检索结果-内蒙古大学图书馆

Current status of the preclinical evaluation of alternating electric fields as a form of cancer therapy

Bioelectrochemistry 2023年 149卷 108287页

作者： Pohling, Christoph Nguyen, Ha Chang, Edwin Schubert, Keith E. Nie, Ying Bashkirov, Vladimir Yamamoto, Vicky Zeng, Yuping Stupp, Roger Schulte, Reinhard W. Patel, Chirag B. Division of Biomedical Engineering Sciences Loma Linda University School of Medicine Loma LindaCA92350 United States Department of Electrical and Computer Engineering Baylor University WacoTX76798 United States Molecular Imaging Program at Stanford Department of Radiology Stanford University School of Medicine StanfordCA94305 United States Department of Neurosurgery Loma Linda University School of Medicine Loma LindaCA92350 United States Norris Comprehensive Cancer Center University of Southern California Keck School of Medicine Los AngelesCA90033 United States Department of Electrical and Computer Engineering University of Delaware NewarkDE19716 United States Department of Neurosurgery Department of Neurology Division of Neuro-OncologyDepartment of Medicine Division of Hematology/Oncology Northwestern University Feinberg School of Medicine ChicagoIL60611 United States Department of Neuro-Oncology The University of Texas MD Anderson Cancer Center HoustonTX77030 United States Neuroscience Graduate Program The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences HoustonTX77030 United States Cancer Biology Graduate Program The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences HoustonTX77030 United States

Exposing cancer cells to alternating electric fields of 100-300 kHz frequency and 1-4 V/cm strength has been shown to significantly reduce cancer growth in cell culture and in human patients. This form of anti-cancer therapy is more commonly referred to as tumor treating fields (TTFields), a novel treatment modality that has been approved by the U.S. Food and Drug Administration for use in patients with glioblastoma and malignant pleural mesothelioma. Pivotal trials in other solid organ cancer trials are underway. In regards to overall survival, TTFields alone is comparable to chemotherapy alone in recurrent glioblastoma. However, when combined with adjuvant chemotherapy, TTFields prolong median survival by 4.9 months in newly-diagnosed glioblastoma. TTFields hold promise as a therapeutic approach to numerous solid organ cancers. This review summarizes the current status of TTFields research at the preclinical level, highlighting recent aspects of a relatively complex working hypothesis. In addition, we point out the gaps between limited preclinical in vivo studies and the available clinical data. To date, no customized system for TTFields delivery in rodent models of glioblastoma has been presented. We aim to motivate the expansion of TTFields preclinical research and facilitate the availability of suitable hardware, to ultimately improve outcomes in patients with cancer. © 2022 The Authors

关键词： Tumors

来源：评论

学校读者我要写书评

暂无评论

Deep Learning with Greedy Layer-Wise Compound Scaling for Temperature and Humidity Prediction in Solar Dryer Dome

SSRN

引用

SSRN 2022年

作者： Cenggoro, Tjeng Wawan Elwirehardja, Gregorius Natanael Dominic, Nicholas Setiawan, Karli Eka Rahutomo, Reza Djuana, Endang Gunawan, Fergyanto E. Budiman, Arief S. Romeli, Sugiarto Pardamean, Bens Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program Master of Computer Science Program Bina Nusantara University Jakarta11480 Indonesia Information Systems Department School of Information Systems Bina Nusantara University Jakarta11480 Indonesia Electrical Engineering Department Faculty of Industrial Technology Universitas Trisakti Jakarta11440 Indonesia Industrial Engineering Department BINUS Graduate Program Master of Industrial Engineering Bina Nusantara University Jakarta11480 Indonesia Department of Manufacturing and Mechanical Engineering and Technology Oregon Institute of Technology Klamath FallsOR97601 United States PT. Impack Pratama Industri Jakarta Indonesia

Drying has been an eco-friendly and cost-efficient method to reduce post-harvest losses of agricultural crops. In various countries, the technique has been widely utilized in the form of Solar Dryer Dome (SDD) buildings. Accurate indoor microclimate forecasting is very important to implement smart control systems in SDDs that can maintain the ideal conditions, as the availability of solar energy is limited only at daytimes and the temperature may drop significantly during nighttimes in remote areas. The microclimate variables that play an important role in maintaining ideal environmental conditions include temperature and relative humidity. © 2022, The Authors. All rights reserved.

关键词： Forecasting

来源：评论

学校读者我要写书评

暂无评论

Biophysics of amplitude-modulated giga-hertz electromagnetic waves stimulation

Biophysics of amplitude-modulated giga-hertz electromagnetic...

引用

Asilomar Conference on Signals, Systems & computers

作者： Fatima Ahsan Aravind C. Govindaraju Robert M. Raphael Taiyun Chi Sameer A. Sheth Wayne Goodman Behnaam Aazhang Department of Electrical and Computer Engineering Rice University Houston TX USA Applied Physics Graduate Program Smalley-Curly Institute Rice University Houston TX Department of Bioengineering Rice University Houston TX USA Department of Neurosurgery Baylor College of Medicine Houston TX USA Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine Houston TX USA

This paper presents the biophysical modeling for neuronal stimulation caused by amplitude-modulated giga-hertz (GHz) electromagnetic (EM) waves. We model a 1D cable equation for electrical signal propagation in a vestibular ganglion neuronal fiber and use Hodgkin-Huxley formalism to model voltage-dependent channel conductances. We find out that for a given stimulation signal strength, the GHz waveform amplitude-modulated at a low frequency of Δf causes neuronal firing with the frequency of Δf whereas the continuous wave GHz did not elicit any neuronal firing. Moreover, the voltage-dependent channel gating dynamics of the Δf amplitude-modulated GHz stimulation matches that of a simple low frequency stimulation at Δf. Additionally, we find that the modulation depth controls the firing rate of the neurons. The significance of this property is that the amplitude modulation caused by the interference of two similar high frequency signals could be leveraged to focally excite neurons at depth without stimulating overlying cortical regions. These theoretical predictions based on the Hodgkin-Huxley model can later be tested experimentally.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Quantifying Efficiency of Remote Excitation for Surface Enhanced Raman Spectroscopy in Molecular Junctions

arXiv

引用

arXiv 2023年

作者： Liao, Shusen Zhu, Yunxuan Ye, Qian Sanders, Stephen Yang, Jiawei Alabastri, Alessandro Natelson, Douglas Applied Physics Graduate Program Smalley-Curl Institute Rice University HoustonTX77005 United States Department of Physics and Astronomy Rice University HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Department of Materials Science and NanoEngineering Rice University HoustonTX77005 United States

Surface-enhanced Raman spectroscopy (SERS) is enabled by local surface plasmon resonances (LSPRs) in metallic nanogaps. When SERS is excited by direct illumination of the nanogap, the background heating of lattice and electrons can prevent further manipulation of the molecules. To overcome this issue, we report SERS in electromigrated gold molecular junctions excited remotely: surface plasmon polaritons (SPPs) are excited at nearby gratings, propagate to the junction, and couple to the local nanogap plasmon modes. Like direct excitation, remote excitation of the nanogap can generate both SERS emission and an open-circuit photovoltage (OCPV). We compare SERS intensity and OCPV in both direct and remote illumination configurations. SERS spectra obtained by remote excitation are much more stable than those obtained through direct excitation when photon count rates are comparable. By statistical analysis of 33 devices, coupling efficiency of remote excitation is calculated to be around 10%, consistent with the simulated energy flow. Copyright © 2023, The Authors. All rights reserved.

关键词： Raman spectroscopy

来源：评论

学校读者我要写书评

暂无评论

Distributionally Robust Chance-Constrained Optimal Transmission Switching for Renewable Integration

arXiv

引用

arXiv 2021年

作者： Zhou, Yuqi Zhu, Hao Hanasusanto, Grani A. The Department of Electrical & Computer Engineering The University of Texas at Austin AustinTX78712 United States The Graduate Program in Operations Research & Industrial Engineering The University of Texas at Austin AustinTX78712 United States

Increasing integration of renewable generation poses significant challenges to ensure robustness guarantees in real-time energy system decision-making. This work aims to develop a robust optimal transmission switching (OTS) framework that can effectively relieve grid congestion and mitigate renewable curtailment. We formulate a two-stage distributionally robust chance-constrained (DRCC) problem that assures limited constraint violations for any uncertainty distribution within an ambiguity set. Here, the second-stage recourse variables are represented as linear functions of uncertainty, yielding an equivalent reformulation involving linear constraints only. We utilize moment-based (mean-mean absolute deviation) and distance-based (∞-Wasserstein distance) ambiguity sets that lead to scalable mixed-integer linear program (MILP) formulations. Numerical experiments on the IEEE 14-bus and 118-bus systems have demonstrated the performance improvements of the proposed DRCC-OTS approaches in terms of guaranteed constraint violations and reduced renewable curtailment. In particular, the computational efficiency of the moment-based MILP approach, which is scenario-free with fixed problem dimensions, has been confirmed, making it suitable for real-time grid operations. Copyright © 2021, The Authors. All rights reserved.

关键词： Computational efficiency

来源：评论

学校读者我要写书评

暂无评论

Electromagnetic textile absorber applied to 4G and 5G bands

引用

Scientific reports 2025年第1期15卷 18768页

作者： Paulo H B Carvalho Ewaldo E C Santana Allan K D Barros Filho Paulo F Silva Júnior Keyll C R Martins Talita C Azevedo Waldemir P Martins Mauro A Medeiros Rubens S Gonçalves Lourival M Sousa Filho Gricirene S Correia Gabrielle M Fernandes Talita C Pinheiro Brenda A S Rodrigues Carlos A M Cruz Graduate Program in Electrical Engineering Federal University of Maranhão (UFMA) São Luís MA Brazil. phenrique@ifma.edu.br. Graduate Program in Electrical Engineering Federal University of Maranhão (UFMA) São Luís MA Brazil. Graduate Program in Computer and Systems Engineering Maranhão State University (UEMA) São Luís MA Brazil. Graduate Program in Mechanical Engineering Federal Institute of Maranhão (IFMA) São Luís MA Brazil. Department of Electrical Engineering Federal Institute of Paraíba (IFPB) João Pessoa PB Brazil. Graduate Program in Electrical Engineering Federal University of Amazonas (UFAM) Manaus AM Brazil. Department of Electronics and Computation Federal University of Amazonas (UFAM) Manaus AM Brazil.

Absorber materials are developed to reduce electromagnetic radiation and ensure the compatibility of the operation of electronic equipment in environments subject to interference. This work presents the development of a low-cost textile electromagnetic absorber for 4G and 5G technologies, operating at frequencies of 2.5 GHz and 3.5 GHz. The proposed electromagnetic absorber utilizes a 1 mm-thick Denim substrate, with a graphite composite used in the agricultural and commercial polyvinyl acetate glue industry, with the relationship of 25 wt%. The measurements were carried out in a Vector Network Analyzer, model E5071C Agilent Technologies, with the characterization of the Denim substrate, the glue, and the identification of the best parameters for the construction of the absorber. In the project, three low-cost textile absorbers prototypes were fabricated, with G1 = 0.25 mm, G2 = 0.35 mm, and G3 = 0.5 mm of thickness layers of the composite deposited on a Denim fabric. The results indicate that the absorber prototypes G2 presents great results in the frequency range of 4G and 5G band, with a maximum absorption of 26.6 dB in 3.94 GHz, with a structure 98.83% thinner than the commercial absorber LF-75. The variation in absorption performance may be attributed to the different mechanisms by which the absorbers operate: the commercial absorber LF-75 primarily interacts with the magnetic field, whereas the textile prototype predominantly affects the electric field.

关键词： 4G and 5G bands Electromagnetic Low-cost Textile absorber

来源：评论

学校读者我要写书评

暂无评论

Measurement of Water Diffusion Coefficient in Cross-Linked Gelatins Using the Terahertz Time-Domain Spectroscopy Technique

Measurement of Water Diffusion Coefficient in Cross-Linked G...

引用

Conference on Lasers and Electro-Optics (CLEO)

作者： D. Walden D. Chakraborty J. Cheng A. Straksys A. Stirke W. CMA Melo A. Jukna I. Komissarov Roman Sobolewski Department of Physics and Astronomy University of Rochester Rochester New York USA Laboratory for Laser Energetics University of Rochester Rochester New York USA Materials Science Graduate Program University of Rochester Rochester New York USA State Research Institute Center for Physical Sciences & Technology Vilnius Lithuania Department of Physics Vilnius Gediminas Technical University Vilnius Lithuania Department of Electrical and Computer Engineering University of Rochester Rochester New York USA

A novel method has been developed to evaluate the water diffusion dynamics in gelatin-based gels, based on transient terahertz time-domain spectroscopy measurements. Such gels are widely used models for human skin.

ISBN: (纸本)9798350369311

关键词： Spectroscopy Measurement by laser beam Lasers and electrooptics Laser modes Skin Time-domain analysis Transient analysis Electro-optical waveguides

来源：评论

学校读者我要写书评

暂无评论

Protomon: A Multimode Qubit in the Fluxonium Molecule

arXiv

引用

arXiv 2024年

作者： Kumar, Shashwat You, Xinyuan Croot, Xanthe Zhao, Tianpu Chen, Danyang Sussman, Sara Premkumar, Anjali Bryon, Jacob Koch, Jens Houck, Andrew A. Department of Electrical and Computer Engineering Princeton University PrincetonNJ08544 United States Northwestern–Fermilab Center for Applied Physics and Superconducting Technologies Northwestern University EvanstonIL60208 United States Graduate Program in Applied Physics Northwestern University EvanstonIL60208 United States Department of Physics Princeton University PrincetonNJ08544 United States Department of Physics and Astronomy Northwestern University EvanstonIL60208 United States

Qubits that are intrinsically insensitive to depolarization and dephasing errors promise to significantly reduce the overhead of fault-tolerant quantum computing. At their optimal operating points, the logical states of these qubits exhibit both exponentially suppressed matrix elements and sweet spots in energy dispersion, rendering the qubits immune to depolarization and dephasing, respectively. We introduce a multimode qubit, the protomon, encoded in a fluxonium molecule circuit. Compared to the closely related 0–π qubit, the protomon offers several advantages in theory: resilience to circuit parameter disorder, minimal dephasing from intrinsic harmonic modes, and no dependence on static offset charge. As a proof of concept, we realize four protomon qubits. By tuning the qubits to various operating points identified with calibrated two-tone spectroscopy, we measure depolarization times ranging from 64 to 73 µs and dephasing times between 0.2 to 0.5 µs for one selected qubit. The discrepancy between the relatively short measured coherence times and theoretical predictions is not fully understood. This calls for future studies investigating the limiting noise factors, informing the direction for improving coherence times of the protomon qubit. © 2024, CC BY.

关键词： Qubits

来源：评论

学校读者我要写书评

暂无评论

Machine learning and deep learning based psoriasis recognition system: evaluation, management, prognosis—where we are and the way to the future

引用

Artificial Intelligence Review 2025年第9期58卷

作者： Shehzadi, Nimra Rehman, Arshia Naz, Saeeda Rehman, Saba Khalifa, Fahmi Department of Computer Science Govt Girls Post Graduate College No.1 Abbottabad Pakistan Department of Computer Science Comsats University of Islamabad Abbottabad Pakistan Department of Psychology COMSATS University of Islamabad Abbottabad Pakistan Electrical and Computer Engineering Department School of Engineering Morgan State University BaltimoreMD21251 United States

Psoriasis, a chronic inflammatory skin disease, poses significant diagnostic challenges due to its heterogeneous clinical manifestations and overlap with other dermatological conditions. The inconsistencies in diagnostic standards and variability in disease presentation further exacerbate the controversy surrounding the diagnosis of psoriasis. Recent advances in artificial intelligence (AI), particularly deep learning (DL) techniques such as convolutional neural networks (CNNs) and transformers, have shown promising results in improving recognition of psoriasis. This comprehensive review aims to provide an in-depth examination of the current state of AI applications in the diagnosis of psoriasis, highlighting the strengths and limitations of existing approaches. We evaluate the performance of various AI models on publicly available datasets, including the Psoriasis Image Dataset (PID) and the International Skin Imaging Collaboration (ISIC) dataset, and compare their accuracy, sensitivity, and specificity with traditional diagnostic methods. Furthermore, we discuss the challenges and future directions of AI-powered psoriasis diagnosis, including the need for large, diverse datasets, addressing data quality and generalization issues, and developing explainable AI models. Our review highlights the potential of AI to revolutionize the diagnosis and management of psoriasis and provides a pathway for future research in this field. © The Author(s) 2025.

关键词： Convolutional neural networks

来源：评论

学校读者我要写书评

暂无评论

Terahertz spin dynamics in rare-earth orthoferrites

引用

Photonics Insights 2022年第2期1卷 1-56页

作者： Xinwei Li Dasom Kim Yincheng Liu Junichiro Kono Department of Physics California Institute of TechnologyPasadenaUSA Department of Electrical and Computer Engineering Rice UniversityHoustonUSA Applied Physics Graduate Program Smalley-Curl InstituteRice UniversityHoustonUSA Department of Physics and Astronomy Rice UniversityHoustonUSA Department of Materials Science and NanoEngineering Rice UniversityHoustonUSA

Recent interest in developing fast spintronic devices and laser-controllable magnetic solids has sparked tremendous experimental and theoretical efforts to understand and manipulate ultrafast dynamics in *** of spin dynamics in the terahertz(THz)frequency range are particularly important for elucidating microscopic pathways toward novel device ***,we review THz phenomena related to spin dynamics in rare-earth orthoferrites,a class of materials promising for antiferromagnetic *** expand this topic into a description of four key elements.(1)We start by describing THz spectroscopy of spin excitations for probing magnetic phase transitions in thermal *** acoustic magnons are useful indicators of spin reorientation transitions,electromagnons that arise from dynamic magnetoelectric couplings serve as a signature of inversion-symmetry-breaking phases at low temperatures.(2)We then review the strong laser driving scenario,where the system is excited far from equilibrium and thereby subject to modifications to the free-energy *** pathways for ultrafast laser manipulation of magnetic order are discussed.(3)Furthermore,we review a variety of protocols to manipulate coherent THz magnons in time and space,which are useful capabilities for antiferromagnetic spintronic applications.(4)Finally,new insights into the connection between dynamic magnetic coupling in condensed matter and the Dicke superradiant phase transition in quantum optics are *** presenting a review on an array of THz spin phenomena occurring in a single class of materials,we hope to trigger interdisciplinary efforts that actively seek connections between subfields of spintronics,which will facilitate the invention of new protocols of active spin control and quantum phase engineering.

关键词： terahertz spin dynamics magnetism orthoferrite ultrafast spectroscopy magneto-optics

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：