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International Conference on Computer Supported Cooperative Work in Design

作者： Daya Lages Rodrigues Flávia Maria Santoro Fernanda Araujo Baiao Joanne Manhães Netto Post-graduation Program in Informatics Brazil Federal Service of Data Processing (SERPRO) Rio de Janeiro Brazil

A Knowledge-intensive process (KIP) is characterized as a bag of activities based on knowledge intensive acquisition and manipulation. A KIP differentiates from traditional business processes mainly because of the dynamism or the variability of event flows among the process instances. Thus, traditional business process modeling notations do not adequately represent the broad spectrum of flows that occur in each KIP instance, making them even more challenging to be understood or managed. Some approaches to represent a KIP were defined in the literature, but representing the KIP variability in a cognitively efficient way is still an open issue. This paper presents the graphical notation KIPN-C, which proposes diagrams to represent variability of a KIP relating it to the context of its instances.

关键词： Business

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Evaluation of Game-Based Learning Approaches through Digital Serious Games in Computer Science Higher Education: A Systematic Mapping

Evaluation of Game-Based Learning Approaches through Digital...

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Brazilian Symposium on Games and Digital Entertainment (SBGAMES)

作者： Aliane Loureiro Krassmann Leo Natan Paschoal Andressa Falcade Roseclea Duarte Medina Post-graduation Program on Informatics Federal University of Santa Maria (UFSM) Santa Maria Brazil Computer Science Graduation Cruz Alta's University (UNICRUZ) Cruz Alta Brazil

ISBN: (纸本)9781467388443

This paper conducts a Systematic Mapping in order to outline a current overview of digital serious games applications' evaluations for game-based learning purposes on computer science higher education. The search was performed on informatics' area electronic databases, resulting in 2,174 publications initially found. After sorting through the application of inclusion and exclusion criteria, remained 59. In the final phase, after thorough reading the extracted publications, has come up to 10 papers. The results reveal different practical approaches of digital serious games' applications evaluations that assess its different aspects' influence on students.

关键词： Games Education Computer science Systematics informatics Electronic mail Databases

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Stroke genetics informs drug discovery and risk prediction across ancestries (vol 611, pg 115, 2022)

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NATURE 2022年第7938期612卷 E7-E7页

作者： Mishra, Aniket Malik, Rainer Hachiya, Tsuyoshi Jurgenson, Tuuli Namba, Shinichi Posner, Daniel C. Kamanu, Frederick K. Koido, Masaru Le Grand, Quentin Shi, Mingyang He, Yunye Georgakis, Marios K. Caro, Ilana Krebs, Kristi Liaw, Yi-Ching Vaura, Felix C. Lin, Kuang Winsvold, Bendik Slagsvold Srinivasasainagendra, Vinodh Parodi, Livia Bae, Hee-Joon Chauhan, Ganesh Chong, Michael R. Tomppo, Liisa Akinyemi, Rufus Roshchupkin, Gennady V. Habib, Naomi Jee, Yon Ho Thomassen, Jesper Qvist Abedi, Vida Carcel-Marquez, Jara Nygaard, Marianne Leonard, Hampton L. Yang, Chaojie Yonova-Doing, Ekaterina Knol, Maria J. Lewis, Adam J. Judy, Renae L. Ago, Tetsuro Amouyel, Philippe Armstrong, Nicole D. Bakker, Mark K. Bartz, Traci M. Bennett, David A. Bis, Joshua C. Bordes, Constance Borte, Sigrid Cain, Anael Ridker, Paul M. Cho, Kelly Chen, Zhengming Cruchaga, Carlos Cole, John W. de Jager, Phil L. de Cid, Rafael Endres, Matthias Ferreira, Leslie E. Geerlings, Mirjam I. Gasca, Natalie C. Gudnason, Vilmundur Hata, Jun He, Jing Heath, Alicia K. Ho, Yuk-Lam Havulinna, Aki S. Hopewell, Jemma C. Hyacinth, I. Hyacinth Inouye, Michael Jacob, Mina A. Jeon, Christina E. Jern, Christina Kamouchi, Masahiro Keene, Keith L. Kitazono, Takanari Kittner, Steven J. Konuma, Takahiro Kumar, Amit Lacaze, Paul Launer, Lenore J. Lee, Keon-Joo Lepik, Kaido Li, Jiang Li, Liming Manichaikul, Ani Markus, Hugh S. Marston, Nicholas A. Meitinger, Thomas Mitchell, Braxton D. Montellano, Felipe A. Morisaki, Takayuki Mosley, Thomas H. Nalls, Mike A. Nordestgaard, Borge G. O'Donnell, Martin J. Okada, Yukinori Onland-Moret, N. Charlotte Ovbiagele, Bruce Peters, Annette Psaty, Bruce M. Rich, Stephen S. Rosand, Jonathan Sabatine, Marc S. Sacco, Ralph L. Saleheen, Danish Sandset, Else Charlotte Salomaa, Veikko Sargurupremraj, Muralidharan Sasaki, Makoto Satizabal, Claudia L. Schmidt, Carsten O. Shimizu, Atsushi Smith, Nicholas L. Sloane, Kelly L. Sutoh, Yoichi Sun, Yan V. Tanno, Kozo Tiedt, Steffen Tatlisumak, Turgut Torres-Aguila, Nuria P. Tiwari, Hemant K. Tregouet, Bordeaux Population Health Research Center University of Bordeaux Inserm UMR 1219 Bordeaux France Department of Public Health Bordeaux University Hospital Bordeaux France Department of Neurology Memory Clinic Bordeaux University Hospital Bordeaux France Department of Neurology Institute for Neurodegenerative Diseases CHU de Bordeaux Bordeaux France Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany Center for Genomic Medicine Massachusetts General Hospital Boston MA USA Program in Medical and Population Genetics Broad Institute of Harvard and the Massachusetts Institute of Technology Cambridge MA USA Munich Cluster for Systems Neurology Munich Germany German Center for Neurodegenerative Diseases (DZNE) Munich Germany Iwate Tohoku Medical Megabank Organization Iwate Medical University Iwate Japan Estonian Genome Centre Institute of Genomics University of Tartu Tartu Estonia Institute of Mathematics and Statistics University of Tartu Tartu Estonia Department of Computational Biology University of Lausanne Lausanne Switzerland Swiss Institute of Bioinformatics Lausanne Switzerland University Center for Primary Care and Public Health Lausanne Switzerland Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan Department of Genome Informatics Graduate School of Medicine The University of Tokyo Tokyo Japan Laboratory for Systems Genetics RIKEN Center for Integrative Medical Sciences Yokohama Japan Laboratory of Statistical Immunology Immunology Frontier Research Center (WPI-IFReC) Osaka University Suita Japan Integrated Frontier Research for Medical Science Division Institute for Open and Transdisciplinary Research Initiatives Osaka University Suita Japan Center for Infectious Disease Education and Research (CiDER) Osaka University Suita Japan Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC) VA Boston Healthcare System Boston MA USA TIMI S

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A Genetic Algorithm for the Selection of Features Used in the Prediction of Protein Function

A Genetic Algorithm for the Selection of Features Used in th...

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IEEE Symposium on Bioinformatics and Bioengineering (BIBE)

作者： Larissa Fernandes Leijôto Thiago Assis De Oliveira Rodrigues Luis Enrique Záratey Cristiane Neri Nobre Pontificia Universidade Catolica de Minas Gerais Belo Horizonte MG BR Post-Graduation Program in Inf. Pontificia Universidade Catolica de Minas Gerais Belo Horizonte MG BR Post-Graduation Program in Informatics Pontifical Catholic University of Minas Gerais Brazil

Proteins are macromolecules that have a high molecular weight, and make up, along with water, most of the composition of cells. The functions they perform are extremely important, such as the catalysis of biochemical reactions, cytoskeleton formation, and the transportation and storage of substances. With the completion of genome sequencing, protein discovery has been growing exponentially, and the laboratory methods for determining their functions have not been able to keep up with this growth. Due to this fact, it is necessary to develop methods to aid in this function discovery process. Thus, this work proposes a physical-chemical feature selection methodology calculated by means of the structures that compose the proteins. This stage has the goal of choosing a feature subset from all available features. A feature is considered relevant if it can be used by the machine to create a separation capability between the different protein classes. To select this subset, we proposed the use of a simple genetic algorithm. The results obtained with the proposed methodology were superior to those found in the literature, reaching a precision of 71% and a sensitivity of 68%.

关键词： Proteins Support vector machines Amino acids Genetic algorithms Sensitivity Feature extraction Databases

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Computational Simulation of High-concentration Erbium Media for Lasers Development

Computational Simulation of High-concentration Erbium Media ...

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The 2013 2nd International Symposium on Manufacturing Systems Engineering(ISMSE 2013)

作者： Nélito Bernardes Pereira Junior André Felipe Henriques Librantz Wonder Alexandre Luz Alves Alessandro Melo Deana Industrial Engineering Post Graduation Program Nove de Julho University (UNINOVE) Department of Informatics Nove de Julho University Biophotonics Post Graduation Program Nove de Julho University (UNINOVE)

Different laser designs may require high-concentration erbium lasersThe laser efficiency can be measured by the small signal gain(SSG) of the laser mediaIn this paper an investigation of the SSG for a Er:YLF with 40 mol % of erbium concentration were carried out by means of computational simulation considering several pumping rates and different pulse durationResults showed that the maximum SSG values for 40% Er concentration are reached for lower pulse durations and high pumping ratesIn addition, results suggest that the performance of such lasers can be significantly enhanced by the adjustment of pulse duration and the interval between two consecutive pulses.

关键词： Erbium Er YLF laser HIGH-concentration erbium-doped Computational simulation

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Proposal and development of the Web services input validation model

Proposal and development of the Web services input validatio...

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IEEE Symposium on Network Operations and Management

作者： Rafael Bosse Brinhosa Carla Merkle Westphall Carlos Becker Westphall Post Graduation Program in Computer Science (PPGCC) Department of Informatics and Statistics (INE) Federal University of Santa Catarina Florianopolis Brazil

The SOA architecture primarily based on Web services is experiencing a steady adoption, although its growth was lower than expected when it was launched, mainly because of security related concerns. Web services inherited many well-known security problems of Web applications and brought new ones. Major data breaches today are consequences of bad input validation at the application level. This paper presents a way to implement an input validation model for Web services which can be used to prevent cross-site scripting and SQL injection through the use of predefined models which specify valid inputs. The proposed WSIVM (Web Services Input Validation Model) consists of an XML schema, an XML specification, and a module for performing input validation according to the schema. A case study showing the effectiveness and performance of this mechanism is also presented.

关键词： Security Service oriented architecture XML Simple object access protocol Standards

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Semi-automatic Follow-Up of Graduates

Semi-automatic Follow-Up of Graduates

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Computer Science Society (SCCC) International Conference Chilean FLAGGED

作者： Diego Fialho Rodrigues Alcione de Paiva Oliveira Jugurta Lisboa Filho Alexandra Moreira Department of Informatics Federal University of Viçosa Vicosa Brazil Post-Graduation Program in Linguistics Federal University of Juiz de Fora Juiz de Fora Brazil

Many institutions needs to gather and store information about people connected to their activities. An automated system to accomplish this task needs to overcome several challenges: collect information on textual and semi-structured textual databases, execute textual inferences, identify individuals, integrate distributed information, etc. Multiagent systems may help solve these problems gradually and scalably. This article describes the design and implementation of a Multiagent system that collects public information about graduates gathered from a mailing list.

关键词： Ontologies Semantics Companies Multi-agent systems Educational institutions Monitoring Databases

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An Estimate of the Cost of Hepatitis C Treatment for the Brazilian Health System

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Value in Health Regional Issues 2012年第2期1卷 129-135页

作者： Blatt, Carine Raquel Bernardo, Noemia Liege Maria da Cunha Rosa, Junior Andre Bagatini, Fabiola Alexandre, Rodrigo Fernandes Balbinotto Neto, Giacomo Siebert, Uwe Rocha Farias, Mareni Pharmacy Post Graduation Program University of Santa Catarina State UFSC Florianópolis SC Brazil Department of Public Health and Health Technology Assessment UMIT - University for Health Sciences Medical Informatics and Technology Hall in Tirol Austria University of Santa Catarina South UNISUL Tubarão SC Brazil Ministry of Health Brasília DF Brazil University of Rio Grande do Sul State Porto Alegre RS Brazil ONCOTYROL - Center for Personalized Cancer Medicine Innsbruck Austria Department of Health Policy and Management Harvard School of Public Health Boston MA United States Institute for Technology Assessment and Department of Radiology Massachusetts General Hospital Harvard Medical School Boston MA United States

Objectives: Hepatitis C therapy in Brazil is expensive due to the cost of antiviral drugs and demands on medical resources. The objective of this study was to estimate the direct costs per patient of chronic hepatitis C therapy in a Brazilian setting. Method: A microcosting study from a public health system perspective. The costs included were those of antiviral drugs, secondary medicines, diagnostic tests, visits to physicians and other professionals, hospitalization, nurse, and pharmaceutical care. All costs were priced in 2010. The values were converted to US $ (2010). Results: The total direct cost of hepatitis C treatment per patient with interferon alpha (IFN) plus ribavirin (RBV) was US $982.25, with peginterferon alpha (PEG) 2a 180 μg plus RBV was US $10,658.08, and with PEG 2b 120 μg plus RBV was US $12,597.63, taking into account entire treatment according to Brazilian guidelines and assuming that all patients completed full treatment. The antiviral drugs are the most expensive element of the cost of treatment, totaling more than 40% of the medical costs of IFN plus RBV therapy and more than 88% of PEG plus RBV therapy. Calculating an average of 10,000 treatments per year, the total direct cost is US $90,346,772.39. According to the Ministry of Health, 90% of the annual total cost of hepatitis C treatment is accounted for by antiviral drugs. Conclusions: In Brazil, antiviral drugs are the most expensive component of hepatitis C treatment. The cost of follow-up and support to patients is minimal compared with the cost of antiviral drugs. © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).

关键词： Direct cost Hepatitis C Hepatitis C treatment Interferon

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A Parametric QoE Video Quality Estimator for Wireless Networks

A Parametric QoE Video Quality Estimator for Wireless Networ...

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Institute of Electrical and Electronics Engineers Globecom Workshops

作者： E. Cerqueira Augusto Neto M. Curado A. Riker R. Immich H. Barros E. Aguiar A. Abelem Federal University of Para (UFPA) Federal University of Ceara Department of Informatics Engineering (DETI) Fortaleza-CE Institute of Telecommunications Aveiro University of Coimbra Department of Informatics Engineering (DEI) Federal University of Rio Grande do Norte Post Graduation Program in Computer Systems (PPgSC)

ISBN: (纸本)9781467349420

The development of real-time quality estimator schemes for emerging Internet videos with different content types remains a significant challenge and is crucial for the success of wireless multimedia systems. However, currently in-service assessment schemes fail in capturing subjective aspects of multimedia content related to the user perception. Therefore, this paper proposes an on-the-fly parametric video quality estimator approach (called MultiQoE) for real-time video streaming applications. Experiments in a Wireless Mesh Network (WMN) scenario were carried out to show the accuracy, benefit, and impact of MultiQoE compared to widely used Quality of Experience (QoE) subjective, objective and parametric methods.

关键词： Quality of Experience Video Streaming Wireless Mesh Networks Service Assessment

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Porantim-opt: Optimizing the combined selection of model-based testing techniques

Porantim-opt: Optimizing the combined selection of model-bas...

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Workshop on Requirements and Validation, Verification, and Testing

作者： Neto, Arilo Claudio Dias De Freitas Rodrigues, Rosiane Travassos, Guilherme Horta Post-graduation Program In Informatics Computer Science Department Federal University of Amazonas Manaus AM Brazil Systems Engineering and Computer Science Program COPPE Federal University of Rio De Janeiro Rio De Janeiro RJ Brazil

ISBN: (纸本)9780769543451

The combination of testing techniques is considered an effective strategy to evaluate a software product. However, the selection of which techniques to combine in a software project has been an interesting challenge in the Software Engineering field. This paper presents a proposal extending an approach developed to support the combined selection of model-based testing (MBT) techniques, named Porantim, applying Multiobjective Combinatorial Optimization strategy by determining the smallest dominating set in a bipartite and weighted graph. Thus, a local search strategy algorithm is proposed generating solutions aiming at maximizing the coverage of software project characteristics and skills required by the testing team to use the techniques and minimizing the eventual effort to construct models used for test cases generation. A preliminary evaluation analyzes this new approach when compared to the Porantim's original version, and the results indicate improvements in the MBT techniques selection. © 2011 IEEE.

关键词： Software testing

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