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International Conference on Informatics, Multimedia, Cyber and Information System (ICIMCIS)

作者： Alam Ahmad Hidayat Rudi Nirwantono Mahmud Isnan Joko Pebrianto Trinugroho Bens Pardamean Mathematics Department School of Computer Science Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Biotechnology Department Faculty of Engineering Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Computer Science Department Bioinformatics and Data Science Research Center BINUS Graduate Program Jakarta Indonesia

Understanding the mechanistic interpretability of mutation effects in a protein can help predict the clinical implications of the genetic variants. Hence, computational variant effect predictions that involve protein structural features of the protein mutations might be suitable in this case. In this work, we focus on BRCT domains of BRCA1 gene that is widely studied in breast cancer studies. We retrieved 88 selected missense variants found in BRCT domains annotated in both ClinVar and gnomAD databases. To computationally characterize the pathogenic property of the mutations we used two types of features extracted from protein structures: a change in free Gibbs energy and a set of features derived from molecular dynamics simulations of each mutant. Using a dimensional reduction and Gaussian mixture model (GMM)-based clustering we demonstrate that the variants are segregated into two regions that may correspond to their pathogenic status. This method can be a potential computational pipeline for providing the preliminary mechanistic interpretation of mutation effects in terms of their thermodynamic and structural features.

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Implementation and Evaluation of 0.6 µm CMOS Complex RCPF for Accurate Frequency Response Measurement

IEEJ Transactions on Electronics, Information and Systems

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IEEJ Transactions on Electronics, Information and Systems 2025年第1期145卷 25-37页

作者： Sato, Lina Fukagawa, Kanta Shouno, Kazuhiro Tanimoto, Hiroshi Muto, Cosy Moriyama, Seijiro Takahashi, Chikau Yoshino, Michitaka Graduate School of Science and Technology Degree Programs in Systems and Information Engineering Master’s Program in Computer Science University of Tsukuba Japan Division of Information Engineering University of Tsukuba 1-1-1 Tennoudai Ibaraki Tsukuba305-8573 Japan Kitami Institute of Technology 165 Koen-cho Hokkaido Kitami090-8507 Japan Faculty of Education Nagasaki University 1-14 Bunkyo-machi Nagasaki852-8521 Japan Anagix Corporation 3-22-27 Numama Kanagawa Zushi249-0004 Japan Takamori Corporation Japan Research Center for Micro-Nano Technology Hosei University 3-11-15 Midori-cho Koganei Tokyo184-0003 Japan

This paper describes the implementation and evaluation of an RC polyphase filter (RCPF) and circuitry for measuring its frequency characteristics. The integrated circuit is fabricated on a 0.6 µm CMOS process and its supply voltage is 5 V. The integrated circuit includes a filter under test (FUT), a four-phase square wave generator, several analog switches and differential amplifiers to amplify the high-impedance signals of the RCPF. This FUT is a third-order complex RCPF whose passband is 8 − 40 MHz. This paper describes the design of these circuits in detail. This integrated circuit can select two measurement methods by means of external control signals. The first method uses a four-phase square wave. The frequency characteristics are measured by using an on-chip four-phase square wave generator driven by an external clock generator and by a spectrum analyzer tuned to the fundamental frequency. The second method uses an external network analyzer. Furthermore, this integrated circuit is equipped with a calibration circuit to measure the frequency characteristics of the circuitry except FUT by passing through the input / output signals of the FUT. As a result, the frequency characteristics of the FUT itself can be accurately measured. The effectiveness is confirmed through evaluation of the fabricated integrated circuit. © 2025 The Institute of Electrical Engineers of Japan.

关键词： Differential amplifiers

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Local Periodicity-Based Beat Tracking for Expressive Classical Piano Music

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IEEE/ACM Transactions on Audio Speech and Language Processing 2023年 31卷 2824-2835页

作者： Chiu, Ching-Yu Muller, Meinard Davies, Matthew E. P. Su, Alvin Wen-Yu Yang, Yi-Hsuan National Cheng Kung University Academia Sinica Graduate Program of Multimedia Systems and Intelligent Computing Tainan701401 Taiwan International Audio Laboratories Erlangen Erlangen91058 Germany University of Coimbra Department of Informatics Engineering Centre for Informatics and Systems Coimbra3004-531 Portugal National Cheng Kung University Department of Computer Science and Information Engineering Tainan701401 Taiwan Taiwan AI Labs Yating Music Team Taipei103622 Taiwan Academia Sinica Research Center for IT Innovation Taipei11529 Taiwan

To model the periodicity of beats, state-of-the-art beat tracking systems use 'post-processing trackers' (PPTs) that rely on several empirically determined global assumptions for tempo transition, which work well for music with a steady tempo. For expressive classical music, however, these assumptions can be too rigid. With two large datasets of Western classical piano music, namely the Aligned Scores and Performances (ASAP) dataset and a dataset of Chopin's Mazurkas (Maz-5), we report on experiments showing the failure of existing PPTs to cope with local tempo changes, thus calling for new methods. In this paper, we propose a new local periodicity-based PPT, called predominant local pulse-based dynamic programming (PLPDP) tracking, that allows for more flexible tempo transitions. Specifically, the new PPT incorporates a method called 'predominant local pulses' (PLP) in combination with a dynamic programming (DP) component to jointly consider the locally detected periodicity and beat activation strength at each time instant. Accordingly, PLPDP accounts for the local periodicity, rather than relying on a global tempo assumption. Compared to existing PPTs, PLPDP particularly enhances the recall values at the cost of a lower precision, resulting in an overall improvement of F1-score for beat tracking in ASAP (from 0.473 to 0.493) and Maz-5 (from 0.595 to 0.838). © 2014 IEEE.

关键词： Hidden Markov models

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High Spatial Resolution Terahertz Time-Domain Imaging of Murine Pancreatic Ductal Adenocarcinoma Tissues

High Spatial Resolution Terahertz Time-Domain Imaging of Mur...

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2023 Conference on Lasers and Electro-Optics, CLEO 2023

作者： Chakraborty, Debamitra Mills, Bradley N. Cheng, Jing Komissarov, Ivan Gerber, Scott Sobolewski, Roman Materials Science Graduate Program University of Rochester RochesterNY14627-1299 United States Laboratory for Laser Energetics University of Rochester RochesterNY14623 United States Department of Surgery University of Rochester Medical Center RochesterNY14642 United States Department of Electrical and Computer Engineering University of Rochester RochesterNY14627-0231 United States

We developed a terahertz time-domain spectroscopy system to generate high-resolution 2-dimensional images of paraffin-embedded murine pancreatic ductal adenocarcinoma tissues using the refractive index and absorption ... 详细信息

ISBN: (纸本)9781957171258

关键词： Tissue

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Assessing Media’s Representation of Frustration Towards Venezuelan Migrants in Colombia 16th

Assessing Media’s Representation of Frustration Towards Ven...

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16th International Conference on Social Computing, Behavioral-Cultural Modeling and Prediction and Behavior Representation in Modeling and Simulation, SBP-BRiMS 2023

作者： Llinas, Brian Huseynli, Guljannat Frydenlund, Erika Palacio, Katherine Llinas, Humberto Padilla, Jose J. Computer Science Department Old Dominion University NorfolkVA United States Graduate Program of International Studies Old Dominion University NorfolkVA United States Virginia Modeling Analysis and Simulation Center Old Dominion University SuffolkVA United States Universidad del Norte Kilómetro 5 Vía Atlántico Puerto Colombia Colombia

ISBN: (纸本)9783031431289

This research utilizes statistical path modeling to examine the relationship between the number of Venezuelans migrating to Colombia due to economic collapse and the media's coverage of specific topics. We focus on media coverage expressing frustration regarding migration, infrastructure, government, and geopolitics. Our approach combines quantitative analysis of code frequencies from qualitative content analysis of 1,360 regional newspaper articles on migration-related issues. Our findings indicate that an increase in the Venezuelan population in Colombia leads to more negative media coverage of infrastructure impacts, such as hospitals and schools. This negative coverage, referred to as "frustration," indirectly contributes to increased coverage of infrastructure frustration. This suggests an opportunity for intervention by balancing media coverage to reduce the excessive use of negative language and stereotypes, potentially mitigating anti-migrant sentiment fueled by frustration towards infrastructure. Furthermore, we observe that as migration increases, coverage of frustration towards geopolitics decreases, while frustration towards the Colombian government rises. This shift may reflect a transition from contemplating the causes of migration to focusing on the humanitarian response (or lack thereof) by the host government in accommodating the new arrivals. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

关键词： Artificial intelligence

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Implementation of expert systems in potassium deficiency in cocoa plants using forward chaining method 7

Implementation of expert systems in potassium deficiency in ...

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7th International Conference on computer science and Computational Intelligence, CSCI 2022

作者： Hafizal, Muhammad Titan Putra, Dian Pratama Wirianata, Herry Nugraha, Nanda Satya Suparyanto, Teddy Hidayat, Alam Ahmad Pardamean, Bens Faculty of Agriculture STIPER Institute of Agriculture Yogyakarta55282 Indonesia Faculty of Forestry STIPER Institute of Agriculture Yogyakarta55282 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta11480 Indonesia

As one of the largest exporters in the world, cocoa (Theobroma cacao L.) production in Indonesia provides an important contribution to the plantation sector that can, directly and indirectly, attribute to the national economic development. However, recent data shows a decline in cocoa productivity in Indonesia. This is arguably caused by various factors, including poor agricultural management and practices in cocoa plantations, that may lead to lower fertility in the soil and an increased risk of diseases and pests. Potassium deficiency is a major contributing factor to the low soil fertility that affects cocoa yields. Therefore, in this work, we implement an application with an expert system utilizing the forward chaining method to detect potassium deficiency in cocoa plants and then give a fertilization-based recommendation based on the plants' condition. The system employs a set of rules to identify symptoms related to the deficiency on the sample photo of a cocoa leaf according to the channels of red, green, and blue of the image. The sample images of cocoa leaves are submitted to the application with an easy-To-use interface that can show the scanning result and proceed to display the suggested quantity of fertilizers to prevent potassium deficiency. Implementing the system can contribute constructive impacts to improve current practices in the overall cropping system of cocoa plants. © 2022 Elsevier B.V.. All rights reserved.

关键词： Expert systems

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Slice-Fusion: Reducing False Positives in Liver Tumor Detection for Mask R-CNN

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IEEE/ACM Transactions on Computational Biology and Bioinformatics 2023年第5期20卷 3267-3277页

作者： Tu, Deng-Yao Lin, Peng-Chan Chou, Hsin-Hung Shen, Meng-Ru Hsieh, Sun-Yuan National Cheng Kung University Master Degree Program on Artificial Intelligence Tainan City70101 Taiwan National Cheng Kung University Institute of Medical Informatics Department of Oncology Department of Genomic Medicine National Cheng Kung University Hospital College of Medicine Department of Computer Science and Information Engineering Tainan City70101 Taiwan National Chi Nan University Department of Computer Science and Information Engineering Nantou County54561 Taiwan National Cheng Kung University Graduate Institute of Clinical Medicine Department of Obstetrics and Gynecology Department of Pharmacology National Cheng Kung University Hospital College of Medicine Tainan City70101 Taiwan National Cheng Kung University Institute of Medical Information Institute of Manufacturing Information and Systems Center for Innovative FinTech Business Models International Center for the Scientific Development of Shrimp Aquaculture Department of Computer Science and Information Engineering Tainan City70101 Taiwan

Automatic liver tumor detection from computed tomography (CT) makes clinical examinations more accurate. However, deep learning-based detection algorithms are characterized by high sensitivity and low precision, which hinders diagnosis given that false-positive tumors must first be identified and excluded. These false positives arise because detection models incorrectly identify partial volume artifacts as lesions, which in turn stems from the inability to learn the perihepatic structure from a global perspective. To overcome this limitation, we propose a novel slice-fusion method in which mining the global structural relationship between the tissues in the target CT slices and fusing the features of adjacent slices according to the importance of the tissues. Furthermore, we design a new network based on our slice-fusion method and Mask R-CNN detection model, called Pinpoint-Net. We evaluated proposed model on the Liver Tumor Segmentation Challenge (LiTS) dataset and our liver metastases dataset. Experiments demonstrated that our slice-fusion method not only enhance tumor detection ability via reducing the number of false-positive tumors smaller than 10mm, but also improve segmentation performance. Without bells and whistles, a single Pinpoint-Net showed outstanding performance in liver tumor detection and segmentation on LiTS test dataset compared with other state-of-the-art models. © 2004-2012 IEEE.

关键词： Tumors

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Twitter-based text classification using svm for weather information system 6

Twitter-based text classification using svm for weather info...

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6th International Conference on Information Management and Technology, ICIMTech 2021

作者： Purwandari, Kartika Rahutomo, Reza Sigalingging, Join W. C. Ajy Kusuma, Mahisa Prasetyo, Aji Pardamean, Bens Research Center Bina Nusantara University Bioinformatics and Data Science Jakarta11480 Indonesia BMKG Meteorological Climatological and Geophysical Agency Database Center Division Jakarta10720 Indonesia Bina Nusantara University BINUS Graduate Program - Master of Computer Science Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9781665449373

The popularity of social media amplified the amount of text data that is used to enrich text classification research with machine learning approach. The modernization in weather information system is needed to produce real-time weather information using the involvement of Twitter users. GetOldTweets was used to cover data acquisition from Twitter. Support Vector Machine (SVM) was deployed as a machine learning model for text classification. The result was delivered in Esri Maps features. It facilitated a social sensing for Indonesia weather information system by using Twitter posts from Indonesian users with 93% accuracy. © 2021 IEEE.

关键词： Data acquisition

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Electronic-photonic quantum systems on-chip

Electronic-photonic quantum systems on-chip

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Quantum 2.0, QUANTUM 2022

作者： Wang, Imbert Ramesh, Anirudh Kramnik, Danielius Fargas Cabanillas, Josep M. Stojanović, Vladimir Kumar, Prem Popović, Miloš A. Department of Electrical and Computer Engineering Photonics Center Boston University BostonMA02215 United States Graduate Program in Applied Physics Northwestern University EvanstonIL60208 United States Department of Electrical Engineering and Computer Science UC Berkeley BerkeleyCA94720 United States Center for Photonic Communication and Computing Dept. of Electrical and Computer Eng. Northwestern University EvanstonIL60208 United States

We present progress towards realizing electronic-photonic quantum systems on-chip;particularly, entangled photon-pair sources, placing them in the context of previous work, and outlining our vision for mass-producible... 详细信息

ISBN: (纸本)9781957171111

关键词： Quantum entanglement

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Towards Emotionally Intelligent Software Engineers: Understanding Students’ Self-Perceptions After a Cooperative Learning Experience

arXiv

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arXiv 2025年

作者： Araújo, Allysson Allex Kalinowski, Marcos Paixao, Matheus Graziotin, Daniel Center for Science and Technology Federal University of Cariri Juazeiro do Norte Brazil Department of Informatics Pontifical Catholic University of Rio de Janeiro Rio de Janeiro Brazil Graduate Program in Computer Science State University of Ceará Fortaleza Brazil University of Hohenheim Stuttgart Germany

[Background] Emotional Intelligence (EI) can impact Software Engineering (SE) outcomes through improved team communication, conflict resolution, and stress management. SE workers face increasing pressure to develop both technical and interpersonal skills, as modern software development emphasizes collaborative work and complex team interactions. Despite EI’s documented importance in professional practice, SE education continues to prioritize technical knowledge over emotional and social competencies. [Objective] This paper analyzes SE students’ self-perceptions of their EI after a two-month cooperative learning project, using Mayer and Salovey’s four-ability model to examine how students handle emotions in collaborative development. [Method] We conducted a case study with 29 SE students organized into four squads within a project-based learning course, collecting data through questionnaires and focus groups that included brainwriting and sharing circles, then analyzing the data using descriptive statistics and open coding. [Results] Students demonstrated stronger abilities in managing their own emotions compared to interpreting others’ emotional states. Despite limited formal EI training, they developed informal strategies for emotional management, including structured planning and peer support networks, which they connected to improved productivity and conflict resolution. [Conclusion] This study shows how SE students perceive EI in a collaborative learning context and provides evidence-based insights into the important role of emotional competencies in SE education. Copyright © 2025, The Authors. All rights reserved.

关键词： Students

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