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A computational framework for longitudinal medication adherence prediction in breast cancer survivors: A social cognitive theory based approach

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arXiv 2025年

作者： Kaur, Navreet Gonzales, Manuel Alcaraz, Cristian Garcia Gong, Jiaqi Wells, Kristen J. Barnes, Laura E. Department of Systems and Information Engineering University of Virginia CharlottesvilleVA United States SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology San DiegoCA United States Department of Computer Science The University of Alabama TuscaloosaAL United States Department of Psychology San Diego State University San DiegoCA United States

Non-adherence to medications is a critical concern since nearly half of patients with chronic illnesses do not follow their prescribed medication regimens, leading to increased mortality, costs, and preventable human distress. Amongst stage 0-3 breast cancer survivors, adherence to long-term adjuvant endocrine therapy (i.e., Tamoxifen and aromatase inhibitors) is associated with a significant increase in recurrence-free survival. This work aims to develop multi-scale models of medication adherence to understand the significance of different factors influencing adherence across varying time frames. We introduce a computational framework guided by Social Cognitive Theory for multi-scale (daily and weekly) modeling of longitudinal medication adherence. Our models employ both dynamic medication-taking patterns in the recent past (dynamic factors) as well as less frequently changing factors (static factors) for adherence prediction. Additionally, we assess the significance of various factors in influencing adherence behavior across different time scales. Our models outperform traditional machine learning counterparts in both daily and weekly tasks in terms of both accuracy and specificity. Daily models achieved an accuracy of 87.25% (Precision – 92.04%, Recall – 93.15%, Specificity – 77.50%), and weekly models, an accuracy of 76.04% (Precision – 75.83%, Recall – 85.80%, Specificity – 72.30%). Notably, dynamic past medication-taking patterns prove most valuable for predicting daily adherence, while a combination of dynamic and static factors is significant for macro-level weekly adherence patterns. While our models exhibit strong predictive performance, they are constrained by potential cohort-specific biases, reliance on self-reported adherence data, and a limited understanding of the context around non-adherence. Future research will focus on external validation across diverse populations and explore the real-world implementation of sensor-rich systems for a more compre

关键词： Endocrinology

Deep Learning in Smart Healthcare: A GAN-based Approach for Imbalanced Alzheimer's Disease Classification

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Procedia computer science 2024年 241卷 146-153页

作者： Hina Tufail Abdul Ahad Ira Puspitasari Ibraheem Shayea Paulo Jorge Coelho Ivan Miguel Pires Department of Computer Science University of Management and Technology Sialkot Pakistan Information System Study Program Faculty of Science and Technology Universitas Airlangga School of Software Northwestern Polytechnical University Xian Shaanxi P.R. China Department of Electronics and Communication Engineering Istanbul Technical University(ITU) Turkey Polytechnic University of Leiria Leiria Portugal Institute for Systems Engineering and Computers at Coimbra (INESC Coimbra) Coimbra Portugal Instituto de Telecomunicações Escola Superior de Tecnologia e Gestão de Águeda Universidade de Aveiro Águeda Portugal

Alzheimer's disease (AD) is a type of dementia that leads to memory loss and impairment, which afects patients’ lives badly. It is not curable yet, but its progression can be slowed down if detected at earlier stages. In this research study, we propose a transfer learning-based convolutional neural network (CNN) model to classify magnetic resonance imaging (MRI) into one of four stages of Alzheimer's disease. One of the major limitations of the deep learning-based classification model is the non-availability of healthcare datasets related to AD. The widely used Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset has a major class imbalance issue. We propose a generative adversarial network (GAN) based data augmentation technique to overcome the data imbalance. This promotes the investigation of applying GANs to generate synthetic samples for minority classes in Alzheimer's disease datasets to enhance classification performance. The results show the progression in the overall classification process of AD.

关键词： Alzheimer disease (AD) Deep learning Convolutional Neural Network (CNN) computer-aided diagnosis (CAD)

Synthetic helicoidal rotation of a quasielectrostatic ring resonator for ultrabroadband magnet-free nonreciprocity

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Physical Review Applied 2024年第6期22卷 064020-064020页

作者： Aravind Nagulu Ahmed Mekawy Mykhailo Tymchenko Dimitrios Sounas Harish Krishnaswamy Andrea Alù Department of Electrical and Systems Engineering Washington University in St. Louis St. Louis Missouri 63130 USA Photonics Initiative Advanced Science Research Center City University of New York New York New York 10031 USA Department of Electrical and Computer Engineering The University of Texas at Austin Austin Texas 78712 USA Department of Electrical Engineering Wayne State University Detroit Michigan 48202 USA Department of Electrical Engineering Columbia University New York New York 10027 USA Physics Program Graduate Center City University of New York New York New York 10016 USA

Suitably tailored forms of spatiotemporal modulation in electronic circuit networks have been recently employed to overcome fundamental challenges in modern electronic systems, including breaking reciprocity, squeezing the footprint of high-Q resonators, and overcoming the delay-bandwidth limit. Rotating patterns of temporal modulations have been used to synthesize angular momentum, which replaces magnetic bias to break reciprocity in integrated circuits. However, this approach is limited by trade-offs between modulation speed, footprint, and bandwidth of operation. Rotating switching patterns in commutated capacitor networks also enables compact filters and quasielectrostatic wave propagation, overcoming the delay-bandwidth limit. In this paper, we combine these mechanisms in an integrated-circuit ring that synthetically rotates in two dimensions, realizing an effective helicoidal motion that provides ultrabroadband quasielectrostatic nonreciprocal responses fitting within a theoretically infinitesimal size. We also analyze the impact of modulation signal noise on time-modulated nonreciprocal components and unveil the role of a dynamic noise mechanism based on which the noise level increases in the presence of a strong signal passing through the component, along with methods to mitigate this effect. We experimentally verify these principles in a three-port integrated circulator based on a 65-nm CMOS process that operates from dc to 1 GHz with a miniaturization factor of 2 × 106.

关键词： Metamaterials Non-reciprocal transmission Photonics Topolectrical circuits

Trackable Agent-based Evolution Models at Wafer Scale

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arXiv 2024年

作者： Moreno, Matthew Andres Yang, Connor Dolson, Emily Zaman, Luis Department of Ecology and Evolutionary Biology University of Michigan Ann Arbor United States Center for the Study of Complex Systems University of Michigan Ann Arbor United States Michigan Institute for Data Science University of Michigan Ann Arbor United States Undergraduate Research Opportunities Program University of Michigan Ann Arbor United States Department of Computer Science and Engineering Michigan State University East Lansing United States Program in Ecology Evolution and Behavior Michigan State University East Lansing United States

Continuing improvements in computing hardware are poised to transform capabilities for in silico modeling of cross-scale phenomena underlying major open questions in evolutionary biology and artificial life, such as transitions in individuality, eco-evolutionary dynamics, and rare evolutionary events. Emerging ML/AI-oriented hardware accelerators, like the 850,000 processor Cerebras Wafer Scale Engine (WSE), hold particular promise. However, many practical challenges remain in conducting informative evolution experiments that efficiently utilize these platforms’ large processor counts. Here, we focus on the problem of extracting phylogenetic information from agent-based evolution on the WSE platform. This goal drove significant refinements to decentralized in silico phylogenetic tracking, reported here. These improvements yield order-of-magnitude performance improvements. We also present an asynchronous island-based genetic algorithm (GA) framework for WSE hardware. Emulated and on-hardware GA benchmarks with a simple tracking-enabled agent model clock upwards of 1 million generations a minute for population sizes reaching 16 million agents. This pace enables quadrillions of agent replication events a day. We validate phylogenetic reconstructions from these trials and demonstrate their suitability for inference of underlying evolutionary conditions. In particular, we demonstrate extraction, from wafer-scale simulation, of clear phylometric signals that differentiate runs with adaptive dynamics enabled versus disabled. Together, these benchmark and validation trials reflect strong potential for highly scalable agent-based evolution simulation that is both efficient and observable. Developed capabilities will bring entirely new classes of previously intractable research questions within reach, benefiting further explorations within the evolutionary biology and artificial life communities across a variety of emerging high-performance computing platforms. Copyright © 20

关键词： Genetic algorithms

IoT Attack Detection and Prevention Through Machine Learning System

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IoT Attack Detection and Prevention Through Machine Learning...

Communication, Security and Artificial Intelligence (ICCSAI), International Conference on

作者： Kanishk Agrawal Pavan Kumar Reddy Poli Yash Gupta Garv Juneja Adhip Kishen Bopaiah Dinesh Ashok Arani Department of IET CSE Manglayatan University Aligarh Uttar Pradesh India Managing Information Technology Implementations Program management for fortune 6 Healthcare Company USA Department of Computer Science and Information Systems Birla Institute of Technology and Science Pilani India Department of Computer Science and Engineering Maharaja Surajmal Institute of Technology Guru Gobind Singh Indraprastha University Delhi India ICT Trainer Trinity College Bangalore India Manglayatan University Aligarh Uttar Pradesh India

Attacks on web applications are constantly growing in both frequency and severity. Abundant data on the internet stimulates hackers to attempt different types of cyberattacks. Attack detection using conventional approaches and outdated data processing techniques has become outmoded as a result of this development. The purpose of this study is to investigate IoT attacks and discuss the efficient ML technique implementation strategies for restricting security risks. Among different security techniques, Machine learning (ML) systems demonstrated commendable feasibility in improving network and device security for the Internet of Things. The study with contextual research recognises and comprehends that modified “Support Vector Machine (SVM)” as well as “Random Forest (RF)” ML techniques showed optimal performance in IoT attack detection and prevention.

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Preprocessing Techniques for Enhancing Vision-Based Detection System for Tire Sidewall Extraction

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Preprocessing Techniques for Enhancing Vision-Based Detectio...

International Seminar on Research of Information Technology and Intelligent systems (ISRITI)

作者： Jia Hao Loo Veronica Lestari Jauw Chin Seong Lim Khairul-Rijal Sarmin Nunung Nurul Qomariyah Ahmad Nurul Fajar Department of Mechanical Materials and Manufacturing Engineering University of Nottingham Malaysia Malaysia Continental Tyre Technology Centre Malaysia Petaling Jaya Malaysia Computer Science Department School of Computing and Creative Arts Bina Nusantara University Jakarta Indonesia Information System Management Department BINUS Graduate Program-Master Information Systems Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331519643

ISBN: (纸本)9798331519650

This study aims to develop a system for extracting crucial information from tire sidewalls using Optical Character Recognition (OCR). Initially, images of tire were captured manually by smartphone cameras, including Redmi 9T, iPhone 11, and Galaxy S23 Ultra. The captured images are then transferred to a computer for storage. Subsequently, these images were cropped according to the boundaries identified by Hough Circle Transform (HCT). The cropped images were then further pre-processed. During the pre-processing phase, geometrical transformation and image sharpening techniques are applied to enhance the clarity and readability of the text images. The text is then extracted using Google Vision, with the extracted text categorized by size, DOT, brand and pattern. The results indicated that the effectiveness of image pre-processing was constrained by the accuracy of circle detection, which reached a maximum rate of 87.1%. This causes parts of the text to be cut out inaccurately, leading to a suboptimal extraction accuracy of 55.65%. It is also observed that the Redmi 9T camera produced inconsistent results compared to other devices. Specifically, the iPhone 11 and Samsung Galaxy S23 Ultra demonstrated superior extraction accuracies of 69.71% and 66.37%, respectively, whereas the Redmi 9T achieved a lower extraction accuracy of 37.76%.

关键词： Accuracy Optical character recognition Text categorization Lighting Transforms US Department of Transportation Cameras Tires Internet Data mining

Diffusion-based Reinforcement Learning for Edge-enabled AI-Generated Content Services

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TechRxiv

TechRxiv 2023年

作者： Du, Hongyang Li, Zonghang Niyato, Dusit Kang, Jiawen Xiong, Zehui Huang, Huawei Mao, Shiwen School of Computer Science and Engineering The Energy Research Institute @ NTU Interdisciplinary Graduate Program Nanyang Technological University Singapore School of Information and Communication Engineering University of Electronic Sciences and Technology of China Chengdu China School of Automation Guangdong University of Technology China Pillar of Information Systems Technology and Design Singapore University of Technology and Design Singapore School of Software Engineering Sun Yat-Sen University Zhuhai China Department of Electrical and Computer Engineering Auburn University Auburn United States

As Metaverse emerges as the next-generation Internet paradigm, the ability to efficiently generate content is paramount. AI-Generated Content (AIGC) emerges as a key solution, yet the resource-intensive nature of large Generative AI (GAI) models presents challenges. To address this issue, we introduce an AIGC-as-a-Service (AaaS) architecture, which deploys AIGC models in wireless edge networks to ensure broad AIGC services accessibility for Metaverse users. Nonetheless, an important aspect of providing personalized user experiences requires carefully selecting AIGC Service Providers (ASPs) capable of effectively executing user tasks, which is complicated by environmental uncertainty and variability. Addressing this gap in current research, we introduce the AI-Generated Optimal Decision (AGOD) algorithm, a diffusion model-based approach for generating the optimal ASP selection decisions. Integrating AGOD with Deep Reinforcement Learning (DRL), we develop the Deep Diffusion Soft Actor-Critic (D2SAC) algorithm, enhancing the efficiency and effectiveness of ASP selection. Our comprehensive experiments demonstrate that D2SAC outperforms seven leading DRL algorithms. Furthermore, the proposed AGOD algorithm has the potential for extension to various optimization problems in wireless networks, positioning it as a promising approach for future research on AIGC-driven services. The implementation of our proposed method is available at: https://***/Lizonghang/AGOD. © 2023, CC BY.

关键词： Reinforcement learning

Diffusion-based Reinforcement Learning for Edge-enabled AI-Generated Content Services

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arXiv 2023年

作者： Du, Hongyang Li, Zonghang Niyato, Dusit Kang, Jiawen Xiong, Zehui Huang, Huawei Mao, Shiwen The School of Computer Science and Engineering The Energy Research Institute @ NTU Interdisciplinary Graduate Program Nanyang Technological University Singapore The School of Information and Communication Engineering University of Electronic Sciences and Technology of China Chengdu China The School of Automation Guangdong University of Technology China The Pillar of Information Systems Technology and Design Singapore University of Technology and Design Singapore The School of Software Engineering Sun Yat-Sen University Zhuhai China The Department of Electrical and Computer Engineering Auburn University Auburn United States

关键词： Reinforcement learning

Heterogeneous download times in bandwidth-homogeneous BitTorrent swarms

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arXiv 2021年

作者： Murai, Fabricio De Rocha, Antonio A.A. Figueiredo, Daniel R. De Souza E Silva, Edmundo A. COPPE/Systems Engineering and Computer Science Program Federal University of Rio de Janeiro Rio de Janeiro Brazil Computer Science Department Fluminense Federal University Niterói Brazil

Modeling and understanding BitTorrent (BT) dynamics is a recurrent research topic mainly due to its high complexity and tremendous practical efficiency. Over the years, different models have uncovered various phenomena exhibited by the system, many of which have direct impact on its performance. In this paper we identify and characterize a phenomenon that has not been previously observed: homogeneous peers (with respect to their upload capacities) experience heterogeneous download times. This behavior has direct impact on peer and system performance, such as high variability of download times, unfairness with respect to peer arrival order, bursty departures and content synchronization. Detailed packet-level simulations and prototype-based experiments on the Internet were performed to characterize this phenomenon. We also develop a mathematical model that accurately predicts the heterogeneous download rates of the homogeneous peers as a function of their content. In addition, we apply the model to calculate lower and upper bounds to the number of departures that occur in a burst. The heterogeneous download rates are more prevalent in unpopular swarms (very few peers). Although few works have addressed this kind of swarm, these by far represent the most common type of swarm in BT. © 2021, CC BY.

关键词： Functions