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9th International Conference on Applied System Innovation, ICASI 2023

作者： Usman, Muhammad Lin, Chun-Ling Ming Chi University of Technology International Ph.D Program in Innovative Technology of Biomedical Engineering and Medical Devices New Taipei City Taiwan Ming Chi University of Technology Department of Electrical Engineering New Taipei City Taiwan

ISBN: (纸本)9798350398380

Fifteen novices completed a Zentangle task while their brain activity was measured with electroencephalography (EEG) and their concentration emotional state, stress, and anxiety levels were evaluated with questionnaires. The study found increased activity in theta, alpha, beta, and gamma ranges associated with relaxation, focus, and mental activity. Participants reported improved concentration, emotional state, and reduced stress and anxiety levels after completing the task, suggesting the potential of Zentangle to enhance cognitive and emotional well-being. © 2023 IEEE.

关键词： Electroencephalography

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Spectral Learning of Shared Dynamics Between Generalized-Linear Processes 38

Spectral Learning of Shared Dynamics Between Generalized-Lin...

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38th Conference on Neural Information Processing Systems, NeurIPS 2024

作者： Oganesian, Lucine L. Sani, Omid G. Shanechi, Maryam M. Ming Hsieh Department of Electrical and Computer Engineering University of Southern California Los AngelesCA United States Ming Hsieh Department of Electrical and Computer Engineering Thomas Lord Department of Computer Science Alfred E. Mann Department of Biomedical Engineering Neuroscience Graduate Program University of Southern California Los AngelesCA United States

Generalized-linear dynamical models (GLDMs) remain a widely-used framework within neuroscience for modeling time-series data, such as neural spiking activity or categorical decision outcomes. Whereas the standard usage of GLDMs is to model a single data source, certain applications require jointly modeling two generalized-linear time-series sources while also dissociating their shared and private dynamics. Most existing GLDM variants and their associated learning algorithms do not support this capability. Here we address this challenge by developing a multi-step analytical subspace identification algorithm for learning a GLDM that explicitly models shared vs. private dynamics within two generalized-linear time-series. In simulations, we demonstrate our algorithm's ability to dissociate and model the dynamics within two time-series sources while being agnostic to their respective observation distributions. In neural data, we consider two specific applications of our algorithm for modeling discrete population spiking activity with respect to a secondary time-series. In both synthetic and real data, GLDMs learned with our algorithm more accurately decoded one time-series from the other using lower-dimensional latent states, as compared to models identified using existing GLDM learning algorithms. © 2024 Neural information processing systems foundation. All rights reserved.

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Possible solutions for oxygenation support in critically ill patients with COVID-19

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Research on biomedical engineering 2021年第2期37卷 389-402页

作者： de Souza, Daniel Baldoino de Oliveira Andrade, Adriano Milagre, Selma Terezinha Pereira, Adriano Alves Centre for Innovation and Technology Assessment in Health Postgraduate Program in Electrical and Biomedical Engineering Faculty of Electrical Engineering Federal University of Uberlândia Uberlândia Brazil

Purpose: Due to the large number of patients with respiratory deficiency during the COVID-19 pandemic, several governments and their respective health care services have been studying ways to complement the care provided by offering immediate solutions. In view of this, the aim of this study was to carry out a systematic review of the advantages and disadvantages of possible solutions in oxygenation support. Methods: This systematic review used the PRISMA-P methodology and sought to list alternatives in oxygenation support that are being applied and studied worldwide. A bibliographic search was conducted in the MEDLINE and Cochrane Central databases, using the keywords SARS-CoV-2, COVID19, or coronavirus;combined with extracorporeal membrane oxygenation (ECMO), mechanical ventilation, mechanical ventilation support, low-cost, anesthesia, anesthesia machine, and ventilation therapy. The records were also found in the gray literature. Results: The search found 85 publications of which 41 articles were considered after excluding duplicate articles, reading the title and summary, and reading the articles in full. The oxygenation supports identified in these publications were the following: ECMO, shared mechanical ventilator, fast or low-cost production equipment, high-flow nasal cannula (HFNC), non-invasive ventilation, and use of anesthesia equipment as a mechanical ventilator. Conclusion: This study demonstrated the importance of a trained clinical team in the application of technologies. The alternatives found for support oxygenation require a more robust clinical evaluation to demonstrate their efficacy and safety for the COVID-19 patient. © 2021, Sociedade Brasileira de Engenharia Biomedica.

关键词： Oxygenation

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Computational Modeling of the Pendulum Test to Simulate Spasticity in the Elbow Joint 9th

Computational Modeling of the Pendulum Test to Simulate Spas...

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9th Latin American Congress on biomedical engineering, CLAIB 2022 and 28th Brazilian Congress on biomedical engineering, CBEB 2022

作者： Pasqualin, B.R. Silva, V.A. Orselli, M.I.V. Manffra, E.F. Pontifícia Universidade Católica do Paraná Biomedical Engineering Curitiba Brazil Pontifícia Universidade Católica do Paraná Postgraduate Program in Health Technology Curitiba Brazil Instituto Vita São Paulo Brazil

ISBN: (纸本)9783031494062

Computational models have been developed to help understand phenomena such as spasticity. In this study, we aim to develop a computational model using the Matlab-OpenSim interface to simulate the passive pendulum test in the elbow joint and evaluate whether the input of a neural excitation pattern with spasticity in the model would be sufficient to reproduce an altered kinematic pattern during an elbow pendulum test. We built a model with two segments that represent the humerus and radius bones, added two actuators to represent the biceps and triceps muscles, and the excitation values were obtained from the electromyography signal available in the literature. For the first simulation we used the electromyography (EMG) signal from a non-spastic person and for the last simulation was used the excitation values from a person with mild spasticity. Our results showed that it is possible to reproduce the pendulum test at the elbow joint, but modifications in the model are necessary to better reproduce the movement. © 2024, The Author(s), under exclusive license to Springer Nature Switzerland AG.

关键词： MATLAB

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Characterization of Electroencephalography (EEG) Responses to Musical Stimuli 3

Characterization of Electroencephalography (EEG) Responses t...

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3rd International Congress of biomedical engineering and Bioengineering, CIIBBI 2024

作者： Rojas Tocora, Angelica Maria Muller, Oliver Orjuela-Canon, Alvaro D. Ortiz, Victor A. Universidad Del Rosario - Escuela Colombiana de Ingeniería Biomedical Engineering Program Julio Garavito D.C. Bogota Colombia School of Medicine and Health Sciences Universidad Del Rosario D.C. Bogota Colombia Unversidad Tecnologica de Pereira Engineering Faculty Pereira Colombia

ISBN: (纸本)9798331532352

This study investigates the effects of different musical genres on electroencephalographic (EEG) responses in healthy subjects. The EEG technique was analyzed for five different music styles, such as classical, rock, jazz, vallenato, and urban, and in this way, to determine the influence in brainwave patterns. For instance, classical music was linked to alpha brainwave patterns associated with relaxation, while genres like rock and reggaeton are associated with beta patterns, indicating of concentration and mental activity. The study also explores how intrinsic factors such as musical lyrics and individual differences like musical training and preferences impact brain activity. Findings suggest that music can evoke strong emotional responses and activate different brain regions depending on the genre and individual factors. This complexity underscores the importance of considering personal and cultural aspects in understanding the neural dynamics of musical experiences. © 2024 IEEE.

关键词： Electrophysiology

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Investigating the effect of cerebral atrophy on brain deformation using subject-specific models

Investigating the effect of cerebral atrophy on brain deform...

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Medical Imaging 2023: biomedical Applications in Molecular, Structural, and Functional Imaging

作者： Hong, Allen Carass, Aaron Zuo, Lianrui Prince, Jerry L. Alshareef, Ahmed Department of Biomedical Engineering The College of New Jersey EwingNJ08618 United States Department of Electrical and Computer Engineering Johns Hopkins University BaltimoreMD21218 United States Laboratory of Behavioral Neuroscience National Institute on Aging National Institutes of Health BaltimoreMD20892 United States Biomedical Engineering Program University of South Carolina ColumbiaSC29208 United States

ISBN: (纸本)9781510660410

Traumatic brain injuries (TBIs) are a major health risk that increases with age. Natural brain aging results in cerebral atrophy and the enlargement of the ventricular regions. The objective of this study is to investigate the effect of cerebral atrophy on brain biomechanics with subject-specific models to determine the risk of traumatic brain injury (TBI). Utilizing subjects from a longitudinal study of aging in healthy volunteers, we created subject-specific brain models of a small cohort with progressive age-related cerebral atrophy. We then simulate concussive loading conditions to study changes in brain deformation, a correlate to risk of TBI. The results display differing trends with increasing ventricle volume, with some subjects exhibiting increases and others showing decreasing strain. Additional subject simulations are needed to clarify these the causes of these trends. © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

关键词： Health risks

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Foot hemodynamics using optical tomography: A potential biomarker of peripheral arterial disease

Foot hemodynamics using optical tomography: A potential biom...

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2023 Advances in Science and engineering Technology International Conferences, ASET 2023

作者： Al Abdi, Rabah M. Zakaria, Amer Al Nashash, Hasan Zalak, Tasnim Goswami, Nandu Jeet, Vishwa Jordan Univ. of Science and Tech. Dept. of Biomedical Engineering Irbid Jordan American University of Sharjah Dept. of Electrical Engineering Sharjah United Arab Emirates American University of Sharjah Master of Science in Biomedical Engineering Program Sharjah United Arab Emirates College of Medicine Mohammed Bin Rashed University of Medicine and Health Sciences Dubai United Arab Emirates

ISBN: (纸本)9781665454742

Peripheral arterial disease (PAD) is the narrowing of the arteries within the lower extremities, which inhibits blood flow to the foot. We present the use of dynamic diffuse optical tomography (DDOT) system to measure blood flow in the foot during venous and arterial occlusions. DDOT is a non-ionizing, contrast-free, and fast imaging modality. The DDOT system consists of 4 sensors, each containing four laser diodes (at wavelengths of 670, 780, 808, and 850 nm) and two silicon photodiodes. We examined 11 healthy subjects with a protocol consisting of five consecutive measurements. Biomarkers were extracted from changes in hemoglobin concentrations during the measurements. The results from a pilot study are presented in this report. The average increase in total hemoglobin was 17.2 ±5.8 μ M during a measurement with 60 mmHg occlusion and 10.4 ± 6.7 μ M during a measurement with 180 mmHg occlusion. The biomarkers can quantify blood perfusion and oxygen consumption in the foot, and they have the potential to detect and monitor PAD. © 2023 IEEE.

关键词： Hemodynamics

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Microwave dielectric and structural characteristics in Li2O-B2O3-SiO2 glass ceramics

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Ceramics International 2025年第16期51卷 22925-22931页

作者： Qiu, Jun-Yan Tu, Chi-Shun Huang, Szu-Ting Li, Yongxiang Chen, Pin-Yi Chen, Cheng-Sao Montecillo, Rhys Feng, Kuei-Chih International Ph.D. Program in Innovative Technology of Biomedical Engineering and Medical Devices Ming Chi University of Technology New Taipei City Taiwan Department of Physics Fu Jen Catholic University New Taipei City Taiwan Department of Mechanical Engineering Ming Chi University of Technology New Taipei City Taiwan School of Engineering RMIT University MelbourneVIC3000 Australia Research Center for Intelligent Medical Devices Ming Chi University of Technology New Taipei City Taiwan Department of Mechanical Engineering Hwa Hsia University of Technology New Taipei City Taiwan

Advancements in high-frequency communication devices have emphasized miniaturization and low energy consumption. This work focuses on developing microwave dielectric materials characterized by an ultra-low dielectric constant and low dielectric loss coefficient. In this study, B2O3 and Li2O were added into the SiO2 matrix to form the LBS glass-ceramics. The B2O3-added SiO2 shows a formation of α-cristobalite phase, and the Li2O additive in the B2O3-SiO2 glass-ceramics sintered at 900 °C reveal a primary quartz phase with a secondary phase Li2Si2O5, that partially transformed into Li2SiO3 in the specimen sintered at 950 °C. The LBS12 (x = 12 wt%) show stronger Raman peaks of Li2Si2O5 and Li2SiO3, indicating increase of highly-crystallized Si-O network. As the quartz phase diminishes, Li2Si2O5 and Li2SiO3 begin to develop in the glass-ceramic matrix. Dense microstructures and well-formed crystalline grains were observed in the LBS glass-ceramics. The quality factors were primarily affected by grain size and density. The Li2Si2O5 additive in the LBS glass-ceramics can reduce dielectric permittivity (Εr) and increase Q × f, particularly at higher frequencies. A low Εr of 4.7–5, a high Q × f of 2600 GHz, and a hardness of 249 MHV were achieved in the LBS12 sintered at 900 °C. These LBS glass-ceramics exhibit potential for use in low-temperature co-fired ceramic (LTCC) applications in high-frequency communication devices. © 2025

关键词： Sintering

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Design and Feasibility Test of In-House Indirect Perfusion Bioreactor for 3-D Cell Culture 15

Design and Feasibility Test of In-House Indirect Perfusion B...

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15th biomedical engineering International Conference, BMEiCON 2023

作者： Suwannaphan, T. Tharasanit, T. Wongpakham, T. Pimpin, A. Chessadangkul, K. King Mongkut's University of Technology North Bangkok Department of Mechanical Engineering Technology Bangkok Thailand Faculty of Veterinary Science Chulalongkorn University Department of Obstetrics Gynaecology and Reproduction Bangkok Thailand Chulalongkorn University Faculty of Engineering Department of Mechanical Engineering Bangkok Thailand Chulalongkorn University Biomedical Engineering Program Faculty of Engineering Bangkok Thailand

ISBN: (纸本)9798350345247

Selection of bioreactor system depends on many factors such as type of products, process of culture, and product density. No standard for development methodology is available nowadays. This work demonstrated the development of multi mini-chamber indirect perfusion bioreactor to support 3-D cell culture. The systems consisted of scaffolds, cell/scaffold retainers, culture tanks with a single peristaltic pump. Flow simulation was conducted to investigate the effects of flow rate and inlets/outlets' position on the distribution of shear stresses on the cell/scaffold cassettes installed inside the bioreactor. The prototype with 4 culture tanks connected in series was tested for long period operation. Lastly, preliminary experiments to culture and differentiate pig muscle stem cells were conducted. The results showed that muscle cells were successfully differentiated both on glass slides and aloe vera scaffolds inside the developed bioreactor. © 2023 IEEE.

关键词： Flow simulation

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Feasibility Study of Finger Interface for Miniature Surgical Instruments

Feasibility Study of Finger Interface for Miniature Surgical...

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Telepresence, IEEE Conference on

作者： Serin Cha Sebin Kim Seok Chang Ryu BioRobotics Laboratory Department of Mechanical and Biomedical Engineering Graduate Program in Smart Factory Ewha Womans University Seoul South Korea BioRobotics Laboratory Department of Mechanical and Biomedical Engineering Ewha Womans University Department of Mechanical and Biomedical Engineering BioRobotics Laboratory Ewha Womans University

ISBN: (数字)9798331528249

ISBN: (纸本)9798331528256

This paper presents a study on the design of a finger interface to improve the teleoperation of a miniaturized surgical instrument with a bendable distal section. A unique design principle employing the kinematic similarity between the human motion and the follower robot has been proposed for such instruments, which may result in embodied teleoperation, enhancing the overall telepresence experience. According to the principle, a design for an index finger interface was proposed, consisting of a sub-unit measuring finger motion and a handle. When the interface is connected to a robotic platform, it can control the entire tool motion in two separate ways: distal bending by the sub-unit and overall tool motion by the handle. A human subject test was conducted for trajectory-following tasks in a virtual environment, and their performance score was quantified for analysis of the learning curve. Based on the satisfactory learning rate of 75.78% for all nine subjects, the proposed finger interface could be a promising interface for a miniature surgical instrument with a long bendable section at the distal end.

关键词： Telepresence Instruments Fingers Virtual environments Kinematics Bending Motion measurement Robots

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