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Mapping Multiple Wild Pig Species’ Population Dynamics in Southeast Asia During the African Swine Fever Outbreak (2018–2024)

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Conservation Letters 2025年第3期18卷

作者： Zoë E. Lieb Erik Meijaard Jedediah F. Brodie Adi Shabrani Jayasilan Mohd-Azlan Jatna Supriatna Matthew John Struebig Nicolas J. Deere Katie L. Spencer Suipeng Heon Lok-Jinn Wong Suzika Juiling Andrew Hearn Camille N. Z. Coudrat Agus Sudibyo Jati Matthew Linkie Dusit Ngoprasert Dhritiman Das Oliver R. Wearn Russell J. Gray Al John C. Cabanas Andaman Chankhao Apinya Saisamorn Badrul Azhar Benjamin P. Y.-H. Lee Benoit Goossens Carl Traeholt David W. MacDonald Emilia A. Lastica-Ternura Fernando Garcia-Gil Freddy Pattiselanno Gabriella Fredriksson Glyn Davies Harry Hilser Jamiee Wheelhouse Jan van der Ploeg John Carlo Redeña-Santos Jonathan M. Moore Karmila Parakkasi Laura Marie Berman Samuel Xin Tham Lee Liam J. Hughes Lukemann Haqeem Alen Marc Ancrenaz Marcus A. H. Chua Markus Handschuh Matthew Ward Mohamad Arif Rifqi Mohammad Aliyuddin Bin Jaini Muhammad Syazwan Bin Omar Nantachai Pongpattananurak NayMyo Shwe Olivia Z. Daniel Pablo Sinovas Parag Deka Radinal Ret Thaung Robert M. Ewers Romain Legrand Ronglarp Sukmasuang Sally Soo Kaicheen Salwa Khalid Saw Soe Aung Sheherazade Sheherazade Stuart J. Davies Thiemo Braasch Thomas N. E. Gray Tim Redford Ulmar Grafe Xiaoyang Song Matthew Scott Luskin School of the Environment University of Queensland Brisbane QLD Australia Borneo Futures Bandar Seri Begawan Brunei Durrell Institute of Conservation and Ecology (DICE) University of Kent Canterbury UK Division of Biological Sciences and Wildlife Biology Program University of Montana Missoula Montana USA World Wildlife Fund Malaysia Sabah Office Kota Kinabalu Malaysia Institute of Biodiversity and Environmental Conservation Universiti Malaysia Sarawak Kota Samarahan Malaysia Department of Biology Faculty of Mathematics and Natural Sciences University of Indonesia University of Indonesia Depok Indonesia Southeast Asia Rainforest Research Partnership (SEARPP) Kota Kinabalu Malaysia Wildlife Conservation Research Unit Department of Biology University of Oxford Oxford UK Association Anoulak Luang Prabang Lao PDR SSC Wild Pig Specialist Group IUCN Heidelberg Germany Wildlife Conservation Society Indonesia Program Jakarta Indonesia Conservation Ecology Program School of Bioresources and Technology King Mongkut's University of Technology Thonburi Bangkok Thailand Pygmy Hog Conservation Programme Durrell Wildlife Conservation Trust Jersey UK Fauna & Flora International Vietnam Program Hanoi Vietnam Save Vietnam's Wildlife Hoa Lư Vietnam Global Initiative Against Transnational Organized Crime (GI-TOC) Geneva Switzerland Mathematics and Natural Sciences Southern Luzon State University Lucban Philippines Department of Forest Biology Kasetsart University Bangkok Thailand Universiti Putra Malaysia Serdang Malaysia Wildlife & Natural Heritage Royal Commission for AlUla Riyadh Saudi Arabia Danau Girang Field Centre Kota Kinabalu Malaysia Organisms and Environment Division Cardiff School of Biosciences Cardiff University Cardiff UK Research and Conservation Division Copenhagen Zoo Copenhagen Denmark University of the Philippines Los Baños Philippines D'ABOVILLE Foundation and Demo Farm Inc. San Jose Philippines Universitas Papua Manokwari West Papua In

The 2018 arrival of African swine fever (ASF) in China was followed by reports of wild pig deaths across most countries in Southeast Asia. However, the magnitude and duration of population-level impacts of ASF on wild pig species remain unclear. To elucidate the spatiotemporal spread of ASF in the region for native pig species, we gathered qualitative information on wild pig population dynamics in Southeast Asia between 2018 and 2024 from 88 expert elicitation questionnaires representing sites in 11 countries. Peak reported population declines occurred in 2021 and 2022, with more than half of respondents reporting declining wild pig populations, far higher than in earlier years. The reported declines waned to 44.23% in 2024, whereas simultaneously, the number of populations reported to be “increasing” increased from 11.3%–13.2% in 2019–2022 to 28.9% in 2024. These reports suggest that the ASF outbreak may have peaked for wild boars and bearded pigs in mainland Southeast Asia, Borneo, and Sumatra, with some subsequent recovery. However, the disease is still expanding into the ranges of island endemic species, such as new reports for the Sulawesi warty pig ( Sus celebensis ) in September of 2024. Island endemics remain particularly vulnerable to extinction from ASF and require urgent monitoring and conservation action.

关键词： bearded pig (Sus barbatus) biodiversity monitoring expert elicitation survey predator-prey depletion Suidaeisland endemics threatened and endangered species wildlife disease ecology wild boar (Sus scrofa) zoonotic virus

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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021

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The Lancet Infectious Diseases 2025年第5期25卷 519-536页

作者： Kyu, Hmwe Hmwe Vongpradith, Avina Dominguez, Regina-Mae Villanueva Ma, Jianing Albertson, Samuel B. Novotney, Amanda Khalil, Ibrahim A. Troeger, Christopher E. Doxey, Matthew C. Ledesma, Jorge R. Sirota, Sarah Brooke Bender, Rose Grace Swetschinski, Lucien R. Cunningham, Matthew Spearman, Sandra Abate, Yohannes Habtegiorgis Abd Al Magied, Abdallah H.A. El Hafeez, Samar Abd Abdoun, Meriem Abera, Bayeh Abidi, Hassan Aboagye, Richard Gyan Abtew, Yonas Derso Abualruz, Hasan Abu-Gharbieh, Eman Abukhadijah, Hana J. Aburuz, Salahdein Addo, Isaac Yeboah Adekanmbi, Victor Adetunji, Charles Oluwaseun Oluwaseun Adeyeoluwa, Temitayo Esther Adhikary, Ripon Kumar Adnani, Qorinah Estiningtyas Sakilah Adra, Saryia Adzigbli, Leticia Akua Afolabi, Aanuoluwapo Adeyimika Afzal, Muhammad Sohail Afzal, Saira Agampodi, Suneth Buddhika Agide, Feleke Doyore Ahinkorah, Bright Opoku Ahmad, Aqeel Ahmad, Sajjad Ahmed, Ayman Ahmed, Haroon Ahmed, Saeed Akinosoglou, Karolina Akter, Ema Al Awaidy, Salah Alajlani, Muaaz M. Alam, Khurshid Albakri, Almaza Albashtawy, Mohammed Aldhaleei, Wafa A. Algammal, Abdelazeem M. Al-Gheethi, Adel Ali Saeed Ali, Abid Ali, Syed Shujait Ali, Waad Alif, Sheikh Mohammad Aljunid, Syed Mohamed Al-Marwani, Sabah Almazan, Joseph Uy Al-Mekhlafi, Hesham M. Almustanyir, Sami Alqahatni, Saleh A. Alrawashdeh, Ahmad Al-Rifai, Rami H. Alsabri, Mohammed A. Altaf, Awais Altirkawi, Khalid A. Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Alyahya, Mohammad Sharif Ibrahim Al-Zyoud, Walid A. Amugsi, Dickson A. Andrei, Catalina Liliana Antoni, Sebastien Anuoluwa, Boluwatife Stephen Anuoluwa, Iyadunni Adesola Anwar, Saleha Anwari, Palwasha Apostol, Geminn Louis Carace Arabloo, Jalal Arafat, Mosab Aravkin, Aleksandr Y. Areda, Demelash Aregawi, Brhane Berhe Aremu, Abdulfatai Arndt, Michael Benjamin Asgedom, Akeza Awealom Ashraf, Tahira Athari, Seyyed Shamsadin Atreya, Alok Ayele, Firayad Azadi, Davood Azhar, Gulrez Shah Aziz, Shahkaar Azzam, Ahmed Y. Babu, Giridhara Rathnaiah Taghanaki, Pegah Bahrami Bahramian, Saeed Balakrishnan, Senthi Department of Health Metrics Sciences School of Medicine Institute for Health Metrics and Evaluation University of Washington Seattle 98195 WA United States Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Center for Biostatistics Ohio State University Columbus OH United States Department of Global Health University of Washington Seattle WA United States Urban Indian Health Institute Seattle Indian Health Board Seattle WA United States School of Medicine Yale University New Haven CT United States Department of Clinical Governance and Quality Improvement Aleta Wondo General Hospital Aleta Wondo Ethiopia College of Pharmacy Ajman University Ajman United Arab Emirates Department of Epidemiology Alexandria University Alexandria Egypt Department of Medicine University of Sétif Algeria Sétif Algeria Department of Health Sétif Algeria Department of Medical Microbiology Bahir Dar University Bahir Dar Ethiopia Department of Biology Ghent University Ghent Belgium Laboratory Technology Sciences Department Yasuj University of Medical Sciences Yasuj Iran Department of Family and Community Health University of Health and Allied Sciences Ho Ghana Department of Biomedical Science Arba Minch University Arba Minch Ethiopia Department of Nursing Al Zaytoonah University of Jordan Amman Jordan Amman Jordan Department of Clinical Sciences Sharjah United Arab Emirates Department of Biopharmaceutics and Clinical Pharmacy University of Jordan Amman Jordan Medical Research Center-Academic Health System Hamad Medical Corporation Doha Qatar College of Pharmacy University of Jordan Amman Jordan Department of Therapeutics United Arab Emirates University Al Ain United Arab Emirates School of Medicine University of Sydney Sydney NSW Australia Centre for Social Research in Health University of New South Wales Syd

Background: Diarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age groups of children younger than 5 years are scarce, and the burden in children older than 5 years and in adults is also understudied. We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to assess the burden of, and trends in, diarrhoeal diseases overall and attributable to 13 pathogens, as well as the contributions of associated risk factors, in children and adults in 204 countries and territories from 1990 to 2021. Methods: We used the Cause of Death Ensemble modelling strategy to analyse vital registration data, verbal autopsy data, mortality surveillance data, and minimally invasive tissue sampling data. We used DisMod-MR (version 2.1), a Bayesian meta-regression tool, to analyse incidence and prevalence data identified via systematic reviews, population-based surveys, and claims and inpatient data. We calculated diarrhoeal disability-adjusted life-years (DALYs) as the sum of years of life lost (YLLs) and years lived with disability (YLDs) for each location, year, and age–sex group. For aetiology estimation, we used a counterfactual approach to quantify population-attributable fractions (PAFs). Additionally, we estimated the diarrhoeal disease burden attributable to the independent effects of risk factors using the comparative risk assessment framework. Findings: In 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. In 2021, an e

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Measurements of the Temperature and E-mode Polarization of the Cosmic Microwave Background from the Full 500-square-degree SPTpol Dataset

arXiv

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arXiv 2025年

作者： Chou, T.-L. Ade, P.A.R. Anderson, A.J. Austermann, J.E. Balkenhol, L. Beall, J.A. Bender, A.N. Benson, B.A. Bianchini, F. Bleem, L.E. Carlstrom, J.E. Chang, C.L. Chaubal, P. Chiang, H.C. Citron, R. Moran, C. Corbett Crawford, T.M. Crites, A.T. de Haan, T. Dobbs, M.A. Dutcher, D. Everett, W. Gallicchio, J. George, E.M. Gupta, N. Halverson, N.W. Holder, G.P. Holzapfel, W.L. Hrubes, J.D. Huang, N. Hubmayr, J. Irwin, K.D. Knox, L. Lee, A.T. Li, D. Lowitz, A. McMahon, J.J. Montgomery, J. Natoli, T. Nibarger, J.P. Noble, G.I. Novosad, V. Omori, Y. Padin, S. Patil, S. Pryke, C. Quan, W. Reichardt, C.L. Ruhl, J.E. Saliwanchik, B.R. Schaffer, K.K. Sievers, C. Smecher, G. Stark, A.A. Tucker, C. Veach, T. Vieira, J.D. Wang, G. Whitehorn, N. Wu, W.L.K. Yefremenko, V. Zebrowski, J.A. Department of Astronomy and Astrophysics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Cardiff University CardiffCF10 3XQ United Kingdom Fermi National Accelerator Laboratory MS209 P.O. Box 500 BataviaIL60510 United States NIST Quantum Devices Group 325 Broadway Mailcode 817.03 BoulderCO80305 United States Department of Physics University of Colorado BoulderCO80309 United States Sorbonne Universit’e CNRS UMR 7095 Institut d’Astrophysique de Paris 98 bis bd Arago Paris75014 France High Energy Physics Division Argonne National Laboratory 9700 S. Cass Avenue ArgonneIL60439 United States SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo ParkCA94025 United States Department of Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Enrico Fermi Institute University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States School of Physics University of Melbourne ParkvilleVIC3010 Australia Department of Physics McGill University 3600 Rue University MontrealQCH3A 2T8 Canada School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Durban South Africa University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Jet Propulsion Laboratory PasadenaCA91109 United States Department of Physics Cornell University IthacaNY United States Department of Astronomy Cornell University IthacaNY United States Department of Physics University of California BerkeleyCA94720 United States Physics Division Lawrence Berkeley National Laboratory BerkeleyCA94720 United States Ibaraki Tsukuba305-0801 Japan Canadian Institute for Advanced Research CIFAR Program in Gravity and the Extreme Universe TorontoONM5G 1Z8 Canada Joseph Henry Laboratories of Physics Jadwin Hall Princeton University PrincetonNJ08544

Using the full four-year SPTpol 500 deg2 dataset in both the 95 GHz and 150 GHz frequency bands, we present measurements of the temperature and E-mode polarization of the cosmic microwave background (CMB), as well as the E-mode polarization auto-power spectrum (EE) and temperature-E-mode cross-power spectrum (TE) in the angular multipole range 50 0 = 70.48 ± 2.16 km s−1 Mpc−1 and Ωm = 0.271 ± 0.026, when using only the SPTpol data and a Planck-based prior on the optical depth to reionization. The ΛCDM parameter constraints are consistent across the 95 GHz-only, 150 GHz-only, TE-only, and EE-only data splits. Between the 1000 data splits, the ΛCDM parameter constraints are borderline consistent at the ∼ 2σ level. This consistency improves when including a parameter AL, the degree of lensing of the CMB inferred from the smearing of acoustic peaks. When marginalized over AL, the ΛCDM parameter constraints from SPTpol are consistent with those from Planck. The power spectra presented here are the most sensitive measurements of the lensed CMB damping tail to date for roughly > 1700 in TE and > 2000 in EE. Copyright © 2025, The Authors. All rights reserved.

关键词： Cosmology

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Correction to: European first-year university students accept evolution but lack substantial knowledge about it: a standardized European cross-country assessment

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Evolution: Education and Outreach 2022年第1期15卷 1-2页

作者： Paul Kuschmierz Dittmar Graf Anna Beniermann Alexander Bergmann Rianne Pinxten Tuomas Aivelo Justyna Berniak-Woźny Gustav Bohlin Anxela Bugallo-Rodriguez Lucia Vazquez-Ben Pedro Cardia Bento Filipe Barreiras Pinto Cavadas Umran Betul Cebesoy Lütfullah Türkmen Dragana D. Cvetković Emilie Demarsy Mirko S. Đorđević Uroš B. Savković Szymon M. Drobniak Liudmyla Dubchak Radka M. Dvořáková Jana Fančovičová Corinne Fortin Momir Futo Nicoleta Adriana Geamănă Niklas Gericke Donato A. Grasso Ádám Z. Lendvai Zoltán Németh Evangelia Mavrikaki Andra Meneganzin Telmo Pievani Athanasios Mogias Andrea Möller Paulo G. Mota Yamama Naciri Katarzyna Ożańska-Ponikwia Silvia Paolucci Péter László Pap Maria Petersson Barbara Pietrzak Alma Pobric Juris Porozovs Giulia Realdon Xana Sá-Pinto Mathieu Sicard Mircea T. Sofonea Andrej Sorgo Alexandru N. Stermin Ioan Tăușan Gregor Torkar Slavica Tutnjević Anna E. Uitto Máté Varga Mirna Varga Konstantinos Korfiatis Enrique Viguera Lisa Christine Virtbauer Albena Vutsova Inmaculada Yruela Jelle Zandveld Institute for Didactics of Biology Justus-Liebig-University Giessen Giessen Germany Institute for Biology Teaching and Learning Research in Biology Education Humboldt-Universität Zu Berlin Berlin Germany Faculty of Life Science Department of Biology University of Leipzig Leipzig Germany Didactica Research Unit Faculty of Social Sciences & Behavioural Ecology & Ecophysiology Group Department of Biology University of Antwerp Antwerp Belgium Organismal and Evolutionary Biology Research Program University of Helsinki Helsinki Finland University of Information Technology and Management in Rzeszów Rzeszów Poland Public & Science (VA) Stockholm Sweden Department of Pedagogy and Didactics University of A Coruña A Coruña Spain Escola Superior de Educação Politécnico Do Porto Porto Portugal Department of Science and Mathematics Polytechnic Institute of Santarém/School of Education Santarém Portugal Faculty of Education/Department of Mathematics and Science Education Usak University Uşak Turkey Chair of Genetics and Evolution Faculty of Biology University of Belgrade Belgrade Serbia Department of Botany and Plant Biology University of Geneva Geneva Switzerland Department of Evolutionary Biology Institute for Biological Research Siniša Stanković”—National Institute of Republic of Serbia University of Belgrade Belgrade Serbia Institute of Environmental Sciences Jagiellonian University Kraków Poland Department of Parliamentarism and Political Management National Academy for Public Administration Under the President of Ukraine Kiev Ukraine Department of Teaching and Didactics of Biology Charles University Prague Czech Republic Department of Biology Faculty of Education Trnava University Trnava Slovakia Laboratory of Didactic André Revuz University of Paris Paris France Institut Ruđer Bošković/Division of Molecular Biology Zagreb Croatia Department/Research Center in Systems Ecology and Sustainability University of Bucharest Bucharest Romania Department of Enviro

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DESHIMA on ASTE: On-sky responsivity calibration of the integrated superconducting spectrometer

arXiv

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arXiv 2020年

作者： Takekoshi, Tatsuya Karatsu, Kenichi Suzuki, Junya Tamura, Yoichi Oshima, Tai Taniguchi, Akio 'IchiroAsayama, Shin Bakx, Tom J. L. C. Baselmans, Jochem J. A. Bosma, Sjoerd Bueno, Juan Chin, Kah Wuy Fujii, Yasunori Fujita, Kazuyuki Huiting, Robert Ikarashi, Soh Ishida, Tsuyoshi Ishii, Shun Kawabe, Ryohei Klapwijk, Teun M. Kohno, Kotaro Kouchi, Akira Llombart, Nuria Maekawa, Jun Murugesan, Vignesh Nakatsubo, Shunichi Naruse1, Masato Ohtawara, Kazushige Laguna, Alejandro Pascual Suzuki, Koyo Thoen, David J. Tsukagoshi, Takashi Ueda, Tetsutaro Visser, Pieter J. De Werf, Paul P. Vander Yates, Stephen J. C. Yoshimura, Yuki Yurduseven, Ozan Endo, Akira Institute of Astronomy Graduate School of Science University of Tokyo 2-21-1 Osawa Mitaka Tokyo181-0015 Japan Graduate School of Informatics and Engineering University of Electro-Communications Cho-fu Tokyo182-8585 Japan SRON-Netherlands Institute for Space Research Sorbonnelaan 2 Utrecht3584 Netherlands Faculty of Electrical Engineering Mathematics and Computer Science Delft University of Technology Mekelweg 4 Delft2628 Netherlands Department of Physics Kyoto University Kyoto606-8502 Japan High Energy Accelerator Research Organization 1-1 Oho Tsukuba Ibaraki305-0801 Japan Division of Particle and Astrophysical Science Graduate School of Science Nagoya University Aichi464-8602 National Astronomical Observatory of Japan Mitaka Tokyo181-8588 Japan Graduate University for Advanced Studies 2-21-1 Osawa Mitaka Tokyo181-0015 School of Physics and Astronomy Cardiff University Parade CardiffCF243AA United Kingdom Department of Astronomy School of Science University of Tokyo Bunkyo Tokyo113-0033 Institute of Low Temperature Science Hokkaido University Sapporo060-0819 Japan Joint ALMA Observatory Alonso de Cordova 3107 Vitacura Santiago Kavli Institute of NanoScience Faculty of Applied Sciences Delft University of Technology Lorentzweg 1 Delft2628 Netherlands Physics Department Moscow State Pedagogical University Moscow119991 Russia Research Center for the Early Universe Graduate School of Science University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan Institute of Space and Astronautical Science Japan Aerospace Exploration Agency Sagamihara252-5210 Japan Graduate School of Science and Engineering Saitama University 255 Shimo-okubo Sakura Saitama338-8570 Japan

We are developing an ultra-wideband spectroscopic instrument, DESHIMA (DEep Spectroscopic HIgh-redshift MApper), based on the technologies of an on-chip filter-bank and Microwave Kinetic Inductance Detector (MKID) to investigate dusty star-burst galaxies in the distant universe at millimeter and submillimeter wavelength. An on-site experiment of DESHIMA was performed using the ASTE 10-m telescope. We established a responsivity model that converts frequency responses of the MKIDs to line-of-sight brightness temperature. We estimated two parameters of the responsivity model using a set of skydip data taken under various precipitable water vapor (PWV, 0.4-3.0 mm) conditions for each MKID. The line-of-sight brightness temperature of sky is estimated using an atmospheric transmission model and the PWVs. As a result, we obtain an average temperature calibration uncertainty of 1δ =4%, which is smaller than other photometric biases. In addition, the average forward efficiency of 0.88 in our responsivity model is consistent with the value expected from the geometrical support structure of the *** also estimate line-of-sight PWVs of each skydip observation using the frequency response of MKIDs, and confirm the consistency with PWVs reported by the Atacama Large Millimeter/submillimeter Array. Copyright © 2020, The Authors. All rights reserved.

关键词： Calibration

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Measurement of the total and differential cross-sections of tt¯W production in pp collisions at s = 13 TeV with the ATLAS detector

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Journal of High Energy Physics 2024年第5期2024卷 131页

作者： Aad, G. Abbott, B. Abeling, K. Abicht, N.J. Abidi, S.H. Aboulhorma, A. Abramowicz, H. Abreu, H. Abulaiti, Y. Abusleme Hoffman, A.C. Acharya, B.S. Adam Bourdarios, C. Adamczyk, L. Adamek, L. Addepalli, S.V. Addison, M.J. Adelman, J. Adiguzel, A. Adye, T. Affolder, A.A. Afik, Y. Agaras, M.N. Agarwala, J. Aggarwal, A. Agheorghiesei, C. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ahuja, S. Ai, X. Aielli, G. Ait Tamlihat, M. Aitbenchikh, B. Aizenberg, I. Akbiyik, M. Åkesson, T.P.A. Akimov, A.V. Akiyama, D. Akolkar, N.N. Al Khoury, K. Alberghi, G.L. Albert, J. Albicocco, P. Albouy, G.L. Alderweireldt, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, A. Alfonsi, F. Algren, M. Alhroob, M. Ali, B. Ali, H.M.J. Ali, S. Alibocus, S.W. Aliev, M. Alimonti, G. Alkakhi, W. Allaire, C. Allbrooke, B.M.M. Allen, J.F. Allendes Flores, C.A. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Alvarez Estevez, M. Alvarez Fernandez, A. Alviggi, M.G. Aly, M. Amaral Coutinho, Y. Ambler, A. Amelung, C. Amerl, M. Ames, C.G. Amidei, D. Amor Dos Santos, S.P. Amos, K.R. Ananiev, V. Anastopoulos, C. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Antrim, D.J.A. Anulli, F. Aoki, M. Aoki, T. Aparisi Pozo, J.A. Aparo, M.A. Aperio Bella, L. Appelt, C. Apyan, A. Aranzabal, N. Arcangeletti, C. Arce, A.T.H. Arena, E. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Armbruster, A.J. Arnaez, O. Arnold, H. Arrubarrena Tame, Z.P. Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Assamagan, K. Astalos, R. Atashi, S. Atkin, R.J. Atkinson, M. Atlay, N.B. Atmani, H. Atmasiddha, P.A. Augsten, K. Auricchio, S. Auriol, A.D. Austrup, V.A. Avolio, G. Axiotis, K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Bachiu, A. Backman, F. Badea, A. Bagnaia, P. Bahmani, M. Bailey, A.J. Bailey, V.R. Baines, J.T. Baines, L. Bakalis, C. Baker, O.K. Bakos, E. Bakshi Gupta, D. Balasubramanian, R. Baldin, E.M. Balek, P. Ballabene, E. Balli, F. Baltes, L.M. Balunas, W. Department of Physics University of Adelaide Adelaide Australia Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Université Savoie Mont Blanc CNRS/IN2P3 Annecy France APC Université Paris Cité CNRS/IN2P3 Paris France High Energy Physics Division Argonne National Laboratory Argonne IL United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d’Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China School of Science Shenzhen Campus of Sun Yat-sen University Shenzhen China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Einstein Center for Fundamental Physics and Laboratory for High Energy Physics University of Bern Bern Switzerland School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziantep University Gaziantep Turkey Department of Physics

Measurements of inclusive and differential production cross-sections of a top-quark-top-antiquark pair in association with a W boson (tt¯W) are presented. They are performed by targeting final states with two same-sign or three isolated leptons (electrons or muons) and are based on s = 13 TeV proton-proton collision data with an integrated luminosity of 140 fb⁻¹, recorded from 2015 to 2018 with the ATLAS detector at the Large Hadron Collider. The inclusive tt¯W production cross-section is measured to be 880 ± 80 fb, compared to a reference theoretical prediction of 745 ± 50 (scale) ± 13 (2-loop approx.) ± 19 (PDF, α_s) fb. Differential cross-section measurements characterise this process in detail for the first time. Several particle-level observables are compared with a variety of theoretical predictions, which generally agree well with the normalised differential cross-section results. Additionally, the relative charge asymmetry of tt¯W⁺ and tt¯W⁻ is measured inclusively to be A_C^rel = 0.33 ± 0.05, in very good agreement with the theoretical prediction of 0.322 ± 0.003 (scale) ± 0.007 (PDF), as well as differentially. © The Author(s) 2024.

关键词： Hadron-Hadron Scattering Top Physics

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A search for R-parity-violating supersymmetry in final states containing many jets in pp collisions at s = 13 TeV with the ATLAS detector

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Journal of High Energy Physics 2024年第5期2024卷 3页

作者： Aad, G. Abbott, B. Abeling, K. Abicht, N.J. Abidi, S.H. Aboulhorma, A. Abramowicz, H. Abreu, H. Abulaiti, Y. Acharya, B.S. Adam Bourdarios, C. Adamczyk, L. Addepalli, S.V. Addison, M.J. Adelman, J. Adiguzel, A. Adye, T. Affolder, A.A. Afik, Y. Agaras, M.N. Agarwala, J. Aggarwal, A. Agheorghiesei, C. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ahuja, S. Ai, X. Aielli, G. Aikot, A. Ait Tamlihat, M. Aitbenchikh, B. Aizenberg, I. Akbiyik, M. Åkesson, T.P.A. Akimov, A.V. Akiyama, D. Akolkar, N.N. Aktas, S. Al Khoury, K. Alberghi, G.L. Albert, J. Albicocco, P. Albouy, G.L. Alderweireldt, S. Alegria, Z.L. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, F. Algren, M. Alhroob, M. Ali, B. Ali, H.M.J. Ali, S. Alibocus, S.W. Aliev, M. Alimonti, G. Alkakhi, W. Allaire, C. Allbrooke, B.M.M. Allen, J.F. Allendes Flores, C.A. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Alvarez Estevez, M. Alvarez Fernandez, A. Alves Cardoso, M. Alviggi, M.G. Aly, M. Amaral Coutinho, Y. Ambler, A. Amelung, C. Amerl, M. Ames, C.G. Amidei, D. Amor Dos Santos, S.P. Amos, K.R. Ananiev, V. Anastopoulos, C. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Anulli, F. Aoki, M. Aoki, T. Aparisi Pozo, J.A. Aparo, M.A. Aperio Bella, L. Appelt, C. Apyan, A. Aranzabal, N. Arbiol Val, S.J. Arcangeletti, C. Arce, A.T.H. Arena, E. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Arnaez, O. Arnold, H. Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Assamagan, K. Astalos, R. Atashi, S. Atkin, R.J. Atkinson, M. Atmani, H. Atmasiddha, P.A. Augsten, K. Auricchio, S. Auriol, A.D. Austrup, V.A. Avolio, G. Axiotis, K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Bachiu, A. Backman, F. Badea, A. Baer, T.M. Bagnaia, P. Bahmani, M. Bahner, D. Bai, K. Bailey, A.J. Bailey, V.R. Baines, J.T. Baines, L. Baker, O.K. Bakos, E. Bakshi Gupta, D. Balakrishnan, V. Balasubramanian, R. Baldin, E.M. Balek, P. Ballabene, E. Balli, F. Baltes, L.M. Balunas, W.K. Balz, Department of Physics University of Adelaide Adelaide Australia Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Université Savoie Mont Blanc CNRS/IN2P3 Annecy France APC Université Paris Cité CNRS/IN2P3 Paris France High Energy Physics Division Argonne National Laboratory Argonne IL United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d’Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China School of Science Shenzhen Campus of Sun Yat-sen University Shenzhen China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory Berkeley CA United States University of California Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Einstein Center for Fundamental Physics and Laboratory for High Energy Physics University of Bern Bern Switzerland School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziant

A search for R-parity-violating supersymmetry in final states with high jet multiplicity is presented. The search uses 140 fb−1 of proton-proton collision data at s = 13 TeV collected by the ATLAS experiment during Ru... 详细信息

A search for R-parity-violating supersymmetry in final states with high jet multiplicity is presented. The search uses 140 fb⁻¹ of proton-proton collision data at s = 13 TeV collected by the ATLAS experiment during Run 2 of the Large Hadron Collider. The results are interpreted in the context of R-parity-violating supersymmetry models that feature prompt gluino-pair production decaying directly to three jets each or decaying to two jets and a neutralino which subsequently decays promptly to three jets. No significant excess over the Standard Model expectation is observed and exclusion limits at the 95% confidence level are extracted. Gluinos with masses up to 1800 GeV are excluded when decaying directly to three jets. In the cascade scenario, gluinos with masses up to 2340 GeV are excluded for a neutralino with mass up to 1250 GeV. © The Author(s) 2024.

关键词： Beyond Standard Model Hadron-Hadron Scattering Jets Supersymmetry

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The Brain Tumor Segmentation (BraTS) Challenge 2023: Glioma Segmentation in Sub-Saharan Africa Patient Population (BraTS-Africa)

arXiv

引用

arXiv 2023年

作者： Adewole, Maruf Rudie, Jeffrey D. Gbdamosi, Anu Toyobo, Oluyemisi Raymond, Confidence Zhang, Dong Omidiji, Olubukola Akinola, Rachel Suwaid, Mohammad Abba Emegoakor, Adaobi Ojo, Nancy Aguh, Kenneth Kalaiwo, Chinasa Babatunde, Gabriel Ogunleye, Afolabi Gbadamosi, Yewande Iorpagher, Kator Calabrese, Evan Aboian, Mariam Linguraru, Marius Albrecht, Jake Wiestler, Benedikt Kofler, Florian Janas, Anastasia LaBella, Dominic Kzerooni, Anahita Fathi Li, Hongwei Bran Iglesias, Juan Eugenio Farahani, Keyvan Eddy, James Bergquist, Timothy Chung, Verena Shinohara, Russell Takeshi Wiggins, Walter Reitman, Zachary Wang, Chunhao Liu, Xinyang Jiang, Zhifan Familiar, Ariana Van Leemput, Koen Bukas, Christina Piraud, Maire Conte, Gian-Marco Johansson, Elaine Meier, Zeke Menze, Bjoern H. Baid, Ujjwal Bakas, Spyridon Dako, Farouk Fatade, Abiodun Anazodo, Udunna C. Lagos Nigeria Department of Radiation Biology Radiotherapy and Radiodiagnosis University of Lagos Lagos Nigeria Department of Radiology University of California San Diego United States Crestview Radiology Limited Lagos Nigeria Lagos University Teaching Hospital Lagos Nigeria Lagos State University Teaching Hospital Lagos Ikeja Nigeria NSIA-Kano Diagnostic Center Kano Nigeria Nnamdi Azikiwe University Teaching Hospital Anambra State Nnewi Nigeria Federal Medical Centre Ogun State Abeokuta Nigeria Federal Medical Centre Abia State Umuahia Nigeria National Hospital Abuja FCT Nigeria Benue State University Teaching Hospital Benue State Makurdi Nigeria Duke University Medical Center Department of Radiology United States University of California San FranciscoCA United States Yale University New HavenCT United States Children's National Hospital WashingtonDC United States George Washington University WashingtonDC United States Sage Bionetworks United States Department of Neuroradiology Technical University of Munich Munich Germany Helmholtz Research Center Munich Germany Duke University Medical Center Department of Radiation Oncology United States Children’s Hospital of Philadelphia University of Pennsylvania PhiladelphiaPA United States University of Pennsylvania PhiladelphiaPA United States Athinoula A Martinos Center for Biomedical Imaging Massachusetts General Hospital BostonMA United States University of Zurich Switzerland Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD20814 United States Center for Clinical Epidemiology and Biostatistics University of Pennsylvania Philadelphia United States Department of Applied Mathematics and Computer Science Technical University of Denmark Denmark Mayo Clinic MN United States Precision FDA U.S. Food and Drug Administration Silver SpringMD United States Booz Allen Hamilton McLeanVA United States Department of Radiology Perelman School of Medicine U

Gliomas are the most common type of primary brain tumors. Although gliomas are relatively rare, they are among the deadliest types of cancer, with a survival rate of less than 2 years after diagnosis. Gliomas are challenging to diagnose, hard to treat and inherently resistant to conventional therapy. Years of extensive research to improve diagnosis and treatment of gliomas have decreased mortality rates across the Global North, while chances of survival among individuals in low- and middle-income countries (LMICs) remain unchanged and are significantly worse in Sub-Saharan Africa (SSA) populations. Long-term survival with glioma is associated with the identification of appropriate pathological features on brain MRI and confirmation by histopathology. Since 2012, the Brain Tumor Segmentation (BraTS) Challenge have evaluated state-of-the-art machine learning methods to detect, characterize, and classify gliomas. However, it is unclear if the state- of-the-art methods can be widely implemented in SSA given the extensive use of lower-quality MRI technology, which produces poor image contrast and resolution and more importantly, the propensity for late presentation of disease at advanced stages as well as the unique characteristics of gliomas in SSA (i.e., suspected higher rates of gliomatosis cerebri). Thus, the BraTS-Africa Challenge provides a unique opportunity to include brain MRI glioma cases from SSA in global efforts through the BraTS Challenge to develop and evaluate computer-aided-diagnostic (CAD) methods for the detection and characterization of glioma in resource-limited settings, where the potential for CAD tools to transform healthcare are more likely. © 2023, CC BY.

关键词： Tumors

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The ASNR-MICCAI Brain Tumor Segmentation (BraTS) Challenge 2023: Intracranial Meningioma

arXiv

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arXiv 2023年

作者： LaBella, Dominic Adewole, Maruf Alonso-Basanta, Michelle Altes, Talissa Anwar, Syed Muhammad Baid, Ujjwal Bergquist, Timothy Bhalerao, Radhika Chen, Sully Chung, Verena Conte, Gian-Marco Dako, Farouk Eddy, James Ezhov, Ivan Godfrey, Devon Hilal, Fathi Familiar, Ariana Farahani, Keyvan Iglesias, Juan Eugenio Jiang, Zhifan Johanson, Elaine Kazerooni, Anahita Fathi Kent, Collin Kirkpatrick, John Koer, Florian Van Leemput, Koen Li, Hongwei Bran Liu, Xinyang Mahtabfar, Aria McBurney-Lin, Shan McLean, Ryan Meier, Zeke Moawad, Ahmed W. Mongan, John Nedelec, Pierre Pajot, Maxence Piraud, Marie Rashid, Arif Reitman, Zachary Shinohara, Russell Takeshi Velichko, Yury Wang, Chunhao Warman, Pranav Wiggins, Walter Aboian, Mariam Albrecht, Jake Anazodo, Udunna Bakas, Spyridon Flanders, Adam Janas, Anastasia Khanna, Goldey Linguraru, Marius George Menze, Bjoern Nada, Ayman Rauschecker, Andreas M. Rudie, Jeff Tahon, Nourel Hoda Villanueva-Meyer, Javier Wiestler, Benedikt Calabrese, Evan Department of Radiation Oncology Duke University Medical Center DurhamNC United States Lab Crestview Radiology Lagos Nigeria Department of Radiation Oncology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Missouri University ColumbiaMO United States Children's National Hospital WashingtonDC United States George Washington University WashingtonDC United States University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Sage Bionetworks United States University of California San Francisco CA United States Duke University Medical Center School of Medicine United States Mayo Clinic MN United States Center for Global Health Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Informatics Technical University Munich Germany TranslaTUM Central Institute for Translational Cancer Research Technical University of Munich Germany Children's Hospital of Philadelphia University of Pennsylvania PhiladelphiaPA United States Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD20814 United States Athinoula A Martinos Center for Biomedical Imaging Massachusetts General Hospital BostonMA United States PrecisionFDA U.S. Food and Drug Administration Silver SpringMD United States Helmholtz Ai Helmholtz Munich Germany Department of Diagnostic and Interventional Neuroradiology School of Medicine Klinikum Rechts der Isar Technical University of Munich Germany Department of Applied Mathematics and Computer Science Technical University of Denmark Denmark Department of Neuroradiology Technical University of Munich Munich Germany University of Zurich Switzerland Department of Neurosurgery Thomas Jefferson Univer

Meningiomas are the most common primary intracranial tumor in adults and can be associated with significant morbidity and mortality. Radiologists, neurosurgeons, neuro-oncologists, and radiation oncologists rely on multiparametric MRI (mpMRI) for diagnosis, treatment planning, and longitudinal treatment monitoring;yet automated, objective, and quantitative tools for non-invasive assessment of meningiomas on mpMRI are lacking. The BraTS meningioma 2023 challenge will provide a community standard and benchmark for state-of-the-art automated intracranial meningioma segmentation models based on the largest expert annotated multilabel meningioma mpMRI dataset to date. Challenge competitors will develop automated segmentation models to predict three distinct meningioma sub-regions on MRI including enhancing tumor, non-enhancing tumor core, and surrounding nonenhancing T2/FLAIR hyperintensity. Models will be evaluated on separate validation and held-out test datasets using standardized metrics utilized across the BraTS 2023 series of challenges including the Dice similarity coefficient and Hausdorff distance. The models developed during the course of this challenge will aid in incorporation of automated meningioma MRI segmentation into clinical practice, which will ultimately improve care of patients with meningioma. Copyright © 2023, The Authors. All rights reserved.

关键词： Tumors

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A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation (vol 10, 4779 , 2019)

引用

NATURE COMMUNICATIONS 2019年第1期10卷 1-16页

作者： Tavernier, S. J. Athanasopoulos, V. Verloo, P. Behrens, G. Staal, J. Bogaert, D. J. Naesens, L. De Bruyne, M. Van Gassen, S. Parthoens, E. Ellyard, J. Cappello, J. Morris, L. X. Van Gorp, H. Van Isterdael, G. Saeys, Y. Lamkanfi, M. Schelstraete, P. Dehoorne, J. Bordon, V. Van Coster, R. Lambrecht, B. N. Menten, B. Beyaert, R. Vinuesa, C. G. Heissmeyer, V. Dullaers, M. Haerynck, F. Primary Immune Deficiency Research Lab Department of Internal Medicine and Pediatrics Centre for Primary Immunodeficiency Ghent Jeffrey Modell Diagnosis and Research Centre Ghent University Hospital Ghent Belgium VIB Center for Inflammation Research Unit of Molecular Signal Transduction in Inflammation Ghent Belgium Department of Biomedical Molecular Biology Ghent University Ghent Belgium Department of Immunology and Infectious Disease and Center for Personalised Immunology (NHMRC Centre for Research Excellence) John Curtin School of Medical Research Australian National University Canberra Australia Centre for Personalised Immunology (CACPI) Shanghai Renji Hospital Shanghai Jiao Tong University Shanghai China Department of Internal Medicine and Pediatrics Division of Pediatric Neurology and Metabolism Ghent University Hospital Ghent Belgium Institute for Immunology Biomedical Center Ludwig-Maximilians-Universität München Planegg-Martinsried Germany Research Unit Molecular Immune Regulation Helmholtz Zentrum München Munich Germany Department of Internal Medicine and Pediatrics Division of Pediatric Immunology and Pulmonology Ghent University Hospital Ghent Belgium Department of Internal Medicine and Pediatrics Ghent University Hospital Ghent Belgium Center for Medical Genetics Ghent University Hospital Ghent Belgium VIB Center for Inflammation Research Unit of Data Mining and Modeling for Biomedicine Ghent Belgium Department of Applied Mathematics Computer Science and Statistics Ghent University Gent Belgium VIB Bioimaging Core VIB Center for Inflammation Research Ghent Belgium The Australian Phenomics Facility John Curtin School of Medical Research Australian National University Canberra Australia VIB Center for Inflammation Research Ghent Belgium VIB Flow Core VIB Center for Inflammation Research Ghent Belgium Department of Internal Medicine and Pediatrics Division of Pediatric Rheumatology Ghent University Hospital Ghent Belgium Department of Inter

Hyperinflammatory syndromes are life-threatening disorders caused by overzealous immune cell activation and cytokine release, often resulting from defects in negative feedback mechanisms. In the quintessential hyperinflammatory syndrome familial hemophagocytic lymphohistiocytosis (HLH), inborn errors of cytotoxicity result in effector cell accumulation, immune dysregulation and, if untreated, tissue damage and death. Here, we describe a human case with a homozygous nonsense R688* RC3H1 mutation suffering from hyperinflammation, presenting as relapsing HLH. RC3H1 encodes Roquin-1, a posttranscriptional repressor of immune-regulatory proteins such as ICOS, OX40 and TNF. Comparing the R688* variant with the murine M199R variant reveals a phenotypic resemblance, both in immune cell activation, hypercytokinemia and disease development. Mechanistically, R688* Roquin-1 fails to localize to P-bodies and interact with the CCR4-NOT deadenylation complex, impeding mRNA decay and dysregulating cytokine production. The results from this unique case suggest that impaired Roquin-1 function provokes hyperinflammation by a failure to quench immune activation.

关键词： Disease genetics Inflammation Primary immunodeficiency disorders RNA decay

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