The radiation mechanism underlying the prompt emission remains unresolved and can be resolved using a systematic and uniform time-resolved spectro-polarimetric study. In this paper, we investigated the spectral, tempo...
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Scholars have indicated the importance of providing guidance and support for individual learners. In the past decades, most studies have developed adaptivelearning systems to address this issue mainly based on stude...
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Massive infrared dark clouds (IRDCs) are considered to host theearliest stages of high-mass star formation. In particular, 70 μm dark IRDCs are the colder and more quiescent clouds. At a scale of about 5000 au using...
The Black Holeexplorer (BHeX) is a next-generation space very long baseline interferometry (VLBI) mission concept that will extend the ground-based millimeter/submillimeter arrays into space. The mission, closely ali...
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Fragmentation during theearly stages of high-mass star formation is crucial for understanding the formation of high-mass clusters. We investigated fragmentation within 39 high-mass star-forming clumps as part of the ...
Massive infrared dark clouds (IRDCs) are considered to host theearliest stages of high-mass star formation. In particular, 70 µm dark IRDCs are the colder and more quiescent clouds. At a scale of about 5000 au u...
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We present 850 µm thermal dust polarization observations with a resolution of 14.4′′(∼ 0.13 pc) towards an infrared dark cloud G16.96+0.27 using JCMT/POL-2. The average magnetic field orientation, which roughl...
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We present 850 μm imaging of the XMM-LSS field observed for 170 hours as part of the James Clerk Maxwell Telescope SCUBA-2 LargeeXtragalactic Survey (S2LXS). S2LXS XMM-LSS maps an area of 9 deg2, reaching a moderate...
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Background: Pruritus is the most common initial symptom reported by patients with dermatomyositis (DM) and polymyositis (PM). However, there is limited data regarding the impact of pruritus on cancer and mortality in ...
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Background: Pruritus is the most common initial symptom reported by patients with dermatomyositis (DM) and polymyositis (PM). However, there is limited data regarding the impact of pruritus on cancer and mortality in patients with DM and PM. In this study, we aimed to investigate how pruritus is associated with cancer and mortality in patients with DM and PM. Methods: This nationwide, population-based retrospective cohort study included adult DM and PM patients from taiwan’s national Health Insurance Research Database between 2005 and 2022. Sex- and age-matched pruritic patients, identified by over 6 weeks of antipruritic medication use, and nonpruritic patients were analyzed. The primary outcome was cancer occurrence or all-cause mortality. The association between pruritus and these outcomes was estimated using Cox proportional hazards models. Results: Among 919 matched pairs of pruritic and nonpruritic patients, cancer was observed in 19.96% in the long-term pruritic group (LPG), 14.63% in the short-term pruritic group (SPG), and 10.34% in the non-pruritic group (NPG) ( p < 0.0001). All-cause mortality was documented as 30.37% in the LPG, 29.69% in the SPG, and 37.76% in the NPG ( p < 0.0001). After adjusting for sex, age, and other comorbidities, pruritus was associated with an increased risk of cancer (hazard ratio (HR) 1.708, 95% confidence interval (CI) 1.229–2.374) and a lower risk of all-cause mortality (HR 0.483, 95% CI 0.409–0.569). Conclusion: This population-based study revealed that pruritus appeared to be associated with increased risks of cancer and decreased all-cause mortality. Thus, pruritus may serve as a pragmatic factor for risk stratification and tailored treatment strategies in DM and PM. Cancer screening, particularly for nasopharyngeal and breast cancers in east Asian populations, is recommended for patients with DM or PM, especially those presenting with pruritus. Meanwhile, patients without pruritus may require vigilant management for pote
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