检索结果-内蒙古大学图书馆

Accelerated radiotherapy in patients over sixty years old after mastectomy: Acute and one-year physician-Assessed toxicity and health-related quality of life

引用

Breast Disease 2022年第1期41卷 261-266页

作者： Vakaet, Vincent Van Hulle, Hans Quataert, Viktor Deseyne, Pieter Schoepen, Max Paelinck, Leen Post, Giselle Van Greveling, Annick Speleers, Bruno Mareel, Marc De Neve, Wilfried Monten, Chris Veldeman, Liv Department of Human Structure and Repair Ghent University Ghent Belgium Department of Radiation Oncology Ghent University Hospital C. Heymanslaan 10 Ghent 9000 Belgium Department of Industrial Systems Engineering and Product Design Kortrijk Belgium

INTRODUCTION: Postmastectomy radiotherapy reduces the risk of locoregional recurrence in breast cancer patients. The first results on accelerated radiotherapy in five fractions after breast conserving surgery are promising. The data on postmastectomy radiotherapy in five or six fractions is limited. We now present the data on acute and one-year toxicity and health related quality of life (HRQoL) after postmastectomy radiotherapy in patients of sixty years or older. METHODOLOGY: 119 patients received five fractions of 5.7 Gy to the chest wall and five fractions of 5.4 Gy to the lymph nodes over ten to twelve days. Physician-Assessed toxicity were scored using the Common Terminology Criteria for Adverse Events version 4.03 toxicity scoring system and the LENT-SOMA scale. Fatigue was measured by the Multidimensional Fatigue Inventory (MFI-206). HRQoL was assessed using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire the breast cancer specific module and the BREAST-Q questionnaire. RESULTS: Fatigue and edema were the most frequently observed physician-Assessed toxicities. One year after radiotherapy only 12.9% experienced a clinically important deterioration in chest wall symptoms and in 22.9% of the patients were improved. Future perspective at one year after radiotherapy was improved in 40.0% of the patients. Patient-reported fatigue showed the greatest improvement. CONCLUSION: Accelerated radiotherapy should be considered to minimize the burden of breast cancer treatment, especially in older patients. © 2022-IOS Press. All rights reserved.

关键词： Radiation oncology Radiation side effects Radiation therapy techniques

来源：评论

学校读者我要写书评

暂无评论

Identification and prediction of standard times in machining for precision steel tubes through the usage of data analytics 33

Identification and prediction of standard times in machining...

引用

33rd CIRP design Conference

作者： Weller, Julian Roesmann, Daniel Eggert, Sönke von Enzberg, Sebastian Gräßler, Iris Dumitrescu, Roman Fraunhofer Institute for Mechatronic Systems Design Zukunftsmeile 1 Paderborn33102 Germany Product Creation Heinz Nixdorf Institute Fürstenallee 11 Paderborn33102 Germany BENTELER Steel/Tube Residenzstraße 1 Paderborn33104 Germany Advanced Systems Engineering Heinz Nixdorf Institute Fürstenallee 11 Paderborn33102 Germany

An approach to predict standard times for upcoming individual customer orders based on historical production orders is developed. The approach follows the CRISP-DM model with regard to the steps data preparation, modeling and evaluation. A precision steel tube straightening machine is provided as a validation example. Furthermore, the paper focuses on how the standard time prediction approach can be successfully integrated into the IT infrastructure of a production focused company. Especially data availability and accessibility in enterprise resource planning systems are discussed. The presented approach offers users the value of more precise scheduling in production than established approaches. © 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (https://***/licenses/by-nc-nd/4.0)

关键词： Data Analytics

来源：评论

学校读者我要写书评

暂无评论

Towards Personalized 3D Bioprinting: Leveraging Cluster-based Machine Learning for Mass Customization

Towards Personalized 3D Bioprinting: Leveraging Cluster-base...

引用

IISE Annual Conference and Expo 2024

作者： Limon, Shah M. Sarah, Rokeya Rahman, Mahmudur Habib, M.D. Ahasan Physics and Engineering Department Slippery Rock University of Pennsylvania Slippery RockPA16057 United States Sustainable Product Design and Architecture Department Keene State College KeeneNH03435 United States Industrial Manufacturing and Systems Engineering Department The University of Texas at Arlington ArlingtonTX76019 United States Manufacturing and Mechanical Engineering Technology Department Rochester Institute of Technology RochesterNY14624 United States

ISBN: (纸本)9781713877851

3D bioprinting emerged as a potential technology for biomedical and tissue engineering. Mass customization in terms of material selection, cell types, fabrication techniques, along with shortened fabrication time made 3D bioprinting very attractive in medical-related applications. However, the bioprinting process remains challenging in two folds: finding optimal process parameters for desired mechanical properties of scaffolds and obtaining cell type-based microenvironment into fabricated scaffolds. Getting both the personalized mechanical properties and microenvironment of 3D bioprinted scaffolds simultaneously sometimes even inversely related. In this work, we adopted the clustering-based machine learning technique to understand both the mechanical and microenvironment of scaffolds. K-means clustering would apply to obtain an optimal number of clusters for the bioprinting experimental dataset. Each cluster obtained from cluster-based machine learning technique will be analyzed and rated based on the patterns toward bioprinting of scaffold ensuring user defined mechanical properties and personalized microenvironment. This new approach would help 3D bioprinting practitioners to address the dual challenge of achieving desired properties and microenvironment in printed scaffolds. © IISE Annual Conference and Expo *** rights reserved.

关键词： Fabrication

来源：评论

学校读者我要写书评

暂无评论

The role of equipment flexibility in Overall Equipment Effectiveness (OEE)-driven process improvement 55

The role of equipment flexibility in Overall Equipment Effec...

引用

55th CIRP Conference on Manufacturing systems, CIRP CMS 2022

作者： Van De Ginste, Lauren Aghezzaf, El-Houssaine Cottyn, Johannes Department of Industrial Systems Engineering and Product Design Ghent University Technologiepark 46 Zwijnaarde Gent9052 Belgium Flanders Make vzw Sint-Martens-Latemlaan 2B Kortrijk8500 Belgium

In manufacturing and assembly operations, Overall Equipment Effectiveness (OEE) is a frequently used quantitative metric for measuring the overall productivity of a single machine, cell or an integrated manufacturing system. However, it does neglect and typically even penalizes flexibility capabilities. Today's customer needs for highly customized products put these productivity-based measurements more and more under pressure. Frequent product changes on assembly workstations typically result in lower availability through more set-up, more performance losses due to slower cycles and the learning-forgetting effect of operators, and start-up defects resulting in more frequent quality issues. A contradiction arises: in modern production and assembly this flexibility becomes more and more important as an enabler for the mass customization paradigm, but is difficult to incorporate in (or put in relation to) an OEE figure or trend and conflicts with the OEE-driven process improvement strategies. Consequently, it can be argued that flexibility capabilities should be embedded in the equipment effectiveness calculation. Modern manufacturing and assembly cells should have a high equipment effectiveness through a high product mobility with a stable and uniform productivity across the complete range of products. This paper first highlights the importance of flexibility in the measurement of equipment effectiveness to facilitate the mass customization paradigm and to try to continuously improve towards a resilient manufacturing system. Next, the heuristic measurement framework for the Flexibility-included Overall Equipment Effectiveness (OEEFlex) metric is introduced, based on three core indicators: mobility, uniformity and range. The three factors are introduced and described. Links to current OEE measurement frameworks are made. The approach towards the new metric starts from a long list of losses and variables and possible calculation methods for the indicator values. Future

关键词： Assembly Workstation Flexibility Equipment Effectiveness Manufacturing Flexibility Mass Customization Process Improvement Resilient Manufacturing systems

来源：评论

学校读者我要写书评

暂无评论

Towards a Process Model to Enable Domain Experts to Become Citizen Data Scientists for Industrial Applications

Towards a Process Model to Enable Domain Experts to Become C...

引用

Industrial Cyber-Physical systems (ICPS)

作者： Silke Merkelbach Sebastian Von Enzberg Arno Kü hn Roman Dumitrescu Research Department Product Engineering Fraunhofer Institute for Mechatronic Systems Design PaderbornGermany

It is often a problem to combine domain knowledge and data science knowledge in applications of industrial data analytics. Data scientists usually spend a lot of time to understand the domain to develop an application while domain experts lack the skills to interpret results of underlying mathematical models. This leads to difficulties when adapting to changes, handling issues and transfer to similar scenarios, and thus to a lack of acceptance of data analytics applications in industrial companies. Based on the Cross Industry Standard Process for Data Mining (CRISP-DM), we propose a novel process model which integrates training of domain experts to enable them to become citizen data scientists to independently develop and implement data analytics applications. We qualitatively evaluated our process model on a storage location assignment problem in the warehouse of a manufacturer of high-end domestic appliances.

关键词： Training Adaptation models Home appliances Conferences Data science Data models Mathematical models

来源：评论

学校读者我要写书评

暂无评论

design SPACE OPTIMIZATION FOR SENSOR-INTEGRATION IN STANDARDIZED MACHINE ELEMENTS

DESIGN SPACE OPTIMIZATION FOR SENSOR-INTEGRATION IN STANDARD...

引用

ASME 2024 International Mechanical engineering Congress and Exposition, IMECE 2024

作者： Peters, Julian Menning, Johannes D.M. Ewert, Arthur Prokopchuk, Artem Breimann, Richard Herbst, Felix Riehl, David Döllken, Markus Vorrath, E.-F. Markus Wallmersperger, Thomas Schlecht, Berthold Kirchner, Eckhard Kupnik, Mario Hofmann, Klaus Matthiesen, Sven Institute of Product Engineering Karlsruhe Institute of Technology Germany Institute of Solid Mechanics Technische Universität Dresden Germany Institute of Machine Elements and Machine Design Technische Universität Dresden Germany Institute of Semiconductors and Microsystems Technische Universität Dresden Germany Institute for product development and machine elements Technical University of Darmstadt Germany Measurement and Sensor Technology Group Technical University of Darmstadt Germany Integrated Electronic Systems Lab Technical University of Darmstadt Germany

ISBN: (纸本)9780791888599

In industrial digitization, data-driven analysis like condition monitoring and predictive maintenance relies on extensive measurement data. However, there’s often a lack of data on machine or system states. Sensor-integrating machine elements (SiME) can address this gap due to their widespread use, standardization, and in-situ measurement capability. Yet, integrating sensors typically compromises mechanical function. To ensure broad usability and retrofitting, maintaining mechanical functions to a defined degree is crucial. General procedures for systematically finding optimal design space solutions are lacking. In prior work, a procedure was developed for multi-axial force sensor integration into M20 bolts. This contribution demonstrates the procedure’s applicability to (1) M12 bolts for uni-axial force measurements using strain gauges, and (2) jaw couplings for torque measurement using capacitive sensors. Results indicate the procedure’s efficacy in both cases, yielding viable design space parameters. However, constructing an optimization function for jaw couplings in the final step was not feasible, as both mechanical and sensory function fulfillment indices pointed in the same direction. © 2024 by ASME.

关键词： Bolts

来源：评论

学校读者我要写书评

暂无评论

Enhancing the sustainability and energy conservation in heritage buildings:The case of Nottingham Playhouse

引用

Frontiers of Architectural Research 2022年第1期11卷 142-160页

作者： Amin Al-Habaibeh Allan Hawas Lama Hamadeh Benachir Medjdoub Julian Marsh Arijit Sen Product Innovation Centre School of ArchitectureDesign and the Built EnvironmentNottingham Trent UniversityNottinghamUK Future Energy Center(FEC) School of Business Society and EngineeringDepartment of Civil Engineering and Energy SystemsMälardalen UniversityVästeråsSweden Department of Architecture and Planning Sheffield Hallam UniversitySheffieldUK

Today,there is a growing interest in developing energy efficient buildings since it is estimated that buildings account for about 40%of the total primary energy consumption in the *** relation to existing buildings,energy efficiency retrofits have become an important opportunity to upgrade the energy performance of commercial,public and residential buildings that may reduce the energy consumption,demand and *** this paper we cover the energy efficiency deep retrofit process that has been carried out for Nottingham Playhouse theatre building for the aim of enhancing its environmental performance and analysing the energy efficiency gained after implementing certain proposed *** is a nationally protected historic building,listed as Grade II*on The National Heritage List for England(NHLE).The building has had insulation enhancement,doors modifications,solar energy installations,energy-saving lights,in addition to improved heating and air conditioning *** paper presents a novel methodology;and its results indicate significant improvements in the building’s energy performance which is demonstrated using infrared thermographic images and data logger sensors where significant energy savings to the building’s thermal performance are *** energy saving measures have been completed while maintaining the heritage building’s general appearance and architectural features,which have received a Commendation Certificate from The Nottingham Civic Society for this achievement.

关键词： Deep retrofitting Energy Buildings Insulation Heritage buildings

来源：评论

学校读者我要写书评

暂无评论

Leveraging reconfigurable micro-resonator soliton crystals for Intensity-Modulated Direct Detection Data Transmission

arXiv

引用

arXiv 2024年

作者： Chia, X.X. Ong, K.Y.K. Aadhi, A. Chen, G.F.R. Choi, J.W. Sohn, B.-U. Chowdury, A. Tan, D.T.H. Photonics Devices and Systems Group Engineering Product Development The Singapore University of Technology and Design 8 Somapah Road Singapore487372 Singapore 2 Fusionopolis Way Singapore138634 Singapore

The perennial demand for highly efficient short-haul communications is evidenced by a sustained explosion of growth in data center infrastructure that is predicted to continue for the foreseeable future. In these relatively compact networks, cost-sensitivity is of particular importance, which limits options to direct detection schemes that are more cost efficient than their coherent counterparts. Since their initial demonstration, multi-soliton states in optical microresonators have been observed to manifest in self-organised ensembles where soliton pulses are equally spaced around the resonators. In the spectral domain, these states – dubbed soliton crystals (SCs) – result in significant enhancements to individual comb lines depending on the crystal state, making them well suited towards intensity-modulated direct detection (IMDD) schemes. In this work, we experimentally demonstrate adiabatic, deterministic access to lower-order soliton crystal states using an auxiliary-assisted cavity pumping method, attaining up to 19.6 dB enhancement of the comb lines in the 7-SC configuration compared to the single-soliton state. Seven comb lines of each 46 Gbaud/s pulse amplitude modulation 4 (PAM4) is transmitted over 4km of fiber in comb lines across the C-band with bit-error-rates (BER) as low as 5E-5. Our demonstration shows the promising way of using soliton crystal states as future integrated sources for highly stable Terabaud/s datacenter communications. Copyright © 2024, The Authors. All rights reserved.

关键词： Microresonators

来源：评论

学校读者我要写书评

暂无评论

Towards Automated Hesitation Detection During Support-System Enhanced Industrial Assembly

Towards Automated Hesitation Detection During Support-System...

引用

Virtual Reality (ICVR), IEEE International Conference on

作者： Jamil Joundi Jonas De Bruyne Aleksandra Zheleva Wouter Durnez Jelle Saldien Klaas Bombeke Department of Industrial Systems Engineering and Product Design Imec-Mict-UGent Ghent University Ghent Belgium Department of Communication Sciences Imec-Mict-UGent Ghent University Ghent Belgium

ISBN: (数字)9798350364231

ISBN: (纸本)9798350364248

Modern factories have to accommodate high flexibility, extreme customization and short product life cycles in a cost-effective way. This requires that the operators are provided with sufficient system support to aid their decision-making and hesitation. To investigate how the level of support can affect the operators’ behavior, the current study immersed 27 participants in a virtual reality factory where they were asked to complete three different assemblies with varying levels of system support (low, medium, or high). The support was provided by a collaborative robot (cobot). The participants’ experience was measured via a subjective marker of difficulty and an objective eye-tracking feature (gaze switches). The results showed that when the level of cobot support was low, participants found the assembly step more difficult and were gazing at the instruction screen more often compared to the medium and high support conditions. This suggests that the number of times operators look back at the instruction screen during a step could be a promising marker to automatically detect hesitation behavior in instruction-based assemblies. This study, therefore, presents the initial effort toward validating a behavioral marker of hesitation within this context.

关键词： Atmospheric measurements Current measurement Decision making Collaborative robots Virtual reality Gaze tracking Particle measurements production facilities systems support Assembly

来源：评论

学校读者我要写书评

暂无评论

Mobility Data Mining: the Maritime Use Case

Mobility Data Mining: the Maritime Use Case

引用

IEEE Metrology for Aerospace

作者： Alexandros Troupiotis-Kapeliaris Dimitris Zissis Sean Kohlbrenner Christos Kastrisios Department of Product and Systems Design Engineering Intelligent Transportation Systems Lab (Smart MOVE) University of the Aegean Syros Greece Center for Coastal & Ocean Mapping / Joint Hydrographic Center University of New Hampshire Durham NH USA

ISBN: (数字)9798350385045

ISBN: (纸本)9798350385052

Maritime mobility monitoring can be achieved through remote sensing and self-reporting systems, which produce large datasets enabling the extraction of valuable information on global shipping trends. This extraction can be defined as a data mining task of transforming huge amounts of geospatial data, into a descriptive and compact data model, that can then be used for identifying the underlying relationships or patterns. In this work, we present a brief overview of mobility data mining as applied to the maritime use case. We highlight its unique aspects, identify six major data mining tasks, discuss indicative approaches found in literature, and address some challenges for future work.

关键词： Conferences Metrology Market research Data models Geospatial analysis Data mining Task analysis

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：