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SSRN 2025年

作者： Liu, Guangzheng Zhu, Xilin Li, Zeyu Zhu, Liqian Chen, Guohong Niu, Yingjie Sun, Hongyan Zuo, Qisheng Song, Jiuzhou Han, Wei Wei, Wanhong Li, Bichun Jin, Kai Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China Yangzhou University Yangzhou225009 China Key Laboratory of Animal Breeding Reproduction and Molecular Design for Jiangsu Province College of Animal Science and Technology Yangzhou University Yangzhou225009 China Institutes of Agricultural Science and Technology Development Yangzhou University Yangzhou225009 China Department of Animal & Avian Sciences University of Maryland College ParkMD United States Jiangsu Institute of Poultry Sciences/ Poultry institute Chinese Academy of Agricultural Sciences Yangzhou225003 China College of Bioscience and Biotechnology Yangzhou University Yangzhou225009 China College of Biotechnology Jiangsu University of Science and Technology Zhenjiang212100 China

The chicken-induced pluripotent stem cells (iPSCs) have been successfully established and exhibit significant potential for the recovery and conservation of endangered avian species. However, the efficiency of induction remains quite limited. To enhance the induction system, a six-factor reprogramming approach incorporating OCT4, SOX2, NANOG, LIN28, KLF4, and C-MYC (OSNLKM) was employed via lentiviral infection, in combination with the small-molecule compound OAC2 and mouse embryonic fibroblast (MEF) feeder layers. The results demonstrated that the six-factor system significantly accelerated the reprogramming process and improved induction efficiency compared to the conventional four-factor system (OCT4, SOX2, NANOG, and LIN28;OSNL). Additionally, the MEF feeder layers were found to be essential for the successful reprogramming of chicken somatic cells. The inclusion of OAC2 further optimized the reprogramming conditions, enabling the successful induction of iPSCs from chicken embryonic fibroblasts (CEFs) and testicular Sertoli cells. Collectively, this study establishes an optimized reprogramming system for chicken somatic cells, enhancing iPSC induction efficiency and expanding the potential applications of iPSC technology in avian conservation and genetic modification. © 2025, The Authors. All rights reserved.

关键词： Animal cell culture

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Erratum to:Multi-stage anisotropic etching of two-dimensional heterostructures

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Nano Research 2022年第7期15卷 6790-6791页

作者： Lin Li Jichen Dong Dechao Geng Menghan Li Wei Fu Feng Ding Wenping Hu Hui Ying Yang Institute of Molecular Plus Tianjin UniversityTianjin 300072China Center for Multidimensional Carbon Materials Institute for Basic Science(IBS)Ulsan 44919Republic of Korea Pillar of Engineering Product Development Singapore University of Technology and DesignSingapore 487372Singapore Tianjin Key Laboratory of Molecular Optoelectronic Sciences Department of ChemistrySchool of ScienceTianjin University and Collaborative Innovation Center of Chemical Science and EngineeringTianjin 300072China Institute of Materials Research and Engineering(IMRE) Agency for ScienceTechnologyand Research(A*STAR)Singapore 138634Singapore Department of Materials Science and Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea

Erratum to Nano Research 2022,15(6):4909−4915 https://***/10.1007/s12274-022-4193-x The affiliation of the author“Feng Ding”was unfortunately mistakenly *** error did not affect any of the content and conclusions from the published *** addition,one funding was unfortunately *** error did not affect any of the content and conclusions from the published paper.

关键词： conclusions anisotropic content

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Block belief propagation algorithm for two-dimensional tensor networks

arXiv

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arXiv 2023年

作者： Guo, Chu Poletti, Dario Arad, Itai Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Department of Physics Synergetic Innovation Center for Quantum Effects and Applications Hunan Normal University Changsha410081 China Science Mathematics and Technology Cluster Singapore University of Technology and Design 8 Somapah Road 487372 Singapore Engineering Product Development Pillar Singapore University of Technology and Design 8 Somapah Road 487372 Singapore Centre for Quantum Technologies National University of Singapore 117543 Singapore MajuLab CNRS-UNS-NUS-NTU International Joint Research Unit UMI 3654 Singapore Faculty of Physics Technion Haifa3200003 Israel

Belief propagation is a well-studied algorithm for approximating local marginals of multivariate probability distribution over complex networks, while tensor network states are powerful tools for quantum and classical many-body problems. Building on a recent connection between the belief propagation algorithm and the problem of tensor network contraction, we propose a block belief propagation algorithm for contracting two-dimensional tensor networks and approximating the ground state of 2D systems. The advantages of our method are three-fold: 1) the same algorithm works for both finite and infinite systems;2) it allows natural and efficient parallelization;3) given its flexibility it would allow to deal with different unit cells. As applications, we use our algorithm to study the 2D Heisenberg and transverse Ising models, and show that the accuracy of the method is on par with state-of-the-art results. Copyright © 2023, The Authors. All rights reserved.

关键词： Tensors

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Influence of Chemistry and Topography on the Wettability of Copper

arXiv

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arXiv 2025年

作者： Lößlein, Sarah Marie Merz, Rolf Rodríguez-Martínez, Yerila Schäfer, Florian Grützmacher, Philipp G. Horwat, David Kopnarski, Michael Mücklich, Frank Chair of Functional Materials Department of Materials Science Saarland University Saarbrücken66123 Germany Institute for Surface and Thin Film Analysis Technische Universität Kaiserslautern Kaiserslautern67663 Germany University of Havana Photovoltaic Research Laboratory Institute of Materials Science and Technology Physics Faculty San Lázaro y L Havana10 400 Cuba Université de Lorraine CNRS IJL NancyF-54000 France Materials Science and Methods Department of Materials Science Saarland University Saarbrücken66123 Germany Institute for Engineering Design and Product Development Tribology Research Group TU Wien Vienna1040 Austria

To understand the complex interplay of topography and surface chemistry in wetting, fundamental studies investigating both parameters are needed. Due to the sensitivity of wetting to miniscule changes in one of the parameters it is imperative to precisely control the experimental approach. A profound understanding of their influence on wetting facilitates a tailored design of surfaces with unique functionality. We present a multi-step study: The influence of surface chemistry is analyzed by determining the adsorption of volatile carbonous species (A) and by sputter deposition of metallic copper and copper oxides on flat copper substrates (B). A precise surface topography is created by laser processing. Isotropic topography is created by ps laser processing (C) and hierarchical anisotropic line patterns are produced by direct laser interference patterning (DLIP) with different pulse durations (D). Our results reveal that the long-term wetting response of polished copper surfaces stabilizes with time despite ongoing accumulation of hydrocarbons and is dominated by this adsorption layer over the oxide state of the substrate (Cu, CuO, Cu2O). The surfaces’ wetting response can be precisely tuned by tailoring the topography via laser processing. The sub-pattern morphology of primary line-like patterns showed great impact on the static contact angle, wetting anisotropy and water adhesion where an increased roughness inside the pattern valleys and a minor roughness on pattern peaks favors air-inclusions, isotropic hydrophobicity, and low water adhesion. Increasing aspect ratio showed to enhance air-inclusions and hydrophobicity despite increased peak roughness while time dependent wetting transitions were observed. Copyright © 2025, The Authors. All rights reserved.

关键词： Copper oxides

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Sequential updating of quantitative requirements for increased flexibility in robust systems design 22

Sequential updating of quantitative requirements for increas...

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22nd International Conference on Engineering design, ICED 2019

作者： Funk, Matthias Jautze, Marcus Strohe, Manfred Zimmermann, Markus BMW Department of Preliminary Design for Vehicle Dynamics Hochschule Landshut University of Applied Sciences Mechanical Engineering Germany Technische Universität München Laboratory for Product Development and Lightweight Design Germany

In early development stages of complex systems, interacting subsystems (including components) are often designed simultaneously by distributed teams with limited information exchange. Distributed development becomes possible by assigning teams independent design goals expressed as quantitative requirements equipped with tolerances to provide flexibility for design: so-called solution-spaces are high-dimensional sets of permissible subsystem properties on which requirements on the system performance are satisfied. Edges of box-shaped solution spaces are permissible intervals serving as decoupled (mutually independent) requirements for subsystem design variables. Unfortunately, decoupling often leads to prohibitively small intervals. In so-called solution-compensation spaces, permissible intervals for early-decision variables are increased by a compensation mechanism using late-decision variables. This paper presents a multi-step development process where groups of design variables successively change role from early-decision to late-decision type in order to maximize flexibility. Applying this to a vehicle chassis design problem demonstrates the effectiveness of the approach. © 2019 design Society. All rights reserved.

关键词： product design

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Exploring the nano-polishing mechanisms of Invar

Research Square

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Research Square 2022年

作者： Wang, Wan Hua, Dongpeng Luo, Dawei Zhou, Qing Eder, Stefan J. Li, Shuo Wang, Zhijun Wang, Haifeng Center of Advanced Lubrication and Seal Materials Northwestern Polytechnical University Shaanxi Xi’an710072 China AC2T research GmbH Viktor-Kaplan-Straße 2/C Wiener Neustadt2700 Austria Institute for Engineering Design and Product Development TU Wien Lehárgasse 6 – Objekt 7 Vienna1060 Austria State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi’an China

With the rapid development of nano-polishing technology, ultra-precise micro-nano components require tighter tolerances for the surface engineering of the Invar alloy. Due to its low hardness and high chemical activity, it is a challenge to reveal the nano-polishing mechanism experimentally. In this work, we studied the effect of polishing parameters on the nano-polishing properties of Invar by molecular dynamics simulation, and experiments were conducted to verify the simulation results. Our findings indicate that higher polishing speed and shallower polishing depth with optimized rolling torque can lead to a reduction of the subsurface damage layer thickness as well as an improvement in polishing efficiency and surface quality. The nano-polishing mechanism is revealed, showing that effective removal occurs only in the plowing regime and the cutting regime, which require sufficient rolling and sliding depths, respectively. Furthermore, an analytic removal theory was developed that excellently describes and predicts the polishing behavior of Invar. This work provides a guideline for improving the polishing precision, surface quality, and material removal efficiency for Invar work pieces. © 2022, CC BY.

关键词： Molecular dynamics

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Overcoming Van der Waals Forces in reconfigurable nanostructures

arXiv

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arXiv 2022年

作者： Zhang, Wang Wang, Hao Tan, Alvin T.L. Ranganath, Anupama Sargur Zhang, Biao Wang, Hongtao Chan, John You En Ruan, Qifeng Liu, Hailong Ha, Son Tung Wang, Dong Ravikumar, Venkat K. Low, Hong Yee Yang, Joel K.W. Engineering Product Development Singapore University of Technology and Design Singapore487372 Singapore Northwestern Polytechnical University 127 West Youyi Road Xi'An710072 China Institute of Materials Research and Engineering Singapore138634 Singapore Robotics Institute State Key Laboratory of Mechanical System and Vibration School of Mechanical Engineering Shanghai Jiao Tong University Shanghai200240 China Advanced Micro Devices Singapore Pte Ltd Singapore Singapore

Reconfigurable metamaterials1-3 require constituent nanostructures to demonstrate switching of shapes with external stimuli. For generality, such nanostructures would touch and stick to other surfaces in one of its configurations. Yet, a longstanding challenge is in overcoming this stiction caused by Van der Waals forces, which impedes shape recovery. Here, we introduce a stiff yet self-recovering material system based on acrylic acid, and tested it in high-aspect ratio structures, where recovery is weak. This designer material has a storage modulus of ~5.2 GPa at room temperature and ~90 MPa in the rubbery state at 150 ℃, an order of magnitude higher than previous reports. A high-resolution resin for two-photon lithography was developed based on this polymer system, enabling 3D printing of nanopillars with diameters of ~400 nm and aspect ratio as high as ~10. Experimentally, we observed self-recovery as collapsed and touching structures overcome stiction to stand back up. We developed a theoretical model to explain the recoverability of these sub-micron structures. Reconfigurable structural colour prints and holograms were demonstrated, indicating potential applications of the material system as a shape memory polymer suitable for sub-micron reconfigurable metamaterials. Copyright © 2022, The Authors. All rights reserved.

关键词： Van der Waals forces

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Flame-Assisted Ultrafast Synthesis of Functionalized Carbon Nanosheets for High-Performance Sodium Storage

SSRN

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SSRN 2022年

作者： Chen, Chen Yan, Dong Lim, Yew Von Liu, Lei Li, Xue Liang Chen, Junjie Li, Tian Chen Zhu, Youyu Cai, Jiangtao Huang, Ying Zhang, Yating Ying Yang, Hui School of Chemistry and Chemical Engineering Northwestern Polytechnical University Shaanxi Xi’an710072 China Pillar of Engineering Product Development Singapore University of Technology and Design 8 Somapah Road Singapore487372 Singapore International Joint Laboratory of New Energy Materials and Devices of Henan Province School of Physics & Electronics Henan University Kaifeng475004 China College of Chemistry and Chemical Engineering Xi’an University of Science and Technology Shaanxi Xi'An710054 China

Traditional methods in preparation of hard carbon (HC) requires special equipment, long reaction times, and large energy consumption, resulting in low throughputs and efficiency. In our contribution, a novel synthesis method is proposed, involving the formation of HC nanosheet within minutes by flame combustion in air, and further introduction of sulfur and nitrogen sources to achieve heteroatom doping. It was confirmed by HRTEM, XPS, EPR, and Raman that HC prepared by flame combustion are rich in defects, pores and heteroatom functional groups. Combined with density functional theory calculation, it is verified that the functionalized hard carbon has stronger Na+ adsorption ability, electron gain ability, and Na+ migration ability. As a result, NS-CNs as sodium-ion battery anodes provide an ultra-high reversible capacity of 542.7 mAh/g at 50 mA/g, and excellent rate performance with reversible capacity of236.4 mAh/g at 2 A/g after 1200 cycles. This work provides a novel and facile strategy to develop novel carbons and gives the deep insights for the further investigation of facile preparation method to develop high-performance carbon anodes for alkali-ion batteries. © 2022, The Authors. All rights reserved.

关键词： Sodium-ion batteries

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Natural and artificial evolution of acetolactate synthase for crop breeding

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The Crop Journal 2025年

作者： Wenbo Pan Yaoyao Zhu Pingdong Li Zhiqiang Li Chunjue Xu Man Jin Xiaoyan Tang Guangdong Provincial Key Laboratory of Biotechnology for Plant Development School of Life Sciences South China Normal University Guangzhou 510631 Guangdong China Shenzhen Institute of Molecular Crop Design Shenzhen 518107 Guangdong China Shenzhen Inspection and Testing Center of Agricultural Product Quality and Safety Shenzhen 518100 Guangdong China

Acetolactate synthase (ALS)-targeting herbicides are among the most widely used weed-control chemicals globally. Mutations in the ALS gene can confer herbicide resistance in crops, thereby allowing selective elimination of weeds without harming crops. Herbicide-resistant ALS alleles were initially discovered in weeds and subsequently developed through artificial mutagenesis techniques. With the advancement of CRISPR/Cas technology, various genome-editing tools are now available to introduce these resistant alleles, as well as novel variants, into diverse crop species. Moreover, emerging methodologies, such as directed evolution, enable the generation and screening of large populations of random ALS mutants. Consequently, ALS has become one of the most extensively targeted genes in plant gene evolution. This paper provides a comprehensive overview of both conventional and recently developed strategies for ALS evolution, with particular emphasis on CRISPR/Cas-based genome editing and directed evolution. Future perspectives on technological application are also discussed. By advancing our understanding of herbicide-resistant ALS allele development for crop improvement, these methodologies may also pave the way for their application to the evolution of other agronomically important genes.

关键词： Herbicide resistance Acetolactate synthase Genome editing Directed evolution

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Ti 3 C 2 T x MXene modified alkyl imidazolium ionic liquid-stearic acid composite materials as a potential lubricant for steel/steel contact

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Wear 2025年 578-579卷

作者： Xudong Sui Junming Liu Gaiqing Zhao Xiaobo Wang Yongqin Han Carsten Gachot Institute for Engineering Design and Product Development Research Unit Tribology TU Wien Vienna 1060 Austria State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical Physics Chinese Academy of Sciences Lanzhou 730000 China School of Materials Science and Engineering Shandong University of Science and Technology Qingdao 266590 China

This study proposes a simplified method for preparing a novel BMImPF 6 -stearic acid-Ti 3 C 2 T x ternary composite lubricant through heating, ultrasonication, and three-roll milling. Rheological tests indicate that the resulting composite lubricant exhibits typical non-Newtonian fluid behavior. Friction and wear tests reveal that the BMImPF 6 -stearic acid composite lubricant with 0.3 wt.-% MXene exhibits the best tribological performance, with a friction coefficient of approximately 0.06 and a wear rate as low as 1.32 × 10 −9 mm 3 /Nm, highlighting its potential as a lubricant for steel/steel contact. The study demonstrates that the endothermic phase change properties of stearic acid regulate the temperature at the friction interface, while BMImPF 6 ensures the formation of an effective tribochemical film, and MXene provides additional repair protection.

关键词： MXene Ionic liquid Rheological property Stearic acid Friction and wear

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