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THE ESCAPE TRIAL FOR OLDER PEOPLE WITH CHRONIC LOW BACK PAIN: PROTOCOL OF A RANDOMIZED CONTROLLED TRIAL

Brazilian Journal of Physical Therapy 2024年 28卷 100760-100760页

作者： Silva, Hytalo de Jesus Fonseca, Leticia Soares de Miranda, Júlio Pascoal Pereira, Leani Souza Maximo Oliveira, Murilo Xavier Oliveira, Vinicius Cunha Postgraduate Program in Health Sciences Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Postgradute Program in Rehabilitation and Functional Performance Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Postgradute Program in Rehabilitation Sciences Universidade Federal de Minas Gerais (UFMG) Belo Horizonte Minas Gerais Brazil

BackgroundLow-back pain is one of the most common health conditions worldwide. It is defined as pain below the costal margin and above the inferior gluteal folds. Current guidelines recommend management of chronic health (e.g., low back pain) conditions in older people at primary health care settings using active strategies (e.g., exercise). In non-specific low back pain, high quality evidence supports active strategies for general population. However, the management of non-specific low back pain in older people has been overlooked and evidence is limited to a small number of low powered randomized controlled trials with high risk of bias. ObjectivesThe primary outcomes will be pain intensity over the previous week and disability. The secondary outcomes will be: Global impression of recovery; frequency of falls; fear of falling; and Physical Active level. MethodsThis is a prospectively registered, open, two-arm randomized controlled trial comparing the group-based exercise and waiting list. The randomization sequence to our two groups of interest (i.e., group-based exercise or control) will be computer-generated by one of the investigators who will not be involved in the recruitment of participants. The sequence will be blocked (block sizes of 4, 6, and 8, in random order). Allocation will be concealed in sequentially numbered, sealed, opaque envelopes. Participants will be stratified by gender (female or male). The GBE comprises three sessions per week of group-based exercise in a local community center, for 8 weeks. Each group session will consist of 10 to 18 participants and each exercise session will last 60 minutes and consist of four stages: (1) five minutes warm up (i.e., self-regulated walk); (2) twenty minutes of moderate intensity walking; (3) thirty minutes of resistance training for the major muscles of the leg, trunk and arm and balance exercises that progress in difficulty; and (4) five-minute cool down period (i.e., self-regulated walk). Participants

关键词： Low back pain Older people Disability

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RANDOMIZED CONTROLLED TRIAL PROTOCOL: EFFECTIVENESS OF CRYOTHERAPY ON FUNCTION, PAIN, EDEMA AND RANGE OF MOTION IN ACUTE ANKLE STRAIN

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Brazilian Journal of Physical Therapy 2024年 28卷 100819-100819页

作者： de Miranda, Júlio Pascoal Gontijo, Fabiane Correa Figueiredo, Rafaela Calixto Cortez Coelho, Germano Martins Silva, Hytalo de Jesus de Oliveira, Vinicius Cunha Postgraduate Program in Rehabilitation and Functional Performance Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Medicine College Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Postgraduate Program in Health Sciences Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil

BackgroundAnkle sprain is a common condition in the general population, with a prevalence of 11.88%, and an incidence of seven sprains per 1000 exposures in athletes, resulting in a high frequency of chronic ankle instability. Therefore, effective therapies are increasingly sought after by clinicians. Cryotherapy is a low-cost and easy-to-use treatment option, being considered a potentially effective therapy in the acute inflammatory phase due to preclinical research findings, which suggest that cryotherapy can control inflammatory processes and promote local analgesia by decreasing nerve conduction velocity, which could lead to improved clinical outcomes. However, the current literature lacks evidence on clinical outcomes to support its use, raising the importance of new randomized controlled trials with low risk of bias and appropriate comparator groups. ObjectivesThe aim of this not applied study protocol is to investigate the effectiveness of cryotherapy on function, pain intensity, swelling, and dorsiflexion range of motion in people with an acute episode of ankle sprain. MethodsThis is a two-arm prospective randomized controlled trial protocol, designed according to the SPIRIT guideline. People over 18 years old with a clinical diagnosis of grade I or II ankle sprain, and time of up to 72 hours from the injury episode, will be randomly allocated in the Ice Group, which consists of home medical prescription of immersion of the ankle in an ice bucket or, secondarily, ice packs, combined with elevation and non-steroidal anti-inflammatory drugs or to the No-Ice Group, which consists of the same medical prescription as the experimental group, but with no ice included. Our primary outcome is function, as measured by the Lower Extremity functional Scale (LEFS). Our secondary endpoints are pain intensity (Numeric Pain Scale, 0-10), swelling (figure-of-eight method), and dorsiflexion range of motion (goniometry). Follow-ups will be performed at post-treatment (7 to 14

关键词： Cryotherapy Ankle injuries Randomized Controlled Trial

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EFFECTIVENESS OF CRYOTHERAPY ON FUNCTION, PAIN, EDEMA AND RANGE OF MOTION IN ACUTE ANKLE STRAIN: FROST RANDOMIZED CONTROLLED TRIAL PROTOCOL

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Brazilian Journal of Physical Therapy 2024年 28卷 100820-100820页

作者： de Miranda, Júlio Pascoal Silva, Whesley Tanor Mascarenhas, Rodrigo Oliveira Silva, Hytalo de Jesus Oliveira, Vinicius Cunha de Postgraduate Program in Rehabilitation and Functional Performance Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Department of Physiotherapy Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Postgraduate Program in Health Sciences Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil

BackgroundAnkle sprain is a condition with a high incidence in the general population and athletes and can cause direct costs (expenses with medical appointments and medication) and indirect costs (absence from work and loss of productivity). Cryotherapy is often recommended for the management of this condition, however current evidence supporting cryotherapy is still uncertain. A systematic review is needed to inform clinicians and patients about the current quality of evidence for the effectiveness of cryotherapy after an episode of an acute ankle sprain. ObjectivesThe aim of this systematic review was to investigate the effectiveness of cryotherapy on pain, edema, range of motion, function, and recurrence after acute ankle sprains. MethodsThis systematic review of randomized controlled trials was reported following the PRISMA checklist and some stages were conducted according to the Cochrane recommendations. Protocol was prospectively registered in PROSPERO (CRD42020166411) and Open Science Framework (https://***/x6p23). Searches for randomized controlled trials evaluating the effectiveness of cryotherapy on pain, swelling, range of motion, function, and recurrence outcomes in people with acute ankle sprains were performed in six databases (MEDLINE, COCHRANE, EMBASE, AMED, PSYCINFO and PEDRO, without language or date restriction, until January 2021). Study selection, data extraction, and assessment of the methodological quality of included studies were conducted independently by two reviewers, with discrepancies resolved by a third reviewer. Estimates were presented as Difference of Means (MDs) with 95% confidence intervals (CIs). The quality of evidence was assessed using the GRADE approach. ResultsTwo randomized controlled trials with a high risk of bias (methodological quality < 6 on the 0-10 PEDro scale) were included. There were no studies investigating the effectiveness of cryotherapy alone on our outcomes of interest. Both studies evaluated the addition

关键词： Cryotherapy Ankle injuries Randomized Controlled Trial

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Social isolation as a risk factor for neck and low back pain: a cotwin design

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Brazilian Journal of Physical Therapy 2024年 28卷 100939-100939页

作者： Alves, Natália Christina Moura Dario, Amabile Borges Ferreira, Paulo Henrique Ferreira, Lucas Calais Oliveira, Vinícius Cunha Postgraduate Program in Rehabilitation and Functional Performance Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Diamantina Minas Gerais Brazil Faculty of Health Sciences The University of Sydney Sydney Australia Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health The University of Melbourne Melbourne Australia

BackgroundPerceived social isolation (PSI) is a personal contextual factor that is associated with morbidity and mortality. It is a factor that contributes to a worse quality of life for individuals, being associated with a worse prognosis for several clinical conditions, including low back pain (LBP) and neck pain (NP). However, information on whether ISP is a possible risk factor for LBP and NP is scarce. The few studies that investigated social isolation in back pain have scope or methodological limitations. ObjectivesTo investigate the association between individual ISP and the presence of LBP and NP through a co-twin study. MethodsCross-sectional observational study of 141 pairs of complete twins. The sample was taken from the Brazilian Twin Registry. We used self-reported questionnaires to assess the occurrence of LBP and NP (yes or no) and the level of physical activity. The Friendship Scale was used to measure people's PSI. The Peas in a Pod and Pittsburgh Sleep Quality questionnaires were used to determine twin pair zygosity and sleep quality, respectively. Regression models were constructed to investigate whether people's ISP is associated with the occurrence of LBP or NP. Models were adjusted for potential confounders: family factors; age; gender; level of physical activity; and sleep quality. ResultsThe sample consisted of adults of good socioeconomic status, mostly female (73.76%). Most had LBP and/or NP (84.75%), social isolation (58.87%), poor sleep quality (62.42%) and did not practice regular physical activity (69.15%). A change of one point in 25 in people's perception of less social isolation represented a 6% reduction in the risk of having NP (OR:0.94; 95%CI:0.84–1.05) and an 8% reduction in risk to present LBP (OR :0.92; 95%CI:0.81–1.05), after adjusting models for possible confounding factors mentioned above, however the confidence intervals included 1.0, so the estimates did not reach significance statistic. ConclusionOur study is the first to

关键词： Social isolation Neck Pain Low Back Pain

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DORSIFLEXION RANGE OF MOTION (ROM) AND SHANK-FOREFOOT ALIGNMENT ARE ASSOCIATED WITH THE performance OF THE MODIFIED STAR EXCURSION BALANCE TEST

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Brazilian Journal of Physical Therapy 2024年 28卷 100827-100827页

作者： Alves, Laís Emanuelle Meira Bittencourt, Natália Franco Netto da Silva, Renato de Paula Mendonça, Luciana De Michelis Postgraduate Program in Rehabilitation and Functional Performance (PPGReab) – Universidade Federal dos Vales do Jequitinhonha e do Mucuri (UFVJM) Diamantina Minas Gerais Brazil Department of Health and Performance in Clube Esporte Bahia Salvador Bahia Brazil Postgraduate Program in Sports Science (PPGCE) Universidade Federal de Minas Gerais (UFMG) Belo Horizonte Minas Gerais Brazil Department of Physical Therapy – School of Physical Education Physiotherapy and Occupational Therapy - Universidade Federal de Minas Gerais (UFMG) Belo Horizonte Minas Gerais Brazil

BackgroundThe modified Star Excursion Balance Test (mSEBT) is a valid, low-cost, and easily implemented screening tool in clinical practice recommended for assessing dynamic postural control in athletes. Previous studies evidenced that poorer performance on the mSEBT predicts an increased risk of injury in several sports. The performance of the mSEBT depends on the contribution of various body segments and constructs of physical function to reach maximum distance in the anterior, posteromedial, and posterolateral directions. Understanding the relationship between mSEBT performance, distal and proximal factors in the kinetic chain and other constructs of physical function in soccer athletes can contribute to a more assertive assessment in clinical practice, since soccer athletes with dynamic balance deficient are more likely to sustain a lower limb injury. ObjectiveTo verify if hip and foot/ankle musculoskeletal factors predicts the performance of the modified Star Excursion Balance Test (mSEBT) in male youth soccer athletes. MethodsIn this cross-sectional study, 108 athletes (18.04 ± 0.14 years, 72.86 ± 0.76 kg, 1.78 ± 0.7 m) in categories Under-17 and Under-20 from a professional soccer club in Brazil were assessed during the preseason assessment. The assessment included the following tests: shank-forefoot alignment (SFA), passive hip IR ROM, hamstring flexibility (HF), dorsiflexion range of motion (ROM), Single Leg Hamstring Bridge (SLHB), and the performance of the modified Star Excursion Balance Test (mSEBT). Multiple linear regression analysis was performed to identify if the foot/ankle musculoskeletal factors could explain the performance of the mSEBT. ResultsRegression analyses revealed that shank-forefoot alignment and ankle dorsiflexion ROM predicted the performance of the mSEBT (P < 0.05). In model 1, SFA explained 9% of the mSEBT performance (F = 10.19; r = 0.3; r 2 = 0.9; p = 0.002). The inclusion of the ankle dorsiflexion ROM in model 2 explained 16% of

关键词： Postural control Assessment Kinetic chain

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Internal consistency, minimal detectable change, and sensitivity to change of the Spanish version of the Barthel Index at intensive care unit discharge and three months later

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Enfermería Intensiva (English ed.) 2025年第2期36卷

作者： Esther Cecilia Wilches-Luna Vilma Eugenia Muñoz-Arcos Paula Benavides-Candezano José Julián Bernal-Sánchez Ada Clarice Gastaldi Universidad del Valle Facultad de Salud Escuela de Rehabilitación Humana Cali Colombia Grupo de Investigación Ejercicio y Salud Cardiopulmonar (GIESC) Cali Colombia Universidad Santiago de Cali Facultad de Salud Programa de Fisioterapia Cali Colombia Biomedical Sciences Faculty of Health Universidad del Valle Cali Colombia Faculty of Health Universidad del Valle Cali Colombia Universidad de São Paulo Department of Health Sciences Postgraduate Program in Rehabilitation and Functional Performance Ribeirão Preto SP Brazil

Objective To determine the internal consistency (IC), minimal detectable change (MDC), and sensitivity to change of the Barthel Index (BI) at ICU discharge and three months post-hospital discharge. Methods A prospective longitudinal study was conducted between November 2016 and July 2017 in a medical-surgical intensive care unit (ICU). A total of 149 patients over 18 years with a BI score >90 prior to ICU admission were included. The COSMIN checklist was utilized to evaluate the measurement properties. Clinical and demographic variables, BI scores, IC, MDC, and sensitivity to change were analyzed. The Cronbach's alpha coefficient ( α ) was calculated to determine the IC of the BI by domain and for the overall scale. Effect size (ES) indices and standardized mean response (SMR) were used for sensitivity to change. The MDC was identified using a distribution-based method, calculating the standard error of measurement (SEM). Floor and ceiling effects were assessed, with a threshold of less than 15% considered acceptable. Results A total of 141 patients were evaluated at discharge from the ICU. Of these, n = 77 (41.7%) were men, with a mean age of 58.5 ± 16.8 years; n = 62 (41.6%) required invasive mechanical ventilation. One hundred twelve patients were reassessed three months after discharge. The overall IC was: α = 0.70 at ICU discharge and α = 0.96 at three months. Ninety two percent ( n = 103) of the patients showed values greater than or equal to the MDC of 10 points, with statistically significant differences identified in the type of weaning, tracheostomy, and length of stay in the ICU ( p < 0.005). Conclusions The items of the Spanish version of the BI demonstrate acceptable IC at ICU discharge. The MDC was 10 points, validating its responsiveness and utility for monitoring the functional independence of critically ill patients at ICU discharge and three months after hospital discharge. Objetivo Determinar la consistencia interna (CI

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Analysis of the diagnostic accuracy of plasma sTNFr-2 concentrations in identifying sarcopenia in community-dwelling older women

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Scientific Reports 2025年第1期15卷 1-8页

作者： da Costa Teixeira, Leonardo Augusto Soares, Luana Aparecida Silveira Costa, Henrique Nobre, Juliana Nogueira Pontes Alves Viegas, Ângela de Avelar, Núbia Carelli Pereira Scheidt Figueiredo, Pedro Henrique Netto Parentoni, Adriana Mendonça, Vanessa Amaral Lacerda, Ana Cristina Rodrigues Postgraduate Program in Health Sciences (PPGCS) Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - no 5000 Minas Gerais Diamantina 39100-000 Brazil Exercise Physiology Laboratory (LAFIEX) of the Integrated Center for Research and Postgraduate Studies in Health (CIPq-Saúde) of the Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - no 5000 Minas Gerais Diamantina 39100-000 Brazil Inflammation and Metabolism Laboratory (LIM) of the Integrated Research and Postgraduate Center (CIPq-Saúde) of the Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - no 5000 Minas Gerais Diamantina 39100-000 Brazil Postgraduate Program in Rehabilitation and Functional Performance (PPGReab) Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - no 5000 Minas Gerais Diamantina 39100-000 Brazil Department of Physiotherapy Faculty of Biological and Health Sciences Federal University of the Jequitinhonha and Mucuri Valleys MGC 367 Km 583 - no 5000 Minas Gerais Diamantina 39100-000 Brazil Department of Physical Education Federal University of Bahia (UFBA) Av Reitor Miguel Calmon Bahia Canela Salvador 40110-100 Brazil Department of Physical Therapy Federal University of Santa Catarina Santa Catarina Araranguá 88906-072 Brazil

While the potential of immunological biomarkers as an alternative to aid in the diagnosis, treatment, and monitoring of sarcopenia has been explored, there are still few studies evaluating their diagnostic accuracy. Specific biomarkers and diagnostic cutoff points remain unknown. Therefore, the objective of the present study was to verify the association between sarcopenia and a panel of inflammatory biomarkers and to investigate the diagnostic accuracy to propose cutoff points for this assessment. Accordance with EWGSOP2 guidelines, 71 community-dwelling older women participated in the study and were assessed for sarcopenia diagnosis. Dual-energy X-ray Absorptiometry (DXA), a Jamar dynamometer, and the Short Physical performance Battery were used for diagnosis and classification of sarcopenia. A panel of biomarkers, including adiponectin, BDNF, IFN, IL-2, -4, -5, -6, -8, -10, leptin, resistin, TNF-α, and their soluble type 1 and 2 receptors, was measured using ELISA and flow cytometry. The associations between sarcopenia and a panel of biomarkers were verified by logistic regression analysis, and the cutoff points were determined using the ROC curve and Youden index. The sTNFr-2 was significantly associated with sarcopenia, showed good diagnostic accuracy and the optimal discriminatory cutoff point (AUC = 0.75) found was 2280 pg/ml in community-dwelling older women. These results provide valuable insights for the diagnosis, monitoring and understanding of the pathophysiology of sarcopenia in community-dwelling older women. © The Author(s) 2025.

关键词： Diagnosis Inflammation Sarcopenia SDG-10: reduced inequalities SDG-3: health and well-being sTNFr-2

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Physical and inflammatory aspects associated to respiratory sarcopenia in community-dwelling older women

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Scientific Reports 2025年第1期15卷 1-10页

作者： da Costa Teixeira, Leonardo Augusto de Carvalho Bastone, Alessandra Soares, Luana Aparecida dos Santos Mourão, Maria Fernanda Nobre, Juliana Nogueira Pontes Viegas, Ângela Alves Parentoni, Adriana Netto Figueiredo, Pedro Henrique Scheidt Taiar, Redha Mendonça, Vanessa Amaral Lacerda, Ana Cristina Rodrigues Postgraduate Program in Health Sciences Federal University of Vales do Jequitinhonha and Mucuri (UFVJM) MGT Highway 367 - Km 583 nº 5000 39.100-000 Minas Gerais Diamantina Brazil Postgraduate Program in Rehabilitation and Functional Performance Federal University of Vales do Jequitinhonha and Mucuri (UFVJM) MGT Highway 367 - Km 583 nº 5000 39.100- 000 Minas Gerais Diamantina Brazil Department of Physiotherapy Federal University of Vales do Jequitinhonha and Mucuri MGT Highway 367 - Km 583 nº 5000 39.100-000 Minas Gerais Diamantina Brazil Exercise Physiology Laboratory (LAFIEX) of the Integrated Center for Research and Postgraduate Studies in Health (CIPq-health Federal University of the Jequitinhonha Mucuri Valleys. MGT Highway 367 - Km 583 nº 5000 39.100-000 Minas Gerais Diamantina Brazil Inflammation and Metabolism Laboratory (LIM) of the Integrated Center for Research and Postgraduate Studies in Health (CIPq-health Federal University of the Jequitinhonha Mucuri Valleys. MGT Highway 367 - Km 583 nº 5000 39.100-000 Minas Gerais Diamantina Brazil Department of Physical Education Federal University of Bahia Av Reitor Miguel Calmon Canela Bahia Salvador 40110-100 Brazil Materials and Mechanical Engineering (MATIM) University of Reims Champagne Ardenne Reims 51100 France

To investigate the relationship between respiratory sarcopenia with physical tests and a set of inflammatory biomarkers, seventy-one older women from the community with age 75 ± 7 years and BMI 26 ± 4 kg/m² were evaluated for appendicular lean mass using Dual X-ray Absorptiometry, respiratory muscle strength using an analog manuvacuometer, physical tests using handgrip strength, timed up and go and sit to stand in chair tests, and a panel of inflammatory biomarkers was measured, containing Adiponectin, BNDF, IFN, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, Leptin, Resistin, TNF and their soluble receptors sTNFr-1 and sTNFr-2. The analyzes suggest that older women with respiratory sarcopenia also had significantly low physical function and higher concentrations of sTNFr-2 (> 2241pg/ml), additionally respiratory muscle strength was inversely associated with sTNFr-2 concentrations (MIP: β = -0.48;R² = 0.24;p < 0.001;MEP: β = -0.35;R² = 0.12;p = 0.003). These results contribute to the discussion about the pathophysiology and to the strategies for diagnosing and monitoring respiratory sarcopenia in community-dwelling older women. © The Author(s) 2025.

关键词： Diagnosis Inflammation Physical performance Respiratory sarcopenia SGD3-10 sTNFr-2

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WITHDRAWN: Correlation of the torque peak of the isokinetic dynamometer with the peak of ground reaction force in the drop vertical jump in professional futsal players

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Physical Therapy in Sport 2020年 45卷 e3-e3页

作者： Vieira, Arthur Manzini Luiz de Souza Bedo, Bruno Mariano, Fábio Pamplona de Souza Serenza, Felipe Palucci Vieira, Luiz Henrique Pereira Santiago, Paulo Roberto Ribeirão Preto Medical School – Physiotherapy Department Postgraduate program in Rehabilitation and Functional Performance – Ribeirão Preto Medical School School of Physical Education and Sport of Ribeirão Preto

The Publisher regrets that this article is an accidental duplication of articles which have already been published in Physical Therapy in Sport (2018) e1-e7 http://***/10.1016/***.2020.04.013. The duplicate articles have therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://***/about/our-business/policies/article-withdrawal.

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Correlation of the torque peak of the Isokinetic Dynamometer with the peak of ground reaction force in the drop vertical jump in professional futsal players

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Physical Therapy in Sport 2018年 31卷 e2-e3页

作者： Vieira, Arthur Manzini de Souza Bedo, Bruno Luiz Mariano, Fábio Pamplona de Souza Serenza, Felipe Palucci Vieira, Luiz Henrique Pereira Santiago, Paulo Roberto Ribeirão Preto Medical School – Physiotherapy Department Brazil Postgraduate program in Rehabilitation and Functional Performance – Ribeirão Preto Medical School Brazil School of Physical Education and Sport of Ribeirão Preto Brazil

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