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Addition of respiratory exercises to conventional rehabilitation for children and adolescents with cerebral palsy:a systematic review and meta-analysis

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World Journal of Pediatrics 2023年第4期19卷 340-355页

作者： Thálita Raysa de Lima Crispim Mansueto Gomes Neto Tafnes Rayane Lima Crispim Renivaldo Batista Dias Maria Déborah Monteiro de Albuquerque Micheli Bernardone Saquetto Paulo André Freire Magalhães Research Group of Neonatal and Pediatric Physical Therapy Baby GrUPEPetrolinaPernambucoBrazil Postgraduate Program in Rehabilitation and Functional Performance PPGRDFUniversidade de PernambucoRodovia BR 203Km 2 S/N.Vila EduardoPetrolinaPernambuco56328-900Brazil Research Group of Physiotherapy Department of Physical TherapyUniversidade Federal da BahiaSalvadorBrazil Posgraduate Program in Medicine and Health SalvadorBahiaBrazil

Background Respiratory dysfunctions are an important cause of morbidity and death in cerebral palsy(CP)*** exercises in addition to conventional rehabilitation have been suggested to improve respiratory status in CP *** objective of this systematic review and meta-analysis was to verify the effects of the addition of respiratory exercises to conventional rehabilitation on pulmonary function,functional capacity,respiratory muscle strength,gross motor function and quality of life in children and adolescents with *** We searched for randomized controlled clinical trials in PubMed/Medline,Lilacs,SciELO,EMBASE and Physi-otheraphy Evidence(PEDro)from their inception until July 2022 without language *** that included respiratory exercises(breathing exercise program;feedback respiratory training;incentive spirometer exercise;inspiratory muscle training;and combination of respiratory exercises+incentive spirometer exercise)in combination with conventional rehabilitation for children and adolescents with CP were evaluated by two independent *** mean difference(MD)and 95%confidence interval(CI)were estimated by random effect *** Ten studies met the eligibility criteria,including 324 children aged from 6 to 16 *** meta-analysis showed an improvement in inspiratory muscle strength of 22.96 cmH2O(18.63-27.27,n=55)and pulmonary function of 0.60(0.38-0.82,n=98)for forced vital capacity(L);0.22(0.06-0.39,n=98)for forced expiratory volume at 1 second(L);and 0.50(0.05-0.04,n=98)for peak expiratory flow(L/min).functional skills in daily living activities improved in the intervention ***'assistance of daily living activities,functional capacity,gross motor function and expiratory muscle strength showed a nonsignificant *** well-being and acceptance and functioning domains improved in only one *** Emerging data show significant enhancements in inspiratory muscle stren

关键词： Breathing exercises Cerebral palsy Inspiratory muscle training Pediatrics rehabilitation Respiratory exercise

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The effect of photobiomodulation auriculotherapy in the treatment of temporomandibular disorders: A double-blind randomized feasibility study

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Journal of Photochemistry and Photobiology 2023年 18卷

作者： Marques, Sara Lisboa Ramos, Andressa Cristine da Silva Boggiss, Érika Almeida de Lima, Rosana Aparecida Pinheiro-Araújo, Carina Ferreira Santos, Adriana Teresa Silva Terra, Andréia Maria Silva Vilela Postgraduate Program in Rehabilitation Sciences Institute of Motor Sciences Human Performance Research Laboratory Federal University of Alfenas Alfenas Brazil Physical Therapy Institute of Motor Sciences Human Performance Research Laboratory Federal University of Alfenas Alfenas Brazil Postgraduate Program in Rehabilitation and Functional Performance Department of Health Sciences Ribeirão Preto Medical School University of São Paulo Ribeirão Preto Brazil Medical Sciences Area of Concentration in Neurology - UNICAMP Postgraduate Program in Rehabilitation Sciences Institute of Motor Sciences Human Performance Research Laboratory Federal University of Alfenas Alfenas Brazil Postgraduate Program in Oral Biology from the Sacred Heart University Center Postgraduate Program in Rehabilitation Sciences Institute of Motor Sciences Human Performance Research Laboratory Federal University of Alfenas Alfenas Brazil

Introduction: Temporomandibular disorders (TMD) are considered the most common complaint associaetd with orofacial pain. A treatment approach for TMD is photobiomodulation auriculotherapy, however, a method that which still requires studies mainly with pulsed frequency. Objective: To evaluate the feasibility of conducting a randomized clinical trial using pulsed frequency photobiomodulation auriculotherapy and determine the relevant sample size. Methods: The study was a controlled randomized pilot study. Twenty one volunteers with TMD were randomized into experimental and placebo groups. The evaluation periods were pre-intervention and again after four weeks. The instruments used for the assessment were axis I (mandibular movement measurements [MMM]) and axis II (Graded Chronic Pain Scale [GCPS], Jaw functional Limitation Scale [JFLS-8], The Patient Health Questionnaire [PHQ-4], and Generalized Anxiety Disorder [GAD-7]) from Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Mann–Whitney and Wilcoxon tests were used for comparison of groups. The intervention protocol was performed once a week for foour weeks. Results: The GCPS question about “pain at this exact moment” indicated lower values for the treated group compared to the placebo group (U = 15.50;p = 0.005) after the intervention. The calculation of the total sample was 22 volunteers. The JFLS-8 variable showed no difference between the groups and the sample calculation ranged from 39 to 281 volunteers. The MMM showed no difference between the groups, and the calculation of the necessary sample ranged from 27 to 2.317. The variable PHQ-4 (U = 21.00;p = 0.02) and GAD-7 (U = 20.00;p = 0.02) showed differences between groups with type I error. The required sample was 22 volunteers for PHQ-4 and 25 for GAD-7. Conclusion: We conclude that this study is feasible and that the required sample should be 11 volunteers for each group in the GCPS subitem “pain intensity at this exact moment”. We were able to f

关键词： Auriculotherapy LASER rehabilitation Temporomandibular disorders

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Inflammatory biomarkers of osteosarcopenia in community-dwelling older woman

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Clinical Nutrition Open Science 2024年 55卷 173-182页

作者： Teixeira, Leonardo Augusto Costa Soares, Luana Aparecida Parentoni, Adriana Netto Nobre, Juliana Nogueira Pontes Figueiredo, Pedro Henrique Scheidt Leopoldino, Amanda Aparecida Oliveira Avelar, Nubia Carelli Pereira Mendonça, Vanessa Amaral Lacerda, Ana Cristina Rodrigues Postgraduate Program in Health Sciences (PPGCS) Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - nº 5000 Minas Gerais Diamantina 39100-000 Brazil Department of Physiotherapy Faculty of Biological and Health Sciences Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - nº 5000 Minas Gerais Diamantina 39100-000 Brazil Postgraduate Program in Rehabilitation and Functional Performance (PPGReab) Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - nº 5000 Minas Gerais Diamantina 39100-000 Brazil Faculty of Medical Sciences of Minas Gerais (FCMMG) Alameda Ezequiel Dias 275 Minas Gerais Belo Horizonte 30130-110 Brazil Department of Health Sciences Center for Science Technology and Health Federal University of Santa Catarina SC Araranguá 88906-072 Brazil

Background: The concomitant loss of lean muscle mass and bone mineral density is known as osteosarcopenia. This disorder can result in increased physical impairment in addition to an increased risk of falls and fractures. Although the diagnostic of osteoporosis and sarcopenia has been described, the inflammatory mediators that identify the presence of osteosarcopenia and propose possible inflammatory mechanisms implicated in muscle and bone loss are unknown. The objective of this study was to evaluate a panel of inflammatory biomarkers and investigate its relationship with the presence of osteosarcopenia. Methods: Body composition was assessed using Dual X-ray absorptiometry and handgrip strength using a Jamar dynamometer. Blood samples were collected for evaluation the plasmatic concentrations of adiponectin, brain-derived neurotrophic factor (BDNF), interferon ɣ (IFN), interleukins 2, 4, 5, 6, 8 and 10, leptin, resistin, tumour necrosis factor (TNF) and its soluble receptors (sTNFr) 1 and 2. Results: In seventy-one older women the age was 75 (±7) years, BMI 26.1 (±4.5) kg/m², handgrip strength 19 (±6) kgf and the muscle mass index was 6.39 (±1.05) kg/m². The diagnosis of osteosarcopenia was found in 25% of the sample. Analysis of the distribution of biomarkers demonstrate the osteosarcopenia group presented greater concentrations among all markers measured, and significant differences was found in plasmatic concentrations of interleukin 8 (p = 0.02). Subgroup analysis showed that group with osteopenia plus sarcopenia had significantly greater IL-6 (p = 0.03) and IL-8 (p = 0.007) concentrations. Conclusions: In a panel of biomarkers, IL-6 and IL-8 were found to be related with diagnosis of osteosarcopenia in community-dwelling older women. These results may contribute to understand the inflammatory mechanisms and suggest a diagnostic strategy for these patients, also informing new strategies for prevention, monitoring, and treatment of osteosa

关键词： Inflammation Osteopenia Osteoporosis Osteosarcopenia Sarcopenia

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Breaking barriers: Strength training feasibility in McArdle syndrome – A systematic review

Advanced Exercise and Health Science

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Advanced Exercise and Health Science 2024年第2期1卷 76-85页

作者： Danielle N. Ribeiro Adelino S.R. da Silva Ana Paula Pinto United Metropolitan College University Center (FMU) São Paulo Brazil School of Physical Education and Sport of Ribeirão Preto University of São Paulo (USP) Ribeirão Preto São Paulo Brazil Postgraduate Program in Rehabilitation and Functional Performance Ribeirão Preto Medical School University of São Paulo (USP) Ribeirão Preto São Paulo Brazil

The practice of physical fitness training plays a crucial role in the management of McArdle disease (MD), a metabolic myopathy characterized by myophosphorylase deficiency, which results in the reduction or absence of its activity in muscle tissue. Individuals affected by MD face challenges in using muscle glycogen stores, resulting mainly in symptoms of energy exhaustion. Exercise intolerance, fixed muscle weakness, and the phenomenon of 'second wind' are common manifestations. Seeking effective interventions is challenging, given the rarity of the condition. This systematic review aims to investigate the practicality and advantages of supervised resistance training for individuals with MD. To accomplish this, we conducted a comprehensive search of the PubMed and MedLine databases for pertinent studies. This review encompasses research examining the physiological adjustments in patients who engage in strength-building exercises and the short- and long-term adaptations associated with MD. Despite traditional precautions, emerging evidence suggests that exercise, especially strength training, can provide significant clinical benefits, challenging the conventional notion of avoiding physical activities. This article reviews the current literature, emphasizing the need for more comprehensive intervention studies in rare diseases like MD and highlighting the potential role of exercise as a fundamental therapeutic part in managing this condition.

关键词： McArdle ATP Muscle glycogen Lactate Muscle metabolism Early fatigue Creatine Nutrition Strength training

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Bariatric surgery and metabolic profile modulate mitochondrial plasticity of adipose tissue

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The Journal of physiology 2025年第11期603卷 2025 May 31页

作者： Ana Claudia Rossini-Venturini Caroline Fogagnolo Bianca Monteiro Silva Sofia Germano Travieso Marcela Coffacci de Lima Viliod School of Physical Education and Sport of Ribeirão Preto University of São Paulo (USP) Ribeirão Preto São Paulo Brazil. Ribeirão Preto Medical School Postgraduate Program in Rehabilitation and Functional Performance Ribeirão Preto Medical School University of São Paulo (USP) Ribeirão Preto São Paulo Brazil. Ribeirao Preto Medical School Postgraduate Program in Nutrition and Metabolism Ribeirão Preto Medical School University of São Paulo (USP) Ribeirão Preto São Paulo Brazil.

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AN INTERVENTION program WITH INTERACTIVE MEDIA FOR EARLY CHILDREN: A FEASIBILITY STUDY

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Brazilian Journal of Physical Therapy 2024年 28卷 100932-100932页

作者： Lima, Mylena Francielle Ribeiro Rocha, Lóren Beatriz Corrêa, Evelyn Daynnara Miranda da Costa, Lucas Barbosa Morais, Rosane Luzia Santos, Juliana Nunes Department of Physical Therapy Postgraduate Program in Rehabilitation and Functional Performance Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM) Diamantina Minas Gerais Brazil

Backgroundthe insertion of digital media devices has been increasingly prevalent in children's daily lives. The literature lacks evidence about the repercussion of media on children's development, therefore, further studies are needed to monitor the use and effect of these media. Objectiveto verify the viability of an intervention program based on active interactive media for children aged between 24 and 36 months. MethodsFeasibility study in which 32 children enrolled in the nursery II of the educational institution, aged 24 to 36 months, and their parents/guardians, were invited to participate this study. Children were randomized into two groups: 1) GMIA: children used media actively (games) and GMIP: children used media passively (viewing content). Both groups participated in the intervention for 30 minutes, twice a week, for 4 weeks. Measures: Primary outcome: feasibility of the study regarding the criteria related to the intervention program with interactive media. Secondary outcome: adherence, acceptability, structure, and adequacy of the program to the school environment; degree of satisfaction and acceptability of messages and links and preliminary child development outcomes. Before and after 4 weeks of intervention, the children were assessed for child development, receptive vocabulary, and analysis of the Daily Record Chart on the use of interactive media at home. ResultsOf the 32 eligible children, 22 children participated in the intervention, with an average of 17 children per meeting. As for acceptability, all parents (n= 32) signed the informed consent form, however, only 15 children (46.8%) were able to complete all stages of the program. As for the suitability of the proposal to the school environment, it was adapted after minor adjustments to the environment. Regarding the structure of the program, an “ideal” duration of 30 minutes of interventions was observed and that the children's interest was greater in the active media group. Most parents repo

关键词： Tablet Child development Viability study

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QUALITY OF LIFE OF CAREGIVERS OF CHILDREN AND ADOLESCENTS WITH CANCER

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Brazilian Journal of Physical Therapy 2024年 28卷 100704-100704页

作者： Chiari, Devika Prem Chandiramani de Resende, Beatriz El'Corab Muniz, Maria Eduarda de Araujo Almeida Saraiva, Beatriz Bicalho Defilipo, Érica Cesário Chagas, Paula Silva de Carvalho Department of Physical Therapy Postgraduate Program Rehabilitation Sciences and Physical-Functional Performance Universidade Federal de Juiz de Fora (UFJF) Juiz de Fora Minas Gerais Brazil

BackgroundChildren and adolescents with cancer have to deal with the adverse events of the disease and treatments, and low immunity predisposes them to the development of serious forms of infections, that can cause physical damage, negative repercussions on health care and on the quality of life of them and their caregivers. ObjectivesTo evaluate the quality of life of caregivers of children and adolescents with cancer. MethodsObservational, cross-sectional study, carried out from October to December 2022. We used social media, WhatsApp, and emails to invite caregivers of children and adolescents with cancer aged between 2 and 21 years. The survey was performed remotely, through the application of an online form that contained personal and sociodemographic data, the SF-36 questionnaire for assessing the quality of life of the caregivers. ResultsThirty caregivers participated in the study, with a higher prevalence of females (86.7%). The caregiver's quality of life averaged 55.15 (SD=20.35), which represents a moderate to low quality of life. The worst quality of life scores of caregivers was observed in the domains "Vitality (45.17±XX)", "Emotional Aspects (45.55±XX)", and "Limitation due to Physical Aspects (48.33±XX)". ConclusionThe quality of life of the caregivers of children and adolescents with cancer was moderate to low, related to impairment of vitality, emotional aspects, and limitation due to physical aspects. Strategies to improve the quality of life of caregivers of children and adolescents with cancer should be considered, therefore improving the integral care for this population and the caregivers. ImplicationsConducting further studies on quality of life in relation to other health conditions that may affect physically and mentally caregivers of individuals with childhood cancer may provide help to develop personalized rehabilitation programs for family's pediatric cancer patients.

关键词： Childhood cancer Health Quality of life

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RELATIONSHIP BETWEEN MAXIMUM MUSCLE STRENGTH AND FREQUENCY SPEED OF KICK TEST FOR BLACK BELT TAEKWONDO ATHLETES

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Brazilian Journal of Physical Therapy 2024年 28卷 100798-100798页

作者： Antonaccio, Romulo Fernandes Santos, Jonatas Ferreira da Silva Physical Training and Sport Performance Research Group Physical Education Department Health and Biological Science Faculty Postgraduate Program in Rehabilitation and Functional Performance Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM) Diamantina Minas Gerais Brazil

BackgroundTaekwondo is a predominantly aerobic combat sport modality (58-66%) in which high-intensity actions are performed with the contribution of the anaerobic alactic system (26-30%) followed by the contribution of the anaerobic lactic metabolism (4-5%). High-intensity actions are performed repeatedly with muscular power and short duration. Thus, seeking to understand the relationship between the variables that represent maximum muscle strength, and the aerobic capacity of taekwondo athletes is relevant for a better understanding of the modality. ObjectivesThe aim of this study was to determine whether the 10-second Frequency Speed of Kick Test (FSKT 10s) correlates with maximal muscle strength in black belt taekwondo athletes. MethodsNine male athletes (age: 20.3 ± 5.2 years; height: 177 ± 7.2 cm; body mass: 71.8 ± 15.3 kg and practice time: 9.6 ± 7.2 years) who competed at the state level or more prominently (international: 73%; national: 9%; state: 18%) participated in the study. All were free of any lower limb injury and had no neuromuscular disorder. Maximum muscle strength was achieved in the half-squat exercise, as previously described in the literature. FSKT 10s is 10s long, alternating semi-circle kicks between right and left segments on a dummy using a simple torso protector, as often seen in taekwondo matches. Each participant was instructed to read and sign the Informed Consent Form with information about the procedures and risks associated with the study. The Kolmogorov-Smirnov test was used to assess data normality. Pearson's correlation was used to determine the relationship between selected variables. Correlations were classified as follows: 0.0 – 0.1 (trivial), >0.1 – 0.3 (minor), >0.3 – 0.5 (moderate), >0.5 – 0.7 (large), >0.7 – 0.9 (very large), and >0.9 – 1.0 (perfect). For all analyzes an α = 5% was adopted. ResultsThe athletes reached 133±33 kg (95% CI: 108 – 158) during the maximal strength test performed in the half-squat exercise. Values

关键词： Combat sport Martial art Sports performance

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INFLUENCE OF PHOTOBIOMODULATION ON CELL VIABILITY OF MULTIPOTENT MESENCHYMAL STEM CELLS FROM ADIPOSE TISSUE IN VITRO

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Brazilian Journal of Physical Therapy 2024年 28卷 100627-100627页

作者： Ferro, Ana Paula Rangon, Flávia Belavenuto Mestriner, Carolina Fernandes Zordão, Catarina Clapis Guirro, Elaine Caldeira de Oliveira Department of Health Sciences Postgraduate Program in Rehabilitation and Functional Performance Ribeirão Preto Medical School University of São Paulo (USP-RP) Ribeirão Preto São Paulo Brazil

BackgroundThe use of mesenchymal stem cells (MSCs) has been an alternative to conventional therapeutic modalities for wound healing, with recent advances in cellular and molecular biology to aid in tissue repair. The use of photobiomodulation (FBM) is used in the healing process by modulating cell metabolism through photochemical action, but many parameters and inappropriate use can disrupt this process, and there is no standardization for the application of the LASER to assist in the healing process. Objectiveto investigate the effect of different energies of LASER photobiomodulation on mesenchymal stem cells, which play a key role in the healing process. MethodsMesenchymal stem cells were cultured in αMEM medium with 10% FBS (Fetal bovine serum), penicillin, and streptomycin. Cells were incubated at 37 °C in an 80% humidified atmosphere containing 5% CO 2 in the dark, until reaching 90% confluence. The 3 groups with a wavelength of 830 nm were submitted to LASER applications: G1: 0.5 J, G2: 2 J and G3: 4 J, with irradiation at 24 and 48 hours. The cells were stained with markers for viable cells (Hoechst) and dead cells (Propidium Iodide. The analysis of the plates with MSCs was performed with the MetaXpress® software at 48 and 72 hours, and the statistical analyses were performed with the software GraphPad Prism® 7.0. ResultsThe results obtained in the experiments showed that irradiation with the 830 nm wavelength laser showed an increase in cell viability at 48 and 72 hours compared to the control group and showed a significant difference when using 2 J energy. ConclusionPhotobiomodulation assists in increasing cell viability when using the correct parameters, capable of assisting in the process of tissue regeneration. ImplicationThe use of appropriate parameters influences the cellular response and consequently the effectiveness of the treatment.

关键词： Low-level laser therapy Cell survival Tissue healing

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ACUTE EFFECT OF AEROBIC AND/OR RESISTANCE EXERCISE ON BLOOD GLUCOSE IN INDIVIDUALS WITH TYPE 2 DIABETES: A SYSTEMATIC LITERATURE REVIEW

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Brazilian Journal of Physical Therapy 2024年 28卷 100805-100805页

作者： de Almeida, Josiane A. Batalha, Ana Paula D.B. Santos, Carolina V.O. Fontoura, Tamiris S. Laterza, Mateus C. da Silva, Lilian P. Postgraduate Program in Rehabilitation Sciences and Physical-Functional Performance Faculty of Physical Therapy Federal University of Juiz de For a (UFJF) Juiz de Fora Minas Gerais Brazil Postgraduate Program in Physical Education Faculty of Physical Education and Sports Federal University of Juiz de Fora (UFJF) Juiz de Fora Minas Gerais Brazil Postgraduate Program in Health Faculty of Medicine Federal University of Juiz de Fora (UFJF) Juiz de Fora Minas Gerais Brazil

BackgroundType 2 diabetes (T2DM) is the most prevalent type of diabetes worldwide. Its treatment aims to control glycemic levels, with regular physical exercise being one of its pillars. The hypoglycemic effect of physical exercise varies according to the intensity, duration, type, and time of day it is performed. ObjectivesSynthesize the scientific evidence on the effect of a single session of continuous (AEc) or interval (AEi) aerobic exercise and/or resistance exercise (RE) on post-exercise glycemia in individuals with T2DM. MethodsThe study protocol (CRD42022289985) followed PRISMA guidelines. The search strategies were elaborated from the acronym PICO (P: individuals ≥ 18 years old with DM2; I: a single session of aerobic and/or resistance exercise; C: no exercise or any exercise that did not meet the characteristics of the intervention; O: glycemia measured before and up to 24h post-exercise). The electronic databases CINAHL, Cochrane Library, EMBASE, Google Scholar, LILACS, MEDLINE/Ovid, SciELO, SPORTDiscus, and Web of Science were searched, including randomized and non-randomized clinical trials published from the inception of the databases until February 2022, without limitation of language. The “Risk of Bias” tool was used to assess the risk of bias in the included studies. Reduction or no significant change in post-exercise glycemia is expressed as (↓) or (↔), respectively. Results25 articles published between 1997 and 2021 were included from 6,237 retrieved from the literature. The total sample consisted of 424 participants (men = 290, women = 119, unreported = 15) aged between 21 and 70 years, with mean values of glycated hemoglobin between 6.0±0.3% and 10.4± 3.0% and body mass index between 22.2±2.3 and 37.0±5.7 kg/m². The duration of the exercise sessions varied between 10 and 60 minutes, with moderate to high intensities, and most (72%) were performed in the morning. Thirteen studies investigated AEc vs. control [glycemia: AEc ↓, control ↔ (n=10); AE

关键词： Diabetes Mellitus, Type 2 Exercise Systematic Review

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