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Cleaner Chemical Engineering 2025年 11卷

作者： Jefferson Luiz Alves Marinho Francisco Assis Bezerra da Cunha Raimundo Nonato Pereira Teixeira Henrique Douglas Melo Coutinho Jorge Marcell Coelho Menezes Francisco José de Paula Filho Lucia Raquel de Lima Cícera Datiane de Morais Oliveira Tintino Hyan Thompson Oliveira Lopes Paulo Ives Pereira de Alcântara Post-Graduate Program in Biological Chemistry - PPQB at the Regional University of Cariri - URCA Crato Ceará Brazil Science and Technology Center at the Federal University of Cariri - UFCA Juazeiro do Norte Ceará Brazil Pharmacotoxicological Prospection of Bioactive Products Laboratory - UFPE Recife Pernambuco Brazil Analytical and Environmental Chemistry Laboratory - URCA Crato Ceará Brazil

The intensification of human activities, consumption, production, and exploitation of raw materials, coupled with rapid population growth and industrial activity development, has led to significant environmental impacts. As civilization progresses, the level of environmental pollution with toxic metals has also intensified. The ability to quickly detect heavy metal pollution in wastewater and find its source is critical for environmental monitoring and protection. In the search for cheaper and more economical materials to be used as precipitants, civil construction waste has been used for this application. In this context, the present study aimed to evaluate the utilization of construction and demolition waste (gypsum and cementitious mortar) in the retention of Copper, Lead, and Nickel metal ions. The assessment of the removal capacity of these metal ions using gypsum powder and cementitious mortar was conducted through chemical precipitation using batch experiments. The results obtained for Pb 2+ ions showed that increasing the mass of gypsum from 10 to 100 g resulted in precipitation rates ranging from 97.29 to 98.31 %. Gypsum also proved to be a viable alternative for Cu 2+ precipitation with rates of 92.99 to 96.65 %, while the most significant retention rate for Ni 2+ was observed for the mass of 100 g, reaching 94.63 %. In experiments using different types of cementitious mortar (ACI, ACII, ACIII, and common) as precipitants in a solution contaminated with copper at a constant concentration of 600 mg/L, it was found that the precipitation rates were practically the same, with ACIII mortar showing the highest percentage of precipitation. Therefore, the results obtained demonstrated that construction and demolition waste by-products rich in gypsum and cementitious mortar are efficient in removing toxic metals, representing promising alternatives for wastewater decontamination.

关键词： Toxic metals Chemical precipitation Construction and demolition waste Metal removal Geomaterials

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Cellucalst enzyme-assisted extraction of Sargassum horneri enhances the immunomodulation by regulating TLR4/MyD88/NF-kB pathway in murine splenocytes with or without Concanavalin A

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Biomedicine and Pharmacotherapy 2024年 181卷 117673-117673页

作者： Yang, Jiwon Kim, Hyo Jin Herath, Kalahe Hewage Iresha Nadeeka Madushani Jee, Youngheun Interdisciplinary Graduate Program in Advanced Convergence Technology & Science Jeju National University Jeju 63243 South Korea Department of Food Bioengineering Jeju National University Jeju 690-756 South Korea Department of Environmental Health Harvard T.H. Chan School of Public Health Harvard University Boston Massachusetts United States Department of Biosystems Engineering Faculty of Agriculture and Plantation Management Wayamba University Gonawila Makandura 60170 Sri Lanka Department of Veterinary Medicine and Veterinary Medical Research Institute Jeju National University Jeju 64243 South Korea

Sargassum horneri (S. horneri) is an edible species of large brown algae inhabiting along the coasts of northeastern Asia. The study focuses on the impact of celluclast enzyme extract of S. hoeneri (SHC) on various immune cell populations in splenocytes including granulocytes, macrophages, dendritic cells, and T lymphocytes. SHC alone increased the population of granulocytes and macrophages and the secretion of M1 macrophage-derived cytokines (TNF-α, IL-22), and M2 macrophage-derived cytokines (IL-4, IL-10). Interestingly, however, SHC suppressed the concanavalin A (Con A)-expanded populations of macrophages, dendritic cells, granulocytes, T and B cells, and Con A-promoted secretion of M1-macrophage derived cytokines (IFN-γ, IL-1β, TNF-α, IL-17, IL-22) and M2-macrophage derived cytokines (IL-4, IL-10, IL-13, TGF-β). SHC further restrained the Th1, Th2, and Th17 cell responses through attenuating the expression of respective transcription factors T-bet, Gata3, and Rorγt. The anti-inflammatory property of SHC is highlighted through its influence on cytokine production, particularly in the NF-κB pathway, and the attenuation of Toll-like receptor (TLR) signaling. The results reveal that SHC acts as both an immunostimulator and an inhibitor of hyperimmune reactions, showcasing its potential therapeutic applications in conditions involving dysregulated immune responses such as autoimmune diseases and inflammatory disorders. This positions SHC as a promising candidate for the development of functional ingredients with diverse applications encompassing the realms of food, pharmaceuticals, and cosmetics. © 2024

关键词： Celluclast Concanavalin A S. horneri Splenocytes

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Comparative transcriptomic and molecular interaction analysis of olive polyphenols: Unraveling their mechanisms in immune regulation and metabolic processes in adipocytes

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Computers in Biology and Medicine 2025年 194卷

作者： Rui Wang Munkhzul Ganbold Farhana Ferdousi Hiroko Isoda Tsukuba Life Science Innovation Program (T-LSI) Graduate School of Science and Technology University of Tsukuba Tsukuba 305-8577 Japan Open Innovation Laboratory for Food and Medicinal Resource Engineering (FoodMed-OIL) National Institute of Advanced Science and Technology (AIST) Tsukuba Japan Institute of Life and Environmental Sciences University of Tsukuba 305-8577 Japan Alliance of Research on the Mediterranean and North Africa (ARENA) University of Tsukuba Tsukuba 305-8577 Japan

Olive polyphenols, including oleacein, oleocanthal, and oleuropein, have demonstrated potential benefits in mitigating the risk of metabolic diseases such as obesity and inflammation by improving glycemic control, reducing blood pressure, and lowering inflammation. This study provides a comprehensive comparative analysis of these compounds using human adipose-derived stem cells (hASCs). Whole-transcriptome analysis was employed to investigate the compounds' effects on adipocytes, focusing on immune system and metabolic pathways. A protein-protein interaction (PPI) network identified key targets and pathways. Oleacein uniquely enriched the PI3K-AKT pathway and demonstrated distinct regulation of inflammation and metabolism. The PPI network pinpointed growth hormone receptor (GHR) and interleukin-6 receptor (IL6R) as significant targets. Quantitative RT-qPCR analysis showed that oleacein significantly increased IL6R expression, while oleocanthal and oleuropein had no effect. GHR expression was also elevated by oleacein, although without statistical significance. Physicochemical properties of the compounds were analyzed for drug development potential. Molecular docking simulations indicated superior binding affinities for oleacein with GHR and IL6R, supported by surface plasmon resonance (SPR) assays, which confirmed stable interactions with both receptors. This study is the first to integrate transcriptomic, molecular, and structural analyses of these bioactive olive-derived compounds. Oleacein emerged as a promising candidate for therapeutic development, with unique molecular interactions and regulatory effects on adipocyte immune and metabolic processes. These findings provide a foundation for future investigations into oleacein's role in treating metabolic and inflammatory disorders.

关键词： Polyphenols Oleacein Adipocyte OLE oleacein OLT oleocanthal OLU oleuropein DEG differential expressed genes hASCs human adipose-derived stem cells GOBP gene ontology biological process PPI protein-protein network GHR growth hormone receptor IL6R interleukin-6 receptor SPR Surface Plasmon Resonance

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Hatching performances of native chicken supplemented L-arginine in ration and in Ovo injection

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AIP Conference Proceedings 2023年第1期2628卷

作者： I. Muing W. Pakiding S. Purwanti Student of Animal Husbandry Science and Technology Study Program Post Graduate School Hasanuddin University Makassar Indonesia Department of Animal Production Faculty of Animal Husbandry Hasanuddin University Makassar Indonesia Department of Animal Nutrition Faculty of Animal Husbandry Hasanuddin University Makassar Indonesia

This study aims to determine the effect of supplemented by L-Arginine in ration and Treated by L-Arginine in-ovo injection on the hatching performance of native chickens. This study used 60 fertile eggs obtained from hens supplemented by 0% L-Arginine in ration and 60 fertile eggs obtained from hens supplemented by 0.25% L-Arginine in ration. Eggs are arranged by Randomized Block Design with 4 treatments and 3 groups. The treatment consists of P0 (Control=Ration+0% L-Arginine and no L-Arginine injection), P1 (Ration+0% L-Arginine and 2% L-Arginine injection), P2 (Ration+0.25% and without L-Arginine injection), and P3 (Ration+0.25% and injection 2% L-Arginine). The results showed that supplemented by L-Arginine in ration and Treated by L-Arginine in-ovo injection no significant (P>0.05) on the hatching performance of native chickens. We conclude that supplemented by L-Arginine in ration and Treated by L-Arginine in-ovo injection no significant on hatching performance of native chickens although there is a tendency that supplemented of the L-Arginine in ration and Treated by L-Arginine in-ovo injection shows a better trend.

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The Effect of Guava on the Improvement of Lipid Profile in Hypercholesterolemic Rats 1

The Effect of Guava on the Improvement of Lipid Profile in H...

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1st International Conference on Life science and technology, ICoLiST 2018

作者： Maryanto, Sugeng Marsono, Yustinus Department of Nutrition Faculty of Health Science Universitas Ngudi Waluyo Jl. Diponegoro 186 Semarang Indonesia Department of Food Science Post-Graduate Program Gadjah Mada University Jl. Flora No. 1 Bulaksumur Yogyakarta Indonesia

Red guava is a fruit species with high vitamin C content and the highest fibers, in particular, soluble fiber (pectin) among tropical fruits and cereals. The soluble fiber is hypocholesterolemic in the body. Therefore, it has the potential to reduce cholesterol content. This study aimed to assess the potential of red guava in reducing cholesterol content in hypocholesterolemic rats. This study applied a pure experiment using a randomized pretestposttest group design on hypocholesterolemic Sprague Dawley rats. The rats were fed with 0.72 g of red guava and pectin supplement as a comparison. The total cholesterol content, LDL, HDL and triglyceride were measured by CHOD-PAP and GPO-PAP methods. Data analysis used t-test and ANOVA with significance rate of 0.05. Red guava intake to the hypocholesterolemic rats significantly reduced the contents of: total cholesterol to 57.8 mg/dL (32%), LDL to 25.5 mg/dL (43%), triglyceride to 19.7 mg/dL (18%). Conversely, it significantly increased HDL content to 10.6 mg/dL (18%). The red guava has proven to give hypocholesterolemic effect by reducing the total cholesterol LDL and triglyceride;Conversely, it significantly increased HDL. © 2019 IOP Publishing Ltd. All rights reserved.

关键词： Fatty acids

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The Atherogenic Index of Plasma Treated with Red Guava (Psidium guajava L.) 1

The Atherogenic Index of Plasma Treated with Red Guava (Psid...

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1st International Conference on Life science and technology, ICoLiST 2018

作者： Maryanto, Sugeng Marsono, Y. Department of Nutrition Faculty of Health Science Universitas Ngudi Waluyo Jl. Diponegoro 186 Semarang Indonesia Department of Food Science Post-Graduate Program Gadjah Mada University Jl. Flora No. 1 Bulaksumur Yogyakarta Indonesia

Red guava contains fiber especially high soluble fiber (pectin). Soluble fiber in the body is hypocholesterolemia. This research aimed to know the effect of administering red guava on AIP (Atherogenic Index of Plasma) in hypocholesterolemia rats. This research was a pure experiment using the design of randomized pretest-posttest control group design to Sprague Dawley rats made into hypocholesterolemia. The rats were divided into four groups: group 1 given standard food, group 2, 3, and 4 given high cholesterol food. Group 3 and 4 were added with red guava powder as many as 0.72 g and pectin equal to the one in red guava powder. Lipid profile was checked by using Enzymatic Colorimetric Test CHOP-PAP and GPO-PAP including the rate of total cholesterol, LDL, HDL, and triglycerides. AIP was counted based on log (TG/HDL). The data analysis used t-test and ANOVA with a 0.05 significance level. The administration of red guava in hypocholesterolemia rats was significantly proven to be able to lower lipid profile by lowering total cholesterol (32%), LDL (43%), triglycerides (18%),and by increasing HDL (18%). These results were similar to the decrease by administering pectin as many as 32%, 47%, and 20% respectively. The results of counting AIP showed that the administration of red guava and pectin could lower AIP score significantly as many as 0.16 and 0.17 respectively which increased in the groups getting high cholesterol food. The administration of red guava in hypocholesterolemia rats was proven to be able to lower AIP. © 2019 IOP Publishing Ltd. All rights reserved.

关键词： Rats

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Preliminary study: Production and quality of signal grass (Brachiaria decumbens) on the post mining land

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AIP Conference Proceedings 2023年第1期2628卷

作者： N. A. A. Toputri R. A. Habibi E. Harri Sema R. F. Utamy S. Hasan Animal Husbandry and Technology Post-Graduate Program Hasanuddin University Makassar Indonesia Nursery PT. Vale Sorowako East Luwu South Sulawesi Indonesia Animal Nutrition and Feed Technology Faculty of Agriculture Puangrimaggalatung University Sengkang Indonesia Faculty of Animal Science Universitas Hasanuddin Makassar South Sulawesi Indonesia

The post-mining land decrease soil fertility. Soil fertility is required for plant growth. One way to minimize this soil fertility is by planting grass and legume in a mixed-cropping system. This preliminary study was aimed to evaluate the production and quality of signal grass and legume on the post-mining land of PT Vale Indonesia, Tbk. This study used a descriptive/survey method such as direct measurements and observations in the field. The results showed the average production of fresh weight (7.5 tons/Ha), dry matter (1.5 tons/Ha), chlorophyll (30 mg/g leaves), and leaf area (22.5 cm) of signal grass without legumes. Meanwhile, the average production of fresh weight (15.80 tons/Ha), dry matter (3.16 tons/Ha), chlorophyll (38 mg/g leaves), and leaf area (35.6 cm) of signal grass with legumes.

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Protective effect and antioxidative efficacy of Moringa stenopetala leaf extract in BV-2 microglial cell

Food Chemistry Advances

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food Chemistry Advances 2024年 5卷

作者： Adefegha, Stephen Adeniyi Mostardeiro, Vitor Morsch, Vera Maria Morel, Ademir F. Da Cruz, Ivana Beatrice Manica Somacal, Sabrina Oboh, Ganiyu Schetinger, Maria Rosa Chitolina Functional Foods Nutraceuticals and Phytomedicine Laboratory Department of Biochemistry Federal University of Technology P. M. B. 704 Akure Nigeria Graduate Program in Toxicological Biochemistry Department of Biochemistry and Molecular Biology Center of Natural and Exacts Sciences Federal University of Santa Maria RS Santa Maria 97105-900 Brazil Department of Chemistry Center of Natural and Exacts Sciences Federal University of Santa Maria RS 97105-900 Brazil Biogenomics Laboratory Department of Morphology Federal University of Santa Maria RS 97105-900 Brazil Department of Food Science and Technology Center for Rural Sciences Federal University of Santa Maria RS 97105-900 Brazil

Moringa stenopetala is often consumed as food and used in folkloric medicine for the management of several diseases including neurodegenerative diseases. This study investigated the protective effect and antioxidant efficacy of aqueous extract of Moringa stenopetala in BV-2 microglial cells. Aqueous extracts of M. stenopetala were prepared, lyophilized and reconstituted in 0.5% dimethylsulphoxide (DMSO). Cells were treated with M. stenopetala extracts (0.1–100 µg/ml) for cell viability assay and nitric oxide (NO) production tests. However, M. stenopetala extract (50 µg/ml) was used in the treatment of cells for the determination of protein carbonyl content and reactive oxygen species (ROS) level. Incubation of BV-2 microglia cell with M. stenopetala extract maintained cell viability, diminished NO and ROS levels, and reduced protein carbonyl contents. Chlorogenic acid, rutin, kaempferol and quercetin derivatives were the main phenolic compounds identified in M. stenopetala leaf extract. In conclusion, this study suggests that M. stenopetala extract is rich in antioxidant and contains bioactive neuroprotective agents. © 2024 The Author(s)

关键词： Antioxidant BV-2 microglial cell Cell viability Moringa stenopetala Oxidative stress

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Retraction notice to "Organic composts as A vehicle for the entry of microplastics into the environment: A comprehensive review" [Sci. Total Environ. 892 (2023) 164758]

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The science of the total environment 2024年 957卷 177731页

作者： Van-Re Le Minh-Ky Nguyen Hoang-Lam Nguyen Chitsan Lin Md Refat Jahan Rakib Van-Anh Thai Van-Giang Le Guilherme Malafaia Abubakr M Idris Ho Chi Minh City University of Food Industry (HUFI) 140 Le Trong Tan Street Tan Phu District Ho Chi Minh City 700000 Viet Nam. Faculty of Environment and Natural Resources Nong Lam University of Ho Chi Minh City Hamlet 6 Linh Trung Ward Thu Duc City Ho Chi Minh City 700000 Viet Nam Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. Department of Civil Engineering McGill University Montreal Canada. Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan Department of Marine Environmental Engineering National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. Department of Fisheries and Marine Science Faculty of Science Noakhali Science and Technology University Noakhali 3814 Bangladesh. Institute of Aquatic Science and Technology National Kaohsiung University of Science and Technology Kaohsiung City 81157 Taiwan. Central Institute for Natural Resources and Environmental Studies Vietnam National University Hanoi 111000 Viet Nam. Post-Graduation Program in Ecology Conservation and Biodiversity Federal University of Uberlândia Uberlândia MG Brazil Post-Graduation Program in Biotechnology and Biodiversity Federal University of Goiás Goiânia GO Brazil Post-Graduation Program in Conservation of Cerrado Natural Resources Goiano Federal Institute Urutaí GO Brazil. Department of Chemistry College of Science King Khalid University 61431 Abha Saudi Arabia Research Center for Advanced Materials Science (RCAMS) King Khalid University Abha 61421 Saudi Arabia.

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Information technology of Motor Vehicle Databases Use to Prevent Terrorist Emergencies

Information Technology of Motor Vehicle Databases Use to Pre...

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International Conference on Advanced Computer Information Technologies (ACIT)

作者： Yuliia Honcharenko Natalia Kasatkina Yurii Maslyiak Bogdan Maslyiak Lyudmyla Honchar Department of Information Technologies European University Kyiv Ukraine Division of Doctoral and Post-Graduate National University of Food Technology Kyiv Ukraine Department of Computer Science Ternopil National Economic University Ternopil Ukraine

ISBN: (数字)9781728167602

ISBN: (纸本)9781728167619

Based on the analysis of gradation scheme of motor vehicles situational background near a protected object of a critical infrastructure, the process of data collecting and filling the database and knowledgebase of the protected object main server as well as the procedure of violators' identification and collecting data on them is considered in the paper. After that, the structure of the control algorithm is described. The algorithm defines the application of information technology for the use of motor vehicles databases to prevent the terrorist emergencies.

关键词： Databases Terrorism Critical infrastructure Servers Standards Information technology Vehicle dynamics

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