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2006 8th International Conference on Solid-State and Integrated Circuit Technology

作者： Mansun Chan Chi-Kong Yeung Yijin Wang Jin He Sven Ingebrandt Andreas Offenhaeusser Dept.of Electronic and Computer Engineering Hong Kong University of Science & Technology Bioengineering Graduate Program Hong Kong University of Science & Technology Institute of Microelectronic Peking University Juelich Research Center Institute for Thin Films and Interfaces(ISG-2)Leo-Brandt Str.52425 JuelichGermany

ISBN: (纸本)1424401607

This paper describes the development of a Multi-Electrode Array(MEA)with Guided Network for Cell-to-Cell Communication Transduction using a standard integrated circuit(IC) fabrication *** conventional electronic system,bio-system requires a special handling environment that is uncommon in conventional IC *** work presented here demonstrated the interaction between electrically active cells such as neuron and cardiac cells and an IC based *** a carefully designed array,and ionic action of a cell, extracellular signals can be captured and imaged.

关键词： Capturing Cellular Communication with Guided Electrode Network on a Silicon Integrated Circuit Chip

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Identifying interaction sites in "Recalcitrant" proteins: Predicted protein and RNA binding sites in REV proteins of HIV-1 and EIAV agree with experimental data

Identifying interaction sites in "Recalcitrant" proteins: Pr...

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11th Pacific Symposium on Biocomputing 2006, PSB 2006

作者： Terribllini, Michael Lee, Jae-Hyung Yan, Changhui Jernigan, Robert L. Carpenter, Susan Honavar, Vasant Dobbs, Drena Bioinformatics and Computational Biology Graduate Program LH. Baker Center for Bioinformatics and Biological Statistics Iowa State University Ames IA 50010 United States Department of Computer Science Iowa State University Ames IA 50010 United States Department of Biochemistry Biophysics and Molecular Biology Iowa State University Ames IA 50010 United States Department of Genetics Development and Cell Biology Iowa State University Ames IA 50010 United States Artificial Intelligence Research Laboratory Center for Computational Intelligence Learning and Discovery Iowa State University Ames IA 50010 United States Department of Veterinary Microbiology and Pathology Washington State University Pullman WA. 99164 United States

ISBN: (纸本)9812564632

Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation or gene expression, protein synthesis, and replication and assembly of many viruses. We have developed machine learning approaches for predicting which amino acids of a protein participate in its interactions with other proteins and/or nucleic acids, using only the proiein sequence as input. In this paper, we describe an application of classifiers trained on datasets of well-characterized protein-protein and protein-RNA complexes for which experimental structures are available. We apply these classifiers to the problem of predicting protein and RNA binding sites in the sequence of a clinically important protein for which the structure is not known: the regulatory protein Rev, essential for the replication of HIV-I and other lentiviruses. We compare our predictions with published biochemical, genetic and partial structural information for HIV-1 and EIAV Rev and with our own published experimental mapping of RNA binding sites in EIAV Rev. The predicted and experimentally determined binding sites are in very good agreement. The ability to predict reliably the residues of a protein that directly contribute to specific binding events - without the requirement for structural information regarding either the protein or complexes in which it participates - can potentially generate new disease intervention strategies.

关键词： Binding sites

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Real-time organ motion tracking and fast image registration system for MRI-guided surgery

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Systems and computers in Japan 2006年第1期37卷 83-92页

作者： Tokuda, Junichi Hirano, Masaya Tsukamoto, Tetsuji Dohi, Takeyoshi Hata, Nobuhiko Graduate School of Information Science and Technology University of Tokyo Tokyo 113-8656 Japan GE Yokogawa Medical Systems Ltd. Hino 191-8503 Japan International Society for Computer-Aided Surgery Japan Society for Computer-Aided Surgery Japan Society for Magnetic Resonance in Medicine GE Yokogawa Medical Systems Ltd. Imaging Application Tech. Center MR Group R and D Laboratory Technology Center GE Yokogawa Medical Systems Ltd. Society for Magnetic Resonance in Medicine Graduate School of Information Science and Technology Society for Life Support Technology Japan Society for Organ Preservation Biology and Medicine Society for Precision Engineering Society for Medical Image Computing and Computer Assisted Intervention International Union for Physics and Engineering Sciences in Medicine JSMEBE Japan Society for Life Assistance Technology Brigham and Women's Hospital Harvard Medical School MR Therapy Program

The advantage of magnetic resonance imaging (MRI)-guided surgery, in which MR images taken during surgery are used to guide the surgery, has been recognized recently. However, there is a problem, due to long imaging time of MRI, that it is difficult to capture the respiratory organ motion. It is often a constraint that the patient must hold his or her breath, especially in the treatment of the abdominal region. Consequently, this paper proposes a method of eliminating this constraint in MRI-guided surgery by real-time monitoring of the movement of the organ involved in the surgery by means of the signal derived from MRI. Specifically, the navigator echo is extracted in imaging during surgery. The movement of the organ involved in surgery is detected on the basis of the change in the calculated projection profile, and the results are presented to the surgeon. In this study, the procedure is built into a 1.5-T clinical MRI system. The feasibility of the proposed system was examined under clinical conditions by evaluating its accuracy and delay in a phantom experiment, and also in an in vivo experiment on the liver of a volunteer. The results are reported in this paper. © 2005 Wiley Periodicals, Inc.

关键词： Motion estimation

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Transforming K-12 education via the collaborative large-scale engineering analysis network for environmental research (CLEANER) project

Transforming K-12 education via the collaborative large-scal...

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113th Annual ASEE Conference and Exposition, 2006

作者： Eschenbach, Elizabeth Johnson, James H. Brus, Chris Carlson, Patricia Giammar, Dan Grauer, Bette Hotaling, Liesl Oguntimein, Gbekeloluwa Safferman, Steven Wentling, Tim Humboldt State University United States Department of Environmental Resources Engineering Humboldt State University United States Howard University United States Department of Environmental Engineering College of Engineering Architecture and Computer Sciences Howard University United States Board of Scientific Counselors Executive Committee U.S. Environmental Protection Agency Office of Research and Development United States EPA's Science Advisory Board Department of Energy-sponsored HBCU/MI Environmental Technology Consortium Board Environmental Studies and Toxicology and the Engineering Council of the American Society for Engineering Education United States University of Iowa United States Program University of Iowa United States Rose-Hulman Institute of Technology United States Department of Rhetoric Rose-Hulman Institute ot Technology U.S. Air Forcer United States Army's Aberdeen Proving Ground NASA's Classroom of the Future Wheeling WV United States Washington University United States Department of Civil Engineering Washington University St. Louis United States Environmental Engineering Science Program Center for Materials Innovation United States McPherson High School United States McPherson High School McPherson KS United States Stevens Institute of Technology United States Stevens Institute of Technology United States Morgan State University United States Michigan State University United States Biosystems and Agricultural Engineering Department Michigan State University United States University of Dayton United States U.S. EPA Office of Research and Development United States National Center for Supercomputing Applications United States Department of Information Science Graduate School of Library and Information Science National Center for Supercomputing Applications University of Illinois United States

The Collaborative Large-scale Engineering Analysis Network for Environmental Research (CLEANER) Project Office has been established with funding from the National science Foundation (NSF) to the University of Illinois Urbana-Champaign (UIUC) and a coalition of 11 other institutions. The project office is coordinating the creation of a strategic plan consisting of research, cyberinfrastructure, and education plans that set forth a roadmap for the collaborative engineering analysis network for the study of environmental problems. This report will be completed by July 2007 and requires input from K-12 educators, administrators and other stakeholders in K-12 education. This paper describes the CLEANER project, provides an example of the CLEANER Education Committee's vision for the K-12 area and lists contacts for further information. The intention of this paper is to elicit input from the K-12 engineering education community, including K-12 educators, on how the CLEANER Education Plan could better meet the future needs of K-12 students and educators © American Society for Engineering Education, 2006.

关键词： Engineering education

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A proposal for blind FIR equalization of time-varying channels

A proposal for blind FIR equalization of time-varying channe...

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2005 IEEE Workshop on Machine Learning for Signal Processing

作者： Junqueira, Cynthia De França, Fabrída O. Attux, Romis R. F. Suyama, Ricardo De Castro, Leandro N. Von Zuben, Fernando J. Romano, João Marcos T. Institute of Aeronautics and Space Aerospace Technical Center Brazil DSPCom FEEC Unicamp Brazil LBiC FEEC Unicamp Brazil Graduate Program in Computer Science UniSantos Brazil

ISBN: (纸本)0780395174

The multimodal and time-varying aspects of blind equalization problems in communication systems are treated here by means of an immune-inspired strategy capable of estimating the coefficients of the FIR equalization filter in an unsupervised manner. The associated optimization problem is solved by means of a population-based search technique characterized by a dynamic control of the population size and diversity maintenance. Static and time-varying channels have been proposed in simulated scenarios, aiming at indicating the tracking capability derived from the adaptive adjustment of the coefficients of the blind equalizer. © 2005 IEEE.

关键词： Time varying networks

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Stepped-frequency LFM trains with low range sidelobes

Stepped-frequency LFM trains with low range sidelobes

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International Radar Symposium, IRS 2005

作者： Chebanov, Dmitry Gladkova, Irina Ph.D. Program in Computer Science Graduate Center City University of New York 365 Fifth Avenue New YorkNY United States Computer Science Department City College of New York 138th Street and Convent Avenue New YorkNY United States

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On epistemic logic with justification

On epistemic logic with justification

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Tenth Conference on the Theoretical Aspects of Rationality and Knowledge, TARK 2005

作者： Artemov, Sergei Nogina, Elena Graduate Center CUNY Ph.D. Program in Computer Science 365 Fifth Avenue New York NY 10016 United States BMCC CUNY Department of Mathematics 199 Chambers Street New York NY 10007 United States

ISBN: (纸本)9810534124

The true belief components of Plato's tripartite definition of knowledge as justified true belief are represented in formal epistemology by modal logic and its possible worlds semantics. At the same time, the justification component of Plato's definition did not have a formal representation. This paper introduces the notion of justification into formal epistemology. Epistemic logic with justification, along with the usual knowledge operator F (F is known), contains assertions t:F (t is a justification for F). We suggest an epistemic semantics which augments Kripke models with a natural Fitting-style treatment of justification assertions t:F. Completeness and some new specific properties of basic systems of epistemic logic with justification are established.

关键词： Knowledge acquisition

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A Proposal for Blind Fir Equalization of Time-Varying Channels

A Proposal for Blind Fir Equalization of Time-Varying Channe...

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IEEE Workshop on Machine Learning for Signal Processing

作者： C. Junqueira F.O. de Franca R.R.F. Attux R. Suyama L.N. de Castro F.J. von Zuben J.M.T. Romano DSPCom Unicamp Brazil Institute of Aeronautics and Spacel Aerospace Technical Center Brazil LBiC/DCA/FEEC/Unicamp Brazil LBiC Unicamp Brazil DSPCom/FEEC/Unicamp Brazil Graduate Program in Computer Science UniSantos Brazil

关键词： Proposals Finite impulse response filter Blind equalizers Time-varying channels Time varying systems computer science Aerodynamics Size control Communication system control High performance computing

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Journal of Information science and Engineering: Editorial notice

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Journal of Information science and Engineering 2005年第5期21卷 i-ii页

作者： Lee, Der-Tsai Amato, Nancy M. Chang, Shih-Fu Chen, Homer H. Chen, Tsuhan Hsu, Tsan-Sheng Hwang, Jenq-Neng Kuo, Sy-Yen Kuo, Tei-Wei Li, Chung-Sheng Tokuyama, Takeshi Wing, Jeannette Wu, Tzong-Chen Yen, John Computer Science at Texas A and M University United States Parasol Laboratory United States IEEE Transactions on Parallel and Distributed Systems Computing Research Association's Committee on the Status of Women in Computing Research CRA-W's Distributed Mentor Program United States Department of Electrical Engineering Columbia University United States Lab. United States College of Electrical Engineering and Computer Science National Taiwan University Taiwan IEEE Transactions on Circuits and Systems for Video Technology IEEE Department of Electrical and Computer Engineering Carnegie Mellon University Pittsburgh PA United States ACM ACM SIGACT IEEE Computer Society IICM Austria Research and Development of the Department Multimedia Signal Processing Technical Committee IEEE Signal Processing Society United States IEEE Transactions on Circuits and systems for Video Technology College of Electrical Engineering and Computer Science National Taiwan Ocean University Keelung Taiwan Department of Electrical Engineering National Taiwan University Taiwan Department of Computer Science and Information Engineering National Taiwan University Taipei Taiwan IEEE Technical Committee on Real-Time Systems Computer Science Division IBM T.J. Watson Research Center United States IBM Research Division Graduate School of Information Sciences Tohoku University Japan ACM IPSJ Mathematical Society of Japan Japan Department of Computer Science Computer Science Department Carnegie Mellon University United States National Academies of Science's Computer Science and Telecommunications Board United States Microsoft's Trustworthy Academic Advisory Board Intel Research Pittsburgh's Advisory Board United States Dartmouth's Institute for Security Technology Studies Advisory Committee Canada Sloan Research Fellowships Program Committee United States ACM Taiwan China Information Sciences and Technology Pennsylvania State University United States Laboratory for Intelligent Agents Penn State's School of Info

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A segmentation-based automatic navigation technique for virtual endoscopy

A segmentation-based automatic navigation technique for virt...

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2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

作者： Carvalho, Bruno M. Herman, Gabor T. Dept. of Comp. and Info. Science University of Pennsylvania Doctoral Program in Computer Science Graduate Center City University of New York

ISBN: (纸本)0780383885

Virtual endoscopy (VE) mimics the examination consisting of introducing an endoscope into a tubular structure for diagnostic purposes. One of the main problems in VE is the computattion of the navigation path that the virtual camera will travel while producing the animation that will be viewed by the specialist. We propose a technique that allows the automatic computation of navigation paths connecting a starting and one or more end points inside the structure to be visualized. The computation of the path uses the connectedness map produced by the segmentation algorithm that has been used to identify the structure to be visualized in the image. A simple smoothing operation is then applied to this path to produce the final navigation path. © 2004 IEEE.

关键词： Endoscopy

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