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检索条件"机构=Program in Computational Biology and Bioinformatics"
525 条 记 录,以下是431-440 订阅
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The ABCs of Experimental Evolution
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International Scholarly Research Notices 2013年 第1期2013卷
作者: Zaid Abdo Mathew Stein Andrzej Wojtowicz Kim M. Pepin Departments of Statistics University of Idaho Moscow ID 83844 USAuidaho.edu Department of Mathematics University of Idaho Moscow ID 83844 USAuidaho.edu Program of Bioinformatics and Computational Biology (BCB) University of Idaho Moscow ID 83844 USAuidaho.edu USDA-ARS South Atlantic Area 950 College Station Road Athens GA 30605-2720 USA Department of Computer Engineering University of Idaho Moscow ID 83844 USAuidaho.edu Micron Technology Inc. Boise ID 83716 *** Department of Animal Sciences Washington State University Pullman WA 99164 USAwsu.edu Fogarty International Center National Institutes of Health 31 Center Drive MSC 2220 Bethesda MD 20892-2220 USAfic.nih.gov Department of Biology Colorado State University Campus Delivery 1878 Fort Collins CO 80523 USAcolostate.edu
Microbial evolution is complex and is influenced by many sources of variation. Experimental evolution is no exception, although it is more controlled, easily replicated, and typically devoid of interactions between sp...
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Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers
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Nature genetics 2023年 第6期55卷 1078页
作者: Yuan Yuan Young Seok Ju Youngwook Kim Jun Li Yumeng Wang Christopher J Yoon Yang Yang Inigo Martincorena Chad J Creighton John N Weinstein Yanxun Xu Leng Han Hyung-Lae Kim Hidewaki Nakagawa Keunchil Park Peter J Campbell Han Liang Department of Bioinformatics and Computational Biology The University of Texas MD Anderson Cancer Center Houston TX USA. Cancer Genome Project Wellcome Trust Sanger Institute Hinxton UK. Graduate School of Medical Science and Engineering Korea Advanced Institute of Science and Technology Daejeon Korea. Department of Health Science and Technology Samsung Advanced Institute for Health Science and Technology Sungkyunkwan University School of Medicine Seoul Korea. Samsung Genome Institute Samsung Medical Center Seoul Korea. Quantitative and Computational Biosciences Graduate Program Baylor College of Medicine Houston TX USA. Division of Biostatistics The University of Texas Health Science Center at Houston School of Public Health Houston TX USA. Department of Medicine and Dan L. Duncan Cancer Center Division of Biostatistics Baylor College of Medicine Houston TX USA. Department of Systems Biology The University of Texas MD Anderson Cancer Center Houston TX USA. Department of Applied Mathematics and Statistics Johns Hopkins University Baltimore MD USA. Department of Biochemistry and Molecular Biology The University of Texas Health Science Center at Houston McGovern Medical School Houston TX USA. Department of Biochemistry Ewha Womans University School of Medicine Seoul Korea. Laboratory for Cancer Genomics RIKEN Center for Integrative Medical Sciences Yokohama Japan. Division of Hematology/Oncology Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea. kpark@skku.edu. Samsung Advanced Institute for Health Sciences and Technology Sungkyunkwan University School of Medicine Seoul South Korea. kpark@skku.edu. Cancer Genome Project Wellcome Trust Sanger Institute Hinxton UK. pc8@sanger.ac.uk. Department of Haematology University of Cambridge Cambridge UK. pc8@sanger.ac.uk. Department of Bioinformatics and Computational Biology The University of Texas MD Anderson Cancer Center Houston TX USA. hliang1@mdanderson.org. Quantitative and Comp
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40. Genomic profiling of lung adenocarcinomas with increased MET copy numbers
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Cancer Genetics 2018年 226卷 51-51页
作者: Liu, Ching-Hua (Ruby) Chen, Hui Fang, Lianghua Hu, Peter C. Gu, Jun Zhao, Jin Abraham, Ronald Yao, Hui Singh, Rajesh R. Jeffrey Medeiros, L. Luthra, Rajyalakshimi Lu, Xinyan Department of Hematopathology University of Texas MD Anderson Cancer Center Houston TX United States Master of Science in Diagnostic Genetics Program School of Health Professions University of Texas MD Anderson Cancer Center Houston TX United States Department of Pathology Northwestern University Feinberg School of Medicine Chicago IL United States Department of Pathology University of Texas MD Anderson Cancer Center Houston TX United States Department of Oncology Jiangsu Hospital of Traditional Chinese Medicine Nanjing Jiangsu China Department of Clinical Laboratory Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Shangsha Hunan China Department of Bioinformatics and Computational Biology University of Texas MD Anderson Cancer Center Houston TX United States
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Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
Research Square
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Research Square 2021年
作者: Zhang, Martin Jinye Hou, Kangcheng Pasaniuc, Bogdan Price, Alkes L. Dey, Kushal K. Jagadeesh, Karthik A. Weinand, Kathryn Sakaue, Saori Taychameekiatchai, Aris Rao, Poorvi Pisco, Angela Oliveira Zou, James Wang, Bruce Gandal, Michael Raychaudhuri, Soumya Harvard University United States Osaka University Japan Department of Epidemiology Harvard T.H. Chan School of Public Health BostonMA United States Program in Medical and Population Genetics Broad Institute of MIT and Harvard CambridgeMA United States Bioinformatics Interdepartmental Program University of California Los Angeles Los AngelesCA United States Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Department of Computational Medicine David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Center for Data Sciences Brigham and Women’s Hospital BostonMA United States Division of Genetics Department of Medicine Brigham and Women’s Hospital Harvard Medical School BostonMA United States Division of Rheumatology Inflammation and Immunity Department of Medicine Brigham and Women’s Hospital Harvard Medical School BostonMA United States Department of Biomedical Informatics Harvard Medical School BostonMA United States Department of Medicine and Liver Center University of California San Francisco San FranciscoCA United States Developmental and Stem Cell Biology Graduate Program University of California San Francisco San FranciscoCA United States Chan Zuckerberg Biohub San FranciscoCA United States Department of Electrical Engineering Stanford University Palo AltoCA United States Department of Biomedical Data Science Stanford University Palo AltoCA United States Department of Psychiatry David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Program in Neurobehavioral Genetics Semel Institute David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Versus Arthritis Centre for Genetics and Genomic
Gene expression at the individual cell-level resolution, as quantified by single-cell RNA-sequencing (scRNA-seq), can provide unique insights into the pathology and cellular origin of diseases and complex traits. Here... 详细信息
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Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
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Nature communications 2022年 第1期13卷 3471页
作者: Theodore P Braun Mariam Okhovat Cody Coblentz Sarah A Carratt Amy Foley Zachary Schonrock Brittany M Curtiss Kimberly Nevonen Brett Davis Brianna Garcia Dorian LaTocha Benjamin R Weeder Michal R Grzadkowski Joey C Estabrook Hannah G Manning Kevin Watanabe-Smith Sophia Jeng Jenny L Smith Amanda R Leonti Rhonda E Ries Shannon McWeeney Cristina Di Genua Roy Drissen Claus Nerlov Soheil Meshinchi Lucia Carbone Brian J Druker Julia E Maxson Knight Cancer Institute Oregon Health & Science University Portland OR 97239 USA. Division of Hematology and Medical Oncology Oregon Health & Science University Portland OR 97239 USA. Knight Cardiovascular Institute Oregon Health & Science University Portland OR 97239 USA. Program in Molecular and Cellular Biology Oregon Health & Science University Portland OR 97239 USA. Computational Biology Program Oregon Health & Science University Portland OR 97239 USA. Division of Bioinformatics and Computational Biology Oregon Health & Science University Portland OR 97239 USA. Clinical Research Division Fred Hutchinson Cancer Research Center 1100 Fairview Ave N Seattle WA 98109 USA. MRC Molecular Haematology Unit MRC Weatherall Institute of Molecular Medicine John Radcliffe Hospital Headley Way Oxford OX3 9DS UK. Division of Pediatric Hematology/Oncology University of Washington Seattle WA 98195 USA. Department of Molecular and Medical Genetics Oregon Health & Science University Portland OR 97239 USA. Howard Hughes Medical Institute Portland OR USA. Knight Cancer Institute Oregon Health & Science University Portland OR 97239 USA. maxsonj@ohsu.edu. Division of Hematology and Medical Oncology Oregon Health & Science University Portland OR 97239 USA. maxsonj@ohsu.edu.
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Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
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Nature communications 2022年 第1期13卷 7573页
作者: Wei Jiao Gurnit Atwal Paz Polak Rosa Karlic Edwin Cuppen Alexandra Danyi Jeroen de Ridder Carla van Herpen Martijn P Lolkema Neeltje Steeghs Gad Getz Quaid D Morris Lincoln D Stein Computational Biology Program Ontario Institute for Cancer Research Toronto ON Canada. Department of Molecular Genetics University of Toronto Toronto ON Canada. Vector Institute Toronto ON Canada. Broad Institute of MIT and Harvard Cambridge MA USA. Harvard Medical School Boston MA USA. Center for Cancer Research Massachusetts General Hospital Boston MA USA. Department of Oncological Sciences Icahn School of Medicine at Mount Sinai 15 1425 Madison Ave. New York NY USA. Bioinformatics Group Division of Molecular Biology Department of Biology Faculty of Science University of Zagreb Horvatovac 102a Zagreb Croatia. Hartwig Medical Foundation Science Park 408 Amsterdam The Netherlands. Center for Molecular Medicine and Oncode Institute University Medical Center Utrecht Utrecht The Netherlands. Center for Molecular Medicine University Medical Center Utrecht Utrecht The Netherlands. Radboud University Medical Center Nijmegen The Netherlands. Department of Medical Oncology Erasmus MC Cancer Institute University Medical Center Rotterdam Dr. Molewaterplein 40 3015 GD Rotterdam The Netherlands. Department of Medical Oncology The Netherlands Cancer Institute Plesmanlaan 121 1066 CX Amsterdam The Netherlands. Department of Pathology Massachusetts General Hospital Boston MA USA. University of Toronto Toronto ON Canada. Computational Biology Program Ontario Institute for Cancer Research Toronto ON Canada. lincoln.stein@***. Department of Molecular Genetics University of Toronto Toronto ON Canada. lincoln.stein@***.
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Patterns of somatic structural variation in human cancer genomes (vol 578, pg 112, 2020)
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NATURE 2023年 第7948期614卷 E38-E38页
作者: Li, Yilong Roberts, Nicola D. Wala, Jeremiah A. Shapira, Ofer Schumacher, Steven E. Kumar, Kiran Khurana, Ekta Waszak, Sebastian Korbel, Jan O. Haber, James E. Imielinski, Marcin Weischenfeldt, Joachim Beroukhim, Rameen Campbell, Peter J. Cancer Genome Project Wellcome Trust Sanger Institute Hinxton UK Totient Inc Cambridge MA USA Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Department of Haematology University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Korea Advanced Institute of Science and Technology Daejeon South Korea Department of Zoology Genetics and Physical Anthropology University of Santiago de Compostela Santiago de Compostela Spain Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) University of Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) University of Vigo Vigo Spain Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain Department of Zoology Genetics and Physical Anthropology (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) Universidade de Vigo Vigo Spain The Broad Institute of Harvard and MIT Cambridge MA USA Bioinformatics and Integrative Genomics Harvard University Cambridge MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Harvard Medical School Boston MA USA Massachusetts General Hospital Center for Cancer Research Charlestown MA USA Dana-Farber Cancer Institute Boston MA USA Department of Biostatistics and Computational Biology Dana-Farber Cancer Institute and Harvard Medical School Boston MA USA Weill Cornell Medical College New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine Ne
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Meeting Report from the Second "Minimum Information for Biological and Biomedical Investigations" (MIBBI) workshop
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Standards in genomic sciences 2010年 第3期3卷 259-66页
作者: Carsten Kettner Dawn Field Susanna-Assunta Sansone Chris Taylor Jan Aerts Nigel Binns Andrew Blake Cedrik M Britten Ario de Marco Jennifer Fostel Pascale Gaudet Alejandra González-Beltrán Nigel Hardy Jan Hellemans Henning Hermjakob Nick Juty Jim Leebens-Mack Eamonn Maguire Steffen Neumann Sandra Orchard Helen Parkinson William Piel Shoba Ranganathan Philippe Rocca-Serra Annapaola Santarsiero David Shotton Peter Sterk Andreas Untergasser Patricia L Whetzel Beilstein-Institut Frankfurt am Main Germany Centre for Ecology & Hydrology UK Oxford e-Research Centre University of Oxford UK The European Bioinformatics Institute (EBI) UK Faculty of Engineering - ESAT/SCD Leuven University Leuven-Heverlee Belgium Division of Pathway Medicine University of Edinburgh Medical School Edinburgh UK MRC Harwell UK Medical Department University Medical Center Johannes Gutenberg University-Mainz Mainz Germany Consortium for Genomic Technology Milano Italy University of Nova Gorica Nova Gorica Slovenia NIEHS NIH US National Toxicology Program USA Swiss Institute of Bioinformatics Geneva Switzerland Computational and Systems Medicine and Department of Computer Science University College London London UK Department of Computer Science Aberystwyth University Aberystwyth UK Center for Medical Genetics Ghent University Ghent Belgium Department of Plant Biology University of Georgia Athens USA Department of Stress- and Developmental Biology Institute for Plant Biochemistry Halle Germany Peabody Museum of Natural History Yale University New Haven USA Macquarie University Sydney Australia National University of Singapore Singapore Cancer Pharmacology The Mario Negri Institute for Pharmacological Research Milan Italy Image Bioinformatics Research Group Department of Zoology University of Oxford Oxford UK Wellcome Trust Sanger Institute UK Zentrum für Molekulare Biologie der Universität Heidelberg Heidelberg Germany The National Center for Biomedical Ontology / Stanford Center for Biomedical Informatics Research Stanford University Stanford USA
This report summarizes the proceedings of the second workshop of the 'Minimum Information for Biological and Biomedical Investigations' (MIBBI) consortium held on Dec 1-2, 2010 in Rüdesheim, Germany throu... 详细信息
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Correction to: Authors’ Reply to Letter to the Editor: Continued improvement to genetic diversity indicator for CBD
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Conservation Genetics 2021年 第4期22卷 537-539页
作者: Laikre, Linda Hohenlohe, Paul A. Allendorf, Fred W. Bertola, Laura D. Breed, Martin F. Bruford, Michael W. Funk, W. Chris Gajardo, Gonzalo González-Rodríguez, Antonio Grueber, Catherine E. Hedrick, Philip W. Heuertz, Myriam Hunter, Margaret E. Johannesson, Kerstin Liggins, Libby MacDonald, Anna J. Mergeay, Joachim Moharrek, Farideh O’Brien, David Ogden, Rob Orozco-terWengel, Pablo Palma-Silva, Clarisse Pierson, Jennifer Paz-Vinas, Ivan Russo, Isa-Rita M. Ryman, Nils Segelbacher, Gernot Sjögren-Gulve, Per Waits, Lisette P. Vernesi, Cristiano Hoban, Sean Division of Population Genetics Department of Zoology Stockholm University Stockholm Sweden Institute for Bioinformatics and Evolutionary Studies Department of Biological Sciences University of Idaho Moscow USA Division of Biological Sciences University of Montana Missoula USA City College of New York New York USA College of Science and Engineering Flinders University Bedford Park Australia School of Biosciences Cardiff University Cardiff Wales UK Graduate Degree Program in Ecology Department of Biology Colorado State University Fort Collins USA Universidad de Los Lagos Lab Genetics Aquaculture & Biodiversity Osorno Chile Instituto de Investigaciones en Ecosistemas y Sustentabilidad Universidad Nacional Autónoma de México Morelia Mexico School of Life and Environmental Sciences Faculty of Science The University of Sydney Sydney Australia School of Life Sciences Arizona State University Tempe USA INRAE Univ. Bordeaux Biogeco Cestas France U.S. Geological Survey Wetland and Aquatic Research Center Gainesville USA Department of Marine Sciences University of Gothenburg Tjärnö Strömstad Sweden School of Natural and Computational Sciences Massey University Auckland New Zealand The John Curtin School of Medical Research/Research School of Biology The Australian National University Acton Australia Research Institute for Nature and Forest Geraardsbergen Belgium Aquatic Ecology Evolution and Conservation KULeuven Leuven Belgium Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark Faculty of Biological Sciences Tarbiat Modares University Tehran Iran Scottish Natural Heritage Inverness UK Royal (Dick) School of Veterinary Studies and the Roslin Institute University of Edinburgh Midlothian UK Department of Plant Science Institute of Biology University of Campinas Campinas Brazil Australian Wildlife Conservancy Subiaco East Australia Laboratoire Evolution & Div
A correction to this paper has been published: https://***/10.1007/s10592-021-01376-9
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Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts
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The Lancet Respiratory Medicine 2020年 第7期8卷 696-708页
作者: Moll, Matthew Sakornsakolpat, Phuwanat Shrine, Nick Hobbs, Brian D DeMeo, Dawn L John, Catherine Guyatt, Anna L McGeachie, Michael J Gharib, Sina A Obeidat, Ma'en Lahousse, Lies Wijnant, Sara R A Brusselle, Guy Meyers, Deborah A Bleecker, Eugene R Li, Xingnan Tal-Singer, Ruth Manichaikul, Ani Rich, Stephen S Won, Sungho Kim, Woo Jin Do, Ah Ra Washko, George R Barr, R Graham Psaty, Bruce M Bartz, Traci M Hansel, Nadia N Barnes, Kathleen Hokanson, John E Crapo, James D Lynch, David Bakke, Per Gulsvik, Amund Hall, Ian P Wain, Louise Soler Artigas, María Jackson, Victoria E Strachan, David P Hui, Jennie James, Alan L Kerr, Shona M Polasek, Ozren Vitart, Veronique Marten, Jonathan Rudan, Igor Kähönen, Mika Surakka, Ida Gieger, Christian Karrasch, Stefan Rawal, Rajesh Schulz, Holger Deary, Ian J Harris, Sarah E Enroth, Stefan Gyllensten, Ulf Imboden, Medea Probst-Hensch, Nicole M Lehtimäki, Terho Raitakari, Olli T Langenberg, Claudia Luan, Jian'an Wareham, Nick Zhao, Jing Hua Hayward, Caroline Murray, Alison Porteous, David J Smith, Blair H Jarvelin, Marjo-Riitta Wielscher, Matthias Joshi, Peter K Kentistou, Katherine A Timmers, Paul RHJ Wilson, James F Cook, James P Lind, Lars Mahajan, Anubha Morris, Andrew P Ewert, Ralf Homuth, Georg Stubbe, Beate Weiss, Stefan Zeggini, Eleftheria Weiss, Scott T Silverman, Edwin K Dudbridge, Frank Tobin, Martin D Cho, Michael H Channing Division of Network Medicine Brigham and Women's Hospital Boston MA United States Division of Pulmonary and Critical Care Medicine Brigham and Women's Hospital Boston MA United States Department of Medicine Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand Genetic Epidemiology Group Department of Health Sciences University of Leicester Leicester United Kingdom Computational Medicine Core Center for Lung Biology Department of Medicine University of Washington Seattle WA United States Division of Pulmonary Critical Care and Sleep Medicine Department of Medicine University of Washington Seattle WA United States Cardiovascular Health Research Unit Department of Medicine University of Washington Seattle WA United States University of British Columbia Center for Heart Lung Innovation St Paul's Hospital Vancouver BC Canada Department of Epidemiology Erasmus Medical Centre Rotterdam Netherlands Department of Respiratory Medicine Erasmus Medical Centre Rotterdam Netherlands Department of Bioanalysis Faculty of Pharmaceutical Sciences Ghent University Ghent Belgium Department of Respiratory Medicine Ghent University Hospital Ghent Belgium Department of Medicine University of Arizona Tucson AZ United States GlaxoSmithKline Research and Development Collegeville PA United States Center for Public Health Genomics University of Virginia Charlottesville VA United States Department of Public Health Sciences University of Virginia Charlottesville VA United States Department of Public Health Sciences Graduate School of Public Health Seoul National University Seoul South Korea Interdisciplinary Program of Bioinformatics College of National Sciences Seoul National University Seoul South Korea Institute of Health and Environment Seoul National University Seoul South Korea Department of Internal Medicine Kangwon National University Chuncheon South Korea Department of Medicine and Department of Epidemiology Columbia Universit
Background: Genetic factors influence chronic obstructive pulmonary disease (COPD) risk, but the individual variants that have been identified have small effects. We hypothesised that a polygenic risk score using addi...
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