检索结果-内蒙古大学图书馆

3D printed bioabsorbable composite scaffolds of poly (lactic acid)-tricalcium phosphate-ceria with osteogenic property for bone regeneration

引用

Biomaterials and Biosystems 2024年 13卷 100086页

作者： Harb, Samarah V. Kolanthai, Elayaraja Pugazhendhi, Abinaya S. Beatrice, Cesar A.G. Pinto, Leonardo A. Neal, Craig J. Backes, Eduardo H. Nunes, Ana C.C. Selistre-de-Araújo, Heloisa S. Costa, Lidiane C. Coathup, Melanie J. Seal, Sudipta Pessan, Luiz A. Department of Materials Engineering (DEMa) Federal University of Sao Carlos (UFSCar) SP São Carlos Brazil Advanced Materials Processing and Analysis Center Department of Materials Science and Engineering University of Central Florida Orlando FL United States Biionix Cluster College of Medicine University of Central Florida Orlando FL United States Graduate Program in Materials Science and Engineering Department of Materials Engineering (DEMa) Federal University of São Carlos (UFSCar) SP São Carlos Brazil Department of Physiological Sciences Federal University of São Carlos (UFSCar) SP São Carlos Brazil

The fabrication of customized implants by additive manufacturing has allowed continued development of the personalized medicine field. Herein, a 3D-printed bioabsorbable poly (lactic acid) (PLA)- β-tricalcium phosphate (TCP) (10 wt %) composite has been modified with CeO₂ nanoparticles (CeNPs) (1, 5 and 10 wt %) for bone repair. The filaments were prepared by melt extrusion and used to print porous scaffolds. The nanocomposite scaffolds possessed precise structure with fine print resolution, a homogenous distribution of TCP and CeNP components, and mechanical properties appropriate for bone tissue engineering applications. Cell proliferation assays using osteoblast cultures confirmed the cytocompatibility of the composites. In addition, the presence of CeNPs enhanced the proliferation and differentiation of mesenchymal stem cells;thereby, increasing alkaline phosphatase (ALP) activity, calcium deposition and bone-related gene expression. Results from this study have shown that the 3D printed PLA-TCP-10%CeO₂ composite scaffold could be used as an alternative polymeric implant for bone tissue engineering applications: avoiding additional/revision surgeries and accelerating the regenerative process. © 2023

关键词： Additive manufacturing Biomaterial Bone tissue engineering Ceria nanoparticle Polymer-matrix composites

来源：评论

学校读者我要写书评

暂无评论

Electronic and Optical Excitations in van der Waals materials from a Non-Empirical Wannier-Localized Optimally-Tuned Screened Range-Separated Hybrid Functional

arXiv

引用

arXiv 2024年

作者： Camarasa-Gómez, María Gant, Stephen E. Ohad, Guy Neaton, Jeffrey B. Ramasubramaniam, Ashwin Kronik, Leeor Department of Molecular Chemistry and Materials Science Weizmann Institute of Science Rehovoth7610001 Israel Department of Physics University of California BerkeleyCA94720 United States Materials Sciences Division Lawrence Berkeley National Laboratory BerkeleyCA94720 United States Kavli Energy NanoSciences Institute at Berkeley University of California BerkeleyCA94720 United States Department of Mechanical and Industrial Engineering University of Massachusetts Amherst AmherstMA01003 United States Materials Science and Engineering Graduate Program University of Massachusetts AmherstMA01003 United States

Accurate prediction of electronic and optical excitations in van der Waals (vdW) materials is a long-standing challenge for density functional theory. The recently proposed Wannier-localized optimally-tuned screened range-separated hybrid (WOT-SRSH) functional has proven successful in non-empirical determination of electronic band gaps and optical absorption spectra for various covalent and ionic crystals. However, for vdW materials the tuning of the material- and structure-dependent functional parameters has, until now, only been attained semi-empirically. Here, we present a non-empirical WOT-SRSH approach applicable to vdW materials, with the optimal functional parameters transferable between monolayer and bulk. We apply this methodology to prototypical vdW materials: black phosphrous, moldybdenum disulfide, and hexagonal boron nitride (in the latter case including zero-point renormalization). We show that the WOT-SRSH approach consistently achieves accuracy levels comparable to experiments and ab initio many-body perturbation theory (MBPT) calculations for band structures and optical absorption spectra, both on its own and as an optimal starting point for MBPT calculations. Copyright © 2024, The Authors. All rights reserved.

关键词： Energy gap

来源：评论

学校读者我要写书评

暂无评论

Investigation of manufacturing conditions of single roll rapidly solidified ribbon for anode materials of magnesium rechargeable batteries

引用

Keikinzoku/Journal of Japan Institute of Light Metals 2023年第11期73卷 537-544页

作者： Kirimoto, Yuichi Fuke, Kousuke Tsukeda, Tadayoshi Aida, Tetsuo Nemoto, Yasunori Ikeda, Minoru Tabata, Hironobu Kurihara, Hideki Suzuki, Mayumi Department of Nano and Functional Material Science Graduate School of Science and Engineering for Education University of Toyama 3190 Gofuku Toyama-shi-shiToyama Toyama930-8555 Japan Program of Materials Science and Engineering Studies in Science and Engineering Graduate School of Science and Engineering University of Toyama Toyama-shi-shiToyama Toyama Japan Faculty of Sustainable Design Academic Assembly University of Toyama Toyama-shi Toyama-shi-shiToyama Toyama Japan FLOW Science JAPAN Shizuoka Hamamatsu-shi Japan CHUETSU METAL WORKS CO. LTD Nakaniikawa-gun Toyama Japan Saitama Industrial Technology Center Saitama Kawaguchi-shi Japan Department of Mechanical Systems Engineering Faculty of Engineering Toyama Prefectural University Imizu-shi Toyama Japan

Magnesium rechargeable batteries are attracting attention as next-generation rechargeable batteries because of their resource abundance, cost, safety, and high electrical capacity per volume compared to conventional lithium-ion rechargeable batteries. Our joint research team focused not only on the electrochemically active magnesium composition of ribbon for the negative electrode materials of magnesium rechargeable batteries but also on the production process, focused on the single roll type liquid quenching and rapid solidification method, which can be produced at a lower cost. In this study, the optimal processing conditions were examined by comparing CAE analysis with ribbon actually manufactured, with the aim of further improving manufacturing conditions using the same method, such as length discontinuities, thickness, and surface properties of ribbon. We specifically various process parameters such as injection pressure and roll peripheral speed for evaluation. As a result, several linear cracks were observed on the surface of the ribbon as the peripheral speed increased and as the Gap became wider, and the surface properties tended to deteriorate. Also, It was found that the dominant factor in the length of the ribbon was the peripheral speed. As the peripheral speed increased, the length of the ribbon tended to increase. © 2023 Japan Institute of Light Metals. All rights reserved.

关键词： Surface properties

来源：评论

学校读者我要写书评

暂无评论

MOF-catalyzed hydroxyalkylation-alkylation reaction for the controlled synthesis of furan oligomers

引用

Applied Catalysis A: General 2024年 669卷

作者： Atayde, Eduardo C. Matsagar, Babasaheb M. Wang, Yu-Cheng Wu, Kevin C.-W. Molecular Science and Technology Program Taiwan International Graduate Program Academia Sinica No. 128 Sec. 2 Academia Road Taipei11529 Taiwan Department of Chemistry National Tsing Hua University No. 101 Sec. 2 Kuang-Fu Road Hsinchu30013 Taiwan Department of Chemical Engineering National Taiwan University No. 1 Sec. 2 Roosevelt Road Taipei10617 Taiwan Department of Chemical Engineering and Materials Science Yuan Ze University Taoyuan Chung-Li Taiwan

Hydroxyalkylation-alkylation (HAA) reaction is a type of C-C coupling technique utilized in the production of furan oligomers, which are potential biofuel precursors. In this study, we present the first application of an acidic MOF, Sulfated MOF-808, in catalyzing the HAA reactions of a series of furan oligomers with high yield and selectivity. Specifically, we focused on the optimization of the HAA between 5-methylfurfural (5-MFUR) and 2-methylfuran (2-MF) by varying different reaction conditions, which afforded a quantitative yield reaching 97% while preventing the self-condensation of 2-MF. The catalyst was also found to be recyclable and can be reused without significant loss in its activity. Lastly, we extended the substrate scope to include benzene-based electrophiles, thereby further proving the versatility of the Sulfated MOF-808 catalyst in the HAA reactions of a variety of starting materials. © 2023 Elsevier B.V.

关键词： Catalysis

来源：评论

学校读者我要写书评

暂无评论

Solid waste management in the paper industry 5

Solid waste management in the paper industry

引用

5th International Conference on Energy, Environmental and Information System, ICENIS 2020

作者： Devichi Wibowo, Isabella Purwanto, P. Suherman, S. Master Program of Environmental Science Post-Graduate Studies Universitas Diponegoro Semarang Indonesia Department of Chemical Engineering Faculty of Engineering Universitas Diponegoro Semarang Indonesia

The industry developed rapidly since the Industrial Revolution in the 18th century. The side effect of industrial development was a large amount of non-hazardous waste and hazardous waste. All of this waste must be managed properly so that environmental sustainability is maintained and does not cause harm or problems to the community. A review will be conducted from various research journals in various countries and the types of waste also vary, namely plastic, pulp and paper industry waste, and other solid waste. A comparison of solid waste management will be carried on to reduce the generation of waste in the environment. © The Authors, published by EDP sciences, 2020.

关键词： Solid wastes

来源：评论

学校读者我要写书评

暂无评论

Top-Down Fabrication of Diamond Nanostructures

SSRN

引用

SSRN 2024年

作者： Biswas, Abhijit Li, Chenxi Pieshkov, Tymofii Mei, Zhaobo Xu, Mingfei Li, Tao Murukeshan, Jishnu Vajtai, Robert Zhao, Yuji Ajayan, Pulickel M. Department of Materials Science and NanoEngineering Rice University HoustonTX77005 United States Applied Physics Graduate Program Smalley-Curl Institute Rice University HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States

Diamond nanostructures can have exciting applications in electronics and thermal management, but their controlled fabrication can be challenging. Here, we present a top-down approach for the fabrication of diamond nanorod (DNR) clusters, via use of metal masks (Al, Ag, Au, and Cr) and reactive-ion etching (RIE). Prolonged RIE on Ag and Cr masks yields distinct etching profiles, and DNR clusters are selectively formed from Ag masks, with individual nanorods having dimensions of ~100 nm diameter and ~1.5 µm length. Detailed electron microscopy shows thin layer of amorphous carbon (a-C) around single crystalline DNR cores. Chemical analyses also show presence of oxygen on the surface of the DNRs. Fabrication of the DNR clusters with scalable top-down approach could lead to new nanodiamond-based applications. © 2024, The Authors. All rights reserved.

关键词： Nanorods

来源：评论

学校读者我要写书评

暂无评论

Neural Network for Classification of Mns Microinclusions in Steels

SSRN

引用

SSRN 2023年

作者： de Oliveira Filho, Marcos Fernando Amelio Briquet Caradec, Pierre D. Calsaverini, Rafael Spinelli, José Eduardo Ishikawa, Tomaz Toshimi Graduate Program in Materials Science and Engineering UFSCar SP São Carlos13565-905 Brazil Villares Metals S/A Sumaré SP São Paulo13178-902 Brazil Nubank SP São Paulo05409-000 Brazil Department of Materials Engineering UFSCar SP São Carlos13565-905 Brazil

The influence of MnS inclusions on steel properties is highly noticeable. Manual inclusions classification methods are the most used in laboratories and metallurgical sector industries because of their low cost, while automatic methods have high operating costs, which makes their use more restrict. Neural network models, on the other hand, are extremely advantageous for several applications. The present study is motivated by the use of a neural network model for classifying inclusions in steels. The aim is to achieve the highest possible accuracy in classifying the MnS inclusions severities (0, 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, and 4.5) using optical images captured from steel specimens. The results have showed that the classification of MnS severities was very sensitive to the database number of images. A 98% training accuracy was obtained by increasing the number of images from 3,156 to 4,136, mostly adding images for some severity levels. However, validation and test results were not satisfactory. As such, a severity re-categorization of the database was able to enhance the true positive values, with an error of 8%. In general, the neural network represented speed in decision making, proving to be a potential tool for classifying steel inclusions. © 2023, The Authors. All rights reserved.

关键词： Operating costs

来源：评论

学校读者我要写书评

暂无评论

Fucoxanthin induces human melanoma cytotoxicity by thwarting the JAK2/STAT3/BCL-xL signaling axis

引用

Environmental Toxicology 2024年第6期39卷 3356-3366页

作者： Kuo, Min-Yung Dai, Wen-Chyi Chang, Jie-Li Chang, Jo-Shu Lee, Tse-Min Chang, Chia-Che Pediatric Surgery Division Department of Surgery Tungs' Taichung MetroHarbor Hospital Taichung Taiwan Doctoral Program in Biotechnology Industrial Innovation and Management National Chung Hsing University Taichung Taiwan Taichung Municipal Taichung First Senior High School Taichung Taiwan Department of Chemical and Materials Engineering Research Center for Smart Sustainable Circular Economy Tunghai University Taichung Taiwan Department of Life Sciences National Chung Hsing University Taichung Taiwan Department of Marine Biotechnology and Resources National Sun Yat-sen University Kaohsiung Taiwan Graduate Institute of Biomedical Sciences Master Program in Precision Health Doctoral Program in Translational Medicine Rong Hsing Research Center for Translational Medicine The iEGG and Animal Biotechnology Research Center National Chung Hsing University Taichung Taiwan Department of Medical Laboratory Science and Biotechnology Asia University Taichung Taiwan Department of Medical Research China Medical University Hospital Taichung Taiwan Traditional Herbal Medicine Research Center Taipei Medical University Hospital Taipei Taiwan

Melanoma is the most lethal skin malignancy. Fucoxanthin is a marine carotenoid with significant anticancer activities. Intriguingly, Fucoxanthin's impact on human melanoma remains elusive. Signal Transducer and Activator of Transcription 3 (STAT3) represents a promising target in cancer therapy due to its persistent activation in various cancers, including melanoma. Herein, we revealed that Fucoxanthin is cytotoxic to human melanoma cell lines A2758 and A375 while showing limited cytotoxicity to normal human melanocytes. Apoptosis is a primary reason for Fucoxanthin's melanoma cytotoxicity, as the pan-caspase inhibitor z-VAD-fmk drastically abrogated Fucoxanthin-elicited clonogenicity blockage. Besides, Fucoxanthin downregulated tyrosine 705-phosphorylated STAT3 (p-STAT3 (Y705)), either inherently present in melanoma cells or inducible by interleukin 6 (IL-6) stimulation. Notably, ectopic expression of STAT3-C, a dominant-active STAT3 mutant, abolished Fucoxanthin-elicited melanoma cell apoptosis and clonogenicity inhibition, supporting the pivotal role of STAT3 blockage in Fucoxanthin's melanoma cytotoxicity. Moreover, Fucoxanthin lowered BCL-xL levels by blocking STAT3 activation, while ectopic BCL-xL expression rescued melanoma cells from Fucoxanthin-induced killing. Lastly, Fucoxanthin was found to diminish the levels of JAK2 with dual phosphorylation at tyrosine residues 1007 and 1008 in melanoma cells, suggesting that Fucoxanthin impairs STAT3 signaling by blocking JAK2 activation. Collectively, we present the first evidence that Fucoxanthin is cytotoxic selectively against human melanoma cells while sparing normal melanocytes. Mechanistically, Fucoxanthin targets the JAK2/STAT3/BCL-xL antiapoptotic axis to provoke melanoma cell death. This discovery implicates the potential application of Fucoxanthin as a chemopreventive or therapeutic strategy for melanoma management. © 2024 Wiley Periodicals LLC.

关键词： Carotenoids

来源：评论

学校读者我要写书评

暂无评论

Effect of double coating on microencapsulation of levofloxacin using the particles from gas-saturated solutions process as a controlled-release system

引用

Discover Chemistry 2025年第1期2卷 1-13页

作者： Sharmin, Tanjina Takeshita, Toshihiro Ouchi, Mikio Yoshida, Koji Znad, Hussein Saptoro, Agus Sarker, Zaidul Islam Irie, Keiichi Satho, Tomomitsu Nioh, Atsushi Masuda, Takaaki Muneyoshi, Yuuki Terayama, Suzuko Mishima, Kenji Department of Chemical Engineering Faculty of Engineering Fukuoka University Fukuoka Japan Research Institute of Composite Materials Fukuoka University Fukuoka Japan Resource Circulation Faculty of Environmental Engineering Fukuoka University Fukuoka Japan Faculty of Sciences Fukuoka University Fukuoka Japan Western Australian School of Mines: Minerals Energy and Chemical Engineering Faculty of Science and Engineering Curtin University Perth Australia Department of Chemical Engineering Faculty of Engineering Curtin Malaysia Graduate School Miri Sarawak Malaysia Department of State Program and Food Science Northern Marianas College Saipan USA Faculty of Pharmaceutical Sciences Fukuoka University Fukuoka Japan Yokohama Research Center Pola Chemical Industries Yokohama Japan

A novel double-coating technique was employed to encapsulate levofloxacin (LVF), a potent antibacterial drug, using the particles from gas-saturated solutions (PGSS) process to achieve extended release. The primary coating utilized glyceryl tristearate (GT), a lipid with a high melting point (72 °C), followed by a secondary coating with trimyristin (TM), a lipid with a lower melting point (52 °C). For comparison, a single-coating approach was also explored, using the biocompatible polymer poly-(ε-caprolactone) (PCL). The resulting particles were characterized for their shape, size, and LVF encapsulation efficiency, with confirmation of LVF entrapment provided by Fourier transform infrared (FTIR) spectroscopy, and X‐ray powder diffraction (XRD) analysis. The particles, with an average diameter of 95.3 ± 16.5 μm, exhibited an encapsulation efficiency of up to 92.1 ± 2.5%. Furthermore, in vitro release studies revealed that the double-coated microcapsules effectively suppressed the initial burst release and provided controlled, extended release of LVF (t30D = 36.3%), demonstrating the efficiency of this encapsulation method for prolonged drug delivery.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Big data in healthcare:Conceptual network structure,key challenges and opportunities

引用

Digital Communications and Networks 2023年第4期9卷 856-868页

作者： Leonardo B.Furstenaua Pedro Leivas Michele Kremer Sott Michael S.Dohan Jose Ricardo Lopez-Robles Manuel J.Cobo Nicola Luigi Bragazzi Kim-Kwang Raymond Choo Post-Graduate Program in Industrial Engineering Federal University of Rio Grande Do SulPorto Alegre90035-190Brazil University of Santa Cruz Do Sul Av.Independencia 2293Santa Cruz Do SulRSBrazil Business School Unisinos UniversityAv.Dr.Nilo Peçanha 160091330-002Porto AlegreBrazil Faculty of Business Administration Lakehead UniversityThunder BayOntarioCanada Autonomous University of Zacatecas Av.Ramon Lopez Velarde Col.CentroZacatecas98000Mexico Department of Computer Science and Artificial Intelligence Andalusian Research Institute in Data Science and Computational Intelligence(DaSCI)University of GranadaGranada 18071Spain York University ON M3J 1P3Canada Department of Information Systems and Cyber Security University of Texas at San AntonioSan AntonioTX78249USA

Big data is a concept that deals with large or complex data sets by using data analysis tools(e.g.,data mining,machine learning)to analyze information extracted from several sources *** data has attracted wide attention from academia,for example,in supporting patients and health professionals by improving the accuracy of decision-making,diagnosis and disease *** research aimed to perform a Bibliometric Performance and Network Analysis(BPNA)supported by a Scoping Review(SR)to depict the strategic themes,thematic evolution structure,main challenges and opportunities related to the concept of big data applied in the healthcare *** this goal in mind,4857 documents from the Web of science covering the period between 2009 to June 2020 were analyzed with the support of SciMAT *** bibliometric performance showed the number of publications and citations over time,scientific productivity and the geographic distribution of publications and research *** strategic diagram yielded 20 clusters and their relative importance in terms of centrality and *** thematic evolution structure presented the most important themes and how it changes over ***,we presented the main challenges and future opportunities of big data in healthcare.

关键词： Big data Healthcare digitalization Bibliometric Strategic intelligence Co-word analysis SciMAT

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：