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Citizen science and the United Nations Sustainable Development Goals (vol 2, pg 922, 2019)

NATURE SUSTAINABILITY 2019年第11期2卷 1063-1063页

作者： Fritz, Steffen See, Linda Carlson, Tyler Haklay, Mordechai (Muki) Oliver, Jessie L. Fraisl, Dilek Mondardini, Rosy Brocklehurst, Martin Shanley, Lea A. Schade, Sven Wehn, Uta Abrate, Tommaso Anstee, Janet Arnold, Stephan Billot, Matthew Campbell, Jillian Espey, Jessica Gold, Margaret Hager, Gerid He, Shan Hepburn, Libby Hsu, Angel Long, Deborah Maso, Joan McCallum, Ian Muniafu, Maina Moorthy, Inian Obersteiner, Michael Parker, Alison J. Weisspflug, Maike West, Sarah Ecosystem Services and Management Program International Institute for Applied Systems Analysis Laxenburg Austria School of Resource and Environmental Management Simon Fraser University Burnaby Canada University College London London UK School of Electrical Engineering and Computer Science Queensland University of Technology Brisbane Australia Australian Citizen Science Association c/o Faculty of Science Partner Engagement and Outreach University of Sydney Sydney Australia University of Natural Resources and Life Sciences Vienna Austria Competence Center Citizen Science ETH Zurich and University of Zurich Zurich Switzerland Citizen Science Global Partnership Washington DC USA European Citizen Science Association Museum für Naturkunde Berlin Berlin Germany Nelson Institute University of Wisconsin at Madison Madison USA European Commission Joint Research Center Ispra Italy IHE Delft Institute for Water Education Delft The Netherlands World Meteorological Organization Geneva Switzerland Commonwealth Scientific and Industrial Research Organisation Canberra Australia Federal Statistical Office – Destatis Wiesbaden Germany UN Environment Programme Nairobi Kenya United Nations Sustainable Development Solutions Network New York USA CitizenScience.Asia Hong Kong China Yale-NUS College Singapore Singapore University of Dundee Dundee UK Scottish Environment LINK Perth UK Grumets Research Group CREAF Universitat Autònoma de Barcelona Barcelona Spain African Citizen Science Association Nairobi Kenya Woodrow Wilson Center Washington DC USA Museum für Naturkunde Berlin Berlin Germany Stockholm Environment Institute University of York York UK

Traditional data sources are not sufficient for measuring the United Nations Sustainable Development Goals. New and non-traditional sources of data are required. Citizen science is an emerging example of a non-traditional data source that is already making a contribution. In this Perspective, we present a roadmap that outlines how citizen science can be integrated into the formal Sustainable Development Goals reporting mechanisms. Success will require leadership from the United Nations, innovation from National Statistical Offices and focus from the citizen-science community to identify the indicators for which citizen science can make a real contribution.

关键词： Planning

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Combination of curcumin or chitosan with photodynamic therapy as an effective alternative therapy for overcoming wound infection associated with multidrug-resistant Acinetobacter baumannii

Microbe (Netherlands)

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Microbe (Netherlands) 2025年 7卷

作者： Yonpiam, Manta Wannigama, Dhammika Leshan Shein, Aye Mya Sithu Liao, Tingting Hurst, Cameron Monk, Peter N. Amarasiri, Mohan Phattharapornjaroen, Phatthranit Ounjai, Puey Saethang, Thammakorn Badavath, Vishnu Nayak Luk-in, Sirirat Nilgate, Sumanee Rirerm, Ubolrat Srisakul, Sukrit Ngamwongsatit, Natharin Leelahavanichkul, Asada Ragupathi, Naveen Kumar Devanga Kanjanabuch, Talerngsak Narkban, Phurin Miyanaga, Kazuhiko Cui, Longzhu Boontaveeyuwat, Einapak Higgins, Paul G. Kicic, Anthony Hamamoto, Hiroshi Abe, Shuichi Hongsing, Parichart Chatsuwan, Tanittha Department of Microbiology Faculty of Medicine Chulalongkorn University King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand Center of Excellence in Antimicrobial Resistance and Stewardship Research Faculty of Medicine Chulalongkorn University Bangkok Thailand Dual degree Medical Science program Faculty of Medicine Chulalongkorn University Bangkok 10330 Thailand Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan School of Medicine Faculty of Health and Medical Sciences The University of Western Australia Nedlands WA Australia Biofilms and Antimicrobial Resistance Consortium of ODA receiving countries The University of Sheffield Sheffield United Kingdom Pathogen Hunter's Research Team Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan Department of Infectious Diseases Faculty of Medicine Yamagata University Yamagata Japan Department of Clinical Epidemiology Faculty of Medicine Thammasat University Rangsit 10120 Thailand Department of Infection Immunity & Cardiovascular Disease University of Sheffield Medical School United Kingdom Department of Civil and Environmental Engineering Graduate School of Engineering Tohoku University Miyagi Japan Faculty of Health Science Technology Chulabhorn Royal Academy Bangkok 10210 Thailand HRH Princess Chulabhorn Disaster and Emergency Medicine Center Chulabhorn Royal Academy Bangkok 10210 Thailand Department of Biology Faculty of Science Mahidol University Bangkok Thailand Department of Computer Science Faculty of Science Kasetsart University Bangkok Thailand School of Pharmacy & Technology Management SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Hyderabad 509301 India Department of Clinical Microbiology and Applied Technology Faculty of Medical Technology Mahidol University Bangkok Thailand Department of Clinical Sciences and Public Health Faculty of Veteri

The increasing prevalence of multidrug-resistant Acinetobacter baumannii as an opportunistic pathogen in wound infections raises significant concerns due to its antibiotic resistance and biofilm-mediated antibiotic tolerance. This underscores the urgent need to explore an alternative approach to effectively managing wound infections caused by MDR A. baumannii. In this study, combining subinhibitory concentrations of curcumin (25 µg/ml) or chitosan (156 µg/ml) with photodynamic therapy-PDT (10 J/cm²) resulted in a significant reduction of planktonic viabilities and biofilm biovolume of MDR A. baumannii clinical isolates in vitro. In murine A. baumannii-associated wound infection, a combination of curcumin (25 µg/ml) or chitosan (156 µg/ml) with PDT (10 J/cm²) resulted in complete bacterial eradication with wound healing at Day 15 of post-treatments with these combination therapies. Our study demonstrated that combining curcumin or chitosan with PDT at their subinhibitory concentrations represents a promising alternative strategy as localized therapy for effectively managing A. baumannii-associated wound infection. © 2025 The Authors

关键词： Acinetobacter baumannii Alternative therapy Biofilm eradication Chitosan Curcumin Multidrug-resistant (MDR) Photodynamic therapy (PDT) Wound infection

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Outcomes from a Workshop on a National Center for Quantum Education

arXiv

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arXiv 2024年

作者： Barnes, Edwin Bennett, Michael B. Boltasseva, Alexandra Borish, Victoria Brown, Bennett Carr, Lincoln D. Ceballos, Russell R. Dukes, Faith Easton, Emily W. Economou, Sophia E. Edwards, E.E. Finkelstein, Noah D. Fracchiolla, C. Franklin, Diana Freericks, J.K. Goss, Valerie Hannum, Mark Holincheck, Nancy Kelly, Angela M. Lanes, Olivia Lewandowski, H.J. Matsler, Karen Jo Mercurio, Emily Montaño, Inès Murdock, Maajida Peltz, Kiera Perron, Justin K. Richardson, Christopher J.K. Rosenberg, Jessica L. Ross, Richard S. Ryu, Minjung Samuel, Raymond E. Schrode, Nicole Schwamberger, Susan Searles, Thomas A. Singh, Chandralekha Tingle, Alexandra Zwickl, Benjamin M. Department of Physics Virginia Tech Center for Quantum Information Science and Engineering Virginia Tech 850 West Campus Drive BlacksburgVA24061 United States Q-SEnSE NSF QLCI University of Colorado 440 UCB BoulderCO80301 United States Elmore Family School of Electrical and Computer Engineering Birck Nanotechnology Center Purdue Quantum Science and Engineering Institute Purdue University 610 Purdue Mall West LafayetteIN47907 United States Quantum Science Center A National Quantum Information Science Research Center of The U.S. Department of Energy Oak Ridge National Laboratory 1 Bethel Valley Road Oak RidgeTN37830 United States JILA National Institute of Standards and Technology the University of Colorado BoulderCO80309 United States Department of Physics University of Colorado 390 UCB BoulderCO80309 United States QuSTEAM 510 Ronalds St. Iowa CityIA52245 United States Quantum Engineering Program Department of Physics Colorado School of Mines 1523 Illinois St. GoldenCO80401 United States QuSTEAM Non-Profit Wilbur Wright College City Colleges of Chicago 4300 N Narragansett Ave ChicagoIL60634 United States Government and Community Relations Office - K-12 Programs Lawrence Berkeley National Laboratory 1 Cyclotron Road BerkeleyCA United States Chicago Quantum Exchange 5235 S. Harper Court ChicagoIL60615 United States Department of Physics Virginia Tech 850 West Campus Drive BlacksburgVA24060 United States Department of Electrical and Computer Engineering Duke Quantum Center Duke University Duke University 130 Hudson Hall DurhamNC27708 United States American Physical Society 555 12th St. NW WashingtonDC20004 United States Computer Science University of Chicago 5730 S. Ellis Ave. ChicagoIL60637 United States Department of Physics Georgetown University 552 Reiss Science Building WashingtonDC20057 United States Chemistry Physics and Engineering Studies Chicago State University 9501 S. King Drive WSC 309 ChicagoIL606

In response to numerous programs seeking to advance quantum education and workforce development in the United States, experts from academia, industry, government, and professional societies convened for a National science Foundation-sponsored workshop in February 2024 to explore the benefits and challenges of establishing a national center for quantum education. Broadly, such a center would foster collaboration and build the infrastructure required to develop a diverse and quantum-ready workforce. The workshop discussions centered around how a center could uniquely address gaps in public, K-12, and undergraduate quantum information science and engineering (QISE) education. Specifically, the community identified activities that, through a center, could lead to an increase in student awareness of quantum careers, boost the number of educators trained in quantum-related subjects, strengthen pathways into quantum careers, enhance the understanding of the U.S. quantum workforce, and elevate public engagement with QISE. Core proposed activities for the center include professional development for educators, coordinated curriculum development and curation, expanded access to educational laboratory equipment, robust evaluation and assessment practices, network building, and enhanced public engagement with quantum science. © 2024, CC BY.

关键词： Students

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Terahertz chiral photonic-crystal cavities for Dirac gap engineering in graphene

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Nature communications 2025年第1期16卷 5270页

作者： Fuyang Tay Stephen Sanders Andrey Baydin Zhigang Song Davis M Welakuh Alessandro Alabastri Vasil Rokaj Ceren B Dag Junichiro Kono Department of Electrical and Computer Engineering Rice University Houston TX USA. fuyang.tay@columbia.edu. Applied Physics Graduate Program Smalley-Curl Institute Rice University Houston TX USA. fuyang.tay@columbia.edu. Department of Electrical and Computer Engineering Rice University Houston TX USA. Smalley-Curl Institute Rice University Houston TX USA. Rice Advanced Materials Institute Rice University Houston TX USA. John A. Paulson School of Engineering and Applied Sciences Harvard University Cambridge MA USA. Max Planck Institute for the Structure and Dynamics of Matter Hamburg Germany. Department of Physics Harvard University Cambridge MA USA. ITAMP Harvard-Smithsonian Center for Astrophysics Cambridge MA USA. Department of Physics Villanova University Villanova PA USA. Department of Physics Indiana University Bloomington IN USA. Department of Electrical and Computer Engineering Rice University Houston TX USA. kono@rice.edu. Smalley-Curl Institute Rice University Houston TX USA. kono@rice.edu. Rice Advanced Materials Institute Rice University Houston TX USA. kono@rice.edu. Department of Physics and Astronomy Rice University Houston TX USA. kono@rice.edu. Department of Materials Science and NanoEngineering Rice University Houston TX USA. kono@rice.edu.

Strong coupling between matter and vacuum electromagnetic fields in a cavity can induce novel quantum phases in thermal equilibrium via symmetry breaking. Particularly intriguing is the coupling with circularly polarized cavity fields, which can break time-reversal symmetry (TRS) and lead to topological bands. This has spurred significant interest in developing chiral cavities that feature broken TRS, especially in the terahertz (THz) frequency range, where various large-oscillator-strength resonances exist. Here, we present a design for high-quality-factor THz chiral photonic-crystal cavities (PCCs) that achieve broken TRS using a magnetoplasma in a lightly doped semiconductor. We incorporate ab initio density functional theory calculations into the derived microscopic model, allowing a realistic estimate of the vacuum-induced gap in graphene when coupled to our chiral cavity. Our calculations show an enhancement in the light-matter interaction due to Dirac nodes and predict an energy gap on the order of 1 meV. The THz chiral PCCs offer a promising platform for exploring cavity-dressed condensed matter with broken TRS.

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Interplay of Purcell effect, stimulated emission, and leaky modes in photoluminescence spectra of microsphere cavities

arXiv

引用

arXiv 2019年

作者： Chien, Ching-Hang Wu, Shang-Hsuan Ngo, Trong Huynh-Buu Chang, Yia-Chung Research Center for Applied Sciences Academia Sinica Taipei115 Taiwan Nano Science and Technology Program TIGP Academia Sinica Taipei115 Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu300 Taiwan Department of Electrical and Computer Engineering University of Texas at Austin United States Department of Electrical and Computer Engineering University of Alberta EdmontonABT6G 2V4 Canada

A theoretical model for describing the emission spectra of microsphere cavities is presented, and its predictions of detailed lineshapes of emission spectra associated with whispering gallery modes (WGMs) of various orders in ZnO microspheres (MSs) are verified experimentally by photoluminescence (PL) spectroscopy. The interplay of Purcell effect, quality factor, and leaky modes in spontaneous and stimulated emission spectra related to WGMs of all orders is revealed. The key success of the theory is based on the expansion of the full Green function of the MS in terms of all possible resonance modes in complex frequency space, which allows incorporation of contributions from leaky modes, stimulated emission processes, and Purcell effect. We show that the spontaneous emission spectrum calculated according to Mie theory (without Purcell effect) is dominated by the contribution of leaky modes, while the spontaneous and stimulated emission enhanced by Purcell effect are responsible for the main WGM resonance peaks observed experimentally. It is found that the stimulated emission peaks are doubly enhanced by their respective mode quality factor Q: one factor from the Purcell effect and the other factor from the photon number derived from the rate equation. After combining all these effects the theory can provide a quantitative description of fine features of both TE and TM modes (including higher-order modes) observed in the PL spectra of ZnO MSs. Surprisingly, it is found that for ZnO MS with diameter larger than 5 µm, the PL emission spectrum is dominated by higher-order modes. The quantitative understanding of the interplay of these emission mechanisms should prove useful for optimizing the performance of light-emitting devices based on micro resonators. Copyright © 2019, The Authors. All rights reserved.

关键词： Microspheres

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ThermalProGAN: A sequence-based thermally stable protein generator trained using unpaired data

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Journal of bioinformatics and computational biology 2023年第1期21卷 2350008页

作者： Hui-Ling Huang Chong-Heng Weng Torbjörn E M Nordling Yi-Fan Liou International Program of Health Informatics and Management College of Management Chang Gung University No. 259 Wenhua 1st Road Guishan District Taoyuan City 33302 Taiwan. Department of Computer Science and Information Engineering National Central University No. 300 Zhongda Road Zhongli District Taoyuan City 320317 Taiwan. Department of Mechanical Engineering National Cheng Kung University No. 1 University Road Tainan City 701 Taiwan. Department of Applied Physics and Electronics Umeå University 90187 Umeå Sweden. Department of Virtual-Reality Interaction with Artificial Intelligence Technology Coretronic Reality Incorporation No. 5 Wenhua Rd. Hukou Township Hsinchu County 303 Taiwan.

MOTIVATION:The synthesis of proteins with novel desired properties is challenging but sought after by the industry and academia. The dominating approach is based on trial-and-error inducing point mutations, assisted by structural information or predictive models built with paired data that are difficult to collect. This study proposes a sequence-based unpaired-sample of novel protein inventor (SUNI) to build ThermalProGAN for generating thermally stable proteins based on sequence information. RESULTS:The ThermalProGAN can strongly mutate the input sequence with a median number of 32 residues. A known normal protein, 1RG0, was used to generate a thermally stable form by mutating 51 residues. After superimposing the two structures, high similarity is shown, indicating that the basic function would be conserved. Eighty four molecular dynamics simulation results of 1RG0 and the COVID-19 vaccine candidates with a total simulation time of 840[Formula: see text]ns indicate that the thermal stability increased. CONCLUSION:This proof of concept demonstrated that transfer of a desired protein property from one set of proteins is feasible. The source code of ThermalProGAN can be freely accessed at https://***/markliou/ThermalProGAN/ with an MIT license. The website is https://***:433. Supplementary data are available on Github.

关键词： CycleGAN Protein synthesis generative adversarial neural network thermal stability

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Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape

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Nature immunology 2024年第6期25卷 1123页

作者： Noah Gamble Alexandra Bradu Jason A Caldwell Joshua McKeever Olubusayo Bolonduro Ebru Ermis Caroline Kaiser YeEun Kim Benjamin Parks Sandy Klemm William J Greenleaf Gerald R Crabtree Andrew S Koh Department of Pathology University of Chicago Chicago IL USA. Graduate Program in Biophysical Sciences University of Chicago Chicago IL USA. Committee on Molecular Metabolism and Nutrition University of Chicago Chicago IL USA. Committee on Genetics Genomics Systems Biology University of Chicago Chicago IL USA. Department of Human Genetics University of Chicago Chicago IL USA. Immunology Program Stanford University Stanford CA USA. Department of Genetics Stanford University Stanford CA USA. Department of Computer Science Stanford University Stanford CA USA. Department of Applied Physics Stanford University Stanford CA USA. Chan Zuckerberg Biohub San Francisco CA USA. Department of Pathology Stanford University Stanford CA USA. Department of Developmental Biology Stanford University Stanford CA USA. Department of Pathology University of Chicago Chicago IL USA. akoh@uchicago.edu. Institute for Biophysical Dynamics University of Chicago Chicago IL USA. akoh@uchicago.edu.

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Erratum “15.9% organic tandem solar cell with extended near-infrared absorption” [Appl. Phys. Lett. 116, 153501 (2020)]

引用

applied Physics Letters 2021年第21期118卷

作者： Xinjing Huang Bangjin Sun Yongxi Li Chao Jiang Dejiu Fan Jian Fan Stephen R. Forrest 1Applied Physics Program University of Michigan Ann Arbor Michigan 48109 USA 2Institute of Functional Nano and Soft Materials Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Soochow University Suzhou Jiangsu 215123 China 3Department of Electrical Engineering and Computer Science University of Michigan Ann Arbor Michigan 48109 USA 4Department of Physics and Material Science and Engineering University of Michigan Ann Arbor Michigan 48109 USA

The authors regret that a related article was not cited in the original published article.1 In the first paragraph, the sentence “We introduce a surface treatme

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Lattice dynamics localization in low-angle twisted bilayer graphene

arXiv

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arXiv 2020年

作者： Gadelha, Andreij C. Ohlberg, Douglas A.A. Rabelo, Cassiano Neto, Eliel G.S. Vasconcelos, Thiago L. Campos, João L. Lemos, Jessica S. Ornelas, Vinícius Miranda, Daniel Nadas, Rafael Santana, Fabiano C. Watanabe, Kenji Taniguchi, Takashi van Troeye, Benoit Lamparski, Michael Meunier, Vincent Nguyen, Viet-Hung Paszko, Dawid Charlier, Jean-Christophe Campos, Leonardo C. Cançado, Luiz G. Medeiros-Ribeiro, Gilberto Jorio, Ado Physics Department Electrical Engineering Graduate Program Computer Science Department Universidade Federal de Minas Gerais Belo HorizonteMG31270-901 Brazil Physics Institute Universidade Federal da Bahia Campus Universitário de Ondina Salvador - BA40170-115 Brazil Divisão de Metrologia de Materiais Inmetro Duque de Caxias RJ25250-020 Brazil 1-2-1 Sengen Tsukuba-cityIbaraki305-0047 Japan Physics Applied Physics and Astronomy Jonsson Rowland Science Center Room 1C25 110 8th Street TroyNY12180 United States Louvain-la-Neuve Belgium

A low twist angle between the two stacked crystal networks in bilayer graphene enables self-organized lattice reconstruction with the formation of a periodic domain. This superlattice modulates the vibrational and electronic structures, imposing new rules for electron-phonon coupling and the eventual observation of strong correlation and superconductivity. Direct optical images of the crystal superlattice in reconstructed twisted bilayer graphene are reported here, generated by the inelastic scattering of light in a nano-Raman spectroscope. The observation of the crystallographic structure with visible light is made possible due to lattice dynamics localization, the images resembling spectral variations caused by the presence of strain solitons and topological points. The results are rationalized by a nearly-free-phonon model and electronic calculations that highlight the relevance of solitons and topological points, particularly pronounced for structures with small twist angles. We anticipate our discovery to play a role in understanding Jahn-Teller effects and electronic Cooper pairing, among many other important phonon-related effects, and it may be useful for characterizing devices in the most prominent platform for the field of *** Codes 82D03 Copyright © 2020, The Authors. All rights reserved.

关键词： Electronic structure

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Correction: Polygenic risk for triglyceride levels in the presence of a high impact rare variant

引用

BMC medical genomics 2023年第1期16卷 302页

作者： Shengjie Ying Tracy Heung Bhooma Thiruvahindrapuram Worrawat Engchuan Yue Yin Christina Blagojevic Zhaolei Zhang Robert A Hegele Ryan K C Yuen Anne S Bassett Institute of Medical Science University of Toronto Toronto ON Canada. Schulich School of Medicine and Dentistry Western University London ON Canada. Clinical Genetics Research Program Centre for Addiction and Mental Health Toronto ON Canada. The Dalglish Family 22Q Clinic University Health Network Toronto ON Canada. The Centre for Applied Genomics The Hospital for Sick Children Toronto ON Canada. Department of Molecular Genetics University of Toronto Toronto ON Canada. Donnelly Centre for Cellular and Biomolecular Research University of Toronto Toronto ON Canada. Department of Computer Science University of Toronto Toronto ON Canada. Institute of Medical Science University of Toronto Toronto ON Canada. anne.bassett@utoronto.ca. Clinical Genetics Research Program Centre for Addiction and Mental Health Toronto ON Canada. anne.bassett@utoronto.ca. The Dalglish Family 22Q Clinic University Health Network Toronto ON Canada. anne.bassett@utoronto.ca. Department of Psychiatry University of Toronto Toronto ON Canada. anne.bassett@utoronto.ca. Toronto General Hospital Research Institute and Campbell Family Mental Health Research Institute Toronto ON Canada. anne.bassett@utoronto.ca.

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