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Micro-electrode array (MEA) electrophysiological signal analysis by descriptive stochastic tests of the probability density structure

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Research on Biomedical engineering 2025年第2期41卷 1-13页

作者： Faria, Vinícius Naves Rezende Ramos, Marina Abadia Martinoia, Sérgio Destro-Filho, João-Batista Postgraduate Program in Electrical Engineering Universidade Federal de MG Uberlândia Brazil Postgraduate Program in Biomedical Sciences Universidade Federal de MG Uberlândia Brazil Division of Informatics Bioengineering Robotics and System Engineering Università Degli Studi Di Genova Genova Italy

Purpose: The primary objective of this study is to present, analyze, and quantitatively characterize the electrical signals obtained from neuronal cultures coupled to micro-electrode arrays (MEAs). Special attention is given to the temporal evolution of electrical activity across distinct geometric regions of the MEA devices. Methods: The proposed methodology involves signal acquisition, classical analysis based on spike and burst detection, and, critically, the characterization of the probability density structure of the signals. This is achieved through the quantification of Gaussianity—expressed as the percentage of segments non-Gaussian (PSNG)—and stationarity— expressed as the percentage of segments non-stationary (PSNE). Results: Initial analyses showed that first-order power spectral density quantifiers lacked the statistical robustness required to effectively describe the complex components of MEA signals. In contrast, PSNG and PSNE demonstrated strong potential in capturing the different stages of neuronal culture development. Cluster analysis further supported the discriminative capacity of these quantifiers. Conclusion: The phase corresponding to decreased neuronal activity and onset of cell death—a biologically critical stage—exhibited the strongest correlation among the studied variables. These results suggest a discernible biological organization and highlight the relevance of PSNG and PSNE as promising tools for assessing neuronal culture dynamics. © The Author(s), under exclusive licence to The Brazilian Society of Biomedical engineering 2025.

关键词： Cell death

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The sensitivity analysis using adjoint method in numerical modeling of electric potential distribution of the transmission lines

The sensitivity analysis using adjoint method in numerical m...

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作者： Paganotti, André Luiz Saldanha, Rodney Resende Lisboa, Adriano Chaves Afonso, Márcio Matias Duane, Bell Abrão Marques Electrical Engineering Postgraduate Program UFSJ-CEFET-MG Minas Gerais Brazil Graduate Program in Electrical Engineering UFMG Minas Gerais Brazil

This paper proposes a new methodology for sensitivity analysis evaluation, fast and with high precision of the electric potential distribution near the transmission lines (TL's). The TL is modeled by the finite element method and the sensitivity of the cable positions is obtained using the adjoint method. The sensitivity of the objective function during the optimization process by using methods based on gradient information is obtained by using the adjoint method. The exact sensitivity obtained by the adjoint method concerning the numeric model of the TL's results in new geometries of the bundles conductors with high surge impedance loading. These geometries are not possible to get using analytic models. The sensitivities of a large number of conductors by phase are obtained with high precision and very low computational cost using adjoint sensitivities, which are independent of the number of design variables. The central finite difference method is used to calculate the sensitivities and to validate the adjoint method. With this methodology, the FEM model of the TL can be used during the optimization process without compromising the required computational processing time. © 2024 John Wiley & Sons Ltd.

关键词： Electric lines

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Analytical Evaluation of Natural Frequencies in Hollow-Core Slabs: A Practical Methodology for Civil engineering Applications

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Iranian Journal of Science and Technology - Transactions of Civil engineering 2024年第2期49卷 1979-1991页

作者： Zenatti, Carlos N. Silveira, Guilherme S. Gidrão, Gustavo M. S. Novak, Paulo Rogério Bosse, Rúbia Mara Silvestro, Laura Marcos, Lara K. Civil Engineering Postgraduate Program PPGEC Federal University of Technology - Paraná (UTFPR) Paraná Pato Branco Brazil

This study presents an analytical methodology for predicting the natural frequencies of hollow-core slab panels, addressing a significant research and application need in structural engineering. The study suggests a numerical–experimental calibration utilizing the Finite Element Method (FEM) via ANSYS software to assess the modal response of hollow-core slabs validated according to literature study. Through the development of Irvine’s equation, this research proposes a simplified methodology for determining the natural frequency of slabs. The slabs were modeled as simply supported beams, and Irvine’s equations have been applied to simplify several degrees of freedom structure (SDOF) and determine the natural frequencies for various spans. The validation of the numerical–experimental model indicates a maximum error of 8.32% in the third vibration mode, demonstrating the accuracy and practicality of the proposed analytical method. This approach could be useful in determining the vibration serviceability presented in Brazilian Standard Procedure for the Design of Concrete Structures. It can help engineers and manufacturers to estimate structural compliance and vibration serviceability. © The Author(s), under exclusive licence to Shiraz University 2024.

关键词： Analytical method Hollow-core slab Modal analysis Natural frequency

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The influence of plastic waste on the properties of lime-based mortars

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Frontiers of Structural and Civil engineering 2025年第3期19卷 477-487页

作者： Vasiliki PACHTA Angeliki-Christina VEDINOGLOU Sofia FLEVARAKI Laboratory of Building Materials School of Civil EngineeringAristotle University of ThessalonikiThessaloniki 54124Greece Interdepartmental Program of Postgraduate Studies‘Protection Conservation and Restoration of Cultural Monuments’ Aristotle University of ThessalonikiThessaloniki 54124Greece

The increasing consumption of plastics, and the threat of environmental impact of their disposal, renders the management of their waste of interest. In the present study, an effort has been made to investigate the influence of waste polyvinyl chloride (PVC) and polypropylene (PP) of various origin in lime-based mortars, applied in the restoration of traditional structures. Nine mortar compositions (based on lime and natural pozzolan) were designed, manufactured and tested, in which natural aggregates were partially substituted by waste plastics (in proportions of 12.5% and 25% v/v of aggregates). According to the research results, shrinkage deformations were reduced in the short term in all modified compositions, porosity showed slight changes, while apparent specific gravity and capillary absorption index were decreased. Mechanical properties were enhanced in the case of the PVC and the lower PP flakes addition (12.5% v/v), while compressive strength was reduced around 5%–25% in the higher proportion (25% v/v). Generally, it could be asserted that the 12.5% v/v proportion of waste plastics offered benefit, and in particular PVC addition was beneficial in terms of physico-mechanical properties, rendering the exploitation of plastic waste in lime-based systems feasible.

关键词： plastic waste lime mortars pozzolan polypropylene polyvinyl chloride

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Case study of condominium management in Brazil: survey of 30 years of maintenance and renovation costs of a 1982 multifamily residential building

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Journal of Building Pathology and Rehabilitation 2024年第2期9卷 1-14页

作者： Machado, Adryelle Dias Novaes Siqueira, Anna Luiza Dias de Castro, Júlia Assumpção de Carvalho, Aldo Ribeiro Pita, Romário Parreira Mendes, Julia Castro Postgraduate Program in Civil Engineering Federal University of Ouro Preto Minas Gerais Ouro Preto CEP 35402-163 Brazil Postgraduate Program in Civil Engineering Federal University of Juiz de Fora Minas Gerais Juiz de Fora CEP 36036-900 Brazil

This study carries out a case study of maintenance costs in a multi-family residential building built in 1982 in a mid-size city in Brazil. The condominium's monthly cost reports (maintenance fees) were analyzed for 30 years, between 1991 and 2021. This long period of analysis unprecedented in the literature. Expenses were classified by system and type of maintenance (preventive, corrective or modernization renovation). We identified that maintenance on elevator systems and gardens summed up the highest costs throughout the period, while envelope conservation, sewage systems and water tanks presented the lowest costs. Disregarding the extreme years and correcting for inflation, the average expenditure on maintenance in the last 5 years (2017–2021) was 175% higher than the first 5 years analyzed (1991–1995), with the condominium fee being 43.6% higher. If the (predictable) maintenance expenses over the years were considered from the beginning of the building's operation, current families could be paying around 15% less in condominium fees. In conclusion, for an efficient maintenance management system, construction professional must focus on maintenance from the project design stage, provide a financial reserve for future upkeeping and renovation from the beginning of occupation, and prepare a robust user manual. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.

关键词： Building maintenance Case study Maintenance costs Use and operation manual

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The main contributions of digitalisation to servitisation

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International Journal of Manufacturing Technology and Management 2025年第3-5期39卷 358-389页

作者： Fronteli, Márcio Henrique Paladini, Edson Pacheco Gaspar Santa Catarina89111-009 Brazil Postgraduate Program in Production Engineering Federal University of Santa Catarina Carvoeira Florianópolis Santa Catarina88040-535 Brazil

Digital servitisation has aroused the interest of many researchers and managers. IoT, big data, and cloud computing are the most prominent technologies. This study sought to investigate the impact of other digital technologies (DTechs) on servitisation. This research is based on an exploratory-qualitative approach covering 146 published articles selected from the Scopus and Web of Science databases. We grouped the digital technologies that impacted servitisation positively. Our results were synthesised into four categories. These procedures allowed for building a framework that shows the contribution potential of digitisation as a success factor of servitisation, as well as competitive opportunities based on the combination of DTs. Digitisation is confirmed as the main driver for the development of digital-servitisation based business models. Our results aim to contribute to the industry in terms of establishing innovation strategies for business models. Copyright © 2025 Inderscience Enterprises Ltd.

关键词： Dynamic random access storage

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Degradation of antibiotic sulphamethoxazole by application of modified photo-Fenton processes: kinetics, degradation pathways and toxicity

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International Journal of Environmental Studies 2024年第2期81卷 693-723页

作者： de Oliveira Cardoso Nascimento, Camila Palácio, Soraya Moreno Veit, Márcia Teresinha Borba, Fernando Henrique Zorzo, Camila Fernanda Amado, Daieni Vieira Department of Chemical Engineering Western Paraná State University-UNIOESTE Toledo Brazil Postgraduate Program of Environment and Sustainable Technologies Federal University of Fronteira Sul Cerro Largo Brazil

Degradation of antibiotic sulphamethoxazole (SMX) was studied by applying modified photo-Fenton reactions (MPF) with the novel choice of using sodium tripolyphosphate (STP) and sodium hexametaphosphate (SHP) complexing agents. STP and SHP have a strong ability as complexing agents because they can sequester and complex with different ions. Process optimisation was performed using Doehlert design at pH = 6. This study presented higher performance for MPF using STP and SHP complexing agents than conventional photo-Fenton and H2O2 + UV process. The best yields were associated with the formation of a smaller number of intermediates with high degradation efficiency and low oxidative stress, environment-friendly and promising processes. © 2024 Informa UK Limited, trading as Taylor & Francis Group.

关键词： Antibiotics

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Harnessing 3D seismic data for mapping natural CO2distribution: Paving the way for future CCS/CCUS implementation in the Lower Talang Akar Formation, Jabung Block, South Sumatra Basin

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Leading Edge 2024年第8期43卷 538-543页

作者： Alamsyah, Muhammad Noor Sukmono, Sigit Winardhi, Sonny Wicaksono Fitrianto, Teguh Sulistyanto, Arno Germanndaputra PetroChina International Jabung Ltd Jakarta Indonesia Bandung Institute of Technology Geophysical Engineering Postgraduate Program West Java Indonesia Bandung Institute of Technology Engineering and Exploration Seismology Research Group West Java Indonesia

Hydrocarbon reservoirs saturated with CO2 are naturally widespread in the Lower Talang Akar Formation (LTAF) and deposited in the Jabung Block, South Sumatra Basin, Indonesia. The different CO2 saturation contents stored in the reservoirs pose a challenge to planning future carbon capture and storage (CCS) and carbon capture, utilization, and storage (CCUS) in the area. This study integrates poststack 3D seismic data and existing wells in the western part of the Jabung Block. It utilizes seismic attribute methods such as sum of negative amplitude, relative impedance, variance, and ant tracking to predict the origin, saturation, and distribution of CO2-saturated hydrocarbon accumulations in the sandstone reservoirs of the LTAF. The results show that CO2 originated from the Betara Deep source rock in the study area's eastern side and migrated to the reservoirs through major northwest-southeast-Trending fault zones. The saturation of CO2 in the reservoirs is mainly controlled by the distance from the source and the reservoir depths, faulting, and fracturing intensity. The fields closer to the Betara source rock tend to be filled with higher contents of CO2 saturation. The results provide valuable guidance in CO2 identification and mapping for future CCS and CCUS implementation in the study area. © 2024 by The Society of Exploration Geophysicists.

关键词： Carbon capture

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The Effect of Land Degradation on Changes in Water Availability in Watershed Areas 1

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9th International Conference on Energy engineering and Environmental engineering, ICEEEE 2022

作者： Zainuddin Putranto, Dinar Dwi Anugerah Hadinata, Febrian Doctoral Program in Engineering Postgraduate Program Faculty of Engineering Universitas Sriwijaya Palembang Indonesia Department of Civil Engineering and Planning Faculty of Engineering Universitas Sriwijaya Palembang Indonesia

ISBN: (数字)9783031302336

ISBN: (纸本)9783031302329

Land degradation is defined as a condition in which the quantity and quality of land resources needed to support ecosystem functions and services and increase food security continues to decline on a temporal and spatial scale under certain ecosystem conditions (Sarino et al. in IOP Conf Ser Earth Environ Sci, pp 1–10, 2019). These changes, combined with population growth, have led to the conversion of agricultural land to developed land, high exploitation of natural and mineral resources, and urbanization, which usually leads to more significant land degradation (Putranto et al. in pp 100016-1–100016-10, 2017). Sub-watershed scale analysis related to the distribution of degraded land by utilizing multi-temporal geospatial layers (Putranto et al. in Int J Geomate 14(45):28–34, 2018) helps provide a regionally consistent data set of required land distribution. Therefore, it can support agendas aligned with sustainable development goals (SDGs) (Guo et al. in 11:1–20, 2019). By utilizing scientific big earth data, which is periodically integrated with terrestrial, aquatic, and hydrological data, it has the potential to assess degraded land as outlined in SDG’s target point 15.3.1 (Yuono et al. in J Ecol Eng 21:126–130, 2020). The Rawas sub-watershed is a river drainage area that originates at one of the peaks of Mount Kerinci. Geologically, the Rawas sub-watershed includes lowlands which are quarterly alluvial deposits from the Pleistocene to the present age. The availability of water in the Rawas watershed until 2020 is sufficient to serve the villages in the watershed. With the most significant water resource potential in November, December, and January to March, approximately 52 mm/month. Meanwhile, in other months, water availability in the Rawas watershed is below 3 mm/month and even close to 0 mm/month. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

关键词： Watersheds

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Effects on Cortical Rhythms Produced by Robotic Glove Assistance During Motor Imagery 1

Effects on Cortical Rhythms Produced by Robotic Glove Assist...

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1st IEEE Colombian Caribbean Conference, C3 2023

作者： Blanco-Diaz, Cristian F. Gonzalez-Cely, Aura X. Guerrero-Mendez, Cristian D. Souza, Fernanda Andrade, Diego Bastos-Filho, Teodiano F. Federal University of Espírito Santo Postgraduate Program in Electrical Engineering Vitoria Brazil

ISBN: (纸本)9798350341799

In recent years, advances in Brain-Computer Interfaces (BCIs) have gained recognition for the design of rehabilitation and/or assistance strategies for populations with neuromotor disabilities. In BCIs, the study of EEG phenomena during hand Motor Imagery (MI) tasks is still challenging. Therefore, to deepen the field, a novel protocol based on MI tasks is proposed in this study, which is compared to the classical MI protocol based on static Action Observation (AO). The proposed protocol is based on a combination of visual stimulation by AO and passive movements generated by a robotic glove. To address cortical effects, Electroencephalography (EEG) analysis was performed to examine the differences in cortical rhythms in the frequency domain. The results allow concluding that the use of the robotic glove generated a greater decrease in power (desynchronization) in the central parietal cortex of the brain, especially for electrode C3. These findings allow further neuroscience studies and will be used to deepen the analysis and detection of MI patterns towards a BCI-controlled upper limb assistance device. © 2023 IEEE.

关键词： Brain computer interface

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