In this paper, we consider a joint scheduling algorithm which is a combination of Knopp and Humblet (KH) scheduling, which fully exploits multiuser diversity, and round-robin (RR) scheduling, which does not use multiu...
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Thin Si films on SiO2 that are completely melted by pulsed laser irradiation cool rapidly and eventually solidify via nucleation and growth of solids. It has been observed that a variety of solidified microstructures ...
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Molecular profiling strategies generally apply either transcriptomic or proteomic technologies for dissection of aberrant expression patterns between normal and diseased samples. Although studies in yeast ( S. cerevis...
Molecular profiling strategies generally apply either transcriptomic or proteomic technologies for dissection of aberrant expression patterns between normal and diseased samples. Although studies in yeast ( S. cerevisiae ) demonstrate excellent concordance between gene/protein abundance, the lack of integrated comparisons using human systems prompted us to stringently dissect these relationships in a cellular model system (platelets) devoid of active transcriptional activity. Highly-purified platelets from four healthy donors were pooled for proteomic analyses which were completed in duplicate using tryptic digestion of 100 mg cytoplasmic fractions, followed by cation exchange liquid chromatography coupled to tandem mass spectrometry (μLC-MS/MS). Spectral (peptide) counts were used as a semi-quantitative means of establishing protein abundance among normalized MS data sets, with excellent concordance between platelet runs (Spearman rank correlation r = 0.87, p <0.0001). Microarray data derived from five platelet apheresis donors were hybridized to the Affymetrix HU133a gene chip, and relative transcript abundance established by rank-ordering the unique, normalized set of non-redundant mRNAs (N=1240). Two comprehensive bioinformatics approaches using either platelet-restricted or genome-wide relational databases were additive in identifying 690 unique platelet proteins, representing increase of 230% or 131% to either approach alone. Of the identified proteins, 72% had a corresponding mRNA transcript, although a smaller fraction of mRNAs (41%) had a corresponding protein. The calculated codon adaptation index (CAI) for the 156 highest- and the 156 lowest-expressed platelet transcripts predicted strong correlation to protein abundance. Spearman correlations on data rank-ordered by either protein or transcript abundance demonstrated a maximal correlation coefficient of 0.44 (p =0.034) for an 18-member protein subset (higher protein abundance), although the 20 most abund
This paper presents a novel framework for simultaneously learning representation and control in continuous Markov decision processes. Our approach builds on the framework of proto-value functions, in which the underly...
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For the iterative solution of saddle point problems, a nonsymmetric preconditioner is studied which, with respect to the upper-left block of the system matrix, can be seen as a variant of SSOR. An idealized situation ...
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We survey conditions for rapid mixing of certain Markov chains, called Gibbs samplers, and uniqueness of certain probability measures with prescribed finite dimensional conditional distributions, called Gibbs measures...
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ISBN:
(纸本)9781604237924
We survey conditions for rapid mixing of certain Markov chains, called Gibbs samplers, and uniqueness of certain probability measures with prescribed finite dimensional conditional distributions, called Gibbs measures. By Tatikonda and Jordan's [1] sufficiency result, these criteria translate into conditions for convergence of the Sum-Product algorithm. The basic idea, which goes back to Dobrushin [2], is to show that the transition kernels (in the Gibbs sampler case) or the prescribed conditional distributions (in the Gibbs measure case) act as contractions on spaces of functions or measures, provided they are weakly influenced by neighboring sites. The contributions of this paper are as follows: We compare various notions of influence, unifying notation and terminology currently scattered across a large body of literature. We survey, generalize and extend existing proof techniques which fall in three broad categories: analytic arguments, coupling arguments, and arguments using path coupling. In particular, we extend all arguments from single sites to finite blocks and from total variation to Wasserstein distance;we introduce new matrix methods;we answer an open question by Weitz [3];and we provide evidence to support the superiority of path coupling, addressing a question raised by Sokal [4] regarding the dual relationship of analytic and coupling techniques.
The second-order Sigma-Delta (ΣΔ) scheme with linear quantization rule is analyzed for quantizing finite unit-norm tight frame expansions for Rd. Approximation error estimates are derived, and it is shown that for c...
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A three-dimensional wave packet generated by a local disturbance in a two-dimensional hypersonic boundary layer flow is studied with the aid of the previously solved initialvalue problem. The solution can be presented...
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ISBN:
(纸本)1563478102
A three-dimensional wave packet generated by a local disturbance in a two-dimensional hypersonic boundary layer flow is studied with the aid of the previously solved initialvalue problem. The solution can be presented as a sum of modes consisting of continuous and discrete spectra of temporal stability theory. Two discrete modes, known as Mode S and Mode F, are of interest in high-speed flows since they may be involved in a laminar-turbulent transition scenario. The continuous and discrete spectra are analyzed numerically for a hypersonic flow. A comprehensive study of the spectrum is performed, including Reynolds number, Mach number and temperature factor effects. A specific disturbance consisting of an initial temperature spot is considered, and the receptivity to this initial temperature spot is computed for both the two-dimensional and three-dimensional cases. Using the analysis of the discrete and continuous spectrum, the inverse Fourier transform is computed numerically. The two-dimensional inverse Fourier transform is calculated for Mode F and Mode S. The Mode S result is compared with an asymptotic approximation of the Fourier integral, which is obtained using a Gaussian model as well as the method of steepest descent. Additionally, the three-dimensional inverse Fourier transform is found using an asymptotic approximation. Using the inverse Fourier transform computations, the development of the wave packet is studied, including effects due to Reynolds number, Mach number and temperature factor.
In this paper we apply a multiobjective optimization model of Smart Growth to land development. The term Smart Growth is meant to describe development strategies-that do not promote urban sprawl. However, the term is ...
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