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Identifying and Anticipating Cyberattacks That Could Cause Physical Damage to Industrial Control systems

IEEE Power and Energy Technology systems Journal 2019年第4期6卷 172-182页

作者： Angle, Matthew G. Madnick, Stuart Kirtley, James L. Khan, Shaharyar Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology CambridgeMA02139 United States Sloan School of Management School of Engineering Massachusetts Institute of Technology CambridgeMA02139 United States System Design and Management Program Massachusetts Institute of Technology CambridgeMA02139 United States

Physical control systems are increasingly controlled by reconfigurable, network-enabled devices to increase flexibility and ease commissioning and maintenance. Such capability creates vulnerabilities. Devices may be remotely reprogrammed by a malicious actor to act in unintended ways, causing physical damage to mechanical equipment, infrastructure, and life and limb. In this paper, past examples of actual damage to cyber-physical systems are shown, threats posed by software-controlled variable frequency drives (VFDs) are analyzed, and a small-scale version of an attack on ubiquitous VFD equipment is demonstrated. © 2014 IEEE.

关键词： Embedded systems

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Cavity-mediated superthermal phonon correlations in the ultrastrong coupling regime

arXiv

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arXiv 2024年

作者： Kim, Dasom Hou, Jin Lee, Geon Agrawal, Ayush Kim, Sunghwan Zhang, Hao Bao, Di Baydin, Andrey Wu, Wenjing Tay, Fuyang Huang, Shengxi Chia, Elbert E.M. Kim, Dai-Sik Seo, Minah Mohite, Aditya D. Hagenmüller, David Kono, Junichiro Applied Physics Graduate Program Smalley–Curl Institute Rice University HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Department of Materials Science and NanoEngineering Rice University HoustonTX77005 United States Sensor System Research Center Korea Institute of Science and Technology Seoul02792 Korea Republic of Department of Physics and Astronomy Seoul National University Seoul08826 Korea Republic of Department of Chemical and Biomolecular Engineering Rice University Houston77005 United States Ulsan44919 Korea Republic of Division of Physics and Applied Physics School of Physical and Mathematical Sciences Nanyang Technological University Singapore637371 Singapore Smalley–Curl Institute Rice University HoustonTX77005 United States Rice Advanced Materials Institute Rice University HoustonTX77005 United States KU–KIST Graduate School of Converging Science and Technology Korea University Seoul02841 Korea Republic of Université de Strasbourg CNRS Strasbourg67200 France Department of Physics and Astronomy Rice University HoustonTX77005 United States

Phonons, or vibrational quanta, are behind some of the most fundamental physical phenomena in solids, including superconductivity, Raman processes, and broken-symmetry phases. It is therefore of fundamental importance to find ways to harness phonons for controlling these phenomena and developing novel quantum technologies. However, the majority of current phonon control techniques rely on the use of intense external driving fields or strong anharmonicities, which restricts their range of applications. Here, we present a scheme for controlling the intensity fluctuations in phonon emission at room temperature based on multimode ultrastrong light–matter coupling. The multimode ultrastrong coupling regime is achieved by coupling two optical phonon modes in lead halide perovskites to an array of nanoslots, which operates as a single-mode cavity. The extremely small mode volume of the nanoslots enables unprecedented coupling strengths in a cavity phonon-polariton system. In the far-detuned, low-cavity-frequency regime, we demonstrate that the nanoslot resonator mediates an effective coupling between the phonon modes, resulting in superthermal phonon bunching in thermal equilibrium, both within the same mode and between different modes. Experimental results are in good agreement with a multimode Hopfield model. Our work paves the way for the tailoring of phonons to modify charge and energy transport in perovskite materials, with potential applications in light-collecting or emitting devices. Copyright © 2024, The Authors. All rights reserved.

关键词： Perovskite

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A pretrained transformer model for decoding individual glucose dynamics from continuous glucose monitoring data

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National science Review 2025年第5期 362-381页

作者： Yurun Lu Dan Liu Zhongming Liang Rui Liu Pei Chen Yitong Liu Jiachen Li Zhanying Feng Lei M.Li Bin Sheng Weiping Jia Luonan Chen Huating Li Yong Wang Center for Excellence in Mathematical Sciences National Center for Mathematics and Interdisciplinary Sciences Hua Loo-Keng Center for Mathematical Sciences Key Laboratory of Management Decision and Information System Academy of Mathematics and Systems ScienceChinese Academy of Sciences School of Mathematics University of Chinese Academy of SciencesChinese Academy of Sciences Department of Endocrinology and Metabolism Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai Diabetes InstituteShanghai Clinical Center for Diabetes Shanghai Key Laboratory of Diabetes Mellitus Key Laboratory of Systems Health Science of Zhejiang Province School of Life ScienceHangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences BGI-Research School of Mathematics South China University of Technology Department of Statistics Department of Biomedical Data Science Bio-X ProgramStanford University Department of Computer Science and Engineering Shanghai Jiao Tong University State Key Laboratory of Cell Biology Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences Guangdong Institute of Intelligence Science and Technology Pazhou Laboratory (Huangpu)

Continuous glucose monitoring(CGM) technology has grown rapidly to track real-time blood glucose levels and trends with improved sensor accuracy. The ease of use and wide availability of CGM will facilitate safe and effective decision making for diabetes management. Here, we developed an attention-based deep learning model, CGMformer, pretrained on a well-controlled and diverse corpus of CGM data to represent individual's intrinsic metabolic state and enable clinical applications. During pretraining, CGMformer encodes glucose dynamics including glucose level, fluctuation, hyperglycemia, and hypoglycemia into latent space with self-supervised learning. It shows generalizability in imputing glucose value across five external datasets with different populations and metabolic states(MAE = 3.7 mg/d L). We then fine-tuned CGMformer towards a diverse panel of downstream tasks in the screening of diabetes and its complications using task-specific data, which demonstrated a consistently boosted predictive accuracy over direct fine-tuning on a single task(AUROC = 0.914 for type 2 diabetes(T2D) screening and 0.741 for complication screening). By learning an intrinsic representation of an individual's glucose dynamics,CGMformer classifies non-diabetic individuals into six clusters with elevated T2D risks, and identifies a specific cluster with lean body-shape but high risk of glucose metabolism disorders, which is overlooked by traditional glucose measurements. Furthermore, CGMformer achieves high accuracy in predicting an individual's postprandial glucose response with dietary modelling(Pearson correlation coefficient = 0.763)and helps personalized dietary recommendations. Overall, CGMformer pretrains a transformer neural network architecture to learn an intrinsic representation by borrowing information from a large amount of daily glucose profiles, and demonstrates predictive capabilities fine-tuned towards a broad range of downstream applications, holding promise for the ear

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Implementation of Mobile game for Religion Learning

Implementation of Mobile game for Religion Learning

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2019 IEEE International Conference on engineering, Technology and Education, TALE 2019

作者： Sulistiyo, Edy Vindy Anwar, Nizirwan Warnars, Diana Teresia Spits Wibawa, Setya Chendra Brotosaputro, Goenawan Kristiadi, Dedy Prasetya Warnars, Harco Leslie Hendric Spits Hashimoto, Kiyota Universitas Negeri Surabaya Electrical Engineering Department Jawa Timur60213 Indonesia School of Computer Science Bina Nusantara University Game Application Technology Program Jakarta11480 Indonesia Esa Unggul University Faculty of Computer Science Jakarta11510 Indonesia Bina Nusantara University Information Systems Department Jakarta11480 Indonesia Universitas Budi Luhur Information System Department Jakarta12260 Indonesia Raharja University Computer Science Department Tangerang15117 Indonesia Binus Graduate Program - Doctor of Computer Science Bina Nusantara University Computer Science Department Jakarta11480 Indonesia Prince Songkla University Faculty of Technology and Environment Phuket Campus Thailand

ISBN: (纸本)9781728126654

Currently, the growth of information and technology is rapid. It makes a lot of things in various fields including education becoming more effective and efficient. In education, one of its implementation which is a game is proven to be a useful tool to support conventional teaching methods and bring a more natural understanding of learning materials. Moreover, as a product of the popular culture in modern society, video game mirrors the general culture practice in real life and reflects it via its own culture inside the game. This makes a video game can give a contribution to the social construction of reality as it affects the player's view towards learning in real life and vice versa. From there, we see that there is an opportunity for learning about religion to be supported by its utilization to provide an interactive and fun learning experience. In this paper, we discuss how a video game is implemented to support religious learning. The game was developed with the scrum method where we surveyed to gather the user requirements before the design step. The game design was made by using the use case diagram and storyboard, and it was built using Unity version 2017.3.0f3. © 2019 IEEE.

关键词： Serious games

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Complications in the ALMA detection of phosphine at Venus

arXiv

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arXiv 2021年

作者： Akins, Alex B. Lincowski, Andrew P. Meadows, Victoria S. Steffes, Paul G. Jet Propulsion Laboratory California Institute of Technology Instruments Division PasadenaCA91011 United States Department of Astronomy and Astrobiology Program University of Washington Box 351580 SeattleWA98195 United States NASA Nexus for Exoplanet System Science Virtual Planetary Laboratory Team University of Washington Box 351580 SeattleWA98195 United States School of Electrical and Computer Engineering Georgia Institute of Technology AtlantaGA30308 United States

Recently published ALMA observations suggest the presence of 20 ppb PH3 in the upper clouds of Venus. This is an unexpected result, as PH3 does not have a readily apparent source and should be rapidly photochemically destroyed according to our current understanding of Venus atmospheric chemistry. While the reported PH3 spectral line at 266.94 GHz is nearly co-located with an SO2 spectral line, the non-detection of stronger SO2 lines in the wideband ALMA data is used to rule out SO2 as the origin of the feature. We present a reassessment of wideband and narrowband datasets derived from these ALMA observations. The ALMA observations are re-reduced following both the initial and revised calibration procedures discussed by the authors of the original study. We also investigate the phenomenon of apparent spectral line dilution over varying spatial scales resulting from the ALMA antenna configuration. A 266.94 GHz spectral feature is apparent in the narrowband data using the initial calibration procedures, but this same feature can not be identified following calibration revisions. The feature is also not reproduced in the wideband data. While the SO2 spectral line is not observed at 257.54 GHz in the ALMA wideband data, our dilution simulations suggest that SO2 abundances greater than the previously suggested 10 ppb limit would also not be detected by ALMA. Additional millimeter, sub-millimeter, and infrared observations of Venus should be undertaken to further investigate the possibility of PH3 in the Venus atmosphere. © 2021, CC BY-NC-SA.

关键词： Antennas

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Fluctuating risk of acute kidney injury-related mortality for four weeks after exposure to air pollution: A multi-country time-series study in 6 countries

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Environment International 2024年 183卷 108367页

作者： Min, Jieun Kang, Duk-Hee Kang, Cinoo Bell, Michelle L. Kim, Ho Yang, Juyeon Gasparrini, Antonio Lavigne, Eric Hashizume, Masahiro Kim, Yoonhee Fook Sheng Ng, Chris Honda, Yasushi das Neves Pereira da Silva, Susana Madureira, Joana Leon Guo, Yue Pan, Shih-Chun Armstrong, Ben Sera, Francesco Masselot, Pierre Schwartz, Joel Maria Vicedo-Cabrera, Ana Pyo Lee, Jung Al-Aly, Ziyad Won Lee, Jung Kwag, Youngrin Ha, Eunhee Lee, Whanhee Department of Environmental Medicine College of Medicine Ewha Womans University Seoul Korea Republic of Graduate Program in System Health Science and Engineering College of Medicine Ewha Womans University Seoul Korea Republic of Division of Nephrology Department of Internal Medicine Ewha Womans University School of Medicine Ewha Medical Research Center Seoul Korea Republic of Department of Public Health Sciences Graduate School of Public Health Seoul National University Seoul Korea Republic of Yale School of the Environment Yale University New HavenCT United States Biostatistics Collaboration Unit Yonsei University College of Medicine Seoul Korea Republic of Lab Department of Public Health Environments and Society London School of Hygiene & Tropical Medicine London United Kingdom School of Epidemiology & Public Health Faculty of Medicine University of Ottawa Ottawa Canada Department of Global Health Policy Graduate School of Medicine The University of Tokyo Tokyo Japan Department of Global Environmental Health Graduate School of Medicine University of Tokyo Tokyo Japan School of Tropical Medicine and Global Health Nagasaki University Nagasaki Japan Center for Climate Change Adaptation National Institute for Environmental Studies Tsukuba Japan Department of Epidemiology Instituto Nacional de Saúde Dr. Ricardo Jorge Lisbon Portugal EPIUnit-Institute of Public Health University of Porto Porto Portugal Porto Portugal College of Medicine and NTU Hospital Taipei Taiwan National Institute of Environmental Health Science National Health Research Institutes Zhunan Taiwan Department of Public Health Environments and Society London School of Hygiene & Tropical Medicine London United Kingdom Department of Statistics Computer Science and Applications "G. Parenti" University of Florence Florence Italy Department of Environmental Health Harvard T.H. Chan School of Public Health BostonMA United States Institute of Social and Preventive Medicine Universi

Background: Recent studies have reported that air pollution is related to kidney diseases. However, the global evidence on the risk of death from acute kidney injury (AKI) owing to air pollution is limited. Therefore, we investigated the association between short-term exposure to air pollution—particulate matter ≤ 2.5 μm (PM2.5), ozone (O3), and nitrogen dioxide (NO2)—and AKI-related mortality using a multi-country dataset. Methods: This study included 41,379 AKI-related deaths in 136 locations in six countries during 1987–2018. A novel case time-series design was applied to each air pollutant during 0–28 lag days to estimate the association between air pollution and AKI-related deaths. Moreover, we calculated AKI deaths attributable to non-compliance with the World Health Organization (WHO) air quality guidelines. Results: The relative risks (95% confidence interval) of AKI-related deaths are 1.052 (1.003, 1.103), 1.022 (0.994, 1.050), and 1.022 (0.982, 1.063) for 5, 10, and 10 µg/m3 increase in lag 0–28 days of PM2.5, warm-season O3, and NO2, respectively. The lag-distributed association showed that the risk appeared immediately on the day of exposure to air pollution, gradually decreased, and then increased again reaching the peak approximately 20 days after exposure to PM2.5 and O3. We also found that 1.9%, 6.3%, and 5.2% of AKI deaths were attributed to PM2.5, warm-season O3, and NO2 concentrations above the WHO guidelines. Conclusions: This study provides evidence that public health policies to reduce air pollution may alleviate the burden of death from AKI and suggests the need to investigate the several pathways between air pollution and AKI death. © 2023 The Author(s)

关键词： Air quality

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Alert and Response of Earthquake and Tsunami for Community Based Disaster Risk Reduction

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Journal of Physics: Conference Series 2021年第1期1811卷

作者： Rr M I Retno Susilorini Andre Kurniawan Pamudji Ridwan Sanjaya Amrizarois Ismail Ardhito Hayyu Amasto Department of Infrastructure and Environmental Engineering Faculty of Environmental Science and Technology Soegijapranata Catholic University Semarang Master Program of Environmental and Urban Studies Faculty of Environmental Science and Technology Soegijapranata Catholic University Semarang Department of Information System Faculty of Computer Science Soegijapranata Catholic University Semarang

Indonesia had been suffered by earthquake and tsunami for many centuries. Since many lives have taken by tsunami strikes, alert and response system are very important as important part of Disaster Risk Reduction, especially in area with high population density. This research conducted in Kangkung fishing village in Bandar Lampung coastal area which is an earthquake and tsunami prone area. The aim of the research is to study alert and response of Community Based Disaster Risk Reduction. The research conducted by qualitative method and purposive-descriptive approach. There were 53 respondents which participated in the survey and interview. It is reported that 'Smart Resilient City' model suitable for community needs of alert and response of earthquake and tsunami disaster. This research meets conclusion that 'Smart Resilient City' model may become a great solution in Community Based Disaster Risk Reduction to cope with the hazard of earthquake and tsunami comprehensively and sustainably.

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The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions

arXiv

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arXiv 2023年

作者： Ma, Jun Xie, Ronald Ayyadhury, Shamini Ge, Cheng Gupta, Anubha Gupta, Ritu Gu, Song Zhang, Yao Lee, Gihun Kim, Joonkee Lou, Wei Li, Haofeng Upschulte, Eric Dickscheid, Timo de Almeida, José Guilherme Wang, Yixin Han, Lin Yang, Xin Labagnara, Marco Gligorovski, Vojislav Scheder, Maxime Rahi, Sahand Jamal Kempster, Carly Pollitt, Alice Espinosa, Leon Mignot, Tâm Middeke, Jan Moritz Eckardt, Jan-Niklas Li, Wangkai Li, Zhaoyang Cai, Xiaochen Bai, Bizhe Greenwald, Noah F. Van Valen, David Weisbart, Erin Cimini, Beth A. Cheung, Trevor Brück, Oscar Bader, Gary D. Wang, Bo Peter Munk Cardiac Centre University Health Network TorontoON Canada Department of Laboratory Medicine and Pathobiology University of Toronto TorontoON Canada Vector Institute TorontoON Canada Department of Molecular Genetics University of Toronto TorontoON Canada Donnelly Centre University of Toronto TorontoON Canada Princess Margaret Cancer Centre University Health Network TorontoON Canada School of Medicine and Pharmacy Ocean University of China Qingdao China New Delhi India Laboratory Oncology Dr. BRA-IRCH All India Institute of Medical Sciences New Delhi India Department of Image Reconstruction Nanjing Anke Medical Technology Co. Ltd. Nanjing China Shanghai Artificial Intelligence Laboratory Shanghai China Graduate School of AI KAIST Seoul Korea Republic of Shenzhen Research Institute of Big Data Shenzhen China Shenzhen China Helmholtz AI Research Center Jülich Jülich Germany Faculty of Mathematics and Natural Sciences Institute of Computer Science Heinrich Heine University Düsseldorf Düsseldorf Germany Hinxton United Kingdom Champalimaud Foundation - Centre for the Unknown Lisbon Portugal Department of Bioengineering Stanford University Palo AltoCA United States Tandon School of Engineering New York University New YorkNY United States School of Biomedical Engineering Health Science Center Shenzhen University Shenzhen China Lausanne Switzerland School of Biological Sciences University of Reading Reading United Kingdom Laboratoire de Chimie Bactérienne CNRS Université Aix Marseille UMR Institut de Microbiologie de la Méditerranée Marseille France Department of Internal Medicine I University Hospital Dresden Technical University Dresden Dresden Germany Else Kroener Fresenius Center for Digital Health Technical University Dresden Dresden Germany Department of Automation University of Science and Technology of China Hefei China Institute of Advanced Technology University of Science and Technology of China Hefei Chi

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in different experimental settings. Here, we present a multi-modality cell segmentation benchmark, comprising over 1500 labeled images derived from more than 50 diverse biological experiments. The top participants developed a Transformer-based deep-learning algorithm that not only exceeds existing methods but can also be applied to diverse microscopy images across imaging platforms and tissue types without manual parameter adjustments. This benchmark and the improved algorithm offer promising avenues for more accurate and versatile cell analysis in microscopy imaging. © 2023, CC BY-NC-ND.

关键词： Deep learning

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Separation of mitochondrial diseased cells based on organelle-level difference using a dep microfluidic system 23

Separation of mitochondrial diseased cells based on organell...

引用

23rd International Conference on Miniaturized systems for Chemistry and Life sciences, MicroTAS 2019

作者： Chi, Pei-Yin Chuang, Ting-Wei Chu, Tzu-Tsai Kuo, Chia-Tzu Wu, Yu-Ting Farmehini, Vahid Shieh, Dar-Bin Tseng, Fan-Gang Wei, Yau-Huei Swami, Nathan Chou, Chia-Fu Nano Science and Technology Program TIGP Academia Sinica Taipei Taiwan Institute of Physics Academia Sinica Taipei Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu Taiwan Center for Mitochondrial Medicine Free Radical Research Changhua Christian Hospital Changhua Taiwan Department of Electrical and Computer Engineering University of Virginia Charlottesville United States Institute of Oral Medicine School of Medicine National Cheng-Kung University Tainan Taiwan

ISBN: (纸本)9781733419000

It is imperative to develop tools to characterize cells with the diseased and normal mitochondria to monitor the healthiness of cells and take preventive measures for potential mitochondrial disease development. Here, we adopt insulator dielectrophoresis (i-DEP), by utilizing the intrinsic dielectric response of a cell to an external AC electric field to differentiate cells, containing partially diseased and normal mitochondria. Taking advantage of dielectrophoresis, DEP, principle, we developed a quick diagnostic method to detect mitochondrial disease in living cells, which is not readily achievable by conventional cell cytometry. © 2019 CBMS-0001.

关键词： Electrophoresis

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Hamiltonian Hopping for Efficient Chiral Mode Switching in Encircling Exceptional Points

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Physical Review Letters 2020年第18期125卷 187403-187403页

作者： Aodong Li Jianji Dong Jian Wang Ziwei Cheng John S. Ho Dawei Zhang Jing Wen Xu-Lin Zhang C. T. Chan Andrea Alù Cheng-Wei Qiu Lin Chen Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 China Department of Electrical and Computer Engineering National University of Singapore Singapore 117583 Singapore Engineering Research Center of Optical Instrument and Systems Ministry of Education and Shanghai Key Lab of Modern Optical System University of Shanghai for Science and Technology No. 516 Jungong Road Shanghai 200093 China State Key Laboratory of Integrated Optoelectronics College of Electronic Science and Engineering Jilin University Changchun 130012 China Department of Physics The Hong Kong University of Science and Technology Clear Water Bay Hong Kong 999077 China Photonics Initiative Advanced Science Research Center City University of New York New York New York 10031 USA Physics Program Graduate Center City University of New York New York New York 10016 USA

Dynamically encircling exceptional points (EPs) can lead to chiral mode switching as the system parameters are varied along a path that encircles EP. However, conventional encircling protocols result in low transmittance due to path-dependent losses. Here, we present a paradigm to encircle EPs that includes fast Hamiltonian variations on the parameter boundaries, termed Hamiltonian hopping, enabling ultrahigh-efficiency chiral mode switching. This protocol avoids path-dependent loss and allows us to experimentally demonstrate nearly 90% efficiency at 1550 nm in the clockwise direction, overcoming a long-standing challenge of non-Hermitian optical systems and powering up new opportunities for EP physics.

关键词： Open quantum systems & decoherence PT-symmetric quantum mechanics Photonics Waveguides

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