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Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021

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The Lancet Public Health 2025年第3期10卷 e172-e188页

作者： Steel, Nicholas Bauer-Staeb, Clarissa Maria Mercedes Ford, John A. Abbafati, Cristiana Abdalla, Mohammed Altigani Abdelkader, Atef Abdi, Parsa Zuñiga, Roberto Ariel Abeldaño Abiodun, Olugbenga Olusola Abolhassani, Hassan Abu-Gharbieh, Eman Abukhadijah, Hana J. Abu-Zaid, Ahmed Addo, Isaac Yeboah Addolorato, Giovanni Adekanmbi, Victor Adetunji, Juliana Bunmi Adeyeoluwa, Temitayo Esther Agardh, Emilie E. Agyemang-Duah, Williams Ahmad, Danish Ahmed, Ayman Ahmed, Syed Anees Akinosoglou, Karolina Akkaif, Mohammed Ahmed Al Awaidy, Salah Al Hasan, Syed Mahfuz Al Zaabi, Omar Ali Mohammed Aldridge, Robert W. Algammal, Abdelazeem M. Al-Gheethi, Adel Ali Saeed Ali, Abid Ali, Mohammed Usman Ali, Syed Shujait Ali, Waad Alicandro, Gianfranco Alif, Sheikh Mohammad Al-Jumaily, Adel Allebeck, Peter Alrawashdeh, Ahmad Al-Rifai, Rami H. Alsabri, Mohammed A. Alshahrani, Najim Z. Aluh, Deborah Oyine Al-Wardat, Mohammad Al-Zyoud, Walid A. Amiri, Sohrab Anderlini, Deanna Andrei, Catalina Liliana Anil, Abhishek Anvari, Saeid Anyasodor, Anayochukwu Edward Appiah, Seth Christopher Yaw Aquilano, Michele Arabloo, Jalal Arafat, Mosab Areda, Demelash Aremu, Abdulfatai Armani, Keivan Armocida, Benedetta Ärnlöv, Johan Asaduzzaman, Muhammad Astell-Burt, Thomas Aujayeb, Avinash Ausloos, Marcel Azadnajafabad, Sina Aziz, Shahkaar Azzam, Ahmed Y. Babu, Giridhara Rathnaiah Badache, Andreea Corina Badiye, Ashish D. Bahramian, Saeed Baig, Atif Amin Baker, Jennifer L. Bansal, Hansi Bärnighausen, Till Winfried Barone, Mark Thomaz Ugliara Barrow, Amadou Barteit, Sandra Bashir, Shahid Bashiru, Hameed Akande Basso, João Diogo Bastan, Mohammad-Mahdi Basu, Sanjay Batra, Kavita Bauckneht, Matteo Baune, Bernhard T. Beghi, Massimiliano Beiranvand, Maryam Béjot, Yannick Bell, Michelle L. Bello, Olorunjuwon Omolaja Belo, Luis Beloukas, Apostolos Beneke, Alice A. Bettencourt, Paulo J.G. Bhagavathula, Akshaya Srikanth Bhala, Neeraj Bhaskar, Sonu Bisulli, Francesca Bjørge, Tone Bodunrin, Aadam Olalekan Carvajal, Alejandro Botero Bouaoud, Souad Brayne, Carol Brenner, H Department of Primary Care and Public Health University of East Anglia Norwich United Kingdom Office for Health Improvement and Disparities Department of Health and Social Care London United Kingdom Department of Legal and Economic Studies La Sapienza University Rome Italy Rome Italy Hull York Medical School University of Hull Hull United Kingdom Department of Mathematics and Sciences Ajman University Ajman United Arab Emirates Department of Medicine Memorial University St. John's NL Canada Postgraduate Department University of Sierra Sur Miahuatlan de Porfirio Diaz Mexico Yhteiskuntadatatieteen keskus (Centre for Social Data Science) Helsinki Finland Department of Internal Medicine Federal Medical Centre Abuja Nigeria Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Department of Medical Biochemistry and Biophysics Karolinska Institutet (Karolinska Institute) Stockholm Sweden Department of Clinical Sciences University of Sharjah Sharjah United Arab Emirates Department of Biopharmaceutics and Clinical Pharmacy University of Jordan Amman Jordan Medical Research Center Hamad Medical Corporation Doha Qatar Department of Biochemistry and Molecular Medicine Alfaisal University Riyadh Saudi Arabia College of Graduate Health Sciences University of Tennessee Memphis TN United States School of Medicine Sydney NSW Australia Centre for Social Research in Health University of New South Wales Sydney NSW Australia Internal Medicine and Alcohol Related Disease Unit Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy Department of Medical and Surgical Sciences Università Cattolica di Roma (Catholic University of Rome) Rome Italy Department of Obstetrics and Gynecology University of Texas Medical Branch Galveston TX United States Department of Biochemistry Osun State University Osogbo Nigeria Department of Pharmacology and Therapeutics University of Medical Sciences Ondo Ondo Nigeria Department of Veteri

Background: Decades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and cause-specific death rates in different European countries related to changes in life expectancy in those countries before and during the COVID-19 pandemic. Methods: We used data and methods from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to compare changes in life expectancy at birth, causes of death, and population exposure to risk factors in 16 European Economic Area countries (Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, and Sweden) and the four UK nations (England, Northern Ireland, Scotland, and Wales) for three time periods: 1990–2011, 2011–19, and 2019–21. Changes in life expectancy and causes of death were estimated with an established life expectancy cause-specific decomposition method, and compared with summary exposure values of risk factors for the major causes of death influencing life expectancy. Findings: All countries showed mean annual improvements in life expectancy in both 1990–2011 (overall mean 0·23 years [95% uncertainty interval [UI] 0·23 to 0·24]) and 2011–19 (overall mean 0·15 years [0·13 to 0·16]). The rate of improvement was lower in 2011–19 than in 1990–2011 in all countries except for Norway, where the mean annual increase in life expectancy rose from 0·21 years (95% UI 0·20 to 0·22) in 1990–2011 to 0·23 years (0·21 to 0·26) in 2011–19 (difference of 0·03 years). In other countries, the difference in mean annual improvement between these periods ranged from –0·01 years in Iceland (0·19 years [95% UI 0·16 to 0·21] vs 0·18 years [0·09 to 0·26]), to –0·18 years in England (0·25 years [0·24 to 0·25] vs 0·07 years [0·06 to 0·08]). In 2019–21, there was an overall decrease in mean annual life expectancy a

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Electronic Charge Transport: Breakdown of the Small‐Polaron Hopping Model in Higher‐Order Spinels (Adv. Mater. 49/2020)

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Advanced Materials 2020年第49期32卷 2070368-2070368页

作者： Anuj Bhargava Roni Eppstein Jiaxin Sun Michelle A. Smeaton Hanjong Paik Lena F. Kourkoutis Darrell G. Schlom Maytal Caspary Toroker Richard D. Robinson Department of Materials Science and Engineering Cornell University Ithaca NY 14853 USA Department of Materials Science and Engineering Technion—Israel Institute of Technology Haifa 3200003 Israel Platform for the Accelerated Realization Analysis and Discovery of Interface Materials (PARADIM) Cornell University Ithaca NY 14853 USA School of Applied and Engineering Physics Cornell University Ithaca NY 14853 USA Kavli Institute at Cornell for Nanoscale Science Ithaca NY 14853 USA Leibniz‐Institut für Kristallzüchtung Berlin 12489 Germany The Nancy and Stephen Grand Technion Energy Program Technion—Israel Institute of Technology Haifa 3200003 Israel

For six decades, electronic charge transport in oxides has been described by the small‐polaron hopping model. However, this model was developed for binary oxides only. By characterizing structure, site occupation, and transport, in article number 2004490, Maytal Caspary Toroker, Richard D. Robinson, and co‐workers show that the conventional model is inaccurate for oxides with more than two types of cation. They present an accurate model, opening new design avenues for high‐performance devices.

关键词： cation site occupation electronic conductivity molecular‐beam epitaxy small‐polaron hopping spinels

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Visualization of acoustic streaming produced by lithotripsy field using a PIV method

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Journal of physics: Conference Series 2004年第1期1卷

作者： M J Choi D H Doh C H Cho K S Kang D G Paeng N H Ko K S Kim G H Rim A J Coleman Medical and Industrial Ultrasound Group NPL Teddington TW11 0LW UK Department of Medicine Cheju National University 690-756 Republic of Korea Interdisciplinary Postgraduate Program in Biomedical Eng. Cheju National University 690-756 Republic of Korea Mechanical & Information Eng Korea Maritime University Pusan Republic of Korea Applied Electrophysics Research Group KERI Chang-Wan Rep of Korea Department of Biomedical Eng Dong-Ah University Hospital Pusan Republic of Korea Medical Physics Department Guy's and St Thomas' Hospital London SE1 7EH UK

We visualized the acoustic streaming produced in water by an experimental lithotripter using a particle image velocimetry (PIV) method. Streaming generated around the beam focus has been optically visualized using light scattering particles and was easily noticeable even with naked eye for all electrical settings of the lithotripter. Spatial distributions of velocity vectors are complicated and several local peaks and vortices are observed. Measured streaming velocities are found to be in ranges of 1.5 - 3 cm/s. It should be noted that the measured velocity was averaged over 1/30 sec, the time resolution limited by video frame rate, and the true velocity is expected to be at least 10 times higher. Despite such an underestimation, it was shown that the streaming velocity increased with voltage settings and, as predicted by theory, is proportional to intensity and closely related to the shock-wave pressures generated. In particular, the velocity has almost a linear correlation with peak-negative pressures (r = 0.98683, p = 0.0018). This suggests that the streaming velocity measured using the PIV technique can be used to estimate the generated peak-pressures without disturbing the field.

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2374. Genomic Characteristics of RecurrentStaphylococcus aureusSkin and Soft-Tissue Infection Among US Army Trainees

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Open Forum Infectious Diseases 2018年第SUPPL_1期5卷 S707–S707页

作者： Verratti, Kathleen Player, Robert Wood, Shannon Schlett, Carey Elassal, Emad Forsyth, Ellen Ellis, Michael Tribble, David R Millar, Eugene Bennett, Jason Johns Hopkins Applied Physics Laboratory Laurel Maryland Infectious Diseases Walter Reed National Military Medical Center Bethesda Maryland Infectious Disease Clinical Research Program Department of Preventive Medicine and Biostatistics Uniformed Services University of the Health Sciences Bethesda Maryland Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. Bethesda Maryland International Reagent Resource American Type Tissue Collection Manassas Virginia University of Toledo College of Medicine and Life Sciences Toledo Ohio Walter Reed Army Institute of Research Silver Spring Maryland Department of Medicine Uniformed Services University of the Health Sciences Bethesda Maryland

Background Skin and soft-tissue infections (SSTI) are common among military recruits, and some experience recurrent SSTI (two infections ≥30 days apart) during training. We used whole-genome sequencing (WGS) to assess the relatedness of strains from recurrent S. aureus SSTI cases and their close contacts. Methods From 2010 to 2014, we prospectively identified SSTI cases among US Army Infantry trainees (Fort Benning, GA), obtaining infection swabs at the time of presentation for all SSTIs and multiple anatomic site colonization swabs at the time of presentation for the first infection. Thereafter, we selected cases of recurrent S. aureus SSTI with phenotypically concordant paired isolates (e.g., MRSA-MRSA). We also selected concordant colonization isolates from recurrent cases as well as concordant infection isolates from SSTI cases in the same training class as the recurrent case. Isolates were characterized by WGS. The number of single nucleotide polymorphism (SNP) differences between isolates was calculated. Phylogenetic trees were constructed to identify patterns of intra- vs. extra-host S. aureus acquisition among cases of recurrent infection. Results We identified 23 cases of recurrent S. aureus SSTI with concordant infection isolates (18 MRSA). The median (range) pairwise SNP difference for intrahost infection isolates was 15 (0–3,768); 12 (0–348), MRSA and 310 (3–3,768), MSSA. Nine (39%) were colonized with a concordant strain (5 MRSA), yielding 14 colonization isolates (7 MRSA). The median pairwise SNP difference between intrahost colonization and recurrent infection isolates was 57 (2–3,582); 5 (2–3,582), MRSA and 167 (2–313), MSSA. Infection isolates from 33 proximal cases (27 MRSA) were identified. The median pairwise SNP difference between recurrent infection isolates and that of a proximal case was 24 (1–531); 20 (1–216), MRSA and 307 (286–531), MSSA. Variant analysis showed no difference between the number of putative high impact SNPs between infection

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Author Correction: Highly efficient, heat dissipating, stretchable organic light-emitting diodes based on a MoO3/Au/MoO3 electrode with encapsulation

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Nature communications 2021年第1期12卷 7355页

作者： Dae Keun Choi Dong Hyun Kim Chang Min Lee Hassan Hafeez Subrata Sarker Jun Su Yang Hyung Ju Chae Geon-Woo Jeong Dong Hyun Choi Tae Wook Kim Seunghyup Yoo Jinouk Song Boo Soo Ma Taek-Soo Kim Chul Hoon Kim Hyun Jae Lee Jae Woo Lee Donghyun Kim Tae-Sung Bae Seung Min Yu Yong-Cheol Kang Juyun Park Kyoung-Ho Kim Muhammad Sujak Myungkwan Song Chang-Su Kim Seung Yoon Ryu Division of Display and Semiconductor Physics Display Convergence College of Science and Technology Korea University Sejong Campus Sejong City Republic of Korea. Department of Applied Physics Korea University Sejong Campus Sejong City Republic of Korea. E-ICT-Culture-Sports Convergence Track Korea University Sejong Campus Sejong City Republic of Korea. Division of Display and Semiconductor Physics Display Convergence College of Science and Technology Korea University Sejong Campus Sejong City Republic of Korea. hassaniskt@***. Department of Applied Physics Korea University Sejong Campus Sejong City Republic of Korea. hassaniskt@***. School of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon Republic of Korea. Department of Mechanical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon Republic of Korea. Department of Advanced Materials Chemistry College of Science and Technology Korea University Sejong Campus Sejong City Republic of Korea. Interdisciplinary Graduate Program for Artificial Intelligence Smart Convergence Technology Korea University Sejong Republic of Korea. Jeonju Center Korea Basic Science Institute (KBSI) Analysis & Researcher Division Jeollabuk-do Republic of Korea. Department of Chemistry Pukyong National University 45 Yongso-Ro Nam-gu Busan Republic of Korea. Department of Physics Chungbuk National University Cheongju Republic of Korea. Surface Materials Division Korea Institute of Materials Science (KIMS) Changwon Republic of Korea. Surface Materials Division Korea Institute of Materials Science (KIMS) Changwon Republic of Korea. cskim1025@kims.re.kr. Division of Display and Semiconductor Physics Display Convergence College of Science and Technology Korea University Sejong Campus Sejong City Republic of Korea. justie74@korea.ac.kr. Department of Applied Physics Korea University Sejong Campus Sejong City Republic of Korea. justie74@korea.ac.kr. E-ICT-Culture-Sports Conve

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Human neutralizing antibodies isolated from a Zika patient and their molecular determinants

Human neutralizing antibodies isolated from a Zika patient a...

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第十一届全国免疫学学术大会

作者： Wang Qihui Yang Huabing Liu Xiaoqing Dai Lianpan Ma Tong Qi Jianxun Wong Gary Peng Ruchao Liu Sheng Li Junfu Li Shihua Song Jian Liu Jianying He Jianhua Yuan Hui Xiong Ying Liao Yong Li Jianhua Yang Jianping Tong Zhou Griffin Bryan Bi Yuhai Liang Mifang Xu Xiaoning Qin Chuan Cheng Gong Wang Peiyi Qiu Xiangguo Kobinger Gary Shi Yi Yan Jinghua Gao Fu CAS Key Laboratory of Microbial Physiological and Metabolic Engineering Institute of Microbiology Chinese Academy of Sciences Shenzhen Key Laboratory of Pathogen and Immunity Shenzhen Third People’s Hospital School of Life Sciences Anhui University Jiangxi province center for disease control and prevention Research Network of Immunity and Health (RNIH) Beijing Institutes of Life Science Chinese Academy of Sciences CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of Microbiology Chinese Academy of Sciences CAS Center for Influenza Research and Early-warning (CASCIRE) Chinese Academy of Sciences School of Life Sciences University of Science and Technology of China Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases School of Medicine Tsinghua University Shanghai Institute of Applied Physics Chinese Academy of Sciences Ganzhou Prefecture Center for Disease Control and Prevention Special Pathogens Program National Microbiology Laboratory Public Health Agency of Canada National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention (China CDC) MRC Human Immunology Unit University of Oxford Key Laboratory of Human Diseases Comparative Medicine Ministry of Health Institute of Medical Laboratory Animal Science Chinese Academy of Medical Sciences Faculty of Biological Science University of Leeds College of Life Sciences University of Chinese Academy of Sciences Savaid Medical School University of Chinese Academy of Sciences

Zika virus infections are associated with fetal microcephaly,neurological complications and constitute a public health ***,we report the isolation of 13 specific,human-origin monoclonal antibodies from an imported Zika case to *** of the isolated antibodies(Z23 and Z3L1)demonstrate potent Zika-specific neutralization in vitro without binding or neutralizing activity against Zika’s closest relative Dengue virus(DENV)1-4,

关键词： Zika virus envelope protein human neutralizing MAbs B cell sequencing crystal structure Cryo-EM

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Navigating the challenges in creating complex data systems: a development philosophy

arXiv

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arXiv 2022年

作者： Dittmer, Sören Roberts, Michael Gilbey, Julian Biguri, Ander Preller, Jacobus Rudd, James H.F. Aston, John A.D. Schönlieb, Carola-Bibiane Selby, Ian Breger, Anna Thorpe, Matthew Weir-McCall, Jonathan R. Gkrania-Klotsas, Effrossyni Korhonen, Anna Jefferson, Emily Langs, Georg Yang, Guang Prosch, Helmut Stanczuk, Jan Tang, Jing Babar, Judith Sánchez, Lorena Escudero Teare, Philip Patel, Mishal Wassin, Marcel Holzer, Markus Walton, Nicholas Lió, Pietro Shadbahr, Tolou Sala, Evis Department of Applied Mathematics and Theoretical Physics University of Cambridge Cambridge United Kingdom Addenbrooke’s Hospital Cambridge University Hospitals NHS Trust Cambridge United Kingdom Department of Medicine University of Cambridge Cambridge United Kingdom Department of Pure Mathematics and Mathematical Statistics University of Cambridge Cambridge United Kingdom ZeTeM University of Bremen Bremen Germany Department of Radiology University of Cambridge Cambridge United Kingdom Faculty of Mathematics University of Vienna Austria Department of Mathematics University of Manchester Manchester United Kingdom Royal Papworth Hospital Cambridge Royal Papworth Hospital NHS Foundation Trust Cambridge United Kingdom Language Technology Laboratory University of Cambridge Cambridge United Kingdom Population Health and Genomics School of Medicine University of Dundee Dundee United Kingdom Department of Biomedical Imaging and Image-guided Therapy Computational Imaging Research Lab Medical University of Vienna Vienna Austria National Heart and Lung Institute Imperial College London London United Kingdom Research Program in Systems Oncology Faculty of Medicine University of Helsinki Helsinki Finland Data Science & Artificial Intelligence AstraZeneca Cambridge United Kingdom Clinical Pharmacology & Safety Sciences AstraZeneca Cambridge United Kingdom Contextflow GmbH Vienna Austria Institute of Astronomy University of Cambridge Cambridge United Kingdom Department of Computer Science and Technology University of Cambridge Cambridge United Kingdom

In this perspective, we argue that despite the democratization of powerful tools for data science and machine learning over the last decade, developing the code for a trustworthy and effective data science system (DSS) is getting harder. Perverse incentives and a lack of widespread software engineering (SE) skills are among many root causes we identify that naturally give rise to the current systemic crisis in reproducibility of DSSs. We analyze why SE and building large complex systems is, in general, hard. Based on these insights, we identify how SE addresses those difficulties and how we can apply and generalize SE methods to construct DSSs that are fit for purpose. We advocate two key development philosophies, namely that one should incrementally grow – not biphasically plan and build – DSSs, and one should always employ two types of feedback loops during development: one which tests the code’s correctness and another that evaluates the code’s efficacy. Copyright © 2022, The Authors. All rights reserved.

关键词： Software engineering

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ACQUISITION REFORM AND BEST PRODUCT PROCUREMENT - AN ENGINEERING VIEW

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NAVAL ENGINEERS JOURNAL 1994年第6期106卷 41-57页

作者： FISHER, DA SKOLNICK, A He has been involved with several weapon system developments. Among these were the Trident II fire control and navigation systems the BSY-I Anti-Submarine Warfare System and the Navy standard computers (UYK44 and EMSP). He served as manager of the Digital Circuits Engineering Branch and was then appointed as manager of the Automatic Test Equipment (ATE) Technology Division. As manager of the ATE Technology Division he was responsible for the SP-23 Fire Control System Support Project the SP-24 Navigation Project and the Fleet Progressive Maintenance Program (2M/ATE). This Division was responsible for selection and application of electronic product technology and for developing fleet test and repair techniques. He holds a B.S. in Electrical Engineering from the University of Evansville and is currently pursuing a Masters of Public Administration at Indiana University-Purdue University Indianapolis. Dr. Alfred Skolnick:retired from the Navy in 1983 with the rank of captain. He is president of System Science Consultants (SSC) specializing in strategic planning technical program definition technology assessment and engineering analyses on selected matters of national interest. Dr. Skolnick taught mathematics and management sciences at University of Virginia and Marymount University. He is adjunct faculty at Northern Virginia Community College. From 1985 to 1989 he was president of the American Society of Naval Engineers. In the Navy he served at Applied Physics Laboratory/The Johns Hopkins University then aboard USSBoston(CAG-1) and played leading roles in several weapon system developments inertial navigation (Polaris) deep submergence (DSRV) and advanced ship designs (SES). He later was director Combat System Integration Naval Sea Systems Command and head Combat Projects Naval Ship Engineering Center. In 1975 he became a major project manager and led the Navy's High Energy Lasers Program in 1981 he was assigned all Navy Directed Energy Weapons development efforts. He was vice president advanced tech

The military services are being moved in the direction of performance-based specifications and standards. They are being steered against dictating ''how to'' produce an item since such action forecloses on the ability to gain access to components or technology that may have a commercial equivalent. Why should the engineering community embrace the new approach? Aside from the obvious weight of it being approved policy, therefore currently mandated, it warrants examination because it is the correct approach at this time when applied to appropriate products. Military specifications and standards are to be displaced then, by acceptable alternative contractor design solutions. Industry bidders will be allowed to propose the particular design details, permitting procurement flexibility by contractually citing only system level or interface requirements, both physical and functional. Hopefully, this can broaden the industrial base and increase competition with reduced costs to follow. Conceptually, the approach appears both performance-sensible and cost-attractive (there are, of course, consequent risks) but how does implementation proceed? Is it possible to pursue the goals envisioned along paths that are not in themselves experimental? Can the American postulate, minimal loss of life and limb to U.S. military people, continue to be honored? Experience and track record elsewhere imply encouraging possibilities in select situations-useful prospects are identified and discussed in practical terms.

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Lung cancer cells detection by a photoelectrochemical MoS2 biosensing chip

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Biomedical Optics Express 2024年第2期15卷 753-771页

作者： Chun-Liang Lai Riya Karmakar Arvind Mukundan Wei-Chung Chen I-Chen Wu Vladimir E. Fedorov Shih-Wei Feng Ubol Choomjinda Shu-Fang Huang Hsiang-Chen Wang Division of Pulmonology and Critical Care Department of Internal Medicine Dalin Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation No. 2 Minsheng Road Dalin Chiayi 62247 Taiwan School of Medicine Tzu Chi University 701 Zhongyang Rd. Sec. 3 Hualien 97004 Taiwan Department of Mechanical Engineering and Center for Innovative Research on Aging Society (CIRAS) National Chung Cheng Universityhttps://***/0028v3876 168 University Road Min Hsiung Chiayi City 62102 Taiwan Ph.D. Program in Environmental and Occupational Medicine Kaohsiung Medical University Kaohsiung 807 Taiwan Department of Medicine and Graduate Institute of Clinical Medicine College of Medicine Kaohsiung Medical University No. 100 Tzyou 1st Rd. Sanmin Dist. Kaohsiung City 80756 Taiwan Nikolaev Institute of Inorganic Chemistry Siberian Branch of Russian Academy of Sciences Novosibirsk 630090 Russia Department of Natural Sciences Novosibirsk State University 1 Pirogova str. Novosibirsk 630090 Russia Department of Applied Physics National University of Kaohsiung 700 Kaohsiung University Rd. Nanzih District Kaohsiung 81148 Taiwan School of Nursing Shinawatra University 99 Moo 10 Bangtoey Samkhok Pathum Thani 12160 Thailand Division of Chest Medicine Kaohsiung Armed Forces General Hospital 2 Zhongzheng 1st. Rd. Kaohsiung City 80284 Taiwan ryanhuang1128@*** hcwang@ccu.edu.tw (hcwang@ccu.edu.tw)

This research aims to explore the potential application of this approach in the production of biosensor chips. The biosensor chip is utilized for the identification and examination of early-stage lung cancer cells. The findings of the optical microscope were corroborated by the field emission scanning electron microscopy, which provided further evidence that the growth of MoS 2 is uniform and that there is minimal disruption in the electrode, hence minimizing the likelihood of an open circuit creation. Furthermore, the bilayer structure of the produced MoS 2 has been validated through the utilization of Raman spectroscopy. A research investigation was undertaken to measure the photoelectric current generated by three various types of clinical samples containing lung cancer cells, specifically the CL1, NCI-H460, and NCI-H520 cell lines. The findings from the empirical analysis indicate that the coefficient of determination (R-Square) for the linear regression model was approximately 98%. Furthermore, the integration of a double-layer MoS 2 film resulted in a significant improvement of 38% in the photocurrent, as observed in the device's performance.

关键词： Absorption coefficient Chemical vapor deposition Optical absorption Physical vapor deposition Scanning electron microscopy Thin films

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5th Anniversary Article: A Lesson from Plants: High-Speed Soft Robotic Actuators (Adv. Sci. 5/2020)

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Advanced Science 2020年第5期7卷 2070024-2070024页

作者： Richard Baumgartner Alexander Kogler Josef M. Stadlbauer Choon Chiang Foo Rainer Kaltseis Melanie Baumgartner Guoyong Mao Christoph Keplinger Soo Jin Adrian Koh Nikita Arnold Zhigang Suo Martin Kaltenbrunner Siegfried Bauer Soft Matter Physics Institute of Experimental Physics Johannes Kepler University Linz Altenberger Straße 69 Linz 4040 Austria Soft Materials Lab Linz Institute of Technology LIT Johannes Kepler University Linz Altenberger Straße 69 Linz 4040 Austria Institute of High Performance Computing A*STAR 1 Fusionopolis Way #16-16 Connexis Singapore 138632 Singapore Institute of Polymer Science Johannes Kepler University Linz Altenberger Straße 69 Linz 4040 Austria Department of Mechanical Engineering University of Colorado Boulder Boulder CO 80309 USA Materials Science and Engineering Program University of Colorado Boulder Boulder CO 80303 USA Department of Mechanical Engineering National University of Singapore Singapore 117575 Singapore John A Paulson School of Engineering and Applied Sciences Harvard University 29 Oxford Street Cambridge MA 02138 USA

Explosion of ping‐pong balls that is caused by the rapid inflation of an elastomer membrane. The illustrated ultrafast actuation is based on a plant‐inspired mechanical instability that occurs in natural rubber and can be remotely triggered, presented in article number https://***/10.1002/advs.201903391 by Martin Kaltenbrunner and co‐workers. These new types of high‐speed soft actuators have potential applications in object sorting or grasping.

关键词： bioinspired dielectric elastomer actuators coupled dielectric elastomer balloons snap-buckling snap-through instabilities soft robotics for high-speed actuation

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