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TaxDiff: taxonomic-guided diffusion model for protein sequence generation

Science China(Information Sciences) 2025年第4期68卷 385-386页

作者： Zongying LIN Hao LI Liuzhenghao LV Yu WANG Bin LIN Junwu ZHANG Zijun CHEN Calvin Yu-Chian CHEN Li YUAN Yonghong TIAN School of Electronic and Computer Engineering Peking University AI for Science (AI4S)-Preferred Program Peking University Shenzhen Graduate School Peng Cheng Laboratory School of Chemical Biology and Biotechnology Peking University

Protein design aims to generate protein variants with targeted biological functions, which is significant in multiple biological areas, including enzyme reaction catalysis, vaccine design, and fluorescence intensity. Protein design contains two paradigms: sequence generation and structure generation. Recently, EvoDiff [1] proposed a universal designing paradigm, combining structure and sequence generation using the diffusion framework, which improves the protein design efficiency.

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Designed harmonic step filter automatic control system to improve power quality and electric efficiency

Designed harmonic step filter automatic control system to im...

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2024 International Conference on Power Electronics and Energy System, ICPEES 2024

作者： Pasaribu, Faisal Irsan Sara, Ira Devi Tarmizi, Tarmizi Nasaruddin, Nasaruddin Doctoral Program School of Engineering Universitas Syiah Kuala Aceh23111 Indonesia Department Electrical and Computer Engineering Universitas Syiah Kuala Aceh23111 Indonesia

Good power quality and high-power efficiency are important aspects of power system management. Harmonic, as an unwanted frequency component in electrical signals, can interfere with power quality and reduce electrical efficiency. A passive harmonic filter is a device used to reduce or filter harmonics in electrical power systems. This research proposes technology Internet of Things with an automatic control system that moves the step filter to solve the harmonic problem, with the aim of improving the quality of power and electrical efficiency. The step filter functions to identify and isolate the harmonic, thus enabling appropriate controls to suppress the impact of the harmonic. The proposed system uses sophisticated control algorithms using sensors that can read current, voltage, frequency, and power factor to adjust the step filter parameters dynamically, following changes in load conditions and harmonizing. Simulation of the control network using the proteus software is subsequently undertaken in further research to design the control device. Using an automatic control set in the control simulation results reduced the need for manual intervention and let the system adjust the step filter automatically in response to changing network conditions. This showed that this method worked to lower harmonic distortion, increases the power factor through the filter used, and make the system more energy efficient overall. The study emphasizes the importance of applying sophisticated control strategies to manage harmonics efficiently, which ultimately paves the way to a cleaner and more reliable power grid. © Published under licence by IOP Publishing Ltd.

关键词： Power quality

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Asynchronous I/O Persistence for In-Memory Database Servers: Leveraging io_uring to Optimize Redis Persistence 17th

Asynchronous I/O Persistence for In-Memory Database Servers:...

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17th International Conference on Cloud Computing, CLOUD 2024, Held as Part of the Services Conference Federation, SCF 2024

作者： Chen, Le-Gao Li, Yanzhi Laohakangvalvit, Tipporn Sugaya, Midori Innovative Global Program College of Engineering Shibaura Institute of Technology Tokyo Koto City Japan Department of Computer Science and Engineering College of Engineering Shibaura Institute of Technology Tokyo Koto City Japan

ISBN: (纸本)9783031771521

With constant hardware improvements allowing for increasingly large memory sizes, in-memory database servers have become an attractive option for various cloud applications. Even though in-memory database servers store all data in memory, there is still a need to persist data onto an I/O device for maintenance, updates, or protection against server crashes. In high throughput environments, persistence happens often, significantly hindering server throughput performance. Although popular in-memory database servers such as Redis or Dragonfly DB have adopted asynchronous I/O for socket operations, none have extended this approach for persistence. This results in significantly longer time taken for persistence, leading to prolonged reduced throughput. Given the recent introduction of io_uring, which has demonstrated significant performance improvements over past asynchronous I/O APIs, we have decided to implement it into Redis to evaluate its effectiveness in reducing these performance overheads. Our findings indicate that io_uring can significantly enhance performance in use cases with medium to large payload sizes but may hinder performances in use cases involving small payload sizes due to higher complexity and higher operation cost per datapoint. This method can likely be applied to other servers, such as Dragonfly DB and Memcached, to achieve similar benefits in appropriate scenarios. Additionally, in-memory database server persistence can serve as valuable benchmarks for further io_uring development and optimization. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

关键词： Benchmarking

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Analysis of Parallel Graph Applications 30

Analysis of Parallel Graph Applications

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30th IEEE International Conference on Parallel and Distributed Systems, ICPADS 2024

作者： Atik, Funda Yesil, Serif Ouarnoughi, Hamza Niar, Smail Ozturk, Ozcan Washington University in St. Louis Computer Science and Engineering Department DoimukhMI United States NVidia UrbanaIL United States Université Polytechnique Hauts-de-France Department of Computer Science Valenciennes France LAMIH/CNRS Université Polytechnique Hauts-de-France Valenciennes France Sabanci University Computer Science and Engineering Program Electronics Engineering Program Istanbul Turkey

ISBN: (纸本)9798331515966

Despite the increasing computing power of shared memory systems with high core counts, parallel graph processing frameworks cannot exploit it effectively. The reason behind this is the inherent challenges in parallel graph algorithms, which are efficient management of dynamically created tasks and irregular data access patterns. In this paper, we categorize several popular design choices into three design dimensions: (i) execution mode, (ii) data access pattern, and (iii) work activation. We provide their high-level parallel implementations and analyze various implementations of three representative iterative graph algorithms by considering these design dimensions. To gain a better understanding of design choices, we examine their impacts on performance, communication, scalability, and work efficiency. We also investigate the communication characteristics of the design choices on two state-of-the-art shared-memory platforms by performing micro-architectural analysis. Our microarchitectural analysis reveals that a topology-driven, pull-based model gives up to 20 x better performance. © 2024 IEEE.

关键词： Communication Graph Analytics Parallel Frameworks Performance Shared Memory Systems

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Dynamic Sampling-Based Meta-Learning Using Multilingual Acoustic Data for Under-Resourced Speech Recognition

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IEEE Access 2024年 12卷 106070-106083页

作者： Hsieh, I-Ting Wu, Chung-Hsien Zhao, Zhe-Hong National Cheng Kung University Graduate Program of Multimedia Systems and Intelligent Computing Tainan70101 Taiwan National Cheng Kung University Department of Computer Science and Information Engineering Tainan70101 Taiwan

Under-resourced automatic speech recognition (ASR) has become an active field of research and has experienced significant progress during the past decade. However, the performance of under-resourced ASR trained by existing methods is still far inferior to high-resourced ASR for practical applications. In this paper, speech data from languages that share the most phonemes with the under-resourced language are selected as supplementary resources for meta-training based on the Model-Agnostic Meta-Learning (MAML) strategy. Besides supplementary language selection, this paper proposes a dynamic sampling method instead of the original random sampling method to select support and query sets for each task in MAML to improve meta-training performance. In this study, Taiwanese is selected as the under-resourced language, and the speech corpus of five languages, including Mandarin, English, Japanese, Cantonese, and Thai, are chosen as supplementary training data for acoustic model training. The proposed dynamic sampling approach uses phonemes, pronunciation, and speech recognition models as the basis to determine the proportion of each supplementary language to select helpful utterances for MAML. For evaluation, with the selected utterances from each supplementary language for meta-training, we obtained a Word Error Rate of 20.24% and a Syllable Error Rate of 8.35% for Taiwanese ASR, which were better than the baseline model (26.18% and 13.99%) using only the Taiwanese corpus and other methods. © 2013 IEEE.

关键词： Speech recognition

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A Pulse Width Modulation-Based Spike Generator to Eliminate Timing Errors in Spiking Neural Networks

A Pulse Width Modulation-Based Spike Generator to Eliminate ...

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2025 International Conference on Electronics, Information, and Communication, ICEIC 2025

作者： Jo, Jungkook Sim, Keonhee Sim, Sangwoong Jun, Jaehoon Inha University Dept. of electrical and computer engineering and program in semiconductor convergence Incheon Korea Republic of Inha University Dept. of electrical engineering Incheon Korea Republic of

ISBN: (纸本)9798331510756

This paper proposes a novel spike generator for processing in memory (PIM) technology. Most of the electronics today utilize a von Neumann architecture. The von Neumann architecture suffers from the separation of memory and processor. This architecture delays data transfer between memory and processor. To overcome the issues, we utilize the spiking neural network (SNN) that combines memory and processor. SNN can be classified into voltage-based, current-based, and time-based architectures, each with its own pros and cons. Time-based SNN suffers from timing issues. To address the timing sensitivity of time-based neuron SNN, this paper proposes a PWM-based SNN. The PWM-based SNN utilizes pulse width-based logic to overcome timing sensitivity. © 2025 IEEE.

关键词： Pulse width modulation

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Mobility-Aware Federated Learning-Based Proactive UAVs Placement in Emerging Cellular Networks

IEEE Transactions on Machine Learning in Communications and ...

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IEEE Transactions on Machine Learning in Communications and Networking 2024年 2卷 1305-1318页

作者： Manzoor, Sanaullah Shakir, Muhammad Zeeshan Hasna, Mazen O. Qaraqe, Khalid A. University of the West of Scotland School of Computing Engineering and Physical Sciences PaisleyG72 0LH United Kingdom Qatar University College of Engineering Doha Qatar Texas A and M University Electrical and Computer Engineering Program Doha Qatar

With the vast proliferation of smart mobile devices, there is an ever-increasing demand for higher data rates and seamless connectivity throughout. Current 5th generation and beyond (B5G) cellular networks struggle to eradicate outage zones and ensure seamless connectivity. One promising solution to this problem is the use of unmanned aerial vehicles (UAVs) to assist the traditional ground network and provide connectivity in places where there are no small base stations or faulty ones as a result of some natural disasters such as flooding. In this paper, we propose a novel users' mobility-aware & users' demand-aware federated learning-based proactive UAV placement (MFPUP) framework to assist the existing ground communication network and minimise overall network outages. Our MFPUP framework utilises the federated learning-based mobility prediction model that recommends the potential outage areas to deploy UAVs using user-UAV association techniques such as the optimum association approach (OAP) and the greedy association approach (GAP). In order to validate the performance of the proposed MFPUP scheme we carried out extensive simulations. The proposed LSTM-based mobility model outperforms the DNN model with 92.88% prediction accuracy. Further, our results show that the proposed MFPUP framework associates the optimal number of users to UAVs while also improving 1.25 times users' downlink rates as compared other UAVs placement schemes. © 2023 CCBY.

关键词： Aircraft accidents

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Giant phonon-skyrmion coupling in ferromagnet/heavy metal heterostructures

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Physical Review B 2024年第6期110卷 064423-064423页

作者： Egor Savostin Vitaliy Lomakin Program in Materials Science and Engineering Center for Memory and Recording Research Department of Electrical and Computer Engineering

The strong impact of the strain-induced Dzyaloshinskii-Moriya interaction (SIDMI) on the magnetization dynamics of skyrmions in nanomagnetic structures is demonstrated. The effects of SIDMI are characterized by skyrmion equations (SEs) of motion and magnetoelastic (ME) equations. The study is performed on a model system of MgO/CoFe/Pt stacked on a piezoelectric substrate. The results demonstrate a major nonlinear amplification in both the first- and higher-harmonic magnitudes of the skyrmion breathing mode due to SIDMI. Remarkably, this enhancement can trigger a skyrmion collapse, enabling its deletion with ultraweak strain-induced excitations. The SIDMI effect is shown to be much more significant than the conventional ME effect. These findings open different avenues for the efficient manipulation of nanomagnetic structures through strain.

关键词： Exchange interaction Magnetic interactions Magnetization dynamics Magnetoacoustic effect Micromagnetism Spin dynamics

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An Extended Euclidean Algorithm Implementation over Ciphertext Space 2nd

An Extended Euclidean Algorithm Implementation over Ciphert...

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2nd International Conference on Security and Information Technologies with AI, Internet Computing and Big-data Applications, SITAIBA 2023

作者： Chi, Po-Wen Lin, Yuan-Pang Wang, Ming-Hung Chuang, Yun-Hsin Department of Computer Science and Information Engineering National Taiwan Normal University Taiwan Taipei Taiwan Department of Computer Science and Information Engineering National Chung Cheng University Taiwan Chiayi Taiwan Engineering Management Graduate Program College of Engineering National Cheng Kung University Taiwan Tainan Taiwan

ISBN: (纸本)9789819777853

Fully homomorphic encryption (FHE) is a useful cryptographic primitive. It makes a third-party manipulate data in the ciphertext space and therefore is a key technology for privacy-preserving outsourcing services. Theoretically, FHE can evaluate any circuits. However, the implementation is not trivial. The reason it lacks lots of basic operations like conditional check and branch control. In this paper, we focus on extended Euclidean algorithm operation over FHE. We introduce the problems we encounter and show how we solve these issues. We implement our design and evaluate its performance on a real computer. Finally, we propose some research directions for our future work. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Ciphertext

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Crafting chirality in three dimensions via a novel fabrication technique for bound states in the continuum metasurfaces

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Light(Science & Applications) 2024年第3期13卷 390-392页

作者： Zaid Haddadin Anna My Nguyen Lisa V.Poulikakos Department of Electrical&Computer Engineering University of California San DiegoLa JollaCAUSA Department of Mechanical&Aerospace Engineering University of California San DiegoLa JollaCAUSA Program of Materials Science&Engineering University of California San DiegoLa JollaCAUSA

An additional deposition step was added to a multi-step electron beam lithographic fabrication process to unlock the height dimension as an accessible parameter for resonators comprising unit cells of quasi-bound stat... 详细信息

关键词： dimensions dimension intrinsic

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