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Author Correction: Widespread exposure to SARS-CoV-2 in wildlife communities

Nature communications 2024年第1期15卷 6940页

作者： Amanda R Goldberg Kate E Langwig Katherine L Brown Jeffrey M Marano Pallavi Rai Kelsie M King Amanda K Sharp Alessandro Ceci Christopher D Kailing Macy J Kailing Russell Briggs Matthew G Urbano Clinton Roby Anne M Brown James Weger-Lucarelli Carla V Finkielstein Joseph R Hoyt Department of Biological Sciences Virginia Tech Blacksburg VA USA. Virginia Tech Carilion School of Medicine Virginia Tech Roanoke VA USA. Center for Emerging Zoonotic and Arthropod-borne Pathogens Virginia Tech Blacksburg VA USA. Molecular Diagnostics Laboratory Fralin Biomedical Research Institute Virginia Tech Roanoke VA USA. Department of Biomedical Sciences and Pathobiology Virginia Tech Blacksburg VA USA. Translational Biology Medicine and Health Graduate Program Virginia Tech Roanoke VA USA. Program in Genetics Bioinformatics and Computational Biology Virginia Tech Blacksburg VA USA. Department of Biochemistry Virginia Tech Blacksburg VA USA. Data Services University Libraries Virginia Tech Blacksburg VA USA. Virginia Tech Center for Drug Discovery Virginia Tech Blacksburg VA USA. Academy of Integrated Science Virginia Tech Blacksburg VA USA. Department of Biological Sciences Virginia Tech Blacksburg VA USA. finkielc@vt.edu. Virginia Tech Carilion School of Medicine Virginia Tech Roanoke VA USA. finkielc@vt.edu. Center for Emerging Zoonotic and Arthropod-borne Pathogens Virginia Tech Blacksburg VA USA. finkielc@vt.edu. Molecular Diagnostics Laboratory Fralin Biomedical Research Institute Virginia Tech Roanoke VA USA. finkielc@vt.edu. Virginia Tech Center for Drug Discovery Virginia Tech Blacksburg VA USA. finkielc@vt.edu. Academy of Integrated Science Virginia Tech Blacksburg VA USA. finkielc@vt.edu. Department of Biological Sciences Virginia Tech Blacksburg VA USA. hoytjosephr@***.

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Author Correction: Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing

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Nature communications 2020年第1期11卷 4499页

作者： Igor Mandric Jeremy Rotman Harry Taegyun Yang Nicolas Strauli Dennis J Montoya William Van Der Wey Jiem R Ronas Benjamin Statz Douglas Yao Velislava Petrova Alex Zelikovsky Roberto Spreafico Sagiv Shifman Noah Zaitlen Maura Rossetti K Mark Ansel Eleazar Eskin Serghei Mangul Department of Computer Science University of California Los Angeles 404 Westwood Plaza Los Angeles CA 90095 USA. Department of Clinical Pharmacy School of Pharmacy University of Southern California 1540 Alcazar Street Los Angeles CA 90033 USA. Bioinformatics Interdepartmental Ph.D. Program University of California Los Angeles 611 Charles E. Young Drive East Los Angeles CA 90095-1570 USA. Biomedical Sciences Graduate Program University of California San Francisco 1675 Owens Street Suite 310 San Francisco CA 94143-0523 USA. Department of Molecular Cell and Developmental Biology University of California Los Angeles 610 Charles E. Young Drive South Los Angeles CA 90095 USA. Department of Microbiology Immunology and Molecular Genetics University of California Los Angeles 609 Charles E. Young Drive East Los Angeles CA 90095 USA. Program in Bioinformatics and Integrative Genomics Harvard Medical School 10 Shattuck Street Suite 514 Boston MA 02115 USA. Wellcome Trust Sanger Institute Wellcome Genome Campus Hinxton Cambridge CB10 1SA UK. Department of Computer Science Georgia State University 33 Gilmer Street SE Atlanta GA 30303 USA. The Laboratory of Bioinformatics I.M. Sechenov First Moscow State Medical University Moscow 119991 Russia. Institute for Quantitative and Computational Biosciences University of California Los Angeles 611 Charles E. Young Drive East Los Angeles CA 90095 USA. Department of Genetics The Institute of Life Sciences The Hebrew University of Jerusalem Jerusalem 9190401 Israel. Department of Medicine University of California San Francisco 533 Parnassus Avenue San Francisco CA 94143 USA. Immunogenetics Center Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California Los Angeles 1000 Veteran Avenue Los Angeles CA 90095-1652 USA. Sandler Asthma Basic Research Center Department of Microbiology and Immunology University of California San Francisco 513 Parnass

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

关键词： computational biology and bioinformatics Adaptive immunity Immunogenetics B cells

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A Multi-Site Break through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib (Trial In Progress)

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Blood 2024年 144卷 4265.2-4265.2页

作者： Ghayas C. Issa Alexander J. Ambinder Wenbin Xiao Scott Manalis Alex K Shalek Lukasz P. Gondek Alex Kentsis Nicholas J. Short Naval Daver Jing Ning Lianchun Xiao Michael Hemann Ken Chen Keyur P. Patel Pavan Bachireddy Andrew A. Lane Marina Konopleva Omar Abdel-Wahab Jeffrey J. Molldrem Ross L Levine Jacqueline S. Garcia Department of Leukemia The University of Texas MD Anderson Cancer Center Houston TX Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore MD Department of Pathology and Laboratory Medicine Hematopathology Service Memorial Sloan Kettering Cancer Center New York NY Massachusetts Institute of Technology Cambridge MA Institute for Medical Engineering & Science and Department of Chemistry Massachusetts Institute of Technology Cambridge MA Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University School of Medicine Baltimore MD Tow Center for Developmental Oncology Department of Pediatrics Memorial Sloan Kettering Cancer Center New York NY MD Anderson Cancer Center Houston TX The University of Texas M.D. Anderson Cancer Center Houston TX Department of Biostatistics University of Texas MD Anderson Cancer Center Houston David H. Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Cambridge MA Department of Bioinformatics and Computational Biology The University of Texas MD Anderson Cancer Center Houston TX Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston TX Department of Hematopoietic Biology & Malignancy The University of Texas M.D. Anderson Cancer Center Houston TX Department of Medical Oncology Dana-Farber Cancer Institute Boston MA Albert Einstein College of Medicine Bronx NY Leukemia Service Department of Medicine Memorial Sloan Kettering Cancer Center New York NY Departments of Hematopoietic Biology and Malignancy The University of Texas MD Anderson Cancer Center Houston TX Human Oncology and Pathogenesis Program Memorial Sloan Kettering Cancer Center New York NY

Background and Significance: Measurable residual disease (MRD) represents the fundamental driver of relapse and mortality in acute myeloid leukemia (AML). However, there are currently no established approaches to address this unmet need. Our central hypothesis is that targeting vulnerabilities associated with specific leukemia genotypes will eradicate MRD and prevent disease relapse. Break Through Cancer is a collaboration between our centers aimed at making progress in the deadliest cancers by stimulating radical clinical and laboratory research collaboration. The menin-KMT2A interaction is a critical dependency in acute leukemias caused by rearrangement of the Lysine methyl transferase ( KMT2Ar ) or Nucleoporin 98 ( NUP98r ) genes, or mutation of the Nucleophosmin 1 gene ( NPM1mt ). Revumenib (previously SNDX-5613), is a potent, oral, selective inhibitor of this interaction with an established safety and efficacy in refractory leukemias with these genotypes (Issa GC, Nature 2023). Additionally, KMT2Ar or NPM1mt leukemias can undergo BCL2-dependent apoptosis, and dual Bcl-2 and menin inhibition led to synergistic activity in KMT2Ar or NPM1mt leukemia models (Carter BZ, Blood 2021; Fiskus W, BCJ 2022). Therefore, we designed this study investigating the combination of revumenib and venetoclax to eradicate MRD in these AML subtypes (NCT06284486). Study Design and Methods: This is a single arm, open label, multicenter, phase I/II investigator-initiated study. Patients (pts) age ≥ 12 years with weight ≥ 45Kg, and known history of NPM1mt , or KMT2Ar , or NUP98r AML with MRD ≥ 0.1% identified by multiparameter flow cytometry (MFC) using central testing would be eligible; no morphologic evidence of AML (blasts <5%) in first remission following high intensity therapy or at least 2 cycles of low intensity therapy, or in second remission following any therapy. Up to 12 pts will be enrolled on the phase I, using 3+3, with escalating doses of revumenib and a target dose of 163

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Serum and CSF metabolomics analysis shows Mediterranean Ketogenic Diet mitigates risk factors of Alzheimer's disease

npj metabolic health and disease

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npj metabolic health and disease 2024年第1期2卷 15页

作者： Annalise Schweickart Richa Batra Bryan J Neth Cameron Martino Liat Shenhav Anru R Zhang Pixu Shi Naama Karu Kevin Huynh Peter J Meikle Leyla Schimmel Amanda Hazel Dilmore Kaj Blennow Henrik Zetterberg Colette Blach Pieter C Dorrestein Rob Knight Suzanne Craft Rima Kaddurah-Daouk Jan Krumsiek Tri-Institutional Program in Computational Biology & Medicine Weill Cornell Medicine New York NY USA. Department of Physiology and Biophysics Weill Cornell Medicine Institute for Computational Biomedicine Englander Institute for Precision Medicine New York NY USA. Department of Neurology Mayo Clinic Rochester MN USA. Department of Pediatrics University of California San Diego La Jolla CA USA. Department of Microbiology New York University Grossman School of Medicine New York NY USA. Department of Biostatistics and Bioinformatics Duke University Durham NC USA. Tasmanian Independent Metabolomics and Analytical Chemistry Solutions (TIMACS) Hobart TAS Australia. Baker Heart and Diabetes Institute 75 Commercial Road Melbourne VIC Australia. Baker Department of Cardiovascular Research Translation and Implementation La Trobe University Bundoora VIC Australia. Department of Psychiatry and Behavioral Sciences Duke University Durham NC USA. Department of Psychiatry and Neurochemistry University of Gothenburg Gothenburg Sweden. Duke Molecular Physiology Institute Duke University Durham NC USA. Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San Diego La Jolla CA USA. Departments of Pediatrics Computer Science and Engineering Bioengineering University of California San Diego La Jolla CA USA. Department of Gerontology and Geriatric Medicine Wake Forest University School of Medicine Winston Salem NC USA. Duke Institute of Brain Sciences Duke University Durham NC USA. Department of Medicine Duke University Durham NC USA.

Alzheimer's disease (AD) is influenced by a variety of modifiable risk factors, including a person's dietary habits. While the ketogenic diet (KD) holds promise in reducing metabolic risks and potentially affecting AD progression, only a few studies have explored KD's metabolic impact, especially on blood and cerebrospinal fluid (CSF). Our study involved participants at risk for AD, either cognitively normal or with mild cognitive impairment. The participants consumed both a modified Mediterranean Ketogenic Diet (MMKD) and the American Heart Association diet (AHAD) for 6 weeks each, separated by a 6-week washout period. We employed nuclear magnetic resonance (NMR)-based metabolomics to profile serum and CSF and metagenomics profiling on fecal samples. While the AHAD induced no notable metabolic changes, MMKD led to significant alterations in both serum and CSF. These changes included improved modifiable risk factors, like increased HDL-C and reduced BMI, reversed serum metabolic disturbances linked to AD such as a microbiome-mediated increase in valine levels, and a reduction in systemic inflammation. Additionally, the MMKD was linked to increased amino acid levels in the CSF, a breakdown of branched-chain amino acids (BCAAs), and decreased valine levels. Importantly, we observed a strong correlation between metabolic changes in the CSF and serum, suggesting a systemic regulation of metabolism. Our findings highlight that MMKD can improve AD-related risk factors, reverse some metabolic disturbances associated with AD, and align metabolic changes across the blood-CSF barrier.

关键词： Diseases Metabolomics

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Polygenic risk modeling for prediction of epithelial ovarian cancer risk (vol 30, pg 349, 2021)

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EUROPEAN JOURNAL OF HUMAN GENETICS 2022年第5期30卷 630-631页

作者： Dareng, Eileen O. Tyrer, Jonathan P. Barnes, Daniel R. Jones, Michelle R. Yang, Xin Aben, Katja K. H. Adank, Muriel A. Agata, Simona Andrulis, Irene L. Anton-Culver, Hoda Antonenkova, Natalia N. Aravantinos, Gerasimos Arun, Banu K. Augustinsson, Annelie Balmana, Judith Bandera, Elisa V. Barkardottir, Rosa B. Barrowdale, Daniel Beckmann, Matthias W. Beeghly-Fadiel, Alicia Benitez, Javier Bermisheva, Marina Bernardini, Marcus Q. Bjorge, Line Black, Amanda Bogdanova, Natalia V. Bonanni, Bernardo Borg, Ake Brenton, James D. Budzilowska, Agnieszka Butzow, Ralf Buys, Saundra S. Cai, Hui Caligo, Maria A. Campbell, Ian Cannioto, Rikki Cassingham, Hayley Chang-Claude, Jenny Chanock, Stephen J. Chen, Kexin Chiew, Yoke-Eng Chung, Wendy K. Claes, Kathleen B. M. Colonna, Sarah Cook, Linda S. Couch, Fergus J. Daly, Mary B. Dao, Fanny Davies, Eleanor de la Hoya, Miguel de Putter, Robin Dennis, Joe DePersia, Allison Devilee, Peter Diez, Orland Ding, Yuan Chun Doherty, Jennifer A. Domchek, Susan M. Dork, Thilo du Bois, Andreas Durst, Matthias Eccles, Diana M. Eliassen, Heather A. Engel, Christoph Evans, Gareth D. Fasching, Peter A. Flanagan, James M. Fortner, Renee T. Machackova, Eva Friedman, Eitan Ganz, Patricia A. Garber, Judy Gensini, Francesca Giles, Graham G. Glendon, Gord Godwin, Andrew K. Goodman, Marc T. Greene, Mark H. Gronwald, Jacek Hahnen, Eric Haiman, Christopher A. Hakansson, Niclas Hamann, Ute Hansen, Thomas V. O. Harris, Holly R. Hartman, Mikael Heitz, Florian Hildebrandt, Michelle A. T. Hogdall, Estrid Hogdall, Claus K. Hopper, John L. Huang, Ruea-Yea Huff, Chad Hulick, Peter J. Huntsman, David G. Imyanitov, Evgeny N. Isaacs, Claudine Jakubowska, Anna James, Paul A. Janavicius, Ramunas Jensen, Allan Johannsson, Oskar Th. John, Esther M. Jones, Michael E. Kang, Daehee Karlan, Beth Y. Karnezis, Anthony Kelemen, Linda E. Khusnutdinova, Elza Kiemeney, Lambertus A. Kim, Byoung-Gie Kjaer, Susanne K. Komenaka, Ian Kupryjanczyk, Jolanta Kurian, Allison W. Kwong, Ava Lambrechts, Diether Larson, Melissa C. Lazaro, Conxi L University of Cambridge Centre for Cancer Genetic Epidemiology Department of Public Health and Primary Care Cambridge UK University of Cambridge Centre for Cancer Genetic Epidemiology Department of Oncology Cambridge UK Center for Bioinformatics and Functional Genomics Cedars-Sinai Medical Center Los Angeles CA USA Radboud University Medical Center Radboud Institute for Health Sciences Nijmegen The Netherlands Netherlands Comprehensive Cancer Organisation Utrecht The Netherlands The Netherlands Cancer Institute—Antoni van Leeuwenhoek hospital Family Cancer Clinic Amsterdam The Netherlands Veneto Institute of Oncology IOV—IRCCS Immunology and Molecular Oncology Unit Padua Italy Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital Fred A. Litwin Center for Cancer Genetics Toronto ON Canada University of Toronto Department of Molecular Genetics Toronto ON Canada University of California Irvine Department of Epidemiology Genetic Epidemiology Research Institute Irvine CA USA N.N. Alexandrov Research Institute of Oncology and Medical Radiology Minsk Belarus ‘Agii Anargiri’ Cancer Hospital Athens Greece University of Texas MD Anderson Cancer Center Department of Breast Medical Oncology Houston TX USA Lund University Department of Cancer Epidemiology Clinical Sciences Lund Sweden Vall d’Hebron Institute of Oncology Hereditary cancer Genetics Group Barcelona Spain University Hospital of Vall d’Hebron Department of Medical Oncology Barcelona Spain Rutgers Cancer Institute of New Jersey Cancer Prevention and Control Program New Brunswick NJ USA Landspitali University Hospital Department of Pathology Reykjavik Iceland University of Iceland BMC (Biomedical Centre) Faculty of Medicine Reykjavik Iceland University Hospital Erlangen Friedrich-Alexander-University Erlangen-Nuremberg Department of Gynecology and Obstetrics Comprehensive Cancer Center ER-EMN Erlangen Germany Vanderbilt University School of Medicine Division of Epidemiology Department

Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard approaches of PRS construction. Here, we implemented computationally efficient, penalized, logistic regression models (lasso, elastic net, stepwise) to individual level genotype data and a Bayesian framework with continuous shrinkage, “select and shrink for summary statistics” (S4), to summary level data for epithelial non-mucinous ovarian cancer risk prediction. We developed the models in a dataset consisting of 23,564 non-mucinous EOC cases and 40,138 controls participating in the Ovarian Cancer Association Consortium (OCAC) and validated the best models in three populations of different ancestries: prospective data from 198,101 women of European ancestries; 7,669 women of East Asian ancestries; 1,072 women of African ancestries, and in 18,915 BRCA1 and 12,337 BRCA2 pathogenic variant carriers of European ancestries. In the external validation data, the model with the strongest association for non-mucinous EOC risk derived from the OCAC model development data was the S4 model (27,240 SNPs) with odds ratios (OR) of 1.38 (95% CI: 1.28–1.48, AUC: 0.588) per unit standard deviation, in women of European ancestries; 1.14 (95% CI: 1.08–1.19, AUC: 0.538) in women of East Asian ancestries; 1.38 (95% CI: 1.21–1.58, AUC: 0.593) in women of African ancestries; hazard ratios of 1.36 (95% CI: 1.29–1.43, AUC: 0.592) in BRCA1 pathogenic variant carriers and 1.49 (95% CI: 1.35–1.64, AUC: 0.624) in BRCA2 pathogenic variant carriers. Incorporation of the S4 PRS in risk prediction models for ovarian cancer may have clinical utility in ovarian cancer prevention programs.

关键词： Clinical genetics Genetic markers Risk factors Biomedicine general Human Genetics bioinformatics Gene Expression Cytogenetics

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Correction to: Microbial function and genital inflammation in young South African women at high risk of HIV infection

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Microbiome 2022年第1期10卷 42页

作者： Arghavan Alisoltani Monalisa T Manhanzva Matthys Potgieter Christina Balle Liam Bell Elizabeth Ross Arash Iranzadeh Michelle du Plessis Nina Radzey Zac McDonald Bridget Calder Imane Allali Nicola Mulder Smritee Dabee Shaun Barnabas Hoyam Gamieldien Adam Godzik Jonathan M Blackburn David L Tabb Linda-Gail Bekker Heather B Jaspan Jo-Ann S Passmore Lindi Masson Division of Medical Virology Department of Pathology University of Cape Town Cape Town 7925 South Africa. Division of Biomedical Sciences University of California Riverside School of Medicine Riverside CA 92521 USA. Computational Biology Division Department of Integrative Biomedical Sciences University of Cape Town Cape Town 7925 South Africa. Division of Chemical and Systems Biology Department of Integrative Biomedical Sciences University of Cape Town Cape Town 7925 South Africa. Division of Immunology Department of Pathology University of Cape Town Cape Town 7925 South Africa. Centre for Proteomic and Genomic Research Cape Town 7925 South Africa. Laboratory of Human Pathologies Biology Department of Biology and Genomic Center of Human Pathologies Mohammed V University Rabat Morocco. Institute of Infectious Disease and Molecular Medicine (IDM) University of Cape Town Cape Town 7925 South Africa. Centre for Infectious Diseases Research (CIDRI) in Africa Wellcome Trust Centre University of Cape Town Cape Town 7925 South Africa. Seattle Children's Research Institute University of Washington Seattle WA 98101 USA. Bioinformatics Unit South African Tuberculosis Bioinformatics Initiative Stellenbosch University Stellenbosch 7602 South Africa. DST-NRF Centre of Excellence for Biomedical Tuberculosis Research Stellenbosch University Stellenbosch 7602 South Africa. Desmond Tutu HIV Centre University of Cape Town Cape Town 7925 South Africa. Centre for the AIDS Programme of Research in South Africa Durban 4013 South Africa. National Health Laboratory Service Cape Town 7925 South Africa. Division of Medical Virology Department of Pathology University of Cape Town Cape Town 7925 South Africa. Lindi.Masson@burnet.edu.au. Institute of Infectious Disease and Molecular Medicine (IDM) University of Cape Town Cape Town 7925 South Africa. Lindi.Masson@burnet.edu.au. Centre for the AIDS Programme of Research in South Africa Durban 4013 South Africa. Lindi.Ma

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Author Correction: Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative

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Genome medicine 2022年第1期14卷 128页

作者： Ruth Johnson Yi Ding Vidhya Venkateswaran Arjun Bhattacharya Kristin Boulier Alec Chiu Sergey Knyazev Tommer Schwarz Malika Freund Lingyu Zhan Kathryn S Burch Christa Caggiano Brian Hill Nadav Rakocz Brunilda Balliu Christopher T Denny Jae Hoon Sul Noah Zaitlen Valerie A Arboleda Eran Halperin Sriram Sankararaman Manish J Butte Clara Lajonchere Daniel H Geschwind Bogdan Pasaniuc Department of Computer Science University of California Los Angeles Los Angeles CA 90095 USA. ruthjohnson@g.ucla.edu. Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. ruthjohnson@g.ucla.edu. Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. Bioinformatics Interdepartmental Program University of California Los Angeles Los Angeles CA 90095 USA. Department of Oral Biology School of Dentistry University of California Los Angeles Los Angeles CA 90095 USA. Institute for Quantitative and Computational Biosciences David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. Department of Medicine Division of Cardiology University of California Los Angeles Los Angeles CA 90095 USA. Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. Department of Genetics Stanford School of Medicine Stanford CA 94305 USA. Molecular Biology Institute David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. Program in Neurogenetics Department of Neurology David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. Department of Computer Science University of California Los Angeles Los Angeles CA 90095 USA. Department of Computational Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA. Division of Hematology/Oncology Department of Pediatrics Gwynne Hazen Cherry Memorial Laboratories University of California Los Angeles Los Angeles CA 90095 USA. Molecular Biology Institute University of California Los Angeles Los Angeles CA 90095 USA. Jonsson Comprehensive Cancer Center University of California Los Angeles Los Angeles CA 90095

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Author Correction: Lipid exposure activates gene expression changes associated with estrogen receptor negative breast cancer

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NPJ breast cancer 2023年第1期9卷 11页

作者： Shivangi Yadav Ranya Virk Carolina H Chung Mariana Bustamante Eduardo David VanDerway Duojiao Chen Kirsten Burdett Hongyu Gao Zexian Zeng Manish Ranjan Gannon Cottone Xiaoling Xuei Sriram Chandrasekaran Vadim Backman Robert Chatterton Seema Ahsan Khan Susan E Clare Department of Surgery Feinberg School of Medicine Northwestern University Chicago IL 60611 USA. Department of Biomedical Engineering Northwestern University Evanston IL 60208-2850 USA. Department of Biomedical Engineering University of Michigan Ann Arbor MI 48109 USA. Center of for Medical Genomics Indiana University School of Medicine Indianapolis IN 46202 USA. Department of Preventive Medicine Northwestern University Chicago IL 60611 USA. Department of Data Sciences Dana Farber Cancer Institute Harvard T.H. Chan School of Public Health Boston MA 02215 USA. Program in Chemical Biology University of Michigan Ann Arbor MI 48109 USA. Rogel Cancer Center University of Michigan Medical School Ann Arbor MI 48109 USA. Center for Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI 48109 USA. Department of Obstetrics and Gynecology Northwestern University Feinberg School of Medicine Chicago IL 60611 USA. Department of Surgery Feinberg School of Medicine Northwestern University Chicago IL 60611 USA. s-khan2@northwestern.edu. Department of Surgery Feinberg School of Medicine Northwestern University Chicago IL 60611 USA. susan.clare@northwestern.edu.

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Author Correction: Differential peripheral immune signatures elicited by vegan versus ketogenic diets in humans

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Nature medicine 2024年第6期30卷 1785页

作者： Verena M Link Poorani Subramanian Foo Cheung Kyu Lee Han Apollo Stacy Liang Chi Brian A Sellers Galina Koroleva Amber B Courville Shreni Mistry Andrew Burns Richard Apps Kevin D Hall Yasmine Belkaid Metaorganism Immunity Section Laboratory of Host Immunity and Microbiome National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA. verena.link@nih.gov. NIH Center for Human Immunology National Institutes of Health Bethesda MD USA. verena.link@nih.gov. Bioinformatics and Computational Biosciences Branch Office of Cyber Infrastructure and Computational Biology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA. NIH Center for Human Immunology National Institutes of Health Bethesda MD USA. Center for Cellular Engineering Department of Transfusion Medicine Clinical Center National Institutes of Health Bethesda MD USA. Metaorganism Immunity Section Laboratory of Host Immunity and Microbiome National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA. Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH USA. National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health Bethesda MD USA. NIAID Microbiome Program National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA. National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health Bethesda MD USA. kevinh@niddk.nih.gov. Metaorganism Immunity Section Laboratory of Host Immunity and Microbiome National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA. ybelkaid@niaid.nih.gov. NIH Center for Human Immunology National Institutes of Health Bethesda MD USA. ybelkaid@niaid.nih.gov.

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Correction: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

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Genome medicine 2023年第1期15卷 38页

作者： Gabriella Assante Sriram Chandrasekaran Stanley Ng Aikaterini Tourna Carolina H Chung Kowsar A Isse Jasmine L Banks Ugo Soffientini Celine Filippi Anil Dhawan Mo Liu Steven G Rozen Matthew Hoare Peter Campbell J William O Ballard Nigel Turner Margaret J Morris Shilpa Chokshi Neil A Youngson Institute of Hepatology Foundation for Liver Research 111 Coldharbour Lane London SE5 9NT UK. Faculty of Life Sciences and Medicine King's College London London UK. Program in Chemical Biology University of Michigan Ann Arbor MI 48109 USA. Center for Bioinformatics and Computational Medicine Ann Arbor MI 48109 USA. Department of Biomedical Engineering University of Michigan Ann Arbor MI 48109 USA. Rogel Cancer Center University of Michigan Medical School Ann Arbor MI 48109 USA. Wellcome Trust Sanger Institute Cambridge UK. UNSW Sydney Sydney Australia. Cellular Bioenergetics Laboratory Victor Chang Cardiac Research Institute Darlinghurst NSW Australia. Institute of Liver Studies King's College Hospital London UK. Programme in Cancer and Stem Cell Biology Duke-NUS Medical School Singapore Singapore. CRUK Cambridge Institute Cambridge UK. Department of Medicine University of Cambridge Addenbrooke's Hospital Cambridge UK. Department of Ecology Environment and Evolution La Trobe University Bundoora Melbourne VIC 3086 Australia. Institute of Hepatology Foundation for Liver Research 111 Coldharbour Lane London SE5 9NT UK. n.youngson@researchinliver.org.uk. Faculty of Life Sciences and Medicine King's College London London UK. n.youngson@researchinliver.org.uk. UNSW Sydney Sydney Australia. n.youngson@researchinliver.org.uk.

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