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The International Conference on Advances in Chemical Technologies for Water and Wastewater Treatment

作者： Dul-Sun KIM Jae-Suk SHIN Sung-Jin KIMAND Dong-Keun LEE Dept.of Chemical Engineering Environmental Biotechnology National Core Research CenterEnvironmental and Regional Development InstituteBK21 Graduate Education Program for Environmental Core TechnologyGRETECKorea Gyeongsang National UniversityKajwa-dong 900JinjuGyeongnam 660-701Republic of Korea

A constructed wetland was designed to remove BOD together with total nitrogen（T-N）from municipal *** designed wetland was composed of the aerobic tank and anaerobic/anoxic one which was connected in series immediately after the aerobic one,and could treat 100 m raw municipal wastewater every *** biological oxidation and nitrification could be obtained at the aerobic *** than 80 % of BOD5 and 30.5 % of T-N was removed at the aerobic tank,and more than 96 % of the organic nitrogen and ammonia nitrogen were nitrified successfully into nitrate nitrogen,which is indicative of the successful biological *** removal of BOD and T-N could be obtained at the anaerobic/anoxic tank of the constructed *** 57 % of the remaining BOD was removed at the anaerobic/anoxic *** than 74 % of the remaining T-N was denitrified,and the average concentration of T-N at the final effluent was 6.9 mg/*** maximum available capacity for nutrient uptake in plants was far less（of the order of 5 %）than the loading rate of nutrients to the constructed wetland.

关键词： Aerated constructed wetland Municipal wastewaters Nutrients Biological nitrification

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Direct evidence of a heterotrimeric complex of human interleukin-4 with its receptors

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Protein Science 2008年第2期6卷

作者： Ross C. Hoffman Beverly J. Castner Mary Gerhart Marylou G. Gibson Brian D. Rasmussen Carl J. March James Weatherbee Monica Tsang Alla Gustchina Celine Schalk-Hihi Ludmila Reshetnikova Alexander Wlodawer Immunex Corporation Seattle Washington 98101 Biotechnology Division R&D Systems 614 McKinley Place N.E. Minneapolis Minnesota 55413 Macromolecular Structure Laboratory NCI-Frederick Cancer Research and Development Center ABL-Basic Research Program Frederick Maryland 21702

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ANTIOXIDATIVE ACTIVITIES OF GELATIN HYDROLYSATE PREPARED FROM FARMED GIANT CATFISH (PANGASIANODON GIGAS) SKIN

ANTIOXIDATIVE ACTIVITIES OF GELATIN HYDROLYSATE PREPARED FRO...

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第十四届世界食品科技大会

作者： Akkasit Jongjareonrak Saroat Rawdkuen Manat Chaiian Sootwat Benjakul Wonnop Visessanguan Kazufumi Osako Munehiko Tanaka Nutraceutical and Functional Food Research and Development Center Faculty of Agro-Industry Prince of Songkla University Hat Yai Songkhla 90112 Thailand Food Technology Program School of Agro-Industry Mae Fah Luang University Muang Chiang Rai 57100 Thailand Department of Food Technology School of Agricultural Technology Walailak University Thasala Nakhon Si Thammarat 80160 Thailand Department of Food Technology Faculty of Agro-Industry Prince of Songkla University Hat Yai Songkhla 90112 Thailand National Center for Genetic Engineering and Biotechnology National Science and Technology Development Agency 113 Paholyothin Rd. Klong 1Klong Luang Pathumthani 12120 Thailand Department of Food Science and Technology Tokyo University of Marine Science and Technology Konan 4Minato Tokyo 108-8477 Japan

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A Large Therizinosauroid(Dinosauria:Theropoda) from the Early Cretaceous of Northwestern China

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Acta Geologica Sinica(English Edition) 2007年第4期81卷 539-549页

作者： LI Daqing PENG Cuo YOU Hailu Matthew C. LAMANNA Jerald D. HARRIS Kenneth J. LACOVARA ZHANG Jianping China University of Geosciences School of Earth Sciences and Resources Beijing 100083 P. R. China Fossil Research and Development Center of the Third Geology and Mineral Resources Exploration Academy of Gansu Province Lanzhou Gansu Province 730050 P. R. China Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 P. R. China Section of Vertebrate Paleontology Carnegie Museum of Natural History Pittsburgh Pennsylvania 15213 USA Dixie State College Science Building Utah 84770 USA Paleontology and Geology Program Department of Bioscience and Biotechnology Drexel University Philadelphia Pennsylvania 19104 USA

We herein describe an associated partial postcranial skeleton of a theropod dinosaur discovered in the Lower Cretaceous Xinminpu Group of the Yujingzi Basin, in the Jiuquan area of Gausu Province, northwestern China. Features of its humerus, such as strongly expanded proximal and distal ends, a well developed medial tuberosity, distal condyles expressed on the humeral cranial surface, and a hypertrophied entepicondyle, definitively establish the therizinosauroid affinities of the specimen. It differs from other therizinosauroids in having a shallow, poorly demarcated glenoid fossa with a prominent rounded and striated tumescence on the dorsomedial surface of its scapular portion, and a pubis with a strongly concave cranial margin. It represents a new taxon, Suzhousaurus megatherioides gen. et sp. nov. Cladistic analysis recovers Suzhousaurus as the sister taxon of Nothronychus mckinleyi from the mid-Cretaceous of western North America; together, they are basal members of the Therizinosauroidea, more derived than the Early Cretaceous Falcarius and Beipiaosaurus but less derived than Alxasaurus and the Therizinosauridae. Along with ＂Nanshiungosaurus＂ bohlini from possibly coeval beds in the Mazongshan area of northern-most Gansu, Suzhousaurus represents one of the largest-known Early Cretaceous therizinosauroids, demonstrating that this clade attained considerable body size early in its evolutionary history.

关键词： Dinosauria Theropoda Therizinosauroidea Yujingzi Basin Early Cretaceous Jiuquan area Gansu Province China

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Plant-Derived Vaccines: A New Approach to International Public Health

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Journal of Food Science 2008年第1期69卷

作者： CHARLES J. ARNTZEN RICHARD T. M AHONEY About the authors: Charles Arntzen was appointed to the Florence Ely Nelson Presidential Endowed Chair at Arizona State Univ. in Tempe in 2000. He also serves as the Founding Director of the Arizona Biomedical Institute. Prior to joining ASU Dr. Arntzen was the president and CEO of the Boyce Thompson Institute for Plant Research in Ithaca New York. He has served on many national and international committees including service as Chairman of the National Institutes of Health's Biotechnology Policy Board and as Chair of the Biobased Industrial Products Committee for the National Academy of Sciences. He was elected to the US National Academy of Sciences in 1983 and to the National Academy of India the following year. He currently serves as a member of President George W. Bush's Council of Advisors on Science & Technology. Richard Mahoney joined the faculty of Arizona State Univ. in 2002 and with Dr. Arntzen is the co-founder of the proVacs (production of Vaccines using Applied Crop Science) Center. He has been an international pioneer in public sector management of intellectual property and in policy issues related to the global introduction of vaccines. He formerly served as Vice President of PATH (the Program for Appropriate Technology in Health Seattle Washington) as chairman of the International Task Force on Hepatitis B Immunization and as co-founder and Chief Development and Administrative Officer of IVI (the International Vaccine Institute Seoul Korea). He has spent the past 15 years focusing on vaccine production and supply issues and has identified intellectual property as a crucial element in assuring vaccine supply to the developing world. Based upon this experience he was the architect of recently created the Center for Management of Intellectual Property in Health R&D (MIHR) program which is based in London England. Their mailing address is: Arizona Biomedical Institute Arizona State Univ. PO Box 871601 Tempe AZ 85287-1601 USA.

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Two-stage false contour detection algorithm using re-quantization and directional contrast features and its application to adaptive false contour reduction

Two-stage false contour detection algorithm using re-quantiz...

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IEEE International Conference on Consumer Electronics (ICCE)

作者： Ji Won Lee Bo Ra Lim Rae-Hong Park Jae Seung Kim Wonseok Ahn Department of EE Sogang University Seoul South Korea Interdisciplinary Program of Integrated Biotechnology Sogang University Seoul South Korea Digital Media Research & Development Center Samsung Electronics Company Limited Suwon South Korea

This paper proposes a two-stage false contour detection algorithm using re-quantization and directional contrast features, with application to false contour reduction. In the first stage of false contour detection, smooth regions are first removed by bit-depth reduction and re-quantization. In the second stage, false contours are separated from edge or texture regions using directional contrast features, yielding the false contour detection map that shows possible candidate regions of false contours. For false contour reduction, adaptive directional smoothing filtering is applied only to candidate regions that are specified by the false contour detection map. Therefore the proposed algorithm is able to preserve sharp edges and details. Computer simulation with a large number of test images shows the effectiveness of the proposed algorithm

关键词： Detection algorithms Image edge detection Smoothing methods Digital TV Pixel Adaptive filters Filtering Computer simulation Testing Computer displays

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Elongation of C16:0 to C18:0 fatty acids in methylotrophic yeastHansenula polymorphaCBS 1976 and fatty acid auxotrophic mutants

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FEMS Microbiology Letters 2006年第2期237卷

作者： Wanida Wongsumpanchai Sarintip Anamnart Kobkul Laoteng Amorn Petsom Program of Biotechnology Faculty of Science Chulalongkorn University Bangkok 10330 Thailand The Institute of Biotechnology and Genetic Engineering Chulalongkorn University Bangkok 10330 Thailand Biochemical Engineering and Pilot Plant Research and Development Unit National Center for Genetic Engineering and Biotechnology (BIOTEC) at King Mongkut's University of Technology Thonburi Bangkuntien Bangkok 10150 Thailand

Fatty acid elongation defective mutant was isolated from the ethyl methanesulfonate treated Hansenula polymorpha based on the growth ability. Using biochemical and genetic approaches, the mutant was characterized. When compared with the fatty acid phenotype of the parental strain, the differences in profile and content of fatty acids in V1 mutant were found. In this V1 mutant, polyunsaturated fatty acids, linoleic and α-linolenic acids, could not be detected with a corresponding increase in the content of mono-unsaturated fatty acids. The ratio of C16/C18 fatty acids revealed that the accumulation of C16 fatty acids was increased significantly. The experiments on fatty acid supplementation indicated that the mutant required C18:0 for the proper growth. The results of genetic complementation with the elongase genes of Saccharomyces cerevisiae confirmed that the lesion was occurred at least in the extension of C16:0 to C18:0 of V1. The H. polymorpha mutant obtained in this work will be used as a useful tool for unraveling the pathway of fatty acid synthesis and the role of fatty acids on biological processes.

关键词： Elongase Fatty acid Hansenula polymorpha Saturated fatty acid auxotrophic mutant

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Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. (vol 69, pg 3350, 2004)

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JOURNAL OF ORGANIC CHEMISTRY 2004年第18期69卷 6156-6156页

作者： Hwang, BY Su, BN Chai, HB Mi, QW Kardono, LBS Afriastini, JJ Riswan, S Santarsiero, BD Mesecar, AD Wild, R Fairchild, CR Vite, GD Rose, WC Farnsworth, NR Cordell, GRA Pezzuto, JM Swanson, SM Kinghorn, AD Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy College of Pharmacy University of Illinois at Chicago Chicago Illinois 60612 Research and Development Chemistry Indonesian Institute of Science Serpong 15310 Tangerang Indonesia Herbarium Bogoriense Research and Development Center for Biology Indonesian Institute of Science 16122 Bogor Indonesia Center for Pharmaceutical Biotechnology and the Department of Medicinal Chemistry and Pharmacognosy University of Illinois at Chicago Illinois 60607 and Bristol-Myers Squibb Pharmaceutical Research Institute P.O. Box 4000 Princeton New Jersey 08543

Two cytotoxic rocaglate derivatives possessing an unusual dioxanyloxy unit, silvestrol (1) and episilvestrol (2), were isolated from the fruits and twigs ofAglaia silvestrisby bioassay-guided fractionation monitored with a human oral epidermoid carcinoma (KB) cell line. Additionally, two new baccharane-type triterpenoids, 17,24-epoxy-25-hydroxybaccharan-3-one (3) and 17,24-epoxy-25-hydroxy-3-oxobaccharan-21-oic acid (4), as well as eleven known compounds, 1β,6α-dihydroxy-4(15)-eudesmene (5), ferulic acid (6), grasshopper ketone (7), apigenin, cabraleone, chrysoeriol, 1β,4β-dihydroxy-6α,15α-epoxyeudesmane, 4-hydroxy-3-methoxyacetophenone, 4-hydroxyphenethyl alcohol, ocotillone, and β-sitosterol 3-O-β-d-glucopyranoside, were also isolated and characterized. The structures of compounds1−4were elucidated by spectroscopic studies and by chemical transformation. The absolute stereochemistry of silvestrol (1) was established by a X-ray diffraction study of its di-p-bromobenzoate derivative, and the structure of3was also confirmed by single-crystal X-ray diffraction. The isolates and chemical transformation products were evaluated for cytotoxicity against several human cancer cell lines, and silvestrol (1) and episilvestrol (2) exhibited potent in vitro cytotoxic activity. Silvestrol (1) was further evaluated in vivo in the hollow fiber test and in the murine P-388 leukemia model.

关键词： Reaction products Stereochemistry Carbon Cells Toxicity

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Deliniation of the Ex Vivo Culture Conditions Supporting the Long-Term Engraftment of Cord Blood CD34+ Cells.

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Blood 2004年第11期104卷 4954-4954页

作者： Ronald L. Brown J. Zhang L. Qiu A. Nett G. Almeida-Porada R. Herzig E.D. Zanjani Research and Development Quality Biological Inc Gaithersburg MD USA Blood and Marrow Transplant Program James Graham Brown Cancer Center Louisville KY USA Animal Biotechnology University of Nevada Reno NV USA

Ex-vivo expansion regimens for cord blood (CB) CD34+ cells that maintain their long term engrafting ability hold great promise for adult transplantation but have been met with relatively little success. Data presented delineate the development of a cell cu1ture system composed of clinical grade serum-free medium (QBSF 60) and a cytokine combination that not only yields large numbers of CD34+ cell populations but also supports the long term engraftment of these cells. CBCD34+ cells were cultured for over 14 days in QBSF 60 medium supplemented with the following cytokine combination a.) SCF, Flt-3 and TPO, b.) SCF, Flt-3 and IL-6, c.) SCF, Flt-3 TPO and IL-3, d.) SCF Flt-3, TPO and IL-6, e.) SCF, Flt-3, TPO and IL-11, f.) SCF, Flt-3, TPO, IL-3, IL-6 and IL-11, g.) SCF, Flt-3, TPO, IL-3, IL-6, IL-11, G-CSF, and EPO. The following cytokine concentrations was used for each of the above combinations: SCF (50 ng/ml), Flt-3 (100 ng/ml), TPO (100 ng/ml), IL-3 (20 ng/ml), IL-6 (50 ng/ml), IL-11 (50 ng/ml), G-CSF (50 ng/ml) and EPO (10U), or 10 times lower concentrations of each cytokine. The ex vivo cultured were evaluated for the following cell populations: total nucleated cells, CD34+ cells, CD34+ CD38− cells, CFU-C, HPP-CFU, and LTC-IC. In all cases those combinations of cytokines containing either IL-3 and/or IL-6 yielded higher quantities of all the cellular populations studied. Those culture conditions having the fewest cytokines that yielded large quantities of total cells, CD34+ cells and/or CD34+ CD38− cells were subsequently examined after 14 days of culture for their long-term engrafting ability in the fetal sheep model for human hematopoiesis. Typically, after 14 days of ex vivo culture CD34+ cells fail to engraft long-term, therefore, all our cultures were maintained for at least this time frame. Based on these criteria, CD34+ cells cultured in the presence of the higher concentration of cytokines a, b d and f were examined. The cultured CD 34+ cells from all fou

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developmental Characteristics of Diadegma semiclausum Hellen (Hymenoptera: Ichneumonidae), a Larval Parasitoid of Plutella xylostella L. (Lepidoptera: Yponomeutidae)

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Journal of Asia-Pacific Entomology 2003年第1期6卷 105-110页

作者： Kwon, Min Park, Kang-Ryong Kwon, Hye-Jin Highland Crop Research Div. National Highland Agricultural Experiment Station Rural Development Administration Pyeongchang 232-955 South Korea Entomology Program Graduate School of Agricultural Biotechnology Seoul National University Suwon 441-744 South Korea

Some developmental characteristics of a larval-parasitoid ichneumonid, Diadegma semiclausum Hellen, donated from Asian Vegetable research and development Center (AVRDC), Taiwan, in 2001, were investigated to utilize as a biological control agent of diamondback moth (DBM), Plutella xylostella L. As a preliminary test for rearing the prey insect, we selected the most preferable host plant for oviposition. Among five host plants tested, DBM female laid the highest number of eggs on the aluminum foil prepared with radish leaf juice, followed by rape, Chinese cabbage, broccoli and common cabbage. The developmental periods for the whole larval stage of D. semiclausum and DBM were 12.3 days and 14.2 days at 23°C, respectively. Also, parasitoid cocoons could be stored at 8°C for 24.5 days without a significant loss of viability. The DBM pupa, however, lasted for approximately four weeks at 8°C. The percent parasitism to DBM was 70.8% on average, and the sex ratio of D. semiclausum adults was slightly male-biased, 0.94:1. The seasonal fluctuation of DBM density showed apparently two generations, and the peak periods occurred in middle June and middle July. © 2003 Korean Society of Applied Entomology, Taiwan Entomological Society and Malaysian Plant Protection Society.

关键词： Chinese cabbage developmental period Diadegma semiclausum oviposition preference parasitism Plutella xylostella

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