The objectives of this study were to visually examine the surface and interior morphology of a new class of biodegradable hydrogels based on dextran-methacrylate and to quantify the porous structure of these hydrogels...
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The retropulsive momentum induced by a laser calculi lithotriptor was evaluated by high-speed photography. Calculus phantoms made from plaster of paris were placed in a clear glass tube that served as in vitro model o...
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The retropulsive momentum induced by a laser calculi lithotriptor was evaluated by high-speed photography. Calculus phantoms made from plaster of paris were placed in a clear glass tube that served as in vitro model of the ureter. Movement of the calculus was monitored by a high-speed camera which had provided pictures in every 300μsecond. It was found that the recoil momentum proportionally increased with increasing laser energy and larger fiber diameter resulted in higher momentum.
A previous 2D ultrasound study (R.A. Malkin et al., 2001) suggested that there is relaxation of the myocardium after defibrillation. However, that 2D study could not measure activity occurring within the first 33 ms f...
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A previous 2D ultrasound study (R.A. Malkin et al., 2001) suggested that there is relaxation of the myocardium after defibrillation. However, that 2D study could not measure activity occurring within the first 33 ms following the shock. Thus, the objective of our study is to determine the left ventricular (LV) geometry during this period. Biphasic defibrillation shocks were delivered to seven dogs. 1D short-axis ultrasound images of the LV cavity were acquired, the boundary of the anterior and posterior endocardial walls was extracted and the distance between them computed from 32 ms before to 32 ms after the shock. The normalized mean pre- and post-shock slopes were 0.2 /spl plusmn/ 2.2 and 3.3 /spl plusmn/ 7.9 %/10 ms, respectively. The post-shock LV diameter slope is positive in the first 32 ms following both successful and unsuccessful defibrillation shocks (p<0.05). Therefore, our results confirm that the bulk of the myocardium is relaxing immediately after a defibrillation shock.
This paper describes the characterization and optimization of a reusable DNA microsensor array for rapid biological agent detection developed in previous publications. (Fig.l) [1-3] This MEMS based DNA sensor utilizes...
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Five decades of histological, electrophysiological, pharmacological and biochemical investigations exist, but relatively little is known regarding the ionic mechanisms underlying the action potential variations in the...
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Five decades of histological, electrophysiological, pharmacological and biochemical investigations exist, but relatively little is known regarding the ionic mechanisms underlying the action potential variations in the ventricle associated with healthy and disease conditions. The computational modelling in murine ventricular myocytes can complement our knowledge of the experimental data and provide us with more quantitative descriptions in understanding different conditions related to normal and disease conditions. This paper initially reviews the theoretical modelling for cardiac ventricular action potentials of various species and the related experimental work. It then focuses on the progress of computational modelling of cardiac ventricular cells for normal, diabetic and spontaneously hypertensive rats. Also presented is the recent modelling efforts of the action potential in mouse ventricular cells. The computational insights gained into the ionic mechanisms in rodents will enhance our understanding of the heart and provide us with new knowledge for future studies to treat cardiac diseases in children and adults.
NST support is provided principally in the form of grants awarded on a competitive basis under a rigorous peer review process; NSF does not conduct research itself. In 1992, NSF defined a project eligible for support ...
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ISBN:
(纸本)0780364651
NST support is provided principally in the form of grants awarded on a competitive basis under a rigorous peer review process; NSF does not conduct research itself. In 1992, NSF defined a project eligible for support as bioengineering research as one "...with diagnosis or treatment-related goals, that applies engineering principles to problems in biology and medicine while advancing engineering knowledge is eligible for support. Bioengineering research to aid persons with disabilities is also eligible". Bioengineering at NSF has two defined programs: 1. "Biochemical engineering", and 2. a two-component activity "biomedicalengineering" (BME) and "Research to Aid Persons with Disabilities" (RAPD). The material that follows describes the Undergraduate and Graduate Design Projects, which is part of the RAPD component of the bioengineeringprogram.
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