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IEEE Symposium on Foundations of Computational Intelligence, FOCI

作者： Ryotaro Kamimura Fumihiko Yoshida Yamashita Toshie Ryozo Kitajima Information Technology Center Information Science Laboratory Japan Department of Media Studies Tokai University Hiratsuka Kanagawa Japan Graduate Program in Computer Sciences Tokai University Hiratsuka Kanagawa Japan

In this paper, we propose a new type of information-theoretic approach to variable selection. Many approaches have been proposed in estimating the importance of input variables. The majority of these approaches have focused upon output errors. We here introduce an approach concerning internal representations. First, we delete an input unit with corresponding connection weights. Then, by examining some change in hidden unit activation with and without a input variable, we can extract an important variable. We apply this method to an artificial data in which the number of hidden units is redundantly increased so as to clearly show improved performance and the stability of our method. Then, we apply the method to the cabinet approval ratings in which better interpretation of input variables can be given

关键词： Input variables Neural networks Computational intelligence computer networks Information theory Data mining Standards development Measurement units Information science Laboratories

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Fast time-domain edge-diffraction calculations for interactive acoustic simulations

Eurasip Journal on Advances in Signal Processing

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Eurasip Journal on Advances in Signal Processing 2007年 2007卷

作者： Calamia, Paul T. Svensson, U. Peter Program in Architectural Acoustics School of Architecture Rensselaer Polytechnic Institute Troy NY 12180 United States Department of Computer Science Princeton University Princeton NJ 08544 United States Acoustics Research Centre Department of Electronics and Telecommunications Norwegian University of Science and Technology NO-7491 Trondheim Norway

The inclusion of edge diffraction has long been recognized as an improvement to geometrical-acoustics (GA)modeling techniques, particularly for acoustic simulations of complex environments that are represented as collections of finite-sized planar surfaces. One particular benefit of combining edge diffraction with GA components is that the resulting total sound field is continuous when an acoustic source or receiver crosses a specular-zone or shadow-zone boundary, despite the discontinuity experienced by the associated GA *** interactive acoustic simulations which include only GA components, such discontinuities may be heard as clicks or other undesirable audible artifacts, and thus diffraction calculations are important for high perceptual quality as well as physical realism. While exact diffraction calculations are difficult to compute at interactive rates, approximate calculations are possible and sufficient for situations in which the ultimate goal is a perceptually plausible simulation rather than a numerically exact one. In this paper, we describe an edge-subdivision strategy that allows for fast time-domain edge-diffraction calculations with relatively low error when compared with results from a more numerically accurate solution. The tradeoff between computation time and accuracy can be controlled with a number of parameters, allowing the user to choose the speed that is necessary and the error that is tolerable for a specific modeling scenario.

关键词： Edge detection

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Contributors to the Lab on a Chip cell and tissue engineering in microsystems special issue

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Lab on a Chip 2007年第6期7卷 667-671页

作者： Bhatia, Sangeeta N. Chen, Christoper Bashir, Rashid Beebe, David J. Desai, Tejal Gottwald, Eric Khademhosseini, Ali Langer, Robert S. Piel, Matthieu Takayama, Shuichi Thorsen, Todd Tien, Joe Voldman, Joel Vunjak-Novakovic, Gordana Wu, Mingming Yu, Hanry Massachusetts Institute of Technology Harvard-MIT Division of Health Sciences and Technology Department of Electrical Engineering and Computer Science United States Laboratory for Multiscale Regenerative Technologies United States Department of Innovation University of Pennsylvania Department of Bioengineering United States Cell Biology and Physiology Program Cell Growth and Cancer Program Tissue Microfabrication Laboratory Department of Electrical and Computer Engineering and Biomedical Engineering Purdue University United States Department of Electronics University of Glasgow United Kingdom Department of Physiology and Bioengineering University of California San Francisco CA United States California Institute for Quantitative Biomedical Research UCSF/UC Berkeley Graduate Group in Bioengineering United States Laboratory of Therapeutic Micro and Nanotechnology Institute for Biological Interfaces Germany 3D-Cell Culture Techniques Group Institute for Biological Interfaces Germany Department of Medicine and Health Sciences and Technology Massachusetts Institute of Technology (MIT) United States Institut Curie UMR 144 IC/CNRS France Biomedical Engineering Department University of Michigan United States Department of Biomedical Engineering Macromolecular Science and Engineering Program United States Sibley School of Mechanical and Aerospace Engineering School of Chemical and Molecular Engineering Cornell University United States National University of Singapore Singapore Institute of Bioengineering and Nanotechnology A STAR Singapore

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Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis (vol 69, pg 298, 2007)

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CHEMICAL BIOLOGY & DRUG DESIGN 2007年第6期69卷 455-455页

作者： Chellappan, S. Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Drive Rockville MD 20850 USA Chemical Biology Program Department of Biochemistry and Molecular Pharmacology University of Massachusetts Medical School Worcester MA 01605 USA Department of Biochemistry and Molecular Pharmacology University of Massachusetts Medical School Worcester MA 01605 USA Department of Chemistry Massachusetts Institute of Technology Cambridge MA 02139 USA Biological Engineering Division Department of Electrical Engineering & Computer Science Massachusetts Institute of Technology Cambridge MA 02139 USA *Correspondence: Michael K. Gilson *Correspondence: * Michael K. Gilson gilson@umbi.umd.edu http://gilsonlab.umbi.umd.edu[?][?]These authors contributed equally to this study.

There is a clinical need for HIV protease inhibitors that can evade resistance mutations. One possible approach to designing such inhibitors relies upon the crystallographic observation that the substrates of HIV protease occupy a rather constant region within the binding site. In particular, it has been hypothesized that inhibitors which lie within this region will tend to resist clinically relevant mutations. The present study offers the first prospective evaluation of this hypothesis, via computational design of inhibitors predicted to conform to the substrate envelope, followed by synthesis and evaluation against wild-type and mutant proteases, as well as structural studies of complexes of the designed inhibitors with HIV protease. The results support the utility of the substrate envelope hypothesis as a guide to the design of robust protease inhibitors.

关键词： AIDS crystal drug design inhibitor protease

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An Information Theoretic Framework for Ontology-based Bioinformatics

An Information Theoretic Framework for Ontology-based Bioinf...

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Information Theory and Applications Workshop, ITA

作者： Gil Alterovitz Michael Xiang Marco F. Ramoni Harvard Partners Center for Genetics and Genomics Harvard Medical School Boston MA USA Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge MA USA Department of Biology Massachusetts Institute of Technology Cambridge MA USA Division of Health Sciences and Technology Harvard Medical School and Massachusetts Institute of Technology Boston MA Children's Hospital Informatics Program Boston MA Harvard Partners Center for Genetics and Genomics Harvard Medical School Boston MA.

With myriad information being generated from high-throughput experiments such as microarrays and sequencing technologies, an ever-increasing amount of data is being recorded and analyzed with the help of hierarchical ontologies, such as the gene ontology (GO). We have developed a novel framework- based on the well established foundations of information theory- that allows for the evaluation of new types of hypotheses. The framework, encapsulated in open biomedical ontology-based exploration and search (OBOES), has already been applied in the investigation of different kinds of questions. The resulting framework enables the new field of information theoretic ontology-based analysis. We have applied this framework to create methods to re-engineer ontologies, explore fundamental questions on the evolution of biological complexity, determine optimal ontology terms for bioinformatics analysis, and quantify the usefulness of biofluids as proxies for tissues/diseases. In each case, we found that our methods provide novel, significant findings. An open source Java implementation of OBOES is available at: http://***.

关键词： Ontologies Bioinformatics Genomics Information analysis Biological information theory Information theory Genetic communication Humans Biochemistry Frequency

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Sending the most appropriate feedbacks to students

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WSEAS Transactions on Information science and Applications 2007年第3期4卷 584-591页

作者： Kuo, Rita Hsieh, Athena Chang, Maiga Heh, Jia-Sheng Department of Electronic Engineering Chung-Yuan Christian University No.200 Chung Pei Rd. Chung Li 32023 Taiwan Dep. of Information and Computer Engineering Chung-Yuan Christian University No.200 Chung Pei Rd. Chung Li 32023 Taiwan National Science and Technology Program for e-Learning in Taiwan No.300 Jungda-Rd. Chung-Li 32001 Taiwan

It is important for students getting suitable feedback information when either they are doing or completing a learning activity. This research tries to know what kind of feedback message is really useful to students. For this purpose, this paper develops a workable e-learning environment with feedback mechanism to gather the learning effects of students with different kinds of feedbacks. The experiment involves five fifth-grade classes and divides five classes into three different groups. The students in the control group have no feedback and students in the other two groups have different kinds of feedback messages. The analysis of experiment data contains two parts: the first one evaluates the feedback efficiencies for all groups;and, then all students will be separated into three clusters based on their academic achievement in order to do further analysis.

关键词： Feedback

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Waters network's potential to transform environmental engineering education

Waters network's potential to transform environmental engine...

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114th Annual ASEE Conference and Exposition, 2007

作者： Eschenbach, Elizabeth Montgomery, Jami Johnson, James Brus, Chris Carlson, Patricia Giammar, Dan Grauer, Bette Hotaling, Liesl Oguntimein, Gbekeloluwa Safferman, Steven Wentling, Tim Humboldt State University United States Department of Environmental Resources Engineering Humboldt State University United States WATERS Network - CLEANER Project Office Network Howard University United States Department of Environmental Engineering College of Engineering Architecture and Computer Sciences Howard University United States American Academy of Environmental Engineers United States University of Iowa United States Program University of Iowa United States Rose-Hulman Institute of Technology United States Department of Rhetoric Rose-Hulman Institute of Technology United States National Research Council U. S. Air Force United States NASA's Classroom of the Future Wheeling WV United States Washington University United States Department of Energy Environmental and Chemical Engineering Washington University St. Louis United States Environmental Studies Program Center for Materials Innovation United States McPherson High School United States McPherson High School McPherson KS United States Stevens Institute of Technology United States Stevens Institute of Technology United States Morgan State University United States Michigan State University United States Biosystems and Agricultural Engineering Department Michigan State University United States University of Dayton United States Education Planning Committee National Center for Supercomputing Applications United States Department of Information Science Graduate School of Library and Information Science National Center for Supercomputing Applications University or Illinois United States Knowledge and Learning Systems Group NCSA United States

The WATERS Network (WATer and Environmental Research Systems Network) will be an integrated real-time distributed observing system which will enable academic and government scientists, engineers, educators, and practitioners to advance effective management of our nation's water resources by understanding human interactions with water and the natural and built environment. WATERS will provide easily accessible real time environmental data as well as analysis tools to engineers, scientists, educators, K- graduate students and policymakers so they can better understand how water quantity, quality and related components of the hydrologic cycle are impacted by natural and human influences. The WATERS strategic plan will be completed by July 2007 and requires constituent input. This paper describes the draft Conceptual Design and the Education Plan of WATERS Network. This paper will highlight the potential impact of WATERS on undergraduate and graduate environmental engineering education in order to elicit input from the environmental engineering education community on how WATERS Network could better meet the future needs of undergraduate and graduate students and educators. More information can be found at ***. © American Society for Engineering Education, 2007.

关键词： Water resources

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MODELING AND CONTROL OF ELEVATORS BY STATECHARTS

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Asian Journal of Control 2008年第2期6卷

作者： Yi-Sheng Huang Sheng-Luen Chung Mu-Der Jeng Department of Aeronautical Engineering Chung Cheng Institute of Technology National Defense University Tashi Taoyuan 335 Taiwan R.O.C. Department of Electrical Engineering National Taiwan University of Science and Technology Taipei 106 Taiwan R.O.C. Department of Electrical Engineering National Taiwan Ocean University Kellung 202 Taiwan R.O.C. MuDer Jeng received the Ph.D. degree in computer and systems engineering from Rensselaer Polytechnic Institute Troy NY in 1992. Since August 1992 Dr. Jeng has been with National Taiwan Ocean University Keelung Taiwan where he is currently a full Professor at the Department of Electrical Engineering. His current research interests include Petri nets discrete event systems computer integrated manufacturing semiconductor factory automation embedded systems. Dr. Jeng is the author/co-author of over 120 book chapters journal papers and conference papers. Dr. Jeng received the Franklin V. Taylor Outstanding Paper Award from the IEEE Systems Man and Cybernetics Society in 1993. He was granted the Research Award by the National Science Council of Taiwan annually from 1994 to 2000. He is an Associate Editor for IEEE Transactions on Systems Man and Cybernetics-Part A IEEE Transactions on Robotics and Automation IEEE Transactions on Robotics and serves on the Editorial Board of International Journal of Computer Integrated Manufacturing. He has been a Guest Editor for eight leading journals. Dr. Jeng is the Chair of the Technical Committee on Discrete Event Systems of the IEEE SMC Society and the Founding Chair of the Technical Committee on Semiconductor Factory Automation of the IEEE Robotics and Automation Society. He served as the Exhibitions Chair of 2003 IEEE International Conference on Robotics and Automation and the Special Sessions Chair of 2004 IEEE International Conference on Networking Sensing and Control. He serves as a Program Co-Chair of 2005 IEEE International Conference on Networking Sensing and Control and the Organization Commit

Statechart has been utilized as a visual formalism for the modeling of complex and interactive systems for its illuminating features on describing properties of causality, concurrency, and synchronization. This paper presents the application of satechart to the modeling, design and implementation of an elevator system, whose system behavior involves aggregating complexity of state descriptions, and imposition of underlying control policy. Based on the operational flow of an elevator, we derive the associated statechart model by looking into the inherent hierarchical structure of the elevator. The advantage of the proposed approach is the clear presentation of system behavior in terms of conditions and events that cause the transitions in system dynamics. Implementation of the controlled elevator based on the modeled statechart is also presented.

关键词： Statechart interactive systems elevator

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Apriori data mining on rotationally invariant multiresolutional moments for pattern recognition

Apriori data mining on rotationally invariant multiresolutio...

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9th Joint Conference on Information sciences, JCIS 2006

作者： Rodtook, A. Makhanov, S.S. Department of Computer Science Ramkhamhaeng University Thailand Information Technology and Computer Program Sirindhorn International Institute of Technology Thammasat University Thailand

ISBN: (纸本)9078677015

We propose a new feature selection procedure based on a combination of a pruning algorithm, Apriori mining techniques and fuzzy C-mean clustering. The feature selection algorithm is designed to mine on a multiresolution filter bank composed of rotationally invariant moments. The numerical experiments, with more than 10,000 images, demonstrate an accuracy increase of about 5% for a low noise, 15% for an average noise and 20% for a high-level noise.

关键词： Data mining

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A treasure hunting learning model for students studying history and culture in the field with cellphone

A treasure hunting learning model for students studying hist...

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6th International Conference on Advanced Learning Technologies, ICALT 2006

作者： Chang, Alex Chang, Maiga Hsieh, Athena Department of Information and Computer Engineering Chung-Yuan Christian University National Science and Technology Program for E-learning Taiwan

ISBN: (纸本)0769526322

In the treasure hunting process, the hunters could only get few hints with simple words, therefore they must think over with the experience they learned before. The goal of this paper is to propose a treasure hunting learning model and implement a system based on the model. Within the treasure hunting learning model students will become a treasure hunter when they are learning in the field. The learning model makes learning more fun by asking students some questions according to their learning records and physical position. In order to make the system portable and treasure hunting liked, we implement the treasure hunting learning model with the most simple and common cellphone, that is the text-mode cellphone. To verify the learning model is working, a traditional history and culture course in college was taken as the experiment. © 2006 IEEE.

关键词： Learning systems

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