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Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)

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NATURE COMMUNICATIONS 2022年第1期13卷 1-1页

作者： Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi

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First Constraints on the Epoch of Reionization Using the non-Gaussianity of the Kinematic Sunyaev-Zel’dovich Effect from the South Pole Telescope and Herschel-SPIRE Observations

arXiv

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arXiv 2024年

作者： Raghunathan, S. Ade, P.A.R. Anderson, A.J. Ansarinejad, B. Archipley, M. Austermann, J.E. Balkenhol, L. Beall, J.A. Benabed, K. Bender, A.N. Benson, B.A. Bianchini, F. Bleem, L.E. Bock, J. Bouchet, F.R. Bryant, L. Camphuis, E. Carlstrom, J.E. Cecil, T.W. Chang, C.L. Chaubal, P. Chiang, H.C. Chichura, P.M. Chou, T.-L. Citron, R. Coerver, A. Crawford, T.M. Crites, A.T. Cukierman, A. Daley, C. Dibert, K.R. Dobbs, M.A. Doussot, A. Dutcher, D. Everett, W. Feng, C. Ferguson, K.R. Fichman, K. Foster, A. Galli, S. Gallicchio, J. Gambrel, A.E. Gardner, R.W. Ge, F. George, E.M. Goeckner-Wald, N. Gualtieri, R. Guidi, F. Guns, S. Gupta, N. de Haan, T. Halverson, N.W. Hivon, E. Holder, G.P. Holzapfel, W.L. Hood, J.C. Hrubes, J.D. Hryciuk, A. Huang, N. Hubmayr, J. Irwin, K.D. Kéruzoré, F. Khalife, A.R. Knox, L. Korman, M. Kornoelje, K. Kuo, C.-L. Lee, A.T. Levy, K. Li, D. Lowitz, A.E. Lu, C. Maniyar, A. Martsen, E.S. McMahon, J.J. Menanteau, F. Millea, M. Montgomery, J. Moran, C. Corbett Nakato, Y. Natoli, T. Nibarger, J.P. Noble, G.I. Novosad, V. Omori, Y. Padin, S. Pan, Z. Paschos, P. Patil, S. Phadke, K.A. Prabhu, K. Pryke, C. Quan, W. Rahimi, M. Rahlin, A. Reichardt, C.L. Rouble, M. Ruhl, J.E. Saliwanchik, B.R. Schaffer, K.K. Schiappucci, E. Sievers, C. Smecher, G. Sobrin, J.A. Stark, A.A. Stephen, J. Suzuki, A. Tandoi, C. Thompson, K.L. Thorne, B. Trendafilova, C. Tucker, C. Umilta, C. Veach, T. Vieira, J.D. Viero, M.P. Wan, Y. Wang, G. Whitehorn, N. Wu, W.L.K. Yefremenko, V. Young, M.R. Zebrowski, J.A. Zemcov, M. Center for AstroPhysical Surveys National Center for Supercomputing Applications UrbanaIL61801 United States School of Physics and Astronomy Cardiff University CardiffCF24 3YB United Kingdom Fermi National Accelerator Laboratory MS209 P.O. Box 500 BataviaIL60510 United States Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Astronomy and Astrophysics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States School of Physics University of Melbourne ParkvilleVIC3010 Australia Department of Astronomy University of Illinois Urbana-Champaign 1002 West Green Street UrbanaIL61801 United States NIST Quantum Devices Group 325 Broadway Mailcode 817.03 BoulderCO80305 United States Department of Physics University of Colorado BoulderCO80309 United States Institut d’Astrophysique de Paris UMR 7095 CNRS & Sorbonne Université 98 bis boulevard Arago Paris75014 France High-Energy Physics Division Argonne National Laboratory 9700 South Cass Avenue. LemontIL60439 United States Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall StanfordCA94305 United States Department of Physics Stanford University 382 Via Pueblo Mall StanfordCA94305 United States SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo ParkCA94025 United States California Institute of Technology PasadenaCA91125 United States Jet Propulsion Laboratory California Institute of Technology PasadenaCA91109 United States Enrico Fermi Institute University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics McGill Space Institute McGill University 3600 Rue University MontrealQCH3A 2T8 Canada School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Durban South Africa Unive

We report results from an analysis aimed at detecting the trispectrum of the kinematic Sunyaev-Zel’dovich (kSZ) effect by combining data from the South Pole Telescope (SPT) and Herschel-SPIRE experiments over a 100 deg2 field. The SPT observations combine data from the previous and current surveys, namely SPTpol and SPT-3G, to achieve depths of 4.5, 3, and 16 µK-arcmin in bands centered at 95, 150, and 220 GHz. For SPIRE, we include data from the 600 and 857 GHz bands. We reconstruct the velocity-induced large-scale correlation of the small-scale kSZ signal with a quadratic estimator that uses two cosmic microwave background (CMB) temperature maps, constructed by optimally combining data from all the frequency bands. We reject the null hypothesis of a zero trispectrum at 10.3σ level. However, the measured trispectrum contains contributions from both the kSZ and other undesired components, such as CMB lensing and astrophysical foregrounds, with kSZ being sub-dominant. We use the Agora simulations to estimate the expected signal from CMB lensing and astrophysical foregrounds. After accounting for the contributions from CMB lensing and foreground signals, we do not detect an excess kSZ-only trispectrum and use this non-detection to set constraints on reionization. By applying a prior based on observations of the Gunn-Peterson trough, we obtain an upper limit on the duration of reionization of (formula presented). We find these constraints are fairly robust to foregrounds assumptions. This trispectrum measurement is independent of, but consistent with, Planck’s optical depth measurement. This result is the first constraint on the epoch of reionization using the non-Gaussian nature of the kSZ signal. © 2024, CC BY.

关键词： Kinematics

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Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers Abstracts

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FLUIDS AND BARRIERS OF THE CNS 2017年第SUPPL 2期14卷 27-27页

作者： [Anonymous] The Jerzy Kukuczka Academy of Physical Education Katowice Poland The Institute of Animal Physiology and Food Research Polish Academy of Sciences Olsztyn Poland University of Miami Miami FL USA Institute of Pharmaceutical Science King’s College London London United Kingdom Department of Ophthalmology and Molecular and Integrative Physiology The University of Michigan Ann Arbor MI USA Department of Internal Medicine and Cardiology The University of Michigan Ann Arbor MI USA School of Medicine Department of Cellular and Molecular Medicine Koc University Istanbul Turkey Department of Cellular and Molecular Medicine Medical Faculty Koc University Istanbul Turkey Department of Neuroscience School of Medicine Koc University Istanbul Turkey Department of Neuroscience Medical Faculty Koc University Istanbul Turkey Department of Laboratory Animals Science Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey Department of Neuroscience Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey School of Medicine Koc University Istanbul Turkey Department of Forensic Science Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Histology and Embryology School of Medicine Koc University Istanbul Turkey Department of Histology and Embryology Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Physiology School of Medicine Koc University Istanbul Turkey Theodor Kocher Institute University of Bern Bern Switzerland Institute of Veterinary Physiology Vetsuisse Faculty University of Zurich Zurich Switzerland Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Zurich Center of Integrative Human Physiology University of Zurich Zurich Switzerland Institute for Veterinary Physiology and Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Institute of Veterinary Physiology Univer

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Erratum to: Methods for evaluating medical tests and biomarkers

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Diagnostic and prognostic research 2017年第1期1卷 11页

作者： Gowri Gopalakrishna Miranda Langendam Rob Scholten Patrick Bossuyt Mariska Leeflang Anna Noel-Storr James Thomas Iain Marshall Byron Wallace Penny Whiting Clare Davenport Gowri GopalaKrishna Isabel de Salis Sue Mallett Robert Wolff Richard Riley Marie Westwood Jos Kleinen Gary Collins Hans Reitsma Karel Moons Antonia Zapf Annika Hoyer Katharina Kramer Oliver Kuss J Ensor J J Deeks E C Martin R D Riley Gerta Rücker Susanne Steinhauser Martin Schumacher Joie Ensor Kym Snell Brian Willis Thomas Debray Jon Deeks Lavinia Ferrante di Ruffano Sian Taylor-Phillips Chris Hyde Stuart A Taylor Gauraang Batnagar Lavinia Ferrante Di Ruffano Farah Seedat Aileen Clarke Sarah Byron Frances Nixon Rebecca Albrow Thomas Walker Carla Deakin Zhivko Zhelev Harriet Hunt Yaling Yang Lucy Abel James Buchanan Thomas Fanshawe Bethany Shinkins Laure Wynants Jan Verbakel Sabine Van Huffel Dirk Timmerman Ben Van Calster Aeliko Zwinderman Jason Oke Jack O'Sullivan Rafael Perera Brian Nicholson Hannah L Bromley Tracy E Roberts Adele Francis Denniis Petrie G Bruce Mann Kinga Malottki Holly Smith Lucinda Billingham Alice Sitch Oke Gerke Mie Holm-Vilstrup Eivind Antonsen Segtnan Ulrich Halekoh Poul Flemming Høilund-Carlsen Bernard G Francq Jac Dinnes Julie Parkes Walter Gregory Jenny Hewison Doug Altman William Rosenberg Peter Selby Julien Asselineau Paul Perez Aïssatou Paye Emilie Bessede Cécile Proust-Lima Christiana Naaktgeboren Joris de Groot Anne Rutjes Johannes Reitsma Emmanuel Ogundimu Jonathan Cook Yannick Le Manach Yvonne Vergouwe Romin Pajouheshnia Rolf Groenwold Karen Moons Linda Peelen Daan Nieboer Bavo De Cock Micael J Pencina Ewout W Steyerberg Jennifer Cooper Nick Parsons Chris Stinton Steve Smith Andy Dickens Rachel Jordan Alexandra Enocson David Fitzmaurice Peymane Adab Charles Boachie Gaj Vidmar Karoline Freeman Martin Connock Rachel Court Carl Moons Jessica Harris Andrew Mumford Zoe Plummer Kurtis Lee Barnaby Reeves Chris Rogers Veerle Verheyden Gianni D Angelini Gavin J Murphy Jeremy Huddy Melody Ni Katherine Good Graham Cooke 1Department of Clinical Epidemiology Biostatistics & Bioinformatics Academic Medical Center University of Amsterdam Amsterdam The Netherlands. 2Cochrane Netherlands Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Utrecht Netherlands. 234Department of Clinical Epidemiology Biostatistics & Bioinformatics Academic Medical Center University of Amsterdam Amsterdam The Netherlands. 49Department of Clinical Epidemiology Biostatistics & Bioinformatics Academic Medical Center University of Amsterdam Amsterdam The Netherlands. 3Cochrane Dementia and Cognitive Improvement Group University of Oxford Oxford UK. 4EPPI-Centre Department of Social Science University College London London UK. 5Division of Health and Social Care Research King's College London London UK. 6College of Computer and Information Science Northeastern University Boston USA. 13University Hospitals Bristol NHS Foundation Trust School of Social and Community Medicine Bristol UK. 275Institute of Applied Health Research University of Birmingham Birmingham UK. 9Department of Clinical Epidemiology Biostatistics & Bioinformatics Academic Medical Center University of Amsterdam Amsterdam The Netherlands. 10School of Social and Community Medicine University of Bristol Bristol UK. 179Institute of Applied Health Research University of Birmingham Birmingham UK. 12Kleijnen Systematic Reviews Ltd York UK. 25Research Institute for Primary Care and Health Sciences Keele University Keele UK. 188Centre for Statistics in Medicine Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences University of Oxford Oxford UK. 191Julius Center for Health Sciences and Primary Care University Medical Center Utrecht 3584 CG Utrecht Netherlands. 237Julius Center for Health Sciences and Primary Care University Medical Center Utrecht 3584 CG Utrecht Netherlands. 18Department of Medical Statistics University Medical Center Göttingen Göttingen Germany. 19Institute for B

[This corrects the article DOI: 10.1186/s41512-016-0001-y.].

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The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

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Nature Communications 2022年第1期13卷 1-14页

作者： Reiner, Robert C. Welgan, Catherine A. Troeger, Christopher E. Baumann, Mathew M. Weiss, Daniel J. Deshpande, Aniruddha Blacker, Brigette F. Miller-Petrie, Molly K. Earl, Lucas Bhatt, Samir Abolhassani, Hassan Abosetugn, Akine Eshete Abu-Gharbieh, Eman Adekanmbi, Victor Adetokunboh, Olatunji O. Aghaali, Mohammad Aji, Budi Alahdab, Fares Al-Aly, Ziyad Alhassan, Robert Kaba Ali, Saqib Alizade, Hesam Aljunid, Syed Mohamed Almasi-Hashiani, Amir Al-Mekhlafi, Hesham M. Altirkawi, Khalid A. Alvis-Guzman, Nelson Amare, Azmeraw T. Amini, Saeed Amugsi, Dickson A. Ancuceanu, Robert Andrei, Catalina Liliana Ansari, Fereshteh Anvari, Davood Appiah, Seth Christopher Yaw Arabloo, Jalal Aremu, Olatunde Atout, Maha Moh’d Wahbi Ausloos, Marcel Ausloos, Floriane Ayanore, Martin Amogre Aynalem, Yared Asmare Azene, Zelalem Nigussie Badawi, Alaa Baig, Atif Amin Banach, Maciej Bedi, Neeraj Bhagavathula, Akshaya Srikanth Bhandari, Dinesh Bhardwaj, Nikha Bhardwaj, Pankaj Bhattacharyya, Krittika Bhutta, Zulfiqar A. Bijani, Ali Birhanu, Tesega Tesega Mengistu Bitew, Zebenay Workneh Boloor, Archith Brady, Oliver J. Butt, Zahid A. Car, Josip Carvalho, Felix Casey, Daniel C. Chattu, Vijay Kumar Chowdhury, Mohiuddin Ahsanul Kabir Chu, Dinh-Toi Coelho, Camila H. Cook, Aubrey J. Damiani, Giovanni Daoud, Farah Gela, Jiregna Darega Darwish, Amira Hamed Daryani, Ahmad Das, Jai K. Davis Weaver, Nicole Deribe, Kebede Desalew, Assefa Dharmaratne, Samath Dhamminda Dianatinasab, Mostafa Diaz, Daniel Djalalinia, Shirin Dorostkar, Fariba Dubljanin, Eleonora Duko, Bereket Dwyer-Lindgren, Laura Effiong, Andem El Sayed Zaki, Maysaa El Tantawi, Maha Enany, Shymaa Fattahi, Nazir Feigin, Valery L. Fernandes, Eduarda Ferrara, Pietro Fischer, Florian Foigt, Nataliya A. Folayan, Morenike Oluwatoyin Foroutan, Masoud Frostad, Joseph Jon Fukumoto, Takeshi Gaidhane, Abhay Motiramji Gebrekrstos, Hailemikael Gebrekidan G. K. Gebremeskel, Leake Gebreslassie, Assefa Ayalew Gething, Peter W. Gezae, Kebede Embaye Ghadiri, Keyghobad Ghashghaee, Ahmad Golechha, Mahaveer Gubar Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Malaria Atlas Project University of Oxford Oxford United Kingdom Imperial College London London United Kingdom Department of Laboratory Medicine Karolinska University Hospital Huddinge Sweden Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Department of Public Health Debre Berhan University Debre Berhan Ethiopia Department of Clinical Sciences University of Sharjah Sharjah United Arab Emirates Population Health Sciences King’s College London London United Kingdom Centre of Excellence for Epidemiological Modelling and Analysis Stellenbosch University Stellenbosch South Africa Department of Global Health Stellenbosch University Cape Town South Africa Department of Epidemiology and Biostatistics Qom University of Medical Sciences Qom Iran Faculty of Medicine and Public Health Jenderal Soedirman University Purwokerto Indonesia Mayo Evidence-based Practice Center Mayo Clinic Foundation for Medical Education and Research Rochester MN United States John T. Milliken Department of Internal Medicine Washington University in St. Louis St. Louis MO United States Clinical Epidemiology Center Department of Veterans Affairs St Louis MO United States Institute of Health Research University of Health and Allied Sciences Ho Ghana Department of Information Systems College of Economics and Political Science Sultan Qaboos University Muscat Oman Infectious and Tropical Disease Research Center Hormozgan University of Medical Sciences Bandar Abbas Iran Department of Health Policy and Management Kuwait University Safat Kuwait International Centre for Casemix and Clinical Coding National University of Malaysia Bandar Tun Razak Malaysia Department of Epidemiology Arak University of Medical Sciences Arak Iran Medical Research Center

Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their combined burden. Here we synthesise subnational estimates of the burden of LRIs, diarrhoea, and malaria in children under-5 from 2000 to 2017 for 43 sub-Saharan countries. Some units faced a relatively equal burden from each of the three diseases, while others had one or two dominant sources of unit-level burden, with no consistent pattern geographically across the entire subcontinent. Using a subnational counterfactual analysis, we show that nearly 300 million DALYs could have been averted since 2000 by raising all units to their national average. Our findings are directly relevant for decision-makers in determining which and targeting where the most appropriate interventions are for increasing child survival. © 2022, The Author(s).

关键词： Biogeography Epidemiology Infectious diseases Malaria

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Asteroid Measurements at Millimeter Wavelengths with the South Pole Telescope

arXiv

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arXiv 2022年

作者： Chichura, P.M. Foster, A. Patel, C. Ossa-Jaen, N. Ade, P.A.R. Ahmed, Z. Anderson, A.J. Archipley, M. Austermann, J.E. Avva, J.S. Balkenhol, L. Barry, P.S. Thakur, R. Basu Beall, J.A. Benabed, K. Bender, A.N. Benson, B.A. Bianchini, F. Bleem, L.E. Bouchet, F.R. Bryant, L. Byrum, K. Carlstrom, J.E. Carter, F.W. Cecil, T.W. Chang, C.L. Chaubal, P. Chen, G. Chiang, H.C. Cho, H.-M. Chou, T.-L. Citron, R. Cliche, J.-F. Crawford, T.M. Crites, A.T. Cukierman, A. Daley, C.M. Denison, E.V. Dibert, K. Ding, J. Dobbs, M.A. Dutcher, D. Everett, W. Feng, C. Ferguson, K.R. Fu, J. Galli, S. Gallicchio, J. Gambrel, A.E. Gardner, R.W. George, E.M. Goeckner-Wald, N. Gualtieri, R. Guns, S. Gupta, N. Guyser, R. de Haan, T. Halverson, N.W. Harke-Hosemann, A.H. Harrington, N.L. Henning, J.W. Hilton, G.C. Hivon, E. Holder, G.P. Holzapfel, W.L. Hood, J.C. Howe, D. Hrubes, J.D. Huang, N. Hubmayr, J. Irwin, K.D. Jeong, O.B. Jonas, M. Jones, A. Khaire, T.S. Knox, L. Kofman, A.M. Korman, M. Kubik, D.L. Kuhlmann, S. Kuo, C.-L. Lee, A.T. Leitch, E.M. Li, D. Lowitz, A. Lu, C. Marrone, D.P. McMahon, J.J. Meyer, S.S. Michalik, D. Millea, M. Mocanu, L.M. Montgomery, J. Moran, C. Corbett Nadolski, A. Natoli, T. Nguyen, H. Nibarger, J.P. Noble, G. Novosad, V. Omori, Y. Padin, S. Pan, Z. Paschos, P. Patil, S. Pearson, J. Phadke, K.A. Posada, C.M. Prabhu, K. Pryke, C. Quan, W. Rahlin, A. Reichardt, C.L. Riebel, D. Riedel, B. Rouble, M. Ruhl, J.E. Saliwanchik, B.R. Sayre, J.T. Schaffer, K.K. Schiappucci, E. Shirokoff, E. Sievers, C. Smecher, G. Sobrin, J.A. Springmann, A. Stark, A.A. Stephen, J. Story, K.T. Suzuki, A. Tandoi, C. Thompson, K.L. Thorne, B. Tucker, C. Umilta, C. Vale, L.R. Veach, T. Vieira, J.D. Wang, G. Whitehorn, N. Wu, W.L.K. Yefremenko, V. Yoon, K.W. Young, M.R. Department of Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics Case Western Reserve University ClevelandOH44106 United States Department of Physics University of Illinois Urbana-Champaign 1110 West Green Street UrbanaIL61801 United States Department of Physics University of Redlands 1267 East Colton Ave RedlandsCA92374 United States School of Physics and Astronomy Cardiff University CardiffCF24 3YB United Kingdom Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall StanfordCA94305 United States SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo ParkCA94025 United States Fermi National Accelerator Laboratory MS209 P.O. Box 500 BataviaIL60510 United States Department of Astronomy University of Illinois at Urbana-Champaign 1002 West Green Street UrbanaIL61801 United States Center for AstroPhysical Surveys National Center for Supercomputing Applications UrbanaIL61801 United States NIST Quantum Devices Group 325 Broadway Mailcode 817.03 BoulderCO80305 United States Department of Physics University of Colorado BoulderCO80309 United States Department of Physics University of California BerkeleyCA94720 United States School of Physics University of Melbourne ParkvilleVIC3010 Australia High-Energy Physics Division Argonne National Laboratory 9700 South Cass Avenue. ArgonneIL60439 United States California Institute of Technology 1200 East California Boulevard. PasadenaCA91125 United States Institut d'Astrophysique de Paris UMR 7095 CNRS Sorbonne Université 98 bis boulevard Arago Paris75014 France Department of Astronomy and Astrophysics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics Stanford University 382 Via Pueblo Mall StanfordCA94305 United St

We present the first measurements of asteroids in millimeter wavelength (mm) data from the South Pole Telescope (SPT), which is used primarily to study the cosmic microwave background (CMB). We analyze maps of two ∼ 270 deg2 sky regions near the ecliptic plane, each observed with the SPTpol camera ∼ 100 times over one month. We subtract the mean of all maps of a given field, removing static sky signal, and then average the mean-subtracted maps at known asteroid locations. We detect three asteroids-(324) Bamberga, (13) Egeria, and (22) Kalliope-with signal-to-noise ratios (S/N) of 11.2, 10.4, and 6.1, respectively, at 2.0 mm (150 GHz);we also detect (324) Bamberga with S/N of 4.1 at 3.2 mm (95 GHz). We place constraints on these asteroids' effective emissivities, brightness temperatures, and light curve modulation amplitude. Our flux density measurements of (324) Bamberga and (13) Egeria roughly agree with predictions, while our measurements of (22) Kalliope suggest lower flux, corresponding to effective emissivities of 0.64±0.11 at 2.0 mm and Copyright © 2022, The Authors. All rights reserved.

关键词： Cameras

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A demonstration of improved constraints on primordial gravitational waves with delensing

arXiv

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arXiv 2020年

作者： Ade, P.A.R. Ahmed, Z. Amiri, M. Anderson, A.J. Austermann, J.E. Avva, J.S. Barkats, D. Thakur, R. Basu Beall, J.A. Bender, A.N. Benson, B.A. Bianchini, F. Bischoff, C.A. Bleem, L.E. Bock, J.J. Boenish, H. Bullock, E. Buza, V. Carlstrom, J.E. Chang, C.L. Cheshire, J.R. Chiang, H.C. Chou, T.-L. Citron, R. Connors, J. Moran, C. Corbett Cornelison, J. Crawford, T.M. Crites, A.T. Crumrine, M. Cukierman, A. de Haan, T. Dierickx, M. Dobbs, M.A. Duband, L. Everett, W. Fatigoni, S. Filippini, J.P. Fliescher, S. Gallicchio, J. George, E.M. Germaine, T.St. Goeckner-Wald, N. Goldfinger, D.C. Grayson, J. Gupta, N. Hall, G. Halpern, M. Halverson, N.W. Harrison, S. Henderson, S. Henning, J.W. Hildebrandt, S.R. Hilton, G.C. Holder, G.P. Holzapfel, W.L. Hrubes, J.D. Huang, N. Hubmayr, J. Hui, H. Irwin, K.D. Kang, J. Karkare, K.S. Karpel, E. Kefeli, S. Kernasovskiy, S.A. Knox, L. Kovac, J.M. Kuo, C.L. Lau, K. Lee, A.T. Leitch, E.M. Li, D. Lowitz, A. Manzotti, A. McMahon, J.J. Megerian, K.G. Meyer, S.S. Millea, M. Mocanu, L.M. Moncelsi, L. Montgomery, J. Nadolski, A. Namikawa, T. Natoli, T. Netterfield, C.B. Nguyen, H.T. Nibarger, J.P. Noble, G. Novosad, V. O’Brient, R. Ogburn, R.W. Omori, Y. Padin, S. Palladino, S. Patil, S. Prouve, T. Pryke, C. Racine, B. Reichardt, C.L. Reintsema, C.D. Richter, S. Ruhl, J.E. Saliwanchik, B.R. Schaffer, K.K. Schillaci, A. Schmitt, B.L. Schwarz, R. Sheehy, C.D. Sievers, C. Smecher, G. Soliman, A. Stark, A.A. Steinbach, B. Sudiwala, R.V. Teply, G.P. Thompson, K.L. Tolan, J.E. Tucker, C. Turner, A.D. Umiltà, C. Veach, T. Vieira, J.D. Vieregg, A.G. Wandui, A. Wang, G. Weber, A.C. Whitehorn, N. Wiebe, D.V. Willmert, J. Wong, C.L. Wu, W.L. Kimmy Yang, H. Yefremenko, V. Yoon, K.W. Young, E. Yu, C. Zeng, L. Zhang, C. Cardiff University CardiffCF10 3XQ United Kingdom SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo ParkCA94025 United States Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall StanfordCA94305 United States Department of Physics and Astronomy University of British Columbia VancouverBCV6T 1Z1 Canada Fermi National Accelerator Laboratory MS209 P.O. Box 500 BataviaIL60510 United States NIST Quantum Devices Group 325 Broadway Mailcode 817.03 BoulderCO80305 United States Department of Physics University of Colorado BoulderCO80309 United States Department of Physics University of California BerkeleyCA94720 United States Harvard-Smithsonian Center for Astrophysics 60 Garden Street CambridgeMA02138 United States California Institute of Technology MS 249-17 1216 E. California Blvd. PasadenaCA91125 United States High Energy Physics Division Argonne National Laboratory 9700 S. Cass Avenue ArgonneIL60439 United States Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Astronomy and Astrophysics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States School of Physics University of Melbourne ParkvilleVIC3010 Australia Department of Physics University of Cincinnati CincinnatiOH45221 United States Jet Propulsion Laboratory PasadenaCA91109 United States Department of Physics Harvard University CambridgeMA02138 United States Minnesota Institute for Astrophysics University of Minnesota MinneapolisMN55455 United States Department of Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Enrico Fermi Institute University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics McGill University 3600 Rue University MontrealQCH3A 2T8 Canada School of Mathematics Statistics & Computer Science University of KwaZulu-Natal

We present a constraint on the tensor-to-scalar ratio, r, derived from measurements of cosmic microwave background (CMB) polarization B-modes with "delensing," whereby the uncertainty on r contributed by the sample variance of the gravitational lensing B-modes is reduced by cross-correlating against a lensing B-mode template. This template is constructed by combining an estimate of the polarized CMB with a tracer of the projected large-scale structure. The large-scale-structure tracer used is a map of the cosmic infrared background derived from Planck satellite data, while the polarized CMB map comes from a combination of South Pole Telescope, Bicep/Keck, and Planck data. We expand the Bicep/Keck likelihood analysis framework to accept a lensing template and apply it to the Bicep/Keck data set collected through 2014 using the same parametric foreground modelling as in the previous analysis. From simulations, we find that the uncertainty on r is reduced by ∼ 10%, from σ(r)= 0.024 to 0.022, which can be compared with a ∼ 26% reduction obtained when using a perfect lensing template or if there were zero lensing B-modes. Applying the technique to the real data, the constraint on r is improved from r0.05 Copyright © 2020, The Authors. All rights reserved.

关键词： Cosmology

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The cluster heritage project with XMM-Newton: Mass assembly and thermodynamics at the endpoint of structure formation I. programme overview

arXiv

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arXiv 2020年

作者： Arnaud, M. Ettori, S. Pratt, Gabriel W. Rossetti, M. Eckert, D. Gastaldello, F. Gavazzi, R. Kay, S.T. Lovisari, L. Maughan, B.J. Pointecouteau, E. Sereno, M. Bartalucci, I. Bonafede, A. Bourdin, H. Cassano, R. Duffy, R.T. Iqbal, A. Maurogordato, S. Rasia, E. Sayers, J. Andrade-Santos, F. Aussel, H. Barnes, D.J. Barrena, R. Borgani, S. Burkutean, S. Clerc, N. Corasaniti, P.-S. Cuillandre, J.-C. de Grandi, S. de Petris, M. Dolag, K. Donahue, M. Ferragamo, A. Gaspari, M. Ghizzardi, S. Gitti, M. Haines, C.P. Jauzac, M. Johnston-Hollitt, M. Jones, C. Kéruzoré, F. LeBrun, A.M.C. Mayet, F. Mazzotta, P. Melin, J.-B. Molendi, S. Nonino, M. Okabe, N. Paltani, S. Perotto, L. Pires, S. Radovich, M. Rubino-Martin, J.-A. Salvati, L. Saro, A. Sartoris, B. Schellenberger, G. Streblyanska, A. Tarrío, P. Tozzi, P. Umetsu, K. van der Burg, R.F.J. Vazza, F. Venturi, T. Yepes, G. Zarattini, S. AIM CEA CNRS Université Paris-Saclay Université Paris Diderot Sorbonne Paris Cité Gif-sur-YvetteF-91191 France INAF Osservatorio di Astrofisica e Scienza dello Spazio via Pietro Gobetti 93/3 Bologna40129 Italy INFN Sezione di Bologna viale Berti Pichat 6/2 BolognaI-40127 Italy INAF IASF-Milano via A. Corti 12 MilanoI-20133 Italy Department of Astronomy University of Geneva ch. d'Écogia 16 VersoixCH-1290 Switzerland CNRS Sorbonne Université UMR 7095 Institut d'Astrophysique de Paris 98 bis Boulevard Arago Paris75014 France Jodrell Bank Centre for Astrophysics Department of Physics and Astronomy School of Natural Sciences The University of Manchester ManchesterM13 9PL United Kingdom Center for Astrophysics | Harvard & Smithsonian 60 Garden Street CambridgeMA02138 United States HH Wills Physics Laboratory University of Bristol Tyndall Ave BristolBS8 1TL United Kingdom IRAP Université de Toulouse CNRS CNES UPS 9 av du colonel Roche BP44346 Toulouse Cedex 431028 France Dipartimento di Fisica e Astronomia Universitá di Bologna Via Gobetti 92/3 Bologna40121 Italy INAF Istituto di Radio Astronomia Via Gobetti 101 Bologna40129 Italy Hamburger Sternwarte Gojenbergsweg 112 Hamburg21029 Germany Università degli studi di Roma Tor Vergata via della ricerca scientifica 1 Roma00133 Italy Université Côte d'Azur Observatoire de la Côte d'Azur CNRS Laboratoire Lagrange Nice France INAF - Osservatorio Astronomico di Trieste via Tiepolo 11 TriesteI-34131 Italy IFPU - Institute for Fundamental Physics of the Universe via Beirut 2 Trieste34151 Italy California Institute of Technology PasadenaCA91125 United States Department of Physics Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA02139 United States C/ Vía Láctea s/n La Laguna TenerifeE-38205 Spain Universidad de La Laguna Departamento de Astrofísica C/ Astrofísico Francisco Sánchez s/n La Laguna TenerifeE-38206 Spain D

The Cluster HEritage project with XMM-Newton - Mass Assembly and Thermodynamics at the Endpoint of structure formation (CHEX-MATE) is a three-mega-second Multi-Year Heritage programme to obtain X-ray observations of a minimally-biased, signal-to-noise-limited sample of 118 galaxy clusters detected by Planck through the Sunyaev-Zeldovich effect. The programme, described in detail in this paper, aims to study the ultimate products of structure formation in time and mass. It is composed of a census of the most recent objects to have formed (Tier-1: 0.05 14 M 500 14 M), together with a sample of the highest mass objects in the Universe (Tier-2: z 500 > 7.25 × 1014 M). The programme will yield an accurate vision of the statistical properties of the underlying population, measure how the gas properties are shaped by collapse into the dark matter halo, uncover the provenance of non-gravitational heating, and resolve the major uncertainties in mass determination that limit the use of clusters for cosmological parameter estimation. We will acquire X-ray exposures of uniform depth, designed to obtain individual mass measurements accurate to 15 − 20% under the hydrostatic assumption. We present the project motivations, describe the programme definition, and detail the ongoing multi-wavelength observational (lensing, SZ, radio) and theoretical effort that is being deployed in support of the project. Copyright © 2020, The Authors. All rights reserved.

关键词： Thermodynamics

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Simultaneous Millimeter-wave, Gamma-ray, and Optical Monitoring of the Blazar PKS 2326-502 During a Flaring State

arXiv

引用

arXiv 2023年

作者： Hood, J.C. Simpson, A. McDaniel, A. Foster, A. Ade, P.A.R. Ajello, M. Anderson, A.J. Austermann, J.E. Beall, J.A. Bender, A.N. Benson, B.A. Bianchini, F. Bleem, L.E. Carlstrom, J.E. Chang, C.L. Chaubal, P. Chiang, H.C. Chou, T.-L. Citron, R. Corbett Moran, C. Crawford, T.M. Crites, A.T. De Haan, T. Dobbs, M.A. Everett, W. Gallicchio, J. George, E.M. Gupta, N. Halverson, N.W. Hilton, G.C. Holder, G.P. Holzapfel, W.L. Hrubes, J.D. Huang, N. Hubmayr, J. Irwin, K.D. Knox, L. Lee, A.T. Li, D. Lowitz, A. Madejski, G. Malkan, M. McMahon, J.J. Meyer, S.S. Montgomery, J. Natoli, T. Nibarger, J.P. Noble, G. Novosad, V. Omori, Y. Padin, S. Patil, S. Pryke, C. Reichardt, C.L. Ruhl, J.E. Saliwanchik, B.R. Schaffer, K.K. Sievers, C. Smecher, G. Stark, A.A. Tucker, C. Veach, T. Vieira, J.D. Wang, G. Whitehorn, N. Wu, W.L.K. Yefremenko, V. Zebrowski, J.A. Zhang, L. Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Astronomy and Astrophysics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics and Astronomy Vanderbilt University NashvilleTN37235 United States Department of Physics Rensselaer Polytechnic Institute TroyNY12180 United States Department of Physics and Astronomy Clemson University ClemsonSC29631 United States Department of Physics Case Western Reserve University ClevelandOH44106 United States Cardiff University CardiffCF10 3XQ United Kingdom Fermi National Accelerator Laboratory MS209 P.O. Box 500 BataviaIL60510 United States Nist Quantum Devices Group 325 Broadway Mailcode 817.03 BoulderCO80305 United States Department of Physics University of Colorado BoulderCO80309 United States High Energy Physics Division Argonne National Laboratory 9700 S. Cass Avenue ArgonneIL60439 United States School of Physics University of Melbourne VIC Parkville3010 Australia Department of Physics University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Enrico Fermi Institute University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Department of Physics McGill University 3600 Rue University QC MontrealH3A 2T8 Canada School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Durban South Africa University of Chicago 5640 South Ellis Avenue ChicagoIL60637 United States Tapir Walter Burke Institute for Theoretical Physics California Institute of Technology 1200 E California Blvd PasadenaCA91125 United States Dunlap Institute for Astronomy & Astrophysics University of Toronto 50 St George St ON TorontoM5S 3H4 Canada Department of Astronomy & Astrophysics University of Toronto 50 St George St ON TorontoM5S 3H4 Canada Ibaraki Tsukuba305-0801 Japan Ibaraki Tsukuba305-0801 Japan Canadian Institute f

Including millimeter-wave (mm-wave) data in multi-wavelength studies of the variability of active galactic nuclei (AGN) can provide insights into AGN physics that are not easily accessible at other wavelengths. We demonstrate in this work the potential of cosmic microwave background (CMB) telescopes to provide long-term, high-cadence mm-wave AGN monitoring over large fractions of sky. We report on a pilot study using data from the SPTpol instrument on the South Pole Telescope (SPT), which was designed to observe the CMB at arcminute and larger angular scales. Between 2013 and 2016, SPTpol was used primarily to observe a single 500 deg2field, covering the entire field several times per day with detectors sensitive to radiation in bands centered at 95 and 150 GHz. We use SPT 150 GHz observations to create AGN light curves, and we compare these mm-wave light curves to those at other wavelengths, in particular γ-ray and optical. In this Letter, we focus on a single source, PKS 2326-502, which has extensive, day-timescale monitoring data in gamma-ray, optical, and now mm-wave between 2013 and 2016. We find PKS 2326-502 to be in a flaring state in the first two years of this monitoring, and we present a search for evidence of correlated variability between mm-wave, optical R band, and γ-ray observations. This pilot study is paving the way for AGN monitoring with current and upcoming CMB experiments such as SPT-3G, Simons Observatory, and CMB-S4, including multi-wavelength studies with facilities such as VRO-LSST. © 2023, CC BY.

关键词： Active Galactic Nuclei

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Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

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The Lancet 2023年第10397期402卷 203-234页

作者： Ong, Kanyin Liane Stafford, Lauryn K. McLaughlin, Susan A. Boyko, Edward J. Vollset, Stein Emil Smith, Amanda E. Dalton, Bronte E. Duprey, Joe Cruz, Jessica A. Hagins, Hailey Lindstedt, Paulina A. Aali, Amirali Abate, Yohannes Habtegiorgis Abate, Melsew Dagne Abbasian, Mohammadreza Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Mohsen ElHafeez, Samar Abd Abd-Rabu, Rami Abdulah, Deldar Morad Abdullah, Abu Yousuf Md Abedi, Vida Abidi, Hassan Aboagye, Richard Gyan Abolhassani, Hassan Abu-Gharbieh, Eman Abu-Zaid, Ahmed Adane, Tigist Demssew Adane, Denberu Eshetie Addo, Isaac Yeboah Adegboye, Oyelola A. Adekanmbi, Victor Adepoju, Abiola Victor Adnani, Qorinah Estiningtyas Sakilah Afolabi, Rotimi Felix Agarwal, Gina Aghdam, Zahra Babaei Agudelo-Botero, Marcela Arriagada, Constanza Elizabeth Aguilera Agyemang-Duah, Williams Ahinkorah, Bright Opoku Ahmad, Danish Ahmad, Rizwan Ahmad, Sajjad Ahmad, Aqeel Ahmadi, Ali Ahmadi, Keivan Ahmed, Ali Ahmed, Luai A. Ahmed, Syed Anees Ajami, Marjan Akinyemi, Rufus Olusola Al Hamad, Hanadi Al Hasan, Syed Mahfuz AL-Ahdal, Tareq Mohammed Ali Alalwan, Tariq A. Al-Aly, Ziyad AlBataineh, Mohammad T. Alcalde-Rabanal, Jacqueline Elizabeth Alemi, Sharifullah Ali, Hassam Alinia, Tahereh Aljunid, Syed Mohamed Almustanyir, Sami Al-Raddadi, Rajaa M. Alvis-Guzman, Nelson Amare, Firehiwot Ameyaw, Edward Kwabena Amiri, Sohrab Amusa, Ganiyu Adeniyi Andrei, Catalina Liliana Anjana, Ranjit Mohan Ansar, Adnan Ansari, Golnoosh Ansari-Moghaddam, Alireza Anyasodor, Anayochukwu Edward Arabloo, Jalal Aravkin, Aleksandr Y. Areda, Demelash Arifin, Hidayat Arkew, Mesay Armocida, Benedetta Arnlov, Johan Artamonov, Anton A. Arulappan, Judie Aruleba, Raphael Taiwo Arumugam, Ashokan Aryan, Zahra Asemu, Mulu Tiruneh Asghari-Jafarabadi, Mohammad Askari, Elaheh Asmelash, Daniel Astell-Burt, Thomas Athar, Mohammad Athari, Seyyed Shamsadin Atout, Maha Moh'd Wahbi Avila-Burgos, Leticia Awaisu, Ahmed Azadnajafabad, Sina Darshan, B.B. Babamohamadi, Hassan Badar, Muhammad Badawi, Alaa Badiye, Ashish D. Baghcheghi, Nayereh Baghe Institute for Health Metrics and Evaluation School of Medicine General Medicine Service Department of Veterans Affairs Seattle WA United States Department of Health Metrics Sciences School of Medicine Faculty of Medicine France Department of Clinical Governance and Quality Improvement Aleta Wondo Hospital Aleta Wondo Ethiopia Department of Nursing Woldia University Woldia Ethiopia Department of Nursing Department of Orthopedic Surgery Orthopaedic Surgery Social Determinants of Health Research Center Non-communicable Diseases Research Center Epidemiology Department Evidence-Based Practice Center Community and Maternity Nursing Unit University of Duhok Duhok Iraq School of Planning Faculty of Environment Department of Public Health Sciences Penn State College of Medicine Pennsylvania State University Hershey PA United States Biocomplexity Institute Virginia Tech Blacksburg VA United States College of Medicine Department of Public Health Laboratory Technology Sciences Department Department of Family and Community Health University of Health and Allied Sciences Ho Ghana Research Center for Immunodeficiencies Department of Biosciences and Nutrition Karolinska University Hospital Huddinge Sweden Clinical Sciences Department Department of Surgery Department of Surgery Department of Obstetrics & Gynecology College of Graduate Health Sciences University of Tennessee Memphis TN United States Department of Obstetrics & Gynecology Department of Clinical and Psychosocial Epidemiology Department of Anesthesia and Critical Care Centre for Social Research in Health Quality and Systems Performance Unit Cancer Institute NSW Sydney NSW Australia Department of Public Health and Tropical Medicine HIV and Infectious Diseases Department Jhpiego Abuja Nigeria Adolescent Research and Care Department Adolescent Friendly Research Initiative and Care Ado Ekiti Nigeria Department of Epidemiology Department of Epidemiology and Medical Statistics Department of Family Medicine McMaster University

Background: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. Methods: Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined;these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs;defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims;type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative r

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