本)9781728167619

Based on the analysis of gradation scheme of motor vehicles situational background near a protected object of a critical infrastructure, the process of data collecting and filling the database and knowledgebase of the protected object main server as well as the procedure of violators' identification and collecting data on them is considered in the paper. After that, the structure of the control algorithm is described. The algorithm defines the application of information technology for the use of motor vehicles databases to prevent the terrorist emergencies.

关键词： Databases Terrorism Critical infrastructure Servers Standards Information technology Vehicle dynamics

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Role of plant genetic resources in encountering climate change challenge 10

Role of plant genetic resources in encountering climate chan...

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10th Annual International Conference 2020 on Environmental and Life sciences, AIC-ELS 2020

作者： Ichsan, C.N. Darusman Sulaiman, M.I. Andini, R. Doctoral Program in Agricultural Sciences Post Graduate School Universitas Syiah Kuala Jl. Tgk. Chik Pante Kulu No.3 Banda Aceh Indonesia Department of Soil Science Universitas Syiah Kuala Jl. Tgk. Hasan Krueng Kalee No. 3 Banda Aceh Indonesia Department of Agricultural Product Technology Universitas Syiah Kuala Jl. Tgk. Hasan Krueng Kalee No. 3 Banda Aceh Indonesia Department of Forestry Universitas Syiah Kuala Jl. Tgk. Hasan Krueng Kalee No. 3 Banda Aceh Indonesia

The world is encountering a global threat: Climate change. It is estimated that the average air temperature will raise 3.7-7.8 °C by 2100. The possible impacts will vary, however, agriculture will be adversely affected marked with yield loss of staple crops such as rice and maize and altered post-harvest quality of horticulture products. On the other hand, the world food and Agriculture Organization (UN-FAO) has set a target 'zero hunger' by 2030', despite the five big challenges ahead: I) protracted conflict, ii) growing inequality, iii) rapid urbanization, iv) economic challenges, v) drought and natural disasters. The existing plant genetic resources, particularly the wild, neglected, and underutilized species has a great role and bears big potential to be exploited and targetted to achieve food and nutrition security, esp. in the densely populated regions with malnutrition problem e.g. in Asia and sub-Saharan regions. However, a key to future and sustainable crop production lies in the collection of crop and their wild relatives stored in ex-situ, or in-situ. This paper aims to explain the importance of plant genetic resources as well as the potential of some underutilized crops closely attributed with drought resistence, such as sorghum (Sorghum bicolor L. Moench), amaranth (Amaranthus sp.). These crops bear potential to support national food security program. © Published under licence by IOP Publishing Ltd.

关键词： Crops

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Phage display-derived alpaca nanobodies as potential therapeutics for Naja atra snake envenomation

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Applied and Environmental Microbiology 2024年第8期90卷 e0012124页

作者： Wang, Wei-Chu Chang, Jungshan Lee, Chi-Hsin Chiang, Yu-Wei Leu, Sy-Jye Mao, Yan-Chiao Chiang, Jen-Ron Yang, Chun-Kai Wu, Chao-Jung Yang, Yi-Yuan Ph.D. Program in Medical Biotechnology College of Medical Science and Technology Taipei Medical University Taipei Taiwan Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei Taiwan International Master/Ph.D. Program in Medicine College of Medicine Taipei Medical University Taipei Taiwan International Ph.D. Program for Cell Therapy and Regeneration Medicine College of Medicine Taipei Medical University Taipei Taiwan School of Medical Laboratory Science and Biotechnology College of Medical Science and Technology Taipei Medical University Taipei Taiwan Core Laboratory of Antibody Generation and Research Taipei Medical University Taipei Taiwan Department of Medical Research Taipei Veterans General Hospital Taipei Taiwan Department of Biology and Anatomy National Defense Medical Center Taipei Taiwan Foundation for Poison Control Taipei Taiwan Department of Microbiology and Immunology School of Medicine College of Medicine Taipei Medical University Taipei Taiwan School of Medicine National Defense Medical Centre Taipei Taiwan Department of Post-Baccalaureate Medicine College of Medicine National Chung Hsing University Taichung Taiwan Division of Clinical Toxicology Department of Emergency Medicine Taichung Veterans General Hospital Taichung Taiwan Bioproduction Plants National Institute of Infectious Diseases and Vaccinology National Health Research Institutes Miaoli Taiwan Interdisciplinary Research on Ecology and Sustainability National Dong Hwa University Hualien Taiwan

Naja atra, the Chinese cobra, is a major cause of snake envenomation in Asia, causing hundreds of thousands of clinical incidents annually. The current treatment, horse serum-derived antivenom, has unpredictable side effects and presents manufacturing challenges. This study focused on developing new-generation snake venom antidotes by using microbial phage display technology to derive nanobodies from an alpaca immunized with attenuated N. atra venom. Following confirmation of the immune response in the alpaca, we amplified VHH genes from isolated peripheral blood mononuclear cells and constructed a phage display VHH library of 1.0 × 107 transformants. After four rounds of biopanning, the enriched phages exhibited increased binding activity to N. atra venom. Four nanobody clones with high binding affinities were selected: aNAH1, aNAH6, aNAH7, and aNAH9. Specificity testing against venom from various snake species, including two Southeast Asian cobra species, revealed nanobodies specific to the genus Naja. An in vivo mouse venom neutralization assay demonstrated that all nanobodies prolonged mouse survival and aNAH6 protected 66.6% of the mice from the lethal dosage. These findings highlight the potential of phage display-derived nanobodies as valuable antidotes for N. atra venom, laying the groundwork for future applications in snakebite treatment. Copyright © 2024 American Society for Microbiology. All Rights Reserved.

关键词： Mammals

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Gold Nanoparticle Decorated Bismuth Vanadate Casting on Screen-Printed Electrode for Chlortetracycline Detection in Tap Water

SSRN

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SSRN 2024年

作者： Ngo, Duy Ba Gopi, Praveen Kumar Rajkumar, Muniyandi Chen, Shen-Ming Rijiravannich, Patsamon Khownarumit, Porntip Somasundrum, Mithran Surareungchai, Werasak Bangkhuntien-chaitalay Rd. Bangkok10150 Thailand Analytical Sciences and National Doping Test Institute Mahidol University Rama VI Rd. Bangkok10400 Thailand Electroanalysis and Bioelectrochemistry Lab Department of Chemical Engineering and Biotechnology National Taipei University of Technology No.1 Section 3 Chung-Hsiao East Rd. Taipei106 Taiwan Bioscience and System Biology Research Team National Center for Genetic Engineering and Biotechnology National Sciences and Technology Development Agency at KMUTT Bangkhuntien-chaitalay Rd. Bangkok10150 Thailand Pilot Plant Development and Training Institute KMUTT Bangkhuntien-chaitalay Rd. Bangkok10150 Thailand Nanoscience and nanotechnology graduate program Faculty of Science KMUTT Pracha Uthit Rd. Bangkok10140 Thailand PSG College of Arts and Science Civil Aerodrome Post Tamil Nadu Coimbatore641014 India Quarter 6 Linh Trung Ward Thu Duc City Ho Chi Minh City720400 Viet Nam

Background Chlortetracycline (CTC) belongs to the class of tetracycline’s compounds, which is known for its antibacterial activity. CTC was largely consumed by farm animals than humans, which leads to the growth antibiotic – resistant bacteria and environmental contamination. So far no one reported the electrochemical detection and determination of CTC by using AuNPs@BiVO4 composite. Some reports have been reported using conventional chromatography which is most expensive, time-consuming and highly equipped method. Results Here, we report a simple method for preparing gold nanoparticle decorated bismuth vanadate (AuNPs@BiVO4), which was dropped cast on a screen-printed carbon electrode (SPCE). The AuNPs@BiVO4 and AuNPs@BiVO4/SPCE materials were characterized using TEM, SEM-EDX, XPS, DLS, ELS, EIS, and CV. The as-prepared AuNPs@BiVO4/SPCE was used to detect and determine chlortetracycline (CTC) by different pulse potentials in phosphate buffer pH 7.0. The electrode possessed a wide linear range of 0.99 – 19.06 µM, with obtained LOD = 0.15 µM, LOQ = 0.49 µM, and sensitivity = 0.059 μA μM-1 cm-2. It also exhibited good selectivity, stability, and repeatability, recovering 87.14% - 100% for detecting CTC in Mili Q and tap water. Significance Facile and rapid synthesis of AuNPs@BiVO4 nanocomposite film modified electrode at physiological pH conditions has been prepared and A highly electrochemical detection and determination of CTC using AuNPs@BiVO4 nanocomposite film has been developed for the first time. Thus, the proposed electrode could be applied for the detection and determination of CTC in water sources and has the potential to be used for real sample analysis. © 2024, The Authors. All rights reserved.

关键词： Nanocomposites

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Liposomal bupivacaine administration is not superior to traditional periarticular injection for postoperative pain management following total knee arthroplasty: a meta-analysis of randomized controlled trials

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Journal of Orthopaedic Surgery and Research 2023年第1期18卷 206-206页

作者： Chen, Jian-Jiun Wu, Yun-Che Wang, Jun-Sing Lee, Cheng-Hung Department of Orthopedics Taipei Veterans General Hospital Taipei Taiwan Department of Orthopedics Taichung Veterans General Hospital No.1650 Sec. 4 Boulevard Taichung 40705 Taiwan Division of Endocrinology and Metabolism Department of Internal Medicine Taichung Veterans General Hospital No.1650 Sec. 4 Boulevard Taichung 40705 Taiwan Ph.D. Program in Translational Medicine National Chung Hsing University Taichung Taiwan Department of Post-Baccalaureate Medicine College of Medicine National Chung Hsing University Taichung Taiwan Department of Food Science and Technology Hung Kuang University Taichung Taiwan

Background: Liposomal bupivacaine (LB) is a relatively new formulation that slowly releases bupivacaine to extend its efficacy for 72–96 h. It is inconclusive whether LB offers better efficacy than traditional periarticular injection (TPAI) following total knee arthroplasty (TKA). Methods: Relevant randomized controlled trials (RCTs) were searched using electronic databases, including PubMed, Cochrane Library, EMBASE, and Web of science. Review Manager 5.4.1 was used for calculations. Results: Sixteen RCTs were included in this meta-analysis. LB had better effects on morphine consumption equivalents during postoperative 24–48 h than TPAI. No significant difference was observed in pain relief, incidence of nausea and vomiting, or length of hospital stay between the two groups. Conclusion: LB administration during TKA is not superior to TPAI. Studies with larger sample size are needed to validate our findings. PROSPERO registration number: CRD42022355094. © 2023, The Author(s).

关键词： Liposomal bupivacaine Total knee arthroplasty Traditional periarticular injection

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