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Author Correction: The FLUXNeT2015 dataset and the ONeFlux processing pipeline for eddy covariance data

Scientific data 2021年第1期8卷 72页

作者： Gilberto Pastorello Carlo Trotta eleonora Canfora Housen Chu Danielle Christianson You-Wei Cheah Cristina Poindexter Jiquan Chen Abdelrahman elbashandy Marty Humphrey Peter Isaac Diego Polidori Markus Reichstein Alessio Ribeca Catharine van Ingen Nicolas Vuichard Leiming Zhang Brian Amiro Christof Ammann M Altaf Arain Jonas Ardö Timothy Arkebauer Stefan K Arndt Nicola Arriga Marc Aubinet Mika Aurela Dennis Baldocchi Alan Barr eric Beamesderfer Luca Belelli Marchesini Onil Bergeron Jason Beringer Christian Bernhofer Daniel Berveiller Dave Billesbach Thomas Andrew Black Peter D Blanken Gil Bohrer Julia Boike Paul V Bolstad Damien Bonal Jean-Marc Bonnefond David R Bowling Rosvel Bracho Jason Brodeur Christian Brümmer Nina Buchmann Benoit Burban Sean P Burns Pauline Buysse Peter Cale Mauro Cavagna Pierre Cellier Shiping Chen Isaac Chini Torben R Christensen James Cleverly Alessio Collalti Claudia Consalvo Bruce D Cook David Cook Carole Coursolle edoardo Cremonese Peter S Curtis ettore D'Andrea Humberto da Rocha Xiaoqin Dai Kenneth J Davis Bruno De Cinti Agnes de Grandcourt Anne De Ligne Raimundo C De Oliveira Nicolas Delpierre Ankur R Desai Carlos Marcelo Di Bella Paul di Tommasi Han Dolman Francisco Domingo Gang Dong Sabina Dore Pierpaolo Duce eric Dufrêne Allison Dunn Jiří Dušek Derek eamus Uwe eichelmann Hatim Abdalla M elKhidir Werner eugster Cacilia M ewenz Brent ewers Daniela Famulari Silvano Fares Iris Feigenwinter Andrew Feitz Rasmus Fensholt Gianluca Filippa Marc Fischer John Frank Marta Galvagno Mana Gharun Damiano Gianelle Bert Gielen Beniamino Gioli Anatoly Gitelson Ignacio Goded Mathias Goeckede Allen H Goldstein Christopher M Gough Michael L Goulden Alexander Graf Anne Griebel Carsten Gruening Thomas Grünwald Albin Hammerle Shijie Han Xingguo Han Birger Ulf Hansen Chad Hanson Juha Hatakka Yongtao He Markus Hehn Bernard Heinesch Nina Hinko-Najera Lukas Hörtnagl Lindsay Hutley Andreas Ibrom Hiroki Ikawa Marcin Jackowicz-Korczynski Dalibor Janouš Wilma Jans Rachhpal Jassal Shicheng Jiang Tomomichi Kato Myr Computational Research Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA. gzpastorello@lbl.gov. DIBAF University of Tuscia Viterbo 01100 Italy. Euro-Mediterranean Centre on Climate Change Foundation (CMCC) Lecce 73100 Italy. Climate & Ecosystem Sciences Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA. Computational Research Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA. Department of Civil Engineering California State University Sacramento CA 95819 USA. Department of Geography Environment and Spatial Sciences Michigan State University East Lansing MI 48823 USA. Department of Computer Science University of Virginia Charlottesville VA 22904 USA. TERN Ecosystem Processes Menzies Creek VIC3159 Australia. Max Planck Institute for Biogeochemistry Jena 07701 Germany. Laboratoire des Sciences du Climat et de l'Environnement (LSCE) CEA CNRS UVSQ UPSACLAY Gif sur Yvette 91190 France. Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China. Department of Soil Science University of Manitoba Winnipeg MB R3T2N2 Canada. Department of Agroecology and Environment Agroscope Research Institute Zürich 8046 Switzerland. School of Geography and Earth Sciences McMaster University L8S4K1 Hamilton ON Canada. Department of Physical Geography and Ecosystem Science Lund University Lund 22362 Sweden. Department of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE 68583 USA. School of Ecosystem and Forest Sciences The University of Melbourne Richmond VIC3121 Australia. Department of Biology Research Group PLECO University of Antwerp Antwerp 2610 Belgium. Joint Research Centre European Commission Ispra 21027 Italy. TERRA Teaching and Research Center University of Liege Gembloux B-5030 Belgium. Finnish Meteorological Institute Helsinki 00560 Finland. ES

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Proceedings from the IV Brazilian Meeting on Research Integrity, science and Publication ethics (IV BRISPe)

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Research Integrity and Peer Review 2017年第1期2卷 1-12页

作者： Sonia Vasconcelos edson Watanabe L. P. Garcia e. Duarte M. C. Cassimiro M. M. P. Diós-Borges A. M. M. Soares C. H. Debenedito Silva A. A. P. Santa Rosa G. A. Fófano H. S. Pinheiro A. M. Gollner C. C. Santos S. M. R. Vasconcelos D. C. Machado P. V. S. Souza R. T. Souza M. D Ribeiro P. Biancovilli M. Fontes-Domingues V. C. Garbocci R. Neves M. D. Ribeiro R. Amaral M. M. M. Machado P. M. Lourenço V. Ronchi A. C. Furnival L. S. Gracioso M. D. P. Silva F. M. Litto M. Patrão Neves A. S. Carvalho J. Araújo S. Liskauskas R. Kant de Lima S. C. Bourguignon F. R. Mota H. G. Falcão J. C. Amaral A. C. Quintela A. Schtscherbyna A. Palma C. A. Guimarães D. Foguel e. H. Watanabe R. M. V. R. Almeida J. R. Lapa e Silva M. M. Sorenson B. C. Machado A. P. Vicentini A. A. B. Almodóvar R. M. Catarino H. H. Caiaffa Filho e. Damasio J. Leta L. V. R. Rezende S. Cruz-Riascos A. Abreu M. Russo P. G. Camacho M. Palácios N. R. A. Silva M. R. C. G. Novaes D. Guilhem H. S Selistre-de-Araujo A. S. C. Abreu Science Education Program Institute of Medical Biochemistry Leopoldo de Meis (IBqM) Federal University of Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Committee on Research Integrity (CRI) Advisory Council for Research Ethics (CTEP) Federal University of Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Electrical Engineering Program (PEE) Institute Alberto Luiz Coimbra of Graduate Studies and Research in Engineering (COPPE) Federal University of Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Institute for Applied Economic Research (IPEA) Brasília Federal District Brazil Secretary for Health Surveillance Ministry of Health Brasília Federal District Brazil Scientific Integrity Committee Oswaldo Cruz Foundation Oswaldo Cruz Institute (IOC/FIOCRUZ) Rio de Janeiro Brazil Scientific Integrity Committee Oswaldo Cruz Institute Oswaldo Cruz Foundation (IOC/FIOCRUZ) Rio de Janeiro Brazil Bioethics Institute Catholic University of Portugal Porto Portugal Rio de Janeiro State University (UERJ) Rio de Janeiro Brazil National Cancer Institute (INCA) Cancer Hospital IV - Ethics Committee for Clinical Research Rio de Janeiro Brazil Federal General Hospital of Bonsucesso Rio de Janeiro Brazil Human Research Ethics Committee University Hospital of Juiz de Fora (HU-UJFJ) Juiz de Fora Minas Gerais Brazil Faculty of Southeastern Minas Gerais (FACSUM) Juiz de Fora Minas Gerais Brazil São Pedro Educational Institute (IESPe) Juiz de Fora Minas Gerais Brazil University Hospital of Juiz de Fora (HU-UJFJ) Juiz de Fora Minas Gerais Brazil Department of Biology and Sciences Pedro II School Rio de Janeiro Brazil Science Education Program Institute of Medical Biochemistry Leopoldo de Meis Federal University of Rio de Janeiro (IBqM/UFRJ) Rio de Janeiro Brazil Professional Masters Program in Science Education Institute of Medical Biochemistry Leopoldo de Meis (IBqM) Federal University of Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Research Ethics Committee Clementino Fraga Filho University Hos

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (vol 50, pg 1412, 2018)

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NATURe GeNeTICS 2018年第12期50卷 1755-1755页

作者： evangelou, evangelos Warren, Helen R. Mosen-Ansorena, David Mifsud, Borbala Pazoki, Raha Gao, He Ntritsos, Georgios Dimou, Niki Cabrera, Claudia P. Karaman, Ibrahim Fu Liang Ng evangelou, Marina Witkowska, Katarzyna Tzanis, evan Hellwege, Jacklyn N. Giri, Ayush edwards, Digna R. Velez Sun, Yan V. Cho, Kelly Gaziano, J. Michael Wilson, Peter W. F. Tsao, Philip S. Kovesdy, Csaba P. esko, Tonu Magi, Reedik Milani, Lili Almgren, Peter Boutin, Thibaud Debette, Stephanie Ding, Jun Giulianini, Franco Holliday, elizabeth G. Jackson, Anne U. Li-Gao, Ruifang Lin, Wei-Yu Luan, Jian'an Mangino, Massimo Oldmeadow, Christopher Prins, Bram Peter Qian, Yong Sargurupremraj, Muralidharan Shah, Nabi Surendran, Praveen Theriault, Sebastien Verweij, Niek Willems, Sara M. Zhao, Jing-Hua Amouyel, Philippe Connell, John de Mutsert, Renee Doney, Alex S. F. Farrall, Martin Menni, Cristina Morris, Andrew D. Noordam, Raymond Pare, Guillaume Poulter, Neil R. Shields, Denis C. Stanton, Alice Thom, Simon Abecasis, Goncalo Amin, Najaf Arking, Dan e. Ayers, Kristin L. Barbieri, Caterina M. Batini, Chiara Bis, Joshua C. Blake, Tineka Bochud, Murielle Boehnke, Michael Boerwinkle, eric Boomsma, Dorret I. Bottinger, erwin P. Braund, Peter S. Brumat, Marco Campbell, Archie Campbell, Harry Chakravarti, Aravinda Chambers, John C. Chauhan, Ganesh Ciullo, Marina Cocca, Massimiliano Collins, Francis Cordell, Heather J. Davies, Gail de Borst, Martin H. de Geus, eco J. Deary, Ian J. Deelen, Joris Del Greco, Fabiola M. Demirkale, Cumhur Yusuf Dorr, Marcus ehret, Georg B. elosua, Roberto enroth, Stefan erzurumluoglu, A. Mesut Ferreira, Teresa Franberg, Mattias Franco, Oscar H. Gandin, Ilaria Gasparini, Paolo Giedraitis, Vilmantas Gieger, Christian Girotto, Giorgia Goel, Anuj Gow, Alan J. Gudnason, Vilmundur Guo, Xiuqing Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Harris, Sarah e. Hartman, Catharina A. Havulinna, Aki S. Hicks, Andrew A. Hofer, edith Hofman, Albert Hottenga, Jouke-Jan Huffman, Jennifer e. Hwang, Shih-Jen Ingelsson, erik James, Alan Jansen Department of Epidemiology and Biostatistics Imperial College London London UK Department of Hygiene and Epidemiology University of Ioannina Medical School Ioannina Greece William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK National Institute for Health Research Barts Cardiovascular Biomedical Research Center Queen Mary University of London London UK MRC-PHE Centre for Environment and Health Imperial College London London UK Department of Mathematics Imperial College London London UK Division of Epidemiology Department of Medicine Institute for Medicine and Public Health Vanderbilt Genetics Institute Vanderbilt University Medical Center Tennessee Valley Healthcare System (626)/Vanderbilt University Nashville TN USA Vanderbilt Genetics Institute Vanderbilt Epidemiology Center Department of Obstetrics and Gynecology Vanderbilt University Medical Center Tennessee Valley Health Systems VA Nashville TN USA Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA Department of Biomedical Informatics Emory University School of Medicine Atlanta GA USA Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC) VA Boston Healthcare System Boston MA USA Division of Aging Department of Medicine Brigham and Women’s Hospital Department of Medicine Harvard Medical School Boston MA USA Atlanta VAMC and Emory Clinical Cardiovascular Research Institute Atlanta GA USA VA Palo Alto Health Care System Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA Nephrology Section Memphis VA Medical Center and University of Tennessee Health Science Center Memphis TN USA Estonian Genome Center University of Tartu Tartu Estonia Program in Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA Department Clinical Sciences Malmö Lund University Malmö Sweden MRC Human Genetics Un

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of european ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.

关键词： Cardiovascular diseases Genome informatics Genome-wide association studies

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Author Correction: Global status and conservation potential of reef sharks

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Nature 2020年第7825期585卷 E11页

作者： M Aaron MacNeil Demian D Chapman Michelle Heupel Colin A Simpfendorfer Michael Heithaus Mark Meekan euan Harvey Jordan Goetze Jeremy Kiszka Mark e Bond Leanne M Currey-Randall Conrad W Speed C Samantha Sherman Matthew J Rees Vinay Udyawer Kathryn I Flowers Gina Clementi Jasmine Valentin-Albanese Taylor Gorham M Shiham Adam Khadeeja Ali Fabián Pina-Amargós Jorge A Angulo-Valdés Jacob Asher Laura García Barcia Océane Beaufort Cecilie Benjamin Anthony T F Bernard Michael L Berumen Stacy Bierwagen erika Bonnema Rosalind M K Bown Darcy Bradley edd Brooks J Jed Brown Dayne Buddo Patrick Burke Camila Cáceres Diego Cardeñosa Jeffrey C Carrier Jennifer e Caselle Venkatesh Charloo Thomas Claverie eric Clua Jesse e M Cochran Neil Cook Jessica Cramp Brooke D'Alberto Martin de Graaf Mareike Dornhege Andy estep Lanya Fanovich Naomi F Farabaugh Daniel Fernando Anna L Flam Camilla Floros Virginia Fourqurean Ricardo Garla Kirk Gastrich Lachlan George Rory Graham Tristan Guttridge Royale S Hardenstine Stephen Heck Aaron C Henderson Heidi Hertler Robert Hueter Mohini Johnson Stacy Jupiter Devanshi Kasana Steven T Kessel Benedict Kiilu Taratu Kirata Baraka Kuguru Fabian Kyne Tim Langlois elodie J I Lédée Steve Lindfield Andrea Luna-Acosta Jade Maggs B Mabel Manjaji-Matsumoto Andrea Marshall Philip Matich erin McCombs Dianne McLean Llewelyn Meggs Stephen Moore Sushmita Mukherji Ryan Murray Muslimin Kaimuddin Stephen J Newman Josep Nogués Clay Obota Owen O'Shea Kennedy Osuka Yannis P Papastamatiou Nishan Perera Bradley Peterson Alessandro Ponzo Andhika Prasetyo L M Sjamsul Quamar Jessica Quinlan Alexei Ruiz-Abierno enric Sala Melita Samoilys Michelle Schärer-Umpierre Audrey Schlaff Nikola Simpson Adam N H Smith Lauren Sparks Akshay Tanna Rubén Torres Michael J Travers Maurits van Zinnicq Bergmann Laurent Vigliola Juney Ward Alexandra M Watts Colin Wen elizabeth Whitman Aaron J Wirsing Aljoscha Wothke esteban Zarza-Gonzâlez Joshua e Cinner Department of Biology Dalhousie University Halifax Nova Scotia Canada. a.macneil@dal.ca. Institute of Environment Department of Biological Sciences Florida International University North Miami FL USA. Australian Institute of Marine Science Townsville Queensland Australia. Centre for Sustainable Tropical Fisheries and Aquaculture James Cook University Townsville Queensland Australia. Australian Institute of Marine Science Crawley Western Australia Australia. The UWA Oceans Institute The University of Western Australia Crawley Western Australia Australia. School of Molecular and Life Sciences Curtin University Bentley Western Australia Australia. Marine Program Wildlife Conservation Society New York NY USA. Centre for Sustainable Ecosystems Solutions School of Earth Atmospheric and Life Sciences University of Wollongong Wollongong New South Wales Australia. Australian Institute of Marine Science Arafura Timor Research Facility Darwin Northern Territory Australia. School of Marine and Atmospheric Science Stony Brook University Stony Brook NY USA. Department of Biology Dalhousie University Halifax Nova Scotia Canada. International Pole and Line Foundation Malé Maldives. Maldives Marine Research Institute Ministry of Fisheries Marine Resources and Agriculture Malé Maldives. Centro de Investigaciones de Ecosistemas Costeros (CIEC) Cayo Coco Morón Ciego de Ávila Cuba. Centro de Investigaciones Marinas Universidad de la Habana Havana Cuba. Galbraith Marine Science Laboratory Eckerd College St Petersburg FL USA. Joint Institute for Marine and Atmospheric Research University of Hawaii at Manoa Honolulu HI USA. Habitat and Living Marine Resources Program Ecosystem Sciences Division Pacific Islands Fisheries Science Center National Oceanic and Atmospheric Administration Honolulu HI USA. Réseau requins des Antilles Francaises Kap Natirel Vieux-Fort Guadeloupe. Mahonia Na Dari Research and Conservation Centre Kimbe Papua New Guinea. South African

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Subnational mapping of HIV incidence and mortality among individuals aged 15–49 years in sub-Saharan Africa, 2000–18: a modelling study

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The Lancet HIV 2021年第6期8卷 e363-e375页

作者： Sartorius, Benn VanderHeide, John D. Yang, Mingyou Goosmann, erik A. Hon, Julia Haeuser, emily Cork, Michael A. Perkins, Samantha Jahagirdar, Deepa Schaeffer, Lauren e. Serfes, Audrey L. LeGrand, Kate e. Abbastabar, Hedayat Abebo, Zeleke Hailemariam Abosetugn, Akine eshete Abu-Gharbieh, eman Accrombessi, Manfred Mario Kokou Adebayo, Oladimeji M. Adegbosin, Adeyinka emmanuel Adekanmbi, Victor Adetokunboh, Olatunji O. Adeyinka, Daniel Adedayo Ahinkorah, Bright Opoku Ahmadi, Keivan Ahmed, Muktar Beshir Akalu, Yonas Akinyemi, Oluwaseun Oladapo Akinyemi, Rufus Olusola Aklilu, Addis Akunna, Chisom Joyqueenet Alahdab, Fares Al-Aly, Ziyad Alam, Noore Alamneh, Alehegn Aderaw Alanzi, Turki M. Alemu, Biresaw Wassihun Alhassan, Robert Kaba Ali, Tilahun Alipour, Vahid Amini, Saeed Ancuceanu, Robert Ansari, Fereshteh Anteneh, Zelalem Alamrew Anvari, Davood Anwer, Razique Appiah, Seth Christopher Yaw Arabloo, Jalal Asemahagn, Mulusew A. Asghari Jafarabadi, Mohammad Asmare, Wondwossen Niguse Atnafu, Desta Debalkie Atout, Maha Moh'd Wahbi Atreya, Alok Ausloos, Marcel Awedew, Atalel Fentahun Ayala Quintanilla, Beatriz Paulina Ayanore, Martin Amogre Aynalem, Yared Asmare Ayza, Muluken Altaye Azari, Samad Azene, Zelalem Nigussie Babar, Zaheer-Ud-Din Baig, Atif Amin Balakrishnan, Senthilkumar Banach, Maciej Bärnighausen, Till Winfried Basu, Sanjay Bayati, Mohsen Bedi, Neeraj Bekuma, Tariku Tesfaye Bezabhe, Woldesellassie M. Mequanint Bhagavathula, Akshaya Srikanth Bhardwaj, Pankaj Bhattacharyya, Krittika Bhutta, Zulfiqar A. Bibi, Sadia Bikbov, Boris Birhan, Tsegaye Adane Bitew, Zebenay Workneh Bockarie, Moses John Boloor, Archith Brady, Oliver J. Bragazzi, Nicola Luigi Briko, Andrey Nikolaevich Briko, Nikolay Ivanovich Burugina Nagaraja, Sharath Butt, Zahid A. Cárdenas, Rosario Carvalho, Felix Charan, Jaykaran Chatterjee, Souranshu Chattu, Soosanna Kumary Chattu, Vijay Kumar Chowdhury, Mohiuddin Ahsanul Kabir Chu, Dinh-Toi Cook, Aubrey J. Cormier, Natalie Maria Cowden, Richard G. Culquichicon, Carlos Dagnew, Baye Dahlawi, Saad M.A. D Centre for Tropical Medicine and Global Health Nuffield Department of Medicine University of Oxford Oxford United Kingdom Malaria Atlas Project University of Oxford Oxford United Kingdom The George Institute for Global Health University of Oxford Oxford United Kingdom Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Global Health University of Washington Seattle WA United States Department of Medicine University of Washington Seattle WA United States Insights Program Bill and Melinda Gates Foundation Seattle WA United States Global Programs Medical Teams International Seattle WA United States Department of Pediatric Newborn Medicine Brigham and Women's Hospital Boston MA United States Advanced Diagnostic and Interventional Radiology Research Center Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Center Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Pediatric Chronic Kidney Disease Research Center Tehran University of Medical Sciences Tehran Iran Department of Environmental Health Engineering Tehran University of Medical Sciences Tehran Iran Metabolomics and Genomics Research Center Tehran University of Medical Sciences Tehran Iran Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Department of Public Health Arba Minch University Arba Minch Ethiopia Department of Medical Laboratory Sciences Arba Minch University Arba Minch Ethiopia College of Medicine and Health Science Arba Minch University Arba Minch Ethiopia Department of Nursing Arba Minch University Arba Minch Ethiopia Department of Biomedical Sciences Arba Minch University Arba Minch Ethiopia Department of Public Health Debre Berhan University Debre Brehan

Background: High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods: In this modelling study, we developed a framework that used the geographically specific HIV prevalence data collected in seroprevalence surveys and antenatal care clinics to train a model that estimates HIV incidence and mortality among individuals aged 15–49 years. We used a model-based geostatistical framework to estimate HIV prevalence at the second administrative level in 44 countries in sub-Saharan Africa for 2000–18 and sought data on the number of individuals on antiretroviral therapy (ART) by second-level administrative unit. We then modified the estimation and Projection Package (ePP) to use these HIV prevalence and treatment estimates to estimate HIV incidence and mortality by second-level administrative unit. Findings: The estimates suggest substantial variation in HIV incidence and mortality rates both between and within countries in sub-Saharan Africa, with 15 countries having a ten-times or greater difference in estimated HIV incidence between the second-level administrative units with the lowest and highest estimated incidence levels. Across all 44 countries in 2018, HIV incidence ranged from 2·8 (95% uncertainty interval 2·1–3·8) in Mauritania to 1585·9 (1369·4–1824·8) cases per 100 000 people in Lesotho and HIV mortality ranged from 0·8 (0·7–0·9) in Mauritania to 676·5 (513·6–888·0) deaths per 100 000 people in Lesotho. Variation in both incidence and mortality was substantially greater at the subnational level than at the national level and the highest estimated rates were accordingly higher. Among second-level administrative units, Guijá District, Gaza Province, Mozambique,

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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 765, 2017)

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NATURe GeNeTICS 2018年第5期50卷 765-766页

作者： Turcot, Valerie Lu, Yingchang Highland, Heather M. Schurmann, Claudia Justice, Anne e. Fine, Rebecca S. Bradfield, Jonathan P. esko, Tonu Giri, Ayush Graff, Mariaelisa Guo, Xiuqing Hendricks, Audrey e. Karaderi, Tugce Lempradl, Adelheid Locke, Adam e. Mahajan, Anubha Marouli, eirini Sivapalaratnam, Suthesh Young, Kristin L. Alfred, Tamuno Feitosa, Mary F. Masca, Nicholas G. D. Manning, Alisa K. Medina-Gomez, Carolina Mudgal, Poorva Ng, Maggie C. Y. Reiner, Alex P. Vedantam, Sailaja Willems, Sara M. Winkler, Thomas W. Abecasis, Goncalo Aben, Katja K. Alam, Dewan S. Alharthi, Sameer e. Allison, Matthew Amouyel, Philippe Asselbergs, Folkert W. Auer, Paul L. Balkau, Beverley Bang, Lia e. Barroso, Ines Bastarache, Lisa Benn, Marianne Bergmann, Sven Bielak, Lawrence F. Bluher, Matthias Boehnke, Michael Boeing, Heiner Boerwinkle, eric Boger, Carsten A. Bork-Jensen, Jette Bots, Michiel L. Bottinger, erwin P. Bowden, Donald W. Brandslund, Ivan Breen, Gerome Brilliant, Murray H. Broer, Linda Brumat, Marco Burt, Amber A. Butterworth, Adam S. Campbell, Peter T. Cappellani, Stefania Carey, David J. Catamo, eulalia Caulfield, Mark J. Chambers, John C. Chasman, Daniel I. Chen, Yii-Der I. Chowdhury, Rajiv Christensen, Cramer Chu, Audrey Y. Cocca, Massimiliano Collins, Francis S. Cook, James P. Corley, Janie Galbany, Jordi Corominas Cox, Amanda J. Crosslin, David S. Cuellar-Partida, Gabriel D'eustacchio, Angela Danesh, John Davies, Gail Bakker, Paul I. W. Groot, Mark C. H. Mutsert, Renee Deary, Ian J. Dedoussis, George Demerath, ellen W. Heijer, Martin Hollander, Anneke I. Ruijter, Hester M. Dennis, Joe G. Denny, Josh C. Angelantonio, emanuele Drenos, Fotios Du, Mengmeng Dube, Marie-Pierre Dunning, Alison M. easton, Douglas F. edwards, Todd L. ellinghaus, David ellinor, Patrick T. elliott, Paul evangelou, evangelos Farmaki, Aliki-eleni Farooqi, I. Sadaf Faul, Jessica D. Fauser, Sascha Feng, Shuang Ferrannini, ele Ferrieres, Jean Florez, Jose C. Ford, Ian Fornage, Myriam Franco, Oscar H. Franke, Andre Franks, Paul W. Friedrich, Ne Montreal Heart Institute Université de Montréal Montreal Quebec Canada Division of Epidemiology Department of Medicine Vanderbilt-Ingram Cancer Center Vanderbilt Epidemiology Center Vanderbilt University School of Medicine Nashville TN USA Charles Bronfman Institute for Personalized Medicine Icahn School of Medicine at Mount Sinai New York NY USA Genetics of Obesity and Related Metabolic Traits Program Icahn School of Medicine at Mount Sinai New York NY USA Department of Epidemiology University of North Carolina Chapel Hill NC USA Human Genetics Center University of Texas School of Public Health University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences University of Texas Health Science Center at Houston Houston TX USA Broad Institute of MIT and Harvard Cambridge MA USA Department of Genetics Harvard Medical School Boston MA USA Division of Endocrinology and Center for Basic and Translational Obesity Research Boston Children’s Hospital Boston MA USA Center for Applied Genomics Division of Human Genetics Children’s Hospital of Philadelphia Philadelphia PA USA Quantinuum Research LLC San Diego CA USA Estonian Genome Center University of Tartu Tartu Estonia Division of Epidemiology Department of Medicine Institute for Medicine and Public Health Vanderbilt Genetics Institute Vanderbilt University Nashville TN USA Institute for Translational Genomics and Population Sciences LABioMed at Harbor-UCLA Medical Center Torrance CA USA Wellcome Trust Sanger Institute Hinxton UK Department of Mathematical and Statistical Sciences University of Colorado Denver CO USA Wellcome Trust Centre for Human Genetics University of Oxford Oxford UK Department of Biological Sciences Faculty of Arts and Sciences Eastern Mediterranean University Famagusta Cyprus Max Planck Institute of Immunobiology and Epigenetics Freiburg Germany Department of Biostatistics and Center for Statistical Genetics University of Michigan Ann Arbor

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains challenging. Here we combined data from 718,734 individuals to discover rare and low-frequency (minor allele frequency (MAF) < 5%) coding variants associated with BMI. We identified 14 coding variants in 13 genes, of which 8 variants were in genes (ZBTB7B, ACHe, RAPGeF3, RAB21, ZFHX3, eNTPD6, ZFR2 and ZNF169) newly implicated in human obesity, 2 variants were in genes (MC4R and KSR2) previously observed to be mutated in extreme obesity and 2 variants were in GIPR. The effect sizes of rare variants are ~10 times larger than those of common variants, with the largest effect observed in carriers of an MC4R mutation introducing a stop codon (***35Ter, MAF = 0.01%), who weighed ~7 kg more than non-carriers. Pathway analyses based on the variants associated with BMI confirm enrichment of neuronal genes and provide new evidence for adipocyte and energy expenditure biology, widening the potential of genetically supported therapeutic targets in obesity.

关键词： Genome-wide association studies Obesity

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Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Nature genetics 2019年第7期51卷 1191-1192页

作者： Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne e Justice Rebecca S Fine Jonathan P Bradfield Tõnu esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey e Hendricks Tugce Karaderi Adelheid Lempradl Adam e Locke Anubha Mahajan eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer e Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia e Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F easton Todd L edwards David ellinghaus Patrick T ellinor Paul elliott evangelos evangelou Aliki-eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel e Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Montreal Heart Institute Université de Montréal Montreal Quebec Canada. Division of Epidemiology Department of Medicine Vanderbilt-Ingram Cancer Center Vanderbilt Epidemiology Center Vanderbilt University School of Medicine Nashville TN USA. Charles Bronfman Institute for Personalized Medicine Icahn School of Medicine at Mount Sinai New York NY USA. Genetics of Obesity and Related Metabolic Traits Program Icahn School of Medicine at Mount Sinai New York NY USA. Department of Epidemiology University of North Carolina Chapel Hill NC USA. Human Genetics Center University of Texas School of Public Health University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences University of Texas Health Science Center at Houston Houston TX USA. Broad Institute of MIT and Harvard Cambridge MA USA. Department of Genetics Harvard Medical School Boston MA USA. Division of Endocrinology and Center for Basic and Translational Obesity Research Boston Children's Hospital Boston MA USA. Center for Applied Genomics Division of Human Genetics Children's Hospital of Philadelphia Philadelphia PA USA. Quantinuum Research LLC San Diego CA USA. Estonian Genome Center University of Tartu Tartu Estonia. Division of Epidemiology Department of Medicine Institute for Medicine and Public Health Vanderbilt Genetics Institute Vanderbilt University Nashville TN USA. Institute for Translational Genomics and Population Sciences LABioMed at Harbor-UCLA Medical Center Torrance CA USA. Wellcome Trust Sanger Institute Hinxton UK. Department of Mathematical and Statistical Sciences University of Colorado Denver CO USA. Wellcome Trust Centre for Human Genetics University of Oxford Oxford UK. Department of Biological Sciences Faculty of Arts and Sciences Eastern Mediterranean University Famagusta Cyprus. Max Planck Institute of Immunobiology and Epigenetics Freiburg Germany. Department of Biostatistics and Center for Statistical Genetics University of M

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Notes for genera:Ascomycota

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Fungal Diversity 2017年第5期86卷 1-594页

作者： Nalin N.Wijayawardene Kevin D.Hyde Kunhiraman C.Rajeshkumar David L.Hawksworth Hugo Madrid Paul M.Kirk Uwe Braun Rajshree V.Singh Pedro W.Crous Martin Kukwa Robert Lücking Cletus P.Kurtzman Andrey Yurkov Danny Haelewaters Andre´Aptroot H.Thorsten Lumbsch einar Timdal Damien ertz Javier etayo Alan J.L.Phillips Johannes Z.Groenewald Moslem Papizadeh Laura Selbmann Monika C.Dayarathne Gothamie Weerakoon e.B.Gareth Jones Satinee Suetrong Qing Tian Rafael F.Castanda-Ruiz Ali H.Bahkali Ka-Lai Pang Kazuaki Tanaka Dong Qin Dai Jariya Sakayaroj Martina Hujslová Lorenzo Lombard Belle D.Shenoy Ave Suija Sajeewa S.N.Maharachchikumbura Kasun M.Thambugala Dhanushka N.Wanasinghe Bharati O.Sharma Subhash Gaikwad Gargee Pandit Laura Zucconi Silvano Onofri eleonora egidi Huzefa A.Raja Rampai Kodsueb Marcela e.S.Caceres Sergio Perez-Ortega Patrícia O.Fiuza Josiane Santana Monteiro Larissa N.Vasilyeva Roger G.Shivas Maria Prieto Mats Wedin Ibai Olariaga Adebola Azeez Lateef Yamini Agrawal Seyed Abolhassan Shahzadeh Fazeli Mohammad Ali Amoozegar Guo Zhu Zhao Walter P.Pfliegler Gunjan Sharma Magdalena Oset Mohamed A.Abdel-Wahab Susumu Takamatsu Konstanze Bensch Nimali Indeewari de Silva AndréDe Kesel Anuruddha Karunarathna Saranyaphat Boonmee Donald H.Pfister Yong-Zhong Lu Zong-Long Luo Nattawut Boonyuen Dinushani A.Daranagama Indunil C.Senanayake Subashini C.Jayasiri Milan C.Samarakoon Xiang-Yu Zeng Mingkwan Doilom Luis Quijada Sillma Rampadarath Gabriela Heredia Asha J.Dissanayake Ruvishika S.Jayawardana Rekhani H.Perera Li Zhou Tang Chayanard Phukhamsakda Margarita Hernańdez-Restrepo Xiaoya Ma Saowaluck Tibpromma Luis F.P.Gusmao Darshani Weerahewa Samantha C.Karunarathna Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand National Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology(Fungi)GroupAgharkar Research InstitutePuneMaharashtra 411004India Royal Botanic Gardens KewRichmondSurrey TW93DSUK Department of Life Sciences The Natural History MuseumCromwell RoadLondon SW75BDUK Jilin Agricultural University Changchun 130118JilinPeople’s Republic of China Centro de Geno´mica y Bioinforma´tica Facultad de CienciasUniversidad Mayor de ChileCamino La Pira´mide 5750HuechurabaSantiagoChile Martin-Luther-Universita¨t Institut fu¨r BiologieBereich Geobotanik und Botanischer GartenHerbariumNeuwerk 2106099 Halle(Saale)Germany Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands Department of Plant Taxonomy and Nature Conservation Faculty of BiologyUniversity of Gdan´skWita Stwosza 5980-308 Gdan´skPoland Botanic Garden and Botanical Museum Königin-Luise-Str.6-814195 BerlinGermany Mycotoxin Prevention and Applied Microbiology Research Unit National Center for Agricultural Utilization ResearchAgricultural Research ServiceU.S.Department of AgriculturePeoriaIL 61604USA Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures Inhoffenstraße 7B38124 BrunswickGermany Farlow Reference Library and Herbarium of Cryptogamic Botany Harvard University22 Divinity AvenueCambridgeMA 02138USA Department of Organismic and Evolutionary Biology Harvard University22 Divinity AvenueCambridgeMA 02138USA ABL Herbarium G.v.d.Veenstraat 1073762 XK SoestThe Netherlands Science&Education The Field Museum1400

Knowledge of the relationships and thus the classification of fungi,has developed rapidly with increasingly widespread use of molecular techniques,over the past 10–15 years,and continues to *** genera have been found to be polyphyletic,and their generic concepts have subsequently been *** names have thus been introduced for species which are phylogenetically distinct from the type species of particular *** ending of the separate naming of morphs of the same species in 2011,has also caused changes in fungal generic *** order to facilitate access to all important changes,it was desirable to compile these in a single *** present article provides a list of generic names of Ascomycota(approximately 6500 accepted names published to the end of 2016),including those which are *** and summaries of the changes since the last edition of‘Ainsworth&Bisby’s Dictionary of the Fungi’in 2008 are *** notes include the number of accepted species,classification,type species(with location of the type material),culture availability,life-styles,distribution,and selected publications that have appeared since *** work is intended to provide the foundation for updating the ascomycete component of the"Without prejudice list of generic names of Fungi"published in 2013,which will be developed into a list of protected generic *** will be subjected to the XIXth International Botanical Congress in Shenzhen in July 2017 agreeing to a modification in the rules relating to protected lists,and scrutiny by procedures determined by the Nomenclature Committee for Fungi(NCF).The previously invalidly published generic names Barriopsis,Collophora(as Collophorina),Cryomyces,Dematiopleospora,Heterospora(as Heterosporicola),Lithophila,Palmomyces(as Palmaria)and Saxomyces are validated,as are two previously invalid family names,Bartaliniaceae and *** species of Lalaria,which were invalidly published are trans

关键词： Article 59 Classification One name Pleomorphic fungi Taxonomy

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Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

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Nature communications 2021年第1期12卷 3001页

作者： Cathrine Axfors Andreas M Schmitt Perrine Janiaud Janneke Van't Hooft Sherief Abd-elsalam ehab F Abdo Benjamin S Abella Javed Akram Ravi K Amaravadi Derek C Angus Yaseen M Arabi Shehnoor Azhar Lindsey R Baden Arthur W Baker Leila Belkhir Thomas Benfield Marvin A H Berrevoets Cheng-Pin Chen Tsung-Chia Chen Shu-Hsing Cheng Chien-Yu Cheng Wei-Sheng Chung Yehuda Z Cohen Lisa N Cowan Olav Dalgard Fernando F de Almeida e Val Marcus V G de Lacerda Gisely C de Melo Lennie Derde Vincent Dubee Anissa elfakir Anthony C Gordon Carmen M Hernandez-Cardenas Thomas Hills Andy I M Hoepelman Yi-Wen Huang Bruno Igau Ronghua Jin Felipe Jurado-Camacho Khalid S Khan Peter G Kremsner Benno Kreuels Cheng-Yu Kuo Thuy Le Yi-Chun Lin Wu-Pu Lin Tse-Hung Lin Magnus Nakrem Lyngbakken Colin McArthur Bryan J McVerry Patricia Meza-Meneses Wuelton M Monteiro Susan C Morpeth Ahmad Mourad Mark J Mulligan Srinivas Murthy Susanna Naggie Shanti Narayanasamy Alistair Nichol Lewis A Novack Sean M O'Brien Nwora Lance Okeke Léna Perez Rogelio Perez-Padilla Laurent Perrin Arantxa Remigio-Luna Norma e Rivera-Martinez Frank W Rockhold Sebastian Rodriguez-Llamazares Robert Rolfe Rossana Rosa Helge Røsjø Vanderson S Sampaio Todd B Seto Muhammad Shahzad Shaimaa Soliman Jason e Stout Ireri Thirion-Romero Andrea B Troxel Ting-Yu Tseng Nicholas A Turner Robert J Ulrich Stephen R Walsh Steve A Webb Jesper M Weehuizen Maria Velinova Hon-Lai Wong Rebekah Wrenn Fernando G Zampieri Wu Zhong David Moher Steven N Goodman John P A Ioannidis Lars G Hemkens Meta-Research Innovation Center at Stanford (METRICS) Stanford University Stanford CA USA. Department for Women's and Children's Health Uppsala University Uppsala Sweden. Department of Clinical Research University Hospital Basel University of Basel Basel Switzerland. Department of Medical Oncology University of Basel Basel Switzerland. Amsterdam University Medical Center Amsterdam University Amsterdam the Netherlands. Tropical Medicine and Infectious Diseases Department Faculty of Medicine Tanta University Tanta Egypt. Tropical Medicine and Gastroenterology Department Faculty of Medicine Assiut University Assiut Egypt. Department of Emergency Medicine University of Pennsylvania Philadelphia PA USA. Department of Internal Medicine Vice Chancellor University of Health Sciences Lahore Punjab Pakistan. Abramson Cancer Center and Department of Medicine University of Pennsylvania Philadelphia PA USA. Department of Critical Care Medicine The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center University of Pittsburgh Pittsburgh PA USA. the UPMC Health System Office of Healthcare Innovation University of Pittsburgh Medical Centre Pittsburgh PA USA. Intensive Care Department King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center Riyadh Saudi Arabia. Department of Public Health University of Health Sciences Lahore Punjab Pakistan. Division of Infectious Diseases Brigham and Women's Hospital Boston MA USA. Department of Medicine Division of Infectious Diseases and International Health Duke University Medical Center Durham NC USA. Infectious Diseases Department Cliniques universitaires Saint-Luc Université Catholique de Louvain Brussels Belgium. Center of Research & Disruption of Infectious Diseases Department of Infectious Diseases Copenhagen University Hospital Amager and Hvidovre Hvidovre Denmark. Department of Internal Medicine Elisabeth-Tweesteden hospital Ti

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26th Annual Computational Neuroscience Meeting (CNS*2017) of the Organization for Computational Neuroscience Antwerp, Belgium, July 15-20, 2017

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BMC NeUROscience 2017年第SUPPL 1期18卷 59-59页

作者： [Anonymous] Indiana University Purdue University Indianapolis Indianapolis IN 46032 USA Stark Neurosciences Research Institute Indiana University School of Medicine Indianapolis IN 46032 USA Department of Mathematics East Carolina University Greenville NC 27858 USA Jülich Supercomputing Centre Forschungszentrum Jülich 52425 Jülich Germany Future Systems Swiss National Supercomputing Centre 8092 Zurich Switzerland User Engagement and Support Swiss National Supercomputing Centre 6900 Lugano Switzerland Institut de Neurosciences des Systèmes Aix Marseille Univ 13005 Marseille France Simulation Lab Neuroscience Forschungszentrum Jülich Jülich Germany Department of Experimental Psychology Ghent University 9000 Ghent Belgium Donders Center for Cognitive Neuroimaging Radboud University 6525HR Nijmegen The Netherlands Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO 80309 USA Department of Neurosurgery Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Neurology Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Otolaryngology Johns Hopkins School of Medicine Baltimore MD 21287 USA INSERM U968 Paris France Sorbonne Universités UPMC University Paris 06 UMR_S 968 Institut de la Vision Paris France CNRS UMR_7210 Paris France Department of Computer Architecture and Technology University of Granada (CITIC) Granada Spain Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Institut de la Vision Paris France Department of Adaptive Machine Systems Osaka University Osaka Japan Department of Computer Science University of Cergy-Pontoise Cergy-Pontoise France Department of Physics and Astronomy College of Charleston Charleston SC 29424 USA School of Physics Faculty of Science University of Sydney Sydney NSW 2006 Australia Center of Excellence for Integrative Brain Function Australian Research Council Sydney Australia Max Planck Institute for Human Cognitive and Brain Sciences Saxony Lei

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