This study aimed to evaluate the anti-hyperglycemic and antioxidant role of Actinidia deliciosa(kiwifruits)aqueous extract in streptozotocin-treated *** were distributed into;control,*** aqueous extract(ADAE;1 g/kg or...
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This study aimed to evaluate the anti-hyperglycemic and antioxidant role of Actinidia deliciosa(kiwifruits)aqueous extract in streptozotocin-treated *** were distributed into;control,*** aqueous extract(ADAE;1 g/kg orally),streptozotocin(STZ;50 mg/kg,i.p,single dose),and STZ plus ADAE,*** showed that ADAE had high antioxidant and radical scavenging *** in blood sugar level,lipid peroxidation(LPO),kidney function biomarkers,and perturbations in hematological parameters were observed in diabetic ***,enzymatic and non-enzymatic antioxidants,protein content,and alkaline phosphatase(ALP)activity ***,histological,immunohistochemical alpha-smooth muscle actin immunoreactivity(α-SMA-ir)and histochemical(collagen,total protein,DNA,and RNA)alterations were observed in rat ***,STZ produced upregulation of inflammatory associated genes(tumor necrosis factor-alpha;TNF-αand transforming growth factorβ1;TGF-β1)and triggered apoptosis by upregulating apoptotic related gene[Bcl2-associated X protein(Bax)]and downregulating anti-apoptotic related gene B-cell lymphoma-2(Bcl-2)based on real-time PCR ***,diabetic rats administered with ADAE showed significant restoration in LPO,antioxidant status,and biochemical indices besides tissue architecture,and genes improvement regarding STZ ***,*** has a valuable ameliorative infl uence and can restore glucose levels and improve kidney dysfunction in diabetic rats.
Four highly oxidized pimarane diterpenoids were isolated from Kaempferia takensis *** A-C pos-sess a tetracyclic ring with either a fused tetrahydropyran or tetrahydrofuran *** D has an unusual rearranged A/B ring spi...
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Four highly oxidized pimarane diterpenoids were isolated from Kaempferia takensis *** A-C pos-sess a tetracyclic ring with either a fused tetrahydropyran or tetrahydrofuran *** D has an unusual rearranged A/B ring spiro-bridged pimarane framework with a C-10 spirocyclic junction and an adjacent 1-methyltri-cyclo[3.2.1.02,7]octene *** characterization was achieved using spectroscopic analysis,DP4+and ECD calculations,as well as X-ray crystallography,and their putative biosynthetic pathways have been *** B showed significant potency in inhibiting nitric oxide production with an IC50 value of 0.69μ*** docking provided some perspectives on the action of kaemtakol B on iNOS protein.
This study, using the Naïve Bayes classifier, proposes a new descriptive model for conducting a comparative review analysis on the tourism domain. The proposed model seeks to improve the understanding of tourists...
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This study, using the Naïve Bayes classifier, proposes a new descriptive model for conducting a comparative review analysis on the tourism domain. The proposed model seeks to improve the understanding of tourists' experiences by visually representing their opinions between various tourist destinations. The model predicts the sentiment of tourist reviews using the Naive Bayes classifier, which is then used to generate visualizations that facilitate comparative analysis. The comparison takes two tourism sites as experimental examples. The results, in terms of accuracy, show 80% and 64% for the first and the second site respectively. The study discusses the model's implementation, effectiveness, and potential applications in the tourism industry. The findings of the study suggest that the proposed model can provide valuable insights into tourist experiences and help tourism stakeholders, such as the managements of tourism sites, the future or soon coming tourists to make informed decisions based on comparative analysis.
Oceanic Rossby waves play a crucial role in shaping the physical and biological dynamics of both open and coastal oceans, especially within the tropical band spanning between the 10°S and 10°N parallels. Yet...
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The hydrolysis of DNA serves as the foundational principle for gene engineering that enable precise gene cleavage at the molecular level. This process typically occurs in biological nucleases, which exhibit nucleobase...
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Transposable elements(TEs)are a major force in the production of new alleles during domestication;nevertheless,their use in association studies has been limited because of their *** have developed a TE genotyping pipe...
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Transposable elements(TEs)are a major force in the production of new alleles during domestication;nevertheless,their use in association studies has been limited because of their *** have developed a TE genotyping pipeline(TEmarker)and applied it to whole-genome genome-wide association study(GWAS)data from 176 Oryza sativa *** accessions to identify genetic elements associated with specific agronomic *** markers recovered a large proportion(69%)of single-nucleotide polymorphism(SNP)-based GWAS peaks,and these TE peaks retained ca.25%of the *** use of TEs in GWASs may reduce false positives associated with linkage disequilibrium(LD)among SNP markers.A genome scan revealed positive selection on TEs associated with agronomic *** found several cases of insertion and deletion variants that potentially resulted from the direct action of TEs,including an allele of LOC_Os11g08410 associated with plant height and panicle length ***,these findings reveal the utility of TE markers for connecting genotype to phenotype and suggest a potential role for TEs in influencing phenotypic variations in rice that impact agronomic traits.
Disinfection by UV radiation has been analyzed as an effective and more advantageous way for the inactivation of microorganisms in water, among the options of UV disinfection it is worth mentioning the LED technology ...
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All-sky medium-energy gamma-ray observations are essential to deepen our understanding of physics in extreme astronomical objects such as gamma-ray bursts and active galactic nuclei. Those observations are also highly...
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Studies have evaluated the impact of environmental exposure to neurotoxic metals on developmental delays (DDs). However, comprehensive understanding regarding the associations between parental and postnatal exposure t...
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