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Mimicking bone remodeling scaffolds of polyvinylalcohol/silk fibroin with phytoactive compound of soy protein isolate as surgical supporting biomaterials for tissue formation at defect area in osteoporosis;characterization, morphology, and in-vitro testing

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BIOMEDICAL MATERIALS 2025年第2期20卷 025046-025046页

作者： Watcharajittanont, Nattawat Jatuworapruk, Kanon Prarokijjak, Worasak Sangsuwan, Prawichaya Meesane, Jirut Thammasat Univ Fac Learning Sci & Educ Pathum Thani Thailand Thammasat Univ Fac Med Dept Med Pathum Thani Thailand Prince Songkla Univ Fac Sci Mol Biol & Bioinformat Program Biol Sci Div Hat Yai Thailand Prince Songkla Univ Inst Biomed Engn Fac Med Dept Biomed Sci & Biomed Engn Hat Yai Thailand

Mimicking bone remodeling scaffolds were developed as supportive biomaterials to promote tissue formation at defect sites in osteoporosis. Scaffolds made of polyvinyl alcohol (PVA) were mixed with varying weight ratios of silk fibroin (SF) and a phytoactive compound-based soy protein isolate (SPI);PVA30SF, PVA20SF10SPI, PVA15SF15SPI, PVA10SF20SPI, PVA30SPI. PVA was used as control. These components were mixed into aqueous solution and crosslinking with EDC before freeze thawing and freeze drying, respectively. Then, the scaffolds were characterized at the molecular level using Fourier transform infrared spectroscopy and their morphology was observed using scanning electron microscopy. Physical properties including swelling and degradation were tested, as well as mechanical properties like stress-strain behavior and modulus. The biological performance of the scaffolds was evaluated through osteoblast cell culturing, assessing cell viability, proliferation, alkaline phosphatase (ALP) activity, calcium content, and calcium deposition. The results demonstrate that the scaffolds with both SF and SPI had greater molecular mobility of -OH, amide I, II, and III groups, compared to the scaffold with only SF or SPI. These scaffolds also displayed larger pore sizes. Scaffolds with both SF and SPI showed higher swelling and degradation rates than those with only SF or SPI. Additionally, they exhibited better cell viability and calcium deposition, along with increased cell proliferation, ALP activity, and calcium content. Notably, the scaffold with a higher amount of SPI, PVA10SF20SPI, exhibited the most suitable performance for enhancing cell response, thereby promoting bone formation. This scaffold is proposed as a supportive biomaterial to be incorporated with plates and screws for bone fixation at defect sites in osteoporosis.

关键词： mimicking tissue scaffolds polyvinylalcohol silk fibroin soy protein isolate bone tissue engineering osteoporosis

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Assessing the educational impact of extended reality applications: Development and validation of a holistic evaluation tool

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EDUCATION AND INFORMATION TECHNOLOGIES 2025年 1-50页

作者： Lampropoulos, Georgios Chen, Nian-Shing Univ Macedonia Sch Informat Sci Dept Appl Informat Thessaloniki 54636 Greece Univ Nicosia Sch Educ Dept Educ CY-2417 Nicosia Cyprus Natl Taiwan Normal Univ Inst Res Excellence Learning Sci 129Sect 1Heping E Rd Taipei City 106 Taiwan Natl Taiwan Normal Univ Program Learning Sci 129Sect 1Heping E Rd Taipei City 106 Taiwan

This study aims to create and validate an evaluation tool that assesses the learning effectiveness of extended reality applications (e.g., augmented reality, virtual reality, mixed reality, and the metaverse). Six research questions were formulated to guide this study. The Extended Reality in Education (XREd) questionnaire consists of 50-items derived from 25 existing and validated questionnaires and surveys. The tool uses a 1-5 Likert scale and its items correspond to 15 factors, which are categorized into 5 dimensions. Both the factors and dimensions are supported by related theoretical aspects and background, and are grouped as follows: (1) System usability: Ease of use and Instructional clarity, (2) Learner's basic psychological needs: Enjoyment, Autonomy, Self-efficacy, and Social interaction, (3) Learner's learning state: Flow, Presence, and Immersion, (4) Learner's learning performance: learning outcomes, learning motivation, and learning engagement, (5) Learner's learning perceptions: Perceived usefulness, learning preferences alignment, and Behavioral intention. To validate the tool, descriptive statistics and reliability tests, validity tests, and factor analyses, Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA), and Structural Equation Modelling (SEM) were used. An extended reality application was developed and applied in higher education settings over the course of a semester. The experiment data was used to validate the created evaluation tool, which was then used to evaluate the effectiveness of the developed XR application and to answer the 6 research questions set to be explored. The results confirmed the validity of the XREd questionnaire and its effectiveness in evaluating extended reality applications. Additionally, its potential to be modularly integrated to evaluate non-extended reality learning applications was highlighted. Finally, the developed application was positively assessed by students, who regarded it as an effecti

关键词： Extended reality Augmented reality Virtual reality Evaluation Validation learning outcomes learning effectiveness

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Can generative AI help realize the shift from an outcome-oriented to a process-outcome-balanced educational practice?

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EDUCATIONAL TECHNOLOGY & SOCIETY 2024年第2期27卷 347-385页

作者： Chiang, Yueh-hui Vanessa Chang, Maiga Chen, Nian-Shing Dharma Drum Inst Liberal Arts Life Educ MA Program New Taipei Taiwan Athabasca Univ Sch Comp & Informat Syst Athabasca AB Canada Natl Taiwan Normal Univ Inst Res Excellence Learning Sci Taipei Taiwan Natl Taiwan Normal Univ Program Learning Sci Taipei Taiwan

Generative Artificial Intelligence (AI), especially machine learning models that autonomously generate human-like content, has recently attracted significant attention in the education sector. This paper explores the potential of generative AI, including tools like ChatGPT, to shift from traditional outcome-oriented educational practices to a more balanced approach that values both the learning process and its outcomes. Traditionally, education has emphasized achieving predefined results, but the advent of generative AI tools, which enable students to easily produce tangible results, calls for a reevaluation of these practices. This shift suggests a need for a broader focus that encompasses the entire learning process leading to the final product, thereby promoting an educational practice that equally emphasizes both the journey and the destination of learning. Recognizing that the implementation of such practices, facilitated by generative AI, still requires exploration, this paper proposes a solution that integrates the experiential learning cycle and learning portfolio. This approach is designed to demonstrate the realization of process-outcome-balanced educational practices through the use of a pedagogical AI agent.

关键词： Generative artificial intelligence (GAI) Process-outcome-balanced educational practice Experiential learning cycle Multimodal learning portfolio Pedagogical AI agent

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Shell's Strategic Competence Development: Ensuring Capability and Capacity Building Across the Global Operational Safety Skill Pool

Shell's Strategic Competence Development: Ensuring Capabilit...

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2024 SPE International Health, Safety, Environment and Sustainability Conference and Exhibition, HSE 2024

作者： Gosselin, Allan Abbasi, Shariq Richards, Angela Global Program Manager Operational Safety Shell Global Solutions CalgaryAB Canada Manager Learning Safety Shell India Markets Pvt. Ltd. Bangalore India Shell International Limited London United Kingdom

ISBN: (纸本)9781959025337

Competence development is an important aspect of career growth and development at Shell. As a result of a project in 2023, we now have a global central Competence Development SharePoint site with an electronic Self-Assessment Tool that helps our global Operational Safety skill pool community to identify and develop opportunities from the competencies required for their role (both current and future);assess their level of proficiency;(knowledge, skill and mastery) and create a development plan to acquire the necessary skills and knowledge for in-role and career progression and development. Our vision involves establishing an adaptive and robust Safety discipline, supporting Shell's strategy to create more value with less emissions. We envisage motivated employees, who know that their expertise is highly valued, have clear visibility of their career options and are empowered to strive for excellence. We aim to achieve this vision through three primary pillars. Capacity: Grow the talent pipeline with organizational focus where we attract, retain and develop talent who are competitive both inside and outside our function. Capability: building capability individual focused, maintain and build the capability to meet the business challenges and delivery of Shell's strategy. Community: strengthen the technical community through an active and proud community aligned with the business needs, leading safety performance through the energy transition. The purpose of the Operational Safety skill pool is to achieve Goal Zero by building a strong culture where everyone is motivated to relentlessly pursue no harm to people and to protect the environment. Partnering with businesses, assets, and sites to provide support with general Safety management, Contractor HSSE Management, High Risk Transport, Personal Safety & Human Performance, Project Safety, Safe Systems of Work, Emergency Management, and Incident Investigation & learning. For the ¬1200 staff and contractors in the Safety sk

关键词： Contractors

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Developmental pathways to pathological gambling and reasons for treatment seeking in a Greek rural sample

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JOURNAL OF SUBSTANCE USE 2024年第6期29卷 1007-1014页

作者： Smyrnaki, Maria Skoulas, Mihalis Liodaki, Athina Papadimitriou, Dimitris Papanastasatos, Gerasimos Tsiboukli, Anna Treatment Program Dependent Individuals Ketheas Ariadni Open Care Unit Iraklion Greece Ketheas Ariadni Treatment Program Dependent Indivi Iraklion Greece Ketheas Ariadni Res Dept Treatment Program Dependent Individuals Iraklion Greece Treatment Program Dependent Individuals Ketheas Psychiat Comorbid Unit Athens Greece Therapy Ctr Dependent Individuals Ketheas Res Dept Athens Greece Natl & Kapodistrian Univ Athens Sch Educ Dept Pedag & Primary Educ Lifelong LearningGrp Dynam & Adult Educ Athens Greece Treatment Program Dependent Individuals Ketheas Ariadni Open Care Unit Parodos Sgouromallinis 1A Iraklion 71305 Crete Greece

AimThe aim of this study is to understand the developmental pathways of pathological gambling and reasons for treatment *** study featuring the use of semi-structured interviews of 32 adults who gambled pathologically and participated in treatment groups at KETHEA's ARIADNI Open Care Unit in Heraklion Crete, *** of gambling varied from 13 to 37 years of age, with the majority reporting starting gambling at 15, mainly through betting. Pathological gambling onset age ranges from 20 to 30 years. The most frequent reasons that were reported to contribute in the establishment of excessive betting were traumatic experiences due to death or other loss, marital partnership dysfunctions, and lack of job satisfaction. Most participants asked for professional help between two (2) to 10 years after the establishment of pathological gambling. Most reported that they were motivated to seek treatment by significant others (family, friends). In addition, the majority reported that they used to punt at that time of seeking *** gambling follows a developmental pathway, unique for each case, where certain factors relevant to gambling establishment seem to play a significant role. Thus, they should be taken into consideration in any prevention and treatment efforts.

关键词： Pathological gambling developmental pathways treatment seeking

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Mobile Based Brand and Car Type Detection Using Convolutional Neural Network 8

Mobile Based Brand and Car Type Detection Using Convolutiona...

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8th International Conference on Computer Science and Computational Intelligence, ICCSCI 2023

作者： Ramadhan, Cahaya Saputra, Hasta Ragil Dewi, Ratna Sari Suharjito Computer Science Department BINUS Online Learning Bina Nusantara University Jakarta11480 Indonesia Industrial Engineering Department BINUS Graduate Program Bina Nusantara University Jakarta11480 Indonesia

Although the parking lot is equipped with CCTV surveillance, car theft incidents still occur occasionally. These thieves exploit a loophole in the system that prevents the identification of the car's brand and model upon entering and exiting the parking lot using the same ticket. Therefore, the aim of this research is to develop a system capable of detecting the brand and model of cars. The study utilizes convolutional neural network technology and specifically focuses on the EfficientNet, MobileNet, and MobileNetV2 architectures due to their low resource requirements. Training images for the study are sourced from an online marketplace for used cars, with each of the 20 car brand and model variations consisting of 100 photographs. creates a model after being processed. For the prototype, the approach is put into practice through a mobile application. This study compares EfficientNet, MobileNetV1, and MobileNetV2 as the end result. EfficientNet scored 74%, MobileNetV1 74%, and MobileNetV2 66% on the test of accuracy. The accuracy increases to 80% after the EfficientNet has been tuned. © 2023 The Authors. Published by Elsevier B.V.

关键词： Convolutional Neural Network EfficientNet MobileNet V2 MobileNetV1 Parking system Transfer learning

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Argumentative Segmentation Enhancement for Legal Summarization 6

Argumentative Segmentation Enhancement for Legal Summarizati...

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6th Workshop on Automated Semantic Analysis of Information in Legal Text, ASAIL 2023

作者： Xu, Huihui Ashley, Kevin Intelligent Systems Program University of Pittsburgh PA United States School of Law University of Pittsburgh PA United States Learning Research and Development Center University of Pittsburgh PA United States

We use the combination of argumentative zoning [1] and a legal argumentative scheme to create legal argumentative segments. Based on the argumentative segmentation, we propose a novel task of classifying argumentative segments of legal case decisions. GPT-3.5 is used to generate summaries based on argumentative segments. In terms of automatic evaluation metrics, our method generates higher quality argumentative summaries while leaving out less relevant context as compared to GPT-4 and non-GPT models. © 2023 Copyright for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).

关键词： Authentication

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Twelve-month outcomes of a community-based, father-daughter physical activity program delivered by trained facilitators

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INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY 2024年第1期21卷 101页

作者： Ashton, Lee M. Rayward, Anna T. Pollock, Emma R. Kennedy, Stevie-Lee Young, Myles D. Eather, Narelle Barnes, Alyce T. Lee, Daniel R. Morgan, Philip J. Univ Newcastle Coll Human & Social Futures Ctr Act Living & Learning Sch Educ Univ Dr Callaghan NSW 2308 Australia Hunter Med Res Inst HMRI Act Living & Learning Res Program Lot 1 Kookaburra Circuit New Lambton Hts NSW 2305 Australia Univ Newcastle Sch Med & Publ Hlth Newcastle NSW Australia Univ Newcastle Natl Ctr Implementat Sci NCOIS Newcastle NSW Australia Hunter Med Res Inst Populat Hlth Res Program New Lambton Hts NSW Australia Hunter New England Local Hlth Dist Hunter New England Populat Hlth Newcastle NSW Australia Univ Newcastle Coll Engn Sci & Environm Sch Psychol Callaghan NSW Australia

Background Dads and Daughters Exercising and Empowered (DADEE) is a program targeting fathers/father-figures to improve their daughters' physical activity and well-being. Previous randomised controlled efficacy and effectiveness trials of DADEE demonstrated meaningful improvements in a range of holistic outcomes for both fathers and daughters in the short-term. This study aims to assess the long-term impact (12-months) of the program when delivered in the community by trained facilitators. Methods Fathers/father-figures and their primary school-aged daughters were recruited from Newcastle, Australia into a single-arm, non-randomised, pre-post study with assessments at baseline, 10-weeks (post-intervention) and 12-months. The 9-session program included weekly 90-min educational and practical sessions, plus home-based tasks. The primary outcome was fathers' and daughters' days per week meeting national physical activity recommendations (>= 30 min/day of MVPA for fathers, >= 60 min/day MVPA for daughters). Secondary outcomes included physical activity, screen time, self-esteem, father-daughter relationship, social-emotional well-being, parenting measures, and process outcomes (including recruitment, attendance, retention and program acceptability). Results Twelve programs were delivered with 257 fathers (40.0 +/- 9.2 years) and 285 daughters (7.7 +/- 1.9 years). Mixed effects regression models revealed significant intervention effects for the primary outcome, with fathers increasing the days/week meeting physical activity recommendations by 27% at 10-weeks (p < 0.001) and by 19% at 12-months (p < 0.001) compared with baseline. Likewise, for daughters there was a significant increase by 25% at 10-weeks (p < 0.001) and by 14% at 12-months (p = 0.02) when compared to baseline. After conducting a sensitivity analysis with participants unaffected by COVID-19 lockdowns (n = 175 fathers, n = 192 daughters), the primary outcome results strengthened at both time-points for fath

关键词： Fathers Girls Community Physical activity Parenting

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Using Self-Determination Theory to Examine Student Responses to Five-Minute Self-Regulation Strategies in the Engineering Classroom 53

Using Self-Determination Theory to Examine Student Responses...

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53rd IEEE ASEE Frontiers in Education International Conference, FIE 2023

作者： Ramsey, Harly Loppacher, Julie Viterbi School of Engineering University of Southern California Engineering in Society Program Los Angeles United States Kortschak Center for Learning and Creativity University of Southern California Los Angeles United States

ISBN: (纸本)9798350336429

Contribution: This Work-in-Progress paper shares the pilot effort of an engineering educator partnering with an academic support service director to implement a series of five-minute interventions introducing students to self-regulation techniques in a classroom environment. The ability of self-regulation is approached as both as a fundamental criteria of learning motivation and as a valuable skill in its own right. Background: Engineering stress culture is increasingly recognized as negatively affecting engineering students. This paper investigates whether spending the first five minutes of each class teaching and modeling a series of research-based self-regulation techniques could have positive benefits toward promoting student's basic psychological needs (BPN) of autonomy, competence, and relatedness. Through Self-Determination Theory, BPN have been connected to learning and motivation. Research Question: Which, if any, of the basic psychological needs would students express as addressed by short in-class self-regulation interventions? Methodology: Semi-structured interviews of volunteer participants yielded rich, detailed data that was analyzed through a deductive thematic approach. Limitations of the study include its small sample size. Findings: The results suggest positive promotion of each of the BPNs, with particularly powerful feedback about the students' perception of relatedness. © 2023 IEEE.

关键词： basic psychological needs Self-Determination Theory self-regulation stress

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Why Do Influential Consumers Share Product Insights on Social Media? A Use and Gratification Theory Perspective 12th

Why Do Influential Consumers Share Product Insights on Socia...

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12th International Conference on HCI in Business, Government and Organizations, held as part of the 27th HCI International Conference, HCII 2025

作者： Chu, Tsai-Hsin Huang, Shiang-Chi Lee, Yen-Hsien Department of E-Learning Design and Management National Chiayi University Chiayi City Taiwan EMBA Program College of Management National Chiayi University Chiayi City Taiwan Department of Management Information Systems National Chiayi University Chiayi City Taiwan

ISBN: (纸本)9783031928222

Technological advancements and the growth of e-commerce have made online shopping increasingly common each year. Recently, the rise of Key Opinion Consumers (KOCs) has created new opportunities for online marketing. KOCs are influential consumers on social media who share authentic experiences and interactions, allowing them to connect more effectively with the public. Recognizing their impact, businesses have started inviting KOCs to experience and promote their products. However, the reasons behind KOCs’ willingness to share product information are worth investigating. Drawing from the Uses and Gratifications Theory (UGT), this study explores the motivational factors driving KOCs to use social media platforms to share product information. Through two stages of research, our findings reveal that KOCs are motivated to share based on three types of gratifications: emotional fulfillment, social interaction, and utilitarian benefits. While none of these identified gratifications affect the frequency of sharing, increased sharing frequency can enhance the gratification obtained from social interactions and utilitarian benefits. This results also indicate that KOCs value GO more than GS when sharing their consumption experiences on social media. This study contributes to theoretical development by establishing a framework that explains the gratifications KOCs seek when sharing product information and the gratifications they receive afterward. The framework also extends the application of UGT to social media and word-of-mouth marketing, thereby deepening our understanding of why KOCs choose to share product information. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

关键词： Tweets

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