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检索条件"机构=Present address: Interdisciplinary Program of Biomedical Engineering"
16 条 记 录,以下是1-10 订阅
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GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model
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Translational Neurodegeneration 2024年 第1期13卷 351-355页
作者: Didio Alberto Ortiz Nuria Peregrín Miguel Valencia Rodrigo Vinueza-Gavilanes Elisa Marín-Ordovas Roberto Ferrero María Jesús Nicolás Gloria González-Aseguinolaza Montserrat Arrasate Tomás Aragón DNA and RNA Medicine Program Center for Applied Medical Research(CIMA)University of NavarraPamplonaSpain Biomedical Engineering Program Center for Applied Medical Research(CIMA)University of NavarraPamplonaSpain Institute of Data Science and Artificial Intelligence(DATAI) University of NavarraPamplonaSpain Navarra Institute for Health Research(IdiSNA) PamplonaSpain Neuroimmunology Department Multiple Sclerosis Center of Catalonia(Cemcat)Vall d’Hebron Research Institute(VHIR)BarcelonaSpain School of Medicine University of NavarraPamplonaSpain Brain Lab Biobizkaia Health Research InstituteBarakaldoSpain Present Address:Ikerbasque Basque Foundation for ScienceBilbaoSpain
Main text The disruption of protein folding homeostasis in motoneurons(MNs)and the accumulation of protein aggregates are some of the main molecular hallmarks of amyotrophic lateral sclerosis(ALS).Evidence from sporad... 详细信息
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Machine learning for improved current-density reconstruction from two-dimensional vector magnetic images
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Physical Review Applied 2025年 第3期23卷 034035-034035页
作者: Niko R. Reed Danyal Bhutto Matthew J. Turner Declan M. Daly Sean M. Oliver Jiashen Tang Kevin S. Olsson Nicholas Langellier Mark J.H. Ku Department of Physics University of Maryland College Park Maryland USA Quantum Technology Center University of Maryland College Park Maryland USA Joint Quantum Institute University of Maryland College Park Maryland USA Department of Biomedical Engineering Boston University Boston Massachusetts USA A. A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlestown Massachusetts USA Department of Electrical and Computer Engineering University of Maryland College Park Maryland USA The MITRE Corporation McLean Virginia 22102 USA Intelligence Community Postdoctoral Research Fellowship Program University of Maryland College Park Maryland 20742 USA Department of Physics Harvard University Cambridge Massachusetts USA Present address: VideaHealth Inc. Boston MA. Department of Materials Science and Engineering University of Delaware Newark Delaware 19716 USA Department of Physics and Astronomy University of Delaware Newark Delaware 19716 USA Present address: Northrop Grumman Mission Systems Linthicum Maryland 21090 USA.
The reconstruction of electrical current densities from magnetic field measurements is an important technique with applications in materials science, circuit design, quality control, plasma physics, and biology. Analy... 详细信息
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Theoretical identification of thermostabilizing amino acid mutations for G-protein-coupled receptors
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Biophysical Reviews 2020年 第2期12卷 323-332页
作者: Murata, Takeshi Yasuda, Satoshi Hayashi, Tomohiko Kinoshita, Masahiro Graduate School of Science Chiba University 1-33 Yayoi-cho Inage Chiba 263-8522 Japan Molecular Chirality Research Center Chiba University 1-33 Yayoi-cho Inage Chiba 263-8522 Japan Institute of Advanced Energy Kyoto University Uji Kyoto 611-0011 Japan Present address: Interdisciplinary Program of Biomedical Engineering Assistive Technology and Art and Sports Sciences Faculty of Engineering Niigata University 8050 Ikarashi 2-no-cho Nishi-ku Niigata 950-2181 Japan
Thermostabilization of a membrane proteins, especially G-protein-coupled receptors (GPCRs), is often necessary for biochemical applications and pharmaceutical studies involving structure-based drug design. Here we rev... 详细信息
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Corrigendum to "Mathematical model of modified hybrid pump mechanism for cardiopulmonary resuscitation" [Computer methods and programs in biomedicine 206 (2021) 106106]
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Computer methods and programs in biomedicine 2022年 218卷 106711页
作者: Dong Ah Shin Jung Chan Lee Interdisciplinary Program in Bioengineering Graduate School Seoul National University Seoul 08826 Republic of Korea. Department of Biomedical Engineering College of Medicine and Institute of Medical and Biological Engineering Medical Research Center Seoul National University Seoul 03080 Republic of Korea Institute of BioEngineering Bio-MAX Institute Seoul National University Seoul 08826 Republic of Korea. Electronic address: ljch@snu.ac.kr.
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Corrigendum to "Dual regulatory effects of neferine on amyloid-β and tau aggregation studied by in silico, in vitro, and lab-on-a-chip technology" [Biomed. Pharmacother. 172 (2024) 1-14/116226]
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024年 181卷 117686页
作者: Yunkwon Nam Ritu Prajapati Sujin Kim Soo Jung Shin Da Yeon Cheong Yong Ho Park Hyun Ha Park Danyou Lim Yoojeong Yoon Gyudo Lee Hyun Ah Jung Insu Park Dong-Hyun Kim Jae Sue Choi Minho Moon Department of Biochemistry College of Medicine Konyang University 158 Gwanjeodong-ro Seo-gu Daejeon 35365 Republic of Korea. Department of Food and Life Science Pukyong National University Busan 48513 Republic of Korea. Department of Biochemistry College of Medicine Konyang University 158 Gwanjeodong-ro Seo-gu Daejeon 35365 Republic of Korea Research Institute for Dementia Science Konyang University 158 Gwanjeodong-ro Seo-gu Daejeon 35365 Republic of Korea. Department of Biotechnology and Bioinformatics Korea University Sejong 30019 Republic of Korea Interdisciplinary Graduate Program for Artificial Intelligence Smart Convergence Technology Korea University Sejong 30019 Republic of Korea. Department of Biomedical Engineering Konyang University Daejeon 35365 Republic of Korea. Department of Food Science and Human Nutrition Chonbuk National University Jeonju 54896 Republic of Korea. Department of Biomedical Engineering Konyang University Daejeon 35365 Republic of Korea. Electronic address: insupark@konyang.ac.kr. Departments of Pharmacology and Advanced Translational Medicine School of Medicine Konkuk University Seoul 05029 Republic of Korea. Electronic address: mose79@kku.ac.kr. Department of Food and Life Science Pukyong National University Busan 48513 Republic of Korea. Electronic address: choijs@pknu.ac.kr. Research Institute for Dementia Science Konyang University 158 Gwanjeodong-ro Seo-gu Daejeon 35365 Republic of Korea. Electronic address: hominmoon@konyang.ac.kr.
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scTenifoldXct: A semi-supervised method for predicting cell-cell interactions and mapping cellular communication graphs
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Cell systems 2023年 第4期14卷 302-311.e4页
作者: Yongjian Yang Guanxun Li Yan Zhong Qian Xu Yu-Te Lin Cristhian Roman-Vicharra Robert S Chapkin James J Cai Department of Electrical and Computer Engineering Texas A&M University College Station TX 77843 USA. Department of Statistics Texas A&M University College Station TX 77843 USA. Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of Statistics East China Normal University 3663 North Zhongshan Road Shanghai 200062 China. Department of Veterinary Integrative Biosciences Texas A&M University College Station TX 77843 USA. Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan. Department of Nutrition and the Program in Integrative Nutrition & Complex Diseases Texas A&M University College Station TX 77843 USA. Electronic address: r-chapkin@tamu.edu. Department of Electrical and Computer Engineering Texas A&M University College Station TX 77843 USA Department of Veterinary Integrative Biosciences Texas A&M University College Station TX 77843 USA Interdisciplinary Program of Genetics Texas A&M University College Station TX 77843 USA. Electronic address: jcai@tamu.edu.
We present scTenifoldXct, a semi-supervised computational tool for detecting ligand-receptor (LR)-mediated cell-cell interactions and mapping cellular communication graphs. Our method is based on manifold alignment, u... 详细信息
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Corrigendum to "Variations of oxidative potential of PM2.5 in a medium-sized residential city in South Korea measured using three different chemical assays" [920 (2024) 171053]
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The Science of the total environment 2024年 926卷 172075页
作者: Pyung-Rae Kim Sung-Won Park Young-Ji Han Myong-Hwa Lee Thomas M Holsen Cheol-Heon Jeong Greg Evans Agriculture and Life Sciences Research Institute Kangwon National University Chuncheon Gangwon-do 24341 Republic of Korea. Dept. of Interdisciplinary Graduate Program in Environmental and Biomedical Convergence Kangwon National University Chuncheon Gangwon-do 24341 Republic of Korea. Dept. of Environmental Science Kangwon National University Chuncheon Gangwon-do 24341 Republic of Korea Gangwon particle pollution research and management center Kangwon National University Chuncheon Gangwon-do 24341 Republic of Korea. Electronic address: youngji@kangwon.ac.kr. Gangwon particle pollution research and management center Kangwon National University Chuncheon Gangwon-do 24341 Republic of Korea Dept. of Environmental Engineering Kangwon National University Chuncheon Gangwon-do 24341 Republic of Korea. Dept. of Civil and Environmental Engineering Clarkson University Potsdam NY 13699 USA. Dept. of Chemical Engineering and Applied Chemistry University of Toronto Toronto Ontario MS5 3E5 Canada.
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Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
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Cell 2025年
作者: Xiao Yan David Kuster Priyesh Mohanty Jik Nijssen Karina Pombo-García Jorge Garcia Morato Azamat Rizuan Titus M Franzmann Aleksandra Sergeeva Anh M Ly Feilin Liu Patricia M Passos Leah George Szu-Huan Wang Jayakrishna Shenoy Helen L Danielson Busra Ozguney Alf Honigmann Yuna M Ayala Nicolas L Fawzi Dennis W Dickson Wilfried Rossoll Jeetain Mittal Simon Alberti Anthony A Hyman Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) Dresden 01307 Saxony Germany. Artie McFerrin Department of Chemical Engineering Texas A&M University College Station TX 77843 USA. Department of Neuroscience Mayo Clinic Jacksonville FL 32224 USA. Biotechnology Center (BIOTEC) Center for Molecular and Cellular Bioengineering Technische Universität Dresden Dresden 01307 Saxony Germany. Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) Dresden 01307 Saxony Germany Edward Doisy Department of Biochemistry and Molecular Biology Saint Louis University St. Louis MO 63104 USA. Department of Molecular Biology Cell Biology & Biochemistry Brown University Providence RI 02912 USA. Center for Biomedical Engineering Brown University Providence RI 02912 USA. Artie McFerrin Department of Chemical Engineering Texas A&M University College Station TX 77843 USA Department of Chemistry Texas A&M University College Station TX 77843 USA Interdisciplinary Graduate Program in Genetics and Genomics Texas A&M University College Station TX 77843 USA. Electronic address: jeetain@tamu.edu. Biotechnology Center (BIOTEC) Center for Molecular and Cellular Bioengineering Technische Universität Dresden Dresden 01307 Saxony Germany. Electronic address: simon.alberti@tu-dresden.de. Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) Dresden 01307 Saxony Germany. Electronic address: hyman@mpi-cbg.de.
Cytosolic aggregation of the nuclear protein TAR DNA-binding protein 43 (TDP-43) is associated with many neurodegenerative diseases, but the triggers for TDP-43 aggregation are still debated. Here, we demonstrate that... 详细信息
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A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization
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Molecular cell 2025年 第11期85卷 2128-2146.e15页
作者: Tim M Gemeinhardt Roshan M Regy Tien M Phan Nanu Pal Jyoti Sharma Olga Senkovich Andrea J Mendiola Heather J Ledterman Amy Henrickson Daniel Lopes Utkarsh Kapoor Ashish Bihani Djamouna Sihou Young C Kim David Jeruzalmi Borries Demeler Chongwoo A Kim Jeetain Mittal Nicole J Francis Montreal Clinical Research Institute (IRCM) Montreal QC Canada Division of Experimental Medicine McGill University Montreal QC Canada. Artie McFerrin Department of Chemical Engineering Texas A&M University College Station TX USA. Department of Biochemistry and Molecular Medicine University of Montreal Montreal QC Canada. Montreal Clinical Research Institute (IRCM) Montreal QC Canada. Department of Biochemistry and Molecular Genetics Midwestern University Glendale AZ USA. Department of Chemistry and Biochemistry The University of Lethbridge Lethbridge AB Canada. Department of Chemistry and Biochemistry City College of New York New York NY USA. Department of Chemical and Biomedical Engineering University of Wyoming Laramie WY USA. Center for Materials Physics and Technology Naval Research Laboratory Washington DC USA. Department of Chemistry and Biochemistry City College of New York New York NY USA Ph.D. Program in Biochemistry The Graduate Center of the City University of New York New York NY USA Ph.D. Program in Biology The Graduate Center of the City University of New York New York NY USA Ph.D. Program in Chemistry The Graduate Center of the City University of New York New York NY USA. Department of Chemistry and Biochemistry The University of Lethbridge Lethbridge AB Canada Department of Chemistry and Biochemistry University of Montana Missoula MT USA. Artie McFerrin Department of Chemical Engineering Texas A&M University College Station TX USA Department of Chemistry Texas A&M University College Station TX USA Interdisciplinary Graduate Program in Genetics and Genomics Texas A&M University College Station TX USA. Electronic address: jeetain@tamu.edu. Division of Experimental Medicine McGill University Montreal QC Canada Department of Biochemistry and Molecular Medicine University of Montreal Montreal QC Canada. Electronic address: nicole.francis@ircm.qc.ca.
Biomolecular condensates are increasingly recognized as key regulators of chromatin organization, yet how their formation and properties arise from protein sequences remains incompletely understood. Cross-species comp... 详细信息
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Corrigendum to "Metal-organic frameworks, NH2-MIL-88(Fe), as carriers for ophthalmic delivery of brimonidine" [Acta Biomater. 79 (2018) 344-353]
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Acta biomaterialia 2019年 85卷 321页
作者: Se-Na Kim Chun Gwon Park Beom Kang Huh Seung Ho Lee Chang Hee Min Yun Young Lee Young Kook Kim Ki Ho Park Young Bin Choy Interdisciplinary Program in Bioengineering College of Engineering Seoul National University Seoul 08826 Republic of Korea. Department of Biomedical Engineering SKKU Institute for Convergence Sungkyunkwan University (SKKU) Suwon 16419 Republic of Korea. Institute of Medical & Biological Engineering Medical Research Center Seoul National University Seoul 03080 Republic of Korea. Department of Biomedical Engineering Seoul National University College of Medicine Seoul 03080 Republic of Korea. Department of Ophthalmology Seoul National University Hospital Seoul 03080 Republic of Korea Department of Ophthalmology Seoul National University College of Medicine Seoul 03080 Republic of Korea. Interdisciplinary Program in Bioengineering College of Engineering Seoul National University Seoul 08826 Republic of Korea Institute of Medical & Biological Engineering Medical Research Center Seoul National University Seoul 03080 Republic of Korea Department of Biomedical Engineering Seoul National University College of Medicine Seoul 03080 Republic of Korea. Electronic address: ybchoy@snu.ac.kr.
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