检索结果-内蒙古大学图书馆

Corrigendum to "Effect of cell imprinting on viability and drug susceptibility of breast cancer cells to doxorubicin" [Acta Biomaterialia, 2020, 113, 119-129] (Acta Biomaterialia (2020) 113 (119–129), (S1742706120303287), (10.1016/***.2020.06.007))

引用

Acta Biomaterialia 2025年 198卷 571-572页

作者： Shahriyari, Fatemeh Janmaleki, Mohsen Sharifi, Shahriar Hesar, Milad Eyvazi Hoshian, Sasha Taghiabadi, Reza Razaghian, Ahmad Ghadiri, Majid Peirovi, Afshin Mahmoudi, Morteza Nezhad, Amir Sanati Khademhosseini, Ali Division of Engineering in Medicine Department of Medicine Brigham and Women's Hospital Harvard Medical School CambridgeMA United States Division of Health Sciences & Technology Harvard-Massachusetts Institute of Technology Massachusetts Institute of Technology CambridgeMA United States Department of Materials Engineering Faculty of Engineering Imam Khomeini International University Qazvin Iran Biomedical Engineering Graduate Program University of Calgary Canada Precision Health Program and Department of Radiology Michigan State University East LansingMI48824 United States RWTH Aachen University Templergraben 55 Aachen52062 Germany Department of Chemistry and Materials Science Aalto University School of Chemical Engineering Espoo Finland Department of Mechanical Engineering Faculty of Engineering Imam Khomeini International University Qazvin Iran Nano-Biotechnology Department Pasteur Institute of Iran Tehran Iran Departments of Bioengineering Chemical and Biomolecular Engineering and Radiological Sciences Center for Minimally Invasive Therapeutics California NanoSystems Institute University of California – Los Angeles Los AngelesCA United States Terasaki Institute for Biomedical Innovation Los AngelesCA United States

The authors regret to report that the images for panels h (Plain PDMS) and I (MCF7-imprinted PDMS) in Fig. 3 were mistakenly taken from the same dataset, resulting in the omission of the correct image in panel h for the Plain PDMS day 7 image. We sincerely apologize for this error. For an accurate representation, please see the corrected Fig. 3 provided here along with its original figure caption. This does not affect the validity of the statistical analyses or the overall conclusions drawn from the study. © 2025

关键词：

来源：评论

学校读者我要写书评

暂无评论

STABLE AND SCALABLE engineering OF HUMAN PRIMARY T CELLS VIA MICROFLUIDIC CELL STRETCHING 25

STABLE AND SCALABLE ENGINEERING OF HUMAN PRIMARY T CELLS VIA...

引用

25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021

作者： Hur, Jeongsoo Chung, Aram School of Biomedical Engineering Korea University Korea Republic of Interdisciplinary Program in Precision Public Health Korea University Korea Republic of

ISBN: (纸本)9781733419031

A novel microfluidic approach specifically designed to engineer human primary T-lymphocytes effectively with high scalability while maintaining cell functionality is reported. The system employs a unique cell elongation-restoration phenomenon called "cell stretching," which enables highly effective intracellular delivery of external cargos into cells. Vortical recirculation flows are exerted where cells are hydrodynamically elongated and restored, resulting in effective permeabilization of the cellular membrane. Using the platform, highly efficient (>90%), low-material-cost (6 cells/min) delivery of various cargos into human primary T-cells was achieved, demonstrating the practical utility for chimeric antigen receptor (CAR) T-cell-based cancer immunotherapy. © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.

关键词： T-cells

来源：评论

学校读者我要写书评

暂无评论

Correction: Recent progress in DNA data storage based on high-throughput DNA synthesis

引用

Biomedical engineering letters 2024年第5期14卷 1147-1152页

作者： Seokwoo Jo Haewon Shin Sung-Yune Joe David Baek Chaewon Park Honggu Chun Department of Biomedical Engineering Korea University 466 Hana Science Hall Seoul 02841 Korea. Interdisciplinary Program in Precision Public Health Korea University 466 Hana Science Hall Seoul 02841 Korea.

[This corrects the article DOI: 10.1007/s13534-024-00386-z.].

关键词：

来源：评论

学校读者我要写书评

暂无评论

MICROFLUIDIC CELL SHEARING ENABLES HIGHLY EFFECTIVE MACROMOLECULE INTRACELLULAR DELIVERY 25

MICROFLUIDIC CELL SHEARING ENABLES HIGHLY EFFECTIVE MACROMOL...

引用

25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021

作者： Kwon, Chan Kang, GeoumYoung Chung, Aram School of Biomedical Engineering Korea University Seoul Korea Republic of Interdisciplinary Program in Precision Public Health Korea University Seoul Korea Republic of

ISBN: (纸本)9781733419031

A novel microfluidic cell stretching platform using viscoelastic fluids is presented, enabling highly effective intracellular delivery of external biomolecules into various cell types. The cell suspended in methylcellulose (MC) solution is injected into the platform, where cells rapidly pass through a single constriction with a dimension slightly smaller than the cell diameter. Because of the MC solution, a high shear force is applied to the cells, effectively generating transient cell membrane discontinuities. With this approach, a high delivery efficiency (>97%), high throughput (>106 cells/min) and nearly clogging-free of various macromolecules into different immune cells were demonstrated for cancer immunotherapy applications. © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.

关键词： Cells

来源：评论

学校读者我要写书评

暂无评论

High-Resolution Hydrogen Molecule Detection Utilizing a Nanocandle-Based Optical Sensor 16

High-Resolution Hydrogen Molecule Detection Utilizing a Nano...

引用

16th Pacific Rim Conference on Lasers and Electro-Optics, CLEO-PR 2024

作者： Park, Nu-Ri Kim, Min-Joong Lee, Jongsu Seo, Minah Ryu, Yong-Sang Kim, Myung-Ki KU-KIST Graduate School of Converging Science and Technology Korea University Seoul02841 Korea Republic of Korea Institute of Science and Technology Sensor System Research Center Seoul02792 Korea Republic of Northwestern University Department of Electrical Engineering and Computer Science EvanstonIL60208 United States School of Biomedical Engineering Korea University Seoul02481 Korea Republic of Interdisciplinary Program in Precision Public Health Korea University Seoul02481 Korea Republic of

Our research introduces a novel method for safe hydrogen detection. We've developed an advanced nano-candle sensor, combining Pd with nano-candles, enabling accurate detection of low-concentration hydrogen ( ©... 详细信息

ISBN: (纸本)9798350372076

关键词： Nanoclay

来源：评论

学校读者我要写书评

暂无评论

Experimentation of Integrating Roadmapping and Sci-Fi Prototyping Methods

Experimentation of Integrating Roadmapping and Sci-Fi Protot...

引用

2024 Portland International Conference on Management of engineering and Technology, PICMET 2024

作者： Nishinaka, Miwa Shirahada, Kunio Kishita, Yusuke Miyamoto, Dohjin Osawa, Hirotaka Kiyokawa, Sachiko Takeda, Hideaki The Graduate School of Management Kagawa University Kagawa Takamatsu Japan Ishikawa Nomi Japan The University of Tokyo Department of Precision Engineering Tokyo Japan Communication in Science and Technology Education and Research Program Hokkaido University Sapporo Japan Keio University Faculty of Science and Technology Kanagawa Yokohama Japan Graduate School of Education The University of Tokyo Tokyo Japan National Institute of Informatics Tokyo Japan

ISBN: (纸本)9781890843458

In 2023, we proposed a hypothetical knowledge management framework that incorporates science fiction prototyping (SFP) into the traditional roadmapping (RM) method to make RM more innovative and create a future beyond what we can currently imagine. Our main objective is to create a new organizational knowledge co-creation method for generating innovative ideas by incorporating humanistic factors utilizing SFP into RM. In the current article, we present the exploratory study we conducted to examine the hypothetical framework. Experimental workshops were held in November 2023 to compare the integrated method, in which SFP is applied to RM, with the original RM method. We followed a crossover design in the workshops and analyzed the results qualitatively and quantitatively following the perspectives proposed in the hypothetical framework. The qualitative analysis revealed successful integration regarding diverse and broader perspectives. The quantitative analysis utilizing Wilcoxon signed rank tests showed that the scores of the integrated method were significantly higher than those of RM for variables evaluating the effectiveness of the integration, while not for variables related to participants' feelings and satisfaction with the workshops, and sustainability. These findings indicate that the integration was successful in terms of its effectiveness as a method, while participants' subjective feelings toward the workshops were not different in both methods. As for sustainability, which requires a long-term perspective, no apparent differences were observed in these short-term workshops. © 2024 PICMET.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Visualizing cortical blood perfusion after photothrombotic stroke in vivo by needle-shaped beam optical coherence tomography angiography

引用

PhotoniX 2024年第1期5卷 605-621页

作者： Xiangyu Guo Jingjing Zhao Liqun Sun Varun Gupta Lin Du Komal Sharma Aidan Van Vleck Kaitlyn Liang Liangcai Cao Lingjie Kong Yuanmu Yang Yong Huang Adam de la Zerda Guofan Jin State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing 100084China Department of Structural Biology Stanford University School of MedicineStanford UniversityStanfordCA 94305USA Department of Neurosurgery Stanford University School of MedicineStanford UniversityStanfordCA 94305USA Department of Radiology Stanford University School of MedicineStanford UniversityStanfordCA 94305USA Department of Electrical Engineering and Computer Sciences University of CaliforniaBerkeley 94720USA School of Optics and Photonics Beijing Institute of TechnologyNo.5 South Zhongguancun StreetHaidianBeijing 100081China Biophysics Program Molecular Imaging Programand Bio-X Program at Stanford UniversityStanfordCA 94305USA Chan Zuckerberg Biohub San FranciscoCA 94110USA Institute of Medical Equipment Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China

Optical imaging techniques provide low-cost,non-radiative images with high spatiotemporal resolution,making them advantageous for long-term dynamic observation of blood perfusion in stroke research and other brain studies compared to non-optical ***,high-resolution imaging in optical microscopy fundamentally requires a tight optical focus,and thus a limited depth of field(DOF).Consequently,large-scale,non-stitched,high-resolution images of curved surfaces,like brains,are difficult to acquire without z-axis *** overcome this limitation,we developed a needle-shaped beam optical coherence tomography angiography(NB-OCTA)system,and for the first time,achieved a volumetric resolution of less than 8μm in a non-stitched volume space of 6.4 mm×4 mm×620μm in *** system captures the distribution of blood vessels at 3.4-times larger depths than normal OCTA equipped with a Gaussian beam(GB-OCTA).We then employed NB-OCTA to perform long-term observation of cortical blood perfusion after stroke in vivo,and quantitatively analyzed the vessel area density(VAD)and the diameters of representative vessels in different regions over 10 days,revealing different spatiotemporal dynamics in the acute,sub-acute and chronic phase of post-ischemic *** from our NB-OCTA,we revealed that the recovery process is not only the result of spontaneous reperfusion,but also the formation of new *** study provides visual and mechanistic insights into strokes and helps to deepen our understanding of the spontaneous response of brain after stroke.

关键词： Optical coherence tomography angiography Diffractive optical elements Needle-shaped beam Brain imaging Stroke Cortical blood perfusion

来源：评论

学校读者我要写书评

暂无评论

Cardiac Fibroblast-Mediated ECM Remodeling Regulates Maturation in an in vitro Cardiac Bundle Developmental Model

SSRN

引用

SSRN 2024年

作者： Jang, Yongjun Kang, Myeongjin Kang, Yong Guk Lee, Dongtak Jung, Hyo Gi Yoon, Dae Sung Kim, Jongseong Park, Yongdoo Department of Biomedical Sciences College of Medicine Korea University Seoul Korea Republic of School of Biomedical Engineering Korea University Seoul Korea Republic of Interdisciplinary Program in Precision Public Health Korea University Seoul Korea Republic of

Cardiac fibroblasts play an important role in heart homeostasis, regeneration, and disease by producing extracellular matrix (ECM) proteins and remodeling enzymes. Under normal conditions, fibroblasts exist in a quiescent state and maintain homeostasis, such as tissue structure and ECM turnover. However, if they become activated upon stimuli, such as injury, aging, or mechanical stress, which can lead to disease through excessive cell proliferation and ECM production. In addition to studying fibroblasts in disease progression, their role in cardiac maturation during development and whether the mechanism of cytokine and ECM production is similar to that observed during disease progression is unclear. In this study, we examined the functional and structural maturation of cardiac tissue by modulating fibroblast activity using an in vitro model of cardiac bundle formation. In this model, human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) and human cardiac fibroblasts (CFBs) were co-cultured in a fibrin gel and their morphology, beating characteristics, beating force, and mRNA expression profiles were analyzed. The results indicated that the cardiac bundle model matured structurally and functionally through tissue contraction and collagen deposition by fibroblasts, whereas inhibition of these ECM remodeling reduced maturation. In particular, the expression of second harmonic generation (SHG) and COL1A revealed that while activated fibroblasts induce structural maturation through sustained collagen deposition, excessive collagen accumulation can reduce functional maturation. Our data suggest that collagen type I expression by cardiac fibroblasts is essential for myocardial tissue maintenance and development through ECM remodeling. Furthermore, the regulation of collagen deposition by fibroblast activity is a crucial factor that influences cardiac development and disease progression. © 2024, The Authors. All rights reserved.

关键词： Stem cells

来源：评论

学校读者我要写书评

暂无评论

Biogas production and its utilization in internal combustion engines - A review

引用

Process Safety and Environmental Protection 2024年 186卷 518-539页

作者： Vasan, Vinod Sridharan, Naveen Venkatesh Feroskhan, M. Vaithiyanathan, Sugumaran Subramanian, Balaji Tsai, Pei-Chien Lin, Yuan-Chung Lay, Chyi-How Wang, Chin-Tsan Ponnusamy, Vinoth Kumar Vellore Institute of Technology Chennai600127 India Department of Mechanical Engineering Faculty of Engineering and Technology SRM Institute of Science and Technology Kattankulathur Chennai603203 India Kaohsiung City807 Taiwan Department of Computational Biology Institute of Bioinformatics Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences Tamil Nadu Chennai602105 India Institute of Environmental Engineering National Sun Yat-sen University Kaohsiung804 Taiwan Center for Emerging Contaminants Research National Sun Yat-sen University Kaohsiung804 Taiwan Master's Program of Green Energy Science and Technology Feng Chia University Taichung City407102 Taiwan Department of Mechanical and Electro-Mechanical Engineering National I-Lan University I Lan Taiwan Research Center for Precision Environmental Medicine Kaohsiung Medical University Kaohsiung City807 Taiwan Kaohsiung City807 Taiwan Division of Operation and Maintenance Engineering Luleå University of Technology Luleå Sweden Department of Chemistry National Sun Yat-sen University Kaohsiung804 Taiwan

This review presents the significance and current challenges associated with fossil fuels, highlighting the need for cleaner and more sustainable energy sources. The significant object of the current study is to concentrate on increased interest in utilizing biogas as a viable substitute for traditional fuels, delving into its characteristics, benefits, accessibility, feasibility, and prospects as an environmentally sustainable energy option. The current study extensively analyses the prospect and significance of biogas in mitigating emissions regulations in Internal Combustion Engines (ICEs). This paper provides a comprehensive overview of recent research on incorporating biogas in internal combustion engines, focusing on emission reduction and the corresponding impact on engine performance. The subject matter encompasses a range of facets about biogas, encompassing its origins, chemical composition, purification, enhancement techniques, and requisite engine adjustments to enable the effective utilization of biogas as an alternative fuel. The study also evaluates the performance of biogas-fuelled ICEs based on the results of cross-referencing with contemporary research and investigates peripheral aspects such as additive inclusion to increase biogas capabilities as fuel and potential applications in advanced engine modes of operation. The review identifies research gaps in the domains of biogas processing and utilization in ICEs and acknowledges existing challenges specific to the adoption of biogas as a conventional fuel alternative. Future research directions are also prescribed, further highlighting the importance of transitioning from fossil fuels to meet environmental goals and global energy demands. © 2024 The Institution of Chemical Engineers

关键词： Biogas

来源：评论

学校读者我要写书评

暂无评论

Characterization and application of photocrosslinkable collagen maleate as bioink in extrusion-based 3D bioprinting

引用

Biomaterials Science 2024年第19期12卷 5063-5075页

作者： Chen, Po-Hsun Chen, I-Hsiang Kao, Wei-Hsiang Wu, Song-Yi Tsai, Wei-Bor Department of Chemical Engineering National Taiwan University No. 1 Sec. 4 Roosevelt Rd. Taipei106 Taiwan Program of Green Materials and Precision Devices School of Engineering National Taiwan University No. 1 Sec. 4 Roosevelt Rd. Taipei106 Taiwan Guangdong Victory Co. Ltd. 4F. A11 Guangdong New Light Source Industrial Park Luocun Shishan Town Nanhai District Foshan City528226 China Guangxi Shenguan Collagen Biological Group Company Limited No. 39 Xijiang 4th Rd. Wuzhou China

3D bioprinting, a significant advancement in biofabrication, is renowned for its precision in creating tissue constructs. Collagen, despite being a gold standard biomaterial, faces challenges in bioink formulations due to its unique physicochemical properties. This study introduces a novel, neutral-soluble, photocrosslinkable collagen maleate (ColME) that is ideal for 3D bioprinting. ColME was synthesized by chemically modifying bovine type I collagen with maleic anhydride, achieving a high substitution ratio that shifted the isoelectric point to enhance solubility in physiological pH environments. This modification was confirmed to preserve the collagen's triple-helix structure substantially. Bioprinting parameters for ColME were optimized, focusing on adjustments to the bioink concentration, extrusion pressure, nozzle speed, and temperature. Results demonstrated that lower temperatures and smaller nozzle sizes substantially improved the print quality of grid structures. Additionally, the application of intermittent photo-crosslinking facilitated the development of structurally robust 3D multilayered constructs, enabling the stable fabrication of complex tissues. Cell viability assays showed that encapsulated cells within the ColME matrix maintained high viability after printing. When compared to methacrylated gelatin, ColME exhibited superior mechanical strength, resistance to enzymatic digestion, and overall printability, positioning it as an outstanding bioink for the creation of durable, bioactive 3D tissues. © 2024 The Royal Society of Chemistry.

关键词： Tissue

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：