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24-Dehydrohippuristanol, a cytotoxic spiroketal steroid from Isis hippuris

Tetrahedron Letters 2023年 123卷

作者： Yi-Qi Huang Amina M Illias Po-Jen Chen Su-Ying Chien Yueh-Hsiung Kuo Chou-Yuan Ko Chun-Feng Chang Zhi-Hong Wen Tsong-Long Hwang Ping-Jyun Sung Graduate Institute of Marine Biology National Dong Hwa University Pingtung 944401 Taiwan National Museum of Marine Biology and Aquarium Pingtung 944401 Taiwan Department of Anesthesiology Chang Gung Memorial Hospital Taoyuan 333423 Taiwan Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University Taoyuan 333323 Taiwan Clinical Immunology Laboratory Department of Medical Research E-Da Hospital I-Shou University Kaohsiung 824005 Taiwan Instrumentation Center National Taiwan University Taipei 106319 Taiwan Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources China Medical University Taichung 404333 Taiwan Department of Medical Laboratory Science and Biotechnology Asia University Taichung 413305 Taiwan Chinese Medical Research Center China Medical University Taichung 404333 Taiwan Division of Gastroenterology Department of Internal Medicine Kaohsiung Armed Forces General Hospital Kaohsiung 802301 Taiwan Institute of Medical Science and Biotechnology National Sun Yat-sen University Kaohsiung 804201 Taiwan Division of Urology Department of Surgery Kaohsiung Armed Forces General Hospital Kaohsiung 802301 Taiwan Department of Marine Biotechnology and Resources National Sun Yat-sen University Kaohsiung 804201 Taiwan Research Center for Chinese Herbal Medicine Graduate Institute of Healthy Industry Technology College of Human Ecology Chang Gung University of Science and Technology Taoyuan 333324 Taiwan Graduate Institute of Natural Products College of Medicine Chang Gung University Taoyuan 333323 Taiwan Department of Chemical Engineering Ming Chi University of Technology New Taipei City 243303 Taiwan Chinese Medicine Research and Development Center China Medical University Hospital Taichung 404394 Taiwan Graduate Institute of Natural Products Kaohsiung Medical University Kaohsiung 807378 Taiwan Program in Pharmaceutical Biotechnology Fu Jen Catholic University New Taipei City 242062 Taiwan

Chemical screening of a Formosan sea bamboo octocoral Isis hippuris have led to the isolation of nine spiroketal steroids, including a new metabolite, 24-dehydrohippuristanol ( 1 ), a new natural product, hippuristanol 11-one ( 2 ), as well as seven known analogs, hippuristanol ( 3 ), 22- epi -hippuristanol ( 4 ), hippurin-1 ( 5 ), 22- epi -hippurin-1 ( 6 ), 3-acetyl-22- epi -hippurin-1 ( 7 ), 3α-acetoxy-11β-hydroxy-24-methyl-22,25-epoxy-5α-furostan-18,20β-lactone ( 8 ) and (22 S )-3α-acetoxy-11β,18α-dihydroxy-24-methyl-18,20β;22,25-diepoxy-5α-furostane ( 9 ). The structures of steroids 1 – 9 were corroborated by 2D NMR experiments and comparison with literature data. The configurations of steroids 3 , 4 , 6 and 9 , obtained in previous studies, were reported for the first time in this study by single-crystal X-ray diffraction analysis. Steroid 1 exhibited cytotoxic effects against DLD-1 and LoVo cancer cells with IC 50 values of 5.54 and 6.89 μM, respectively.

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Corrigendum to “24-Dehydrohippuristanol, a cytotoxic spiroketal steroid from Isis hippuris ”[Tetrahedron Lett. 123 (2023) 154540]

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Tetrahedron Letters 2023年 124卷

作者： Yi-Qi Huang Amina M. Illias Po-Jen Chen Su-Ying Chien Yueh-Hsiung Kuo Chou-Yuan Ko Chun-Feng Chang Zhi-Hong Wen Tsong-Long Hwang Ping-Jyun Sung Graduate Institute of Marine Biology National Dong Hwa University Pingtung 944401 Taiwan National Museum of Marine Biology and Aquarium Pingtung 944401 Taiwan Department of Anesthesiology Chang Gung Memorial Hospital Taoyuan 333423 Taiwan Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University Taoyuan 333323 Taiwan Clinical Immunology Laboratory Department of Medical Research E-Da Hospital I-Shou University Kaohsiung 824005 Taiwan Instrumentation Center National Taiwan University Taipei 106319 Taiwan Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources China Medical University Taichung 404333 Taiwan Department of Medical Laboratory Science and Biotechnology Asia University Taichung 413305 Taiwan Chinese Medical Research Center China Medical University Taichung 404333 Taiwan Division of Gastroenterology Department of Internal Medicine Kaohsiung Armed Forces General Hospital Kaohsiung 802301 Taiwan Institute of Medical Science and Biotechnology National Sun Yat-sen University Kaohsiung 804201 Taiwan Division of Urology Department of Surgery Kaohsiung Armed Forces General Hospital Kaohsiung 802301 Taiwan Department of Marine Biotechnology and Resources National Sun Yat-sen University Kaohsiung 804201 Taiwan Research Center for Chinese Herbal Medicine Graduate Institute of Healthy Industry Technology College of Human Ecology Chang Gung University of Science and Technology Taoyuan 333324 Taiwan Graduate Institute of Natural Products College of Medicine Chang Gung University Taoyuan 333323 Taiwan Department of Chemical Engineering Ming Chi University of Technology New Taipei City 243303 Taiwan Chinese Medicine Research and Development Center China Medical University Hospital Taichung 404394 Taiwan Graduate Institute of Natural Products Kaohsiung Medical University Kaohsiung 807378 Taiwan Program in Pharmaceutical Biotechnology Fu Jen Catholic University New Taipei City 242062 Taiwan

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The ALCHeMI atlas: principal component analysis reveals starburst evolution in NGC 253

arXiv

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arXiv 2024年

作者： Harada, Nanase Meier, David S. Martín, Sergio Muller, Sebastien Sakamoto, Kazushi Saito, Toshiki Gorski, Mark D. Henkel, Christian Tanaka, Kunihiko Mangum, Jeffrey G. Aalto, Susanne Aladro, Rebeca Bouvier, Mathilde Colzi, Laura emig, Kimberly L. Herrero-Illana, Rubén Huang, Ko-Yun Kohno, Kotaro König, Sabine Nakanishi, Kouichiro Nishimura, Yuri Takano, Shuro Rivilla, Víctor M. Viti, Serena Watanabe, Yoshimasa van der Werf, Paul P. Yoshimura, Yuki National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Institute of Astronomy and Astrophysics Academia Sinica 11F of AS/NTU Astronomy-Mathematics Building No.1 Sec. 4 Roosevelt Rd Taipei10617 Taiwan Astronomical Science Program Graduate Institute for Advanced Studies SOKENDAI 2-21-1 Osawa Mitaka Tokyo181-1855 Japan New Mexico Institute of Mining and Technology 801 Leroy Place SocorroNM87801 United States National Radio Astronomy Observatory PO Box O 1003 Lopezville Road SocorroNM87801 United States European Southern Observatory Alonso de Córdova 3107 Vitacura Santiago763-0355 Chile Joint ALMA Observatory Alonso de Córdova 3107 Vitacura Santiago763-0355 Chile Department of Space Earth and Environment Chalmers University of Technology Onsala Space Observatory OnsalaSE-439 92 Sweden Department of Physics and Astronomy Northwestern University EvanstonIL60208 United States Max-Planck-Institut für Radioastronomie Auf dem Hügel 69 Bonn53121 Germany Astronomy Department Faculty of Science King Abdulaziz University P. O. Box 80203 Jeddah21589 Saudi Arabia Department of Physics Faculty of Science and Technology Keio University 3-14-1 Hiyoshi Kanagawa Yokohama223-8522 Japan National Radio Astronomy Observatory 520 Edgemont Road CharlottesvilleVA22903-2475 United States Department of Space Earth and Environment Chalmers University of Technology GöteborgSE-412 96 Sweden Leiden Observatory Leiden University P.O. Box 9513 Leiden2300 RA Netherlands CSIC-INTA Ctra. de Ajalvir Km. 4 Torrejón de Ardoz Madrid28850 Spain Campus UAB Carrer de Magrans BarcelonaE-08193 Spain Institute of Astronomy Graduate School of Science The University of Tokyo 2-21-1 Osawa Mitaka Tokyo181-0015 Japan Department of Astronomy The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan ALMA Project National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Department of Physic

Molecular lines are powerful diagnostics of the physical and chemical properties of the interstellar medium (ISM). These ISM properties, which affect future star formation, are expected to differ in starburst galaxies from those of more quiescent galaxies. We investigate the ISM properties in the central molecular zone of the nearby starburst galaxy NGC 253 using the ultra-wide millimeter spectral scan survey from the ALMA Large program ALCHeMI. We present an atlas of velocity-integrated images at a 1′′. 6 resolution of 148 unblended transitions from 44 species, including the first extragalactic detection of HCNH+ and the first interferometric images of C3H+, NO, HCS+. We conduct a principal component analysis (PCA) on these images to extract correlated chemical species and to identify key groups of diagnostic transitions. To the best of our knowledge, our dataset is currently the largest astronomical set of molecular lines to which PCA has been applied. The PCA can categorize transitions coming from different physical components in NGC 253 such as i) young starburst tracers characterized by high-excitation transitions of HC3N and complex organic molecules (COMs) versus tracers of on-going star formation (radio recombination lines) and high-excitation transitions of CCH and CN tracing PDRs, ii) tracers of cloud-collision-induced shocks (low-excitation transitions of CH3OH, HNCO, HOCO+, and OCS) versus shocks from star-formation-induced outflows (high-excitation transitions of SiO), as well as iii) outflows showing emission from HOC+, CCH, H3O+, CO isotopologues, HCN, HCO+, CS, and CN. Our findings show these intensities vary with galactic dynamics, star formation activities, and stellar feedback. © 2024, CC BY.

关键词： Principal component analysis

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The application of an extracellular vesicle-based biosensor in early diagnosis and prediction of chemoresponsiveness in ovarian cancer

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Cancer Letters 2024年 581卷 216533-216533页

作者： Tsang, Benjamin K. Asare-Werehene, Meshach Hunter, Rob Gerber, emma Reunov, Arkadiy Brine, Isaiah Chang, Chia-Yu Chang, Chia-Ching Shieh, Dar-Bin Burger, Dylan Anis, Hanan Departments of Obstetrics & Gynecology and Cellular & Molecular Medicine Centre for Infection Immunity and Inflammation Interdisciplinary School of Health Sciences University of Ottawa Ottawa ON K1N 6N5 Canada Chronic Disease Program Ottawa Hospital Research Institute The Ottawa Hospital Ottawa ON K1Y 4E9 Canada Department of Biology St. Francis Xavier University 2320 Notre Dame Avenue Antigonish NS B2G 2W5 Canada School of Electrical Engineering and Computer Science Ottawa-Carleton Institute for Biomedical Engineering University of Ottawa Ottawa ON K1N 6N5 Canada Department of Biological Science and Department of Electrophysics Technology Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B) National Yang Ming Chiao Tung University Hsinchu 30068 Taiwan Institute of Basic Medical Science Institute of Oral Medicine and Department of Stomatology Advanced Optoelectronic Technology Center and Center for Micro/Nano Science and Technology National Cheng Kung University Hospital National Cheng Kung University Tainan 704 Taiwan Institute of Physics Academia Sinica Taipei 10529 Taiwan

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Modeling Atmospheric Lines By the exoplanet Community (MALBeC) version 1.0: A CUISINeS radiative transfer intercomparison project

arXiv

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arXiv 2024年

作者： Villanueva, Geronimo L. Fauchez, Thomas J. Kofman, Vincent Alei, eleonora Lee, elspeth K.H. Janin, estelle Himes, Michael D. Leconte, Jérémy Leung, Michaela Faggi, Sara Mak, Mei Ting Sergeev, Denis e. Kozakis, Thea Manners, James Mayne, Nathan Schwieterman, edward W. Howe, Alex R. Batalha, Natasha NASA Goddard Space Flight Center GreenbeltMD United States Integrated Space Science and Technology Institute Department of Physics American University WashingtonDC United States NASA GSFC Sellers Exoplanet Environments Collaboration United States ETH Zurich Institute for Particle Physics & Astrophysics Wolfgang-Pauli-Str. 27 Zurich8093 Switzerland National Center of Competence in Research Planets Center for Space and Habitability University of Bern Gesellschaftsstrasse 6 BernCH-3012 Switzerland School of Earth and Space Exploration Arizona State University TempeAZ85281 United States Planetary Sciences Group Department of Physics University of Central Florida United States NASA Postdoctoral Program Fellow NASA Goddard Space Flight Center GreenbeltMD United States Laboratoire d’astrophysique de Bordeaux Univ. Bordeaux CNRS B18N allée Geoffroy Saint-Hilaire Pessac33615 France Department of Earth and Planetary Sciences University of California RiversideCA92521 United States Physics and Astronomy University of Exeter ExeterEX4 4QL United Kingdom National Space Institute Technical University of Denmark Elektrovej 328 Kgs. Lyngby2800 Denmark Met Office FitzRoy Road ExeterEX1 3PB United Kingdom Department of Earth and Planetary Sciences University of California RiversideCA United States NASA Goddard Space Flight Center 8800 Greenbelt Rd GreenbeltMD20771 United States Center for Research and Exploration in Space Science and Technology NASA/GSFC GreenbeltMD20771 United States NASA Ames Research Center Mountain ViewCA94035 United States

Radiative transfer (RT) models are critical in the interpretation of exoplanetary spectra, in simulating exoplanet climates and when designing the specifications of future flagship observatories. However, most models differ in methodologies and input data, which can lead to significantly different spectra. In this paper, we present the experimental protocol of the MALBeC (Modeling Atmospheric Lines By the exoplanet Community) project. MALBeC is an exoplanet model intercomparison project (exoMIP) that belongs to the CUISINeS (Climates Using Interactive Suites of Intercomparisons Nested for exoplanet Studies) framework which aims to provide the exoplanet community with a large and diverse set of comparison and validation of models. The proposed protocol tests include a large set of initial participating RT models, a broad range of atmospheres (from Hot Jupiters to temperate terrestrials) and several observation geometries, which would allow us to quantify and compare the differences between different RT models used by the exoplanetary community. Two types of tests are proposed: transit spectroscopy and direct imaging modeling, with results from the proposed tests to be published in dedicated follow-up papers. To encourage the community to join this comparison effort and as an example, we present simulation results for one specific transit case (GJ-1214 b), in which we find notable differences in how the various codes handle the discretization of the atmospheres (e.g., sub-layering), the treatment of molecular opacities (e.g., correlated-k, line-by-line) and the default spectroscopic repositories generally used by each model (e.g., HITRAN, HITeMP, exoMol). © 2024, CC BY.

关键词： Radiative transfer

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An integrated language-vision foundation model for conversational diagnostics and triaging in primary eye care

arXiv

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arXiv 2025年

作者： Soh, Zhi Da Bai, Yang Yu, Kai Zhou, Yang Lei, Xiaofeng Thaku, Sahil Lee, Zann Phang, Lee Ching Linette Peng, Qingsheng Xue, Can Can Chong, Rachel Shujuan Hoang, Quan V. Raghavan, Lavanya Tham, Yih Chung Sabanayagam, Charumathi Wu, Wei-Chi Ho, Ming-Chih He, Jiangnan Gupta, Preeti Lamoureux, ecosse Saw, Seang Mei Nangia, Vinay Panda-Jonas, Songhomitra Xu, Jie Wang, Ya Xing Xu, Xinxing Jonas, Jost B. Wong, Tien Yin Goh, Rick Siow Mong Liu, Yong Cheng, Ching-Yu Singapore Eye Research Institute Singapore National Eye Centre 20 College Road Singapore169856 Singapore Institute of High Performance Computing Agency of Science Technology and Research 1 Fusionopolis Way Singapore138632 Singapore Department of Radiology University of Pennsylvania PhiladephiaPA19104 United States Ophthalmology & Visual Sciences Academic Clinical Program Duke-NUS Medical School 8 College Road 169857 Singapore Department of Ophthalmology Columbia University 622 W 168th New YorkNY United States Street 3rd Floor New YorkNY10032 United States Centre for Innovation and Precision Eye Health National University of Singapore 1E Kent Ridge Road NUHS Tower Block Level 7 Singapore119228 Singapore Department of Ophthalmology Chang Gung Memorial Hospital Linkou Medical Centre Taoyuan No. 123 Dapi Rd. Niaosong District Kaohsiung City83301 Taiwan College of Medicine Chang Gung University Wenhua 1st TaoyuanN0 259 Taiwan road Guishan District Taoyuan333 Taiwan Shanghai Eye Disease Prevention & Treatment Center Shanghai Eye Hospital No. 1440 Hongqiao Road Changning District Shanghai China Duke-NUS Medical School National University of Singapore 8 College Road Singapore169857 Singapore Rothschild Foundation Hospital Institut Français de Myopie Paris 25-29 Rue Manin Paris75019 France Privatpraxis Prof Jonas and Dr. Panda-Jonas Adenauerplatz 2 Heidelberg69115 Germany Beijing Visual Science and Translational Eye Research Institute Beijing Tsinghua Changgung Hospital Tsinghua Medicine Tsinghua University 30 Shuangqing Road Haidian District Beijing100190 China New York eye and Ear Infirmary of Mount Sinai Icahn School of Medicine at Mount Sinai 1 Gustave L. Levy PI New YorkNY10029 United States Suraj Eye Institute Plot No. 559 New Colony Maharashtra Nagpur440001 India Department of Ophthalmology Medical Faculty Heidelberg Heidelberg University Grabengasse 1 Heidelberg69117 Germany Beijing Institute of Ophthalmology Be

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-eyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs) for ocular disease assessment. Meta-eyeFM leverages a routing mechanism to enable accurate task-specific analysis based on text queries. Using Low Rank Adaptation, we fine-tuned our VFMs to detect ocular and systemic diseases, differentiate ocular disease severity, and identify common ocular signs. The model achieved 100% accuracy in routing fundus images to appropriate VFMs, which achieved ≥82.2% accuracy in disease detection, ≥89% in severity differentiation, ≥76% in sign identification. Meta-eyeFM was 11% to 43% more accurate than Gemini-1.5-flash and ChatGPT-4o LMMs in detecting various eye diseases and comparable to an ophthalmologist. This system offers enhanced usability and diagnostic performance, making it a valuable decision support tool for primary eye care or an online LLM for fundus evaluation. © 2025, CC BY-NC-ND.

关键词： Deep learning

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The ALMA Survey of 70 μm Dark High-mass Clumps in early Stages (ASHeS). IX. Physical Properties and Spatial Distribution of Cores in IRDCs

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Astrophysical Journal 2023年第2期950卷 148-148页

作者： Morii, Kaho Sanhueza, Patricio Nakamura, Fumitaka Zhang, Qizhou Sabatini, Giovanni Beuther, Henrik Lu, Xing Li, Shanghuo Garay, Guido Jackson, James M. Olguin, Fernando A. Tafoya, Daniel Tatematsu, Ken’ichi Izumi, Natsuko Sakai, Takeshi Silva, Andrea Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan National Astronomical Observatory of Japan National Institutes of Natural Sciences 2-21-1 Osawa Mitaka Tokyo 181-8588 Japan Astronomical Science Program The Graduate University for Advanced Studies SOKENDAI 2-21-1 Osawa Mitaka Tokyo 181-8588 Japan Center for Astrophysics Harvard & Smithsonian 60 Garden Street Cambridge 02138 MA United States INAF—Istituto di Radioastronomia—Italian node of the ALMA Regional Centre (It-ARC) Via Gobetti 101 Bologna I-40129 Italy INAF Osservatorio Astrofisico di Arcetri Largo E. Fermi 5 Firenze I-50125 Italy Max Planck Institute for Astronomy Konigstuhl 17 Heidelberg D-69117 Germany Shanghai Astronomical Observatory Chinese Academy of Sciences 80 Nandan Road Shanghai 200030 China Departamento de Astronomía Universidad de Chile Las Condes Santiago 7550000 Chile Green Bank Observatory 155 Observatory Rd Green Bank 24944 WV United States Institute of Astronomy Department of physics National Tsing Hua University Hsinchu 30013 Taiwan Department of Space Earth and Environment Chalmers University of Technology Onsala Space Observatory Onsala SE-439 92 Sweden Academia Sinica Institute of Astronomy and Astrophysics 11F of AS/NTU Astronomy-Mathematics Building No.1 Section 4 Roosevelt Road Taipei 10617 Taiwan Graduate School of Informatics and Engineering The University of Electro-Communications Chofu Tokyo 182-8585 Japan

The initial conditions found in infrared dark clouds (IRDCs) provide insights on how high-mass stars and stellar clusters form. We have conducted high-angular resolution and high-sensitivity observations toward thirty-nine massive IRDC clumps, which have been mosaicked using the 12 and 7 m arrays from the Atacama Large Millimeter/submillimeter Array. The targets are 70 μm dark massive (220-4900 M _⊙), dense (>10⁴ cm⁻³), and cold (∼10-20 K) clumps located at distances between 2 and 6 kpc. We identify an unprecedented number of 839 cores, with masses between 0.05 and 81 M _⊙ using 1.3 mm dust continuum emission. About 55% of the cores are low-mass (<1 M _⊙), whereas ≲1% (7/839) are high-mass (≳27 M _⊙). We detect no high-mass prestellar cores. The most massive cores (MMC) identified within individual clumps lack sufficient mass to form high-mass stars without additional mass feeding. We find that the mass of the MMCs is correlated with the clump surface density, implying denser clumps produce more massive cores. There is no significant mass segregation except for a few tentative detections. In contrast, most clumps show segregation once the clump density is considered instead of mass. Although the dust continuum emission resolves clumps in a network of filaments, some of which consist of hub-filament systems, the majority of the MMCs are not found in the hubs. Our analysis shows that high-mass cores and MMCs have no preferred location with respect to low-mass cores at the earliest stages of high-mass star formation. © 2023. The Author(s). Published by the American Astronomical Society.

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The ALMA-QUARKS Survey: II. the ACA 1.3 mm continuum source catalog and the assembly of dense gas in massive star-forming clumps

arXiv

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arXiv 2024年

作者： Xu, Fengwei Wang, Ke Liu, Tie Zhu, Lei Garay, Guido Liu, Xunchuan Goldsmith, Paul Zhang, Qizhou Sanhueza, Patricio Qin, Shengli He, Jinhua Juvela, Mika Tej, Anandmayee Liu, Hongli Li, Shanghuo Morii, Kaho Zhang, Siju Zhou, Jianwen Stutz, Amelia evans, Neal J. Kee-Tae, Kim Liu, Shengyuan Mardones, Diego Li, Guangxing Bronfman, Leonardo Tatematsu, Kenichi Lee, Chang Won Lu, Xing Mai, Xiaofeng Jiao, Sihan Chibueze, James O. Su, Keyun Tóth, L. Viktor Kavli Institute for Astronomy and Astrophysics Peking University Beijing100871 China Department of Astronomy School of Physics Peking University Beijing100871 China Shanghai Astronomical Observatory Chinese Academy of Sciences 80 Nandan Road Shanghai200030 China Chinese Academy of Sciences South America Center for Astronomy National Astronomical Observatories Chinese Academy of Sciences Beijing100101 China Departamento de Astronomía Universidad de Chile Las Condes Santiago7591245 Chile Jet Propulsion Laboratory California Institute of Technology 4800 Oak Grove Drive PasadenaCA91109 United States Center for Astrophysics | Harvard & Smithsonian 60 Garden Street CambridgeMA02138 United States National Astronomical Observatory of Japan National Institutes of Natural Sciences 2-21-1 Osawa Tokyo Mitaka181-8588 Japan Astronomical Science Program The Graduate University for Advanced Studies SOKENDAI 2-21-1 Osawa Tokyo Mitaka181-8588 Japan School of Physics and Astronomy Yunnan University Kunming650091 China Yunnan Observatories Chinese Academy of Sciences 396 Yangfangwang Guandu District Kunming650216 China Department of Physics University of Helsinki PO Box 64 HelsinkiFI-00014 Finland Indian Institute of Space Science and Technology Kerala Thiruvananthapuram695 547 India Max Planck Institute for Astronomy Knigstuhl 17 HeidelbergD-69117 Germany Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan Max-Planck-Institut für Radioastronomie Auf dem Hügel 69 Bonn53121 Germany Departamento de Astronoma Universidad de Concepcion Casilla 160-C Concepción Chile Department of Astronomy The University of Texas AustinTX78712-1205 United States Korea Astronomy and Space Science Institute 776 Daedeokdae-ro Yuseong-gu Daejeon34055 Korea Republic of Institute of Astronomy and Astrophysics Academia Sinica Roosevelt Road Taipei10617 Taiwan South-Western Institute for Astronomy

Leveraging the high resolution, sensitivity, and wide frequency coverage of the Atacama Large Millimeter/submillimeter Array (ALMA), the QUARKS survey, standing for 'Querying Underlying mechanisms of massive star formation with ALMA-Resolved gas Kinematics and Structures', is observing 139 massive star-forming clumps at ALMA Band 6 (λ ∼ 1.3 mm). This paper introduces the Atacama Compact Array (ACA) 7-m data of the QUARKS survey, describing the ACA observations and data reduction. Combining multi-wavelength data, we provide the first edition of QUARKS atlas, offering insights into the multiscale and multiphase interstellar medium (ISM) in high-mass star formation. The ACA 1.3 mm catalog includes 207 continuum sources that are called ACA sources. Their gas kinetic temperatures are estimated using three formaldehyde transitions with a non-LTe radiation transfer model, and the mass and density are derived from a dust emission model. The ACA sources are massive (16-84 percentile values of 6-160 M☉), gravity-dominated (M ∝ R1.1) fragments within massive clumps, with supersonic turbulence (M > 1) and embedded star-forming protoclusters. We find a linear correlation between the masses of the fragments and the massive clumps, with a ratio of 6% between the two. When considering the fragments as representative of dense gas, the ratio indicates a dense gas fraction (DGF) of 6%, although with a wide scatter ranging from 1% to 10%. If we consider the QUARKS massive clumps to be what is observed at various scales, then the size-independent DGF indicates a self-similar fragmentation or collapsing mode in protocluster formation. With the ACA data over four orders of magnitude of luminosity-to-mass ratio (L/M), we find that the DGF increases significantly with L/M, which indicates clump evolutionary stage. We observed a limited fragmentation at the subclump scale, which can be explained by dynamic global collapse process. © 2024, CC BY.

关键词： Kinematics

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A study of Galactic Plane Planck Galactic Cold Clumps observed by SCOPe and the JCMT Plane Survey

arXiv

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arXiv 2024年

作者： eden, D.J. Liu, Tie Moore, T.J.T. Di Francesco, J. Fuller, G. Kim, Kee-Tae Li, Di Liu, S.-Y. Plume, R. Tatematsu, Ken'ichi Thompson, M.A. Wu, Y. Bronfman, L. Butner, H.M. Currie, M.J. Garay, G. Goldsmith, P.F. Hirano, N. Johnstone, D. Juvela, M. Lai, S.-P. Lee, C.W. Mannfors, e.e. Olguin, F. Pattle, K. Park, Geumsook Polychroni, D. Rawlings, M. Rigby, A.J. Sanhueza, P. Traficante, A. Urquhart, J.S. Weferling, B. White, G.J. Yadav, R.K. Armagh Observatory and Planetarium College Hill ArmaghBT61 9DB United Kingdom Shanghai Astronomical Observatory Chinese Academy of Sciences 80 Nandan Road Shanghai200030 China Astrophysics Research Institute Liverpool John Moores University Liverpool Science Park iC2 146 Brownlow Hill. LiverpoolL3 5RF United Kingdom NRC Herzberg Astronomy and Astrophysics 5071 West Saanich Rd VictoriaBCV9E 2E7 Canada Department of Physics and Astronomy University of Victoria VictoriaBCV8W 2Y2 Canada Jodrell Bank Centre for Astrophysics School of Physics and Astronomy The University of Manchester Oxford Road ManchesterM13 9PL United Kingdom Korea Astronomy and Space Science Institute 776 Daedeokdae-ro Yuseong-gu Daejon34055 Korea Republic of 217 Gajeong-ro Yuseong-gu Daejeon34113 Korea Republic of National Astronomical Observatories Chinese Academy of Sciences Beijing100012 China Key Laboratory of Radio Astronomy Chinese Academy of Science Nanjing210008 China Academia Sinica Institute of Astronomy and Astrophysics 11F of AS/NTU Astronomy-Mathematics Building No.1 Sec. 4 Roosevelt Rd Taipei10617 Taiwan Department of Physics and Astronomy University of Calgary 2500 University Drive NW CalgaryABT2N 1N4 Canada Nobeyama Radio Observatory National Astronomical Observatory of Japan National Institutes of Natural Sciences Nobeyama Minamimaki Minamisaku Nagano384-1305 Japan Astronomical Science Program Graduate Institute for Advanced Studies SOKENDAI 2-21-1 Osawa Mitaka Tokyo181-8588 Japan School of Physics and Astronomy University of Leeds LeedsLS2 9JT United Kingdom Department of Astronomy Peking University Beijing100871 China Astronomy Department Universidad de Chile Casilla 36-D Santiago Chile Department of Physics and Astronomy James Madison University MSC 4502 901 Carrier Drive HarrisonburgVA22807 United States RAL Space STFC Rutherford Appleton Laboratory Chilton Didcot OxfordshireOX11 0QX United Kingdom East Asian Observatory

We have investigated the physical properties of Planck Galactic Cold Clumps (PGCCs) located in the Galactic Plane, using the JCMT Plane Survey (JPS) and the SCUBA-2 Continuum Observations of Pre-protostellar evolution (SCOPe) survey. By utilising a suite of molecular-line surveys, velocities and distances were assigned to the compact sources within the PGCCs, placing them in a Galactic context. The properties of these compact sources show no large-scale variations with Galactic environment. Investigating the star-forming content of the sample, we find that the luminosity-to-mass ratio (L/M) is an order of magnitude lower than in other Galactic studies, indicating that these objects are hosting lower levels of star formation. Finally, by comparing ATLASGAL sources that are associated or are not associated with PGCCs, we find that those associated with PGCCs are typically colder, denser, and have a lower L/M ratio, hinting that PGCCs are a distinct population of Galactic Plane sources. Copyright © 2024, The Authors. All rights reserved.

关键词： Stars

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Relative Alignments Between Magnetic Fields, Velocity Gradients, and Dust emission Gradients in NGC 1333

arXiv

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arXiv 2024年

作者： Chen, Michael Chun-Yuan Fissel, Laura M. Sadavoy, Sarah I. Rosolowsky, erik Doi, Yasuo Arzoumanian, Doris Bastien, Pierre Coudé, Simon Di Francesco, James Friesen, Rachel Furuya, Ray S. Hwang, Jihye Inutsuka, Shu-Ichiro Johnstone, Doug Karoly, Janik Kwon, Jungmi Kwon, Woojin Le Gouellec, Valentin J.M. Liu, Hong-Li Mairs, Steve Onaka, Takashi Pattle, Kate Rawlings, Mark G. Tahani, Mehrnoosh Tamura, Motohide Wang, Jia-Wei Department of Physics Engineering Physics and Astronomy Queen’s University KingstonONK7L 3N6 Canada Department of Physics University of Alberta EdmontonABT6G 2E1 Canada Department of Earth Science and Astronomy The University of Tokyo 3-8-1 Komaba Meguro Tokyo153-8902 Japan National Astronomical Observatory of Japan Osawa 2-21-1 Mitaka Tokyo181-8588 Japan Université de Montréal Département de Physique 1375 Avenue Thérèse-Lavoie-Roux MontréalQCH2V 0B3 Canada Department of Earth Environment and Physics Worcester State University WorcesterMA01602 United States Center for Astrophysics | Harvard & Smithsonian 60 Garden Street CambridgeMA02138 United States NRC Herzberg Astronomy and Astrophysics 5071 West Saanich Rd VictoriaBCV9E 2E7 Canada Department of Physics and Astronomy University of Victoria VictoriaBCV8P 5C2 Canada David A. Dunlap Department of Astronomy and Astrophysics University of Toronto 50 St. George Street TorontoONM5S 3H4 Canada Institute of Liberal Arts and Sciences Tokushima University Minami Jousanajima-machi 1-1 Tokushima770-8502 Japan Korea Astronomy and Space Science Institute 776 Daedeokdae-ro Yuseong-gu Daejeon34055 Korea Republic of University of Science and Technology Korea 217 Gajeong-ro Yuseong-gu Daejeon34113 Korea Republic of Department of Physics Graduate School of Science Nagoya University Furo-cho Chikusa-ku Nagoya464-8602 Japan Jeremiah Horrocks Institute University of Central Lancashire PrestonPR1 2HE United Kingdom Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan Department of Earth Science Education Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of NASA Ames Research Center Space Science and Astrobiology Division M.S. 245-6 Moffett FieldCA94035 United States NASA Postdoc

Magnetic fields play an important role in shaping and regulating star formation in molecular clouds. Here, we present one of the first studies examining the relative orientations between magnetic (B) fields and the dust emission, gas column density, and velocity centroid gradients on the 0.02 pc (core) scales, using the BISTRO and VLA+GBT observations of the NGC 1333 star-forming clump. We quantified these relative orientations using the Project Rayleigh Statistic (PRS) and found preferential global parallel alignment between the B field and dust emission gradients, consistent with large-scale studies with Planck. No preferential global alignments, however, are found between the B field and velocity gradients. Local PRS calculated for subregions defined by either dust emission or velocity coherence further revealed that the Bfield does not preferentially align with dust emission gradients in most emission-defined subregions, except in the warmest ones. The velocity-coherent structures, on the other hand, also showed no preferred B field alignments with velocity gradients, except for one potentially bubble-compressed region. Interestingly, the velocity gradient magnitude in NGC 1333 ubiquitously features prominent ripple-like structures that are indicative of magnetohydrodynamic (MHD) waves. Finally, we found B field alignments with the emission gradients to correlate with dust temperature and anticorrelate with column density, velocity dispersion, and velocity gradient magnitude. The latter two anticorrelations suggest that alignments between gas structures and B fields can be perturbed by physical processes that elevate velocity dispersion and velocity gradients, such as infall, accretions, and MHD waves. © 2024, CC BY.

关键词： Plasma magnetohydrodynamic waves

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