It is presented a state-space realization approach for identification of a pilot scale heat exchanger plant. The proposed methodology is a computational efficient way to estimate state-space models from experimental d...
Extraction of electromagnetic energy by an antenna from impinging external radiation is at the basis of wireless communications and wireless power transfer (WPT). The maximum of transferred energy is ensured when the ...
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Extraction of electromagnetic energy by an antenna from impinging external radiation is at the basis of wireless communications and wireless power transfer (WPT). The maximum of transferred energy is ensured when the antenna is conjugately matched, i.e., when it is resonant and it has an equal coupling with free space and its load. This condition, however, can be easily affected by changes in the environment, preventing optimal operation of a WPT system. Here, we introduce the concept of coherently enhanced WPT that allows us to bypass this difficulty and achieve dynamic control of power transfer. The approach relies on coherent excitation of the waveguide connected to the antenna load with a backward propagating signal of specific amplitude and phase. This signal creates a suitable interference pattern at the load resulting in a modification of the local wave impedance, which in turn enables conjugate matching and a largely increased amount of extracted energy. We develop a simple theoretical model describing this concept, demonstrate it with full-wave numerical simulations for the canonical example of a dipole antenna, and verify experimentally in both near-field and far-field regimes.
Reporting-Guidelines in Medicine play an important role in promoting the quality of reports in health-related research. For instance, a poorly reported research may induce misinterpretation and inappropriate clinical ...
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PPFIA3 encodes the protein-tyrosine phosphatase, receptor-type, F-polypeptide-interacting-protein-alpha-3 (PPFIA3), which is a member of the LAR-protein-tyrosine phosphatase-interacting-protein (liprin) family involve...
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PPFIA3 encodes the protein-tyrosine phosphatase, receptor-type, F-polypeptide-interacting-protein-alpha-3 (PPFIA3), which is a member of the LAR-protein-tyrosine phosphatase-interacting-protein (liprin) family involved in synapse formation and function, synaptic vesicle transport, and presynaptic active zone assembly. The protein structure and function are evolutionarily well conserved, but human diseases related to PPFIA3 dysfunction are not yet reported in OMIM. Here, we report 20 individuals with rare PPFIA3 variants (19 heterozygous and 1 compound heterozygous) presenting with developmental delay, intellectual disability, hypotonia, dysmorphisms, microcephaly or macrocephaly, autistic features, and epilepsy with reduced penetrance. Seventeen unique PPFIA3 variants were detected in 18 families. To determine the pathogenicity of PPFIA3 variants in vivo, we generated transgenic fruit flies producing either human wild-type (WT) PPFIA3 or five missense variants using GAL4-UAS targeted gene expression systems. In the fly overexpression assays, we found that the PPFIA3 variants in the region encoding the N-terminal coiled-coil domain exhibited stronger phenotypes compared to those affecting the C-terminal region. In the loss-of-function fly assay, we show that the homozygous loss of fly Liprin-α leads to embryonic lethality. This lethality is partially rescued by the expression of human PPFIA3 WT, suggesting human PPFIA3 function is partially conserved in the fly. However, two of the tested variants failed to rescue the lethality at the larval stage and one variant failed to rescue lethality at the adult stage. Altogether, the human and fruit fly data reveal that the rare PPFIA3 variants are dominant-negative loss-of-function alleles that perturb multiple developmental processes and synapse formation.
In this paper, three configurations of three-phase ac-dc cascaded converters are presented. They are referred as basic configurations, and are composed by two three-phase bridges, where the second bridge is cascaded t...
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ISBN:
(纸本)9781509029990
In this paper, three configurations of three-phase ac-dc cascaded converters are presented. They are referred as basic configurations, and are composed by two three-phase bridges, where the second bridge is cascaded to the first by means of a three-phase injection transformer. Basic configurations have one bidirectional option (composed only by IGBT switches), and two unidirectional ones (composed by IGBT and diodes). Their generalizations, which are composed by an indefinite number of cascaded three-phase bridges, are also proposed. Each additional cascaded bridge is a three-phase IGBT bridge and requires one additional three-phase injection transformer. Transformers turns ratios are calculated in order to maximize the number of levels produced in the ac side of each rectifier, enhancing power quality. Basic configurations are compared by means of simulations between themselves and with the conventional three-phase IGBT bridge, to show that proposed multilevel rectifiers present better performance in terms of ac power quality drew from the ac source, with lower semiconductor losses. Experimental results are also exposed for the basic configurations to validate them and show their feasibility.
Agent behaviors in simulation systems are related to fundamental capabilities of realistically developing (semi) autonomous navigation actions. This is particularly important when dealing with the implementation of Co...
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Agent behaviors in simulation systems are related to fundamental capabilities of realistically developing (semi) autonomous navigation actions. This is particularly important when dealing with the implementation of computer Generated Forces (CGFs) for simulation systems in tactical military training applications. Moreover, these systems take into consideration the particularities of the domain-specific simulation tasks and the numerous heterogeneous CGFs inserted on them in order to generate better knowledge and learning experience to simulation system users. Based on these reasons, this paper reviews recurrent navigation problems as to propose a task-oriented and parameterized (semi) autonomous navigation framework to deal with CGF navigation needs in military simulation. Combining global and local navigation techniques, and controlled transition between alternative degrees of navigation autonomy, the framework aims to overcome the challenges of implementing customizable CGF navigation behaviors and, at the same time, to allow interaction with both users and other simulation systems in distributed simulation settings. A case study is presented in which the proposed techniques are analyzed in a domain-specific simulation problem providing evidence of their suitability to address the studied military simulation problems.
Telemedicine offers the ability to provide real-time medical support, education, and care to remote and austere locations under limited bandwidth restrictions. These types of communication channels can easily be overw...
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Telemedicine offers the ability to provide real-time medical support, education, and care to remote and austere locations under limited bandwidth restrictions. These types of communication channels can easily be overwhelmed and delays or interruptions make communication difficult, if not impossible. These interruptions destroy the temporal orientation of communication resulting in significant cognitive loading. The objective of this research was to lower cognitive load and minimize digital communication bandwidth by developing a priority model from perceptual quality and content focus of telemedical video. H.264/AVC encoding was used to encode two types of medical context with varying bitrates, frame rates, and frame sizes. Telemedical video contexts were room awareness, and medical procedure. Objective quality and subjective quality tests were performed using Structural Similarity (SSIM) and perceptual feedback, respectively. The objective of this research is to develop context specific telemedicine communication models for the highest perceptual quality for available bandwidth for the purpose of increased temporal orientation and decreased cognitive load. Our research presents a method to select the best encoding parameters (maximum bitrate, frame rate and frame size) for the medical context to minimize bandwidth and maintain diagnostic and education quality.
The human visual system employs a mechanism of visual attention, which selects only part of the incoming information for further processing. Through this mechanism, the brain avoids overloading its limited cognitive c...
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Image retargeting has seen many applications in areas such as content adaptation for small displays and thumbnailing for image database browsing. Most retargeting methods, however, are too expensive computationally to...
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The conjugate gradient (CG) method is commonly used for the relatively-rapid solution of least squares problems. In image reconstruction, the problem can be ill-posed and also contaminated by noise;due to this, approa...
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