Cancellous bone plays an important load-bearing role in the skeleton, yet relatively little is known about the microstructure-mechanical property relationships of the tissue at the sub-10 [.proportional]m level. Cance...
Cancellous bone plays an important load-bearing role in the skeleton, yet relatively little is known about the microstructure-mechanical property relationships of the tissue at the sub-10 [.proportional]m level. Cancellous tissue is characterized by a layered microstructure with variable proportions of collagen and mineral. The lamellar material is substantially stiffer than the interlamellar material at the nanomechanical level. However, the microstructural origin of the observed differences in mechanical properties of these structures has not been investigated. In this study, second harmonic generation microscopy was used to examine collagen in human vertebral cancellous bone. At the same location in the tissue, nanoindentation was used to assess the indentation modulus of lamellar and interlamellar bone. The stiff lamellae corresponded to areas of highly ordered, collagen-rich material, while the compliant interlamellar regions corresponded to areas of unoriented or collagen-poor material. The lamellar bone was approximately 30% stiffer and contained approximately 50% more oriented collagen than the interlamellar bone. These observed differences in the mechanical properties and collagen content and organization of lamellar and interlamellar tissue are consistent with previous scanning electron microscopy studies showing greater mineral and collagen content and organization in lamellar bone. Given the well-known coupling between collagen and mineral in bone tissue, the mineral distribution may mirror that of the aligned collagen. However, similar measurements of local variations in mineral content are needed to confirm this hypothesis and may provide additional insights into the tissue nanomechanical behavior.
In contrast to intensity-based fluorescence microscopy, fluorescence lifetime imaging microscopy (FLIM) bases image contrast on fluorophore excited-state lifetime. This technique is sensitive to the fluorophore's ...
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Drs. Santamouris, Tsagkrasoulis and Littlefair comment on Laouadi's work which is a part of a completed project to develop a user-friendly computer tool (SkyVision) to predict the optical and daylighting performan...
Drs. Santamouris, Tsagkrasoulis and Littlefair comment on Laouadi's work which is a part of a completed project to develop a user-friendly computer tool (SkyVision) to predict the optical and daylighting performance of projecting skylights. Drs. Santamouris and Tsagkrasoulis suggest the importance of comparing results from daylighting software with those from the presented methodology. Responding to this, Laouadi states that the task is simple if the skylight is treated as one component with equivalent optical properties, which are calculated by a specialized tool. Dr. Littefair claims that the skylight shape is not usually taken into account in daylighting calculations. For his part, Louadi provides evidence that the skylight shape is an important parameter in skylight design in that it may boost or reduce the amount of light and solar heat getting into the indoor space.
This paper presents the novel insight that the SLAM information matrix is exactly sparse in a delayed-state framework. Such a framework is used in view-based representations of the environment which rely upon scan-mat...
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This paper presents the novel insight that the SLAM information matrix is exactly sparse in a delayed-state framework. Such a framework is used in view-based representations of the environment which rely upon scan-matching raw sensor data. Scan-matching raw data results in virtual observations of robot motion with respect to a place its previously been. The exact sparseness of the delayed-state information matrix is in contrast to other recent feature based SLAM information algorithms like Sparse Extended Information Filters or Thin Junction Tree Filters. These methods have to make approximations in order to force the feature-based SLAM information matrix to be sparse. The benefit of the exact sparseness of the delayed-state framework is that it allows one to take advantage of the information space parameterization without having to make any approximations. Therefore, it can produce equivalent results to the “full-covariance” solution.
Femtosecond laser ablation of Silicon (100) with thermal oxide thin films was studied in order to further understand the ablative properties of thin films and to evaluate their influence on the ablation of the substra...
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Femtosecond pulsed laser damage of Silicon (100) with thermal oxide thin films was studied in order to further understand the optical and electrical properties of thin films and to evaluate their influence on the dama...
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A highly unusual pattern of strong multiple resonances for bulk electromagnetic waves is predicted and analysed numerically in thick periodic holographic gratings in a slab with the mean permittivity that is larger th...
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A highly unusual pattern of strong multiple resonances for bulk electromagnetic waves is predicted and analysed numerically in thick periodic holographic gratings in a slab with the mean permittivity that is larger than that of the surrounding media. This pattern is shown to exist in the geometry of grazing-angle scattering (GAS), that is when the scattered wave (+1 diffracted order) in the slab propagates almost parallel to the slab (grating) boundaries. The predicted resonances are demonstrated to be unrelated to resonant generation of the conventional guided modes of the slab. Their physical explanation is associated with resonant generation of a completely new type of eigenmodes in a thick slab with a periodic grating. These new slab eigenmodes are generically related to the grating; they do not exist if the grating amplitude is zero. The field structure of these eigenmodes and their dependence on structural and wave parameters is analysed. The results are extended to the case of GAS of guided modes in a slab with a periodic groove array of small corrugation amplitude and small variations in the mean thickness of the slab at the array boundaries.
Highly selective and repeatable delamination of thermal oxide films from Si(100) substrates has been performed using single and multiple femtosecond laser pulses forming bubbles or blisters. By overlapping the bubbles...
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The chemical mechanisms underlying the growth of cave formations such as stalactites are well known, yet no theory has yet been proposed which successfully accounts for the dynamic evolution of their shapes. Here we c...
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The chemical mechanisms underlying the growth of cave formations such as stalactites are well known, yet no theory has yet been proposed which successfully accounts for the dynamic evolution of their shapes. Here we consider the interplay of thin-film fluid dynamics, calcium carbonate chemistry, and CO2 transport in the cave to show that stalactites evolve according to a novel local geometric growth law which exhibits extreme amplification at the tip as a consequence of the locally-varying fluid layer thickness. Studies of this model show that a broad class of initial conditions is attracted to an ideal shape which is strikingly close to a statistical average of natural stalactites.
Recent simulations indicate that ellipsoids can pack randomly more densely than spheres and, remarkably, for axes ratios near 1.25∶1∶0.8 can approach the densest crystal packing (fcc) of spheres, with a packing frac...
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Recent simulations indicate that ellipsoids can pack randomly more densely than spheres and, remarkably, for axes ratios near 1.25∶1∶0.8 can approach the densest crystal packing (fcc) of spheres, with a packing fraction of 74%. We demonstrate that such dense packings are realizable. We introduce a novel way of determining packing density for a finite sample that minimizes surface effects. We have fabricated ellipsoids and show that, in a sphere, the radial packing fraction ϕ(r) can be obtained from V(h), the volume of added fluid to fill the sphere to height h. We also obtain ϕ(r) from a magnetic resonance imaging scan. The measurements of the overall density ϕavr, ϕ(r) and the core density ϕ0=0.74±0.005 agree with simulations.
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