Biodegradable polymers with high mechanical strength, flexibility and optical transparency, optimal degradation properties and biocompatibility are critical to the success of tissue engineered devices and drug deliver...
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Biodegradable polymers with high mechanical strength, flexibility and optical transparency, optimal degradation properties and biocompatibility are critical to the success of tissue engineered devices and drug deliver...
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Biodegradable polymers with high mechanical strength, flexibility and optical transparency, optimal degradation properties and biocompatibility are critical to the success of tissue engineered devices and drug delivery systems. In this work, microfluidic devices have been fabricated from elastomeric scaffolds with tunable degradation properties for applications in tissue engineering and regenerative medicine. Most biodegradable polymers suffer from short half life resulting from rapid and poorly controlled degradation upon implantation, exceedingly high stiffness, and limited compatibility with chemical functionalization. Here we report the first microfluidic devices constructed from a recently developed class of biodegradable elastomeric poly(ester amide)s, poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate)s (APS), showing a much longer and highly tunable in vivo degradation half-life comparing to many other commonly used biodegradable polymers. The device is molded in a similar approach to that reported previously for conventional biodegradable polymers, and the bonded microfluidic channels are shown to be capable of supporting physiologic levels of flow and pressure. The device has been tested for degradation rate and gas permeation properties in order to predict performance in the implantation environment. This device is high resolution and fully biodegradable; the fabrication process is fast, inexpensive, reproducible, and scalable, making it the approach ideal for both rapid prototyping and manufacturing of tissue engineering scaffolds and vasculature and tissue and organ replacements.
There have been reports of improvements in the thermoelectric figure of merit through the use of nanostructured materials to suppress the lattice thermal conductivity. Here, we report on a fundamental study of the com...
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作者：
Jae Ok KimHyeon Ju RyuWoo SeokNohJae Cheol ParkDepartment of Applied Chemistry
Kumoh National Institute of Technology1 Yangho-dongGumiGyeongbuk730-701Korea Department of Polymer Science and EngineeringKumoh National Institute of Technology1 Yangho-dongGumiGyeongbuk730-701Korea Department of Environmental EngineeringKumoh National Institute of Technology1 Yangho-dongGumiGyeongbuk730-701Korea
There have been reports of improvements in the thermoelectric figure of merit through the use of nanostructured materials to suppress the lattice thermal conductivity. Here, we report on a fundamental study of the com...
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There have been reports of improvements in the thermoelectric figure of merit through the use of nanostructured materials to suppress the lattice thermal conductivity. Here, we report on a fundamental study of the combined effects of defect planes and surface scattering on phonon transport and thermoelectric properties of defect-engineered InAs nanowires. A microfabricated device is employed to measure the thermal conductivity and thermopower of individual suspended indium arsenide nanowires grown by metal organic vapor phase epitaxy. The four-probe measurement device consists of platinum resistance thermometers and electrodes patterned on two adjacent SiNx membranes. A nanowire was suspended between the two membranes, and electrical contact between the nanowire and the platinum electrodes was made with the evaporation of a Ni/Pd film through a shadow mask. The exposed back side of the device substrate allows for characterization of the crystal structure of the suspended nanowire with transmission electron microscopy (TEM) following measurement. The 100-200 nm diameter zincblende (ZB) InAs nanowire samples were grown with randomly spaced twin defects, stacking faults, or phases boundaries perpendicular to the nanowire growth direction, as revealed by transmission electron microscopy (TEM) analysis. Compared to single-crystal ZB InAs nanowires with a similar lateral dimension, the thermal conductivity of the defect-engineered nanowires is reduced by fifty percent at room temperature.
Thermally-induced polymerization of 1,4-diphenyl-1,2,3-butatriene affords poly(1,4-diphenyl- 2-butyne-1,4-diyl) as a soluble high molecular weight material. Structure is characterized by 13C and vibrational spectrosco...
Thermally-induced polymerization of 1,4-diphenyl-1,2,3-butatriene affords poly(1,4-diphenyl- 2-butyne-1,4-diyl) as a soluble high molecular weight material. Structure is characterized by 13C and vibrational spectroscopy. When treated with base, this material rearranges to a soluble red poly(acetylene) with a unique substitution pattern.
Research and development in textiles have gone beyond the conventional applications as clothing and furnishing materials;for example, the convergence of textiles, nanotechnologies, and energy science opens up the oppo...
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Research and development in textiles have gone beyond the conventional applications as clothing and furnishing materials;for example, the convergence of textiles, nanotechnologies, and energy science opens up the opportunity to take on one of the major challenges in the 21st century-energy. This presentation addresses the development of high-energy lithium-ion batteries using electrospun nanofibers.
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